## Mon Dec 15 18:51:11 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158535_bin.7.fa -m mmseqs --itype genome -o SRR25158535_bin.7 --output_dir /data/result/bins/wyx/egg/SRR25158535_bin.7 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158535_k127_1034271_24	485913.Krac_10317	1.444e-36	147.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_1034271_23	269797.Mbar_A2345	1.905e-42	162.0	COG2032@1|root,arCOG05224@2157|Archaea,2Y3M1@28890|Euryarchaeota,2NAVG@224756|Methanomicrobia	224756|Methanomicrobia	P	Copper/zinc superoxide dismutase (SODC)	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SRR25158535_k127_1034271_6	1128421.JAGA01000002_gene1223	7.368e-103	366.0	COG0247@1|root,COG0247@2|Bacteria,2NNU8@2323|unclassified Bacteria	2|Bacteria	C	Cysteine-rich domain	glcF	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	iAPECO1_1312.glcF,iECABU_c1320.ECABU_c33760,iECIAI1_1343.ECIAI1_3119,iECIAI39_1322.ECIAI39_3465,iECNA114_1301.ECNA114_3053,iECP_1309.ECP_3055,iJN678.glcF,iJN746.PP_3747,iUTI89_1310.glcF,ic_1306.glcF	CCG,Fer4_7,Fer4_8
SRR25158535_k127_1034271_20	324602.Caur_1144	1.067e-53	216.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_1034271_2	309801.trd_0260	5.343e-138	456.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_1034271_21	502025.Hoch_4729	8.949e-53	193.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158535_k127_1034271_7	266117.Rxyl_1072	9.291e-101	345.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158535_k127_1034271_28	1510531.JQJJ01000017_gene4320	2.134e-30	135.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,3JRDM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158535_k127_1034271_22	555079.Toce_2275	7.547e-48	183.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158535_k127_1034271_16	525904.Tter_2844	4.007e-68	241.0	COG1192@1|root,COG1192@2|Bacteria,2NQVW@2323|unclassified Bacteria	2|Bacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158535_k127_1034271_12	479434.Sthe_3384	8.913e-84	289.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_1034271_27	1120934.KB894441_gene5662	8.013e-31	138.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR25158535_k127_1034271_32	1382306.JNIM01000001_gene4173	4.929e-20	98.0	COG2059@1|root,COG2059@2|Bacteria	2|Bacteria	P	chromate transport	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_1034271_33	485913.Krac_8723	6.685e-13	81.0	COG2059@1|root,COG2059@2|Bacteria	2|Bacteria	P	chromate transport	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_1034271_35	67275.JOAP01000106_gene2952	3.274e-08	62.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	CHRD,DUF839,HemolysinCabind,Phytase-like
SRR25158535_k127_1034271_0	290397.Adeh_0397	3.68e-187	606.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YUF2@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158535_k127_1034271_5	469383.Cwoe_4979	5.519e-108	370.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CR9E@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158535_k127_1034271_15	604331.AUHY01000004_gene912	1.636e-70	263.0	COG3437@1|root,COG3437@2|Bacteria,1WM13@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158535_k127_1034271_31	867845.KI911784_gene3556	2.826e-22	103.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33,ROK
SRR25158535_k127_1034271_26	1254432.SCE1572_19175	1.038e-32	132.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_1034271_34	685778.AORL01000019_gene1855	1.042e-08	58.0	2EFZF@1|root,339RM@2|Bacteria,1Q79X@1224|Proteobacteria,2UWHC@28211|Alphaproteobacteria,2K7QX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1034271_37	661478.OP10G_4159	0.0009593	44.0	2EPV2@1|root,33HFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1034271_13	525904.Tter_1439	6.187e-83	285.0	COG1131@1|root,COG1131@2|Bacteria,2NQB3@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1034271_10	357808.RoseRS_2477	5.738e-87	296.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi,3768D@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_1034271_30	525904.Tter_1450	8.377e-25	110.0	2BVHN@1|root,32QW3@2|Bacteria	2|Bacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_1034271_1	479434.Sthe_2440	1.21e-182	593.0	COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158535_k127_1034271_36	479434.Sthe_1243	5.627e-06	59.0	2A4SM@1|root,30TE1@2|Bacteria,2GA2B@200795|Chloroflexi,27YRH@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1034271_4	357808.RoseRS_2614	3.915e-111	370.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi,3751G@32061|Chloroflexia	32061|Chloroflexia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158535_k127_1034271_25	644966.Tmar_0861	5.04e-34	136.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WD92@538999|Clostridiales incertae sedis	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158535_k127_1034271_8	309801.trd_0056	2.187e-94	323.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158535_k127_1034271_3	479434.Sthe_1996	9.172e-112	381.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158535_k127_1034271_9	867903.ThesuDRAFT_01663	2.394e-92	319.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WCHQ@538999|Clostridiales incertae sedis	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1034271_18	1297581.H919_02802	6.547e-62	225.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,21W1J@150247|Anoxybacillus	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158535_k127_1034271_29	292459.STH1225	9.163e-29	135.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia	186801|Clostridia	L	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158535_k127_1034271_11	1121468.AUBR01000006_gene362	1.29e-85	310.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1034271_14	1051632.TPY_3476	8.641e-83	310.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WCI1@538999|Clostridiales incertae sedis	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_1034271_17	1303518.CCALI_00972	2.358e-62	228.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
SRR25158535_k127_1034271_19	367299.JOEE01000004_gene1363	4.826e-58	223.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4FE62@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_104746_8	479434.Sthe_1928	2.848e-16	85.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,27YK5@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158535_k127_104746_2	525904.Tter_0058	1.092e-166	538.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_104746_3	525904.Tter_1745	3.56e-148	490.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_104746_7	66692.ABC3222	6.393e-25	115.0	COG1413@1|root,COG1413@2|Bacteria,1VQHH@1239|Firmicutes,4HR74@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_104746_4	1089548.KI783301_gene238	1.783e-145	477.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3WDZI@539002|Bacillales incertae sedis	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158535_k127_104746_1	1382304.JNIL01000001_gene3128	8.445e-208	669.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,279F3@186823|Alicyclobacillaceae	91061|Bacilli	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158535_k127_104746_6	479434.Sthe_3140	2.492e-42	180.0	COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,27XU2@189775|Thermomicrobia	189775|Thermomicrobia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158535_k127_104746_5	518766.Rmar_1448	1.393e-49	202.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1FIS0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158535_k127_104746_0	525904.Tter_1074	6.572e-289	915.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_1057207_12	157072.XP_008863939.1	7.221e-08	67.0	2CMRT@1|root,2QRKV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1057207_11	1198452.Jab_1c10470	1.192e-09	67.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1057207_13	522306.CAP2UW1_0976	2.298e-06	56.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1057207_4	426117.M446_3385	5.658e-63	248.0	COG2931@1|root,COG3055@1|root,COG3386@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.2.1.4	ko:K01179,ko:K07004,ko:K14274	ko00040,ko00500,ko01100,map00040,map00500,map01100	-	R02427,R06200,R11307,R11308	RC00713	ko00000,ko00001,ko01000	-	GH5,GH9	-	Malectin,SGL
SRR25158535_k127_1057207_14	886293.Sinac_7293	0.0002645	52.0	COG0457@1|root,COG0457@2|Bacteria,2J3HF@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SRR25158535_k127_1057207_1	671143.DAMO_0304	2.914e-156	530.0	2BPHD@1|root,32I9T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1057207_10	926569.ANT_15880	4.65e-14	85.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_1057207_7	877421.AUJT01000002_gene1207	8.018e-47	191.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27KU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_1057207_5	1961.JOAK01000009_gene6383	1.672e-58	222.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GZCD@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1057207_2	179408.Osc7112_4698	7.479e-140	472.0	COG0463@1|root,COG0463@2|Bacteria,1G4BG@1117|Cyanobacteria,1H8D9@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_1057207_9	485913.Krac_9427	8.722e-20	100.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1057207_6	1278073.MYSTI_04304	4.519e-54	199.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_1057207_3	545693.BMQ_2373	8.422e-109	369.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1ZAZ9@1386|Bacillus	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_1057207_0	525909.Afer_1025	0.0	1317.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158535_k127_1057207_8	1380356.JNIK01000003_gene1160	6.716e-42	174.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4ESCN@85013|Frankiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158535_k127_1057207_15	253839.SSNG_03082	0.0002763	53.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1060422_0	485913.Krac_8072	1.633e-149	511.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158535_k127_1060422_1	113395.AXAI01000002_gene5239	5.213e-38	154.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_1076208_1	479434.Sthe_3406	3.766e-57	205.0	COG0477@1|root,COG0642@1|root,COG0793@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG0477@2|Bacteria,COG0793@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia	189775|Thermomicrobia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD
SRR25158535_k127_1076208_3	867903.ThesuDRAFT_02369	5.106e-08	63.0	29Y0M@1|root,30JTI@2|Bacteria,1VEVD@1239|Firmicutes,24QVV@186801|Clostridia,3WDJ2@538999|Clostridiales incertae sedis	186801|Clostridia	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158535_k127_1076208_2	1463917.JODC01000008_gene3541	2.096e-21	109.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_1076208_0	525904.Tter_0790	1.034e-151	490.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712,ko:K07714	ko02020,map02020	M00497,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158535_k127_1076342_9	469383.Cwoe_4684	2.569e-19	98.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158535_k127_1076342_3	1121422.AUMW01000003_gene956	1.475e-109	367.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158535_k127_1076342_14	1284352.AOIG01000008_gene2251	0.0003637	54.0	COG1357@1|root,COG1357@2|Bacteria,1V8FP@1239|Firmicutes,4HHEX@91061|Bacilli,26TI8@186822|Paenibacillaceae	91061|Bacilli	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158535_k127_1076342_5	404589.Anae109_4500	1.338e-39	154.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158535_k127_1076342_4	710421.Mycch_1790	9.01e-52	192.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158535_k127_1076342_0	697303.Thewi_2280	6.705e-151	496.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158535_k127_1076342_2	479434.Sthe_1321	1.533e-129	424.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi,27Y08@189775|Thermomicrobia	189775|Thermomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158535_k127_1076342_10	1191523.MROS_0726	3.92e-11	66.0	2DNS1@1|root,32YVX@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2905)	yrzS	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158535_k127_1076342_11	926569.ANT_18000	1.872e-10	66.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158535_k127_1076342_7	1121861.KB899914_gene2072	1.447e-25	116.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRR25158535_k127_1076342_6	1382306.JNIM01000001_gene1590	5.085e-36	147.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158535_k127_1076342_1	717606.PaecuDRAFT_0645	1.519e-143	466.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,26QDU@186822|Paenibacillaceae	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_1076342_8	316274.Haur_4193	1.36e-22	104.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,375N3@32061|Chloroflexia	32061|Chloroflexia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158535_k127_1117924_7	697284.ERIC2_c11090	2.677e-51	192.0	COG0500@1|root,COG2226@2|Bacteria,1TRW7@1239|Firmicutes,4HJG4@91061|Bacilli,26VYB@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158535_k127_1117924_9	1128421.JAGA01000003_gene3046	5.087e-31	140.0	COG2340@1|root,COG2367@1|root,COG2340@2|Bacteria,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	ponA	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase2,CAP
SRR25158535_k127_1117924_3	1121926.AXWO01000001_gene3350	1.578e-74	257.0	COG0346@1|root,COG0346@2|Bacteria,2I6JC@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_4a
SRR25158535_k127_1117924_6	1206732.BAGD01000086_gene3817	2.017e-61	216.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria,4G3D8@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_1117924_2	926550.CLDAP_39930	2.518e-101	338.0	COG0437@1|root,COG0437@2|Bacteria,2G82U@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
SRR25158535_k127_1117924_4	926550.CLDAP_25500	7.835e-69	249.0	COG5557@1|root,COG5557@2|Bacteria,2G703@200795|Chloroflexi	200795|Chloroflexi	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158535_k127_1117924_0	401526.TcarDRAFT_0235	0.0	1265.0	COG0243@1|root,COG0243@2|Bacteria,1UYJX@1239|Firmicutes	1239|Firmicutes	C	belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158535_k127_1117924_5	326427.Cagg_3664	3.681e-68	237.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia	32061|Chloroflexia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
SRR25158535_k127_1117924_1	1312959.KI914644_gene1088	1.257e-118	388.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1117924_8	525904.Tter_2724	5.73e-42	160.0	COG3439@1|root,COG3439@2|Bacteria,2NPV1@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158535_k127_1123667_1	309801.trd_0202	2.307e-152	488.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
SRR25158535_k127_1123667_26	485913.Krac_9161	4.224e-12	79.0	2E48V@1|root,32Z4P@2|Bacteria,2G7HY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1123667_7	1128421.JAGA01000002_gene683	9.791e-70	241.0	COG0311@1|root,COG0311@2|Bacteria,2NPDR@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
SRR25158535_k127_1123667_3	1089553.Tph_c00140	2.139e-131	429.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,42EVS@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158535_k127_1123667_13	316274.Haur_4220	3.317e-50	188.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158535_k127_1123667_14	518766.Rmar_1131	1.465e-47	189.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1123667_16	518766.Rmar_1131	3.677e-37	154.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1123667_23	485913.Krac_7824	3.894e-19	91.0	COG0640@1|root,COG0640@2|Bacteria,2G7FZ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158535_k127_1123667_6	1184609.KILIM_026_00290	9.781e-70	243.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158535_k127_1123667_18	479434.Sthe_0659	6.554e-34	144.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,27Y5T@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158535_k127_1123667_12	485913.Krac_8672	1.742e-51	205.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158535_k127_1123667_10	1463825.JNXC01000001_gene6094	1.66e-56	209.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4DY0P@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158535_k127_1123667_4	926550.CLDAP_37440	1.436e-126	435.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158535_k127_1123667_8	370438.PTH_0147	2.576e-68	246.0	COG1672@1|root,COG1672@2|Bacteria,1TPMK@1239|Firmicutes,24CZS@186801|Clostridia,264P1@186807|Peptococcaceae	186801|Clostridia	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
SRR25158535_k127_1123667_24	1033730.CAHG01000012_gene2113	4.468e-19	92.0	COG2261@1|root,COG2261@2|Bacteria,2I6N7@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158535_k127_1123667_11	525904.Tter_1640	1.201e-55	203.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158535_k127_1123667_2	404589.Anae109_0774	1.171e-137	453.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158535_k127_1123667_22	316274.Haur_0391	2.115e-19	96.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi,377N3@32061|Chloroflexia	32061|Chloroflexia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158535_k127_1123667_19	326427.Cagg_2913	9.557e-34	143.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_1123667_25	485913.Krac_8941	3.793e-16	83.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	DUF2087,HTH_20,HTH_5
SRR25158535_k127_1123667_21	1122182.KB903825_gene320	4.772e-22	107.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4DCRP@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158535_k127_1123667_0	324602.Caur_1572	5.21e-185	586.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158535_k127_1123667_17	1382306.JNIM01000001_gene4124	3.445e-36	156.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158535_k127_1123667_20	1382306.JNIM01000001_gene4123	1.179e-28	129.0	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158535_k127_1123667_15	1121946.AUAX01000010_gene3735	5.186e-38	152.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria,4DCZJ@85008|Micromonosporales	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158535_k127_1123667_5	243164.DET0978	3.521e-87	310.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,34CIQ@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1123667_9	504832.OCAR_7523	5.781e-58	209.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_1130739_5	459349.CLOAM1247	2.301e-68	250.0	COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria	2|Bacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158535_k127_1130739_13	2045.KR76_05040	4.415e-14	85.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4DRJG@85009|Propionibacteriales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158535_k127_1130739_14	869210.Marky_1889	1.443e-09	68.0	COG1295@1|root,COG1295@2|Bacteria,1WIGF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158535_k127_1130739_9	1521187.JPIM01000006_gene1731	1.495e-39	167.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158535_k127_1130739_12	525904.Tter_1426	2.768e-17	94.0	COG1716@1|root,COG1716@2|Bacteria,2NRHK@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158535_k127_1130739_2	479434.Sthe_1162	2.603e-93	331.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,27Y4C@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_1130739_4	580331.Thit_1767	9.21e-72	274.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,42FRP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM penicillin-binding protein transpeptidase	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158535_k127_1130739_1	383372.Rcas_0210	4.817e-131	431.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_1130739_6	383372.Rcas_2888	7.576e-64	234.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_1130739_3	1128421.JAGA01000002_gene1319	1.937e-82	302.0	COG1305@1|root,COG1305@2|Bacteria,2NQTS@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158535_k127_1130739_10	58344.JOEL01000015_gene6350	2.062e-34	153.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158535_k127_1130739_7	525904.Tter_2599	4.783e-57	216.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158535_k127_1130739_16	345341.KUTG_00761	5.11e-06	51.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_1130739_15	378806.STAUR_7037	5.213e-07	60.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YWC5@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158535_k127_1130739_8	635013.TherJR_0769	4.565e-48	178.0	COG0243@1|root,COG0243@2|Bacteria,1V2XY@1239|Firmicutes,24GWZ@186801|Clostridia,262P2@186807|Peptococcaceae	186801|Clostridia	C	PFAM molybdopterin oxidoreductase Fe4S4 region	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR25158535_k127_1130739_0	246194.CHY_0793	8.516e-266	841.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1TQIX@1239|Firmicutes,24B1X@186801|Clostridia,42FAV@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158535_k127_1130739_11	768704.Desmer_1537	8.014e-33	146.0	COG0437@1|root,COG0437@2|Bacteria,1TT2G@1239|Firmicutes,24DAZ@186801|Clostridia,261IB@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM formate dehydrogenase, beta subunit, Fe-S containing	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7,Form-deh_trans
SRR25158535_k127_1157156_11	748727.CLJU_c40290	3.764e-18	99.0	COG1266@1|root,COG1266@2|Bacteria,1VEJJ@1239|Firmicutes,24EDW@186801|Clostridia,36GT3@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158535_k127_1157156_6	748449.Halha_2023	7.534e-44	181.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,3WBTB@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS19835	UbiA
SRR25158535_k127_1157156_9	2002.JOEQ01000026_gene349	2.839e-28	132.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ3@201174|Actinobacteria	201174|Actinobacteria	C	PFAM luciferase-like	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158535_k127_1157156_7	635013.TherJR_2420	2.394e-41	165.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158535_k127_1157156_4	457429.ABJI02000612_gene2283	1.357e-64	232.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria	201174|Actinobacteria	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158535_k127_1157156_5	886293.Sinac_4911	4.869e-58	219.0	COG2124@1|root,COG2124@2|Bacteria,2IZTH@203682|Planctomycetes	203682|Planctomycetes	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158535_k127_1157156_0	177437.HRM2_26180	3.566e-156	537.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158535_k127_1157156_2	1382356.JQMP01000003_gene1858	2.063e-95	337.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158535_k127_1157156_1	290397.Adeh_1627	7.928e-110	382.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
SRR25158535_k127_1157156_8	292459.STH2305	6.505e-39	166.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_33,ADK,ADK_lid,SKI
SRR25158535_k127_1157156_10	1178540.BA70_17870	2.045e-18	99.0	COG2306@1|root,COG2306@2|Bacteria,1VTFM@1239|Firmicutes,4HURM@91061|Bacilli,1ZHM6@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF402
SRR25158535_k127_1157156_3	1125863.JAFN01000001_gene2796	1.877e-75	266.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
SRR25158535_k127_1182863_7	383372.Rcas_1748	5.453e-21	95.0	COG0714@1|root,COG0714@2|Bacteria,2GBIS@200795|Chloroflexi,37823@32061|Chloroflexia	32061|Chloroflexia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1182863_9	526226.Gbro_0535	4.706e-11	71.0	COG0863@1|root,COG0863@2|Bacteria,2HM0D@201174|Actinobacteria,4GGQ2@85026|Gordoniaceae	2|Bacteria	L	Eco29kI restriction endonuclease	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,RE_Eco29kI
SRR25158535_k127_1182863_0	1048834.TC41_2442	4.615e-117	389.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HDW0@91061|Bacilli	91061|Bacilli	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_26,HTH_3
SRR25158535_k127_1182863_5	485916.Dtox_1536	4.984e-27	117.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia	186801|Clostridia	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
SRR25158535_k127_1182863_4	383372.Rcas_1748	9.277e-29	122.0	COG0714@1|root,COG0714@2|Bacteria,2GBIS@200795|Chloroflexi,37823@32061|Chloroflexia	32061|Chloroflexia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1182863_8	693977.Deipr_2005	6.497e-20	101.0	COG1247@1|root,COG1670@1|root,COG1247@2|Bacteria,COG1670@2|Bacteria,1WNE2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	JM	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_1182863_1	383372.Rcas_3959	1.745e-44	185.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_1182863_2	479434.Sthe_1369	2.778e-37	159.0	COG1598@1|root,COG2318@1|root,COG1598@2|Bacteria,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
SRR25158535_k127_1182863_3	937777.Deipe_2518	6.028e-31	134.0	2EBVK@1|root,335V0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158535_k127_1182863_6	58123.JOFJ01000006_gene239	1.704e-21	101.0	COG3662@1|root,COG3662@2|Bacteria,2GY2Z@201174|Actinobacteria,4EQTZ@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158535_k127_1211103_4	76114.p2A102	1.446e-91	329.0	COG1804@1|root,COG1804@2|Bacteria,1NSWZ@1224|Proteobacteria,2WFDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158535_k127_1211103_5	76114.p2A104	8.718e-80	290.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158535_k127_1211103_0	76114.p2A133	4.564e-233	736.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W317@28216|Betaproteobacteria	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158535_k127_1211103_2	1500257.JQNM01000014_gene2941	1.46e-112	374.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1211103_7	1123023.JIAI01000003_gene2856	3.8e-40	161.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158535_k127_1211103_8	1120985.AUMI01000016_gene1936	2.22e-18	98.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4H2BE@909932|Negativicutes	909932|Negativicutes	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
SRR25158535_k127_1211103_1	1231391.AMZF01000063_gene1102	9.116e-142	469.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158535_k127_1211103_3	561175.KB894105_gene943	1.493e-98	355.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158535_k127_1211103_6	1231391.AMZF01000110_gene916	1.303e-75	263.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_1231066_1	309801.trd_A0888	2.927e-113	394.0	COG0465@1|root,COG0465@2|Bacteria,2G5JA@200795|Chloroflexi,27YWY@189775|Thermomicrobia	189775|Thermomicrobia	D	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158535_k127_1231066_11	94624.Bpet3563	4.905e-28	128.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,3T1RX@506|Alcaligenaceae	28216|Betaproteobacteria	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158535_k127_1231066_5	485913.Krac_0969	1.016e-75	273.0	COG1011@1|root,COG1011@2|Bacteria,2G9CU@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158535_k127_1231066_14	1027292.HMPREF9372_3571	8.499e-07	57.0	COG0695@1|root,COG0695@2|Bacteria,1VHHY@1239|Firmicutes,4HP37@91061|Bacilli,26G2H@186818|Planococcaceae	91061|Bacilli	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158535_k127_1231066_8	876269.ARWA01000001_gene2647	9.837e-50	198.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,3NA1M@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	sseA	GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_1231066_2	760568.Desku_0259	4e-112	376.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158535_k127_1231066_10	450851.PHZ_c0127	5.027e-38	163.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,2KFK1@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158535_k127_1231066_7	357808.RoseRS_3334	1.61e-58	229.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158535_k127_1231066_9	479434.Sthe_3135	6.633e-42	176.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27Y3Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_1231066_3	525904.Tter_2275	2.683e-99	333.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_1231066_6	671143.DAMO_0577	1.895e-67	241.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	trpH	-	3.1.3.97,4.1.2.13	ko:K01624,ko:K07053	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R00188,R01068,R01070,R01829,R02568,R11188	RC00078,RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158535_k127_1231066_4	1121430.JMLG01000001_gene2103	9.62e-82	279.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158535_k127_1231066_0	635013.TherJR_1279	4.096e-173	558.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158535_k127_1231066_12	37919.EP51_11010	3.667e-18	87.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4G30U@85025|Nocardiaceae	201174|Actinobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158535_k127_1231066_13	1121920.AUAU01000005_gene961	4.4e-17	94.0	COG0477@1|root,COG2814@2|Bacteria,3Y711@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1273511_5	234267.Acid_2815	1.366e-25	116.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_1273511_0	479434.Sthe_0497	1.745e-147	479.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,27XMK@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
SRR25158535_k127_1273511_2	485913.Krac_11275	2.008e-83	290.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158535_k127_1273511_4	404589.Anae109_2497	2.492e-31	137.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158535_k127_1273511_3	159087.Daro_1974	5.788e-46	181.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,2KWCF@206389|Rhodocyclales	206389|Rhodocyclales	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158535_k127_1273511_1	1195236.CTER_4205	7.228e-111	372.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158535_k127_1311419_6	525904.Tter_1346	4.475e-12	73.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158535_k127_1311419_1	1160707.AJIK01000003_gene645	1.203e-79	292.0	29MNG@1|root,308K7@2|Bacteria,1VTU1@1239|Firmicutes,4HTYB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1311419_5	926560.KE387025_gene4077	7.563e-13	80.0	COG2010@1|root,COG2010@2|Bacteria	926560.KE387025_gene4077|-	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1311419_0	866536.Belba_1302	2.538e-91	326.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158535_k127_1311419_4	694427.Palpr_2927	1.876e-53	197.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,2FWWQ@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
SRR25158535_k127_1311419_2	644966.Tmar_0771	2.485e-78	269.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1311419_3	937777.Deipe_0703	1.242e-55	215.0	COG5002@1|root,COG5002@2|Bacteria,1WMAK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1316412_3	1229172.JQFA01000002_gene5185	0.0009085	52.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
SRR25158535_k127_1316412_2	479434.Sthe_1019	4.74e-38	154.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2
SRR25158535_k127_1316412_1	1303518.CCALI_02333	7.223e-93	319.0	COG1873@1|root,COG2239@1|root,COG1873@2|Bacteria,COG2239@2|Bacteria	2|Bacteria	P	Acts as a magnesium transporter	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,DUF2171,MgtE_N,PRC
SRR25158535_k127_1316412_0	525904.Tter_2339	6.506e-101	350.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
SRR25158535_k127_1334580_11	1123368.AUIS01000006_gene560	1.579e-05	49.0	COG3861@1|root,COG3861@2|Bacteria,1RJWQ@1224|Proteobacteria,1T0VJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382
SRR25158535_k127_1334580_0	861299.J421_3807	4.113e-250	805.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158535_k127_1334580_1	448385.sce7170	1.276e-218	695.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WM5H@28221|Deltaproteobacteria,2YZJV@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3459)	treZ-2	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158535_k127_1334580_7	1048339.KB913029_gene2323	1.666e-22	108.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4ESI9@85013|Frankiales	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1334580_2	1122222.AXWR01000060_gene807	1.655e-85	292.0	COG1131@1|root,COG1131@2|Bacteria,1WM0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1334580_8	711393.AYRX01000010_gene2696	6.169e-13	83.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158535_k127_1334580_9	1183438.GKIL_2486	1.414e-09	67.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1334580_5	195105.CN97_16205	7.274e-49	189.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158535_k127_1334580_6	2074.JNYD01000026_gene643	1.103e-42	160.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria,4EBJD@85010|Pseudonocardiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158535_k127_1334580_4	1283299.AUKG01000001_gene1746	4.461e-58	225.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_1334580_10	1122919.KB905639_gene367	5.345e-09	69.0	2E4CV@1|root,32Z89@2|Bacteria,1VIUI@1239|Firmicutes,4I7WR@91061|Bacilli,26XYU@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1334580_3	1379270.AUXF01000001_gene2174	1.66e-67	253.0	COG0297@1|root,COG0297@2|Bacteria,1ZUGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158535_k127_1365439_1	926550.CLDAP_28550	1.364e-86	303.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158535_k127_1365439_3	1245475.ANAE01000092_gene393	4.956e-60	231.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1365439_0	1128421.JAGA01000001_gene2386	2.577e-118	392.0	COG2132@1|root,COG2132@2|Bacteria,2NPD2@2323|unclassified Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396
SRR25158535_k127_1365439_2	68170.KL590533_gene5191	1.538e-69	239.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4E0K7@85010|Pseudonocardiales	201174|Actinobacteria	P	haloacid dehalogenase-like hydrolase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_1397770_9	525904.Tter_2016	0.0003404	52.0	COG0672@1|root,COG1555@1|root,COG0672@2|Bacteria,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	ybaV	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.1.26.11	ko:K00784,ko:K02237,ko:K07243	ko03013,map03013	M00429	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044,ko03016	2.A.108.1,2.A.108.2,3.A.11.1,3.A.11.2	-	-	FTR1,HHH_3
SRR25158535_k127_1397770_6	644966.Tmar_1431	9.702e-36	145.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,24U9B@186801|Clostridia	186801|Clostridia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158535_k127_1397770_0	1051632.TPY_0663	4.41e-111	383.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158535_k127_1397770_3	675635.Psed_6017	8.064e-72	263.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4E1ST@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_1397770_5	926560.KE387023_gene1617	6.22e-45	181.0	COG1524@1|root,COG1524@2|Bacteria,1WKX5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158535_k127_1397770_2	357808.RoseRS_1928	3.899e-82	293.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,376TM@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase M48 Ste24p	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158535_k127_1397770_8	1123508.JH636441_gene3020	8.213e-10	71.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1397770_7	926560.KE387023_gene2190	4.646e-23	113.0	COG0406@1|root,COG0406@2|Bacteria,1WMW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158535_k127_1397770_4	263358.VAB18032_18690	5.321e-54	201.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria,4D96E@85008|Micromonosporales	201174|Actinobacteria	S	Involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_1397770_1	28444.JODQ01000006_gene14	1.124e-89	305.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1477456_2	717605.Theco_0203	8.982e-88	305.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,26SMJ@186822|Paenibacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158535_k127_1477456_0	479434.Sthe_0796	8.871e-281	880.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158535_k127_1477456_6	1121428.DESHY_10186___1	0.000174	53.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,262WB@186807|Peptococcaceae	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158535_k127_1477456_3	1121946.AUAX01000024_gene7573	8.786e-35	149.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DCAZ@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158535_k127_1477456_1	1382306.JNIM01000001_gene1813	9.977e-141	470.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158535_k127_1477456_4	485913.Krac_11273	1.101e-25	120.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
SRR25158535_k127_1477456_5	1120973.AQXL01000112_gene1044	1.497e-21	107.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,277VJ@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_1478226_3	383372.Rcas_1634	4.324e-127	415.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi,374YV@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158535_k127_1478226_7	326427.Cagg_3175	2.45e-68	258.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi,375FD@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158535_k127_1478226_6	448385.sce7756	1.493e-82	301.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,42P6E@68525|delta/epsilon subdivisions,2WISH@28221|Deltaproteobacteria,2YV40@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158535_k127_1478226_8	883.DvMF_1205	1.222e-36	160.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,42UKW@68525|delta/epsilon subdivisions,2WQIH@28221|Deltaproteobacteria,2M7SF@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158535_k127_1478226_4	266117.Rxyl_0919	2.221e-113	389.0	COG1144@1|root,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porD	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00171,ko:K00172,ko:K19072	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_21,POR
SRR25158535_k127_1478226_0	266117.Rxyl_0920	9.986e-177	561.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158535_k127_1478226_1	266117.Rxyl_0921	2.955e-152	490.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00170,ko:K19071	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158535_k127_1478226_2	1144275.COCOR_00586	4.211e-136	471.0	COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,42PE0@68525|delta/epsilon subdivisions,2WITD@28221|Deltaproteobacteria,2YUZH@29|Myxococcales	28221|Deltaproteobacteria	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
SRR25158535_k127_1478226_5	765420.OSCT_1145	3.169e-94	322.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1478226_10	525904.Tter_0780	6.227e-25	111.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
SRR25158535_k127_1478226_9	1121920.AUAU01000015_gene1140	3.253e-29	121.0	COG0629@1|root,COG0629@2|Bacteria,3Y4D2@57723|Acidobacteria	57723|Acidobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158535_k127_1478226_11	986075.CathTA2_2109	2.363e-16	83.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158535_k127_1546776_7	867903.ThesuDRAFT_01433	1.587e-07	55.0	COG0446@1|root,COG0446@2|Bacteria,1TRNN@1239|Firmicutes,25EM2@186801|Clostridia	186801|Clostridia	P	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_1546776_6	357808.RoseRS_0526	2.655e-25	115.0	2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi	200795|Chloroflexi	S	pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_1546776_1	686340.Metal_3486	2.437e-129	421.0	COG2132@1|root,COG2132@2|Bacteria,1R7BF@1224|Proteobacteria,1S0VI@1236|Gammaproteobacteria,1XG8R@135618|Methylococcales	135618|Methylococcales	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158535_k127_1546776_5	262724.TT_C1546	2.219e-54	196.0	COG0066@1|root,COG0066@2|Bacteria,1WIV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.114	ko:K16793	ko00300,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00680,map01100,map01120,map01130,map01210,map01230	M00433,M00608	R03444,R04371,R09720,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158535_k127_1546776_3	1123386.AUIW01000008_gene1912	7.354e-127	424.0	COG0065@1|root,COG0065@2|Bacteria,1WIHU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.114	ko:K16792	ko00300,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00680,map01100,map01120,map01130,map01210,map01230	M00433,M00608	R03444,R04371,R09720,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158535_k127_1546776_0	926550.CLDAP_04770	3.595e-149	487.0	COG0119@1|root,COG0119@2|Bacteria,2G5N1@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K01655	ko00300,ko00620,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R00271	RC00004,RC00067,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158535_k127_1546776_4	42256.RradSPS_2577	1.09e-113	380.0	COG2059@1|root,COG2059@2|Bacteria,2IB69@201174|Actinobacteria	201174|Actinobacteria	P	chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_1546776_8	1907.SGLAU_30880	4.737e-06	57.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
SRR25158535_k127_1546776_2	1128421.JAGA01000003_gene3258	3.58e-129	436.0	COG2303@1|root,COG2303@2|Bacteria,2NRUE@2323|unclassified Bacteria	2|Bacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRR25158535_k127_1566630_5	1265310.CCBD010000070_gene143	3.506e-16	83.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,233ZS@1762|Mycobacteriaceae	201174|Actinobacteria	C	4Fe-4S dicluster domain	hybA	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7
SRR25158535_k127_1566630_4	479434.Sthe_3390	4.776e-21	106.0	COG3301@1|root,COG3301@2|Bacteria,2GA0G@200795|Chloroflexi,27YBQ@189775|Thermomicrobia	189775|Thermomicrobia	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158535_k127_1566630_8	290397.Adeh_2086	2.286e-13	83.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,42VNJ@68525|delta/epsilon subdivisions,2WS9J@28221|Deltaproteobacteria,2Z2AD@29|Myxococcales	28221|Deltaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
SRR25158535_k127_1566630_6	1303518.CCALI_01828	5.025e-16	81.0	2CJPB@1|root,33JM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1566630_0	525904.Tter_1351	7.202e-101	342.0	COG0075@1|root,COG0075@2|Bacteria,2NP52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	dhsS	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.sll1559,iSB619.SA_RS08700	Aminotran_5
SRR25158535_k127_1566630_2	997346.HMPREF9374_0925	1.581e-69	242.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,27B18@186824|Thermoactinomycetaceae	91061|Bacilli	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158535_k127_1566630_7	1155714.KB891995_gene4161	1.121e-15	84.0	COG1051@1|root,COG1051@2|Bacteria,2IG0R@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158535_k127_1566630_3	365528.KB891181_gene4670	2.441e-27	117.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4ET6R@85013|Frankiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158535_k127_1566630_1	867903.ThesuDRAFT_02083	2.315e-92	307.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1579727_0	1121468.AUBR01000003_gene616	3.904e-167	550.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42EUK@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158535_k127_1579727_33	1382359.JIAL01000001_gene881	1.995e-18	100.0	COG0816@1|root,COG0816@2|Bacteria,3Y5AU@57723|Acidobacteria,2JJX3@204432|Acidobacteriia	204432|Acidobacteriia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158535_k127_1579727_13	926569.ANT_22320	1.403e-57	218.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158535_k127_1579727_43	479434.Sthe_2537	2.139e-07	57.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	chpR	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051259,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:0097351,GO:1901363	-	ko:K07172,ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
SRR25158535_k127_1579727_34	479434.Sthe_2536	6.565e-18	88.0	COG3654@1|root,COG3654@2|Bacteria,2G7HS@200795|Chloroflexi	200795|Chloroflexi	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158535_k127_1579727_11	1382306.JNIM01000001_gene1345	5.258e-65	227.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158535_k127_1579727_7	644966.Tmar_1171	3.326e-83	291.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WCHT@538999|Clostridiales incertae sedis	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158535_k127_1579727_46	596151.DesfrDRAFT_2049	5.371e-05	55.0	COG1722@1|root,COG1722@2|Bacteria,1PZUE@1224|Proteobacteria,43334@68525|delta/epsilon subdivisions,2WYAA@28221|Deltaproteobacteria,2MD2Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158535_k127_1579727_25	1382356.JQMP01000001_gene909	5.922e-27	122.0	COG0596@1|root,COG0596@2|Bacteria,2G8RV@200795|Chloroflexi,27Z4P@189775|Thermomicrobia	189775|Thermomicrobia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1579727_12	443143.GM18_2533	2.377e-60	218.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,43S7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158535_k127_1579727_17	1121468.AUBR01000002_gene652	5.382e-44	184.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,42FQN@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
SRR25158535_k127_1579727_8	292459.STH836	1.51e-80	291.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158535_k127_1579727_2	1382304.JNIL01000001_gene2887	6.848e-125	426.0	COG0213@1|root,COG0295@1|root,COG0213@2|Bacteria,COG0295@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,278UM@186823|Alicyclobacillaceae	91061|Bacilli	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158535_k127_1579727_20	1408422.JHYF01000001_gene2876	2.451e-34	152.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,36HB5@31979|Clostridiaceae	186801|Clostridia	S	peptidase	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158535_k127_1579727_47	709986.Deima_1455	0.0003642	52.0	COG2206@1|root,COG2206@2|Bacteria,1WNFB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158535_k127_1579727_30	1120985.AUMI01000020_gene1270	3.418e-23	112.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4H3XP@909932|Negativicutes	909932|Negativicutes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158535_k127_1579727_18	326427.Cagg_3848	8.463e-39	152.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158535_k127_1579727_14	429009.Adeg_1292	2.804e-57	215.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158535_k127_1579727_10	309801.trd_0438	4.098e-65	241.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi,27YEA@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158535_k127_1579727_21	1382356.JQMP01000003_gene2415	6.789e-33	144.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi,27Y83@189775|Thermomicrobia	189775|Thermomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158535_k127_1579727_9	429009.Adeg_1146	2.505e-68	242.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,42FFX@68295|Thermoanaerobacterales	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158535_k127_1579727_1	562970.Btus_1769	1.748e-132	448.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158535_k127_1579727_22	232348.ADXL01000079_gene982	1.833e-31	142.0	COG0344@1|root,COG0344@2|Bacteria,1G3HV@1117|Cyanobacteria,1GYXY@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158535_k127_1579727_6	1128421.JAGA01000002_gene607	3.05e-84	297.0	COG0240@1|root,COG0240@2|Bacteria,2NP1N@2323|unclassified Bacteria	2|Bacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158535_k127_1579727_38	404589.Anae109_0398	6.477e-11	76.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158535_k127_1579727_45	525909.Afer_0610	2.145e-06	55.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100,ko:K13280	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158535_k127_1579727_19	1121877.JQKF01000009_gene593	1.052e-36	145.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4CN73@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nickel-containing superoxide dismutase	sodN	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158535_k127_1579727_35	1303518.CCALI_00032	6.968e-15	78.0	COG2924@1|root,COG2924@2|Bacteria	2|Bacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158535_k127_1579727_5	861299.J421_0944	8.143e-88	297.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158535_k127_1579727_39	1463900.JOIX01000005_gene1224	2.066e-10	65.0	2EJC3@1|root,33D37@2|Bacteria,2GQN8@201174|Actinobacteria	201174|Actinobacteria	S	gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	GvpG
SRR25158535_k127_1579727_26	710686.Mycsm_05560	2.503e-24	119.0	2DM5J@1|root,31T6B@2|Bacteria,2GMP8@201174|Actinobacteria,2390N@1762|Mycobacteriaceae	201174|Actinobacteria	S	Gas vesicle synthesis protein GvpL/GvpF	gvpL2	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158535_k127_1579727_41	575540.Isop_0763	2.555e-08	59.0	2A5TH@1|root,30UIY@2|Bacteria,2J45H@203682|Planctomycetes	203682|Planctomycetes	S	Gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158535_k127_1579727_37	953739.SVEN_6857	1.513e-11	76.0	2DM5J@1|root,31T6B@2|Bacteria,2GMP8@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicle	gvpL2	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158535_k127_1579727_32	204669.Acid345_2406	4.153e-20	102.0	arCOG06390@1|root,330IR@2|Bacteria	2|Bacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle,GvpK
SRR25158535_k127_1579727_28	1046724.KB889840_gene64	1.055e-23	105.0	2E5BC@1|root,3303G@2|Bacteria,1N7VI@1224|Proteobacteria,1SRDR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158535_k127_1579727_24	204669.Acid345_2404	5.796e-27	112.0	arCOG03092@1|root,32YMQ@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158535_k127_1579727_4	204669.Acid345_2403	8.037e-101	353.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,3Y2RK@57723|Acidobacteria,2JHY1@204432|Acidobacteriia	204432|Acidobacteriia	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS
SRR25158535_k127_1579727_16	483219.LILAB_07755	4.078e-50	198.0	COG0697@1|root,COG2770@1|root,COG5002@1|root,COG0697@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,43C5I@68525|delta/epsilon subdivisions,2X7FT@28221|Deltaproteobacteria,2YZ70@29|Myxococcales	28221|Deltaproteobacteria	EGT	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1579727_29	1449063.JMLS01000005_gene3328	2.182e-23	115.0	COG2340@1|root,COG2340@2|Bacteria,1UY0N@1239|Firmicutes,4HD99@91061|Bacilli,26VYI@186822|Paenibacillaceae	91061|Bacilli	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
SRR25158535_k127_1579727_40	1034769.KB910518_gene1213	7.187e-09	68.0	COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,LRR_5,Laminin_G_3
SRR25158535_k127_1579727_44	1157490.EL26_03375	4.084e-07	53.0	COG1225@1|root,COG1225@2|Bacteria,1VGP9@1239|Firmicutes,4HQ3V@91061|Bacilli,27AF7@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_1579727_27	1051632.TPY_0742	3.928e-24	104.0	COG1225@1|root,COG1225@2|Bacteria,1UV64@1239|Firmicutes,24HTS@186801|Clostridia	186801|Clostridia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158535_k127_1579727_36	216816.GS08_00625	1.908e-14	86.0	COG1011@1|root,COG1011@2|Bacteria,2I2GN@201174|Actinobacteria,4CZF4@85004|Bifidobacteriales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158535_k127_1579727_15	319003.Bra1253DRAFT_00014	4.23e-54	199.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
SRR25158535_k127_1579727_3	1128421.JAGA01000002_gene392	5.786e-107	379.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158535_k127_1579727_23	644283.Micau_4456	2.979e-30	136.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4DBBD@85008|Micromonosporales	201174|Actinobacteria	S	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158535_k127_1579727_31	926560.KE387023_gene2631	5.383e-22	110.0	2EH2B@1|root,33AU9@2|Bacteria,1WMY7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158535_k127_1579727_42	1121106.JQKB01000020_gene2001	2.61e-08	64.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	MA20_24210	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158535_k127_160460_3	290397.Adeh_3709	2.385e-42	158.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_160460_1	469371.Tbis_0818	8.43e-88	310.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4E1FF@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR25158535_k127_160460_7	1335760.ASTG01000003_gene1586	7.422e-06	59.0	29W6E@1|root,30HRH@2|Bacteria,1N13Y@1224|Proteobacteria,2VEK5@28211|Alphaproteobacteria,2K81M@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158535_k127_160460_0	35754.JNYJ01000005_gene5498	3.362e-160	528.0	COG2304@1|root,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4D9P9@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial extracellular solute-binding protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR25158535_k127_160460_5	35754.JNYJ01000005_gene5499	6.834e-09	68.0	2FIZ9@1|root,34AQ2@2|Bacteria,2INWA@201174|Actinobacteria,4DIXT@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_160460_2	479432.Sros_1511	4.639e-52	193.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158535_k127_160460_4	1347369.CCAD010000080_gene3151	2.185e-38	161.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,4HGVU@91061|Bacilli,1ZQYT@1386|Bacillus	91061|Bacilli	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158535_k127_160460_6	326427.Cagg_2302	7.474e-08	66.0	2DE6H@1|root,2ZKPY@2|Bacteria,2G9I8@200795|Chloroflexi,377JX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_167316_13	574087.Acear_0086	6.006e-48	190.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,2482F@186801|Clostridia,3WBRM@53433|Halanaerobiales	186801|Clostridia	Q	PFAM D-aminoacylase	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158535_k127_167316_16	926550.CLDAP_37980	1.906e-37	152.0	COG0500@1|root,COG1819@1|root,COG1819@2|Bacteria,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_167316_9	671143.DAMO_1458	6.763e-93	323.0	COG1473@1|root,COG1473@2|Bacteria,2NP7P@2323|unclassified Bacteria	2|Bacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_167316_12	1047013.AQSP01000140_gene2513	2.359e-51	196.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158535_k127_167316_15	1303518.CCALI_01089	2.056e-41	171.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_167316_0	671143.DAMO_2896	3.296e-214	717.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_167316_4	198467.NP92_06670	2.331e-132	436.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,21W8W@150247|Anoxybacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158535_k127_167316_8	401526.TcarDRAFT_0013	1.877e-99	347.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4H3I7@909932|Negativicutes	909932|Negativicutes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158535_k127_167316_2	479434.Sthe_1974	2.854e-153	509.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158535_k127_167316_19	1125863.JAFN01000001_gene1797	1.418e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_167316_5	1128421.JAGA01000002_gene1380	2.115e-124	429.0	COG1921@1|root,COG1921@2|Bacteria,2NNT6@2323|unclassified Bacteria	2|Bacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006	Se-cys_synth_N,SelA
SRR25158535_k127_167316_17	1128421.JAGA01000004_gene2533	6.774e-37	156.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DUF389
SRR25158535_k127_167316_22	635013.TherJR_2998	5.821e-23	104.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,2633R@186807|Peptococcaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158535_k127_167316_14	1150399.AQYK01000002_gene3209	8.39e-47	188.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
SRR25158535_k127_167316_1	1463821.JOGR01000017_gene677	1.856e-157	517.0	COG0174@1|root,COG0174@2|Bacteria,2GKU9@201174|Actinobacteria	201174|Actinobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158535_k127_167316_11	251221.35214018	1.162e-58	226.0	COG1162@1|root,COG1162@2|Bacteria,1G18W@1117|Cyanobacteria	1117|Cyanobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158535_k127_167316_7	1306174.JODP01000032_gene4027	3.193e-100	349.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158535_k127_167316_21	926569.ANT_02430	6.827e-24	113.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_167316_26	345341.KUTG_02467	3.654e-10	71.0	COG3087@1|root,COG3087@2|Bacteria,2IS4S@201174|Actinobacteria,4EC1E@85010|Pseudonocardiales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_167316_24	768710.DesyoDRAFT_0973	5.702e-18	93.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,262YN@186807|Peptococcaceae	186801|Clostridia	KT	Stress-responsive transcriptional regulator	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158535_k127_167316_23	357808.RoseRS_1471	1.028e-21	106.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_167316_27	290397.Adeh_1087	1.146e-08	65.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2YW4H@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158535_k127_167316_25	1187848.AJYQ01000011_gene3045	6.256e-12	69.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XTKT@135623|Vibrionales	135623|Vibrionales	S	Integral membrane protein	yggT	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158535_k127_167316_10	1435356.Y013_15455	9.711e-77	266.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4FUZI@85025|Nocardiaceae	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158535_k127_167316_20	1444770.AF72_08175	1.815e-24	115.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1X37Z@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate	gph	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158535_k127_167316_18	637389.Acaty_c0590	9.523e-37	147.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,2NCVZ@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158535_k127_167316_28	649638.Trad_2746	0.0001485	52.0	COG4694@1|root,COG4694@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
SRR25158535_k127_167316_3	635013.TherJR_2152	6.245e-141	457.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158535_k127_167316_6	1382306.JNIM01000001_gene41	3.168e-115	383.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158535_k127_1703871_5	316274.Haur_2283	1.383e-27	121.0	COG3879@1|root,COG3879@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158535_k127_1703871_7	1265310.CCBD010000064_gene993	6.481e-18	97.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,233T1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158535_k127_1703871_6	326427.Cagg_1012	1.328e-23	109.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi,37629@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
SRR25158535_k127_1703871_4	1173022.Cri9333_0192	5.433e-37	158.0	COG0477@1|root,COG2814@2|Bacteria,1G02H@1117|Cyanobacteria,1H9WW@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Arabinose efflux permease	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1703871_1	926566.Terro_2657	5.099e-163	533.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1703871_0	525904.Tter_1201	2.961e-185	625.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1703871_2	309799.DICTH_1684	4.741e-79	290.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158535_k127_1737523_1	1382356.JQMP01000003_gene1710	5.049e-83	285.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158535_k127_1737523_5	255470.cbdbA1186	4.889e-07	54.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi,34DI9@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158535_k127_1737523_2	266117.Rxyl_1369	9.129e-70	265.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158535_k127_1737523_4	485916.Dtox_0161	2.526e-08	63.0	2EG4K@1|root,339WK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1737523_0	309801.trd_0084	8.783e-171	562.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158535_k127_1737523_3	1449355.JQNR01000005_gene3382	8.654e-38	151.0	COG2267@1|root,COG2267@2|Bacteria,2H83P@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_1798851_2	156889.Mmc1_1619	6.356e-09	57.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_1798851_0	1396858.Q666_02545	5.171e-67	256.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,4644B@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG4962 Flp pilus assembly protein, ATPase CpaF	tadA	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158535_k127_1798851_3	309801.trd_1013	1.771e-05	57.0	COG3745@1|root,COG3745@2|Bacteria,2G7H3@200795|Chloroflexi,27XF4@189775|Thermomicrobia	189775|Thermomicrobia	U	SAF	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158535_k127_1798851_1	926569.ANT_08580	9.145e-50	200.0	COG2199@1|root,COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3850@2|Bacteria,2G87Y@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HisKA_7TM,PAS_4,PAS_8
SRR25158535_k127_1803138_1	521674.Plim_4031	1.216e-186	594.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
SRR25158535_k127_1803138_7	861299.J421_2024	2.387e-48	200.0	COG0665@1|root,COG0665@2|Bacteria,1ZSS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_1803138_2	404589.Anae109_2417	6.614e-164	546.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
SRR25158535_k127_1803138_0	1254432.SCE1572_07890	5.814e-245	767.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158535_k127_1803138_4	1267005.KB911257_gene874	1.312e-149	492.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158535_k127_1803138_3	118163.Ple7327_2051	5.757e-162	522.0	COG4664@1|root,COG4664@2|Bacteria,1G1UX@1117|Cyanobacteria,3VJCW@52604|Pleurocapsales	2|Bacteria	Q	TIGRFAM TRAP transporter, DctM subunit	dctM	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158535_k127_1803138_6	118163.Ple7327_2052	2.902e-59	212.0	COG4665@1|root,COG4665@2|Bacteria	2|Bacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
SRR25158535_k127_1803138_5	118163.Ple7327_2053	9.334e-116	381.0	COG4663@1|root,COG4663@2|Bacteria,1G1BA@1117|Cyanobacteria,3VHWR@52604|Pleurocapsales	1117|Cyanobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158535_k127_1866745_2	645991.Sgly_1744	8.835e-46	171.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,261NH@186807|Peptococcaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158535_k127_1866745_1	1123511.KB905862_gene2394	8.246e-77	264.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H2ZZ@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158535_k127_1866745_0	1033743.CAES01000011_gene4454	1.836e-104	371.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158535_k127_1866745_3	1121377.KB906406_gene168	3.772e-13	77.0	COG1408@1|root,COG1408@2|Bacteria,1WJWG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_1887088_47	1193181.BN10_1300016	5.23e-14	77.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_23	1382356.JQMP01000003_gene2082	1.901e-73	253.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158535_k127_1887088_42	324602.Caur_0522	1.043e-23	105.0	COG0718@1|root,COG0718@2|Bacteria,2G77S@200795|Chloroflexi,375X5@32061|Chloroflexia	32061|Chloroflexia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158535_k127_1887088_16	370438.PTH_0051	5.07e-99	344.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,2602Z@186807|Peptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158535_k127_1887088_46	479434.Sthe_1216	1.561e-15	82.0	COG1917@1|root,COG1917@2|Bacteria,2G6MV@200795|Chloroflexi,27ZCJ@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1887088_26	324602.Caur_2883	1.982e-64	228.0	COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia	32061|Chloroflexia	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158535_k127_1887088_10	926560.KE387023_gene3499	8.791e-120	397.0	COG2271@1|root,COG2271@2|Bacteria,1WNIE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1887088_9	357808.RoseRS_1830	5.579e-141	455.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi,376YA@32061|Chloroflexia	32061|Chloroflexia	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158535_k127_1887088_39	861299.J421_3139	1.269e-37	164.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158535_k127_1887088_31	1297865.APJD01000012_gene1322	4.349e-60	231.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,3JRHZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158535_k127_1887088_30	1380390.JIAT01000010_gene3347	4.161e-62	239.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CSXI@84995|Rubrobacteria	84995|Rubrobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_1887088_28	1345697.M493_07610	8.747e-63	240.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1WGK7@129337|Geobacillus	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158535_k127_1887088_21	1469245.JFBG01000012_gene917	6.544e-77	267.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1SZ2D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158535_k127_1887088_20	1345697.M493_07600	4.89e-82	290.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,1WF4B@129337|Geobacillus	91061|Bacilli	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_1887088_53	134676.ACPL_5056	3.288e-06	57.0	COG5164@1|root,COG5164@2|Bacteria	2|Bacteria	K	cell wall organization	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Collagen,Gram_pos_anchor,Laminin_G_3
SRR25158535_k127_1887088_7	562970.Btus_1243	6.42e-154	496.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_1887088_25	644966.Tmar_2131	9.304e-65	230.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158535_k127_1887088_18	926550.CLDAP_07100	6.033e-88	302.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_1887088_44	1463895.JODA01000033_gene3039	5.078e-23	109.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_1887088_36	1120949.KB903303_gene6761	4.762e-50	200.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4D8MM@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_1887088_40	644282.Deba_0922	1.656e-32	145.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,42R8W@68525|delta/epsilon subdivisions,2WMZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_1887088_22	485913.Krac_9068	2.548e-74	262.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158535_k127_1887088_19	290397.Adeh_0051	1.1e-82	281.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158535_k127_1887088_0	479434.Sthe_2025	3.361e-285	887.0	COG0365@1|root,COG0365@2|Bacteria,2G83G@200795|Chloroflexi,27XZN@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158535_k127_1887088_4	767817.Desgi_1433	3.158e-166	563.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1887088_2	767817.Desgi_1433	7.604e-177	569.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1887088_49	215803.DB30_5048	3.126e-09	70.0	2AVTK@1|root,31MM6@2|Bacteria,1QJFF@1224|Proteobacteria,434US@68525|delta/epsilon subdivisions,2X913@28221|Deltaproteobacteria,2Z1E2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_15	1382306.JNIM01000001_gene331	3.328e-101	335.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158535_k127_1887088_11	1382306.JNIM01000001_gene332	2.112e-119	390.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158535_k127_1887088_24	266117.Rxyl_1748	1.412e-65	239.0	COG1024@1|root,COG1024@2|Bacteria,2GNXD@201174|Actinobacteria,4CQCF@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158535_k127_1887088_6	266117.Rxyl_1760	2.519e-159	520.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW6@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_1887088_37	926550.CLDAP_31690	5.649e-45	179.0	COG1028@1|root,COG1028@2|Bacteria,2G8KA@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_1887088_38	416348.Hlac_2304	4.858e-41	169.0	COG0520@1|root,arCOG00065@2157|Archaea,2XU9W@28890|Euryarchaeota,23SK6@183963|Halobacteria	183963|Halobacteria	E	COG0520 Selenocysteine lyase	sufS2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158535_k127_1887088_48	1128421.JAGA01000003_gene3190	1.57e-10	67.0	2EM6G@1|root,33EVQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_34	35754.JNYJ01000037_gene4671	2.484e-51	205.0	COG3055@1|root,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4DFPE@85008|Micromonosporales	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
SRR25158535_k127_1887088_50	634498.mru_0372	8.937e-08	64.0	COG0730@1|root,arCOG02050@2157|Archaea,2XXQV@28890|Euryarchaeota,23PE9@183925|Methanobacteria	183925|Methanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158535_k127_1887088_55	1118054.CAGW01000074_gene872	0.0001941	51.0	2DZXU@1|root,32VMR@2|Bacteria,1VBBV@1239|Firmicutes,4HPWN@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_45	1183438.GKIL_2486	7.711e-22	104.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_33	1382356.JQMP01000003_gene2027	1.028e-51	192.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_1887088_17	525904.Tter_0886	1.139e-97	341.0	COG0179@1|root,COG0179@2|Bacteria,2NP4G@2323|unclassified Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158535_k127_1887088_35	882086.SacxiDRAFT_2015	8.633e-51	203.0	COG2301@1|root,COG2301@2|Bacteria,2GN8S@201174|Actinobacteria,4EC6K@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158535_k127_1887088_5	479434.Sthe_1794	7.276e-163	529.0	COG1960@1|root,COG1960@2|Bacteria,2G815@200795|Chloroflexi,27Z4U@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_1887088_32	1101188.KI912156_gene4127	1.401e-59	210.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,1W93S@1268|Micrococcaceae	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
SRR25158535_k127_1887088_51	1380358.JADJ01000018_gene2509	1.532e-07	61.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,1XJCN@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1887088_52	479434.Sthe_3010	3.3e-07	57.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158535_k127_1887088_1	1123024.AUII01000002_gene1150	4.359e-244	763.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4E0IR@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158535_k127_1887088_12	1429046.RR21198_2582	3.517e-116	384.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4FUIQ@85025|Nocardiaceae	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158535_k127_1887088_41	234267.Acid_7472	4.651e-31	136.0	COG1917@1|root,COG1917@2|Bacteria,3Y596@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1887088_13	1163398.AJJP01000043_gene2340	6.189e-107	367.0	COG1234@1|root,COG2333@1|root,COG1234@2|Bacteria,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria	1224|Proteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_1887088_3	1297569.MESS2_770013	4.18e-176	569.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1887088_27	765910.MARPU_10060	7.131e-64	227.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1WY5H@135613|Chromatiales	135613|Chromatiales	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_1887088_8	331869.BAL199_29475	3.914e-149	505.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4BP9X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	MA20_30205	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158535_k127_1887088_29	1211815.CBYP010000007_gene322	1.173e-62	235.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4EV9F@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_1887088_14	1156844.KB891809_gene7877	4.458e-106	366.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria	201174|Actinobacteria	E	Hydroxymethylglutaryl-CoA lyase	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158535_k127_1887088_56	1123368.AUIS01000004_gene272	0.0008754	49.0	COG3663@1|root,COG3663@2|Bacteria,1RAVZ@1224|Proteobacteria,1S2GN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158535_k127_1921589_1	266117.Rxyl_0923	2.848e-125	413.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria,4CQFE@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158535_k127_1921589_5	696747.NIES39_M00330	2.318e-21	98.0	COG0664@1|root,COG0664@2|Bacteria,1G57E@1117|Cyanobacteria,1HAIX@1150|Oscillatoriales	1117|Cyanobacteria	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_1921589_2	404589.Anae109_2517	4.071e-104	351.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
SRR25158535_k127_1921589_3	1123023.JIAI01000006_gene225	5.253e-81	286.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DYFJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158535_k127_1921589_0	485916.Dtox_0988	4.079e-140	459.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,2607H@186807|Peptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_1921589_4	1382306.JNIM01000001_gene536	2.903e-60	233.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158535_k127_1950131_2	266117.Rxyl_0070	3.866e-113	407.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158535_k127_1950131_9	1234364.AMSF01000087_gene2795	1.3e-53	201.0	COG0586@1|root,COG0586@2|Bacteria,1RGII@1224|Proteobacteria,1S844@1236|Gammaproteobacteria,1XCVR@135614|Xanthomonadales	135614|Xanthomonadales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158535_k127_1950131_5	909663.KI867151_gene3008	4.212e-93	321.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158535_k127_1950131_0	1120973.AQXL01000111_gene924	5.076e-163	537.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,2799W@186823|Alicyclobacillaceae	91061|Bacilli	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158535_k127_1950131_8	926550.CLDAP_06960	2.102e-68	263.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1950131_1	1128421.JAGA01000003_gene2709	1.402e-149	494.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
SRR25158535_k127_1950131_6	479434.Sthe_0699	1.885e-85	304.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158535_k127_1950131_14	504728.K649_07695	2.191e-20	107.0	COG0477@1|root,COG2814@2|Bacteria,1WJAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
SRR25158535_k127_1950131_3	1380390.JIAT01000010_gene3850	4.776e-98	333.0	COG2114@1|root,COG2114@2|Bacteria,2HSA4@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	cya	GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158535_k127_1950131_15	1173025.GEI7407_1649	8.253e-07	62.0	2CEMI@1|root,331MB@2|Bacteria,1G8M0@1117|Cyanobacteria,1HDYV@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1950131_7	1268622.AVS7_04564	1.903e-71	258.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,4ABW8@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158535_k127_1950131_11	1324957.K933_03450	4.781e-35	153.0	COG1893@1|root,arCOG04139@2157|Archaea,2XTBD@28890|Euryarchaeota,23T98@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158535_k127_1950131_4	207559.Dde_1500	1.015e-93	316.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2M8WY@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158535_k127_1950131_12	1123401.JHYQ01000045_gene3372	1.198e-34	135.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158535_k127_1950131_10	1394178.AWOO02000002_gene1596	1.375e-35	143.0	COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4EPJ6@85012|Streptosporangiales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158535_k127_1950131_13	1077972.ARGLB_085_01520	1.702e-29	126.0	2BVXR@1|root,32IG2@2|Bacteria,2IMT1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158535_k127_195047_7	1869.MB27_26275	2.205e-62	219.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4D8MM@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_195047_3	1146883.BLASA_2766	3.72e-103	351.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EUD7@85013|Frankiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_195047_27	1197706.AKKK01000062_gene1708	1.433e-05	52.0	2BKAB@1|root,32EQK@2|Bacteria,2GXJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_195047_30	391625.PPSIR1_23474	2.59e-05	53.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158535_k127_195047_21	543632.JOJL01000013_gene9310	5.569e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,2IN4T@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_195047_15	1110697.NCAST_11_00360	1.948e-29	123.0	COG1846@1|root,COG1846@2|Bacteria,2INEU@201174|Actinobacteria,4G22G@85025|Nocardiaceae	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
SRR25158535_k127_195047_20	405948.SACE_4576	8.872e-24	107.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria,4E72Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_195047_14	1370120.AUWR01000008_gene456	1.472e-30	133.0	COG2128@1|root,COG2128@2|Bacteria,2ICVV@201174|Actinobacteria,236U4@1762|Mycobacteriaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_195047_23	591158.SSMG_00907	2.202e-10	66.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_195047_5	290397.Adeh_1010	4.736e-73	259.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,42SE7@68525|delta/epsilon subdivisions,2WPK7@28221|Deltaproteobacteria,2YVBX@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_195047_13	1121272.KB903291_gene3329	1.917e-31	136.0	2BKAB@1|root,32EQK@2|Bacteria,2GXJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_195047_29	1121377.KB906417_gene3859	2.278e-05	56.0	2950P@1|root,2ZSDF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_195047_16	298655.KI912266_gene3232	4.496e-28	127.0	COG0748@1|root,COG0748@2|Bacteria,2HU2M@201174|Actinobacteria,4EWNH@85013|Frankiales	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_195047_10	266117.Rxyl_3190	4.648e-46	174.0	COG1309@1|root,COG1309@2|Bacteria,2IKK0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_195047_8	526227.Mesil_1024	1.187e-51	186.0	COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158535_k127_195047_4	42256.RradSPS_0363	2.628e-78	295.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CRP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
SRR25158535_k127_195047_2	1386089.N865_04610	6.296e-228	713.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria,4FIY8@85021|Intrasporangiaceae	201174|Actinobacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158535_k127_195047_28	55952.BU52_08185	2.049e-05	55.0	COG2267@1|root,COG2267@2|Bacteria,2GMBV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_195047_6	331869.BAL199_06519	2.911e-72	253.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,4BT86@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158535_k127_195047_26	404589.Anae109_3189	5.968e-07	56.0	COG3668@1|root,33GBB@2|Bacteria,1R03G@1224|Proteobacteria	1224|Proteobacteria	S	negative regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_195047_12	68260.JOAY01000003_gene4553	6.025e-38	149.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158535_k127_195047_18	945713.IALB_0305	6.838e-28	117.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158535_k127_195047_31	498848.TaqDRAFT_3933	0.0003288	50.0	2EAPD@1|root,334RU@2|Bacteria,1WJVX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158535_k127_195047_0	525904.Tter_0881	1.291e-315	986.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158535_k127_195047_17	309801.trd_1112	6.076e-28	116.0	COG4327@1|root,COG4327@2|Bacteria,2G9BG@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
SRR25158535_k127_195047_1	309801.trd_1113	1.221e-281	878.0	COG4147@1|root,COG4147@2|Bacteria,2G6M1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158535_k127_195047_9	1128421.JAGA01000002_gene1188	3.633e-46	177.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158535_k127_195047_11	1128421.JAGA01000002_gene1189	4.922e-46	171.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1982621_0	289376.THEYE_A0554	3.662e-162	529.0	COG0480@1|root,COG0480@2|Bacteria,3J0WU@40117|Nitrospirae	40117|Nitrospirae	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158535_k127_1982621_4	305700.B447_20690	5.049e-18	91.0	COG1708@1|root,COG3398@1|root,COG1708@2|Bacteria,COG3398@2|Bacteria,1RCAH@1224|Proteobacteria,2VQYD@28216|Betaproteobacteria,2KXYD@206389|Rhodocyclales	206389|Rhodocyclales	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1982621_3	479434.Sthe_1654	1.434e-81	300.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi,27Y53@189775|Thermomicrobia	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_1982621_6	314271.RB2654_16076	3.001e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	MA20_42300	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158535_k127_1982621_2	243164.DET0601	1.784e-114	381.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,34D17@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158535_k127_1982621_1	926550.CLDAP_37440	1.578e-119	415.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158535_k127_1982621_5	29306.JOBE01000032_gene5878	3.791e-12	76.0	COG1051@1|root,COG1051@2|Bacteria,2IK42@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	ATP_bind_2,NUDIX
SRR25158535_k127_1989342_24	1125971.ASJB01000097_gene653	4.881e-14	75.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,CHASE2,GGDEF
SRR25158535_k127_1989342_27	926690.KE386573_gene1478	3.044e-12	74.0	arCOG01588@1|root,arCOG01588@2157|Archaea,2XZWS@28890|Euryarchaeota,23XIE@183963|Halobacteria	183963|Halobacteria	E	lysine biosynthesis protein LysW	argW	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158535_k127_1989342_4	383372.Rcas_3469	4.382e-117	385.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,374VK@32061|Chloroflexia	32061|Chloroflexia	HJ	PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
SRR25158535_k127_1989342_3	357808.RoseRS_1060	1.72e-124	422.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,374YZ@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
SRR25158535_k127_1989342_12	1128421.JAGA01000001_gene2381	6.543e-66	243.0	COG0548@1|root,COG0548@2|Bacteria,2NPGD@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8,3.5.1.16	ko:K00930,ko:K01438,ko:K05828,ko:K05831	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R00669,R02649,R09107,R09776,R09779,R10930,R10933	RC00002,RC00043,RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Peptidase_M20
SRR25158535_k127_1989342_2	926569.ANT_12380	1.229e-132	435.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
SRR25158535_k127_1989342_5	649638.Trad_1404	2.738e-86	304.0	COG0624@1|root,COG0624@2|Bacteria,1WIXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
SRR25158535_k127_1989342_10	649747.HMPREF0083_06230	3.468e-70	263.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae	91061|Bacilli	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158535_k127_1989342_19	1242864.D187_000778	7.645e-29	135.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
SRR25158535_k127_1989342_6	880073.Calab_2862	1.492e-84	301.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,PAS_3,Response_reg,dCache_2
SRR25158535_k127_1989342_14	326427.Cagg_2296	7.524e-62	223.0	COG1235@1|root,COG1235@2|Bacteria,2G833@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158535_k127_1989342_8	1297742.A176_06712	7.576e-75	264.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158535_k127_1989342_25	1128421.JAGA01000001_gene2423	6.621e-13	79.0	2DC64@1|root,2ZD1F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1989342_18	477641.MODMU_2718	1.565e-29	129.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158535_k127_1989342_20	1869.MB27_07585	2.279e-26	113.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria,4DFX8@85008|Micromonosporales	201174|Actinobacteria	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
SRR25158535_k127_1989342_22	469381.Dpep_1065	4.961e-21	98.0	COG0647@1|root,COG0647@2|Bacteria,3TC1F@508458|Synergistetes	508458|Synergistetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
SRR25158535_k127_1989342_17	1267535.KB906767_gene4614	3.346e-41	173.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,3Y2SH@57723|Acidobacteria,2JHUE@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158535_k127_1989342_16	1094715.CM001373_gene1584	3.439e-53	207.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1JDZ1@118969|Legionellales	118969|Legionellales	L	ATP dependent DNA ligase C terminal region	ykoU	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_1989342_11	1463854.JOHT01000009_gene1508	1.884e-66	246.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_1989342_13	743719.PaelaDRAFT_3587	7.979e-64	238.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,26RNE@186822|Paenibacillaceae	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158535_k127_1989342_9	316274.Haur_4136	6.667e-72	255.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi,37610@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_1989342_21	1487953.JMKF01000065_gene4604	3.03e-22	111.0	COG0745@1|root,COG0745@2|Bacteria,1G42G@1117|Cyanobacteria,1H9FQ@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1989342_23	1125863.JAFN01000001_gene3175	2.95e-17	97.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42QVB@68525|delta/epsilon subdivisions,2WN5E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158535_k127_1989342_15	485913.Krac_8323	4.513e-55	221.0	COG5002@1|root,COG5002@2|Bacteria,2G8WY@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SRR25158535_k127_1989342_29	373994.Riv7116_3018	1.226e-05	51.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1HKPC@1161|Nostocales	1117|Cyanobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
SRR25158535_k127_1989342_7	1232410.KI421421_gene3645	1.657e-83	282.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,43S5T@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Clp protease	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158535_k127_1989342_1	1089548.KI783301_gene1937	1.112e-178	580.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3WEH5@539002|Bacillales incertae sedis	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158535_k127_1989342_28	518766.Rmar_2731	2.576e-09	62.0	COG1917@1|root,COG1917@2|Bacteria,4P9GY@976|Bacteroidetes,1FKCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1989342_0	479434.Sthe_1612	1.143e-242	779.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,27Y20@189775|Thermomicrobia	189775|Thermomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158535_k127_1989342_26	485913.Krac_5768	8.038e-13	80.0	COG0412@1|root,COG0412@2|Bacteria,2G8GH@200795|Chloroflexi	200795|Chloroflexi	Q	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_202077_4	326427.Cagg_0631	5.577e-17	83.0	COG0737@1|root,COG0737@2|Bacteria,2G7FX@200795|Chloroflexi,3764K@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos,TAT_signal
SRR25158535_k127_202077_2	469383.Cwoe_4057	1.064e-55	204.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4CT0C@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158535_k127_202077_1	1382306.JNIM01000001_gene993	1.88e-73	252.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158535_k127_202077_0	1382306.JNIM01000001_gene451	1.452e-135	445.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SRR25158535_k127_202077_3	1382306.JNIM01000001_gene994	6.309e-18	88.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	echF	-	1.6.5.3	ko:K00338,ko:K14091	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_10,Fer4_7
SRR25158535_k127_2089013_18	926550.CLDAP_37980	2.399e-17	87.0	COG0500@1|root,COG1819@1|root,COG1819@2|Bacteria,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_2089013_1	1499967.BAYZ01000028_gene1366	5.049e-154	509.0	COG3653@1|root,COG3653@2|Bacteria,2NNQ0@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	dan	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158535_k127_2089013_4	1379270.AUXF01000004_gene3060	1.689e-83	290.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRR25158535_k127_2089013_5	1242864.D187_000069	1.114e-70	261.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_2089013_20	762948.HMPREF0733_11401	4.21e-10	73.0	COG4478@1|root,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,1W8XP@1268|Micrococcaceae	201174|Actinobacteria	D	TIGRFAM integral membrane protein TIGR01906	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
SRR25158535_k127_2089013_8	1278073.MYSTI_02250	3.068e-56	201.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WQUD@28221|Deltaproteobacteria,2YVF3@29|Myxococcales	28221|Deltaproteobacteria	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_2089013_14	316274.Haur_4612	3.587e-33	143.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158535_k127_2089013_7	555079.Toce_2196	1.468e-60	231.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,42ERA@68295|Thermoanaerobacterales	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158535_k127_2089013_2	309801.trd_1799	1.661e-103	361.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158535_k127_2089013_23	204669.Acid345_3597	0.0009107	52.0	COG4319@1|root,COG4319@2|Bacteria,3Y89C@57723|Acidobacteria,2JNBD@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158535_k127_2089013_12	1382306.JNIM01000001_gene4052	3.715e-35	150.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158535_k127_2089013_21	1122604.JONR01000045_gene2505	1.885e-09	69.0	COG5513@1|root,COG5513@2|Bacteria,1Q83Y@1224|Proteobacteria,1TAXG@1236|Gammaproteobacteria,1X93Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Chagasin family peptidase inhibitor I42	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I42
SRR25158535_k127_2089013_11	498761.HM1_0174	9.935e-43	174.0	COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,24BJE@186801|Clostridia	186801|Clostridia	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	glnP2	-	-	ko:K09971,ko:K10040	ko02010,map02010	M00228,M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158535_k127_2089013_9	649747.HMPREF0083_02877	1.024e-55	203.0	COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,26U8V@186822|Paenibacillaceae	91061|Bacilli	P	Glutamine ABC transporter permease	glnM	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K10040	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158535_k127_2089013_6	298655.KI912266_gene3104	4.68e-62	224.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4ESNV@85013|Frankiales	201174|Actinobacteria	ET	PFAM Extracellular solute-binding protein, family 3	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
SRR25158535_k127_2089013_3	1501230.ET33_18605	1.222e-94	329.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,26QWX@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter	glnQ	-	-	ko:K10041	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158535_k127_2089013_13	1121271.AUCM01000003_gene1707	2.165e-33	146.0	COG2367@1|root,COG2367@2|Bacteria,1N9HE@1224|Proteobacteria,2UN6B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158535_k127_2089013_10	401526.TcarDRAFT_0930	4.689e-48	189.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H3GM@909932|Negativicutes	909932|Negativicutes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158535_k127_2089013_0	479434.Sthe_0777	1.208e-225	716.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRR25158535_k127_2089013_17	469371.Tbis_3287	3.926e-20	100.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158535_k127_2089013_16	1380390.JIAT01000010_gene3746	4.174e-25	122.0	COG1716@1|root,COG1994@1|root,COG1716@2|Bacteria,COG1994@2|Bacteria,2HFEF@201174|Actinobacteria,4CTVF@84995|Rubrobacteria	84995|Rubrobacteria	T	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2089013_22	1120705.FG95_01608	3.291e-08	67.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QUPD@1224|Proteobacteria,2TW3N@28211|Alphaproteobacteria,2K28S@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_2,Pyr_redox_3,cNMP_binding
SRR25158535_k127_2089013_15	379066.GAU_2556	2.252e-32	147.0	COG0189@1|root,COG0189@2|Bacteria,1ZU94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	HJ	Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
SRR25158535_k127_2090845_13	1382356.JQMP01000001_gene1263	2.362e-75	260.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_2090845_30	1382306.JNIM01000001_gene1642	3.308e-33	134.0	COG1051@1|root,COG1051@2|Bacteria,2G8SP@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_2090845_6	469383.Cwoe_5866	7.013e-109	369.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158535_k127_2090845_43	1122929.KB908229_gene3432	5.468e-15	84.0	COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2TS4X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158535_k127_2090845_33	1133850.SHJG_2523	6.167e-28	129.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria	201174|Actinobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_2090845_3	243231.GSU1677	4.588e-149	508.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158535_k127_2090845_11	525904.Tter_0353	7.81e-78	277.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158535_k127_2090845_45	926550.CLDAP_09590	5.927e-12	74.0	COG1262@1|root,COG4995@1|root,COG1262@2|Bacteria,COG4995@2|Bacteria,2G903@200795|Chloroflexi	200795|Chloroflexi	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158535_k127_2090845_31	1278073.MYSTI_07808	2.494e-31	145.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,42N55@68525|delta/epsilon subdivisions,2WVAY@28221|Deltaproteobacteria,2YWI6@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_2090845_0	671143.DAMO_2604	1.457e-191	614.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_2090845_23	670487.Ocepr_0305	1.357e-50	196.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158535_k127_2090845_47	530564.Psta_2340	4.152e-09	67.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2090845_2	526227.Mesil_1001	2.449e-158	520.0	COG1132@1|root,COG1132@2|Bacteria,1WMBB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_2090845_44	671143.DAMO_2398	4.274e-12	74.0	2CP7W@1|root,32MRP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2090845_32	235909.GK0964	7.238e-29	127.0	COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1WG1C@129337|Geobacillus	91061|Bacilli	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
SRR25158535_k127_2090845_1	479434.Sthe_1950	5.506e-185	600.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2090845_9	1382356.JQMP01000003_gene1978	7.907e-93	326.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158535_k127_2090845_46	794846.AJQU01000035_gene3940	6.66e-10	63.0	COG2128@1|root,COG2128@2|Bacteria,1RAJ4@1224|Proteobacteria,2U652@28211|Alphaproteobacteria,4BCA0@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_2090845_20	1459636.NTE_03328	3.123e-55	209.0	COG1741@1|root,arCOG02935@2157|Archaea	2157|Archaea	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158535_k127_2090845_24	861299.J421_0860	6.588e-42	160.0	COG2353@1|root,COG2353@2|Bacteria,1ZV1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158535_k127_2090845_34	1123024.AUII01000003_gene3371	9.478e-28	117.0	COG1846@1|root,COG1846@2|Bacteria,2INRY@201174|Actinobacteria,4EEQ9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_2090845_16	1197130.BAFM01000030_gene3135	2.895e-64	243.0	COG1472@1|root,arCOG04634@2157|Archaea,2XTGV@28890|Euryarchaeota,23TKJ@183963|Halobacteria	183963|Halobacteria	G	COG1472 Beta-glucosidase-related glycosidases	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158535_k127_2090845_8	1341151.ASZU01000003_gene2602	2.565e-93	343.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,27CNY@186824|Thermoactinomycetaceae	91061|Bacilli	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158535_k127_2090845_22	321332.CYB_0331	4.119e-52	209.0	COG1680@1|root,COG1680@2|Bacteria,1GJJ7@1117|Cyanobacteria,1H2CY@1129|Synechococcus	1117|Cyanobacteria	V	hmm pf00144	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_2090845_14	401053.AciPR4_1105	6.367e-71	253.0	COG2377@1|root,COG2377@2|Bacteria,3Y3CU@57723|Acidobacteria,2JI1E@204432|Acidobacteriia	204432|Acidobacteriia	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158535_k127_2090845_28	309801.trd_A0712	6.173e-35	145.0	COG2971@1|root,COG2971@2|Bacteria,2GA2T@200795|Chloroflexi,27YVG@189775|Thermomicrobia	189775|Thermomicrobia	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158535_k127_2090845_15	1128421.JAGA01000001_gene2307	2.001e-65	244.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158535_k127_2090845_29	1382315.JPOI01000001_gene2860	9.945e-35	144.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4HGXQ@91061|Bacilli,1WFKW@129337|Geobacillus	91061|Bacilli	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	celCD	-	2.7.1.196,2.7.1.205,3.5.1.105	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	YdjC
SRR25158535_k127_2090845_42	864702.OsccyDRAFT_0211	1.858e-16	92.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158535_k127_2090845_41	1183438.GKIL_2793	8.265e-22	111.0	COG1649@1|root,COG1649@2|Bacteria,1G2UW@1117|Cyanobacteria	1117|Cyanobacteria	NU	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SRR25158535_k127_2090845_17	357808.RoseRS_2367	2.562e-61	225.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,375EF@32061|Chloroflexia	32061|Chloroflexia	H	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158535_k127_2090845_19	1156844.KB891806_gene1772	1.643e-55	202.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2090845_25	644966.Tmar_1586	5.645e-41	173.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WD8J@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_2090845_49	1476583.DEIPH_ctg084orf0013	2.632e-05	53.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	Acetyltransf_3
SRR25158535_k127_2090845_38	525904.Tter_0120	1.301e-23	111.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_2090845_27	357808.RoseRS_1757	3.856e-36	141.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,377DW@32061|Chloroflexia	32061|Chloroflexia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158535_k127_2090845_26	479434.Sthe_2734	8.951e-37	146.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_2090845_37	1382306.JNIM01000001_gene1900	6.862e-24	119.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158535_k127_2090845_12	479434.Sthe_2500	5.302e-77	265.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158535_k127_2090845_5	485913.Krac_5061	1.909e-131	426.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2090845_35	1382306.JNIM01000001_gene3579	1.317e-26	123.0	COG3467@1|root,COG3467@2|Bacteria,2G70M@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_2090845_21	1206741.BAFX01000009_gene6882	2.23e-54	208.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4G7CW@85025|Nocardiaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158535_k127_2090845_40	1385519.N801_03005	1.668e-22	106.0	2DQ5G@1|root,334U4@2|Bacteria,2GSBP@201174|Actinobacteria,4FJI9@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2090845_18	525904.Tter_1977	2.294e-57	225.0	COG2141@1|root,COG2141@2|Bacteria,2NQXW@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2090845_4	65497.JODV01000012_gene2389	1.205e-145	477.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria,4E1G6@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR25158535_k127_2090845_48	1146883.BLASA_2186	2.056e-06	54.0	COG4634@1|root,COG4634@2|Bacteria,2H0F6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2090845_39	479434.Sthe_0599	3.773e-23	114.0	COG2318@1|root,COG2318@2|Bacteria,2G98Y@200795|Chloroflexi,27YQK@189775|Thermomicrobia	189775|Thermomicrobia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158535_k127_2090845_7	1385519.N801_15195	1.561e-94	339.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158535_k127_2090845_36	479434.Sthe_0599	2.073e-26	121.0	COG2318@1|root,COG2318@2|Bacteria,2G98Y@200795|Chloroflexi,27YQK@189775|Thermomicrobia	189775|Thermomicrobia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158535_k127_2090845_10	1051632.TPY_1321	4e-79	267.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia	186801|Clostridia	F	PFAM amidohydrolase	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158535_k127_2160851_33	1382306.JNIM01000001_gene1164	2.34e-24	111.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2160851_41	326427.Cagg_2302	1.589e-06	61.0	2DE6H@1|root,2ZKPY@2|Bacteria,2G9I8@200795|Chloroflexi,377JX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_25	448385.sce6849	3.121e-37	163.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
SRR25158535_k127_2160851_39	211165.AJLN01000116_gene2992	2.527e-07	65.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_31	1121468.AUBR01000025_gene2978	3.457e-27	130.0	COG1361@1|root,COG1361@2|Bacteria,1VPQQ@1239|Firmicutes,24WHC@186801|Clostridia,42HPA@68295|Thermoanaerobacterales	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_23	477641.MODMU_4720	7.33e-38	166.0	COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	csp	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
SRR25158535_k127_2160851_32	326427.Cagg_2137	4.772e-27	120.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,3768H@32061|Chloroflexia	32061|Chloroflexia	M	SH3, type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
SRR25158535_k127_2160851_14	477974.Daud_0387	2.957e-92	313.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,261YA@186807|Peptococcaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034,ko:K15586	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_2160851_15	760568.Desku_0104	6.396e-91	308.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,260KR@186807|Peptococcaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	nikB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2160851_7	477974.Daud_0391	7.02e-131	436.0	COG0747@1|root,COG0747@2|Bacteria,1VSRH@1239|Firmicutes,24Y1D@186801|Clostridia,263KC@186807|Peptococcaceae	186801|Clostridia	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2160851_27	479435.Kfla_1399	3.85e-34	153.0	COG2385@1|root,COG2385@2|Bacteria,2I2J0@201174|Actinobacteria,4DQBJ@85009|Propionibacteriales	201174|Actinobacteria	D	PFAM Stage II sporulation D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SpoIID,VCBS
SRR25158535_k127_2160851_29	1121468.AUBR01000025_gene2978	1.216e-30	141.0	COG1361@1|root,COG1361@2|Bacteria,1VPQQ@1239|Firmicutes,24WHC@186801|Clostridia,42HPA@68295|Thermoanaerobacterales	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_37	1173021.ALWA01000025_gene2542	3.561e-11	77.0	COG1361@1|root,COG1361@2|Bacteria,1G19J@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158535_k127_2160851_35	1089553.Tph_c14630	5.721e-17	96.0	COG1361@1|root,COG1361@2|Bacteria,1VPQQ@1239|Firmicutes,24WHC@186801|Clostridia,42HPA@68295|Thermoanaerobacterales	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_19	562970.Btus_0750	9.873e-59	233.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,277ZN@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	apr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158535_k127_2160851_30	1321781.HMPREF1985_02178	6.821e-28	124.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes	909932|Negativicutes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158535_k127_2160851_9	926550.CLDAP_08170	5.086e-129	439.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_2160851_36	67373.JOBF01000022_gene6662	4.654e-14	85.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2IBY8@201174|Actinobacteria	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158535_k127_2160851_22	324602.Caur_3603	6.345e-45	172.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,375AQ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158535_k127_2160851_5	656024.FsymDg_0568	1.414e-156	513.0	COG2865@1|root,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4EXAT@85013|Frankiales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR25158535_k127_2160851_26	1382306.JNIM01000001_gene3951	8.131e-37	144.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi	200795|Chloroflexi	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158535_k127_2160851_10	1047013.AQSP01000138_gene1042	1.409e-125	411.0	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	wcbK	-	1.1.1.281,4.2.1.47	ko:K01711,ko:K15856	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888,R03397,R03399	RC00182,RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158535_k127_2160851_40	479432.Sros_5190	5.003e-07	58.0	COG0406@1|root,COG0406@2|Bacteria,2GTM9@201174|Actinobacteria	201174|Actinobacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_42	68170.KL590505_gene9129	2.191e-06	62.0	COG0739@1|root,COG0739@2|Bacteria,2IGKD@201174|Actinobacteria,4EAQ3@85010|Pseudonocardiales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Ricin_B_lectin
SRR25158535_k127_2160851_28	1343158.SACS_1327	1.869e-31	143.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,2JRT3@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158535_k127_2160851_16	1341151.ASZU01000001_gene681	6.321e-84	303.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,27AV0@186824|Thermoactinomycetaceae	91061|Bacilli	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158535_k127_2160851_4	324602.Caur_1601	2.888e-159	514.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,374UB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158535_k127_2160851_34	426716.JOAJ01000005_gene2883	3.192e-24	119.0	COG2074@1|root,COG2074@2|Bacteria,2GMUY@201174|Actinobacteria,4G0K4@85025|Nocardiaceae	201174|Actinobacteria	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,SKI
SRR25158535_k127_2160851_2	1089553.Tph_c08460	5.476e-198	640.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,42F8R@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRR25158535_k127_2160851_0	204669.Acid345_1977	0.0	1088.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,3Y4JI@57723|Acidobacteria,2JJB0@204432|Acidobacteriia	204432|Acidobacteriia	T	PNKP adenylyltransferase domain, ligase domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
SRR25158535_k127_2160851_3	483219.LILAB_12420	1.062e-184	587.0	COG2227@1|root,COG2227@2|Bacteria,1R6E0@1224|Proteobacteria,42ZTU@68525|delta/epsilon subdivisions,2WVFC@28221|Deltaproteobacteria,2YZN2@29|Myxococcales	28221|Deltaproteobacteria	H	RNA repair, ligase-Pnkp-associating, region of Hen1	ubiE2	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_23
SRR25158535_k127_2160851_43	479434.Sthe_3484	1.748e-05	56.0	COG0630@1|root,COG0630@2|Bacteria,2G943@200795|Chloroflexi,27YBM@189775|Thermomicrobia	189775|Thermomicrobia	NU	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2160851_21	1382306.JNIM01000001_gene1157	7.918e-57	208.0	COG1708@1|root,COG2445@1|root,COG1708@2|Bacteria,COG2445@2|Bacteria,2G9SK@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158535_k127_2160851_18	264732.Moth_2049	5.304e-69	250.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,42EVD@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158535_k127_2160851_44	1382306.JNIM01000001_gene1109	0.0001518	54.0	2F64E@1|root,33YNP@2|Bacteria	2|Bacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N
SRR25158535_k127_2160851_38	397278.JOJN01000003_gene2047	6.282e-10	72.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158535_k127_2160851_12	479434.Sthe_1292	2.45e-109	385.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158535_k127_2160851_8	373903.Hore_22170	1.716e-130	440.0	COG0015@1|root,COG0015@2|Bacteria,1V12Z@1239|Firmicutes,249QU@186801|Clostridia,3WA99@53433|Halanaerobiales	186801|Clostridia	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
SRR25158535_k127_2160851_24	479434.Sthe_1820	1.847e-37	161.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,27YJ0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158535_k127_2160851_13	1123267.JONN01000001_gene1990	1.745e-94	344.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2K0GD@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158535_k127_2160851_1	477974.Daud_1635	1.021e-199	638.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,26041@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158535_k127_2160851_20	1379698.RBG1_1C00001G1510	4.763e-58	230.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_2160851_6	309799.DICTH_1914	1.702e-149	488.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_2160851_11	1382356.JQMP01000003_gene1431	1.459e-115	382.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158535_k127_2160851_17	1120948.KB903217_gene1191	1.258e-82	283.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4DZBP@85010|Pseudonocardiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158535_k127_2183479_18	1307761.L21SP2_1484	7.695e-49	198.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158535_k127_2183479_11	1353529.M899_1638	4.045e-85	290.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,42NZC@68525|delta/epsilon subdivisions,2MSNV@213481|Bdellovibrionales,2WN3Y@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
SRR25158535_k127_2183479_20	1307761.L21SP2_1482	3.286e-43	171.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158535_k127_2183479_13	485913.Krac_10511	1.31e-66	236.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158535_k127_2183479_29	483219.LILAB_16745	1.724e-07	62.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_2183479_9	747365.Thena_0155	2.08e-88	308.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158535_k127_2183479_15	479434.Sthe_1727	1.507e-58	223.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158535_k127_2183479_31	1121861.KB899941_gene3842	0.0009261	51.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,2UEVM@28211|Alphaproteobacteria,2JTKM@204441|Rhodospirillales	204441|Rhodospirillales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2183479_23	1123508.JH636444_gene5257	1.032e-30	130.0	COG3861@1|root,COG3861@2|Bacteria,2J0X2@203682|Planctomycetes	203682|Planctomycetes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2183479_14	1380393.JHVP01000001_gene2285	1.43e-65	254.0	COG1228@1|root,COG1228@2|Bacteria,2IE2S@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2183479_6	562970.Btus_2636	5.271e-113	388.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,277ZT@186823|Alicyclobacillaceae	91061|Bacilli	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158535_k127_2183479_0	1382356.JQMP01000004_gene603	1.095e-243	799.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,27XXG@189775|Thermomicrobia	189775|Thermomicrobia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158535_k127_2183479_1	471852.Tcur_4898	7.426e-204	649.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4EHY6@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR25158535_k127_2183479_24	309801.trd_0871	3.141e-28	130.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,27YDZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_2183479_17	42256.RradSPS_1169	1.22e-56	214.0	COG0122@1|root,COG0122@2|Bacteria,2HGA7@201174|Actinobacteria,4CQF8@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158535_k127_2183479_19	745776.DGo_CA1289	9.647e-45	166.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2183479_22	1121335.Clst_0026	1.885e-32	145.0	COG5401@1|root,COG5401@2|Bacteria,1UIUP@1239|Firmicutes,25ESH@186801|Clostridia,3WJZJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,zf-HC2
SRR25158535_k127_2183479_8	1459636.NTE_01234	5.454e-91	317.0	COG1013@1|root,arCOG01599@2157|Archaea,41SAB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158535_k127_2183479_3	1459636.NTE_01233	1.55e-142	475.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158535_k127_2183479_4	1382359.JIAL01000001_gene773	5.27e-134	441.0	COG1027@1|root,COG1027@2|Bacteria,3Y3XS@57723|Acidobacteria,2JHYF@204432|Acidobacteriia	204432|Acidobacteriia	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158535_k127_2183479_28	479434.Sthe_1381	4.788e-21	100.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,LysM
SRR25158535_k127_2183479_30	1545915.JROG01000003_gene965	1.744e-05	56.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158535_k127_2183479_27	1121422.AUMW01000018_gene1901	2.302e-21	110.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,262PU@186807|Peptococcaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158535_k127_2183479_21	314345.SPV1_07621	1.826e-32	131.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria	1224|Proteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K09565	ko01503,ko04020,ko04022,ko04217,ko05012,ko05016,ko05145,map01503,map04020,map04022,map04217,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158535_k127_2183479_10	477974.Daud_0905	6.036e-86	301.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,26071@186807|Peptococcaceae	186801|Clostridia	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158535_k127_2183479_2	479434.Sthe_1221	1.761e-192	628.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,27XZT@189775|Thermomicrobia	189775|Thermomicrobia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158535_k127_2183479_25	479434.Sthe_3313	2.68e-27	130.0	2A4CF@1|root,30SY3@2|Bacteria,2G9F0@200795|Chloroflexi,27YGU@189775|Thermomicrobia	189775|Thermomicrobia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158535_k127_2183479_5	868595.Desca_2238	4.361e-131	428.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158535_k127_2183479_26	868595.Desca_2237	8.718e-24	115.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,261QI@186807|Peptococcaceae	186801|Clostridia	C	FeS cluster assembly scaffold protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158535_k127_2183479_12	525904.Tter_1033	6.91e-79	289.0	COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158535_k127_2183479_16	1382306.JNIM01000001_gene689	1.443e-57	217.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158535_k127_2183479_7	1121335.Clst_1351	8.095e-93	313.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158535_k127_2222657_5	309807.SRU_1014	9.963e-07	51.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1FIUS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158535_k127_2222657_1	720554.Clocl_3978	4.838e-58	222.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158535_k127_2222657_2	1089548.KI783301_gene2219	7.199e-28	132.0	COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli	91061|Bacilli	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2222657_4	163908.KB235896_gene277	2.197e-13	78.0	COG2020@1|root,COG2020@2|Bacteria,1G6EA@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158535_k127_2222657_0	656024.FsymDg_1327	7.708e-111	366.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria,4ERZN@85013|Frankiales	201174|Actinobacteria	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158535_k127_2222657_3	56780.SYN_00983	9.281e-20	95.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MQ8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158535_k127_2247632_13	59374.Fisuc_0773	7.089e-07	57.0	COG0016@1|root,COG0016@2|Bacteria	2|Bacteria	J	phenylalanine-tRNA ligase activity	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158535_k127_2247632_11	383372.Rcas_1436	4.857e-32	128.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi,375NZ@32061|Chloroflexia	32061|Chloroflexia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158535_k127_2247632_12	1171373.PACID_10180	1.869e-12	69.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4DSHV@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158535_k127_2247632_9	768706.Desor_0144	5.417e-50	186.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,260V8@186807|Peptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158535_k127_2247632_8	1297742.A176_03428	4.032e-50	194.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria,2YVI4@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_2247632_1	665571.STHERM_c16030	6.258e-202	656.0	COG0441@1|root,COG0441@2|Bacteria,2J5ID@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158535_k127_2247632_10	1340493.JNIF01000003_gene4465	2.715e-49	197.0	COG1305@1|root,COG1305@2|Bacteria,3Y3J9@57723|Acidobacteria	57723|Acidobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158535_k127_2247632_7	326427.Cagg_2255	3.146e-50	191.0	COG2307@1|root,COG2307@2|Bacteria,2GAAJ@200795|Chloroflexi,374SB@32061|Chloroflexia	32061|Chloroflexia	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158535_k127_2247632_2	326427.Cagg_2256	7.496e-188	612.0	COG2308@1|root,COG2308@2|Bacteria,2GACA@200795|Chloroflexi,37575@32061|Chloroflexia	32061|Chloroflexia	S	A circularly permuted ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158535_k127_2247632_6	656024.FsymDg_3703	8.769e-55	205.0	COG1305@1|root,COG1305@2|Bacteria,2IIM2@201174|Actinobacteria	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158535_k127_2247632_3	649638.Trad_1996	5.714e-97	325.0	COG1305@1|root,COG1305@2|Bacteria,1WMFC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158535_k127_2247632_5	1121468.AUBR01000016_gene2299	3.155e-58	221.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,24GK7@186801|Clostridia,42I8X@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158535_k127_2247632_0	485913.Krac_7555	3.31e-300	944.0	COG0493@1|root,COG0493@2|Bacteria,2G82F@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Fer2_4,Fer4,Fer4_20,Pyr_redox_2
SRR25158535_k127_2247632_4	1168034.FH5T_01545	5.594e-59	221.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,2FN7A@200643|Bacteroidia	976|Bacteroidetes	C	COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158535_k127_2247632_14	1382306.JNIM01000001_gene994	6.772e-06	52.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	echF	-	1.6.5.3	ko:K00338,ko:K14091	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_10,Fer4_7
SRR25158535_k127_2298952_4	309801.trd_0641	1.452e-101	338.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,27XFG@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158535_k127_2298952_1	479434.Sthe_1670	1.559e-165	548.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,27XEM@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158535_k127_2298952_0	309801.trd_1255	5.424e-168	546.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2298952_3	1382356.JQMP01000004_gene273	6.275e-127	413.0	COG0601@1|root,COG0601@2|Bacteria,2G5Z7@200795|Chloroflexi,27XQJ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2298952_5	489825.LYNGBM3L_26950	9.477e-101	349.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria,1H91N@1150|Oscillatoriales	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_2298952_6	1437824.BN940_13236	4.946e-50	185.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2W3S9@28216|Betaproteobacteria,3T93X@506|Alcaligenaceae	28216|Betaproteobacteria	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158535_k127_2298952_2	1121428.DESHY_110201___1	4.442e-154	519.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158535_k127_2302550_15	1382306.JNIM01000001_gene1765	1.614e-57	224.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158535_k127_2302550_18	525904.Tter_1442	8.656e-46	186.0	COG4587@1|root,COG4587@2|Bacteria,2NQY6@2323|unclassified Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158535_k127_2302550_4	1128421.JAGA01000002_gene1693	9.57e-119	391.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2302550_14	525904.Tter_1705	2.513e-58	216.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107	ko:K04771,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158535_k127_2302550_11	717605.Theco_2065	5.933e-80	280.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158535_k127_2302550_20	760568.Desku_2555	1.638e-29	131.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,261ZV@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158535_k127_2302550_13	1123393.KB891317_gene2296	9.118e-71	248.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1KRG8@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Putative undecaprenyl diphosphate synthase	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158535_k127_2302550_17	926569.ANT_03510	9.231e-54	205.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158535_k127_2302550_9	1201292.DR75_1145	1.505e-85	290.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,4AZ74@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
SRR25158535_k127_2302550_19	479434.Sthe_1735	7.463e-37	153.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi,27Y81@189775|Thermomicrobia	189775|Thermomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158535_k127_2302550_6	1382306.JNIM01000001_gene1332	1.988e-93	325.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158535_k127_2302550_28	1120998.AUFC01000036_gene1283	1.516e-05	49.0	2EHTG@1|root,33BJ4@2|Bacteria	2|Bacteria	S	Flp Fap pilin component	-	-	-	-	-	-	-	-	-	-	-	-	Flp_Fap
SRR25158535_k127_2302550_27	867845.KI911784_gene1555	7.298e-06	50.0	COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia	32061|Chloroflexia	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158535_k127_2302550_2	324602.Caur_1621	3.429e-150	507.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,2G5P4@200795|Chloroflexi,374UA@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
SRR25158535_k127_2302550_1	525904.Tter_0805	8.117e-171	557.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158535_k127_2302550_25	1502851.FG93_02216	6.978e-09	66.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,3JR3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_2302550_10	368408.Tpen_0832	2.727e-83	307.0	COG0330@1|root,arCOG01915@2157|Archaea,2XPQN@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158535_k127_2302550_8	479434.Sthe_1855	6.06e-86	305.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158535_k127_2302550_5	926560.KE387027_gene366	4.198e-108	373.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_2302550_0	215803.DB30_4063	1.505e-222	701.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158535_k127_2302550_7	1223523.H340_31373	4.327e-90	314.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria	201174|Actinobacteria	S	Neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158535_k127_2302550_26	1123226.KB899279_gene2553	8.78e-07	63.0	COG4632@1|root,COG4632@2|Bacteria,1V0JD@1239|Firmicutes,4HFC0@91061|Bacilli,27642@186822|Paenibacillaceae	91061|Bacilli	G	copper amine oxidase	gapag	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA
SRR25158535_k127_2302550_23	525904.Tter_2165	2.912e-23	114.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158535_k127_2302550_12	42256.RradSPS_1447	9.689e-74	277.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CPPD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158535_k127_2302550_16	751945.Theos_0606	4.368e-55	211.0	COG0077@1|root,COG0077@2|Bacteria,1WIGR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158535_k127_2302550_24	1128421.JAGA01000003_gene3433	3.518e-21	108.0	COG4401@1|root,COG4401@2|Bacteria	2|Bacteria	E	Chorismate mutase type I	aroH	GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704	2.7.4.25,5.4.99.5	ko:K00945,ko:K06208	ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230	M00024,M00025,M00052	R00158,R00512,R01665,R01715	RC00002,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158535_k127_2302550_3	706587.Desti_1323	2.524e-120	404.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MRCR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM DAHP synthetase I	aroG-2	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158535_k127_2302550_21	196162.Noca_2500	2.107e-23	115.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4DNB5@85009|Propionibacteriales	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158535_k127_2302550_22	1122223.KB890688_gene1782	2.718e-23	113.0	COG0169@1|root,COG0169@2|Bacteria,1WIM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158535_k127_2314445_8	1206731.BAGB01000063_gene7396	9.754e-22	100.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158535_k127_2314445_1	1118054.CAGW01000075_gene3264	6.424e-81	284.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,26QR3@186822|Paenibacillaceae	91061|Bacilli	P	Nitrate ABC transporter ATP-binding protein	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158535_k127_2314445_3	1122915.AUGY01000118_gene6523	1.702e-52	199.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_2314445_4	224911.27354324	1.437e-49	194.0	COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,2U2YE@28211|Alphaproteobacteria,3JTTU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.17.2.1	ko:K18029	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_2314445_0	1298867.AUES01000014_gene4275	8.925e-181	595.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JRND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_2314445_9	68570.DC74_1065	2.585e-14	79.0	2ATY8@1|root,31JHU@2|Bacteria,2IEIB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur
SRR25158535_k127_2314445_5	292459.STH607	3.02e-44	176.0	COG0577@1|root,COG0577@2|Bacteria,1TUYK@1239|Firmicutes,24DGM@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2314445_2	1123322.KB904698_gene4703	2.865e-59	229.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2314445_6	665956.HMPREF1032_01871	2.333e-34	140.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158535_k127_2314445_10	316067.Geob_1639	9.833e-10	70.0	COG1361@1|root,COG1404@1|root,COG3055@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,1RC5K@1224|Proteobacteria,42U2I@68525|delta/epsilon subdivisions,2WQAT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158535_k127_2314445_7	929712.KI912613_gene1901	6.636e-25	108.0	COG2452@1|root,COG3585@1|root,COG2452@2|Bacteria,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4CQRP@84995|Rubrobacteria	84995|Rubrobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,TOBE
SRR25158535_k127_2391435_10	357808.RoseRS_3583	9.565e-33	142.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2391435_7	397948.Cmaq_0619	2.237e-60	216.0	COG0463@1|root,arCOG00894@2157|Archaea,2XQ9U@28889|Crenarchaeota	28889|Crenarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158535_k127_2391435_11	709986.Deima_0738	2.297e-21	109.0	COG0454@1|root,COG0456@2|Bacteria,1WMM3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_2391435_1	1267533.KB906735_gene4492	4.86e-116	385.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria,2JKCR@204432|Acidobacteriia	204432|Acidobacteriia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158535_k127_2391435_4	479433.Caci_8500	5.564e-89	305.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158535_k127_2391435_12	643648.Slip_0214	1.085e-08	64.0	COG1848@1|root,COG1848@2|Bacteria,1U5UN@1239|Firmicutes,25P95@186801|Clostridia,42KUD@68298|Syntrophomonadaceae	186801|Clostridia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_2391435_6	323097.Nham_3040	2.301e-67	252.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2U0PZ@28211|Alphaproteobacteria,3JUJG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158535_k127_2391435_0	525904.Tter_2810	1.094e-125	413.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158535_k127_2391435_3	1267535.KB906767_gene1741	3e-95	322.0	COG0673@1|root,COG0673@2|Bacteria,3Y486@57723|Acidobacteria,2JHJI@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158535_k127_2391435_8	247490.KSU1_D0930	2.412e-52	214.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	2|Bacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8,Radical_SAM,SPASM
SRR25158535_k127_2391435_2	1408224.SAMCCGM7_c5591	2.136e-102	370.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_2391435_13	1172180.KB911786_gene88	7.607e-07	64.0	COG3250@1|root,COG3291@1|root,COG3507@1|root,COG5492@1|root,COG3250@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG5492@2|Bacteria,2GK37@201174|Actinobacteria	201174|Actinobacteria	N	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Big_4,Glyco_hydro_43,Laminin_G_3
SRR25158535_k127_2391435_5	382464.ABSI01000013_gene1571	1.448e-74	289.0	COG1572@1|root,COG3210@1|root,COG3386@1|root,COG4257@1|root,COG5373@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4257@2|Bacteria,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	ko:K13277,ko:K15125,ko:K15539	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110	-	-	-	DUF5011
SRR25158535_k127_2391435_9	886293.Sinac_4934	2.149e-49	205.0	COG3420@1|root,COG3420@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2391435_14	118168.MC7420_2377	0.0001396	57.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
SRR25158535_k127_242489_12	479434.Sthe_1248	1.766e-08	57.0	COG1826@1|root,COG1826@2|Bacteria,2GAXB@200795|Chloroflexi,27YQN@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_242489_7	1121033.AUCF01000032_gene2603	3.581e-32	134.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,2JS5Z@204441|Rhodospirillales	204441|Rhodospirillales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
SRR25158535_k127_242489_6	309801.trd_0359	2.874e-41	166.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia	189775|Thermomicrobia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158535_k127_242489_1	457570.Nther_2188	1.328e-91	326.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_242489_10	1082933.MEA186_09690	4.737e-14	86.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria,43N9X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158535_k127_242489_11	525904.Tter_1024	1.162e-08	67.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	tadG1	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_242489_3	1382356.JQMP01000003_gene2441	1.803e-70	260.0	COG0747@1|root,COG0747@2|Bacteria,2GA2U@200795|Chloroflexi,27YVV@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_242489_2	649638.Trad_0942	2.395e-76	267.0	COG0601@1|root,COG0601@2|Bacteria,1WIGY@1297|Deinococcus-Thermus	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_242489_5	1382356.JQMP01000003_gene2439	8.162e-61	233.0	COG1173@1|root,COG1173@2|Bacteria,2GBDG@200795|Chloroflexi,27YY2@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_242489_8	227377.CBU_1788	3.56e-26	110.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
SRR25158535_k127_242489_13	1122621.ATZA01000008_gene862	1.608e-05	50.0	COG3646@1|root,COG3646@2|Bacteria,4NPHX@976|Bacteroidetes,1ISKY@117747|Sphingobacteriia	976|Bacteroidetes	S	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
SRR25158535_k127_242489_0	292459.STH2403	5.193e-98	348.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158535_k127_242489_4	525904.Tter_1691	2.088e-62	222.0	COG1811@1|root,COG1811@2|Bacteria,2NPEK@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF554)	ydfK	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158535_k127_242489_9	1054213.HMPREF9946_02703	8.884e-25	109.0	COG1051@1|root,COG1051@2|Bacteria,1RH0I@1224|Proteobacteria,2UB84@28211|Alphaproteobacteria,2JWEM@204441|Rhodospirillales	204441|Rhodospirillales	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
SRR25158535_k127_2434865_2	266117.Rxyl_2569	8.037e-63	221.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4931
SRR25158535_k127_2434865_6	658655.HMPREF0988_02730	8.029e-12	76.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,27PRP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158535_k127_2434865_8	1184607.AUCHE_05_01460	0.0007889	49.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria,4F81J@85018|Dermatophilaceae	201174|Actinobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
SRR25158535_k127_2434865_7	1219045.BV98_002168	3.22e-10	71.0	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria,2U3RM@28211|Alphaproteobacteria,2K4NF@204457|Sphingomonadales	204457|Sphingomonadales	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_2434865_5	555088.DealDRAFT_1127	4.258e-28	123.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158535_k127_2434865_3	745776.DGo_CA2068	2.716e-60	213.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158535_k127_2434865_0	1521187.JPIM01000042_gene1868	1.553e-102	346.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,376MF@32061|Chloroflexia	32061|Chloroflexia	F	PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158535_k127_2434865_1	316274.Haur_4100	8.574e-95	340.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi,3755Y@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_2434865_4	575540.Isop_3353	2.651e-36	150.0	COG0505@1|root,COG0505@2|Bacteria,2IWSY@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158535_k127_2527328_3	926550.CLDAP_07310	7.46e-67	244.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158535_k127_2527328_7	292459.STH1866	5.551e-41	163.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158535_k127_2527328_5	1896.JOAU01000002_gene4093	1.504e-53	215.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria	201174|Actinobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158535_k127_2527328_1	479434.Sthe_1878	1.408e-119	419.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia	189775|Thermomicrobia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158535_k127_2527328_4	1382356.JQMP01000004_gene436	1.599e-64	245.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,27XSP@189775|Thermomicrobia	189775|Thermomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158535_k127_2527328_0	525904.Tter_1249	7.688e-160	514.0	COG0133@1|root,COG0133@2|Bacteria,2NNWF@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2527328_6	1385521.N803_08895	2.3e-42	168.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4FFW9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158535_k127_2527328_2	1121430.JMLG01000010_gene185	3.628e-95	331.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158535_k127_2527328_10	309801.trd_0791	0.0005741	52.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi,27YHK@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
SRR25158535_k127_2527328_9	105420.BBPO01000051_gene1886	1.651e-13	82.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,2NIK7@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158535_k127_2527328_8	1356852.N008_00270	5.538e-38	147.0	COG0189@1|root,COG0189@2|Bacteria,4NJI8@976|Bacteroidetes,47JGF@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158535_k127_2549233_8	401526.TcarDRAFT_0671	9.912e-24	107.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,4H4QB@909932|Negativicutes	909932|Negativicutes	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_2549233_1	568816.Acin_0007	8.916e-210	690.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H2D7@909932|Negativicutes	909932|Negativicutes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158535_k127_2549233_5	309801.trd_1054	2.66e-65	238.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158535_k127_2549233_3	292459.STH3333	1.72e-82	284.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158535_k127_2549233_10	926550.CLDAP_08150	0.0006268	50.0	COG2891@1|root,COG2891@2|Bacteria	2|Bacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158535_k127_2549233_2	926569.ANT_09720	7.767e-101	354.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158535_k127_2549233_4	1009370.ALO_07958	1.866e-77	286.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4H21I@909932|Negativicutes	909932|Negativicutes	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_2549233_0	479434.Sthe_1438	2.18e-308	969.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158535_k127_2549233_9	861299.J421_1466	1.048e-05	57.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2549233_7	593907.Celgi_1213	1.761e-30	127.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4F2PZ@85016|Cellulomonadaceae	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158535_k127_2549233_6	446462.Amir_1203	3.438e-64	249.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158535_k127_255451_29	479434.Sthe_0796	1.988e-22	101.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158535_k127_255451_0	479434.Sthe_1621	0.0	1339.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
SRR25158535_k127_255451_23	479434.Sthe_1686	9.989e-42	167.0	COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria,2G7IY@200795|Chloroflexi	200795|Chloroflexi	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158535_k127_255451_20	869210.Marky_1584	3.656e-45	187.0	COG0477@1|root,COG2814@2|Bacteria,1WJC5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_255451_1	309801.trd_A0202	1.298e-224	724.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,27XZR@189775|Thermomicrobia	189775|Thermomicrobia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,LUD_dom
SRR25158535_k127_255451_6	189425.PGRAT_28600	5.405e-109	381.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,26RUX@186822|Paenibacillaceae	91061|Bacilli	P	Arsenical pump membrane protein	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	CitMHS
SRR25158535_k127_255451_5	1382306.JNIM01000001_gene1613	9.903e-119	414.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SRR25158535_k127_255451_21	266117.Rxyl_2832	7.684e-44	184.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CRXQ@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_255451_3	1382306.JNIM01000001_gene1617	2.769e-160	533.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_255451_19	42256.RradSPS_1310	2.64e-53	199.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,4CT12@84995|Rubrobacteria	84995|Rubrobacteria	K	regulator IclR	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158535_k127_255451_2	1382356.JQMP01000003_gene2403	1.333e-171	561.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi,27Y2A@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158535_k127_255451_25	1123075.AUDP01000022_gene3603	5.032e-35	138.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,3WKWD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158535_k127_255451_32	425104.Ssed_3506	5.891e-09	68.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,2Q9SH@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158535_k127_255451_36	926569.ANT_06730	2.175e-06	60.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_255451_11	926569.ANT_02350	4.721e-93	319.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_255451_24	865861.AZSU01000001_gene386	4.018e-35	153.0	COG0842@1|root,COG0842@2|Bacteria,1VI3K@1239|Firmicutes,24AR2@186801|Clostridia,36F7U@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158535_k127_255451_28	926569.ANT_02330	1.178e-30	139.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_255451_27	1540221.JQNI01000004_gene136	4.43e-32	139.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_255451_30	1276920.ADIAG_00594	2.221e-20	94.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,1W9SA@1268|Micrococcaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158535_k127_255451_13	298654.FraEuI1c_4882	3.905e-75	268.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EREI@85013|Frankiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158535_k127_255451_22	404589.Anae109_2280	6.531e-43	177.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158535_k127_255451_4	264732.Moth_0265	1.924e-150	496.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,42FP5@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158535_k127_255451_35	1128421.JAGA01000002_gene1001	5.766e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158535_k127_255451_31	255470.cbdbA1641	1.685e-10	66.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,34DHN@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158535_k127_255451_7	479434.Sthe_1249	1.808e-101	350.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_255451_34	1071073.KI530537_gene2076	4.277e-08	65.0	COG1372@1|root,COG1372@2|Bacteria,1VPYF@1239|Firmicutes,4HSTN@91061|Bacilli,1ZEPN@1386|Bacillus	91061|Bacilli	L	LAGLIDADG-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3
SRR25158535_k127_255451_14	543632.JOJL01000035_gene5070	1.03e-64	232.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158535_k127_255451_12	768671.ThimaDRAFT_4664	6.068e-79	272.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158535_k127_255451_18	926569.ANT_31600	2.628e-55	204.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_255451_8	479434.Sthe_1099	7.139e-101	342.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_255451_10	1382306.JNIM01000001_gene1297	8.148e-95	320.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158535_k127_255451_16	986075.CathTA2_1020	3.958e-60	232.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli	91061|Bacilli	V	Mate efflux family protein	norN	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158535_k127_255451_26	452662.SJA_C1-10270	5.181e-33	133.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,2K4FQ@204457|Sphingomonadales	204457|Sphingomonadales	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158535_k127_255451_9	1123024.AUII01000026_gene2555	7.754e-96	327.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4E1JP@85010|Pseudonocardiales	201174|Actinobacteria	S	FIST N domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158535_k127_255451_37	411477.PARMER_01457	0.0001577	50.0	2DFVK@1|root,2ZTBH@2|Bacteria,4PIGB@976|Bacteroidetes,2G1SY@200643|Bacteroidia,2318W@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_255451_15	448385.sce8846	2.111e-60	212.0	COG0640@1|root,COG0640@2|Bacteria,1RH4V@1224|Proteobacteria,43AH1@68525|delta/epsilon subdivisions,2X5X1@28221|Deltaproteobacteria,2Z038@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158535_k127_255451_17	1144275.COCOR_03456	3.818e-56	198.0	COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria	1224|Proteobacteria	K	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_2558498_6	710687.KI912270_gene1659	3.818e-52	194.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,236CB@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2558498_5	324602.Caur_3465	3.969e-64	225.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158535_k127_2558498_3	867845.KI911784_gene215	1.387e-81	289.0	COG2905@1|root,COG2905@2|Bacteria,2G600@200795|Chloroflexi	200795|Chloroflexi	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR25158535_k127_2558498_8	604331.AUHY01000014_gene2540	4.418e-36	158.0	COG0847@1|root,COG5000@1|root,COG0847@2|Bacteria,COG5000@2|Bacteria,1WJES@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	PAS_8,RNase_T
SRR25158535_k127_2558498_16	671143.DAMO_0162	2.653e-05	56.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158535_k127_2558498_11	1240349.ANGC01000014_gene564	7.104e-22	109.0	COG0745@1|root,COG0745@2|Bacteria,2GNQH@201174|Actinobacteria,4FV18@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2558498_2	684949.ATTJ01000002_gene429	2.212e-107	361.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,1WJRN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_3
SRR25158535_k127_2558498_0	926550.CLDAP_07150	9.846e-229	727.0	COG4263@1|root,COG4263@2|Bacteria,2G8B2@200795|Chloroflexi	200795|Chloroflexi	C	nitrous-oxide reductase activity	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158535_k127_2558498_12	1382356.JQMP01000003_gene2449	1.258e-16	84.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2558498_10	684949.ATTJ01000003_gene3215	1.306e-22	116.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
SRR25158535_k127_2558498_7	756499.Desde_0188	2.207e-41	178.0	COG3420@1|root,COG3420@2|Bacteria,1U542@1239|Firmicutes,24Z13@186801|Clostridia,264G0@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
SRR25158535_k127_2558498_9	756883.Halar_2421	4.643e-25	115.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2558498_15	1453503.AU05_24065	1.001e-05	53.0	COG0454@1|root,COG0456@2|Bacteria,1NHGD@1224|Proteobacteria,1SS8U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_2558498_1	106370.Francci3_0083	7.186e-209	657.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4ESB0@85013|Frankiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158535_k127_2558498_4	543632.JOJL01000002_gene8164	2.539e-78	270.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DB09@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_2558498_14	1192868.CAIU01000013_gene1616	5.486e-09	64.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,43QUB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158535_k127_2558498_13	1324957.K933_11981	7.16e-12	72.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23TI5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_2560196_8	643648.Slip_0438	3.71e-23	104.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,42KQ9@68298|Syntrophomonadaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158535_k127_2560196_7	665942.HMPREF1022_01582	8.503e-50	187.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2M7W9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158535_k127_2560196_3	767817.Desgi_0452	7.639e-97	330.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,26184@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158535_k127_2560196_5	1120950.KB892709_gene4045	1.346e-62	222.0	COG2808@1|root,COG2808@2|Bacteria,2I9QJ@201174|Actinobacteria	201174|Actinobacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158535_k127_2560196_2	429009.Adeg_1833	1.892e-98	332.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,42F2M@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158535_k127_2560196_1	479434.Sthe_1942	3.156e-143	466.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,27XVS@189775|Thermomicrobia	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158535_k127_2560196_4	644966.Tmar_1991	4.807e-94	322.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WCD3@538999|Clostridiales incertae sedis	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158535_k127_2560196_6	558173.CDOO_07665	3.442e-53	194.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,22M8W@1653|Corynebacteriaceae	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158535_k127_2560196_0	1121403.AUCV01000025_gene2223	2.889e-148	506.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158535_k127_2560196_9	365528.KB891218_gene1526	3.399e-14	82.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4ESTJ@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158535_k127_2566938_23	928724.SacglDRAFT_04257	5.637e-44	164.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DYUX@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158535_k127_2566938_0	1382356.JQMP01000003_gene2420	0.0	1104.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158535_k127_2566938_32	880073.Calab_1555	8.405e-13	80.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
SRR25158535_k127_2566938_26	1382356.JQMP01000004_gene630	7.883e-40	152.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,27YAD@189775|Thermomicrobia	189775|Thermomicrobia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158535_k127_2566938_36	1034769.KB910518_gene1295	1.489e-08	67.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1UYX5@1239|Firmicutes,4HF70@91061|Bacilli,26QGI@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K20342,ko:K20391	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
SRR25158535_k127_2566938_2	309801.trd_0567	4.056e-170	552.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,27Y1W@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-hairpin-helix domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158535_k127_2566938_33	1158318.ATXC01000002_gene1668	2.16e-11	74.0	COG1254@1|root,COG1254@2|Bacteria,2G49Q@200783|Aquificae	200783|Aquificae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158535_k127_2566938_5	266117.Rxyl_1110	1.338e-147	483.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158535_k127_2566938_3	935948.KE386494_gene641	2.268e-150	492.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,42EZN@68295|Thermoanaerobacterales	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
SRR25158535_k127_2566938_34	765913.ThidrDRAFT_1505	3.266e-11	66.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ1Y@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158535_k127_2566938_19	525904.Tter_0922	1.478e-58	217.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158535_k127_2566938_12	316274.Haur_2249	3.622e-101	362.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2566938_25	552811.Dehly_0334	1.209e-40	162.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi,34CZI@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158535_k127_2566938_7	1382306.JNIM01000001_gene1299	7.459e-118	393.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158535_k127_2566938_10	401526.TcarDRAFT_0978	1.474e-108	360.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H22D@909932|Negativicutes	909932|Negativicutes	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158535_k127_2566938_31	1192034.CAP_7284	4.141e-13	81.0	293AQ@1|root,2ZQTE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2566938_18	298653.Franean1_4183	8.652e-61	231.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4ETN1@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158535_k127_2566938_28	1284775.HMPREF1640_12425	2.132e-33	137.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR25158535_k127_2566938_21	1379698.RBG1_1C00001G1221	3.396e-53	201.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158535_k127_2566938_8	1379698.RBG1_1C00001G1220	1.547e-111	377.0	COG0620@1|root,COG0620@2|Bacteria,2NPAE@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Meth_synt_1,Meth_synt_2
SRR25158535_k127_2566938_4	1123024.AUII01000021_gene69	1.709e-148	484.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158535_k127_2566938_1	1297569.MESS2_1130009	1.583e-219	692.0	COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,2TVKJ@28211|Alphaproteobacteria,43JC5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	FAD binding domain	MA20_22130	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
SRR25158535_k127_2566938_6	1122622.ATWJ01000002_gene800	2.791e-133	448.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158535_k127_2566938_11	479434.Sthe_2380	4.813e-108	363.0	COG0513@1|root,COG0513@2|Bacteria,2G5VR@200795|Chloroflexi,27XXB@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158535_k127_2566938_20	523850.TON_1608	4.629e-56	224.0	COG0274@1|root,arCOG04320@2157|Archaea,2XT2D@28890|Euryarchaeota,242NJ@183968|Thermococci	183968|Thermococci	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158535_k127_2566938_16	311424.DhcVS_675	6.487e-65	246.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158535_k127_2566938_27	867903.ThesuDRAFT_02359	1.114e-35	149.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158535_k127_2566938_14	383372.Rcas_3582	5.458e-76	273.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi,375CI@32061|Chloroflexia	32061|Chloroflexia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158535_k127_2566938_24	926692.AZYG01000092_gene1707	8.416e-44	174.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WAS8@53433|Halanaerobiales	186801|Clostridia	H	molybdenum cofactor	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SRR25158535_k127_2566938_22	298655.KI912266_gene1785	7.378e-47	187.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4ESM0@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158535_k127_2566938_9	479434.Sthe_1113	2.477e-110	373.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi,27XRV@189775|Thermomicrobia	189775|Thermomicrobia	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158535_k127_2566938_30	1210908.HSB1_17820	4.546e-15	85.0	arCOG11098@1|root,arCOG11098@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2566938_35	926690.KE386573_gene2831	6.28e-11	68.0	arCOG06302@1|root,arCOG06302@2157|Archaea,2Y0EF@28890|Euryarchaeota,23XJG@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CopD,DUF2214
SRR25158535_k127_2566938_29	1386089.N865_19180	1.121e-28	132.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4FGN5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2566938_13	56780.SYN_00839	3.109e-78	290.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42S6I@68525|delta/epsilon subdivisions,2WNNW@28221|Deltaproteobacteria,2MQGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
SRR25158535_k127_2566938_17	671143.DAMO_1144	2.257e-64	227.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
SRR25158535_k127_2566938_15	1382356.JQMP01000003_gene1639	7.394e-74	254.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
SRR25158535_k127_2567398_5	1040989.AWZU01000011_gene4086	3.828e-49	183.0	COG1011@1|root,COG1011@2|Bacteria,1PU30@1224|Proteobacteria,2U5J4@28211|Alphaproteobacteria,3JYJ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158535_k127_2567398_4	861299.J421_5977	1.578e-87	308.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_2567398_2	926569.ANT_11050	3.654e-142	464.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158535_k127_2567398_3	235909.GK1761	1.972e-139	457.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HCEB@91061|Bacilli,1WFTY@129337|Geobacillus	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2567398_9	452863.Achl_1129	2.1e-05	55.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2567398_0	479434.Sthe_2024	1.933e-183	584.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2567398_7	483219.LILAB_10780	6.889e-30	129.0	COG5002@1|root,COG5002@2|Bacteria,1QUJ9@1224|Proteobacteria,42MEB@68525|delta/epsilon subdivisions,2X85R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS
SRR25158535_k127_2567398_1	1128421.JAGA01000002_gene1751	8.42e-159	509.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158535_k127_2567398_8	1125699.HMPREF9194_01044	6.197e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,2J7CK@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657,ko:K07658,ko:K18941	ko02020,map02020	M00434,M00716,M00717	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2567398_6	1316927.ATKI01000034_gene4683	5.491e-40	157.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YT39@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158535_k127_2608402_34	266117.Rxyl_2934	2.019e-34	138.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158535_k127_2608402_3	1463895.JODA01000018_gene5927	2.428e-130	426.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2608402_7	357808.RoseRS_3775	5.412e-107	362.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2608402_43	861299.J421_3199	8.066e-19	91.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158535_k127_2608402_54	1382356.JQMP01000003_gene1395	7.772e-06	53.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2608402_0	479434.Sthe_2381	1.069e-242	781.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi,27XH3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158535_k127_2608402_13	525904.Tter_1794	1.475e-88	309.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iJN678.pfkA	PFK
SRR25158535_k127_2608402_16	1137269.AZWL01000027_gene1713	2.559e-81	285.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria	201174|Actinobacteria	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158535_k127_2608402_2	1121033.AUCF01000001_gene2566	2.168e-130	423.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158535_k127_2608402_56	999541.bgla_1g17410	0.0001016	55.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,1K26R@119060|Burkholderiaceae	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SRR25158535_k127_2608402_31	525904.Tter_0120	6.481e-41	164.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_2608402_22	448385.sce5671	6.682e-60	213.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_2608402_4	525904.Tter_1654	1.682e-115	396.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158535_k127_2608402_21	1121468.AUBR01000011_gene2472	2.772e-61	233.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,42F2N@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
SRR25158535_k127_2608402_18	1094508.Tsac_0324	4.021e-74	254.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,42GF5@68295|Thermoanaerobacterales	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158535_k127_2608402_40	697281.Mahau_0239	2.592e-24	110.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158535_k127_2608402_38	1247963.JPHU01000009_gene2401	5.66e-28	114.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158535_k127_2608402_48	324602.Caur_2318	3.577e-14	83.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,375U1@32061|Chloroflexia	32061|Chloroflexia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158535_k127_2608402_32	1006000.GKAS_03539	6.071e-38	154.0	2EYVG@1|root,33S2J@2|Bacteria,1NQGV@1224|Proteobacteria,1SJUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158535_k127_2608402_20	383372.Rcas_2962	2.831e-65	230.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,375G8@32061|Chloroflexia	32061|Chloroflexia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158535_k127_2608402_29	1382356.JQMP01000003_gene1447	6.17e-48	195.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158535_k127_2608402_15	518766.Rmar_0068	3.124e-86	300.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2608402_10	1009370.ALO_05910	2.22e-91	326.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2608402_37	316274.Haur_0876	1.449e-30	125.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158535_k127_2608402_50	41875.XP_007512570.1	4.099e-12	75.0	COG2940@1|root,KOG4442@2759|Eukaryota,37JP7@33090|Viridiplantae,34JBG@3041|Chlorophyta	3041|Chlorophyta	U	associated with SET domains	-	-	2.1.1.43	ko:K11423	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	SET,zf-CW
SRR25158535_k127_2608402_1	246194.CHY_0124	4.625e-137	454.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42ERB@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158535_k127_2608402_42	1121377.KB906408_gene1133	6.485e-20	103.0	COG0477@1|root,COG2814@2|Bacteria,1WIWD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2608402_23	1521187.JPIM01000006_gene1707	7.943e-59	218.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_2608402_6	671143.DAMO_2883	1.852e-110	386.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158535_k127_2608402_46	1125971.ASJB01000031_gene1241	1.816e-15	85.0	COG3409@1|root,COG3409@2|Bacteria,2HUBB@201174|Actinobacteria,4E7IY@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2608402_36	926569.ANT_14790	5.225e-31	131.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158535_k127_2608402_8	670487.Ocepr_0258	1.422e-106	364.0	COG1543@1|root,COG1543@2|Bacteria,1WIRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	hydrolase family 57	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158535_k127_2608402_14	404589.Anae109_0594	1.816e-86	298.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,42VPN@68525|delta/epsilon subdivisions,2WRK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2608402_9	426355.Mrad2831_3809	4.573e-94	323.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,1JQQ3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DEAD DEAH box helicase domain protein	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158535_k127_2608402_35	290397.Adeh_2634	1.733e-33	149.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CCF@68525|delta/epsilon subdivisions,2X60X@28221|Deltaproteobacteria,2Z384@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_2608402_45	292415.Tbd_2614	3.646e-16	89.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_2608402_41	264732.Moth_1992	4.529e-20	102.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2608402_55	365044.Pnap_1257	1.751e-05	57.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2608402_44	215803.DB30_5775	8.894e-18	88.0	COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,4352K@68525|delta/epsilon subdivisions,2WZDN@28221|Deltaproteobacteria,2Z1WQ@29|Myxococcales	28221|Deltaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2608402_17	644966.Tmar_0772	5.659e-80	284.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_2608402_12	644966.Tmar_0771	1.294e-88	314.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2608402_5	926560.KE387025_gene3982	1.901e-113	390.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2608402_19	926560.KE387025_gene3981	1.433e-70	252.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2608402_11	926560.KE387025_gene3980	5.226e-90	320.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2608402_28	479434.Sthe_2653	5.407e-49	185.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158535_k127_2608402_33	926560.KE387025_gene3987	3.043e-37	156.0	COG0785@1|root,COG0785@2|Bacteria,1WIZH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR25158535_k127_2608402_39	1408303.JNJJ01000078_gene1188	1.08e-27	119.0	COG4263@1|root,COG4263@2|Bacteria	2|Bacteria	C	nitrous-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2608402_53	1121272.KB903290_gene4753	2.964e-06	58.0	COG3462@1|root,COG3462@2|Bacteria,2HWVS@201174|Actinobacteria,4DKHI@85008|Micromonosporales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158535_k127_2608402_52	1380763.BG53_02850	2.182e-06	57.0	COG4454@1|root,COG4454@2|Bacteria,1V23W@1239|Firmicutes,4HGGT@91061|Bacilli,2717N@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2608402_49	587753.EY04_09475	2.421e-13	81.0	COG4454@1|root,COG4454@2|Bacteria,1RC48@1224|Proteobacteria,1T0G9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Copper-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_2608402_24	1079986.JH164837_gene5939	3.431e-58	205.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158535_k127_2608402_30	378806.STAUR_5411	1.706e-42	172.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2YW9W@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158535_k127_2608402_27	1122611.KB903990_gene7226	1.187e-50	190.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158535_k127_2608402_25	525904.Tter_0756	6.833e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2608402_58	196162.Noca_1707	0.0008446	50.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4DS64@85009|Propionibacteriales	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_2608402_26	478741.JAFS01000001_gene1393	9.045e-54	203.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia,37GJA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158535_k127_2608402_47	744980.TRICHSKD4_3186	7.212e-15	81.0	COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158535_k127_2608402_51	326427.Cagg_1111	2.038e-09	59.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,375XV@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ornithine cyclodeaminase mu-crystallin	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158535_k127_2608763_9	485913.Krac_9957	4.283e-61	220.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158535_k127_2608763_19	370438.PTH_1098	1.644e-11	77.0	COG1434@1|root,COG1434@2|Bacteria,1VB45@1239|Firmicutes,24RV0@186801|Clostridia,262UT@186807|Peptococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158535_k127_2608763_7	469383.Cwoe_5315	1.593e-66	237.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158535_k127_2608763_0	555779.Dthio_PD0863	4.534e-233	748.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158535_k127_2608763_5	330214.NIDE3441	2.452e-96	334.0	COG0305@1|root,COG0305@2|Bacteria,3J0EZ@40117|Nitrospirae	40117|Nitrospirae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158535_k127_2608763_15	68223.JNZY01000002_gene5143	1.756e-25	115.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158535_k127_2608763_14	756499.Desde_4229	1.793e-30	128.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,26287@186807|Peptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158535_k127_2608763_17	477974.Daud_0597	1.78e-15	83.0	COG3339@1|root,COG3339@2|Bacteria,1UDER@1239|Firmicutes,25I4F@186801|Clostridia,2667H@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158535_k127_2608763_13	1128421.JAGA01000002_gene611	1.175e-31	136.0	COG0668@1|root,COG0668@2|Bacteria,2NPVN@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
SRR25158535_k127_2608763_11	1286171.EAL2_c12920	5.899e-46	173.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25VX6@186806|Eubacteriaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158535_k127_2608763_8	1144275.COCOR_05823	1.742e-63	232.0	COG3214@1|root,COG3214@2|Bacteria,1R9AI@1224|Proteobacteria	1224|Proteobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_2608763_4	290397.Adeh_0141	1.813e-110	372.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158535_k127_2608763_18	243164.DET0363	1.482e-12	70.0	2A4G3@1|root,30T26@2|Bacteria,2GAY4@200795|Chloroflexi,34DJS@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2608763_12	1121946.AUAX01000023_gene4167	3.613e-39	147.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DFDP@85008|Micromonosporales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158535_k127_2608763_1	1306174.JODP01000004_gene978	1.898e-203	667.0	COG2909@1|root,COG2909@2|Bacteria,2IBVA@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_2608763_20	1116369.KB890024_gene70	2.358e-09	65.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	y2-aiiA	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158535_k127_2608763_2	298655.KI912266_gene1102	2.239e-170	573.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_2608763_10	37919.EP51_22500	4.992e-60	219.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4FXXH@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2608763_16	869210.Marky_0753	7.834e-19	97.0	COG1430@1|root,COG1430@2|Bacteria,1WJRZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158535_k127_2608763_6	347834.RHE_CH03584	2.903e-67	243.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TTSX@28211|Alphaproteobacteria,4B99J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
SRR25158535_k127_2608763_3	1122138.AQUZ01000017_gene6541	9.657e-124	413.0	COG3333@1|root,COG3333@2|Bacteria,2GJB2@201174|Actinobacteria,4DMZH@85009|Propionibacteriales	201174|Actinobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
SRR25158535_k127_26334_7	1385518.N798_15465	5.671e-26	112.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FIIB@85021|Intrasporangiaceae	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_26334_2	1122915.AUGY01000106_gene1328	3.948e-103	348.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,26QTF@186822|Paenibacillaceae	91061|Bacilli	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158535_k127_26334_1	1122915.AUGY01000106_gene1329	6.205e-114	386.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,274ZY@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158535_k127_26334_4	1499967.BAYZ01000155_gene610	5.305e-66	239.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158535_k127_26334_3	266117.Rxyl_1717	3.769e-78	284.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4CPJB@84995|Rubrobacteria	84995|Rubrobacteria	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158535_k127_26334_0	266117.Rxyl_1718	2.289e-262	825.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4CPQQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_26334_6	287986.DV20_15080	3.632e-61	221.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4E0PV@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158535_k127_26334_5	1440053.JOEI01000004_gene3934	8.553e-66	248.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM PfkB domain protein	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_2639102_5	1170562.Cal6303_5524	3.098e-90	312.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria	1117|Cyanobacteria	E	'ABC-type branched-chain amino acid transport	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
SRR25158535_k127_2639102_19	1122917.KB899659_gene5469	1.721e-07	66.0	COG4886@1|root,COG4886@2|Bacteria,1VJSM@1239|Firmicutes,4HQXJ@91061|Bacilli,26WXW@186822|Paenibacillaceae	91061|Bacilli	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2639102_1	945713.IALB_2612	2.217e-153	503.0	COG0423@1|root,COG0423@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
SRR25158535_k127_2639102_11	479434.Sthe_0953	9.021e-58	213.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,27YAT@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158535_k127_2639102_9	485913.Krac_7668	1.58e-66	240.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158535_k127_2639102_21	1380354.JIAN01000007_gene249	2.775e-05	53.0	COG3428@1|root,COG3428@2|Bacteria,2IA1C@201174|Actinobacteria,4F1DF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158535_k127_2639102_17	312309.VF_1352	2.399e-11	69.0	COG0494@1|root,COG0494@2|Bacteria,1RKVK@1224|Proteobacteria,1S86R@1236|Gammaproteobacteria,1XX6U@135623|Vibrionales	135623|Vibrionales	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158535_k127_2639102_4	436229.JOEH01000008_gene4125	3.352e-92	323.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria,2NFE1@228398|Streptacidiphilus	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158535_k127_2639102_13	1449126.JQKL01000073_gene3042	2.733e-40	169.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,268ZJ@186813|unclassified Clostridiales	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158535_k127_2639102_8	748449.Halha_1884	1.814e-67	251.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158535_k127_2639102_2	926569.ANT_08650	1.208e-130	430.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
SRR25158535_k127_2639102_14	1120972.AUMH01000013_gene2455	9.346e-36	154.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,277ZR@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
SRR25158535_k127_2639102_10	1382306.JNIM01000001_gene108	5.221e-60	217.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158535_k127_2639102_20	1382306.JNIM01000001_gene3477	7.46e-06	58.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	rlpA	-	3.5.1.104	ko:K03642,ko:K03791,ko:K22278	-	-	-	-	ko00000,ko01000	-	GH19	-	3D,DPBB_1,Hydrolase_2,LysM
SRR25158535_k127_2639102_3	383372.Rcas_3437	3.612e-97	342.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi,3758I@32061|Chloroflexia	32061|Chloroflexia	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
SRR25158535_k127_2639102_7	867903.ThesuDRAFT_02308	1.151e-74	276.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158535_k127_2639102_12	765420.OSCT_2335	1.312e-44	178.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,376RN@32061|Chloroflexia	32061|Chloroflexia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158535_k127_2639102_15	485913.Krac_8748	1.805e-25	123.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158535_k127_2639102_0	357808.RoseRS_4064	4.73e-210	671.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi,374VE@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158535_k127_2639102_16	1120948.KB903229_gene5149	9.174e-18	87.0	2EC2R@1|root,3361R@2|Bacteria,2GQ6U@201174|Actinobacteria,4EC4Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158535_k127_2639102_6	224911.27355976	3.598e-89	301.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158535_k127_26694_3	1111479.AXAR01000008_gene2281	1.266e-21	98.0	COG1611@1|root,COG1611@2|Bacteria,1V2D7@1239|Firmicutes,4HF8E@91061|Bacilli	91061|Bacilli	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158535_k127_26694_2	1304880.JAGB01000001_gene276	2.666e-67	244.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158535_k127_26694_1	264732.Moth_0877	9.587e-103	348.0	COG4012@1|root,COG4012@2|Bacteria,1TPF3@1239|Firmicutes,24E9V@186801|Clostridia,42HQR@68295|Thermoanaerobacterales	186801|Clostridia	H	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
SRR25158535_k127_26694_0	1128421.JAGA01000004_gene2560	3.333e-117	393.0	COG2252@1|root,COG2252@2|Bacteria,2NNZ2@2323|unclassified Bacteria	2|Bacteria	S	Permease family	yjcD	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158535_k127_26694_4	153948.NAL212_0962	2.636e-06	53.0	COG2304@1|root,COG2304@2|Bacteria,1PE8B@1224|Proteobacteria,2WC99@28216|Betaproteobacteria,374H0@32003|Nitrosomonadales	28216|Betaproteobacteria	S	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158535_k127_2682754_16	1449353.JQMQ01000005_gene5381	1.155e-05	52.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,2NJMU@228398|Streptacidiphilus	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158535_k127_2682754_5	526227.Mesil_0723	1.458e-60	222.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,1WJYD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_2682754_8	706587.Desti_2107	7.016e-50	188.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,2MSBX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158535_k127_2682754_7	479434.Sthe_0937	5.785e-53	194.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,27YBT@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158535_k127_2682754_14	1122933.JNIY01000003_gene142	2.182e-18	89.0	2E63U@1|root,330SV@2|Bacteria,2GSXM@201174|Actinobacteria,4F2VH@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2682754_11	1463821.JOGR01000001_gene1376	1.792e-32	139.0	COG2227@1|root,COG2227@2|Bacteria,2I8GJ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_2682754_2	266117.Rxyl_0619	3.438e-90	309.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_2682754_18	1449058.JQKT01000007_gene1367	6.017e-05	53.0	COG2267@1|root,COG2267@2|Bacteria,2IFQE@201174|Actinobacteria,4FRY6@85023|Microbacteriaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158535_k127_2682754_20	1449126.JQKL01000042_gene1035	0.0007702	51.0	COG1396@1|root,COG1396@2|Bacteria,1V0UH@1239|Firmicutes,24F2M@186801|Clostridia	186801|Clostridia	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158535_k127_2682754_4	1128421.JAGA01000003_gene2737	3.935e-82	289.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_2682754_6	485913.Krac_11442	5.698e-60	216.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158535_k127_2682754_10	309801.trd_1338	5.035e-43	167.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SRR25158535_k127_2682754_0	383372.Rcas_2438	4.1e-112	387.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_2682754_9	383372.Rcas_2439	1.905e-48	186.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2682754_12	485913.Krac_10933	9.743e-26	111.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_2682754_3	1304875.JAFZ01000001_gene691	2.098e-84	289.0	COG3643@1|root,COG3643@2|Bacteria,3T9TJ@508458|Synergistetes	2|Bacteria	E	TIGRFAM glutamate formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR25158535_k127_2682754_1	1121468.AUBR01000045_gene1802	1.644e-95	327.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158535_k127_2682754_17	745310.G432_17560	1.26e-05	52.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158535_k127_2682754_13	319003.Bra1253DRAFT_04807	2.299e-19	98.0	COG0596@1|root,COG0596@2|Bacteria,1Q4C8@1224|Proteobacteria,2TTW5@28211|Alphaproteobacteria,3JTEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	MA20_23630	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_2714188_24	1144275.COCOR_02582	4.623e-48	190.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,42PF4@68525|delta/epsilon subdivisions,2WKA8@28221|Deltaproteobacteria,2YUXB@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp70 protein	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
SRR25158535_k127_2714188_12	1155718.KB891889_gene6874	1.155e-82	300.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2714188_49	1385520.N802_07880	4.659e-20	98.0	2DQQK@1|root,33842@2|Bacteria,2H10K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_2714188_47	1048339.KB913029_gene3649	3.37e-22	105.0	29YC4@1|root,30K6H@2|Bacteria,2H0Z2@201174|Actinobacteria,4EX06@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2714188_13	1463926.JOCA01000002_gene5637	9.539e-82	278.0	COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
SRR25158535_k127_2714188_31	1463926.JOCA01000002_gene5636	2.821e-43	175.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158535_k127_2714188_32	1382306.JNIM01000001_gene284	1.129e-41	172.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158535_k127_2714188_30	1382306.JNIM01000001_gene936	2.072e-44	173.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Hemerythrin,Rieske
SRR25158535_k127_2714188_7	390989.JOEG01000013_gene2562	6.654e-95	322.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158535_k127_2714188_9	862751.SACTE_5876	1e-88	304.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158535_k127_2714188_58	471854.Dfer_3479	3.58e-10	70.0	COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia	976|Bacteroidetes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158535_k127_2714188_25	316274.Haur_0094	9.15e-47	181.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi,37661@32061|Chloroflexia	32061|Chloroflexia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRR25158535_k127_2714188_55	1394178.AWOO02000056_gene777	1.318e-11	70.0	COG0500@1|root,COG2226@2|Bacteria,2I1M7@201174|Actinobacteria,4EKZU@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_2714188_15	378806.STAUR_8383	6.41e-79	278.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42QKD@68525|delta/epsilon subdivisions,2WVK9@28221|Deltaproteobacteria,2YV9B@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158535_k127_2714188_11	1382306.JNIM01000001_gene3601	7.685e-86	300.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G5VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158535_k127_2714188_43	404589.Anae109_0752	7.99e-28	125.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158535_k127_2714188_45	477641.MODMU_0803	3.526e-26	113.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158535_k127_2714188_51	1131730.BAVI_02199	2.935e-17	88.0	COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,1ZQQT@1386|Bacillus	91061|Bacilli	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158535_k127_2714188_20	446470.Snas_1849	7.068e-52	198.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4EXXJ@85014|Glycomycetales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2714188_26	342949.PNA2_0176	2.212e-46	172.0	COG0663@1|root,arCOG01849@2157|Archaea,2XXXX@28890|Euryarchaeota,2439Z@183968|Thermococci	183968|Thermococci	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158535_k127_2714188_3	251221.35213636	6.086e-139	467.0	COG2986@1|root,COG2986@2|Bacteria,1G3FJ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.24,4.3.1.3	ko:K01745,ko:K10775	ko00340,ko00360,ko00940,ko01100,ko01110,map00340,map00360,map00940,map01100,map01110	M00039,M00045,M00137,M00350	R00697,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158535_k127_2714188_0	266117.Rxyl_0583	5.046e-251	784.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158535_k127_2714188_38	1540221.JQNI01000004_gene136	1.443e-34	152.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2714188_17	471853.Bcav_3506	2.031e-64	237.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158535_k127_2714188_54	266264.Rmet_4406	6.056e-12	74.0	COG3369@1|root,COG3369@2|Bacteria,1NMEB@1224|Proteobacteria,2VXWW@28216|Betaproteobacteria,1K9XN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158535_k127_2714188_5	1380393.JHVP01000001_gene2285	1.096e-108	372.0	COG1228@1|root,COG1228@2|Bacteria,2IE2S@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2714188_33	1382356.JQMP01000001_gene1264	4.165e-40	161.0	COG0717@1|root,COG0717@2|Bacteria,2G8PG@200795|Chloroflexi,27YDB@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158535_k127_2714188_27	1304872.JAGC01000003_gene2861	4.918e-46	181.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2MAJU@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_2714188_14	383372.Rcas_4417	1.562e-79	284.0	COG2358@1|root,COG2358@2|Bacteria,2G9YX@200795|Chloroflexi,377E1@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158535_k127_2714188_1	644966.Tmar_2101	2.383e-167	555.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia	186801|Clostridia	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158535_k127_2714188_37	479434.Sthe_1779	1.302e-37	160.0	COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia	189775|Thermomicrobia	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRR25158535_k127_2714188_2	525904.Tter_2684	4.458e-160	511.0	COG2141@1|root,COG2141@2|Bacteria,2NQKB@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2714188_35	1463854.JOHT01000009_gene1465	9.572e-39	158.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158535_k127_2714188_16	318424.EU78_08800	2.872e-66	237.0	COG0657@1|root,COG0741@1|root,COG0657@2|Bacteria,COG0741@2|Bacteria,2IBCH@201174|Actinobacteria,2359I@1762|Mycobacteriaceae	201174|Actinobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
SRR25158535_k127_2714188_34	536019.Mesop_2880	6.937e-40	162.0	COG2764@1|root,COG2764@2|Bacteria,1NY20@1224|Proteobacteria,2UTEI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2714188_22	521011.Mpal_2558	5.605e-51	186.0	COG0693@1|root,arCOG00769@2157|Archaea,2XTPH@28890|Euryarchaeota,2N9UJ@224756|Methanomicrobia	224756|Methanomicrobia	O	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158535_k127_2714188_23	1036674.A28LD_0828	5.674e-50	182.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,2QG6T@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	SelR domain	msrB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033743,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	iAF1260.b1778,iB21_1397.B21_01735,iBWG_1329.BWG_1591,iE2348C_1286.E2348C_1905,iEC042_1314.EC042_1944,iEC55989_1330.EC55989_1947,iECBD_1354.ECBD_1866,iECB_1328.ECB_01747,iECDH10B_1368.ECDH10B_1916,iECDH1ME8569_1439.ECDH1ME8569_1722,iECD_1391.ECD_01747,iECH74115_1262.ECH74115_2502,iECIAI39_1322.ECIAI39_1275,iECNA114_1301.ECNA114_1824,iECO103_1326.ECO103_1964,iECP_1309.ECP_1726,iECSE_1348.ECSE_1949,iECSF_1327.ECSF_1639,iECSP_1301.ECSP_2350,iECUMN_1333.ECUMN_2067,iECW_1372.ECW_m1947,iECs_1301.ECs2487,iEKO11_1354.EKO11_1997,iETEC_1333.ETEC_1810,iEcDH1_1363.EcDH1_1864,iEcE24377_1341.EcE24377A_2002,iEcSMS35_1347.EcSMS35_1413,iG2583_1286.G2583_2225,iJO1366.b1778,iLF82_1304.LF82_1402,iNRG857_1313.NRG857_08905,iPC815.YPO2158,iSSON_1240.SSON_1385,iWFL_1372.ECW_m1947,iY75_1357.Y75_RS09320,iYL1228.KPN_01198,iZ_1308.Z2817	SelR
SRR25158535_k127_2714188_36	469383.Cwoe_3355	1.016e-38	154.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_2714188_39	469383.Cwoe_5380	3.766e-34	146.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4CSXA@84995|Rubrobacteria	84995|Rubrobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_2714188_41	1283284.AZUK01000001_gene2506	6.333e-32	134.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,1Y4FK@135624|Aeromonadales	135624|Aeromonadales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2714188_48	298655.KI912266_gene648	4.051e-22	113.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158535_k127_2714188_57	926554.KI912671_gene317	5.234e-11	69.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	3.1.1.45	ko:K01061,ko:K15945	ko00361,ko00364,ko00623,ko01057,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01057,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222,R09330	RC00046,RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	SnoaL,SnoaL_2
SRR25158535_k127_2714188_52	1112274.KI911560_gene1514	4.212e-13	74.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2VVQ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158535_k127_2714188_42	1380390.JIAT01000009_gene943	8.376e-30	131.0	COG0607@1|root,COG0607@2|Bacteria,2IKTC@201174|Actinobacteria,4CQJC@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158535_k127_2714188_53	450851.PHZ_c0281	4.346e-13	80.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,2KHJ5@204458|Caulobacterales	204458|Caulobacterales	S	Molybdopterin	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158535_k127_2714188_59	1230476.C207_02620	1.748e-07	61.0	COG2010@1|root,COG2010@2|Bacteria,1NK3D@1224|Proteobacteria,2UN55@28211|Alphaproteobacteria,3K3Y7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158535_k127_2714188_61	290397.Adeh_2631	0.0005406	53.0	COG0437@1|root,COG2864@1|root,COG0437@2|Bacteria,COG2864@2|Bacteria,1MU1B@1224|Proteobacteria,42M6H@68525|delta/epsilon subdivisions,2WNDN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin	-	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4
SRR25158535_k127_2714188_50	469610.HMPREF0189_01809	1.543e-18	100.0	COG0437@1|root,COG0437@2|Bacteria,1QYZB@1224|Proteobacteria	1224|Proteobacteria	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
SRR25158535_k127_2714188_18	335543.Sfum_2511	2.49e-63	229.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2MQZF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_2714188_4	706587.Desti_3922	1.709e-112	394.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158535_k127_2714188_21	1382306.JNIM01000001_gene1022	2.067e-51	193.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_2714188_60	156889.Mmc1_1619	0.0001148	54.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_2714188_19	478801.Ksed_19270	1.809e-61	233.0	COG0659@1|root,COG0659@2|Bacteria,2H1V9@201174|Actinobacteria	201174|Actinobacteria	P	Molybdate transporter of MFS superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_MOT1
SRR25158535_k127_2714188_44	671143.DAMO_2439	5.227e-27	119.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158535_k127_2714188_40	138119.DSY0867	6.389e-34	143.0	COG1192@1|root,COG1192@2|Bacteria,1UI78@1239|Firmicutes,25ECF@186801|Clostridia	186801|Clostridia	D	Involved in chromosome partitioning	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2714188_8	138119.DSY0869	7.939e-91	308.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,261MU@186807|Peptococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
SRR25158535_k127_2714188_29	1121946.AUAX01000016_gene4769	1.94e-44	171.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2714188_46	1171373.PACID_15000	6.032e-26	111.0	COG1433@1|root,COG1433@2|Bacteria,2GSU0@201174|Actinobacteria	201174|Actinobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
SRR25158535_k127_2714188_6	240016.ABIZ01000001_gene2211	1.749e-98	341.0	COG0438@1|root,COG0438@2|Bacteria,46TGQ@74201|Verrucomicrobia,2IVD7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2714188_10	1048834.TC41_0434	1.299e-86	316.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,4HAUT@91061|Bacilli	91061|Bacilli	G	Glycosidase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
SRR25158535_k127_2714188_28	525904.Tter_1200	3.036e-45	188.0	COG1331@1|root,COG1331@2|Bacteria,2NPT4@2323|unclassified Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	DUF4861
SRR25158535_k127_2714188_56	335541.Swol_1899	4.425e-11	67.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
SRR25158535_k127_275139_19	926554.KI912672_gene67	4.25e-15	80.0	2CRSQ@1|root,32SPK@2|Bacteria	2|Bacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158535_k127_275139_23	326427.Cagg_3664	0.0004005	46.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia	32061|Chloroflexia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
SRR25158535_k127_275139_16	1313172.YM304_36660	1.097e-35	139.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria	201174|Actinobacteria	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158535_k127_275139_9	357808.RoseRS_0964	4.036e-84	291.0	COG0665@1|root,COG0665@2|Bacteria,2G867@200795|Chloroflexi,376MJ@32061|Chloroflexia	32061|Chloroflexia	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_275139_14	1128421.JAGA01000002_gene855	1.28e-47	175.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_275139_22	1211815.CBYP010000068_gene188	2.43e-08	67.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,4EVQR@85013|Frankiales	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158535_k127_275139_18	190650.CC_3417	2.891e-24	109.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158535_k127_275139_10	479434.Sthe_2315	1.788e-78	279.0	COG2855@1|root,COG2855@2|Bacteria,2G98G@200795|Chloroflexi	200795|Chloroflexi	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
SRR25158535_k127_275139_11	794846.AJQU01000063_gene2749	4.554e-71	274.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_275139_20	443218.AS9A_2759	1.07e-11	69.0	COG3324@1|root,COG3324@2|Bacteria,2I48G@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_275139_0	525904.Tter_0979	3.621e-138	454.0	COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528,iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
SRR25158535_k127_275139_8	1051632.TPY_1815	3.059e-90	314.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	iSDY_1059.SDY_4061	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_275139_2	309799.DICTH_0511	3.731e-123	414.0	COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria	2|Bacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
SRR25158535_k127_275139_4	497964.CfE428DRAFT_6224	1.582e-113	393.0	COG1384@1|root,COG1384@2|Bacteria	2|Bacteria	J	tRNA binding	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158535_k127_275139_15	635013.TherJR_0229	1.549e-43	164.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,261HN@186807|Peptococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158535_k127_275139_12	469383.Cwoe_2876	1.187e-64	230.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CQT2@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158535_k127_275139_21	1123321.KB905827_gene497	2.089e-08	67.0	COG4334@1|root,COG4334@2|Bacteria	2|Bacteria	E	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255,F420H2_quin_red
SRR25158535_k127_275139_13	1382356.JQMP01000001_gene1193	3.876e-50	195.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158535_k127_275139_5	479434.Sthe_2769	1.603e-108	365.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158535_k127_275139_3	309801.trd_1373	1.28e-113	396.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi,27Y1G@189775|Thermomicrobia	189775|Thermomicrobia	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158535_k127_275139_6	479434.Sthe_1347	9.4e-108	379.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_275139_17	649638.Trad_1757	5.827e-32	141.0	COG1246@1|root,COG1246@2|Bacteria,1WI5N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158535_k127_275139_1	1121468.AUBR01000010_gene2467	2.515e-129	440.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,42F08@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158535_k127_275139_7	237368.SCABRO_02995	7.381e-95	318.0	COG0137@1|root,COG0137@2|Bacteria,2IX1G@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158535_k127_2810236_18	795797.C497_16127	9.165e-50	199.0	COG1234@1|root,arCOG00500@2157|Archaea	2157|Archaea	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158535_k127_2810236_7	1206101.AZXC01000008_gene3161	7.18e-86	302.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_2810236_21	1463856.JOHY01000002_gene1119	1.758e-46	177.0	COG1011@1|root,COG1011@2|Bacteria,2GN5U@201174|Actinobacteria	201174|Actinobacteria	S	haloacid dehalogenase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158535_k127_2810236_0	357808.RoseRS_0100	2.745e-273	856.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi,3757V@32061|Chloroflexia	32061|Chloroflexia	T	elongation factor Tu domain 2 protein	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158535_k127_2810236_5	1278073.MYSTI_03446	9.209e-121	401.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158535_k127_2810236_31	1298598.JCM21714_36	8.343e-20	105.0	COG0697@1|root,COG0697@2|Bacteria,1V0DI@1239|Firmicutes,4HD1I@91061|Bacilli,471P4@74385|Gracilibacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2810236_19	383372.Rcas_3281	4.274e-49	194.0	COG1089@1|root,COG1089@2|Bacteria,2G6AN@200795|Chloroflexi,3755V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158535_k127_2810236_3	1128421.JAGA01000004_gene2629	3.167e-133	447.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_2810236_10	760568.Desku_3301	4.559e-72	272.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158535_k127_2810236_30	748247.AZKH_p0139	1.228e-20	107.0	COG1051@1|root,COG1051@2|Bacteria,1QVI6@1224|Proteobacteria,2WGSD@28216|Betaproteobacteria,2KY2Q@206389|Rhodocyclales	206389|Rhodocyclales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_2810236_25	35754.JNYJ01000005_gene5574	1.033e-34	138.0	COG0251@1|root,COG0251@2|Bacteria,2II9B@201174|Actinobacteria,4DFW9@85008|Micromonosporales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_2810236_32	326427.Cagg_2739	2.056e-19	93.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,375YA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2810236_13	671143.DAMO_2082	2.218e-62	226.0	COG0614@1|root,COG0614@2|Bacteria,2NPHH@2323|unclassified Bacteria	2|Bacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158535_k127_2810236_14	1382306.JNIM01000001_gene1578	1.111e-57	216.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158535_k127_2810236_15	292459.STH1933	6.932e-57	220.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia	186801|Clostridia	HP	Abc transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158535_k127_2810236_27	1321778.HMPREF1982_00716	9.807e-29	131.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158535_k127_2810236_11	243231.GSU1523	1.168e-70	249.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158535_k127_2810236_24	357808.RoseRS_3715	4.284e-37	154.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158535_k127_2810236_4	997346.HMPREF9374_0152	2.945e-121	398.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,27AV4@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06615,iYO844.BSU32250	PALP
SRR25158535_k127_2810236_16	479434.Sthe_1458	2.23e-55	207.0	COG0083@1|root,COG0083@2|Bacteria,2G6MP@200795|Chloroflexi,27Y5U@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158535_k127_2810236_26	1293048.CBMB010000004_gene2372	1.116e-33	149.0	COG0340@1|root,COG3398@1|root,arCOG01940@2157|Archaea,arCOG02611@2157|Archaea,2XSZ5@28890|Euryarchaeota,23ST2@183963|Halobacteria	183963|Halobacteria	H	COG1654 Biotin operon repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158535_k127_2810236_22	292459.STH1449	1.359e-44	177.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158535_k127_2810236_8	443144.GM21_0896	8.466e-86	309.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WP9B@28221|Deltaproteobacteria,43U3E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158535_k127_2810236_9	1122223.KB890698_gene986	3.077e-83	300.0	COG0825@1|root,COG0825@2|Bacteria,1WJ82@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158535_k127_2810236_35	498848.TaqDRAFT_3437	1.649e-07	64.0	COG0511@1|root,COG0511@2|Bacteria,1WJNN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158535_k127_2810236_36	408672.NBCG_04821	6.7e-07	61.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria,4DSIG@85009|Propionibacteriales	201174|Actinobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_2810236_34	1236959.BAMT01000001_gene1153	2.257e-10	72.0	2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria,2W5R6@28216|Betaproteobacteria,2KN9M@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2810236_12	760568.Desku_2295	1.331e-68	243.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,260H7@186807|Peptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158535_k127_2810236_1	1121468.AUBR01000002_gene669	6.349e-166	537.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,42F16@68295|Thermoanaerobacterales	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158535_k127_2810236_23	326427.Cagg_1905	4.854e-41	157.0	COG0764@1|root,COG0764@2|Bacteria,2G8P4@200795|Chloroflexi,375PF@32061|Chloroflexia	32061|Chloroflexia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158535_k127_2810236_6	1382304.JNIL01000001_gene1753	8.015e-88	298.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,2784I@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the arginase family	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158535_k127_2810236_33	66869.JNXG01000023_gene2861	2.74e-11	73.0	COG1595@1|root,COG1595@2|Bacteria,2II9Z@201174|Actinobacteria,41CQ2@629295|Streptomyces griseus group	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_2810236_17	546414.Deide_16680	6.989e-51	188.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158535_k127_2810236_28	1122604.JONR01000003_gene1384	1.163e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,1NIQA@1224|Proteobacteria,1SSAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158535_k127_2810236_2	1347368.HG964403_gene4401	7.503e-153	497.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
SRR25158535_k127_2810236_29	1234364.AMSF01000053_gene1320	8.577e-22	100.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1X67R@135614|Xanthomonadales	135614|Xanthomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158535_k127_2810236_20	937777.Deipe_2193	1.076e-48	183.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	aadD	-	-	ko:K17882	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	KNTase_C,NTP_transf_2
SRR25158535_k127_284448_6	709986.Deima_2614	1.166e-21	111.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
SRR25158535_k127_284448_5	1340493.JNIF01000003_gene1807	2.798e-37	160.0	COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria	57723|Acidobacteria	H	PFAM delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158535_k127_284448_2	309801.trd_1505	8.64e-98	336.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158535_k127_284448_4	926550.CLDAP_08620	3.499e-44	181.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158535_k127_284448_8	1266909.AUAG01000032_gene2403	3.759e-05	57.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWIH@135613|Chromatiales	135613|Chromatiales	CP	PFAM NADH Ubiquinone plastoquinone	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158535_k127_284448_1	1128421.JAGA01000002_gene1326	5.859e-113	381.0	COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma-54 factor	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158535_k127_284448_0	525904.Tter_0081	3.179e-261	824.0	COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria	2|Bacteria	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158535_k127_284448_3	306281.AJLK01000104_gene5762	4.382e-78	270.0	COG1028@1|root,COG1028@2|Bacteria,1GK5E@1117|Cyanobacteria,1JKF5@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_284448_7	1223542.GM1_007_00980	1.229e-06	52.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4GAT8@85026|Gordoniaceae	201174|Actinobacteria	S	LamB/YcsF family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158535_k127_2847616_0	58123.JOFJ01000001_gene3038	2.524e-83	291.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4EG2K@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_2847616_1	1356854.N007_02840	3.253e-73	267.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,2785S@186823|Alicyclobacillaceae	91061|Bacilli	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158535_k127_2847616_2	1089553.Tph_c13150	2.727e-60	229.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,42EYR@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158535_k127_2847616_4	765420.OSCT_2786	0.0001034	53.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,375TM@32061|Chloroflexia	32061|Chloroflexia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158535_k127_2847616_3	1487923.DP73_07180	8.711e-32	126.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,24N58@186801|Clostridia,2628B@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158535_k127_2847616_5	1380393.JHVP01000013_gene3410	0.0001648	50.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4ES94@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158535_k127_2862430_42	35754.JNYJ01000006_gene5224	2.128e-19	103.0	COG5662@1|root,COG5662@2|Bacteria,2GN1B@201174|Actinobacteria,4DBXN@85008|Micromonosporales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2862430_36	479431.Namu_3413	1.222e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2IG6R@201174|Actinobacteria,4ESVZ@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2862430_39	448385.sce3169	1.365e-23	117.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2862430_31	1242864.D187_009202	6.703e-44	181.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158535_k127_2862430_20	266117.Rxyl_2862	6.353e-97	329.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CSW8@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158535_k127_2862430_47	1504319.GM45_0125	5.004e-11	76.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,3UWRY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2862430_34	864563.HMPREF9166_0697	3.526e-37	159.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4H27I@909932|Negativicutes	909932|Negativicutes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158535_k127_2862430_35	1449347.JQLN01000005_gene5267	7.446e-36	143.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,2M0Z0@2063|Kitasatospora	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2862430_45	796606.BMMGA3_15750	1.141e-12	81.0	COG0793@1|root,COG0793@2|Bacteria,1V0GW@1239|Firmicutes,4HA53@91061|Bacilli,1ZC9X@1386|Bacillus	91061|Bacilli	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_5,PDZ,PDZ_2,Peptidase_S41
SRR25158535_k127_2862430_5	1254432.SCE1572_23125	3.243e-150	489.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158535_k127_2862430_51	243231.GSU1045	0.0002382	50.0	2CHSG@1|root,316CZ@2|Bacteria,1PXCU@1224|Proteobacteria,4308W@68525|delta/epsilon subdivisions,2WVAX@28221|Deltaproteobacteria,43V1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
SRR25158535_k127_2862430_43	926569.ANT_17320	7.361e-17	96.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2862430_50	32051.SynWH7803_0952	7.061e-06	56.0	COG0491@1|root,COG0491@2|Bacteria,1G3D1@1117|Cyanobacteria,1GYM7@1129|Synechococcus	1117|Cyanobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158535_k127_2862430_23	926554.KI912633_gene3985	4.403e-85	319.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1WKH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2862430_25	365528.KB891229_gene224	4.509e-74	271.0	COG0500@1|root,COG2226@2|Bacteria,2GKPQ@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_2862430_3	266117.Rxyl_2416	2.154e-172	559.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4CPWQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158535_k127_2862430_2	1242864.D187_001582	2.338e-199	631.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	LMF	-	-	-	-	-	-	-	-	-	-	-	LMF1
SRR25158535_k127_2862430_37	1027292.HMPREF9372_0048	1e-28	122.0	2CWCM@1|root,32SZF@2|Bacteria,1VC94@1239|Firmicutes,4HKNB@91061|Bacilli,26HTG@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
SRR25158535_k127_2862430_15	1408224.SAMCCGM7_c5591	3.978e-109	392.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_2862430_6	1382356.JQMP01000004_gene188	3.317e-146	479.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158535_k127_2862430_44	479434.Sthe_0747	1.061e-13	86.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2862430_24	525904.Tter_0396	8.999e-85	299.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2862430_53	1172180.KB911782_gene3980	0.000968	53.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3,PD40,TAT_signal
SRR25158535_k127_2862430_49	329726.AM1_2455	2.081e-08	63.0	COG1434@1|root,COG1434@2|Bacteria,1G1QC@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158535_k127_2862430_46	1300345.LF41_1416	1.174e-11	71.0	2E5FW@1|root,3307K@2|Bacteria,1R3G8@1224|Proteobacteria,1T67F@1236|Gammaproteobacteria,1X8M9@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158535_k127_2862430_4	525904.Tter_0901	1.01e-160	526.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2862430_16	926550.CLDAP_32100	1.184e-107	374.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_2862430_14	1382356.JQMP01000003_gene1706	2.772e-109	378.0	COG0444@1|root,COG0444@2|Bacteria,2G6CC@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_2862430_26	273068.TTE0226	2.251e-69	259.0	COG1173@1|root,COG1173@2|Bacteria,1UH0Y@1239|Firmicutes,24CHN@186801|Clostridia,42G5K@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_2862430_17	926550.CLDAP_32130	6.896e-107	360.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2862430_30	485913.Krac_2673	6.68e-44	183.0	COG0637@1|root,COG0637@2|Bacteria,2G8S9@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158535_k127_2862430_19	324602.Caur_0867	4.054e-101	371.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_2862430_12	298655.KI912266_gene1102	3.923e-119	420.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_2862430_7	518766.Rmar_2170	2.817e-145	480.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1FJ60@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158535_k127_2862430_38	1173025.GEI7407_3429	3.354e-26	122.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSJ@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158535_k127_2862430_11	1382356.JQMP01000004_gene541	3.418e-123	405.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158535_k127_2862430_29	1122917.KB899671_gene4389	1.259e-51	211.0	COG0471@1|root,COG0664@1|root,COG0471@2|Bacteria,COG0664@2|Bacteria,1U26G@1239|Firmicutes,4HEVG@91061|Bacilli	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp,cNMP_binding
SRR25158535_k127_2862430_48	1242864.D187_003822	6.354e-10	74.0	COG0664@1|root,COG0664@2|Bacteria,1QX5I@1224|Proteobacteria,43BY8@68525|delta/epsilon subdivisions,2X794@28221|Deltaproteobacteria,2YW6W@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_2862430_22	443144.GM21_1592	7.988e-87	296.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_2862430_18	1499967.BAYZ01000054_gene4817	1.455e-106	356.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2862430_10	1499967.BAYZ01000054_gene4816	3.395e-125	421.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2862430_40	710686.Mycsm_00032	3.532e-23	109.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,238WY@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_2862430_8	1385519.N801_15185	6.687e-135	453.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2GNPX@201174|Actinobacteria,4FFVN@85021|Intrasporangiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	osaB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2862430_33	1385519.N801_15190	8.001e-38	145.0	COG0745@1|root,COG0745@2|Bacteria,2IS52@201174|Actinobacteria,4FH4M@85021|Intrasporangiaceae	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2862430_0	1502851.FG93_00182	8.255e-265	885.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
SRR25158535_k127_2862430_28	33876.JNXY01000039_gene6583	4.236e-53	211.0	COG1994@1|root,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria,4DB7M@85008|Micromonosporales	201174|Actinobacteria	T	ATPase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
SRR25158535_k127_2862430_41	33876.JNXY01000039_gene6584	2.527e-20	91.0	28VCT@1|root,2ZHFH@2|Bacteria,2GPRW@201174|Actinobacteria,4DFCX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2862430_52	765420.OSCT_1111	0.0005873	52.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
SRR25158535_k127_2862430_32	1306174.JODP01000001_gene5350	8.916e-43	165.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_2862430_27	485913.Krac_2542	1.694e-60	220.0	COG2141@1|root,COG2141@2|Bacteria,2G8NG@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2862430_13	485913.Krac_11396	1.295e-111	370.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2862430_9	1463825.JNXC01000022_gene521	2.948e-131	423.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4DZ6D@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158535_k127_2862430_1	1205680.CAKO01000037_gene1210	1.711e-202	641.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JR7C@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the aldehyde dehydrogenase family	betB	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158535_k127_2862430_21	1121946.AUAX01000015_gene5958	6.646e-88	294.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4DBHJ@85008|Micromonosporales	201174|Actinobacteria	F	Amidohydrolase family	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158535_k127_2926012_0	1382356.JQMP01000003_gene2033	9.306e-143	470.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158535_k127_2926012_2	215803.DB30_2329	3.819e-99	355.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MV	MacB-like periplasmic core domain	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2926012_4	926569.ANT_27060	1.484e-74	264.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2926012_3	338966.Ppro_0432	3.08e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158535_k127_2926012_5	1380390.JIAT01000011_gene2542	5.376e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2926012_12	29306.JOBE01000017_gene1245	3.654e-11	73.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2926012_9	314345.SPV1_14254	4.853e-13	79.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria	1224|Proteobacteria	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158535_k127_2926012_1	861299.J421_0666	1.282e-99	336.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2926012_6	479432.Sros_4032	1.586e-31	145.0	COG1621@1|root,COG1621@2|Bacteria,2GKT1@201174|Actinobacteria,4EI57@85012|Streptosporangiales	201174|Actinobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2926012_7	378806.STAUR_0630	1.378e-19	93.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2926012_8	195250.CM001776_gene3034	1.368e-16	90.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1G1QG@1117|Cyanobacteria,1GYCP@1129|Synechococcus	1117|Cyanobacteria	MT	mechanosensitive	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SRR25158535_k127_2926012_11	1120956.JHZK01000017_gene2664	5.078e-12	74.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VCGZ@28211|Alphaproteobacteria,1JPIV@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158535_k127_2928813_9	696369.KI912183_gene703	3.918e-62	222.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,261AS@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158535_k127_2928813_0	479434.Sthe_0936	0.0	1313.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158535_k127_2928813_16	479434.Sthe_1631	4.778e-21	111.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2928813_10	469382.Hbor_06150	5.169e-60	232.0	COG0500@1|root,arCOG03411@2157|Archaea,2XWTI@28890|Euryarchaeota,23VGG@183963|Halobacteria	183963|Halobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158535_k127_2928813_13	552811.Dehly_0916	4.125e-44	182.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi,34D0J@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SRR25158535_k127_2928813_6	1321781.HMPREF1985_00260	3.36e-87	303.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4H2MP@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158535_k127_2928813_7	649638.Trad_1503	5.863e-69	250.0	COG3648@1|root,COG3648@2|Bacteria	2|Bacteria	Q	urate oxidase activity	pucL	-	1.7.3.3,4.1.1.97	ko:K00365,ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R06604,R07981	RC01551,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158535_k127_2928813_19	1123284.KB899045_gene2456	1.123e-07	62.0	COG3195@1|root,COG3195@2|Bacteria,1VB2S@1239|Firmicutes,4HM1Y@91061|Bacilli,26PZE@186821|Sporolactobacillaceae	91061|Bacilli	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K13485	ko00230,ko01100,map00230,map01100	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
SRR25158535_k127_2928813_15	1206735.BAGG01000115_gene4958	3.133e-23	102.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4G3GV@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158535_k127_2928813_12	1187851.A33M_4072	4.636e-48	179.0	COG2164@1|root,COG2164@2|Bacteria,1RCY5@1224|Proteobacteria,2U5NN@28211|Alphaproteobacteria,3FE5N@34008|Rhodovulum	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3830)	MA20_34860	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRR25158535_k127_2928813_4	1540221.JQNI01000004_gene283	1.281e-101	344.0	COG0044@1|root,COG0044@2|Bacteria,1WJQT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring	allB	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_2928813_5	293826.Amet_4572	2.344e-87	318.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,36FIQ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_2928813_8	1380393.JHVP01000011_gene3068	5.689e-68	240.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4EVZK@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_2928813_11	749927.AMED_1920	7.208e-52	211.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E2JM@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_2928813_17	118161.KB235922_gene2272	2.039e-09	69.0	COG3153@1|root,COG3153@2|Bacteria,1G9FX@1117|Cyanobacteria	1117|Cyanobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158535_k127_2928813_1	35754.JNYJ01000021_gene505	1.955e-269	854.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4D96N@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_2928813_3	471852.Tcur_4185	3.17e-124	432.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4EGXN@85012|Streptosporangiales	201174|Actinobacteria	F	Adenosine/AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158535_k127_2928813_18	1379270.AUXF01000002_gene1760	2.034e-08	68.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZU9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2928813_2	1303518.CCALI_02392	5.84e-218	700.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158535_k127_2928813_14	570952.ATVH01000015_gene1475	3.768e-25	109.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,2JSJ5@204441|Rhodospirillales	204441|Rhodospirillales	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158535_k127_2954404_29	1382356.JQMP01000001_gene1263	2.057e-06	49.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_2954404_22	1033810.HLPCO_000846	2.479e-24	120.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158535_k127_2954404_15	266117.Rxyl_1243	3.26e-46	185.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158535_k127_2954404_32	588581.Cpap_1812	0.0001377	55.0	2DUU6@1|root,33S9S@2|Bacteria,1VRCX@1239|Firmicutes,24EBM@186801|Clostridia,3WNVB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2954404_14	311424.DhcVS_1445	9.025e-47	192.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2954404_7	1121472.AQWN01000003_gene1462	2.61e-85	314.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,260PT@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_2954404_4	1125863.JAFN01000001_gene1676	3.9e-127	422.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_2954404_18	323259.Mhun_1526	1.285e-36	143.0	COG0432@1|root,arCOG04214@2157|Archaea,2XXSW@28890|Euryarchaeota,2NATS@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158535_k127_2954404_9	867903.ThesuDRAFT_00419	5.063e-75	265.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158535_k127_2954404_12	525904.Tter_1432	1.254e-54	202.0	COG2890@1|root,COG2890@2|Bacteria,2NPDN@2323|unclassified Bacteria	2|Bacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012	-	-	-	MTS
SRR25158535_k127_2954404_1	525897.Dbac_2687	5.487e-176	578.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2MA8W@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,BioW
SRR25158535_k127_2954404_3	1121406.JAEX01000005_gene2960	1.092e-148	496.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria,2MGBC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158535_k127_2954404_20	756272.Plabr_3042	1.563e-32	143.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158535_k127_2954404_24	1122915.AUGY01000001_gene6982	3.587e-16	89.0	COG2340@1|root,COG2340@2|Bacteria,1V959@1239|Firmicutes,4HQM7@91061|Bacilli,26W3R@186822|Paenibacillaceae	91061|Bacilli	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Cu_amine_oxidN1
SRR25158535_k127_2954404_11	479434.Sthe_1882	6.193e-56	207.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2954404_17	1382356.JQMP01000003_gene2404	2.278e-37	148.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,27Y7A@189775|Thermomicrobia	189775|Thermomicrobia	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158535_k127_2954404_16	596315.HMPREF0634_1558	3.412e-39	158.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25RC3@186804|Peptostreptococcaceae	186801|Clostridia	G	isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158535_k127_2954404_2	246194.CHY_2557	2.312e-167	544.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,42F68@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158535_k127_2954404_8	326427.Cagg_2169	1.364e-76	281.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi,3754Q@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158535_k127_2954404_10	1122921.KB898186_gene5221	4.528e-60	224.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,26SC1@186822|Paenibacillaceae	91061|Bacilli	M	transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158535_k127_2954404_6	710111.FraQA3DRAFT_4730	6.412e-93	315.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158535_k127_2954404_5	292459.STH2102	3.627e-120	407.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,25B1P@186801|Clostridia	186801|Clostridia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2954404_26	1246459.KB898359_gene2435	1.696e-10	69.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,2UBR2@28211|Alphaproteobacteria,4BES2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	small integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRR25158535_k127_2954404_31	398580.Dshi_0232	5.68e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,1NV5Z@1224|Proteobacteria,2URN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
SRR25158535_k127_2954404_33	1380390.JIAT01000010_gene4585	0.0006611	48.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158535_k127_2954404_25	1192034.CAP_8941	9.748e-15	88.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2954404_13	981369.JQMJ01000004_gene1000	9.748e-54	210.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,2NFCN@228398|Streptacidiphilus	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_2954404_19	1521187.JPIM01000031_gene2005	6.925e-33	138.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,376W7@32061|Chloroflexia	32061|Chloroflexia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158535_k127_2954404_27	908340.HMPREF9406_4273	1.775e-09	61.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,36MIS@31979|Clostridiaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158535_k127_2954404_28	580332.Slit_2985	1.376e-08	65.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,44VTQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158535_k127_2954404_23	518766.Rmar_0314	5.612e-17	93.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1FJFS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158535_k127_2954404_0	525904.Tter_0065	1.66e-220	695.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158535_k127_2954404_21	794903.OPIT5_11715	9.662e-32	130.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,3K742@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158535_k127_2971105_1	370438.PTH_2220	7.738e-69	249.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_2971105_5	1242864.D187_009345	1.256e-38	160.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
SRR25158535_k127_2971105_9	1347086.CCBA010000008_gene1226	9.202e-12	73.0	COG1372@1|root,COG1372@2|Bacteria,1VPYF@1239|Firmicutes,4HSTN@91061|Bacilli,1ZEPN@1386|Bacillus	91061|Bacilli	L	LAGLIDADG-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3
SRR25158535_k127_2971105_6	1125863.JAFN01000001_gene2094	1.045e-36	149.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158535_k127_2971105_8	292459.STH2398	4.008e-19	93.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRR25158535_k127_2971105_7	326427.Cagg_2227	4.539e-31	129.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2971105_10	1144275.COCOR_07347	8.953e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1Q350@1224|Proteobacteria,438VR@68525|delta/epsilon subdivisions,2X41C@28221|Deltaproteobacteria,2YXXD@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_2971105_0	1007103.AFHW01000048_gene3428	1.627e-193	645.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26QXQ@186822|Paenibacillaceae	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158535_k127_2971105_2	316274.Haur_1194	2.022e-59	218.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,376AI@32061|Chloroflexia	32061|Chloroflexia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_2971105_4	309801.trd_1035	1.139e-38	157.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi,27XGF@189775|Thermomicrobia	189775|Thermomicrobia	O	Sigma-54 interaction domain	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_2971105_3	1382356.JQMP01000003_gene2219	2.938e-52	195.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi,27XGF@189775|Thermomicrobia	189775|Thermomicrobia	O	Sigma-54 interaction domain	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_2973387_5	629773.AORY01000001_gene2004	6.466e-07	52.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K14F@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2973387_0	504832.OCAR_7523	4.882e-159	518.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2973387_1	1380394.JADL01000016_gene414	2.271e-124	405.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	nikB	-	-	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2973387_2	331869.BAL199_06624	2.972e-89	318.0	COG1173@1|root,COG1173@2|Bacteria,1PFAG@1224|Proteobacteria,2V8S7@28211|Alphaproteobacteria,4BS73@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_2973387_3	443255.SCLAV_p1180	1.159e-51	203.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158535_k127_2973387_6	1157632.AQWQ01000002_gene4826	5.367e-06	48.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158535_k127_2973387_4	987059.RBXJA2T_16217	3.928e-24	104.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,1KJ0W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158535_k127_2975954_3	1144310.PMI07_005449	1.625e-121	406.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA,TctB
SRR25158535_k127_2975954_26	944435.AXAJ01000001_gene74	2.542e-07	64.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1K17A@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA,TctB
SRR25158535_k127_2975954_18	525904.Tter_2774	1.434e-46	178.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	-
SRR25158535_k127_2975954_28	272134.KB731324_gene5159	3.669e-07	62.0	COG4423@1|root,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
SRR25158535_k127_2975954_24	429009.Adeg_0794	1.402e-11	76.0	COG1361@1|root,COG1361@2|Bacteria,1VPQQ@1239|Firmicutes,24WHC@186801|Clostridia,42HPA@68295|Thermoanaerobacterales	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2975954_0	76114.p2A120	1.934e-175	563.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158535_k127_2975954_23	429009.Adeg_0382	1.278e-13	78.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,42J0Y@68295|Thermoanaerobacterales	186801|Clostridia	S	flavin reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158535_k127_2975954_15	706587.Desti_0828	1.005e-64	235.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria,2MRKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158535_k127_2975954_17	591158.SSMG_03658	8.306e-50	197.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria	201174|Actinobacteria	G	Class II aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158535_k127_2975954_25	994479.GL877879_gene4568	2.333e-10	67.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4E3DV@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR25158535_k127_2975954_6	1120949.KB903314_gene304	2.868e-108	366.0	2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2975954_7	1120972.AUMH01000002_gene2762	6.182e-103	352.0	COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,4HAEM@91061|Bacilli	91061|Bacilli	E	ethanolamine utilization protein	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
SRR25158535_k127_2975954_11	1283283.ATXA01000006_gene1854	4.81e-68	245.0	COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria	201174|Actinobacteria	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2975954_2	591157.SSLG_00167	1.806e-134	439.0	2DWN2@1|root,3414B@2|Bacteria,2IC7M@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2975954_30	1104324.P186_0560	0.0006936	53.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,PUCC
SRR25158535_k127_2975954_8	312284.A20C1_08939	8.495e-103	361.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,3UXNV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
SRR25158535_k127_2975954_1	1131814.JAFO01000001_gene3485	2.029e-160	533.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_2975954_16	1122915.AUGY01000118_gene6523	4.031e-50	203.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_2975954_10	1121090.KB894689_gene333	1.413e-77	282.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158535_k127_2975954_19	1122915.AUGY01000118_gene6542	4.095e-46	186.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_2975954_12	1231391.AMZF01000003_gene3115	5.812e-68	244.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_2975954_22	43759.JNWK01000074_gene6391	8.811e-33	139.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158535_k127_2975954_20	861299.J421_6132	2.07e-42	171.0	COG0477@1|root,COG2814@2|Bacteria,1ZSUR@142182|Gemmatimonadetes	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_2975954_14	1122611.KB903973_gene2545	4.054e-65	241.0	COG2124@1|root,COG2124@2|Bacteria,2ICY7@201174|Actinobacteria	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158535_k127_2975954_5	477641.MODMU_1794	1.156e-116	389.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_2975954_21	485913.Krac_1828	2.92e-37	153.0	COG0596@1|root,COG0596@2|Bacteria,2G8Y9@200795|Chloroflexi	2|Bacteria	S	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158535_k127_2975954_27	298654.FraEuI1c_1247	3.243e-07	63.0	COG0715@1|root,COG0715@2|Bacteria,2GNMC@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158535_k127_2975954_9	469383.Cwoe_4099	1.008e-102	344.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2975954_4	1380386.JIAW01000030_gene3585	9.32e-117	387.0	COG3435@1|root,COG3435@2|Bacteria,2IE81@201174|Actinobacteria,236XY@1762|Mycobacteriaceae	201174|Actinobacteria	Q	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2975954_13	1380386.JIAW01000030_gene3586	2.079e-67	239.0	COG0464@1|root,COG0464@2|Bacteria,2IN7Z@201174|Actinobacteria	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158535_k127_2975954_29	700508.D174_09980	0.0002202	53.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,234ZV@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158535_k127_2994703_10	426114.THI_2752	4.346e-05	52.0	2E3Q3@1|root,32YN2@2|Bacteria,1NB4I@1224|Proteobacteria,2VWIB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2994703_3	555079.Toce_1429	3.086e-107	368.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,42EWF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	acoL	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_2994703_11	1121459.AQXE01000001_gene2840	0.0003067	53.0	COG0834@1|root,COG0834@2|Bacteria,1R4IH@1224|Proteobacteria,43ATK@68525|delta/epsilon subdivisions,2X67W@28221|Deltaproteobacteria,2MGYC@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158535_k127_2994703_7	479434.Sthe_1800	1.049e-48	189.0	COG0373@1|root,COG0373@2|Bacteria,2G5T4@200795|Chloroflexi,27YFY@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158535_k127_2994703_6	1089455.MOPEL_074_00240	1.445e-52	211.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4F619@85018|Dermatophilaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158535_k127_2994703_9	266117.Rxyl_1977	3.988e-09	68.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158535_k127_2994703_4	379066.GAU_2593	1.231e-101	351.0	COG0113@1|root,COG0113@2|Bacteria,1ZT4F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158535_k127_2994703_0	1382356.JQMP01000001_gene827	1.05e-154	505.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2994703_8	1303518.CCALI_00871	1.229e-41	175.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158535_k127_2994703_1	525904.Tter_2590	2.589e-127	426.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRR25158535_k127_2994703_5	1382306.JNIM01000001_gene3435	7.699e-81	297.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158535_k127_2994703_2	383372.Rcas_1840	1.109e-110	382.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_3008523_0	1304880.JAGB01000003_gene1295	4.05e-182	581.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	GDC-P
SRR25158535_k127_3008523_8	1537715.JQFJ01000002_gene1188	8.261e-25	121.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,2K27W@204457|Sphingomonadales	204457|Sphingomonadales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158535_k127_3008523_7	1128421.JAGA01000002_gene1099	4.641e-32	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_3008523_6	1510531.JQJJ01000008_gene3733	3.778e-32	145.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,3JW96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	MA20_01200	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_3008523_2	765420.OSCT_0588	2.333e-141	469.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,375R9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158535_k127_3008523_5	941824.TCEL_00927	9.385e-86	294.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36DBU@31979|Clostridiaceae	186801|Clostridia	P	Permease	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158535_k127_3008523_3	1128421.JAGA01000002_gene832	3.907e-94	320.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_3008523_1	1382356.JQMP01000004_gene645	7.058e-145	469.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,27XUE@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_3008523_4	765420.OSCT_0589	2.376e-92	316.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_3147163_5	1307761.L21SP2_1484	7.797e-60	211.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158535_k127_3147163_8	383372.Rcas_2260	1.115e-20	106.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,376BX@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158535_k127_3147163_12	552811.Dehly_0799	3.263e-09	70.0	COG0645@1|root,COG0645@2|Bacteria,2GBGC@200795|Chloroflexi,34CRH@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158535_k127_3147163_2	383372.Rcas_1233	2.95e-128	443.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi,375DT@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_3147163_6	555079.Toce_0288	3.938e-41	175.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia,42F0P@68295|Thermoanaerobacterales	186801|Clostridia	V	FemAB family	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158535_k127_3147163_7	383372.Rcas_1415	2.655e-33	149.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi,375A7@32061|Chloroflexia	32061|Chloroflexia	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR25158535_k127_3147163_0	643648.Slip_0944	3.011e-205	663.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,42JR0@68298|Syntrophomonadaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158535_k127_3147163_3	316274.Haur_4821	5.223e-92	314.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi	200795|Chloroflexi	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158535_k127_3147163_1	383372.Rcas_2157	2.019e-133	434.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,3766S@32061|Chloroflexia	32061|Chloroflexia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158535_k127_3147163_9	395494.Galf_2736	5.001e-19	103.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,44VV2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
SRR25158535_k127_3147163_11	192952.MM_3178	9.311e-10	72.0	arCOG02552@1|root,arCOG02552@2157|Archaea	2157|Archaea	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_5,Big_5,CHB_HEX_C_1,DUF11,NosD,PKD,PMBR
SRR25158535_k127_3147163_4	1120960.ATXG01000017_gene1391	2.733e-88	326.0	COG2133@1|root,COG2247@1|root,COG2133@2|Bacteria,COG2247@2|Bacteria,2IG1A@201174|Actinobacteria	201174|Actinobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GSDH
SRR25158535_k127_3147163_10	1169161.KB897734_gene427	5.825e-11	64.0	29YPV@1|root,30KJG@2|Bacteria,2GZ93@201174|Actinobacteria	201174|Actinobacteria	S	Superinfection immunity protein	-	-	-	-	-	-	-	-	-	-	-	-	Imm_superinfect
SRR25158535_k127_3152320_12	525904.Tter_0790	3.068e-86	293.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712,ko:K07714	ko02020,map02020	M00497,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158535_k127_3152320_36	314315.LCA_0421	2.432e-05	55.0	COG0789@1|root,COG0789@2|Bacteria,1VZ9X@1239|Firmicutes,4HYI3@91061|Bacilli,3FBR0@33958|Lactobacillaceae	91061|Bacilli	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158535_k127_3152320_6	1128421.JAGA01000003_gene3528	7.655e-111	374.0	COG0771@1|root,COG0771@2|Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_3152320_15	479434.Sthe_0146	4.405e-80	280.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi,27XXH@189775|Thermomicrobia	189775|Thermomicrobia	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158535_k127_3152320_31	1209984.BN978_06520	2.294e-12	75.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,238WR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_3152320_37	1121422.AUMW01000024_gene247	7.33e-05	53.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,262QH@186807|Peptococcaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_3152320_7	644966.Tmar_1208	9.419e-111	370.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3WCV2@538999|Clostridiales incertae sedis	186801|Clostridia	U	PFAM Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158535_k127_3152320_33	1380393.JHVP01000003_gene1140	8.028e-11	75.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria	201174|Actinobacteria	NU	Type ii secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158535_k127_3152320_20	1313172.YM304_18940	1.115e-55	207.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_3152320_17	1121468.AUBR01000003_gene631	4.23e-64	239.0	COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,24IAX@186801|Clostridia,42GB4@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158535_k127_3152320_27	649638.Trad_1788	5.389e-20	94.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158535_k127_3152320_35	867845.KI911784_gene1555	3.812e-06	51.0	COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia	32061|Chloroflexia	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158535_k127_3152320_32	429009.Adeg_1036	2.552e-11	70.0	COG1989@1|root,COG1989@2|Bacteria,1VFC1@1239|Firmicutes,25HJS@186801|Clostridia,42HFK@68295|Thermoanaerobacterales	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
SRR25158535_k127_3152320_4	357808.RoseRS_1273	6.301e-114	381.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158535_k127_3152320_2	479434.Sthe_0519	5.385e-179	572.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158535_k127_3152320_16	357808.RoseRS_1275	2.668e-68	243.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,3755T@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158535_k127_3152320_18	635013.TherJR_2807	8.189e-58	214.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,24GQ4@186801|Clostridia,261D6@186807|Peptococcaceae	186801|Clostridia	NU	PFAM type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158535_k127_3152320_29	398512.JQKC01000005_gene5358	9.377e-18	91.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,3WQGZ@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158535_k127_3152320_24	479434.Sthe_0523	2.174e-33	136.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,27YJE@189775|Thermomicrobia	189775|Thermomicrobia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158535_k127_3152320_26	1144275.COCOR_01642	1.766e-24	119.0	2BVHD@1|root,32QVZ@2|Bacteria,1N6CE@1224|Proteobacteria,430V5@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3152320_22	555088.DealDRAFT_1141	5.388e-43	178.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3152320_34	861299.J421_2592	2.338e-08	67.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.97	ko:K04477,ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158535_k127_3152320_11	765420.OSCT_0121	1.917e-95	322.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,374VA@32061|Chloroflexia	32061|Chloroflexia	EF	TIGRFAM ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158535_k127_3152320_1	42256.RradSPS_1561	7.12e-249	794.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CPGC@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158535_k127_3152320_21	309801.trd_A0787	3.988e-43	168.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158535_k127_3152320_23	1229172.JQFA01000002_gene2457	1.092e-33	143.0	COG0682@1|root,COG0682@2|Bacteria,1G0H2@1117|Cyanobacteria,1H96F@1150|Oscillatoriales	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158535_k127_3152320_5	1382356.JQMP01000004_gene638	3.565e-111	370.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,27XS7@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158535_k127_3152320_25	479434.Sthe_3392	1.403e-31	140.0	COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,27YFM@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
SRR25158535_k127_3152320_28	525904.Tter_0610	4.161e-19	102.0	COG3301@1|root,COG3301@2|Bacteria,2NQZC@2323|unclassified Bacteria	2|Bacteria	P	Polysulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158535_k127_3152320_14	479434.Sthe_3389	1.894e-83	312.0	COG0437@1|root,COG0437@2|Bacteria,2G9ZX@200795|Chloroflexi,27Y09@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3
SRR25158535_k127_3152320_0	1128421.JAGA01000002_gene1536	5e-324	1015.0	COG0243@1|root,COG0243@2|Bacteria,2NQFR@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158535_k127_3152320_19	1382356.JQMP01000001_gene1250	1.093e-56	205.0	COG0243@1|root,COG0243@2|Bacteria,2G62W@200795|Chloroflexi,27Z11@189775|Thermomicrobia	189775|Thermomicrobia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR25158535_k127_3152320_3	867903.ThesuDRAFT_00371	4.685e-116	394.0	COG0617@1|root,COG2254@1|root,COG0617@2|Bacteria,COG2254@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WCIJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158535_k127_3152320_13	1184609.KILIM_005_00720	4.296e-84	299.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158535_k127_3152320_9	525904.Tter_0588	2.883e-98	346.0	COG0411@1|root,COG0411@2|Bacteria,2NNYG@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158535_k127_3152320_10	525904.Tter_0587	2.69e-97	344.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_3152320_8	1173027.Mic7113_0201	8.941e-106	351.0	COG0559@1|root,COG0559@2|Bacteria,1G3S0@1117|Cyanobacteria,1H9UM@1150|Oscillatoriales	1117|Cyanobacteria	E	transport system permease	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_3152320_30	1170562.Cal6303_5524	4.844e-16	79.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria	1117|Cyanobacteria	E	'ABC-type branched-chain amino acid transport	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
SRR25158535_k127_3166101_8	1168065.DOK_01029	1.547e-59	213.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1J4FM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0066	HMGL-like,LeuA_dimer
SRR25158535_k127_3166101_5	644966.Tmar_0092	5.712e-105	364.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158535_k127_3166101_1	351607.Acel_1591	1.153e-201	660.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4ERE0@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158535_k127_3166101_7	298655.KI912267_gene6739	4.477e-68	251.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4ERFW@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158535_k127_3166101_11	485913.Krac_12605	6.527e-32	139.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	yihN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
SRR25158535_k127_3166101_10	1386089.N865_02800	5.053e-55	197.0	28M3Q@1|root,2ZAHT@2|Bacteria,2GM5B@201174|Actinobacteria,4FK3K@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3166101_6	309801.trd_A0315	1.548e-86	296.0	COG0265@1|root,COG0265@2|Bacteria,2GBRP@200795|Chloroflexi,27Z1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_3166101_17	452863.Achl_1730	5.509e-05	55.0	COG5520@1|root,COG5520@2|Bacteria,2HPZN@201174|Actinobacteria	201174|Actinobacteria	M	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,Glyco_hydr_30_2,RicinB_lectin_2
SRR25158535_k127_3166101_4	525904.Tter_2612	4.038e-121	437.0	COG0477@1|root,COG2814@2|Bacteria,2NQSV@2323|unclassified Bacteria	2|Bacteria	P	Fungal trichothecene efflux pump (TRI12)	mdr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3166101_12	709986.Deima_0737	2.097e-19	100.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_3166101_15	645127.ckrop_0595	9.57e-11	67.0	COG1158@1|root,COG1158@2|Bacteria,2IKUK@201174|Actinobacteria,22QPE@1653|Corynebacteriaceae	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3166101_3	926560.KE387023_gene2460	3.947e-124	411.0	COG1028@1|root,COG1028@2|Bacteria,1WJNR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_3166101_16	477184.KYC_20649	2.618e-10	64.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,3T1SJ@506|Alcaligenaceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158535_k127_3166101_9	383372.Rcas_3573	1.915e-57	205.0	COG0526@1|root,COG0526@2|Bacteria,2G8YT@200795|Chloroflexi	200795|Chloroflexi	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
SRR25158535_k127_3166101_14	685727.REQ_08010	4.183e-12	69.0	COG3526@1|root,COG3526@2|Bacteria,2IRQ4@201174|Actinobacteria,4G24X@85025|Nocardiaceae	201174|Actinobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158535_k127_3166101_0	1172188.KB911821_gene2028	1.026e-295	942.0	COG1404@1|root,COG1404@2|Bacteria,2GKJR@201174|Actinobacteria,4FFMV@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S8
SRR25158535_k127_3166101_2	1000565.METUNv1_04052	1.685e-143	462.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158535_k127_3166101_13	530564.Psta_4193	2.569e-14	77.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
SRR25158535_k127_3171818_12	266117.Rxyl_3072	5.226e-08	67.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_3171818_13	666684.AfiDRAFT_0346	1.578e-05	52.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158535_k127_3171818_2	671143.DAMO_0980	1.389e-193	623.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158535_k127_3171818_3	671143.DAMO_0981	1.582e-182	595.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158535_k127_3171818_4	1128421.JAGA01000001_gene2435	4.167e-106	357.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRR25158535_k127_3171818_9	1172179.AUKV01000009_gene4532	1.061e-30	126.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158535_k127_3171818_7	1206733.BAGC01000040_gene1564	9.464e-41	161.0	COG3467@1|root,COG3467@2|Bacteria,2IKUR@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158535_k127_3171818_8	404589.Anae109_3328	3.672e-36	146.0	COG2823@1|root,COG2823@2|Bacteria,1PY9X@1224|Proteobacteria,42YAD@68525|delta/epsilon subdivisions,2WU1C@28221|Deltaproteobacteria,2Z27W@29|Myxococcales	28221|Deltaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158535_k127_3171818_6	765911.Thivi_0900	1.512e-94	318.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
SRR25158535_k127_3171818_1	1187851.A33M_4208	1.652e-206	669.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
SRR25158535_k127_3171818_0	1049564.TevJSym_bb00050	2.818e-207	672.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158535_k127_3171818_5	1049564.TevJSym_bb00040	9.694e-98	354.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158535_k127_3171818_10	580332.Slit_2486	1.098e-29	138.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,2W99Y@28216|Betaproteobacteria,44WKY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158535_k127_3171818_11	882083.SacmaDRAFT_2739	1.463e-13	83.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_3179126_11	1158182.KB905024_gene102	1.824e-36	145.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158535_k127_3179126_0	1121422.AUMW01000007_gene3156	2.282e-264	843.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,260BY@186807|Peptococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158535_k127_3179126_13	886293.Sinac_0723	1.944e-26	115.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158535_k127_3179126_15	477974.Daud_0455	7.92e-21	96.0	COG0789@1|root,COG0789@2|Bacteria,1UR6D@1239|Firmicutes,24W15@186801|Clostridia,26715@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158535_k127_3179126_9	35754.JNYJ01000008_gene3271	2.178e-44	169.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria,4DEAY@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158535_k127_3179126_18	749414.SBI_05543	1.394e-10	66.0	COG0477@1|root,COG2814@2|Bacteria,2IDPG@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_3179126_10	1382306.JNIM01000001_gene385	7.033e-44	175.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158535_k127_3179126_12	552811.Dehly_1508	1.392e-32	134.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,34DCB@301297|Dehalococcoidia	301297|Dehalococcoidia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158535_k127_3179126_14	255470.cbdbA34	9.015e-22	100.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,34DAT@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_3179126_2	383372.Rcas_0561	8.16e-165	542.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	32061|Chloroflexia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158535_k127_3179126_3	525904.Tter_2095	6.843e-108	369.0	COG0642@1|root,COG2205@2|Bacteria,2NQXV@2323|unclassified Bacteria	2|Bacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158535_k127_3179126_4	1137269.AZWL01000004_gene1953	2.655e-68	245.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_3179126_1	525904.Tter_0032	2.839e-184	602.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158535_k127_3179126_19	684949.ATTJ01000001_gene2418	1.823e-08	63.0	2DR9X@1|root,33AUW@2|Bacteria,1WJ2Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
SRR25158535_k127_3179126_6	1128421.JAGA01000002_gene480	1.606e-57	214.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158535_k127_3179126_17	313625.BL107_15155	1.798e-13	84.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1GYXA@1129|Synechococcus	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158535_k127_3179126_8	1123250.KB908408_gene2199	2.757e-46	184.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes	909932|Negativicutes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158535_k127_3179126_16	485913.Krac_8476	2.286e-14	83.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_3179126_5	868595.Desca_1765	1.095e-65	229.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158535_k127_3179126_7	264732.Moth_1696	2.729e-51	205.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,42FS4@68295|Thermoanaerobacterales	186801|Clostridia	D	Stage II sporulation D domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
SRR25158535_k127_3187441_6	1411123.JQNH01000001_gene1220	1.445e-90	305.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	MA20_15045	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
SRR25158535_k127_3187441_2	383372.Rcas_2243	2.932e-128	431.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_3187441_19	882083.SacmaDRAFT_1462	1.301e-11	76.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4E3EN@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158535_k127_3187441_8	562970.Btus_2586	2.17e-51	208.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,4HTP0@91061|Bacilli,279M4@186823|Alicyclobacillaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158535_k127_3187441_20	157783.LK03_02965	0.0001243	51.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1S4J7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_3187441_12	215803.DB30_6030	7.532e-29	120.0	COG3729@1|root,COG3729@2|Bacteria,1NEPC@1224|Proteobacteria,439SW@68525|delta/epsilon subdivisions,2X55X@28221|Deltaproteobacteria,2Z05T@29|Myxococcales	28221|Deltaproteobacteria	S	Small hydrophilic plant seed protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
SRR25158535_k127_3187441_17	469383.Cwoe_4684	4.905e-23	107.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158535_k127_3187441_5	1961.JOAK01000008_gene4045	1.101e-96	337.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158535_k127_3187441_4	330214.NIDE0602	1.239e-106	363.0	COG1007@1|root,COG1007@2|Bacteria,3J0FN@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158535_k127_3187441_1	1131269.AQVV01000018_gene1926	1.768e-129	456.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158535_k127_3187441_0	525904.Tter_1533	3.001e-189	615.0	COG1009@1|root,COG1009@2|Bacteria,2NNM8@2323|unclassified Bacteria	2|Bacteria	CP	NADH-quinone oxidoreductase chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158535_k127_3187441_14	237368.SCABRO_02000	2.85e-24	105.0	COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158535_k127_3187441_18	388467.A19Y_1912	1.847e-19	103.0	COG0839@1|root,COG0839@2|Bacteria,1G2WH@1117|Cyanobacteria,1H7HW@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH ubiquinone oxidoreductase subunit 6 (chain J)	ndhG	-	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
SRR25158535_k127_3187441_7	909663.KI867151_gene2977	3.568e-86	302.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2MQ5S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158535_k127_3187441_16	521096.Tpau_3170	4.229e-23	109.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158535_k127_3187441_13	1382306.JNIM01000001_gene449	1.055e-28	121.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158535_k127_3187441_10	747365.Thena_0469	1.503e-31	139.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia,42GK2@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
SRR25158535_k127_3187441_15	882.DVU_1407	1.509e-23	113.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria,2M93A@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158535_k127_3187441_3	1329516.JPST01000003_gene1089	3.305e-109	383.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,27AZV@186824|Thermoactinomycetaceae	91061|Bacilli	S	GTP1/OBG	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158535_k127_3187441_9	999423.HMPREF9161_00421	1.83e-42	163.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158535_k127_3187441_11	1160707.AJIK01000015_gene2201	1.327e-30	130.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,26FE0@186818|Planococcaceae	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158535_k127_3187441_21	243164.DET1552	0.0008703	43.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3194785_4	338963.Pcar_2564	1.401e-16	91.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,43C0C@68525|delta/epsilon subdivisions,2WKKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3194785_5	326427.Cagg_3353	2.921e-15	81.0	2AKD7@1|root,31B4D@2|Bacteria,2GBQM@200795|Chloroflexi,3762Y@32061|Chloroflexia	32061|Chloroflexia	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158535_k127_3194785_1	1379698.RBG1_1C00001G0892	2.08e-109	364.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
SRR25158535_k127_3194785_2	1379698.RBG1_1C00001G0904	3.095e-43	179.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_3194785_3	1128421.JAGA01000003_gene2823	2.346e-35	145.0	COG2606@1|root,COG2606@2|Bacteria,2NPZ1@2323|unclassified Bacteria	2|Bacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158535_k127_3194785_0	1183438.GKIL_1801	2.03e-240	759.0	COG1048@1|root,COG1048@2|Bacteria,1G4YR@1117|Cyanobacteria	1117|Cyanobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158535_k127_3200536_2	485913.Krac_3228	3.735e-76	263.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi	200795|Chloroflexi	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_3200536_0	1382306.JNIM01000001_gene3174	5.347e-113	386.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_3200536_3	469383.Cwoe_3528	2.795e-52	204.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158535_k127_3200536_10	1007103.AFHW01000008_gene6212	0.0002845	49.0	29J6J@1|root,3063Z@2|Bacteria,1TZ59@1239|Firmicutes,4I8CC@91061|Bacilli,26ZJQ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3200536_1	1169154.KB897784_gene4129	2.38e-82	288.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158535_k127_3200536_4	1463921.JODF01000019_gene1321	4.904e-50	196.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_3200536_6	330084.JNYZ01000051_gene8947	7.768e-26	112.0	2EHMA@1|root,33BD2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158535_k127_3200536_9	337191.KTR9_3123	2.493e-06	59.0	COG1309@1|root,COG1309@2|Bacteria,2GN2F@201174|Actinobacteria,4GCB5@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3200536_7	1463841.JOIR01000045_gene1994	6.321e-09	63.0	COG1020@1|root,COG1020@2|Bacteria,2H4I2@201174|Actinobacteria	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_3200536_5	1121946.AUAX01000003_gene1482	2.054e-41	164.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4DDQZ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3203822_4	477974.Daud_0642	5.635e-63	238.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_3203822_0	1379698.RBG1_1C00001G0907	3.147e-118	407.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_3203822_5	477974.Daud_0885	1.033e-58	213.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,261IU@186807|Peptococcaceae	186801|Clostridia	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158535_k127_3203822_3	398767.Glov_2399	1.631e-66	257.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158535_k127_3203822_1	1187851.A33M_3197	6.311e-83	308.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRR25158535_k127_3203822_2	1187851.A33M_3196	1.834e-71	268.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRR25158535_k127_3203822_8	909663.KI867150_gene1782	2.012e-06	55.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria,43B9P@68525|delta/epsilon subdivisions,2X6NT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_3203822_6	404589.Anae109_0880	3.071e-17	94.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,42S32@68525|delta/epsilon subdivisions,2X5XE@28221|Deltaproteobacteria,2YTZ6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_3203822_7	717605.Theco_0141	1.6e-10	64.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,26RDT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
SRR25158535_k127_3234222_7	760568.Desku_1250	1.834e-57	207.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158535_k127_3234222_12	485913.Krac_0851	3.816e-48	189.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_3234222_17	1121346.KB899808_gene3413	6.948e-26	123.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,26R6Z@186822|Paenibacillaceae	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158535_k127_3234222_24	525904.Tter_1648	2.5e-21	100.0	COG0711@1|root,COG0711@2|Bacteria,2NRS9@2323|unclassified Bacteria	2|Bacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3234222_20	1382306.JNIM01000001_gene3739	4.934e-23	110.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158535_k127_3234222_26	485913.Krac_8243	5.958e-14	74.0	COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158535_k127_3234222_4	1122917.KB899659_gene5318	4.183e-85	292.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,26QJN@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158535_k127_3234222_21	1382356.JQMP01000003_gene1311	2.165e-22	108.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,27YFI@189775|Thermomicrobia	189775|Thermomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158535_k127_3234222_16	1382306.JNIM01000001_gene3743	1.58e-27	113.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158535_k127_3234222_15	292459.STH1453	3.845e-33	139.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158535_k127_3234222_1	867903.ThesuDRAFT_00301	2.898e-100	372.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WCRB@538999|Clostridiales incertae sedis	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158535_k127_3234222_5	1163409.UUA_02931	1.21e-79	277.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1X52Y@135614|Xanthomonadales	135614|Xanthomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158535_k127_3234222_13	469371.Tbis_1147	4.022e-48	191.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4E2VV@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158535_k127_3234222_0	1121423.JONT01000009_gene1465	4.459e-144	469.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158535_k127_3234222_18	857293.CAAU_0186	7.071e-24	104.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,36KP2@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158535_k127_3234222_25	1410609.JHVB01000004_gene495	1.256e-15	82.0	COG1837@1|root,COG1837@2|Bacteria,2J92T@203691|Spirochaetes	203691|Spirochaetes	S	Belongs to the UPF0109 family	yhbY	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158535_k127_3234222_19	1120950.KB892769_gene5391	9.329e-24	110.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4DRAZ@85009|Propionibacteriales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158535_k127_3234222_3	1382306.JNIM01000001_gene4081	1.569e-85	293.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158535_k127_3234222_27	370438.PTH_1646	5.186e-06	60.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes,249A4@186801|Clostridia,260ZB@186807|Peptococcaceae	186801|Clostridia	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158535_k127_3234222_14	760568.Desku_2140	3.252e-41	154.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158535_k127_3234222_6	1411123.JQNH01000001_gene3830	7.869e-60	219.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2TZ7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158535_k127_3234222_11	395961.Cyan7425_1166	4.888e-55	200.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,3KHNX@43988|Cyanothece	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158535_k127_3234222_9	926560.KE387023_gene2230	1.491e-56	218.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_3234222_8	926560.KE387023_gene2230	1.36e-56	220.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_3234222_2	1120960.ATXG01000017_gene1391	2.23e-89	318.0	COG2133@1|root,COG2247@1|root,COG2133@2|Bacteria,COG2247@2|Bacteria,2IG1A@201174|Actinobacteria	201174|Actinobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GSDH
SRR25158535_k127_3234222_10	1122182.KB903837_gene3780	7.863e-56	214.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_3234222_23	290397.Adeh_1910	7.092e-22	100.0	COG0792@1|root,COG0792@2|Bacteria,1Q8YJ@1224|Proteobacteria,43AAG@68525|delta/epsilon subdivisions,2X233@28221|Deltaproteobacteria,2Z2KT@29|Myxococcales	28221|Deltaproteobacteria	J	nuclease activity	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158535_k127_3234222_22	68219.JNXI01000032_gene7047	4.876e-22	109.0	28JQV@1|root,2Z7R2@2|Bacteria,2IBX7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3234222_28	105425.BBPL01000022_gene950	0.0004277	49.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria,2NF5B@228398|Streptacidiphilus	201174|Actinobacteria	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158535_k127_3239004_6	697281.Mahau_1481	4.247e-25	122.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158535_k127_3239004_5	1283299.AUKG01000003_gene450	4.742e-49	186.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158535_k127_3239004_8	326427.Cagg_2678	1.412e-10	74.0	COG2199@1|root,COG3706@2|Bacteria,2GBJP@200795|Chloroflexi,37810@32061|Chloroflexia	32061|Chloroflexia	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158535_k127_3239004_0	525904.Tter_0973	1.064e-142	464.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	ugpC	-	-	ko:K10112,ko:K10195	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00202,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	iJN678.ggtA	ABC_tran,TOBE,TOBE_2
SRR25158535_k127_3239004_1	479434.Sthe_3519	2.64e-131	427.0	COG0473@1|root,COG0473@2|Bacteria,2G8A7@200795|Chloroflexi,27XIB@189775|Thermomicrobia	189775|Thermomicrobia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
SRR25158535_k127_3239004_4	1111479.AXAR01000002_gene1865	1.294e-51	207.0	COG0006@1|root,COG0006@2|Bacteria,1UEEE@1239|Firmicutes,4HECJ@91061|Bacilli	91061|Bacilli	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158535_k127_3239004_7	682795.AciX8_4614	1.906e-13	80.0	COG2318@1|root,COG2318@2|Bacteria,3Y4TA@57723|Acidobacteria,2JP4M@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158535_k127_3239004_2	926554.KI912619_gene932	6.138e-89	312.0	COG0153@1|root,COG0153@2|Bacteria,1WIIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158535_k127_3239004_3	290397.Adeh_3469	2.389e-73	258.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_3278838_1	298655.KI912266_gene5174	8.503e-16	87.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4ES7K@85013|Frankiales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158535_k127_3278838_2	479434.Sthe_2046	4.849e-05	48.0	29U2R@1|root,30FC1@2|Bacteria,2G9M3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3278838_0	882083.SacmaDRAFT_0798	4.223e-141	484.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_3327031_11	324602.Caur_1303	3.559e-41	166.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi,3752U@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158535_k127_3327031_3	309801.trd_1669	1.49e-61	234.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_3327031_10	429009.Adeg_1033	1.637e-42	168.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,42EWT@68295|Thermoanaerobacterales	186801|Clostridia	T	Signal transduction histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158535_k127_3327031_19	935548.KI912159_gene4345	0.0009817	51.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,43PKT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158535_k127_3327031_12	926569.ANT_26880	6.381e-39	168.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3327031_13	1123288.SOV_5c00600	1.544e-37	160.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158535_k127_3327031_2	309801.trd_A0819	1.941e-75	273.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi,27XEV@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_3327031_5	1121472.AQWN01000008_gene2015	3.817e-50	195.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,261IN@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR25158535_k127_3327031_1	867845.KI911784_gene2607	1.334e-134	437.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,374UP@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_3327031_7	1227497.C491_13292	2.726e-46	191.0	COG3639@1|root,arCOG00173@2157|Archaea	2157|Archaea	P	COG3639 ABC-type phosphate phosphonate transport system, permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158535_k127_3327031_8	1229909.NSED_04900	2.77e-45	173.0	COG3638@1|root,arCOG00206@2157|Archaea,41SY4@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC transporter	-	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
SRR25158535_k127_3327031_4	698757.Pogu_2215	6.186e-60	219.0	COG3221@1|root,arCOG01805@2157|Archaea	2157|Archaea	P	ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158535_k127_3327031_6	1382306.JNIM01000001_gene2643	2.021e-47	178.0	COG1321@1|root,COG1321@2|Bacteria,2G7DY@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158535_k127_3327031_18	926569.ANT_27110	8.698e-06	57.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3327031_15	479432.Sros_3733	6.313e-19	94.0	COG1051@1|root,COG1051@2|Bacteria,2IIJJ@201174|Actinobacteria,4EJRA@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_3327031_16	1336235.JAEG01000012_gene4101	1.239e-13	83.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,4BDNX@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	MA20_34510	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
SRR25158535_k127_3327031_14	316274.Haur_4073	1.22e-23	117.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,375QG@32061|Chloroflexia	32061|Chloroflexia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158535_k127_3327031_0	525904.Tter_0063	1.232e-220	701.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158535_k127_3327031_9	309801.trd_1229	6.339e-44	164.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi,27XXK@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158535_k127_3329024_17	555079.Toce_0417	6.996e-06	57.0	arCOG04954@1|root,2Z95Q@2|Bacteria,1VUJT@1239|Firmicutes,250E9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3329024_10	66373.JOFQ01000014_gene2551	4.277e-42	167.0	COG2267@1|root,COG2267@2|Bacteria,2IH32@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_3329024_0	714943.Mucpa_0956	5.624e-278	877.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158535_k127_3329024_5	1120973.AQXL01000131_gene2036	1.109e-122	408.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,2788A@186823|Alicyclobacillaceae	91061|Bacilli	C	Transketolase, pyrimidine binding domain	dxpS	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158535_k127_3329024_7	479434.Sthe_3475	1.251e-97	334.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158535_k127_3329024_6	1382306.JNIM01000001_gene701	6.205e-114	377.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158535_k127_3329024_9	234267.Acid_0913	3.441e-46	187.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SRR25158535_k127_3329024_3	1408473.JHXO01000007_gene902	1.069e-169	547.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
SRR25158535_k127_3329024_12	929712.KI912613_gene1917	6.991e-29	119.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158535_k127_3329024_15	1382306.JNIM01000001_gene2847	3.601e-22	99.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158535_k127_3329024_11	525904.Tter_0600	5.625e-34	136.0	COG1146@1|root,COG1146@2|Bacteria,2NPWS@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7
SRR25158535_k127_3329024_14	1382356.JQMP01000004_gene533	2.57e-27	121.0	COG1547@1|root,COG1547@2|Bacteria,2GAFU@200795|Chloroflexi,27YQW@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158535_k127_3329024_16	986075.CathTA2_1460	2.049e-08	64.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli	91061|Bacilli	O	Nitrogen fixation protein NifU	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
SRR25158535_k127_3329024_1	479434.Sthe_3486	1.349e-200	647.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3329024_2	1382306.JNIM01000001_gene1826	2.139e-195	633.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
SRR25158535_k127_3329024_8	479434.Sthe_3484	1.248e-48	184.0	COG0630@1|root,COG0630@2|Bacteria,2G943@200795|Chloroflexi,27YBM@189775|Thermomicrobia	189775|Thermomicrobia	NU	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3329024_4	234267.Acid_7160	5.482e-128	427.0	COG0154@1|root,COG0154@2|Bacteria,3Y6WA@57723|Acidobacteria	57723|Acidobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158535_k127_3329024_13	1298864.AUEQ01000002_gene5939	1.85e-27	119.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,236CB@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_3346059_0	309801.trd_A0621	1.477e-144	475.0	COG0477@1|root,COG2814@2|Bacteria,2G8FT@200795|Chloroflexi,27Z09@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
SRR25158535_k127_3346059_1	309801.trd_0366	1.515e-126	412.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158535_k127_3356482_4	1238186.AOCN01000022_gene2480	4.24e-10	70.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4FM3R@85023|Microbacteriaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_3356482_1	479434.Sthe_2989	3.456e-80	287.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_3356482_0	1254432.SCE1572_19610	3.188e-80	275.0	COG3910@1|root,COG3910@2|Bacteria,1MZSY@1224|Proteobacteria,42R25@68525|delta/epsilon subdivisions,2WN2C@28221|Deltaproteobacteria,2YX77@29|Myxococcales	28221|Deltaproteobacteria	S	P-loop containing region of AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
SRR25158535_k127_3356482_5	867903.ThesuDRAFT_00033	1.608e-05	50.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
SRR25158535_k127_3356482_2	1173023.KE650771_gene5511	4.253e-47	177.0	COG0662@1|root,COG0662@2|Bacteria,1GFZG@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_3356482_7	264732.Moth_0807	0.0001137	51.0	COG4803@1|root,COG4803@2|Bacteria,1UJ40@1239|Firmicutes,24JIS@186801|Clostridia,42GJY@68295|Thermoanaerobacterales	186801|Clostridia	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269,YflT
SRR25158535_k127_3356482_3	697281.Mahau_0274	1.47e-33	134.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GY9@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158535_k127_3356482_6	1429046.RR21198_1278	8.374e-05	51.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4FUSK@85025|Nocardiaceae	201174|Actinobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
SRR25158535_k127_3415169_1	1382304.JNIL01000001_gene3479	2.02e-130	441.0	COG2355@1|root,COG2355@2|Bacteria,1TRNQ@1239|Firmicutes,4HEBU@91061|Bacilli	91061|Bacilli	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158535_k127_3415169_0	479434.Sthe_2668	0.0	1358.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158535_k127_3433974_2	234267.Acid_5922	1.54e-124	405.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_3433974_3	568706.BN118_3310	1.568e-107	389.0	COG1011@1|root,COG1011@2|Bacteria,1NCRU@1224|Proteobacteria,2VKXE@28216|Betaproteobacteria,3T5P7@506|Alcaligenaceae	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158535_k127_3433974_7	479434.Sthe_3125	1.592e-46	183.0	COG0477@1|root,COG2814@2|Bacteria,2G6HS@200795|Chloroflexi,27XYB@189775|Thermomicrobia	189775|Thermomicrobia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3433974_0	479434.Sthe_1030	0.0	1528.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158535_k127_3433974_1	1394178.AWOO02000003_gene2772	0.0	1356.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4EFYQ@85012|Streptosporangiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158535_k127_3433974_5	1120973.AQXL01000125_gene3126	1.858e-67	249.0	COG5267@1|root,COG5267@2|Bacteria,1VGX0@1239|Firmicutes,4HUYI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158535_k127_3433974_4	1382306.JNIM01000001_gene706	1.347e-77	275.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158535_k127_3433974_8	263358.VAB18032_20680	2.208e-42	178.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria,4DDH1@85008|Micromonosporales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158535_k127_3433974_11	318424.EU78_09360	4.385e-16	91.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,238X2@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ferric reductase like transmembrane component	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158535_k127_3433974_10	1540221.JQNI01000004_gene405	3.526e-20	103.0	COG0477@1|root,COG2814@2|Bacteria,1WMVG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_3433974_6	292564.Cyagr_0976	2.382e-58	214.0	COG0741@1|root,COG0741@2|Bacteria,1GMX8@1117|Cyanobacteria,22SGU@167375|Cyanobium	1117|Cyanobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158535_k127_3433974_12	378806.STAUR_6543	3.404e-05	57.0	COG0308@1|root,COG0308@2|Bacteria,1QT4M@1224|Proteobacteria,43EVK@68525|delta/epsilon subdivisions,2X215@28221|Deltaproteobacteria,2YY8D@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158535_k127_3433974_9	398525.KB900701_gene5785	1.095e-26	118.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,3JW0V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
SRR25158535_k127_3498133_1	479434.Sthe_0805	1.851e-218	689.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,27Y57@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158535_k127_3498133_3	500153.JOEK01000016_gene3419	3.611e-143	478.0	COG1649@1|root,COG1649@2|Bacteria,2GKNP@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,GHL10
SRR25158535_k127_3498133_9	1333856.L686_14915	5.115e-14	79.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1YZRB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
SRR25158535_k127_3498133_2	1122939.ATUD01000012_gene3193	3.905e-172	568.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4CP77@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_3498133_4	65497.JODV01000008_gene132	9.194e-138	460.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4E0HP@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_3498133_8	405948.SACE_4444	5.414e-21	96.0	COG3339@1|root,COG3339@2|Bacteria,2IMW8@201174|Actinobacteria,4E3PY@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158535_k127_3498133_6	1122611.KB903974_gene2885	1.231e-64	231.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158535_k127_3498133_7	1380393.JHVP01000001_gene2240	1.117e-35	149.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4ESAR@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD, ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_3498133_0	1521187.JPIM01000114_gene1936	1.014e-222	702.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,376WB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158535_k127_3498133_5	311424.DhcVS_1190	1.405e-69	244.0	COG0176@1|root,COG0176@2|Bacteria,2G6T8@200795|Chloroflexi,34D7M@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158535_k127_3498133_10	292459.STH475	1.748e-12	75.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158535_k127_359102_8	379066.GAU_2857	9.306e-120	399.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_359102_6	1278073.MYSTI_05936	8.685e-142	492.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158535_k127_359102_19	1121468.AUBR01000034_gene1361	7.653e-66	258.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42HX8@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248,ko:K18244	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_359102_38	1048339.KB913029_gene3527	2.927e-08	64.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ERYG@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158535_k127_359102_35	589865.DaAHT2_1939	6.515e-14	80.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MK90@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158535_k127_359102_17	1120972.AUMH01000008_gene2054	7.563e-73	267.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli	91061|Bacilli	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	amaB	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158535_k127_359102_30	37919.EP51_17380	7.493e-30	136.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4G8U5@85025|Nocardiaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158535_k127_359102_27	1125863.JAFN01000001_gene169	9.653e-43	160.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcription regulator MerR DNA binding	-	-	-	ko:K21902	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158535_k127_359102_9	1385515.N791_03100	2.51e-119	404.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1X3A8@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_359102_16	926554.KI912636_gene3149	5.755e-84	304.0	COG1250@1|root,COG1250@2|Bacteria,1WIN8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158535_k127_359102_7	502025.Hoch_3778	2.043e-129	430.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_359102_3	562970.Btus_3278	2.466e-159	535.0	COG0247@1|root,COG0479@1|root,COG2181@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,277YN@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158535_k127_359102_22	644282.Deba_2883	2.435e-55	202.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158535_k127_359102_20	880073.Calab_1576	1.772e-64	236.0	COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158535_k127_359102_15	479434.Sthe_1203	2.216e-89	308.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,27YYB@189775|Thermomicrobia	189775|Thermomicrobia	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_359102_1	869210.Marky_1004	3.443e-213	677.0	COG1884@1|root,COG1884@2|Bacteria,1WIX7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158535_k127_359102_41	1382356.JQMP01000004_gene221	3.851e-05	56.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
SRR25158535_k127_359102_23	485918.Cpin_0241	3.502e-49	192.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes	976|Bacteroidetes	I	TIGRFAM methylmalonyl-CoA mutase C-terminal domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158535_k127_359102_12	1349767.GJA_42	5.042e-103	352.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,473VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_359102_10	1192868.CAIU01000015_gene1977	1.613e-113	393.0	COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,2TW2E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158535_k127_359102_21	365046.Rta_30220	1.426e-55	215.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2WEY6@28216|Betaproteobacteria,4AIME@80864|Comamonadaceae	1224|Proteobacteria	L	Beta-lactamase superfamily domain	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158535_k127_359102_25	1380393.JHVP01000004_gene323	1.559e-44	182.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria,4EW4Z@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158535_k127_359102_37	224325.AF_1672	4.579e-10	68.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SRR25158535_k127_359102_0	379066.GAU_1783	5.609e-226	720.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158535_k127_359102_4	861299.J421_3417	6.767e-149	490.0	COG0439@1|root,COG0439@2|Bacteria,1ZTBD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158535_k127_359102_39	590998.Celf_2558	8.741e-08	65.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4F1W1@85016|Cellulomonadaceae	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158535_k127_359102_5	357808.RoseRS_1297	2.181e-143	494.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158535_k127_359102_2	292459.STH1186	1.417e-196	636.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia	186801|Clostridia	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158535_k127_359102_32	1111479.AXAR01000003_gene1714	2.018e-23	117.0	COG0346@1|root,COG2185@1|root,COG0346@2|Bacteria,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4IRRS@91061|Bacilli,2794J@186823|Alicyclobacillaceae	91061|Bacilli	EI	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,Glyoxalase_4
SRR25158535_k127_359102_28	643648.Slip_1781	1.123e-36	153.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,42JX6@68298|Syntrophomonadaceae	186801|Clostridia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158535_k127_359102_40	1303518.CCALI_01483	6.671e-07	63.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.5	ko:K00848,ko:K00851,ko:K00854	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
SRR25158535_k127_359102_34	1123242.JH636435_gene2228	1.235e-16	94.0	28II6@1|root,2Z8JB@2|Bacteria,2IXG8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_359102_29	479434.Sthe_0912	2.71e-33	136.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,27YBZ@189775|Thermomicrobia	189775|Thermomicrobia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158535_k127_359102_33	1410622.JNKY01000015_gene275	9.214e-18	92.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,27IG5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158535_k127_359102_24	1117108.PAALTS15_10204	3.962e-47	175.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,26RAQ@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158535_k127_359102_13	309801.trd_0177	2.882e-97	337.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158535_k127_359102_18	246194.CHY_1513	5.318e-69	245.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,42FRF@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158535_k127_359102_31	1151119.KB895493_gene1493	1.588e-27	120.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,1W91C@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_359102_14	660470.Theba_2214	1.054e-95	331.0	COG0404@1|root,COG0404@2|Bacteria,2GC8B@200918|Thermotogae	200918|Thermotogae	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2007,GCV_T,GCV_T_C
SRR25158535_k127_359102_26	1120972.AUMH01000010_gene366	5.369e-43	161.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,279UB@186823|Alicyclobacillaceae	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158535_k127_359102_11	383372.Rcas_2283	3.9e-106	359.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi,376C6@32061|Chloroflexia	32061|Chloroflexia	C	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158535_k127_359102_36	1151117.AJLF01000001_gene1051	5.39e-13	82.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158535_k127_40286_4	1449347.JQLN01000007_gene1264	5.473e-36	147.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,2M3T6@2063|Kitasatospora	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_40286_1	994479.GL877879_gene5008	2.211e-96	346.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4E8JN@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158535_k127_40286_3	357808.RoseRS_2012	8.341e-64	234.0	28HAQ@1|root,2Z7N0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR25158535_k127_40286_0	986075.CathTA2_0959	6.51e-321	1002.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_40286_2	1128421.JAGA01000002_gene455	1.169e-87	307.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158535_k127_40286_8	1380347.JNII01000009_gene2271	4.936e-23	113.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EVFA@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_40286_7	555088.DealDRAFT_2617	2.484e-23	108.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,42K2Y@68298|Syntrophomonadaceae	186801|Clostridia	K	Sigma-70 region 3	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158535_k127_40286_5	498761.HM1_3129	2.92e-33	130.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_40286_9	882086.SacxiDRAFT_3425	1.036e-17	91.0	COG0468@1|root,COG1372@1|root,COG0468@2|Bacteria,COG1372@2|Bacteria,2GJ4P@201174|Actinobacteria,4DZ5K@85010|Pseudonocardiales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_40286_11	558169.AGAV01000024_gene31	4.449e-10	60.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_40286_6	496833.MBIO_0803	1.45e-24	105.0	2B9ZZ@1|root,323DM@2|Bacteria,3WUUY@544448|Tenericutes	544448|Tenericutes	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_40286_10	469615.FGAG_01614	9.899e-13	68.0	2B9ZZ@1|root,323DM@2|Bacteria,37CAK@32066|Fusobacteria	32066|Fusobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_445704_13	1511.CLOST_2198	1.193e-56	203.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25QSZ@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158535_k127_445704_21	1048339.KB913029_gene2751	1.041e-35	153.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4ES9Y@85013|Frankiales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158535_k127_445704_30	877411.JMMA01000002_gene2704	9.345e-21	105.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3WJVK@541000|Ruminococcaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158535_k127_445704_2	309801.trd_0981	5.188e-109	364.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi,27XVH@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158535_k127_445704_20	1123288.SOV_2c10000	2.377e-40	151.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4H4P6@909932|Negativicutes	909932|Negativicutes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158535_k127_445704_25	273068.TTE2287	5.569e-32	128.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,42GWK@68295|Thermoanaerobacterales	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158535_k127_445704_6	1246626.BleG1_0040	8.526e-73	258.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,1ZBA9@1386|Bacillus	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158535_k127_445704_11	1173024.KI912148_gene4004	2.122e-57	216.0	COG0197@1|root,COG0197@2|Bacteria,1G55B@1117|Cyanobacteria,1JIH0@1189|Stigonemataceae	1117|Cyanobacteria	J	Ribosomal protein L16p/L10e	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158535_k127_445704_35	1385935.N836_33670	4.655e-07	57.0	COG0255@1|root,COG0255@2|Bacteria,1GFDE@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L29
SRR25158535_k127_445704_32	401526.TcarDRAFT_1007	1.406e-16	87.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4H533@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158535_k127_445704_17	525904.Tter_0725	1.916e-44	173.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158535_k127_445704_27	246194.CHY_2298	1.577e-28	124.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158535_k127_445704_5	292459.STH3063	2.393e-73	257.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158535_k127_445704_31	357808.RoseRS_1172	6.397e-18	93.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi,375ZA@32061|Chloroflexia	32061|Chloroflexia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158535_k127_445704_19	1304284.L21TH_0906	1.437e-41	159.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158535_k127_445704_7	1121272.KB903250_gene2991	8.903e-67	234.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DAXG@85008|Micromonosporales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158535_k127_445704_23	1379270.AUXF01000004_gene3017	1.076e-32	131.0	COG0256@1|root,COG0256@2|Bacteria,1ZTUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158535_k127_445704_9	871968.DESME_01535	1.532e-61	222.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,261HV@186807|Peptococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158535_k127_445704_36	1121106.JQKB01000027_gene1893	1.21e-06	59.0	COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,2JTU5@204441|Rhodospirillales	204441|Rhodospirillales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158535_k127_445704_24	1131269.AQVV01000040_gene1632	4.568e-32	134.0	COG0200@1|root,COG0200@2|Bacteria	2|Bacteria	J	rRNA binding	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158535_k127_445704_0	1382356.JQMP01000003_gene2280	3.689e-137	456.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158535_k127_445704_18	1504319.GM45_2545	1.254e-43	181.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,3UWJJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_445704_4	867903.ThesuDRAFT_00580	3.665e-75	270.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WCH7@538999|Clostridiales incertae sedis	186801|Clostridia	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158535_k127_445704_26	1304284.L21TH_0916	1.539e-29	118.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,36KM7@31979|Clostridiaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158535_k127_445704_34	102129.Lepto7375DRAFT_3696	1.025e-11	65.0	COG0257@1|root,COG0257@2|Bacteria,1GAEI@1117|Cyanobacteria,1HDS8@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158535_k127_445704_16	1382306.JNIM01000001_gene3524	6.559e-50	181.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158535_k127_445704_14	867845.KI911784_gene914	4.068e-54	196.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,375IQ@32061|Chloroflexia	32061|Chloroflexia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158535_k127_445704_8	1089553.Tph_c25580	1.029e-63	229.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158535_k127_445704_3	1089553.Tph_c25570	8.764e-99	333.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,42FI6@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158535_k127_445704_29	335541.Swol_2303	1.454e-25	123.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,42K3C@68298|Syntrophomonadaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158535_k127_445704_15	555079.Toce_0152	3.534e-51	203.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158535_k127_445704_10	292459.STH3041	6.162e-58	204.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158535_k127_445704_22	1121335.Clst_0267	1.897e-34	142.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158535_k127_445704_12	1048834.TC41_3001	7.285e-57	209.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,2781N@186823|Alicyclobacillaceae	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158535_k127_445704_28	562970.Btus_0197	7.9e-27	124.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,278HJ@186823|Alicyclobacillaceae	91061|Bacilli	S	YbbR-like protein	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158535_k127_445704_1	349161.Dred_0294	2.192e-128	423.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,260XD@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_445704_33	1122611.KB903963_gene4638	6.329e-14	73.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EFWB@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRR25158535_k127_447051_4	662479.C440_17081	2.855e-07	60.0	arCOG02399@1|root,arCOG02399@2157|Archaea,2XVVI@28890|Euryarchaeota,23UYC@183963|Halobacteria	183963|Halobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158535_k127_447051_3	662479.C440_17076	1.631e-10	65.0	arCOG06181@1|root,arCOG06181@2157|Archaea,2Y06C@28890|Euryarchaeota,23XFD@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_447051_1	926560.KE387023_gene2241	3.142e-22	112.0	COG0454@1|root,COG0456@2|Bacteria,1WMM3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_447051_2	1294265.JCM21738_2818	1.044e-16	94.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158535_k127_447051_0	1128421.JAGA01000002_gene1189	1.078e-51	188.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_448607_8	1489678.RDMS_05855	4.907e-79	276.0	COG0119@1|root,COG0119@2|Bacteria,1WI4S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158535_k127_448607_3	525904.Tter_0188	6.099e-130	427.0	COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria	2|Bacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iHN637.CLJU_RS07505,iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iIT341.HP0330,iJN746.PP_4678,iLF82_1304.LF82_1103,iLJ478.TM0550	IlvC,IlvN
SRR25158535_k127_448607_2	525904.Tter_0186	9.181e-172	558.0	COG0028@1|root,COG0028@2|Bacteria,2NNMW@2323|unclassified Bacteria	2|Bacteria	EH	thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_448607_7	246196.MSMEI_2433	4.316e-81	293.0	COG1167@1|root,COG1167@2|Bacteria,2GNFG@201174|Actinobacteria,237ND@1762|Mycobacteriaceae	201174|Actinobacteria	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,GntR
SRR25158535_k127_448607_36	929712.KI912613_gene779	4.283e-12	75.0	COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K07494,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	GAF,HTH_30
SRR25158535_k127_448607_12	404589.Anae109_2572	7.678e-70	261.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158535_k127_448607_37	694440.JOMF01000005_gene288	5.813e-11	75.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR25158535_k127_448607_33	67315.JOBD01000003_gene5875	6.748e-15	76.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158535_k127_448607_24	309801.trd_A0609	1.06e-34	141.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158535_k127_448607_15	290397.Adeh_2091	3.68e-62	226.0	COG0266@1|root,COG0266@2|Bacteria,1N1J5@1224|Proteobacteria,433TA@68525|delta/epsilon subdivisions,2X3D6@28221|Deltaproteobacteria,2YVHV@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_448607_0	404589.Anae109_1724	0.0	1678.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158535_k127_448607_28	383372.Rcas_0729	8.94e-28	120.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi,375X7@32061|Chloroflexia	32061|Chloroflexia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158535_k127_448607_25	1054860.KB913030_gene5243	2.401e-32	131.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158535_k127_448607_21	219305.MCAG_00337	5.156e-48	183.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4DDWS@85008|Micromonosporales	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158535_k127_448607_34	1227495.C487_00860	2.254e-13	79.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XWJJ@28890|Euryarchaeota,23VFJ@183963|Halobacteria	183963|Halobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158535_k127_448607_20	1223523.H340_29084	1.653e-54	201.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158535_k127_448607_16	1206739.BAGJ01000027_gene1820	6.66e-58	214.0	COG3170@1|root,COG3170@2|Bacteria,2ICMF@201174|Actinobacteria,4G99M@85025|Nocardiaceae	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_448607_19	582402.Hbal_3211	4.559e-55	201.0	COG0500@1|root,COG2226@2|Bacteria,1RFDN@1224|Proteobacteria,2UEKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_448607_5	479434.Sthe_1728	7.944e-88	306.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,27Y1I@189775|Thermomicrobia	189775|Thermomicrobia	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158535_k127_448607_23	935839.JAGJ01000027_gene2799	3.212e-37	163.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria,4F3TC@85017|Promicromonosporaceae	201174|Actinobacteria	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
SRR25158535_k127_448607_9	526225.Gobs_0079	2.516e-77	288.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158535_k127_448607_26	113395.AXAI01000008_gene825	1.317e-29	128.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JQV4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,PAS_8,PAS_9
SRR25158535_k127_448607_30	573370.DMR_35140	1.068e-22	115.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MAVC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
SRR25158535_k127_448607_17	247490.KSU1_C0861	3.206e-56	219.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158535_k127_448607_6	1499967.BAYZ01000069_gene1845	1.838e-86	295.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_448607_4	1254432.SCE1572_38485	7.546e-117	384.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_448607_13	1382304.JNIL01000001_gene1097	2.251e-69	259.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli	91061|Bacilli	F	amidohydrolase	-	-	-	ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_448607_14	1157635.KB892035_gene6294	4.435e-67	244.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SLT
SRR25158535_k127_448607_38	1123242.JH636436_gene355	1.973e-05	54.0	COG2318@1|root,COG2318@2|Bacteria,2J0BN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158535_k127_448607_1	1122138.AQUZ01000019_gene8188	2.487e-197	632.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158535_k127_448607_31	298654.FraEuI1c_0431	1.398e-22	100.0	COG2261@1|root,COG2261@2|Bacteria,2GS37@201174|Actinobacteria,4ETMQ@85013|Frankiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158535_k127_448607_11	1380370.JIBA01000018_gene534	3.977e-70	241.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4FH86@85021|Intrasporangiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158535_k127_448607_32	388413.ALPR1_16284	5.146e-21	98.0	2E3HM@1|root,32YG7@2|Bacteria,4NW2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_448607_22	682795.AciX8_2177	3.569e-43	166.0	COG0596@1|root,COG0596@2|Bacteria,3Y5W5@57723|Acidobacteria,2JKEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_448607_39	443218.AS9A_2221	0.0002152	45.0	arCOG06277@1|root,330C9@2|Bacteria,2IJX3@201174|Actinobacteria,23994@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_448607_35	525368.HMPREF0591_0549	1.334e-12	74.0	arCOG06277@1|root,330C9@2|Bacteria,2IJX3@201174|Actinobacteria,23994@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_448607_10	754035.Mesau_00601	8.29e-76	256.0	COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria,2UAQG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_472184_21	393283.XP_007837262.1	1.075e-12	70.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi,3R1JE@4890|Ascomycota,215RQ@147550|Sordariomycetes	4751|Fungi	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158535_k127_472184_20	1313172.YM304_04440	2.759e-13	81.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158535_k127_472184_1	479434.Sthe_3011	2.33e-142	474.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_472184_25	485913.Krac_11890	2.049e-07	61.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_472184_13	1120949.KB903305_gene7054	6.599e-40	158.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria,4DCAY@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_472184_16	981383.AEWH01000063_gene1955	4.821e-25	117.0	COG0842@1|root,COG0842@2|Bacteria,1V0J8@1239|Firmicutes,4HEBH@91061|Bacilli	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_472184_4	1122138.AQUZ01000039_gene8021	3.631e-107	356.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4DNSV@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_472184_12	1278073.MYSTI_07208	2.455e-45	169.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158535_k127_472184_26	469383.Cwoe_2073	8.183e-07	57.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4CT5D@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158535_k127_472184_0	1382306.JNIM01000001_gene426	0.0	1076.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158535_k127_472184_10	1122138.AQUZ01000045_gene4445	6.688e-65	245.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2ID98@201174|Actinobacteria,4DQDB@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
SRR25158535_k127_472184_22	1146883.BLASA_3317	2.942e-12	76.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_472184_24	269799.Gmet_2970	9.908e-09	63.0	COG2227@1|root,COG2227@2|Bacteria,1QXN3@1224|Proteobacteria,43C46@68525|delta/epsilon subdivisions,2X7EM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_472184_17	935836.JAEL01000056_gene1276	5.902e-20	100.0	COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,4HIRR@91061|Bacilli,1ZGEH@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_472184_14	485913.Krac_2886	4.029e-30	133.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_472184_3	1121335.Clst_1330	2.182e-109	368.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3WG8N@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158535_k127_472184_5	479434.Sthe_0414	5.862e-96	348.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia	189775|Thermomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158535_k127_472184_2	1262915.BN574_00428	2.22e-124	417.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4H25A@909932|Negativicutes	909932|Negativicutes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158535_k127_472184_8	479434.Sthe_2722	2.725e-69	249.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_472184_7	187272.Mlg_2099	9.272e-87	295.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1WXFH@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158535_k127_472184_18	56110.Oscil6304_2169	8.654e-20	100.0	arCOG08099@1|root,33EDX@2|Bacteria,1GGAP@1117|Cyanobacteria	1117|Cyanobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_472184_23	1541960.KQ78_01975	2.896e-11	74.0	arCOG08099@1|root,33EDX@2|Bacteria	2|Bacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_472184_9	234267.Acid_0055	1.188e-67	237.0	2AY4N@1|root,31Q6J@2|Bacteria,3Y7H6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_472184_15	1341646.CBMO010000136_gene2661	9.961e-30	128.0	COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,232YT@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ion transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158535_k127_472184_6	1382306.JNIM01000001_gene536	6.72e-89	302.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158535_k127_552337_21	1382306.JNIM01000001_gene3998	8.751e-17	91.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158535_k127_552337_20	1047013.AQSP01000144_gene839	8.237e-18	98.0	COG1807@1|root,COG1807@2|Bacteria,2NRV3@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158535_k127_552337_18	926550.CLDAP_37690	1.06e-31	138.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158535_k127_552337_17	765420.OSCT_2350	1.6e-45	177.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158535_k127_552337_4	760568.Desku_0719	4.627e-108	363.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,26192@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
SRR25158535_k127_552337_13	1605.Lani381_0056	3.038e-56	210.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,3F4F8@33958|Lactobacillaceae	91061|Bacilli	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_552337_15	479434.Sthe_2755	1.674e-55	205.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158535_k127_552337_10	1229780.BN381_130322	8.164e-72	255.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRR25158535_k127_552337_12	1229780.BN381_130323	2.354e-56	214.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K16692,ko:K20998	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	CbiA,Wzz
SRR25158535_k127_552337_16	1229780.BN381_130324	3.279e-54	216.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158535_k127_552337_2	1229780.BN381_130325	9.709e-127	413.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	wcaA	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
SRR25158535_k127_552337_7	1229780.BN381_130326	1.086e-86	309.0	COG0823@1|root,COG3307@1|root,COG0823@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Wzy_C
SRR25158535_k127_552337_6	1229780.BN381_130326	3.647e-91	335.0	COG0823@1|root,COG3307@1|root,COG0823@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Wzy_C
SRR25158535_k127_552337_9	1229780.BN381_130327	4.645e-75	267.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158535_k127_552337_14	1229780.BN381_130328	4.366e-56	216.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MetW,Methyltransf_11,Methyltransf_20,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158535_k127_552337_5	1229780.BN381_130329	3.815e-101	341.0	COG1091@1|root,COG1091@2|Bacteria,2HG64@201174|Actinobacteria,3UXQ6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
SRR25158535_k127_552337_0	1229780.BN381_130330	1.927e-146	473.0	COG0463@1|root,COG0463@2|Bacteria,2GJ9C@201174|Actinobacteria	201174|Actinobacteria	M	Reversibly glycosylated polypeptide	-	-	-	-	-	-	-	-	-	-	-	-	RGP
SRR25158535_k127_552337_3	443143.GM18_3813	7.239e-117	392.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_552337_1	56107.Cylst_6224	6.421e-142	487.0	COG1020@1|root,COG1020@2|Bacteria,1GQ70@1117|Cyanobacteria,1HRJ2@1161|Nostocales	1117|Cyanobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158535_k127_552337_22	396588.Tgr7_2385	1.852e-09	71.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,1SJ0G@1236|Gammaproteobacteria,1X1K5@135613|Chromatiales	135613|Chromatiales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158535_k127_552337_19	1231241.Mc24_08164	2.669e-22	110.0	COG1045@1|root,COG1045@2|Bacteria,2GCY7@200918|Thermotogae	200918|Thermotogae	E	Serine acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
SRR25158535_k127_552337_11	1229780.BN381_130333	9.837e-59	227.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,3UXQ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_552337_8	1229780.BN381_130334	3.036e-84	305.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PD40
SRR25158535_k127_590586_0	479434.Sthe_0666	1.262e-155	507.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	2|Bacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_590586_2	479434.Sthe_0419	1.263e-63	240.0	COG0842@1|root,COG0842@2|Bacteria,2G8I5@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158535_k127_590586_1	1128421.JAGA01000002_gene314	2.322e-78	286.0	COG1131@1|root,COG1131@2|Bacteria,2NQPB@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_613821_13	234267.Acid_5657	3.905e-23	111.0	COG5349@1|root,COG5349@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF983)	MA20_36345	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158535_k127_613821_1	589865.DaAHT2_0143	5.201e-316	980.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158535_k127_613821_3	713587.THITH_11265	3.725e-271	891.0	COG3280@1|root,COG3280@2|Bacteria	2|Bacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
SRR25158535_k127_613821_4	240015.ACP_0843	3.036e-221	705.0	COG0366@1|root,COG0366@2|Bacteria,3Y2ZW@57723|Acidobacteria,2JICY@204432|Acidobacteriia	204432|Acidobacteriia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158535_k127_613821_0	1382356.JQMP01000004_gene486	0.0	1279.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158535_k127_613821_2	479434.Sthe_1091	6.159e-275	860.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158535_k127_613821_18	1110697.NCAST_05_02430	5.305e-06	53.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4FWFF@85025|Nocardiaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_613821_14	290397.Adeh_2635	1.376e-18	98.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z1WY@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_613821_11	1380394.JADL01000001_gene2780	8.112e-42	164.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2U1CS@28211|Alphaproteobacteria,2JWGP@204441|Rhodospirillales	204441|Rhodospirillales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRR25158535_k127_613821_12	1235797.C816_03459	2.631e-32	144.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,2N755@216572|Oscillospiraceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158535_k127_613821_9	370438.PTH_2894	3.17e-73	267.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,261ZB@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	kduD	-	1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76	ko:K00046,ko:K00065,ko:K18009	ko00040,ko00650,map00040,map00650	-	R01542,R03707,R09078,R10505	RC00089,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158535_k127_613821_6	1380390.JIAT01000009_gene549	1.096e-133	453.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CPER@84995|Rubrobacteria	84995|Rubrobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158535_k127_613821_17	1463825.JNXC01000021_gene7182	8.483e-13	74.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4DYFF@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_613821_10	675635.Psed_0410	1.717e-51	193.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158535_k127_613821_5	365046.Rta_31990	2.182e-136	441.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_613821_7	1123504.JQKD01000012_gene1341	1.033e-94	325.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_613821_8	1095769.CAHF01000011_gene2301	5.213e-75	274.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158535_k127_613821_16	1121378.KB899704_gene2482	1.313e-15	89.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_635514_0	44060.JODL01000044_gene4017	9.901e-226	727.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_635514_9	882086.SacxiDRAFT_2842	2.365e-08	59.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4E7TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158535_k127_635514_10	1394178.AWOO02000015_gene7096	3.122e-08	66.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_635514_6	106370.Francci3_4465	2.085e-20	98.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria,4ET1W@85013|Frankiales	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_635514_12	867903.ThesuDRAFT_01405	2.104e-06	50.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158535_k127_635514_7	867903.ThesuDRAFT_01405	4.458e-16	84.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158535_k127_635514_5	309801.trd_1817	5.674e-42	168.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_635514_4	1382356.JQMP01000003_gene1430	6.537e-52	196.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_635514_8	1206733.BAGC01000044_gene850	7.534e-12	77.0	COG1308@1|root,COG1308@2|Bacteria,2GVBU@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
SRR25158535_k127_635514_3	479434.Sthe_2605	6.884e-66	233.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia	189775|Thermomicrobia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158535_k127_635514_11	670307.HYPDE_29788	3.244e-07	56.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3N6G0@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158535_k127_635514_2	262316.MAP_2330c	1.017e-134	449.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,236VV@1762|Mycobacteriaceae	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_635514_1	926549.KI421517_gene2964	1.568e-201	648.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158535_k127_638845_2	593750.Metfor_0443	3.325e-123	406.0	COG0677@1|root,arCOG00252@2157|Archaea,2XUJT@28890|Euryarchaeota	28890|Euryarchaeota	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158535_k127_638845_3	593750.Metfor_0441	3.025e-122	415.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,2N9FX@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158535_k127_638845_9	593750.Metfor_0440	1.915e-71	262.0	COG0463@1|root,arCOG00895@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158535_k127_638845_4	593750.Metfor_0439	1.037e-100	355.0	COG0451@1|root,arCOG01369@2157|Archaea	2157|Archaea	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158535_k127_638845_1	1238182.C882_3335	1.642e-151	495.0	COG0380@1|root,COG0380@2|Bacteria,1R2XM@1224|Proteobacteria	1224|Proteobacteria	G	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_14
SRR25158535_k127_638845_13	429009.Adeg_0506	4.488e-45	188.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,42FH8@68295|Thermoanaerobacterales	186801|Clostridia	GM	PFAM ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR25158535_k127_638845_21	794903.OPIT5_14415	3.313e-11	76.0	COG0500@1|root,COG2226@2|Bacteria,46SQ9@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_638845_15	1229780.BN381_130135	1.165e-21	98.0	COG2002@1|root,COG2002@2|Bacteria,2GUD2@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158535_k127_638845_16	477974.Daud_1918	1.537e-15	80.0	COG2026@1|root,COG2026@2|Bacteria,1VQH9@1239|Firmicutes,25DE0@186801|Clostridia,2661M@186807|Peptococcaceae	186801|Clostridia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_638845_6	1229780.BN381_10122	2.889e-89	312.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,3UWNE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158535_k127_638845_5	404589.Anae109_2667	1.09e-93	337.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158535_k127_638845_14	710111.FraQA3DRAFT_2107	2.011e-35	155.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Methyltransf_11,Methyltransf_23
SRR25158535_k127_638845_12	357808.RoseRS_1724	1.318e-57	207.0	COG0110@1|root,COG0110@2|Bacteria,2G7B9@200795|Chloroflexi,376QA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158535_k127_638845_10	644282.Deba_0452	2.517e-66	246.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158535_k127_638845_20	596152.DesU5LDRAFT_0094	1.923e-12	80.0	COG1928@1|root,COG1928@2|Bacteria,1RBY3@1224|Proteobacteria,430BV@68525|delta/epsilon subdivisions,2WVW6@28221|Deltaproteobacteria,2MF10@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_638845_18	1120950.KB892790_gene2055	3.448e-13	74.0	2BRHF@1|root,32KGE@2|Bacteria,2H8PH@201174|Actinobacteria	201174|Actinobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
SRR25158535_k127_638845_17	1123024.AUII01000007_gene4839	3.115e-14	77.0	COG3620@1|root,COG3620@2|Bacteria,2GTMF@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158535_k127_638845_11	644282.Deba_0452	1.782e-61	239.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158535_k127_638845_8	1499967.BAYZ01000038_gene2273	2.649e-75	271.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158535_k127_638845_7	1499967.BAYZ01000038_gene2273	2.31e-83	293.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158535_k127_638845_19	457425.XNR_1943	1.888e-12	79.0	COG0840@1|root,COG0840@2|Bacteria,2IEDD@201174|Actinobacteria	201174|Actinobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_638845_0	1040989.AWZU01000009_gene1073	3.789e-206	676.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,2TTQP@28211|Alphaproteobacteria,3JU1W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158535_k127_639712_45	521096.Tpau_1067	9.867e-13	76.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_639712_32	1298863.AUEP01000001_gene949	1.345e-32	145.0	COG2385@1|root,COG2385@2|Bacteria,2I2J0@201174|Actinobacteria,4DQBJ@85009|Propionibacteriales	201174|Actinobacteria	D	PFAM Stage II sporulation D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SpoIID,VCBS
SRR25158535_k127_639712_48	429009.Adeg_0794	7.011e-11	75.0	COG1361@1|root,COG1361@2|Bacteria,1VPQQ@1239|Firmicutes,24WHC@186801|Clostridia,42HPA@68295|Thermoanaerobacterales	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_639712_43	592028.GCWU000321_00178	1.573e-17	96.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158535_k127_639712_9	383372.Rcas_1705	8.194e-109	359.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_639712_10	1128421.JAGA01000002_gene1343	4.733e-107	353.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158535_k127_639712_53	1463885.KL578369_gene5371	0.0004845	52.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase,VCBS
SRR25158535_k127_639712_12	1283299.AUKG01000002_gene5276	4.159e-95	336.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CR0F@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_639712_17	330214.NIDE1157	6.972e-78	275.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_639712_40	1192868.CAIU01000021_gene3078	4.069e-22	107.0	COG3832@1|root,COG3832@2|Bacteria,1RJ7U@1224|Proteobacteria,2U9W0@28211|Alphaproteobacteria,43KQ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_639712_31	876269.ARWA01000001_gene3594	8.344e-36	144.0	COG3832@1|root,COG3832@2|Bacteria,1N3W1@1224|Proteobacteria,2VFMP@28211|Alphaproteobacteria,3ND0M@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_639712_26	717785.HYPMC_3864	1.726e-46	169.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,3N8NC@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158535_k127_639712_51	335543.Sfum_1988	3.682e-06	55.0	COG1309@1|root,COG1309@2|Bacteria,1N7QG@1224|Proteobacteria,4347H@68525|delta/epsilon subdivisions,2X61R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158535_k127_639712_30	1121271.AUCM01000018_gene553	4.04e-36	156.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2TR0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_639712_52	1120949.KB903294_gene3633	9.481e-06	58.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158535_k127_639712_25	1144310.PMI07_006199	5.713e-52	203.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VFT3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_639712_27	103733.JNYO01000013_gene4250	2.703e-45	174.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4E1XR@85010|Pseudonocardiales	201174|Actinobacteria	Q	Chitin-binding domain type 3	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158535_k127_639712_16	1192034.CAP_2968	4.021e-90	315.0	COG4914@1|root,COG4914@2|Bacteria,1QX3W@1224|Proteobacteria,42ZWQ@68525|delta/epsilon subdivisions,2WVG3@28221|Deltaproteobacteria,2Z3HN@29|Myxococcales	28221|Deltaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SRR25158535_k127_639712_15	1540221.JQNI01000002_gene2895	3.595e-91	319.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_639712_34	765911.Thivi_0642	2.178e-29	127.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1RYMT@1236|Gammaproteobacteria,1WX70@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158535_k127_639712_49	2423.NA23_0201235	9.521e-11	74.0	COG0457@1|root,COG1672@1|root,COG2199@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2199@2|Bacteria,2GEFJ@200918|Thermotogae	200918|Thermotogae	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158535_k127_639712_19	580327.Tthe_2171	3.768e-70	255.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42F3X@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158535_k127_639712_22	635013.TherJR_0569	6.142e-64	241.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158535_k127_639712_38	469383.Cwoe_2409	2.218e-25	122.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158535_k127_639712_11	1122611.KB903975_gene3217	2.125e-106	366.0	COG3271@1|root,COG3271@2|Bacteria,2GM3Z@201174|Actinobacteria,4EGH9@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
SRR25158535_k127_639712_33	484770.UFO1_0404	7.203e-30	127.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4H45B@909932|Negativicutes	909932|Negativicutes	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158535_k127_639712_54	1121439.dsat_0098	0.0007525	51.0	COG4541@1|root,COG4541@2|Bacteria,1NJCY@1224|Proteobacteria,4367I@68525|delta/epsilon subdivisions,2X0RW@28221|Deltaproteobacteria,2MD87@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158535_k127_639712_50	1002340.AFCF01000075_gene3389	9.804e-08	65.0	2E3J0@1|root,32YHF@2|Bacteria,1N91F@1224|Proteobacteria,2UIR5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_639712_29	266117.Rxyl_2878	7.046e-38	149.0	COG0394@1|root,COG0394@2|Bacteria,2HEP3@201174|Actinobacteria,4CTHA@84995|Rubrobacteria	84995|Rubrobacteria	T	low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158535_k127_639712_35	67356.KL575653_gene4263	1.498e-28	130.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_639712_41	479434.Sthe_1360	1.032e-21	104.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi,27YB6@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_639712_14	671143.DAMO_1458	6.686e-95	326.0	COG1473@1|root,COG1473@2|Bacteria,2NP7P@2323|unclassified Bacteria	2|Bacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_639712_0	290397.Adeh_3676	3.331e-286	889.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
SRR25158535_k127_639712_4	1380347.JNII01000006_gene1592	1.057e-138	479.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158535_k127_639712_47	215803.DB30_1669	7.092e-12	71.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2Z1HI@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_639712_28	1150864.MILUP08_43948	9.137e-42	174.0	COG2072@1|root,COG2072@2|Bacteria,2GNGX@201174|Actinobacteria,4DAXR@85008|Micromonosporales	201174|Actinobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158535_k127_639712_2	926560.KE387027_gene419	1.036e-166	554.0	COG0477@1|root,COG0477@2|Bacteria,1WMC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_639712_20	1121380.JNIW01000058_gene11	1.777e-66	239.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158535_k127_639712_18	1449353.JQMQ01000005_gene422	5.733e-76	275.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,2NEDD@228398|Streptacidiphilus	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_639712_44	1243664.CAVL020000026_gene1155	2.024e-14	86.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,4HAGD@91061|Bacilli,1ZD2A@1386|Bacillus	91061|Bacilli	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR25158535_k127_639712_21	1171373.PACID_30520	3.737e-64	233.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DNRX@85009|Propionibacteriales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158535_k127_639712_23	1089552.KI911559_gene1303	4.505e-59	211.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,2JTZ5@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158535_k127_639712_24	1304275.C41B8_04291	7.774e-57	219.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,1RQDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	permease	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158535_k127_639712_6	469383.Cwoe_3265	1.843e-114	381.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CP6Z@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158535_k127_639712_42	926550.CLDAP_19950	4.01e-18	96.0	2E1CR@1|root,32WS9@2|Bacteria,2G8CY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_639712_46	2880.D8LHU5	2.516e-12	78.0	COG0664@1|root,KOG1113@2759|Eukaryota	2759|Eukaryota	T	cAMP-dependent protein kinase regulator activity	-	-	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158535_k127_639712_3	1382306.JNIM01000001_gene1290	1.438e-150	485.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158535_k127_639712_39	1293048.CBMB010000004_gene2186	3.046e-23	113.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_639712_5	685778.AORL01000010_gene2569	1.993e-117	389.0	COG3345@1|root,COG3345@2|Bacteria,1PNJQ@1224|Proteobacteria,2UP54@28211|Alphaproteobacteria,2KDDP@204457|Sphingomonadales	204457|Sphingomonadales	G	Alpha galactosidase A C-terminal beta sandwich domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,Melibiase_2_C
SRR25158535_k127_639712_7	349741.Amuc_1436	6.873e-113	373.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158535_k127_639712_36	716928.AJQT01000079_gene1049	2.104e-26	120.0	COG2202@1|root,COG2203@1|root,COG3290@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3920@2|Bacteria,1QQZ6@1224|Proteobacteria,2U3V1@28211|Alphaproteobacteria,4BFN9@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	HWE histidine kinase	exsG	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HWE_HK,PAS_3,PAS_4,PAS_9
SRR25158535_k127_639712_13	479434.Sthe_3406	5.302e-95	347.0	COG0477@1|root,COG0642@1|root,COG0793@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG0477@2|Bacteria,COG0793@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia	189775|Thermomicrobia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD
SRR25158535_k127_639712_8	671143.DAMO_1992	9.411e-112	368.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR25158535_k127_639712_1	351607.Acel_1865	2.787e-277	865.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158535_k127_671036_27	644966.Tmar_1733	3.619e-46	185.0	COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,25B0M@186801|Clostridia,3WDSJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158535_k127_671036_39	1123065.ATWL01000038_gene1788	1.949e-08	63.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_671036_36	1569209.BBPH01000076_gene250	5.948e-15	84.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,2PUST@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158535_k127_671036_21	1382306.JNIM01000001_gene1022	5.071e-63	236.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_671036_0	485913.Krac_2434	1.657e-305	959.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_671036_17	1382306.JNIM01000001_gene1024	3.733e-76	283.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_671036_33	1240350.AMZE01000004_gene2440	2.153e-18	94.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1S9Q1@1236|Gammaproteobacteria,1YVP8@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158535_k127_671036_23	591167.Sfla_1634	4.725e-61	231.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158535_k127_671036_15	1382356.JQMP01000001_gene1278	1.016e-77	274.0	COG0475@1|root,COG0475@2|Bacteria,2G6B0@200795|Chloroflexi,27Z31@189775|Thermomicrobia	189775|Thermomicrobia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_671036_35	1458357.BG58_38105	4.497e-18	89.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VWXW@28216|Betaproteobacteria,1KFFD@119060|Burkholderiaceae	28216|Betaproteobacteria	K	RNA polymerase	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_671036_30	479434.Sthe_2173	5.506e-36	156.0	COG0350@1|root,COG5662@1|root,COG0350@2|Bacteria,COG5662@2|Bacteria,2G98B@200795|Chloroflexi,27Z9T@189775|Thermomicrobia	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	cseE	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	zf-HC2
SRR25158535_k127_671036_26	1120950.KB892764_gene5618	2.613e-49	185.0	COG2197@1|root,COG2197@2|Bacteria,2I126@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_671036_8	1173022.Cri9333_4627	1.049e-99	334.0	COG1366@1|root,COG1366@2|Bacteria,1G1ZX@1117|Cyanobacteria,1H9T7@1150|Oscillatoriales	1117|Cyanobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
SRR25158535_k127_671036_24	204669.Acid345_2415	5.218e-51	183.0	COG1366@1|root,COG1366@2|Bacteria,3Y4YT@57723|Acidobacteria,2JJGC@204432|Acidobacteriia	204432|Acidobacteriia	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158535_k127_671036_28	63737.Npun_R2265	2.475e-45	173.0	COG2172@1|root,COG2172@2|Bacteria,1G668@1117|Cyanobacteria,1HQ42@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c
SRR25158535_k127_671036_14	1173027.Mic7113_3986	1.127e-82	291.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,1G02S@1117|Cyanobacteria,1H8SM@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
SRR25158535_k127_671036_1	221288.JH992901_gene1440	3.938e-247	782.0	COG0642@1|root,COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2205@2|Bacteria,1G2CJ@1117|Cyanobacteria,1JK5A@1189|Stigonemataceae	1117|Cyanobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158535_k127_671036_22	378806.STAUR_3490	4.704e-61	231.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1QUJ9@1224|Proteobacteria,42MEB@68525|delta/epsilon subdivisions,2X1ZE@28221|Deltaproteobacteria,2YWRB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158535_k127_671036_38	1306174.JODP01000006_gene3313	2.898e-09	67.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_671036_44	1476583.DEIPH_ctg018orf0016	4.442e-05	56.0	COG0454@1|root,COG0456@2|Bacteria,1WMXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_671036_18	1128421.JAGA01000002_gene261	5.095e-69	267.0	COG1319@1|root,COG1319@2|Bacteria,2NQUQ@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	yagS	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_671036_3	867903.ThesuDRAFT_01467	5.252e-222	721.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_671036_25	1128421.JAGA01000002_gene263	3.03e-50	184.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,TAT_signal
SRR25158535_k127_671036_7	316274.Haur_1203	3.175e-100	344.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158535_k127_671036_31	526227.Mesil_2999	2.969e-29	126.0	COG1993@1|root,COG1993@2|Bacteria,1WKB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRR25158535_k127_671036_32	525904.Tter_1553	1.55e-27	115.0	COG0239@1|root,COG0239@2|Bacteria,2NQ56@2323|unclassified Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158535_k127_671036_11	1227360.C176_11619	3.356e-92	316.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,26EEG@186818|Planococcaceae	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
SRR25158535_k127_671036_43	644283.Micau_0792	8.779e-06	59.0	COG0683@1|root,COG0683@2|Bacteria,2IBMB@201174|Actinobacteria,4DB7D@85008|Micromonosporales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_671036_12	639030.JHVA01000001_gene2668	1.264e-89	303.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_671036_5	1379698.RBG1_1C00001G0513	2.424e-116	388.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158535_k127_671036_34	1123325.JHUV01000009_gene410	2.246e-18	100.0	COG0066@1|root,COG0066@2|Bacteria,2G405@200783|Aquificae	200783|Aquificae	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158535_k127_671036_20	224324.aq_940	2.162e-64	245.0	COG0065@1|root,COG0065@2|Bacteria,2G3S3@200783|Aquificae	200783|Aquificae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158535_k127_671036_16	279714.FuraDRAFT_3267	1.454e-76	264.0	2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria,2W032@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_671036_19	485913.Krac_6385	2.706e-67	243.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_671036_41	1303518.CCALI_01929	4.847e-08	63.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRR25158535_k127_671036_40	1123508.JH636442_gene3944	2.172e-08	62.0	COG1977@1|root,COG1977@2|Bacteria,2J0X5@203682|Planctomycetes	203682|Planctomycetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158535_k127_671036_9	251221.35212629	2.499e-99	338.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_671036_10	1283299.AUKG01000005_gene146	1.422e-92	324.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4CREI@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_671036_13	469383.Cwoe_1564	8.034e-84	283.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CQ1Q@84995|Rubrobacteria	84995|Rubrobacteria	T	Response regulator receiver	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_671036_42	511051.CSE_04620	1.124e-07	62.0	2DZXU@1|root,32VMR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_671036_2	671143.DAMO_3037	2.252e-235	740.0	COG0129@1|root,COG0129@2|Bacteria,2NNSM@2323|unclassified Bacteria	2|Bacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158535_k127_671036_6	1379698.RBG1_1C00001G0516	1.381e-102	347.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158535_k127_671036_4	1121938.AUDY01000012_gene3703	1.755e-137	465.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3NE83@45667|Halobacillus	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_671036_37	1038859.AXAU01000011_gene2414	2.265e-11	74.0	COG3070@1|root,COG3070@2|Bacteria,1P6Z6@1224|Proteobacteria	1224|Proteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158535_k127_671036_29	1122989.KB898580_gene1634	3.414e-36	143.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,2G370@200643|Bacteroidia	976|Bacteroidetes	S	Mg2 transporter-C family protein	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158535_k127_682409_50	1384057.CD33_02190	0.0005282	52.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,3IYC3@400634|Lysinibacillus	91061|Bacilli	P	ABC transporter	ssuB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158535_k127_682409_22	1173263.Syn7502_03006	2.932e-53	207.0	COG0600@1|root,COG0600@2|Bacteria,1G1ZK@1117|Cyanobacteria,1GZMV@1129|Synechococcus	1117|Cyanobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158535_k127_682409_21	1283283.ATXA01000021_gene2855	3.283e-54	203.0	COG1335@1|root,COG1335@2|Bacteria,2IDT7@201174|Actinobacteria	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158535_k127_682409_11	1500257.JQNM01000014_gene2941	7.891e-88	302.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_682409_42	1122918.KB907272_gene2194	5.122e-09	68.0	COG0715@1|root,COG0715@2|Bacteria,1V86M@1239|Firmicutes,4I6K6@91061|Bacilli,26TFH@186822|Paenibacillaceae	91061|Bacilli	P	Nitrate ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158535_k127_682409_45	160799.PBOR_01670	6.391e-07	62.0	COG0715@1|root,COG0715@2|Bacteria,1V86M@1239|Firmicutes,4I6K6@91061|Bacilli,26TFH@186822|Paenibacillaceae	91061|Bacilli	P	Nitrate ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158535_k127_682409_38	485913.Krac_8723	6.967e-16	92.0	COG2059@1|root,COG2059@2|Bacteria	2|Bacteria	P	chromate transport	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_682409_39	232721.Ajs_2259	8.084e-15	89.0	COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2VQS5@28216|Betaproteobacteria,4ADPS@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_682409_4	1500257.JQNM01000014_gene2942	2.568e-100	344.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,2UQEU@28211|Alphaproteobacteria,4BJEW@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Ethanolamine utilisation protein EutA	-	-	-	-	-	-	-	-	-	-	-	-	EutA
SRR25158535_k127_682409_10	1500257.JQNM01000014_gene2941	1.873e-88	303.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_682409_47	194867.ALBQ01000044_gene1449	4.332e-06	56.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2UDE8@28211|Alphaproteobacteria,2K5WZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_682409_48	700598.Niako_2537	1.864e-05	51.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1IYYX@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_682409_3	1500306.JQLA01000004_gene5302	1.239e-108	370.0	COG0747@1|root,COG0747@2|Bacteria,1PUV0@1224|Proteobacteria,2TVJT@28211|Alphaproteobacteria,4BCGN@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_682409_8	158189.SpiBuddy_2516	1.941e-92	313.0	COG0601@1|root,COG0601@2|Bacteria,2J9KQ@203691|Spirochaetes	203691|Spirochaetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_682409_14	479434.Sthe_1511	6.114e-83	284.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_682409_43	215803.DB30_4808	8.98e-09	67.0	COG0454@1|root,COG0456@2|Bacteria,1Q9M5@1224|Proteobacteria,434GJ@68525|delta/epsilon subdivisions,2WYTX@28221|Deltaproteobacteria,2Z0KV@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_682409_1	1123023.JIAI01000013_gene3858	1.645e-159	544.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4DZHU@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD binding domain	-	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
SRR25158535_k127_682409_23	1232683.ADIMK_4114	9.263e-51	188.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1SYQ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158535_k127_682409_36	883078.HMPREF9695_00773	4.532e-25	123.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_682409_26	1120792.JAFV01000001_gene2271	1.503e-45	177.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TRVI@28211|Alphaproteobacteria,370NJ@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SRR25158535_k127_682409_17	1123023.JIAI01000001_gene6559	2.415e-69	266.0	COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria,4E3K5@85010|Pseudonocardiales	201174|Actinobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158535_k127_682409_9	234267.Acid_7160	3.872e-92	319.0	COG0154@1|root,COG0154@2|Bacteria,3Y6WA@57723|Acidobacteria	57723|Acidobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158535_k127_682409_49	1121106.JQKB01000003_gene2483	4.694e-05	49.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_682409_0	1380390.JIAT01000012_gene3140	1.123e-181	582.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CR5C@84995|Rubrobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_682409_46	1157635.KB892013_gene2463	2.107e-06	59.0	COG0454@1|root,COG0456@2|Bacteria,2GKQU@201174|Actinobacteria	201174|Actinobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158535_k127_682409_15	1207076.ALAT01000207_gene1734	2.529e-80	278.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1Z1ZX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_682409_12	113395.AXAI01000008_gene1165	5.291e-85	293.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,3JQTR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	MA20_01210	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_682409_34	266117.Rxyl_0369	1.241e-30	136.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4CTCQ@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM luciferase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_682409_35	1240349.ANGC01000015_gene712	2.546e-26	123.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,4FVAC@85025|Nocardiaceae	201174|Actinobacteria	EGP	MFS/sugar transport protein	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158535_k127_682409_13	479434.Sthe_0680	1.061e-84	312.0	COG0747@1|root,COG0747@2|Bacteria,2GAP8@200795|Chloroflexi,27YXK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_682409_16	479434.Sthe_2446	9.659e-75	269.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_682409_20	2002.JOEQ01000026_gene352	9.483e-56	217.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158535_k127_682409_27	1183438.GKIL_3324	3.803e-44	177.0	COG0477@1|root,COG2814@2|Bacteria,1G2N2@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_682409_2	986075.CathTA2_1639	1.13e-140	467.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli	1239|Firmicutes	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
SRR25158535_k127_682409_7	479434.Sthe_0680	2.522e-94	330.0	COG0747@1|root,COG0747@2|Bacteria,2GAP8@200795|Chloroflexi,27YXK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_682409_6	2340.JV46_12010	1.817e-94	317.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1J5TX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158535_k127_682409_18	525904.Tter_1985	3.475e-64	234.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158535_k127_682409_30	443218.AS9A_1670	2.141e-39	156.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,23B39@1762|Mycobacteriaceae	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158535_k127_682409_19	933262.AXAM01000036_gene2177	1.463e-62	221.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_682409_32	1214101.BN159_4301	3.089e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,2H45C@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_682409_40	743718.Isova_0560	3.805e-13	79.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_682409_25	1214101.BN159_4299	4.469e-50	193.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158535_k127_682409_41	1214101.BN159_4299	4.321e-10	62.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158535_k127_682409_29	1283283.ATXA01000001_gene329	5.029e-41	168.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria,4EUHD@85013|Frankiales	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158535_k127_682409_5	40571.JOEA01000027_gene5927	1.973e-98	349.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria,4EAAX@85010|Pseudonocardiales	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158535_k127_682409_28	926554.KI912653_gene4147	1.598e-42	179.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_682409_37	113395.AXAI01000002_gene5239	2.499e-19	89.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_695707_2	208439.AJAP_07105	5.289e-147	488.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_695707_21	1125863.JAFN01000001_gene381	2.777e-42	172.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SRR25158535_k127_695707_17	1127134.NOCYR_0566	1.315e-54	200.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FWYQ@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_695707_20	1232410.KI421420_gene3143	9.002e-43	171.0	COG4936@1|root,COG5002@1|root,COG4936@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WM5B@28221|Deltaproteobacteria,43U8X@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR25158535_k127_695707_19	316274.Haur_3775	4.085e-51	196.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158535_k127_695707_3	1128421.JAGA01000002_gene991	4.349e-145	478.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158535_k127_695707_4	118168.MC7420_5670	8.895e-106	358.0	COG3875@1|root,COG3875@2|Bacteria,1G82E@1117|Cyanobacteria,1HDBH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158535_k127_695707_5	1499967.BAYZ01000054_gene4816	6.255e-103	357.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_695707_8	292.DM42_6646	4.652e-83	289.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,1K1SR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158535_k127_695707_37	1123269.NX02_03720	1.189e-11	78.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,2K6G9@204457|Sphingomonadales	204457|Sphingomonadales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_695707_22	656024.FsymDg_3257	9.644e-40	164.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4ESEC@85013|Frankiales	201174|Actinobacteria	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158535_k127_695707_16	479434.Sthe_3364	2.177e-58	227.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158535_k127_695707_12	479434.Sthe_3365	1.713e-66	237.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_695707_10	324602.Caur_1786	8.551e-75	270.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,375R7@32061|Chloroflexia	32061|Chloroflexia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158535_k127_695707_7	867903.ThesuDRAFT_02027	6.882e-97	344.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WCFU@538999|Clostridiales incertae sedis	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
SRR25158535_k127_695707_43	671143.DAMO_1319	0.000166	55.0	COG0457@1|root,COG3712@1|root,COG4773@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	FecR,Plug,STN,TPR_16,TPR_8,TonB_dep_Rec
SRR25158535_k127_695707_39	435908.IDSA_01420	3.749e-06	59.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,2QFCC@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmI	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_2
SRR25158535_k127_695707_34	246200.SPOA0196	7.781e-19	99.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	subunit of a heme lyase	cycL	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158535_k127_695707_26	215803.DB30_1964	1.251e-34	153.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158535_k127_695707_1	671143.DAMO_1588	2.615e-152	510.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198,ko:K04016	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158535_k127_695707_30	314266.SKA58_10713	7.244e-23	104.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2K56Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158535_k127_695707_13	477641.MODMU_1606	1.744e-64	243.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158535_k127_695707_35	1123388.AQWU01000041_gene461	1.005e-17	96.0	COG2386@1|root,COG2386@2|Bacteria,1WIH9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ABC-type transport system involved in cytochrome c biogenesis permease component	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158535_k127_695707_28	663610.JQKO01000002_gene1257	1.085e-24	113.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,3NAZD@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158535_k127_695707_41	1434325.AZQN01000001_gene204	5.036e-06	56.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NKGP@976|Bacteroidetes,47M97@768503|Cytophagia	976|Bacteroidetes	C	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158535_k127_695707_23	485913.Krac_9334	3.666e-39	154.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158535_k127_695707_11	1120949.KB903357_gene4802	1.535e-68	265.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4D8Q0@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_695707_0	644966.Tmar_1167	5.436e-211	675.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WCRP@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158535_k127_695707_25	395492.Rleg2_3510	1.066e-35	146.0	COG4221@1|root,COG4221@2|Bacteria,1QXBX@1224|Proteobacteria,2TX88@28211|Alphaproteobacteria,4BCSG@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_695707_9	941639.BCO26_0729	4.209e-79	283.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_695707_36	1121430.JMLG01000002_gene1254	5.664e-15	80.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,24P9J@186801|Clostridia,262J0@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158535_k127_695707_40	326427.Cagg_3705	4.368e-06	60.0	COG1432@1|root,COG3266@1|root,COG1432@2|Bacteria,COG3266@2|Bacteria,2G7FF@200795|Chloroflexi,3755W@32061|Chloroflexia	32061|Chloroflexia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158535_k127_695707_6	1219084.AP014508_gene1434	2.073e-101	347.0	COG0312@1|root,COG0312@2|Bacteria,2GDC4@200918|Thermotogae	200918|Thermotogae	L	modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_695707_14	1379698.RBG1_1C00001G1510	2.823e-61	233.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_695707_29	290397.Adeh_1404	3.807e-23	105.0	COG5592@1|root,COG5592@2|Bacteria,1ND3D@1224|Proteobacteria,437AR@68525|delta/epsilon subdivisions,2X9YU@28221|Deltaproteobacteria,2Z279@29|Myxococcales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158535_k127_695707_31	1128421.JAGA01000002_gene1632	1.027e-20	102.0	COG1276@1|root,COG2010@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2010@2|Bacteria,COG2372@2|Bacteria,2NPS1@2323|unclassified Bacteria	2|Bacteria	P	Evidence 5 No homology to any previously reported sequences	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD,Cytochrome_CBB3,YtkA
SRR25158535_k127_695707_33	477641.MODMU_1283	1.941e-19	103.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4ESVK@85013|Frankiales	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158535_k127_695707_27	525904.Tter_1119	1.118e-29	125.0	arCOG08811@1|root,32UTS@2|Bacteria,2NR80@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_695707_15	479434.Sthe_1818	4.812e-60	233.0	COG2042@1|root,COG3376@2|Bacteria	2|Bacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SRR25158535_k127_695707_24	1050202.KB913024_gene1020	3.856e-36	157.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,409WN@622450|Actinopolysporales	201174|Actinobacteria	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158535_k127_695707_32	266940.Krad_3370	1.092e-19	94.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158535_k127_695707_18	204669.Acid345_3196	4.047e-53	198.0	COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia	204432|Acidobacteriia	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
SRR25158535_k127_695707_38	857293.CAAU_2128	6.352e-07	61.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF1858,Hemerythrin
SRR25158535_k127_700994_4	1231391.AMZF01000110_gene916	8.782e-144	468.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_700994_41	1048339.KB913029_gene2505	1.247e-16	83.0	COG0640@1|root,COG0640@2|Bacteria,2IRF0@201174|Actinobacteria,4EWG5@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158535_k127_700994_34	351607.Acel_0525	2.193e-22	103.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EWZZ@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158535_k127_700994_42	1156937.MFUM_550027	2.735e-16	87.0	COG0425@1|root,COG0425@2|Bacteria,46YZR@74201|Verrucomicrobia,37GVP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR25158535_k127_700994_6	1521187.JPIM01000137_gene2066	4.498e-138	453.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_700994_37	1108045.GORHZ_118_00110	2.098e-19	89.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
SRR25158535_k127_700994_26	710696.Intca_2822	3.513e-42	177.0	COG2210@1|root,COG2210@2|Bacteria,2IGW8@201174|Actinobacteria	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158535_k127_700994_1	1128421.JAGA01000003_gene3550	4.14e-174	557.0	COG0277@1|root,COG0277@2|Bacteria,2NQTQ@2323|unclassified Bacteria	2|Bacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_700994_13	1120950.KB892708_gene4367	2.462e-93	318.0	COG0491@1|root,COG0491@2|Bacteria,2HP5U@201174|Actinobacteria,4DT4G@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_700994_28	1380386.JIAW01000030_gene3587	1.439e-37	161.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	yecD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158535_k127_700994_10	469383.Cwoe_4113	3.11e-98	358.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CPP1@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_700994_39	1137268.AZXF01000011_gene3675	7.625e-18	96.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4EPRP@85012|Streptosporangiales	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158535_k127_700994_27	1123504.JQKD01000007_gene3483	2.496e-38	159.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,4AJ77@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_700994_25	1206720.BAFQ01000280_gene5887	1.068e-49	183.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4FWH1@85025|Nocardiaceae	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3,1.5.99.4	ko:K03518,ko:K19819	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_700994_23	309801.trd_A0575	2.733e-55	212.0	COG0477@1|root,COG2814@2|Bacteria,2GBHK@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_700994_40	40571.JOEA01000014_gene2105	8.71e-17	94.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4E0Y2@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_700994_17	349521.HCH_02499	2.474e-72	261.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales	135619|Oceanospirillales	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRR25158535_k127_700994_44	1123355.JHYO01000014_gene1047	6.134e-14	78.0	COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,2UDB6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_700994_35	324602.Caur_0190	6.813e-21	103.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158535_k127_700994_24	383372.Rcas_0246	8.306e-50	197.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,375AZ@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158535_k127_700994_3	1125863.JAFN01000001_gene298	2.964e-145	476.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158535_k127_700994_33	945713.IALB_3189	2.127e-27	128.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158535_k127_700994_7	326427.Cagg_0203	1.912e-126	436.0	COG2170@1|root,COG2170@2|Bacteria,2G5NR@200795|Chloroflexi,375BI@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158535_k127_700994_8	1521187.JPIM01000025_gene1118	1.326e-111	388.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158535_k127_700994_12	926550.CLDAP_22640	1.395e-95	326.0	COG0189@1|root,COG0189@2|Bacteria,2G864@200795|Chloroflexi	200795|Chloroflexi	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_700994_19	926550.CLDAP_22650	8.149e-70	254.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158535_k127_700994_22	246197.MXAN_3552	5.819e-60	215.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2YV9J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158535_k127_700994_31	1463853.JOHW01000055_gene5891	3.47e-32	137.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_700994_14	1382304.JNIL01000001_gene1074	2.977e-85	291.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,278VD@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158535_k127_700994_18	1382304.JNIL01000001_gene1075	4.306e-72	276.0	COG0388@1|root,COG0388@2|Bacteria,1UHWF@1239|Firmicutes,4HEQ4@91061|Bacilli,279EQ@186823|Alicyclobacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158535_k127_700994_0	1382306.JNIM01000001_gene1224	1.345e-273	865.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158535_k127_700994_47	497964.CfE428DRAFT_6532	2.491e-05	56.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TQ1@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158535_k127_700994_38	926569.ANT_17920	2.235e-18	94.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158535_k127_700994_21	309801.trd_0379	5.183e-65	238.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_700994_2	1283283.ATXA01000001_gene930	1.258e-160	537.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4ERKY@85013|Frankiales	201174|Actinobacteria	O	TIGRFAM FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_700994_29	309801.trd_0377	1.226e-36	159.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,27YGN@189775|Thermomicrobia	189775|Thermomicrobia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158535_k127_700994_5	1128421.JAGA01000002_gene1806	1.298e-142	477.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158535_k127_700994_11	926569.ANT_17980	1.864e-96	329.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158535_k127_700994_30	264732.Moth_1653	6.017e-34	147.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,42GCN@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM transcriptional regulator, Rrf2 family	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158535_k127_700994_32	379066.GAU_2760	6.715e-31	135.0	COG1986@1|root,COG1986@2|Bacteria,1ZUVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
SRR25158535_k127_700994_45	436308.Nmar_1102	2.331e-13	74.0	COG3794@1|root,arCOG06255@1|root,arCOG02926@2157|Archaea,arCOG06255@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158535_k127_700994_20	1382356.JQMP01000003_gene2439	7.629e-69	244.0	COG1173@1|root,COG1173@2|Bacteria,2GBDG@200795|Chloroflexi,27YY2@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_700994_16	857293.CAAU_0436	4.235e-79	275.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_700994_15	1382356.JQMP01000003_gene2441	2.162e-81	300.0	COG0747@1|root,COG0747@2|Bacteria,2GA2U@200795|Chloroflexi,27YVV@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_700994_9	1382356.JQMP01000004_gene644	3.736e-111	362.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_732700_14	690597.JH730983_gene163	8.812e-21	105.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,1RPFC@1236|Gammaproteobacteria,1YQR7@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	EGP	Transporter	stp_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_732700_6	1449049.JONW01000010_gene3748	1.174e-76	274.0	COG0624@1|root,COG0624@2|Bacteria,1MV5P@1224|Proteobacteria,2U0Z8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_732700_5	1123073.KB899243_gene722	4.759e-108	390.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RMY2@1236|Gammaproteobacteria,1XDBK@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_732700_3	316058.RPB_4416	1.322e-148	507.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158535_k127_732700_11	273063.STK_17820	2.971e-45	175.0	COG2080@1|root,arCOG01925@2157|Archaea,2XQC1@28889|Crenarchaeota	28889|Crenarchaeota	C	2Fe-2S -binding domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114	1.2.5.3,1.2.99.8	ko:K03518,ko:K18022	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R10324,R11168	RC00242,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_732700_9	316058.RPB_4414	3.869e-53	201.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3K3D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_732700_15	292459.STH3146	3.446e-16	85.0	COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia	186801|Clostridia	C	PFAM Rieske 2Fe-2S domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158535_k127_732700_8	408672.NBCG_01967	5.212e-56	208.0	COG0515@1|root,COG0515@2|Bacteria,2IAFS@201174|Actinobacteria,4DQXW@85009|Propionibacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_732700_7	760568.Desku_0581	1.686e-71	256.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia	186801|Clostridia	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.2.1.5	ko:K01683	-	-	-	-	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_732700_13	867903.ThesuDRAFT_02291	4.684e-29	128.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3WCMW@538999|Clostridiales incertae sedis	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158535_k127_732700_0	479434.Sthe_0845	2.916e-248	783.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158535_k127_732700_16	1128421.JAGA01000003_gene3161	0.0001105	54.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	rskA	GO:0000988,GO:0000989,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016989,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158535_k127_732700_10	266117.Rxyl_1667	4.299e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CQ93@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_732700_1	357808.RoseRS_0142	1.333e-209	675.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,3753T@32061|Chloroflexia	32061|Chloroflexia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158535_k127_732700_12	747365.Thena_0469	3.952e-31	141.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia,42GK2@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
SRR25158535_k127_732700_2	1341151.ASZU01000006_gene2816	7.298e-199	641.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,27B92@186824|Thermoactinomycetaceae	91061|Bacilli	L	breast cancer carboxy-terminal domain	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158535_k127_732700_4	1128421.JAGA01000002_gene1253	6.775e-129	422.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158535_k127_743375_10	644283.Micau_2759	1.714e-65	228.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4D8MM@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_743375_14	272134.KB731326_gene172	3.472e-48	178.0	COG4925@1|root,COG4925@2|Bacteria,1GFK4@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG4925 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Cyclophil_like
SRR25158535_k127_743375_20	1121272.KB903291_gene3329	6.494e-23	106.0	2BKAB@1|root,32EQK@2|Bacteria,2GXJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_743375_2	1194165.CAJF01000022_gene3132	3.862e-125	417.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4FR3Z@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_743375_11	869210.Marky_1632	1.028e-63	230.0	COG0491@1|root,COG0491@2|Bacteria,1WJDH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_743375_15	204669.Acid345_3130	7.258e-40	156.0	COG1392@1|root,COG1392@2|Bacteria,3Y58U@57723|Acidobacteria,2JK4H@204432|Acidobacteriia	204432|Acidobacteriia	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158535_k127_743375_6	596152.DesU5LDRAFT_3674	8.63e-103	344.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,2M950@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158535_k127_743375_3	525904.Tter_2868	1.386e-114	390.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158535_k127_743375_13	1094508.Tsac_0443	1.918e-61	243.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,42ESX@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	walR	-	-	ko:K07658,ko:K07667,ko:K07668,ko:K07776	ko02020,ko02024,map02020,map02024	M00434,M00443,M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_743375_4	555079.Toce_0354	2.24e-107	359.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,42EPR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM extracellular solute-binding protein family 1	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	Big_5,PBP_like_2
SRR25158535_k127_743375_7	926550.CLDAP_00830	2.746e-99	337.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158535_k127_743375_8	1122919.KB905563_gene2539	5.49e-87	305.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,26U7E@186822|Paenibacillaceae	91061|Bacilli	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158535_k127_743375_5	309801.trd_1829	1.89e-104	360.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,27YZP@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158535_k127_743375_12	1382356.JQMP01000004_gene657	1.567e-61	228.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,27XPS@189775|Thermomicrobia	189775|Thermomicrobia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158535_k127_743375_23	1297617.JPJD01000041_gene1835	1.332e-20	94.0	COG0350@1|root,COG0350@2|Bacteria,1UMXH@1239|Firmicutes,25GRS@186801|Clostridia,26CJF@186813|unclassified Clostridiales	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR25158535_k127_743375_22	1120949.KB903315_gene148	7.134e-21	99.0	COG1695@1|root,COG1695@2|Bacteria,2GRVH@201174|Actinobacteria,4DJQ9@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_743375_26	1356854.N007_11050	8.018e-06	58.0	2EUC9@1|root,33MUN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_743375_25	1163409.UUA_03563	5.005e-07	59.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158535_k127_743375_1	1122138.AQUZ01000019_gene8140	7.327e-136	456.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DP46@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
SRR25158535_k127_743375_16	644966.Tmar_0210	3.726e-35	154.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158535_k127_743375_17	498761.HM1_2189	9.846e-35	140.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158535_k127_743375_18	479434.Sthe_2016	1.182e-34	138.0	COG0073@1|root,COG0073@2|Bacteria,2G74R@200795|Chloroflexi,27YK6@189775|Thermomicrobia	189775|Thermomicrobia	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR25158535_k127_743375_21	1382306.JNIM01000001_gene2483	2.46e-21	99.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SRR25158535_k127_743375_9	1382304.JNIL01000001_gene3204	1.124e-69	248.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158535_k127_743375_24	1173263.Syn7502_01511	1.451e-20	101.0	COG0515@1|root,COG0515@2|Bacteria,1GA6I@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158535_k127_743375_0	1382356.JQMP01000003_gene2026	4.76e-138	458.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,27XPN@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158535_k127_743375_19	1125712.HMPREF1316_0778	1.076e-31	132.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CYGS@84998|Coriobacteriia	84998|Coriobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_749871_1	867845.KI911784_gene1949	1.463e-80	275.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_749871_3	771875.Ferpe_1427	3.487e-18	99.0	COG0477@1|root,COG2814@2|Bacteria,2GCFM@200918|Thermotogae	200918|Thermotogae	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158535_k127_749871_4	1041930.Mtc_2197	2.083e-13	84.0	COG3729@1|root,arCOG10926@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_749871_0	309801.trd_0392	4.087e-94	323.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158535_k127_749871_2	316274.Haur_3075	9.395e-22	109.0	COG2251@1|root,COG2251@2|Bacteria	2|Bacteria	-	-	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	AAA_11,AAA_12,AAA_30,DUF2779,RNase_H_2
SRR25158535_k127_769405_5	331869.BAL199_09795	2.525e-71	254.0	COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,2TY3S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158535_k127_769405_13	1408428.JNJP01000060_gene856	5.224e-23	114.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2M7YN@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158535_k127_769405_6	1128421.JAGA01000002_gene1825	2.266e-56	209.0	COG1694@1|root,COG3956@2|Bacteria,2NP9V@2323|unclassified Bacteria	2|Bacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG,TP_methylase
SRR25158535_k127_769405_4	290397.Adeh_3361	2.988e-73	267.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria,2YUXF@29|Myxococcales	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158535_k127_769405_9	869210.Marky_0384	6.217e-37	160.0	COG0127@1|root,COG0127@2|Bacteria,1WJCE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158535_k127_769405_1	1206741.BAFX01000066_gene5304	5.42e-134	441.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4FVD0@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_769405_14	1192034.CAP_0198	1.754e-22	107.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_769405_15	1032480.MLP_00400	7.737e-21	96.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,4DSEC@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_769405_8	1163407.UU7_16382	1.671e-43	166.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,1SBHQ@1236|Gammaproteobacteria,1X6JD@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158535_k127_769405_17	35754.JNYJ01000078_gene7849	6.255e-17	94.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158535_k127_769405_0	378806.STAUR_5417	3.319e-189	617.0	COG2409@1|root,COG2409@2|Bacteria,1R9Z8@1224|Proteobacteria	1224|Proteobacteria	S	MMPL family	ydfJ	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_769405_16	926550.CLDAP_15440	3.271e-17	93.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,Flg_new,GPDPase_memb
SRR25158535_k127_769405_20	1128421.JAGA01000002_gene1061	4.474e-05	56.0	2EQIM@1|root,33I4N@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158535_k127_769405_12	383372.Rcas_2511	1.773e-24	120.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158535_k127_769405_2	1128421.JAGA01000002_gene1058	5.312e-105	350.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_769405_3	1128421.JAGA01000002_gene1057	8.939e-93	333.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158535_k127_769405_18	101510.RHA1_ro05001	2.906e-16	86.0	COG0745@1|root,COG0745@2|Bacteria,2GNFH@201174|Actinobacteria,4FW3F@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	prrA	GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944	-	ko:K07671	ko02020,map02020	M00462	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_769405_7	1128421.JAGA01000002_gene1616	2.84e-55	205.0	COG1300@1|root,COG1300@2|Bacteria	2|Bacteria	CP	Membrane	-	-	-	ko:K06384	-	-	-	-	ko00000	-	-	-	SpoIIM
SRR25158535_k127_769405_10	1521187.JPIM01000139_gene2214	4.989e-34	140.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158535_k127_769405_19	1177179.A11A3_03994	1.881e-08	57.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales	135619|Oceanospirillales	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_769405_21	593750.Metfor_1237	0.0003509	52.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158535_k127_769405_11	526225.Gobs_3888	7.781e-31	134.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_769777_0	986075.CathTA2_1639	1.739e-142	479.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli	1239|Firmicutes	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
SRR25158535_k127_769777_2	525904.Tter_1733	2.095e-48	184.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158535_k127_769777_7	525904.Tter_1734	1.983e-20	104.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
SRR25158535_k127_769777_4	292459.STH2617	5.58e-35	146.0	COG1670@1|root,COG1670@2|Bacteria,1V1G0@1239|Firmicutes,24SV9@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_8
SRR25158535_k127_769777_5	796942.HMPREF9623_01499	1.416e-29	134.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,248T4@186801|Clostridia	186801|Clostridia	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
SRR25158535_k127_769777_1	292459.STH2927	1.271e-97	328.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,24EJB@186801|Clostridia	186801|Clostridia	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_769777_3	926567.TheveDRAFT_0552	2.389e-35	144.0	COG0491@1|root,COG0491@2|Bacteria,3TAUB@508458|Synergistetes	508458|Synergistetes	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_769777_8	762376.AXYL_04697	1.464e-06	51.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2W09W@28216|Betaproteobacteria,3T6CP@506|Alcaligenaceae	28216|Betaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_831469_15	555088.DealDRAFT_2165	3.104e-42	159.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae	186801|Clostridia	J	elongation factor Tu domain 2 protein	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158535_k127_831469_6	1158318.ATXC01000001_gene573	5.857e-86	291.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158535_k127_831469_19	1121943.KB899991_gene2463	1.232e-25	123.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XJW7@135619|Oceanospirillales	135619|Oceanospirillales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158535_k127_831469_16	765420.OSCT_0160	3.98e-34	145.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,3774D@32061|Chloroflexia	32061|Chloroflexia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158535_k127_831469_5	383372.Rcas_1134	2.048e-104	354.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,3756H@32061|Chloroflexia	32061|Chloroflexia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158535_k127_831469_25	411471.SUBVAR_05253	2.46e-16	89.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WJZN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158535_k127_831469_1	1121468.AUBR01000029_gene1569	5.197e-202	647.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158535_k127_831469_22	1430331.EP10_17190	5.717e-19	91.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1WGHF@129337|Geobacillus	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158535_k127_831469_11	867903.ThesuDRAFT_00231	2.633e-49	192.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WCIW@538999|Clostridiales incertae sedis	186801|Clostridia	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158535_k127_831469_12	1382306.JNIM01000001_gene2748	1.121e-48	195.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
SRR25158535_k127_831469_9	867903.ThesuDRAFT_00229	1.929e-62	243.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3WCIC@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158535_k127_831469_18	266117.Rxyl_1417	1.904e-27	119.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158535_k127_831469_0	926569.ANT_10570	2.512e-229	732.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158535_k127_831469_13	661478.OP10G_0829	2.95e-48	181.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_831469_24	637389.Acaty_c2075	1.503e-16	93.0	COG3394@1|root,COG3394@2|Bacteria,1MX3P@1224|Proteobacteria,1RRC4@1236|Gammaproteobacteria,2NBYA@225057|Acidithiobacillales	225057|Acidithiobacillales	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
SRR25158535_k127_831469_20	1297742.A176_04915	2.172e-23	115.0	COG2230@1|root,COG2230@2|Bacteria,1NBKG@1224|Proteobacteria,433NZ@68525|delta/epsilon subdivisions,2WXUU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Methyltransferase domain	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
SRR25158535_k127_831469_7	525904.Tter_0795	3.504e-63	223.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158535_k127_831469_2	485913.Krac_12565	6.995e-191	612.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158535_k127_831469_3	1121468.AUBR01000009_gene2169	7.861e-124	445.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158535_k127_831469_21	383372.Rcas_1282	1.144e-20	108.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi,375R5@32061|Chloroflexia	32061|Chloroflexia	S	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158535_k127_831469_27	324602.Caur_1190	0.0007727	50.0	COG0558@1|root,COG0558@2|Bacteria,2GASR@200795|Chloroflexi,3778P@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158535_k127_831469_17	671143.DAMO_2618	1.969e-32	138.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158535_k127_831469_14	485913.Krac_4790	4.803e-47	185.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_831469_8	479434.Sthe_1548	1.904e-62	235.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi,27XVI@189775|Thermomicrobia	189775|Thermomicrobia	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
SRR25158535_k127_831469_4	383372.Rcas_3187	3.009e-123	411.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,37577@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
SRR25158535_k127_831469_26	329726.AM1_5431	3.044e-06	58.0	2ECD7@1|root,300UY@2|Bacteria,1G65B@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_831469_23	926569.ANT_10760	7.365e-17	81.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158535_k127_855414_28	401526.TcarDRAFT_0671	8.777e-30	123.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,4H4QB@909932|Negativicutes	909932|Negativicutes	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_855414_1	479434.Sthe_1721	2.369e-249	805.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158535_k127_855414_10	867903.ThesuDRAFT_02366	1.222e-78	273.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WCG4@538999|Clostridiales incertae sedis	186801|Clostridia	D	ATPases associated with a variety of cellular activities	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158535_k127_855414_24	861450.HMPREF0080_01202	6.931e-42	174.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158535_k127_855414_32	429009.Adeg_0030	2.125e-24	120.0	COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,42FT7@68295|Thermoanaerobacterales	186801|Clostridia	M	G5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
SRR25158535_k127_855414_20	357808.RoseRS_0189	1.878e-48	178.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi,375K8@32061|Chloroflexia	32061|Chloroflexia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158535_k127_855414_36	243365.CV_0552	2.523e-22	111.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,2VPGS@28216|Betaproteobacteria,2KQSR@206351|Neisseriales	206351|Neisseriales	EG	EamA-like transporter family	-	-	-	ko:K15269	-	-	-	-	ko00000,ko02000	2.A.7.3.3	-	-	EamA
SRR25158535_k127_855414_37	694429.Pyrfu_1520	1.352e-21	98.0	COG1324@1|root,arCOG04231@2157|Archaea,2XR6Y@28889|Crenarchaeota	28889|Crenarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158535_k127_855414_43	1048339.KB913029_gene571	2.364e-06	59.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4ETG9@85013|Frankiales	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
SRR25158535_k127_855414_41	225849.swp_0420	2.046e-09	70.0	COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria	1224|Proteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158535_k127_855414_46	309801.trd_A0617	4.835e-05	51.0	COG4961@1|root,COG4961@2|Bacteria,2GBBK@200795|Chloroflexi,27YP1@189775|Thermomicrobia	189775|Thermomicrobia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_855414_47	243090.RB1153	0.0007529	49.0	COG4961@1|root,COG4961@2|Bacteria,2J16N@203682|Planctomycetes	203682|Planctomycetes	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_855414_40	479434.Sthe_2622	6.715e-12	79.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158535_k127_855414_11	765420.OSCT_0533	1.09e-71	248.0	COG0745@1|root,COG0745@2|Bacteria,2GAJP@200795|Chloroflexi,37683@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_855414_15	326427.Cagg_2708	1.173e-54	218.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_855414_34	1356854.N007_11055	5.364e-24	104.0	COG1695@1|root,COG1695@2|Bacteria,1VC2Z@1239|Firmicutes,4HINE@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_855414_48	1120949.KB903315_gene149	0.0008778	50.0	2B94P@1|root,322FM@2|Bacteria,2H6UB@201174|Actinobacteria,4DJBV@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_855414_26	485913.Krac_8460	3.688e-32	136.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158535_k127_855414_22	357808.RoseRS_0398	2.203e-43	178.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_855414_27	1226322.HMPREF1545_04117	9.896e-32	143.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,2N69H@216572|Oscillospiraceae	186801|Clostridia	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158535_k127_855414_19	485913.Krac_8805	1.853e-49	194.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158535_k127_855414_33	867903.ThesuDRAFT_00472	2.7e-24	109.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WDPC@538999|Clostridiales incertae sedis	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158535_k127_855414_45	1123072.AUDH01000013_gene1502	3.86e-05	51.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158535_k127_855414_39	1121382.JQKG01000010_gene4696	5.159e-13	70.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158535_k127_855414_3	1128421.JAGA01000002_gene1335	1.091e-155	506.0	COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158535_k127_855414_6	357808.RoseRS_4406	2.202e-106	357.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,374SP@32061|Chloroflexia	32061|Chloroflexia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158535_k127_855414_13	765420.OSCT_2193	1.709e-57	214.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi,375E0@32061|Chloroflexia	32061|Chloroflexia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158535_k127_855414_44	1128421.JAGA01000004_gene2614	1.85e-05	58.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_855414_17	479434.Sthe_1778	1.26e-53	198.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	189775|Thermomicrobia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158535_k127_855414_29	1210046.B277_07356	8.331e-29	121.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4FGHI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158535_k127_855414_7	357808.RoseRS_0406	1.366e-104	358.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,3751B@32061|Chloroflexia	32061|Chloroflexia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158535_k127_855414_16	370438.PTH_1466	3.985e-54	200.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,267CB@186807|Peptococcaceae	186801|Clostridia	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_855414_31	644966.Tmar_0446	4.69e-25	113.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WCP8@538999|Clostridiales incertae sedis	186801|Clostridia	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158535_k127_855414_18	446468.Ndas_0251	4.084e-51	197.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria	201174|Actinobacteria	S	membrane	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158535_k127_855414_4	1150864.MILUP08_45590	2.264e-136	458.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D9CY@85008|Micromonosporales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
SRR25158535_k127_855414_23	644283.Micau_4833	6.42e-43	180.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4D9JP@85008|Micromonosporales	201174|Actinobacteria	P	cobalt transport	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158535_k127_855414_35	1254432.SCE1572_22950	1.776e-23	117.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_855414_21	1034769.KB910518_gene4333	1.082e-44	189.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4HNW3@91061|Bacilli,27548@186822|Paenibacillaceae	91061|Bacilli	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2,PMT_4TMC
SRR25158535_k127_855414_30	937777.Deipe_1368	6.685e-27	128.0	COG0631@1|root,COG0631@2|Bacteria,1WIBX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158535_k127_855414_12	309801.trd_1313	3.494e-65	239.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_855414_25	867845.KI911784_gene3681	9.1e-39	168.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158535_k127_855414_2	479434.Sthe_2436	1.012e-187	616.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158535_k127_855414_5	266117.Rxyl_0050	3.942e-117	396.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4CPEH@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158535_k127_855414_0	525904.Tter_0415	1.377e-252	796.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158535_k127_855414_14	78346.BRUM_0658	2.963e-55	202.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158535_k127_855414_9	1047013.AQSP01000139_gene2394	2.135e-86	295.0	COG0501@1|root,COG0501@2|Bacteria,2NP1V@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
SRR25158535_k127_855414_42	1188256.BASI01000002_gene2976	2.077e-09	69.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,2U2JS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_855414_8	1068980.ARVW01000001_gene62	9.332e-91	323.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DYSZ@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	2.8.3.15,2.8.3.16,2.8.3.19	ko:K07544,ko:K07749,ko:K18702	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158535_k127_855454_0	469371.Tbis_2360	1.842e-225	708.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DXNT@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158535_k127_855454_2	1121451.DESAM_21420	2.797e-18	98.0	COG3852@1|root,COG5000@1|root,COG3852@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42Y7R@68525|delta/epsilon subdivisions,2WUCW@28221|Deltaproteobacteria,2MHJA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS
SRR25158535_k127_855454_1	1396141.BATP01000025_gene928	2.979e-62	223.0	COG0705@1|root,COG0705@2|Bacteria,46SYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158535_k127_883221_9	596328.HMPREF0578_0106	3.256e-14	73.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D67W@85005|Actinomycetales	201174|Actinobacteria	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158535_k127_883221_1	204669.Acid345_3196	1.527e-54	202.0	COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia	204432|Acidobacteriia	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
SRR25158535_k127_883221_0	1382306.JNIM01000001_gene721	4.611e-104	349.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1858,ParA
SRR25158535_k127_883221_13	195250.CM001776_gene3783	6.3e-05	54.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1G0TA@1117|Cyanobacteria,1GYQR@1129|Synechococcus	1117|Cyanobacteria	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2,TPR_19
SRR25158535_k127_883221_7	1123508.JH636452_gene6936	8.922e-19	100.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158535_k127_883221_6	1380390.JIAT01000009_gene2222	2.542e-21	108.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Polysacc_synt,Polysacc_synt_3
SRR25158535_k127_883221_5	1382306.JNIM01000001_gene689	5.929e-24	119.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158535_k127_883221_10	1348663.KCH_30750	7.847e-09	58.0	COG2835@1|root,COG2835@2|Bacteria,2I1H2@201174|Actinobacteria,2M3VG@2063|Kitasatospora	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158535_k127_883221_2	926569.ANT_08740	2.537e-51	198.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_883221_3	309801.trd_1599	6.767e-35	149.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,27XFQ@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
SRR25158535_k127_883221_4	110319.CF8_1196	4.376e-34	138.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DNS9@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_883221_11	446465.Bfae_25060	2.438e-08	68.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4FBXF@85020|Dermabacteraceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_883221_12	349521.HCH_05009	4.142e-05	57.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,1XIYX@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SRR25158535_k127_883221_8	1460635.JCM19038_4301	8.554e-18	97.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0005575,GO:0005623,GO:0030115,GO:0030312,GO:0044464,GO:0071944	2.7.11.1	ko:K12132,ko:K21471	-	-	-	-	ko00000,ko01000,ko01001,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158535_k127_932100_69	1449355.JQNR01000004_gene1435	1.124e-07	53.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM PfkB domain protein	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_932100_64	1192034.CAP_7284	4.861e-14	81.0	293AQ@1|root,2ZQTE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_36	867903.ThesuDRAFT_01076	1.442e-40	174.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WCG5@538999|Clostridiales incertae sedis	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_932100_59	314256.OG2516_00419	5.489e-17	95.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria,2PDAB@252301|Oceanicola	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15585	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_932100_27	479434.Sthe_1099	3.769e-71	265.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_932100_29	330214.NIDE3119	6.875e-65	241.0	COG0491@1|root,COG0491@2|Bacteria,3J1C9@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_932100_49	504728.K649_02050	2.199e-26	124.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	ypeA	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158535_k127_932100_39	1382304.JNIL01000001_gene1683	9.508e-36	149.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HKBA@91061|Bacilli,27A6B@186823|Alicyclobacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_932100_47	1120973.AQXL01000133_gene1703	7.012e-31	140.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,279BI@186823|Alicyclobacillaceae	91061|Bacilli	G	YjeF-related protein N-terminus	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158535_k127_932100_19	1128421.JAGA01000002_gene1791	1.788e-89	304.0	COG0345@1|root,COG0345@2|Bacteria,2NPIR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158535_k127_932100_61	761193.Runsl_5172	5.745e-16	91.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,47PDK@768503|Cytophagia	976|Bacteroidetes	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_932100_38	926560.KE387023_gene1505	1.095e-37	158.0	COG0613@1|root,COG0613@2|Bacteria,1WM4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158535_k127_932100_71	561175.KB894095_gene2176	3.125e-06	57.0	2ASGX@1|root,31HX4@2|Bacteria,2IFWG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_23	869210.Marky_2238	8.427e-81	279.0	COG1173@1|root,COG1173@2|Bacteria,1WJC3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_932100_13	479434.Sthe_0679	7.229e-108	358.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_932100_15	485913.Krac_3079	7.174e-101	348.0	COG0747@1|root,COG0747@2|Bacteria,2G6BC@200795|Chloroflexi	200795|Chloroflexi	E	COGs COG0747 ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_932100_67	477641.MODMU_0221	1.729e-08	68.0	2BYAG@1|root,2ZC13@2|Bacteria,2IGUZ@201174|Actinobacteria,4EW5H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_9	697284.ERIC2_c00860	1.396e-159	533.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,26QFD@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158535_k127_932100_8	1303518.CCALI_01905	3.243e-163	538.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_932100_65	415426.Hbut_0600	6.437e-11	73.0	arCOG00828@1|root,arCOG00828@2157|Archaea,2XS6C@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	FR47
SRR25158535_k127_932100_30	643648.Slip_0898	1.556e-64	229.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158535_k127_932100_50	518766.Rmar_0580	7.125e-26	121.0	COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,1FJ9S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Phosphoglycerate mutase family	gpm	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158535_k127_932100_51	671143.DAMO_2897	5.551e-25	115.0	COG5663@1|root,COG5663@2|Bacteria	2|Bacteria	S	phosphatase activity	yqfW	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158535_k127_932100_3	324602.Caur_3096	1.932e-260	841.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,375DR@32061|Chloroflexia	32061|Chloroflexia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158535_k127_932100_37	720554.Clocl_0324	4.707e-40	162.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158535_k127_932100_44	656024.FsymDg_0596	3.985e-33	141.0	COG1848@1|root,COG1848@2|Bacteria,2GUVQ@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_48	765420.OSCT_0224	9.691e-30	136.0	COG0642@1|root,COG2205@2|Bacteria,2G8TQ@200795|Chloroflexi,377EU@32061|Chloroflexia	32061|Chloroflexia	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
SRR25158535_k127_932100_20	670292.JH26_12610	5.776e-89	305.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2TV9C@28211|Alphaproteobacteria,1JW5R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158535_k127_932100_53	1333523.L593_10670	1.85e-24	115.0	COG0010@1|root,arCOG01700@2157|Archaea,2XU8D@28890|Euryarchaeota,23U2W@183963|Halobacteria	183963|Halobacteria	E	Belongs to the arginase family	arg1	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158535_k127_932100_5	357808.RoseRS_2983	1.931e-218	691.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,376YP@32061|Chloroflexia	32061|Chloroflexia	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158535_k127_932100_7	429009.Adeg_1889	6.639e-168	536.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,42F7G@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158535_k127_932100_0	292459.STH230	0.0	1331.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158535_k127_932100_73	1108045.GORHZ_046_00190	1.192e-05	52.0	COG2764@1|root,COG3324@1|root,COG2764@2|Bacteria,COG3324@2|Bacteria,2GMZD@201174|Actinobacteria,4GBPF@85026|Gordoniaceae	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_932100_74	366602.Caul_4637	0.0001198	51.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158535_k127_932100_68	1123065.ATWL01000005_gene1246	1.088e-07	56.0	2BSTJ@1|root,32MX0@2|Bacteria,2GY5J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_35	1171373.PACID_20270	2.044e-43	170.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DP53@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_932100_32	357808.RoseRS_4627	1.465e-45	184.0	COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi,374WN@32061|Chloroflexia	32061|Chloroflexia	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,HisKA_2
SRR25158535_k127_932100_16	357808.RoseRS_4617	8.858e-100	334.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,376NC@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_932100_40	1521187.JPIM01000068_gene745	7.212e-34	147.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_932100_17	1122603.ATVI01000005_gene3040	1.484e-96	329.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158535_k127_932100_62	696369.KI912183_gene104	1.262e-15	92.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
SRR25158535_k127_932100_14	1382356.JQMP01000003_gene1329	1.013e-102	365.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi,27XNG@189775|Thermomicrobia	189775|Thermomicrobia	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158535_k127_932100_18	663278.Ethha_1188	8.682e-95	328.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WHAN@541000|Ruminococcaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158535_k127_932100_41	383372.Rcas_4285	7.32e-34	138.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,375T7@32061|Chloroflexia	32061|Chloroflexia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158535_k127_932100_60	525904.Tter_1056	4.28e-16	80.0	COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S21	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158535_k127_932100_63	760568.Desku_1837	3.243e-15	84.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,261ZE@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158535_k127_932100_33	471852.Tcur_1904	3.177e-44	173.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4EFVW@85012|Streptosporangiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158535_k127_932100_54	1121472.AQWN01000002_gene2161	1.191e-22	113.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,260UN@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158535_k127_932100_31	479434.Sthe_1688	8.687e-54	200.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,27Y0Q@189775|Thermomicrobia	189775|Thermomicrobia	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158535_k127_932100_12	760568.Desku_2659	4.803e-115	382.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158535_k127_932100_2	525904.Tter_1750	9.273e-284	892.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158535_k127_932100_46	479434.Sthe_0715	9.651e-32	137.0	COG0576@1|root,COG0576@2|Bacteria,2G6WR@200795|Chloroflexi,27YDX@189775|Thermomicrobia	189775|Thermomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158535_k127_932100_26	383372.Rcas_4390	1.244e-71	255.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158535_k127_932100_43	1552123.EP57_07405	3.248e-33	136.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,26KNZ@186820|Listeriaceae	91061|Bacilli	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158535_k127_932100_52	195253.Syn6312_3364	1.72e-24	110.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1GZ8T@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_932100_34	1385521.N803_09835	2.027e-43	166.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4FFBU@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_932100_55	118168.MC7420_7636	3.651e-20	101.0	COG1476@1|root,COG1476@2|Bacteria,1G7B8@1117|Cyanobacteria	1117|Cyanobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158535_k127_932100_72	316067.Geob_2040	9.061e-06	58.0	COG0501@1|root,COG0501@2|Bacteria,1N5MJ@1224|Proteobacteria,43058@68525|delta/epsilon subdivisions,2WVHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_932100_42	886293.Sinac_1778	1.819e-33	147.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
SRR25158535_k127_932100_24	671143.DAMO_0479	4.368e-80	290.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR25158535_k127_932100_56	438753.AZC_4366	7.091e-20	98.0	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CHASE,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,dCache_1
SRR25158535_k127_932100_22	649831.L083_6799	3.181e-81	298.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4DAYW@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158535_k127_932100_28	1172188.KB911821_gene2078	2.159e-70	269.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158535_k127_932100_75	1298867.AUES01000015_gene3816	0.0006909	51.0	COG2197@1|root,COG2197@2|Bacteria,1RGH6@1224|Proteobacteria,2U81B@28211|Alphaproteobacteria,3JYXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_932100_57	937777.Deipe_3222	7.405e-20	101.0	COG3290@1|root,COG5000@1|root,COG3290@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	exsG	-	2.7.13.3,3.1.3.3	ko:K02476,ko:K03406,ko:K07315,ko:K07675,ko:K17763	ko02020,ko02030,map02020,map02030	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	GAF_2,GGDEF,HAMP,HATPase_c,HWE_HK,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,STAS,SpoIIE,dCache_1
SRR25158535_k127_932100_25	479434.Sthe_2394	1.386e-72	266.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi,27XYQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158535_k127_932100_4	479434.Sthe_1219	9.98e-254	795.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi,27XM4@189775|Thermomicrobia	189775|Thermomicrobia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158535_k127_932100_21	1449126.JQKL01000018_gene3286	1.434e-83	297.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,26BKG@186813|unclassified Clostridiales	186801|Clostridia	S	MviN-like protein	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158535_k127_932100_70	644966.Tmar_2193	1.244e-07	57.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158535_k127_932100_1	1131553.JIBI01000032_gene2300	0.0	1063.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,371SX@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Aconitase C-terminal domain	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158535_k127_932100_6	1123386.AUIW01000004_gene672	1.375e-174	574.0	COG0148@1|root,COG0148@2|Bacteria,1WIST@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158535_k127_932100_11	479434.Sthe_1252	9.453e-121	399.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,27XWV@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158535_k127_932100_10	526227.Mesil_2058	1.975e-126	409.0	COG0057@1|root,COG0057@2|Bacteria,1WIAD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158535_k127_94516_12	1128421.JAGA01000003_gene2767	3.84e-07	64.0	COG3538@1|root,COG3538@2|Bacteria	2|Bacteria	G	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRR25158535_k127_94516_1	1122222.AXWR01000058_gene265	6.825e-119	391.0	COG3842@1|root,COG3842@2|Bacteria,1WJ3G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158535_k127_94516_4	1128421.JAGA01000003_gene2769	1.742e-91	322.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158535_k127_94516_5	604331.AUHY01000061_gene1562	6.601e-87	296.0	COG1175@1|root,COG1175@2|Bacteria,1WJP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158535_k127_94516_0	1128421.JAGA01000003_gene2771	6.755e-142	463.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158535_k127_94516_8	1160137.KB907308_gene6811	2.842e-30	126.0	2ECJT@1|root,336HX@2|Bacteria,2IKEF@201174|Actinobacteria,4G4C3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_94516_6	1124780.ANNU01000037_gene134	6.77e-50	188.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,47XHT@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158535_k127_94516_9	234267.Acid_5276	1.433e-29	121.0	COG2764@1|root,COG2764@2|Bacteria,3Y4Z2@57723|Acidobacteria	57723|Acidobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_94516_2	1121423.JONT01000016_gene1162	1.513e-107	368.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25ZXV@186807|Peptococcaceae	186801|Clostridia	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
SRR25158535_k127_94516_11	1256908.HMPREF0373_00674	2.941e-07	62.0	COG3292@1|root,COG3292@2|Bacteria,1UICX@1239|Firmicutes,24ABD@186801|Clostridia	186801|Clostridia	T	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
SRR25158535_k127_94516_3	521098.Aaci_2221	5.572e-98	333.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158535_k127_94516_7	1297742.A176_04466	9.111e-31	140.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
SRR25158535_k127_94516_10	1273538.G159_04400	8.34e-16	81.0	COG4948@1|root,COG4948@2|Bacteria,1U140@1239|Firmicutes,4HAT9@91061|Bacilli	91061|Bacilli	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
SRR25158535_k127_956128_1	1003195.SCAT_2739	1.068e-172	561.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	ctpV	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K12956,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_956128_3	926560.KE387023_gene3326	1.062e-107	383.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
SRR25158535_k127_956128_0	1283299.AUKG01000001_gene3228	3.35e-197	629.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CP91@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158535_k127_956128_2	309801.trd_A0395	1.042e-120	408.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158535_k127_956128_8	314230.DSM3645_13293	2.417e-40	172.0	COG0348@1|root,COG3336@1|root,COG0348@2|Bacteria,COG3336@2|Bacteria,2J2XG@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRR25158535_k127_956128_6	1346791.M529_04540	3.223e-58	228.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U3G1@28211|Alphaproteobacteria,2K3ZD@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158535_k127_956128_17	309801.trd_0602	1.645e-11	75.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
SRR25158535_k127_956128_5	479434.Sthe_1582	2.838e-58	217.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158535_k127_956128_9	1002672.SAR11G3_00682	9.869e-38	149.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,4BP5G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158535_k127_956128_18	1211815.CBYP010000028_gene1057	6.712e-11	75.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4EVEN@85013|Frankiales	201174|Actinobacteria	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158535_k127_956128_14	1267534.KB906758_gene2124	4.164e-22	107.0	COG0697@1|root,COG0697@2|Bacteria,3Y4XS@57723|Acidobacteria,2JJHU@204432|Acidobacteriia	204432|Acidobacteriia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_956128_7	1128421.JAGA01000002_gene101	9.654e-41	173.0	COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria	2|Bacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158535_k127_956128_12	350054.Mflv_2816	1.028e-22	108.0	COG3682@1|root,COG3682@2|Bacteria,2IIIT@201174|Actinobacteria,23A3W@1762|Mycobacteriaceae	201174|Actinobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158535_k127_956128_16	1405.DJ92_4523	4.404e-19	99.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48,Peptidase_M56
SRR25158535_k127_956128_15	67267.JNXT01000002_gene6040	2.294e-19	102.0	COG1396@1|root,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8
SRR25158535_k127_956128_4	1121439.dsat_2289	6.961e-68	246.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2M9CM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_956128_19	494419.ALPM01000041_gene2611	5.876e-05	49.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR25158535_k127_956128_13	644966.Tmar_1104	1.156e-22	106.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158535_k127_956128_11	1142394.PSMK_27020	1.077e-29	134.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,Peptidase_M42
SRR25158535_k127_956128_10	357808.RoseRS_3331	4.188e-34	143.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,3759H@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.3.1.13	ko:K15526	-	-	-	-	ko00000,ko01000	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158535_k127_964511_0	867903.ThesuDRAFT_01433	7.657e-106	355.0	COG0446@1|root,COG0446@2|Bacteria,1TRNN@1239|Firmicutes,25EM2@186801|Clostridia	186801|Clostridia	P	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_964511_4	1122917.KB899659_gene5100	7.901e-06	55.0	COG2315@1|root,COG2315@2|Bacteria,1VYE4@1239|Firmicutes,4HXF5@91061|Bacilli	91061|Bacilli	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_964511_2	1120950.KB892742_gene3009	2.226e-17	86.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4DQY9@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_964511_1	1288079.AUKN01000006_gene3083	1.507e-48	190.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_964511_5	479434.Sthe_3486	1.983e-05	49.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_964511_3	1463825.JNXC01000001_gene6326	9.129e-12	78.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4E52D@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_979057_1	243231.GSU0780	1.138e-47	197.0	COG0746@1|root,COG1526@1|root,COG0746@2|Bacteria,COG1526@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2X5HH@28221|Deltaproteobacteria,43UTX@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,NTP_transf_3
SRR25158535_k127_979057_3	324602.Caur_3224	4.473e-23	106.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,375WZ@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_979057_2	485916.Dtox_3535	5.458e-36	154.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,249IS@186801|Clostridia,2655K@186807|Peptococcaceae	186801|Clostridia	O	PFAM Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD,Redoxin
SRR25158535_k127_979057_0	477641.MODMU_0856	5.178e-74	278.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
## 2440 queries scanned
## Total time (seconds): 5.893221855163574
## Rate: 414.03 q/s