## Sat Dec 13 15:09:43 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR21617310_bin.4.fa -m mmseqs --itype genome -o SRR21617310_bin.4 --output_dir /data/result/bins/wyx/egg/SRR21617310_bin.4 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR21617310_k127_1002155_5	358681.BBR47_13310	2.688e-72	262.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,26TUN@186822|Paenibacillaceae	91061|Bacilli	E	Allantoate amidohydrolase	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR21617310_k127_1002155_6	710111.FraQA3DRAFT_2660	3.546e-65	229.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR21617310_k127_1002155_7	1463821.JOGR01000009_gene1850	1.99e-45	172.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4F07N@85014|Glycomycetales	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_1002155_9	211114.JOEF01000022_gene5652	1.627e-10	66.0	COG0316@1|root,COG0316@2|Bacteria,2GR0Z@201174|Actinobacteria,4E7G9@85010|Pseudonocardiales	201174|Actinobacteria	S	HesB YadR YfhF-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR21617310_k127_1002155_0	390989.JOEG01000013_gene2562	3.996e-223	699.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR21617310_k127_1002155_3	1121020.JIAG01000001_gene1061	2.108e-160	517.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR21617310_k127_1002155_4	196162.Noca_4476	3.871e-95	324.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4DSTE@85009|Propionibacteriales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	3.7.1.19	ko:K06889,ko:K19188	ko00760,ko01120,map00760,map01120	M00810	R07515	RC00800,RC01921	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1100,Hydrolase_4
SRR21617310_k127_1002155_1	526225.Gobs_0795	9.383e-196	646.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4ESBD@85013|Frankiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR21617310_k127_1002155_2	1048339.KB913029_gene972	6.71e-178	560.0	COG0491@1|root,COG0491@2|Bacteria,2HTU1@201174|Actinobacteria,4EUGY@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_1002155_8	1449976.KALB_1637	4.446e-30	122.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4E0K4@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR21617310_k127_1003599_2	335543.Sfum_2106	1.506e-24	105.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,2MRHI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
SRR21617310_k127_1003599_0	1869.MB27_08225	1.099e-117	385.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4DD9W@85008|Micromonosporales	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_1003599_1	1449347.JQLN01000005_gene4068	3.075e-28	124.0	2EPBK@1|root,33GYC@2|Bacteria,2IHZ9@201174|Actinobacteria,2M5KC@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1012446_3	1136417.AZWE01000058_gene309	1.939e-105	349.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4DA6A@85008|Micromonosporales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_1012446_2	469383.Cwoe_0785	3.406e-126	414.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_1012446_1	1394178.AWOO02000081_gene2191	1.764e-138	451.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4EKR6@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR21617310_k127_1012446_4	1380391.JIAS01000020_gene1437	2.488e-88	306.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2JPPT@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR21617310_k127_1012446_10	1206744.BAGL01000032_gene3	1.282e-26	119.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4FZAK@85025|Nocardiaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	mdlC	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_1012446_11	797302.Halru_1801	8.292e-12	73.0	COG0028@1|root,arCOG03656@2157|Archaea,2XSZ0@28890|Euryarchaeota,23TRX@183963|Halobacteria	183963|Halobacteria	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_1012446_9	1382304.JNIL01000001_gene2406	9.617e-27	115.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli	91061|Bacilli	EH	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_1012446_8	1123325.JHUV01000001_gene97	4.728e-27	127.0	COG2171@1|root,COG2171@2|Bacteria,2G3KV@200783|Aquificae	200783|Aquificae	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR21617310_k127_1012446_7	1449126.JQKL01000009_gene343	2.385e-31	128.0	COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,24NN8@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR21617310_k127_1012446_6	477974.Daud_0613	1.329e-36	144.0	COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,24NN8@186801|Clostridia,262YW@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR21617310_k127_1012446_0	485913.Krac_0573	6.716e-144	469.0	COG0607@1|root,COG2059@1|root,COG0607@2|Bacteria,COG2059@2|Bacteria,2G6NB@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR21617310_k127_1012446_5	562970.Btus_0312	6.09e-49	184.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,278ZW@186823|Alicyclobacillaceae	91061|Bacilli	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_1017340_19	309801.trd_1837	1.004e-08	57.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi,27Z12@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR21617310_k127_1017340_11	298654.FraEuI1c_1812	9.292e-67	240.0	COG2129@1|root,COG2129@2|Bacteria,2GMTQ@201174|Actinobacteria,4ESW9@85013|Frankiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR21617310_k127_1017340_15	1121927.GOHSU_01_00270	8.65e-28	119.0	COG3427@1|root,COG3427@2|Bacteria,2I2PW@201174|Actinobacteria,4GGW5@85026|Gordoniaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR21617310_k127_1017340_3	42256.RradSPS_1289	6.374e-129	424.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4CPDY@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR21617310_k127_1017340_21	263358.VAB18032_27111	4.901e-05	49.0	2DSQS@1|root,33H36@2|Bacteria,2IJ17@201174|Actinobacteria,4DDNY@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1017340_16	309801.trd_0350	8.682e-21	105.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi,27XGI@189775|Thermomicrobia	189775|Thermomicrobia	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2
SRR21617310_k127_1017340_4	426716.JOAJ01000002_gene2056	5.359e-114	377.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4FZVS@85025|Nocardiaceae	201174|Actinobacteria	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR21617310_k127_1017340_17	1246995.AFR_23115	3.612e-13	81.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1017340_13	1382306.JNIM01000001_gene4082	7.516e-61	237.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
SRR21617310_k127_1017340_18	561175.KB894100_gene4819	1.837e-10	65.0	2E8UC@1|root,3334W@2|Bacteria,2GPHR@201174|Actinobacteria,4EK6N@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1017340_2	446470.Snas_4864	2.095e-151	492.0	COG1915@1|root,COG1915@2|Bacteria,2GMEZ@201174|Actinobacteria,4EY0H@85014|Glycomycetales	201174|Actinobacteria	S	LOR/SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR21617310_k127_1017340_5	1121946.AUAX01000052_gene8132	2.51e-95	323.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4DAY8@85008|Micromonosporales	201174|Actinobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR21617310_k127_1017340_8	1120949.KB903339_gene7772	9.805e-84	302.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DBH9@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_1017340_20	446466.Cfla_0215	2.086e-05	53.0	28RSK@1|root,2ZE50@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1017340_14	1095767.CAHD01000045_gene1379	2.928e-28	128.0	2C76P@1|root,32RIH@2|Bacteria,2IFWF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1017340_1	644283.Micau_5370	1.28e-214	683.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DACA@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_1017340_0	1120950.KB892773_gene1095	2.49e-236	774.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DPXV@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_1017340_10	1128421.JAGA01000001_gene2063	6.339e-72	254.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR21617310_k127_1017340_12	66429.JOFL01000013_gene2948	9.984e-65	233.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1017340_7	1121946.AUAX01000001_gene2517	1.882e-90	319.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4DBVQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SRR21617310_k127_1017340_6	1120948.KB903243_gene2684	4.063e-91	305.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E1D6@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1017340_9	1445613.JALM01000154_gene3696	2.728e-76	280.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4DZ84@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1018181_3	395495.Lcho_0314	2.738e-104	351.0	COG0807@1|root,COG0807@2|Bacteria,1MWUM@1224|Proteobacteria,2VJRX@28216|Betaproteobacteria,1KJRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Protein of unknown function (DUF1688)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1688
SRR21617310_k127_1018181_1	1144312.PMI09_04985	7.395e-128	450.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,SAM_1,SAM_2,TPR_12,TPR_4
SRR21617310_k127_1018181_2	227882.SAV_3641	1.102e-116	416.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR21617310_k127_1018181_4	1246474.ANBE01000024_gene1650	1.679e-82	286.0	COG2423@1|root,COG2423@2|Bacteria,2H4D8@201174|Actinobacteria,4EPZ7@85012|Streptosporangiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	ocd	-	1.5.1.51,4.3.1.12	ko:K01750,ko:K21721	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR21617310_k127_1018181_5	67281.JNZZ01000002_gene2873	7.789e-75	268.0	COG0031@1|root,COG0031@2|Bacteria,2GK6J@201174|Actinobacteria,41B5N@629295|Streptomyces griseus group	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
SRR21617310_k127_1018181_9	1246445.ANAY01000006_gene3871	0.0006108	48.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4EJRD@85012|Streptosporangiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR21617310_k127_1018181_0	1172188.KB911823_gene664	4.815e-207	653.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4FEHQ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR21617310_k127_1018181_6	68570.DC74_1156	9.281e-32	130.0	COG0596@1|root,COG0596@2|Bacteria,2GU04@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1018747_4	67257.JODR01000006_gene2672	4.307e-30	124.0	COG1371@1|root,COG1371@2|Bacteria,2IS0V@201174|Actinobacteria	201174|Actinobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR21617310_k127_1018747_3	1386089.N865_13070	1.648e-65	228.0	COG1839@1|root,COG1839@2|Bacteria,2IAR3@201174|Actinobacteria	201174|Actinobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
SRR21617310_k127_1018747_5	471852.Tcur_0705	1.247e-26	113.0	COG0517@1|root,COG0517@2|Bacteria,2I26I@201174|Actinobacteria,4EQHS@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_1018747_1	58123.JOFJ01000014_gene5035	5.417e-78	271.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1018747_7	1120949.KB903333_gene1478	0.0002197	47.0	COG0068@1|root,COG0298@1|root,COG0068@2|Bacteria,COG0298@2|Bacteria,2GJYF@201174|Actinobacteria,4DID7@85008|Micromonosporales	201174|Actinobacteria	O	Acylphosphatase	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR21617310_k127_1018747_2	997346.HMPREF9374_2301	6.777e-75	264.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,27BFI@186824|Thermoactinomycetaceae	91061|Bacilli	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR21617310_k127_1018747_6	882086.SacxiDRAFT_1886	1.738e-22	104.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4E2RM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR21617310_k127_1018747_0	391037.Sare_2646	1.302e-176	566.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4DIA2@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SRR21617310_k127_1024477_9	1299327.I546_2145	4.487e-11	65.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,238KA@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR21617310_k127_1024477_2	1463825.JNXC01000020_gene6629	2.225e-177	573.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZ8S@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin carboxylase	accBC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR21617310_k127_1024477_0	867845.KI911784_gene466	3.484e-235	753.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR21617310_k127_1024477_6	1087481.AGFX01000011_gene4123	7.757e-33	149.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR21617310_k127_1024477_7	1121430.JMLG01000001_gene2084	2.953e-22	109.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes,249A4@186801|Clostridia,260ZB@186807|Peptococcaceae	186801|Clostridia	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR21617310_k127_1024477_5	1313172.YM304_23350	4.253e-43	166.0	COG3428@1|root,COG3428@2|Bacteria,2HGDA@201174|Actinobacteria,4CNBH@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR21617310_k127_1024477_4	351607.Acel_0401	2.03e-91	310.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4ES54@85013|Frankiales	201174|Actinobacteria	E	PFAM Pyruvate carboxyltransferase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR21617310_k127_1024477_1	644966.Tmar_1390	7.517e-214	677.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,24BNG@186801|Clostridia,3WD5E@538999|Clostridiales incertae sedis	186801|Clostridia	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR21617310_k127_1024477_3	1108045.GORHZ_068_00060	1.468e-147	490.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4GA3N@85026|Gordoniaceae	201174|Actinobacteria	I	Biotin-lipoyl like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR21617310_k127_1024477_8	570268.ANBB01000043_gene1896	8.737e-17	88.0	COG2172@1|root,COG2172@2|Bacteria,2I1CW@201174|Actinobacteria,4EQMT@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR21617310_k127_1026905_2	1301098.PKB_3218	0.0009133	46.0	2EN2V@1|root,33FR1@2|Bacteria,1NJXZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1026905_0	68219.JNXI01000003_gene4907	6.517e-21	101.0	2EJ1U@1|root,33CT0@2|Bacteria,2GZFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1026905_1	1214242.B446_21120	1.657e-06	51.0	2CIKH@1|root,2ZMNN@2|Bacteria,2H042@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1027162_5	1128421.JAGA01000004_gene2704	5.06e-108	361.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR21617310_k127_1027162_1	1306990.BARG01000031_gene3536	7.012e-218	690.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR21617310_k127_1027162_4	309801.trd_A0452	4.111e-139	454.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR21617310_k127_1027162_0	649831.L083_6469	0.0	1477.0	COG3209@1|root,COG3209@2|Bacteria,2I35N@201174|Actinobacteria,4D8JW@85008|Micromonosporales	201174|Actinobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
SRR21617310_k127_1027162_2	653045.Strvi_3224	2.422e-198	653.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,TPR_7,Trans_reg_C
SRR21617310_k127_1027162_6	5127.CCT65373	3.535e-26	113.0	29BQI@1|root,2RITS@2759|Eukaryota,38NHV@33154|Opisthokonta,3PQE3@4751|Fungi,3R9WJ@4890|Ascomycota,21H9V@147550|Sordariomycetes,3TPRV@5125|Hypocreales,1FWW8@110618|Nectriaceae	4751|Fungi	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRR21617310_k127_1027162_3	1120797.KB908265_gene3909	4.113e-167	538.0	COG1167@1|root,COG1167@2|Bacteria,2GNFG@201174|Actinobacteria,237ND@1762|Mycobacteriaceae	201174|Actinobacteria	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,GntR
SRR21617310_k127_1035783_1	585531.HMPREF0063_11094	1.78e-45	179.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DNSR@85009|Propionibacteriales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR21617310_k127_1035783_0	446466.Cfla_2081	1.423e-202	645.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4F1WI@85016|Cellulomonadaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR21617310_k127_1035783_2	519442.Huta_0305	2.787e-43	166.0	COG1845@1|root,arCOG04650@2157|Archaea,2XTFU@28890|Euryarchaeota,23SSB@183963|Halobacteria	183963|Halobacteria	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR21617310_k127_1039888_1	512565.AMIS_34550	2.339e-118	389.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2ICGM@201174|Actinobacteria,4DDYE@85008|Micromonosporales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR21617310_k127_1039888_2	263358.VAB18032_15560	0.0001101	52.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_1039888_0	345341.KUTG_08460	1.775e-195	626.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_1039901_5	246194.CHY_1492	9.628e-108	356.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42ERE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_1039901_6	370438.PTH_1800	3.174e-77	278.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR21617310_k127_1039901_7	1246995.AFR_35555	4.377e-73	259.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4D8F0@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR21617310_k127_1039901_8	1380346.JNIH01000015_gene577	2.42e-30	136.0	COG3885@1|root,COG3885@2|Bacteria,2GN3T@201174|Actinobacteria	201174|Actinobacteria	S	ferrous iron binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1039901_1	471857.Svir_27690	3.308e-172	558.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DXJ9@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR21617310_k127_1039901_0	469371.Tbis_1120	7.046e-178	574.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria	201174|Actinobacteria	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR21617310_k127_1039901_11	1386089.N865_17235	3.057e-19	97.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4FGQS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR21617310_k127_1039901_2	397278.JOJN01000007_gene3407	1.729e-168	537.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4DPDK@85009|Propionibacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR21617310_k127_1039901_10	290397.Adeh_3960	5.653e-20	100.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR21617310_k127_1039901_3	106370.Francci3_3538	8.216e-119	394.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR21617310_k127_1039901_4	1123320.KB889675_gene3987	8.597e-117	392.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR21617310_k127_1039901_9	1121468.AUBR01000009_gene2167	7.768e-30	128.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR21617310_k127_1049157_5	1394178.AWOO02000076_gene1941	4.75e-33	132.0	COG0789@1|root,COG0789@2|Bacteria,2I8T8@201174|Actinobacteria,4EFXZ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR21617310_k127_1049157_1	28444.JODQ01000002_gene3954	1.542e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,2INGP@201174|Actinobacteria,4EJR9@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_1049157_6	697281.Mahau_1854	8.637e-21	99.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42GMG@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR21617310_k127_1049157_4	1110697.NCAST_18_00730	2.888e-39	168.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,4FXUG@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glycos_transf_2
SRR21617310_k127_1049157_0	443906.CMM_2884	2.07e-58	227.0	COG0382@1|root,COG0382@2|Bacteria,2GKJ2@201174|Actinobacteria,4FKV3@85023|Microbacteriaceae	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	ko:K20616	-	-	-	-	ko00000	-	-	-	UbiA
SRR21617310_k127_1049157_7	1449058.JQKT01000007_gene1030	7.515e-09	61.0	COG3266@1|root,COG3266@2|Bacteria,2GQFT@201174|Actinobacteria,4FQ7G@85023|Microbacteriaceae	201174|Actinobacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1049157_3	1128421.JAGA01000003_gene3733	9.214e-42	164.0	COG1404@1|root,COG1404@2|Bacteria,2NRPB@2323|unclassified Bacteria	2|Bacteria	O	Domain of unknown function (DUF4397)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
SRR21617310_k127_1049157_2	1380356.JNIK01000016_gene3716	2.689e-46	174.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4ET12@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR21617310_k127_1049157_8	345341.KUTG_05605	9.193e-09	62.0	COG1595@1|root,COG1595@2|Bacteria,2GUGU@201174|Actinobacteria,4E8EB@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1050127_3	1121924.ATWH01000004_gene2235	3.874e-82	280.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4FK8F@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	sugC	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR21617310_k127_1050127_2	1121924.ATWH01000004_gene2236	3.577e-104	350.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4FKP3@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	sugD	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR21617310_k127_1050127_1	351607.Acel_0758	1.846e-121	405.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4ES3D@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR21617310_k127_1050127_4	471852.Tcur_1548	2.695e-31	124.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4EJZP@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR21617310_k127_1050127_5	1463825.JNXC01000002_gene4803	5.964e-23	104.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4E4K1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR21617310_k127_1050127_0	298655.KI912266_gene5495	1.424e-163	533.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4ERY4@85013|Frankiales	201174|Actinobacteria	J	ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR21617310_k127_1050235_3	479433.Caci_3065	1.068e-38	167.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR21617310_k127_1050235_1	525904.Tter_2548	9.147e-63	224.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,HATPase_c,HisKA_3,Response_reg
SRR21617310_k127_1050235_2	479434.Sthe_0156	1.905e-54	210.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR21617310_k127_1050235_0	714943.Mucpa_7156	1.954e-68	260.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR21617310_k127_1050235_4	1324957.K933_00687	1.216e-36	154.0	COG2244@1|root,arCOG02209@2157|Archaea,2XUGQ@28890|Euryarchaeota,23SS6@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR21617310_k127_1050986_1	1120950.KB892810_gene7212	1.047e-140	454.0	COG1718@1|root,COG1718@2|Bacteria,2GM3J@201174|Actinobacteria,4DQ46@85009|Propionibacteriales	201174|Actinobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
SRR21617310_k127_1050986_4	1246995.AFR_37610	2.373e-39	159.0	COG4319@1|root,COG4319@2|Bacteria,2IRHC@201174|Actinobacteria,4DFA7@85008|Micromonosporales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_1050986_3	103733.JNYO01000007_gene5144	1.506e-45	169.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4E4E6@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1050986_2	2074.JNYD01000006_gene1756	4.178e-131	421.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DZFT@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR21617310_k127_1050986_0	994479.GL877878_gene1408	3.166e-228	735.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4DZZ5@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_1050986_5	408672.NBCG_01696	2.812e-12	73.0	COG1247@1|root,COG1247@2|Bacteria,2IMVR@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_1052735_2	1242864.D187_002220	8.418e-06	55.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2YXU5@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR21617310_k127_1052735_1	1463917.JODC01000010_gene4209	3.198e-50	185.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR21617310_k127_1052735_0	1382306.JNIM01000001_gene3284	0.0	1399.0	COG3387@1|root,COG4945@1|root,COG3387@2|Bacteria,COG4945@2|Bacteria,2G69A@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase 15-related	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_C,Glucodextran_N,Glyco_hydro_15
SRR21617310_k127_1052882_15	644283.Micau_4791	1.069e-13	71.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DAC4@85008|Micromonosporales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR21617310_k127_1052882_4	1380390.JIAT01000015_gene5878	2.402e-71	258.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR21617310_k127_1052882_8	1089544.KB912942_gene1470	2.291e-35	139.0	arCOG03092@1|root,32YMQ@2|Bacteria,2I3JS@201174|Actinobacteria,4E63Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR21617310_k127_1052882_7	479432.Sros_6856	2.772e-56	215.0	COG2214@1|root,COG2214@2|Bacteria,2I34A@201174|Actinobacteria,4EITC@85012|Streptosporangiales	201174|Actinobacteria	O	Gas vesicle synthesis protein GvpL/GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR21617310_k127_1052882_14	2074.JNYD01000013_gene6793	1.444e-14	79.0	2EJC3@1|root,33D37@2|Bacteria,2GQN8@201174|Actinobacteria,4E7UP@85010|Pseudonocardiales	201174|Actinobacteria	S	Gas vesicle protein G	-	-	-	-	-	-	-	-	-	-	-	-	GvpG
SRR21617310_k127_1052882_11	1343740.M271_07230	3.807e-24	107.0	arCOG04040@1|root,334QT@2|Bacteria,2GQNG@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicle	gvpO	-	-	-	-	-	-	-	-	-	-	-	GvpO
SRR21617310_k127_1052882_10	653045.Strvi_3655	8.439e-35	138.0	2E5BC@1|root,3303G@2|Bacteria,2IR3J@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR21617310_k127_1052882_6	479432.Sros_6860	6.933e-62	224.0	297MT@1|root,2ZUUR@2|Bacteria,2I3JT@201174|Actinobacteria,4EIY3@85012|Streptosporangiales	201174|Actinobacteria	S	Gas vesicle synthesis protein GvpL/GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR21617310_k127_1052882_16	882086.SacxiDRAFT_0166	9.422e-13	74.0	2DRDP@1|root,33BB6@2|Bacteria,2GQXX@201174|Actinobacteria,4E7PV@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Gas vesicle protein	gvpS1	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR21617310_k127_1052882_9	1206733.BAGC01000099_gene6185	3.786e-35	138.0	arCOG06390@1|root,330IR@2|Bacteria,2IQAU@201174|Actinobacteria,4G2BR@85025|Nocardiaceae	201174|Actinobacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	GvpK
SRR21617310_k127_1052882_12	390989.JOEG01000017_gene6156	3.573e-17	93.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4DG4K@85008|Micromonosporales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR21617310_k127_1052882_0	292415.Tbd_1072	0.0	1030.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
SRR21617310_k127_1052882_2	2002.JOEQ01000049_gene2250	1.731e-185	585.0	COG1980@1|root,COG1980@2|Bacteria,2IDT3@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
SRR21617310_k127_1052882_3	42256.RradSPS_3058	3.122e-103	348.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1052882_5	557599.MKAN_19010	6.233e-63	227.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,236GW@1762|Mycobacteriaceae	201174|Actinobacteria	J	Ribosome-associated protein Y (PSrp-1)	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR21617310_k127_1052882_13	1128421.JAGA01000003_gene2823	1.933e-16	85.0	COG2606@1|root,COG2606@2|Bacteria,2NPZ1@2323|unclassified Bacteria	2|Bacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR21617310_k127_1052882_1	298655.KI912266_gene5057	1.048e-219	697.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_1058635_0	1121272.KB903293_gene7158	9.166e-15	87.0	2A152@1|root,30PAX@2|Bacteria,2IGUI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1058635_2	1408324.JNJK01000010_gene2116	4.605e-07	59.0	COG1216@1|root,COG1216@2|Bacteria,1VWEX@1239|Firmicutes,2516B@186801|Clostridia,27PDA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF616,Glyco_tranf_2_5
SRR21617310_k127_1061548_2	1380386.JIAW01000030_gene3588	5.72e-177	563.0	2DWN2@1|root,3414B@2|Bacteria,2IC7M@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1061548_0	1380386.JIAW01000030_gene3597	4.318e-236	735.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria,23496@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR21617310_k127_1061548_11	492774.JQMB01000002_gene773	3.512e-23	106.0	2AAE0@1|root,30ZQ8@2|Bacteria,1PMNU@1224|Proteobacteria,2V08Z@28211|Alphaproteobacteria,4BJFF@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1061548_5	1231391.AMZF01000094_gene101	3.403e-129	421.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria	1224|Proteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR21617310_k127_1061548_6	1463857.JOFZ01000005_gene3347	5.583e-127	414.0	COG0596@1|root,COG0596@2|Bacteria,2IAKH@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_1061548_10	1380386.JIAW01000030_gene3576	1.036e-55	199.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR21617310_k127_1061548_7	1463857.JOFZ01000005_gene3344	2.902e-120	421.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR21617310_k127_1061548_1	1463857.JOFZ01000005_gene3343	5.447e-191	623.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_1061548_8	1120949.KB903294_gene4222	1.561e-96	321.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4DCVQ@85008|Micromonosporales	201174|Actinobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR21617310_k127_1061548_3	1440774.Y900_028855	2.488e-162	522.0	COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria,238F9@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR21617310_k127_1061548_4	1449353.JQMQ01000005_gene5573	1.601e-151	485.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR21617310_k127_1061548_12	543632.JOJL01000017_gene9893	8.37e-20	93.0	COG1309@1|root,COG1309@2|Bacteria,2GPI5@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1064103_3	1169161.KB897750_gene2701	3.153e-98	325.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR21617310_k127_1064103_15	397278.JOJN01000001_gene2725	4.198e-33	130.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR21617310_k127_1064103_10	477974.Daud_2224	4.496e-49	183.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR21617310_k127_1064103_5	391625.PPSIR1_25986	2.546e-84	300.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR21617310_k127_1064103_9	1123023.JIAI01000006_gene207	5.822e-59	218.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DY1U@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR21617310_k127_1064103_4	29306.JOBE01000006_gene4403	2.842e-94	323.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR21617310_k127_1064103_17	324057.Pjdr2_1014	3.941e-23	108.0	2CKD9@1|root,333BQ@2|Bacteria,1VIGZ@1239|Firmicutes,4HQNF@91061|Bacilli,26RC6@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1064103_18	953739.SVEN_5257	5.898e-23	101.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR21617310_k127_1064103_0	292459.STH1384	2.348e-176	595.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR21617310_k127_1064103_20	1463856.JOHY01000019_gene2587	8.716e-18	96.0	COG1378@1|root,COG1378@2|Bacteria,2IB4E@201174|Actinobacteria	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
SRR21617310_k127_1064103_22	1114856.C496_02075	2.205e-08	65.0	COG1378@1|root,arCOG02037@2157|Archaea,2XV7W@28890|Euryarchaeota,23TEQ@183963|Halobacteria	183963|Halobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
SRR21617310_k127_1064103_14	1380356.JNIK01000011_gene1773	7.219e-37	148.0	COG3795@1|root,COG3795@2|Bacteria,2GT1V@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_1064103_1	469383.Cwoe_2508	7.148e-168	542.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4CS3T@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1064103_13	1223543.GP2_001_01100	1.287e-39	154.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4GDSX@85026|Gordoniaceae	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR21617310_k127_1064103_8	1114959.SZMC14600_11073	8.65e-63	219.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4E33S@85010|Pseudonocardiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR21617310_k127_1064103_16	106370.Francci3_3604	6.921e-28	127.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4ESTS@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR21617310_k127_1064103_21	1122182.KB903833_gene5354	3.199e-14	79.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4DFJS@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR21617310_k127_1064103_6	269800.Tfu_0651	2.295e-81	280.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4EGGX@85012|Streptosporangiales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR21617310_k127_1064103_7	1288079.AUKN01000002_gene5520	1.519e-67	239.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR21617310_k127_1064103_11	370438.PTH_1977	9.807e-45	173.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR21617310_k127_1064103_12	469383.Cwoe_4333	7.081e-44	171.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria	201174|Actinobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR21617310_k127_1064103_19	511051.CSE_07860	1.678e-21	96.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
SRR21617310_k127_1064103_2	469371.Tbis_2776	4.306e-131	446.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DYMX@85010|Pseudonocardiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR21617310_k127_1065997_1	314278.NB231_04685	3.788e-161	520.0	COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,1X2PW@135613|Chromatiales	135613|Chromatiales	S	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR21617310_k127_1065997_4	518766.Rmar_2587	1.428e-37	145.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
SRR21617310_k127_1065997_3	518766.Rmar_2588	6.103e-108	357.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR21617310_k127_1065997_2	2002.JOEQ01000013_gene5456	8.075e-127	413.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria,4EIDA@85012|Streptosporangiales	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SRR21617310_k127_1065997_0	58123.JOFJ01000014_gene5030	8.351e-191	612.0	COG3259@1|root,COG3259@2|Bacteria,2GQ33@201174|Actinobacteria,4EGG1@85012|Streptosporangiales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRR21617310_k127_1065997_5	35754.JNYJ01000042_gene1372	6.307e-23	115.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR21617310_k127_1065997_6	106370.Francci3_3407	8.793e-16	80.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,4EVI4@85013|Frankiales	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR21617310_k127_1068456_2	1206725.BAFU01000058_gene853	0.0001582	52.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4FX3Z@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	tnpAC	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_1068456_1	1449353.JQMQ01000005_gene4562	2.633e-18	92.0	COG0662@1|root,COG0662@2|Bacteria,2I5KR@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1068456_0	1123023.JIAI01000001_gene6028	1.419e-82	276.0	COG3871@1|root,COG3871@2|Bacteria,2I3KD@201174|Actinobacteria,4E3CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1071716_3	1120949.KB903294_gene3869	1.077e-108	361.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4DAJM@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR21617310_k127_1071716_1	1120936.KB907208_gene698	1.12e-129	424.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4EFH6@85012|Streptosporangiales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR21617310_k127_1071716_4	1120950.KB892804_gene1468	1.23e-107	361.0	COG2222@1|root,COG2222@2|Bacteria,2I433@201174|Actinobacteria,4DR3Q@85009|Propionibacteriales	201174|Actinobacteria	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR21617310_k127_1071716_0	477641.MODMU_4875	1.15e-140	467.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4ERSE@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR21617310_k127_1071716_8	1380347.JNII01000010_gene2416	7.019e-47	173.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4ESQW@85013|Frankiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR21617310_k127_1071716_6	351607.Acel_0341	1.135e-62	219.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4ESPF@85013|Frankiales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR21617310_k127_1071716_5	65497.JODV01000007_gene443	3.372e-65	231.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DZVD@85010|Pseudonocardiales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR21617310_k127_1071716_7	526225.Gobs_4478	1.101e-49	193.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR21617310_k127_1071716_2	164757.Mjls_1142	4.345e-125	407.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,2350J@1762|Mycobacteriaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR21617310_k127_1073449_6	1944.JOAZ01000038_gene5731	1.784e-34	154.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_1073449_14	591158.SSMG_01875	1.272e-08	67.0	COG1396@1|root,COG1396@2|Bacteria,2GN9P@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1073449_11	882083.SacmaDRAFT_4190	1.46e-17	96.0	COG0457@1|root,COG0457@2|Bacteria,2I5R1@201174|Actinobacteria,4EE7V@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1073449_13	1394178.AWOO02000003_gene2563	1.318e-11	67.0	COG3311@1|root,COG3311@2|Bacteria,2I21C@201174|Actinobacteria,4EQA7@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_1073449_8	1907.SGLAU_33060	2.065e-29	120.0	2EF5E@1|root,31KM2@2|Bacteria,2IKZ8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1073449_9	1229780.BN381_130135	3.883e-27	113.0	COG2002@1|root,COG2002@2|Bacteria,2GUD2@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR21617310_k127_1073449_15	1121022.ABENE_22850	0.0003108	48.0	2DFTW@1|root,2ZT49@2|Bacteria,1NI21@1224|Proteobacteria	1224|Proteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_1073449_2	1394178.AWOO02000003_gene2564	3.154e-100	336.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ENZ4@85012|Streptosporangiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_1073449_3	1370120.AUWR01000058_gene2445	2.654e-81	276.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,235VU@1762|Mycobacteriaceae	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR21617310_k127_1073449_0	1121877.JQKF01000007_gene967	1.308e-275	864.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR21617310_k127_1073449_10	869210.Marky_0753	3.646e-23	106.0	COG1430@1|root,COG1430@2|Bacteria,1WJRZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR21617310_k127_1073449_5	1122138.AQUZ01000031_gene4219	1.426e-52	188.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4DP1V@85009|Propionibacteriales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR21617310_k127_1073449_1	68570.DC74_7713	7.61e-216	680.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR21617310_k127_1073449_7	1487923.DP73_12035	5.899e-34	146.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR21617310_k127_1073449_4	1050202.KB913024_gene3533	8.781e-70	242.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,407VJ@622450|Actinopolysporales	201174|Actinobacteria	O	DnaJ central domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR21617310_k127_1074538_4	1463879.JOHP01000005_gene6038	9.134e-08	62.0	2DKWW@1|root,30NAT@2|Bacteria,2GKYJ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR21617310_k127_1074538_0	656024.FsymDg_3294	0.0	1400.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4ETR9@85013|Frankiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR21617310_k127_1074538_2	1089545.KB913037_gene7111	6.754e-22	104.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4E8AR@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1074538_3	1048339.KB913029_gene482	1.784e-12	69.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4ERUB@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1074538_1	1089545.KB913037_gene7111	1.403e-81	279.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4E8AR@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1079946_1	1136417.AZWE01000066_gene1147	2.585e-113	377.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D9V4@85008|Micromonosporales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1079946_5	2002.JOEQ01000004_gene2890	1.132e-12	72.0	COG0790@1|root,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria,4EI5V@85012|Streptosporangiales	201174|Actinobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
SRR21617310_k127_1079946_0	1380390.JIAT01000010_gene4381	2.576e-235	731.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4CS3C@84995|Rubrobacteria	84995|Rubrobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR21617310_k127_1079946_4	936455.KI421499_gene3128	1.297e-16	81.0	COG0142@1|root,COG0142@2|Bacteria,1PACF@1224|Proteobacteria	1224|Proteobacteria	H	geranyltranstransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1079946_7	1206741.BAFX01000017_gene7101	5.472e-09	61.0	COG0142@1|root,COG0142@2|Bacteria,2IGFE@201174|Actinobacteria,4G1WX@85025|Nocardiaceae	201174|Actinobacteria	H	geranyltranstransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1079946_9	999541.bgla_1g07700	3.723e-05	46.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2VM0R@28216|Betaproteobacteria,1JZY1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR21617310_k127_1079946_3	717606.PaecuDRAFT_2611	4.246e-18	98.0	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,26TGK@186822|Paenibacillaceae	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1079946_6	1206725.BAFU01000219_gene11	9.068e-10	67.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_1079946_8	1246448.ANAZ01000018_gene243	1.508e-05	51.0	COG3415@1|root,COG3415@2|Bacteria,2IHIM@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_29,HTH_32,HTH_33
SRR21617310_k127_1079946_2	1463921.JODF01000005_gene6237	1.444e-64	222.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR21617310_k127_1080005_12	1184607.AUCHE_18_00960	4.278e-20	99.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4F6HN@85018|Dermatophilaceae	201174|Actinobacteria	T	Protein phosphatase 2C	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR21617310_k127_1080005_3	1123251.ATWM01000002_gene237	3.32e-146	467.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4FF7F@85021|Intrasporangiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR21617310_k127_1080005_8	42256.RradSPS_1141	3.368e-50	193.0	COG2166@1|root,COG2166@2|Bacteria,2IMBF@201174|Actinobacteria	201174|Actinobacteria	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRR21617310_k127_1080005_15	1380390.JIAT01000009_gene1531	1.817e-05	49.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_1080005_9	1449048.JQKU01000022_gene2768	4.075e-44	168.0	COG1309@1|root,COG1309@2|Bacteria,2GNMP@201174|Actinobacteria,232XT@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1080005_2	909613.UO65_1558	6.665e-170	544.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria,4EAZS@85010|Pseudonocardiales	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR21617310_k127_1080005_5	284031.JNXD01000009_gene2045	2.216e-116	394.0	COG1073@1|root,COG1073@2|Bacteria,2I2V0@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR21617310_k127_1080005_10	1283283.ATXA01000021_gene2880	4.102e-44	185.0	COG0258@1|root,COG0258@2|Bacteria,2I4UY@201174|Actinobacteria	201174|Actinobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR21617310_k127_1080005_1	298654.FraEuI1c_0666	7.269e-234	731.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4ES5K@85013|Frankiales	201174|Actinobacteria	H	Mg-chelatase subunit ChlI	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR21617310_k127_1080005_0	471852.Tcur_1053	1.181e-256	823.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4EG1M@85012|Streptosporangiales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR21617310_k127_1080005_7	656024.FsymDg_1808	4.447e-57	205.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4ESXH@85013|Frankiales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR21617310_k127_1080005_4	675635.Psed_6012	4.761e-126	417.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4EAJ0@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K10907,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_1080005_6	1121428.DESHY_60276___1	1.781e-65	230.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,261IS@186807|Peptococcaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR21617310_k127_1080005_13	326423.RBAM_003830	2.823e-16	86.0	2DAI9@1|root,32TVI@2|Bacteria,1VD47@1239|Firmicutes,4HKCX@91061|Bacilli,1ZIAY@1386|Bacillus	91061|Bacilli	-	-	yclD	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1080005_11	1125863.JAFN01000001_gene1355	1.375e-35	143.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR21617310_k127_1084245_2	1463885.KL578487_gene8521	1.602e-08	57.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_1084245_0	469383.Cwoe_1926	2.801e-148	486.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1084245_1	1146883.BLASA_2115	2.733e-73	261.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4ES95@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR21617310_k127_1084252_0	469371.Tbis_1261	5.77e-157	517.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4DZJZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR21617310_k127_1084252_2	460265.Mnod_1045	8.044e-59	216.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,1JTP6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR21617310_k127_1084252_6	1120949.KB903294_gene4051	8.262e-08	57.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_1084252_1	469383.Cwoe_1926	5.176e-77	274.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1084252_3	2074.JNYD01000001_gene5850	8.105e-20	95.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4E26T@85010|Pseudonocardiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1084252_4	1515746.HR45_11500	1.338e-10	70.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria,2Q9KM@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4,Laminin_G_3
SRR21617310_k127_1084252_5	1463885.KL578487_gene8521	1.602e-08	57.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_1089088_4	1123024.AUII01000006_gene4635	5.461e-71	254.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1089088_0	1077972.ARGLB_047_00920	0.0	1350.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,1WCG2@1268|Micrococcaceae	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR21617310_k127_1089088_7	1150398.JIBJ01000004_gene2790	3.472e-23	105.0	COG0845@1|root,COG0845@2|Bacteria,2I53W@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1089088_1	1077972.ARGLB_047_00920	2e-322	1019.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,1WCG2@1268|Micrococcaceae	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR21617310_k127_1089088_5	1463936.JOJI01000025_gene1449	1.304e-67	246.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_1089088_3	1463920.JOGB01000002_gene3215	1.121e-85	288.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1089088_2	196367.JNFG01000016_gene4044	3.485e-124	407.0	COG0500@1|root,COG2226@2|Bacteria,1PECT@1224|Proteobacteria,2VYBR@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_1089088_6	298654.FraEuI1c_6099	1.459e-46	188.0	COG1807@1|root,COG1807@2|Bacteria,2H1H7@201174|Actinobacteria,4EW4Y@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1092532_2	234267.Acid_1198	9.987e-175	565.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_1092532_4	298653.Franean1_3436	6.066e-22	102.0	COG1321@1|root,COG1321@2|Bacteria,2ICG2@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1092532_0	37919.EP51_00880	1.851e-271	848.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4FUY0@85025|Nocardiaceae	201174|Actinobacteria	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_1092532_6	306281.AJLK01000177_gene2471	8.328e-05	46.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	Intron_maturas2,RVT_1
SRR21617310_k127_1092532_1	298653.Franean1_3436	2.743e-250	780.0	COG1321@1|root,COG1321@2|Bacteria,2ICG2@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1092532_3	675635.Psed_0049	8.49e-89	299.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4E1YI@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_1098455_2	196162.Noca_1531	9.507e-30	126.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	mdtH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06610,ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.1.27,2.A.1.2.21	-	-	MFS_1,Sugar_tr
SRR21617310_k127_1098455_3	1463887.KL590056_gene7488	6.312e-15	75.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR21617310_k127_1098455_4	882086.SacxiDRAFT_0020	3.583e-07	63.0	2DY1Q@1|root,347NS@2|Bacteria,2GTP5@201174|Actinobacteria,4E6NG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1098455_1	656024.FsymDg_1161	1.682e-34	152.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4ETXP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR21617310_k127_1098455_0	1463900.JOIX01000001_gene6304	1.265e-43	162.0	COG0477@1|root,COG2814@2|Bacteria,2HRV9@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1107471_0	1206731.BAGB01000013_gene2257	5.011e-30	132.0	COG5632@1|root,COG5632@2|Bacteria,2I2P5@201174|Actinobacteria,4G9V8@85025|Nocardiaceae	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DUF1906
SRR21617310_k127_1107471_3	526227.Mesil_3332	9.716e-16	85.0	2CMWR@1|root,32SFR@2|Bacteria,1WMJ5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1107471_1	953739.SVEN_2147	8.876e-30	126.0	2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria	201174|Actinobacteria	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
SRR21617310_k127_1107471_2	68219.JNXI01000003_gene4907	2.263e-27	114.0	2EJ1U@1|root,33CT0@2|Bacteria,2GZFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1108133_11	1476876.JOJO01000050_gene8093	2.744e-42	160.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR21617310_k127_1108133_6	105422.BBPM01000019_gene2571	6.823e-92	313.0	COG1277@1|root,COG1277@2|Bacteria,2GJ2R@201174|Actinobacteria,2NI70@228398|Streptacidiphilus	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR21617310_k127_1108133_4	134676.ACPL_8000	2.242e-119	388.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DCC0@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1108133_13	1209984.BN978_02420	2.145e-21	106.0	COG1266@1|root,COG1266@2|Bacteria,2GK11@201174|Actinobacteria,232IP@1762|Mycobacteriaceae	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR21617310_k127_1108133_5	526225.Gobs_3431	1.558e-113	387.0	COG2223@1|root,COG2223@2|Bacteria,2I4JW@201174|Actinobacteria	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR21617310_k127_1108133_9	67267.JNXT01000047_gene7727	2.162e-55	202.0	COG2186@1|root,COG2186@2|Bacteria,2GMTJ@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_1108133_10	479435.Kfla_4624	1.028e-49	199.0	COG0500@1|root,COG2226@2|Bacteria,2II6W@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR21617310_k127_1108133_3	211114.JOEF01000037_gene6876	7.685e-130	425.0	COG0715@1|root,COG0715@2|Bacteria,2I95I@201174|Actinobacteria,4E1JF@85010|Pseudonocardiales	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1108133_7	1449976.KALB_3985	5.59e-81	278.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4E28F@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR21617310_k127_1108133_12	1449355.JQNR01000005_gene4591	3.426e-28	118.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_1108133_2	1380390.JIAT01000010_gene4969	8.71e-144	462.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR21617310_k127_1108133_0	526225.Gobs_3367	0.0	1317.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4ERFA@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR21617310_k127_1108133_1	219305.MCAG_04576	4.228e-236	755.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4D8VX@85008|Micromonosporales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
SRR21617310_k127_1108133_8	1206744.BAGL01000064_gene4428	5.412e-77	271.0	COG0604@1|root,COG0604@2|Bacteria,2I8KK@201174|Actinobacteria,4G2WU@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_1118901_17	1121378.KB899703_gene2288	1.662e-54	211.0	COG2244@1|root,COG2244@2|Bacteria,1WMMR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3
SRR21617310_k127_1118901_13	1173027.Mic7113_2164	1.024e-76	267.0	COG1216@1|root,COG1216@2|Bacteria,1G10I@1117|Cyanobacteria,1H8DQ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR21617310_k127_1118901_15	298655.KI912266_gene1240	1.542e-61	233.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria	201174|Actinobacteria	DM	biosynthesis protein	-	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,Wzz
SRR21617310_k127_1118901_8	1232410.KI421421_gene3375	9.611e-122	410.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,43AVS@68525|delta/epsilon subdivisions,2X69U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
SRR21617310_k127_1118901_6	479434.Sthe_3442	9.466e-136	464.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,27XSM@189775|Thermomicrobia	2|Bacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR21617310_k127_1118901_11	1121926.AXWO01000031_gene2431	4.478e-101	343.0	COG1922@1|root,COG1922@2|Bacteria,2ICDG@201174|Actinobacteria,4EYRY@85014|Glycomycetales	201174|Actinobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	rffM	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR21617310_k127_1118901_14	106370.Francci3_3854	1.288e-64	243.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4ES81@85013|Frankiales	201174|Actinobacteria	M	PFAM sugar transferase	rfbP	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR21617310_k127_1118901_22	1171373.PACID_06190	4.605e-10	66.0	COG4758@1|root,COG4758@2|Bacteria,2I7RZ@201174|Actinobacteria,4DWIR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR21617310_k127_1118901_12	1120950.KB892708_gene4370	3.584e-83	284.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria,4DT8G@85009|Propionibacteriales	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR21617310_k127_1118901_1	675635.Psed_1052	1.635e-170	542.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DY7I@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	sugC	GO:0006810,GO:0008150,GO:0008643,GO:0009405,GO:0015766,GO:0015771,GO:0015772,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0071702	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR21617310_k127_1118901_7	298654.FraEuI1c_4049	2.619e-126	417.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4ET1P@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	sugB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRR21617310_k127_1118901_4	1306406.ASHX01000001_gene4171	1.024e-138	455.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	sugA	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	iNJ661.Rv1236	BPD_transp_1
SRR21617310_k127_1118901_2	298654.FraEuI1c_4047	8.413e-149	483.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4EUHM@85013|Frankiales	201174|Actinobacteria	G	PFAM extracellular solute-binding protein family 1	lpqY	GO:0006810,GO:0008150,GO:0008643,GO:0009405,GO:0015766,GO:0015771,GO:0015772,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0071702	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_1118901_5	1380346.JNIH01000001_gene4344	4.985e-138	451.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_1118901_16	1123024.AUII01000033_gene1396	5.335e-58	209.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4E4PD@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_1118901_20	1121377.KB906404_gene2890	3.197e-31	140.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
SRR21617310_k127_1118901_18	1313172.YM304_25660	3.283e-54	203.0	COG2135@1|root,COG2135@2|Bacteria,2HGDR@201174|Actinobacteria,4CNC9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR21617310_k127_1118901_21	1173020.Cha6605_2541	1.614e-20	94.0	COG0174@1|root,COG0174@2|Bacteria,1G3HB@1117|Cyanobacteria	1117|Cyanobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR21617310_k127_1118901_0	675635.Psed_4166	4.233e-172	550.0	COG0662@1|root,COG0726@1|root,COG0662@2|Bacteria,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4E3UJ@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR21617310_k127_1118901_9	675635.Psed_4172	1.17e-121	402.0	COG1879@1|root,COG1879@2|Bacteria,2GNSF@201174|Actinobacteria,4ECTV@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR21617310_k127_1118901_10	675635.Psed_4170	2.693e-113	377.0	COG1172@1|root,COG1172@2|Bacteria,2GMJW@201174|Actinobacteria,4EAQ2@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR21617310_k127_1118901_3	675635.Psed_4171	3.326e-144	478.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4EA8T@85010|Pseudonocardiales	201174|Actinobacteria	G	SMART ATPase, AAA type, core	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR21617310_k127_1118901_19	357808.RoseRS_0048	7.1e-33	129.0	COG1335@1|root,COG1335@2|Bacteria,2G8NK@200795|Chloroflexi,37613@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR21617310_k127_1121739_0	1122611.KB903980_gene3503	2.753e-226	707.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4EFVU@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR21617310_k127_1121739_2	1449976.KALB_2853	2.944e-66	237.0	COG0819@1|root,COG0819@2|Bacteria,2I9CY@201174|Actinobacteria,4E40C@85010|Pseudonocardiales	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	-	-	-	-	-	-	-	-	-	-	-	-	TENA_THI-4
SRR21617310_k127_1121739_1	345341.KUTG_07997	1.793e-203	644.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
SRR21617310_k127_1121739_3	1068980.ARVW01000001_gene4827	1.532e-54	213.0	COG2199@1|root,COG2206@1|root,COG2206@2|Bacteria,COG3706@2|Bacteria,2GJS8@201174|Actinobacteria,4EDZE@85010|Pseudonocardiales	201174|Actinobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5
SRR21617310_k127_1121739_4	1283299.AUKG01000001_gene2404	4.132e-32	144.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR21617310_k127_1122217_4	68260.JOAY01000001_gene3599	9.052e-102	344.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR21617310_k127_1122217_7	134676.ACPL_6425	1.497e-32	143.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4DB50@85008|Micromonosporales	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_6
SRR21617310_k127_1122217_1	266117.Rxyl_0687	3.521e-142	472.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR21617310_k127_1122217_6	1155718.KB891951_gene4459	3.57e-50	199.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRR21617310_k127_1122217_2	469383.Cwoe_4858	2.892e-106	354.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1122217_0	1449346.JQMO01000003_gene3067	1.053e-248	793.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_1122217_5	1380390.JIAT01000009_gene2024	1.363e-79	284.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR21617310_k127_1122217_3	479432.Sros_7207	1.062e-103	341.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EM7U@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_1122594_2	926564.KI911656_gene1603	1.114e-35	142.0	2E2P7@1|root,32XS5@2|Bacteria,2ISG4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1122594_0	1463853.JOHW01000008_gene1130	2.151e-159	515.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR21617310_k127_1122594_1	405948.SACE_4737	2.269e-118	398.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2ICDR@201174|Actinobacteria,4E6UB@85010|Pseudonocardiales	201174|Actinobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR21617310_k127_1122594_3	1122138.AQUZ01000026_gene2918	2.173e-17	82.0	2EQYS@1|root,33IIE@2|Bacteria,2GYGJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1125286_1	1089545.KB913037_gene4004	1.611e-84	288.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR21617310_k127_1125286_2	479433.Caci_0224	5.626e-48	181.0	2EBTU@1|root,335TC@2|Bacteria,2IMRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1125286_0	436229.JOEH01000051_gene6274	2.385e-189	612.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria	201174|Actinobacteria	T	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_1125422_5	28042.GU90_18615	3.637e-31	133.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria,4E89S@85010|Pseudonocardiales	201174|Actinobacteria	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR21617310_k127_1125422_6	253839.SSNG_05100	3.612e-25	109.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_1125422_1	710111.FraQA3DRAFT_0552	1.235e-111	397.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_1125422_4	591159.ACEZ01000196_gene2789	1.764e-54	207.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_1125422_0	1449976.KALB_3986	2.56e-154	510.0	COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria,4DXWF@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
SRR21617310_k127_1125422_3	1137269.AZWL01000001_gene5625	8.962e-98	331.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR21617310_k127_1125422_2	1449976.KALB_3984	8.43e-106	365.0	COG0600@1|root,COG0600@2|Bacteria,2IBTW@201174|Actinobacteria,4EENX@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR21617310_k127_1128099_0	710696.Intca_3112	1.244e-173	550.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1128099_4	675635.Psed_6799	0.0001601	48.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria,4E37H@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_1128099_2	298655.KI912266_gene2555	3.857e-25	115.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_1128099_1	1127134.NOCYR_2798	1.621e-75	266.0	COG1708@1|root,COG1708@2|Bacteria,2GJWQ@201174|Actinobacteria,4FY28@85025|Nocardiaceae	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
SRR21617310_k127_1128099_3	419947.MRA_2760	1.039e-12	68.0	COG4422@1|root,COG4422@2|Bacteria,2GJHQ@201174|Actinobacteria,2357K@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR21617310_k127_1136459_0	1051632.TPY_2012	4.736e-219	690.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR21617310_k127_1136459_2	1051632.TPY_2010	4.137e-52	200.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_1136459_1	595494.Tola_1858	3.887e-68	243.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,1Y5SF@135624|Aeromonadales	135624|Aeromonadales	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR21617310_k127_1138303_5	1536769.P40081_07845	1.015e-06	62.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,26RF5@186822|Paenibacillaceae	91061|Bacilli	M	Collagen binding domain	M1-568	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind,Gram_pos_anchor,SdrD_B
SRR21617310_k127_1138303_3	68170.KL590470_gene10874	9.044e-124	419.0	COG4932@1|root,COG4932@2|Bacteria,2IFAA@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1138303_0	1463858.JOHR01000001_gene6338	1.511e-164	519.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR21617310_k127_1138303_4	292414.TM1040_1447	1.907e-28	125.0	COG2186@1|root,COG2186@2|Bacteria,1NXAS@1224|Proteobacteria,2V7BP@28211|Alphaproteobacteria,4NANK@97050|Ruegeria	28211|Alphaproteobacteria	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_1138303_2	1051632.TPY_2013	1.011e-134	452.0	COG0714@1|root,COG2304@1|root,COG0714@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K03924,ko:K07114	-	-	-	-	ko00000,ko01000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	AAA_5,BatA,DUF4159,VWA_2
SRR21617310_k127_1138303_1	1051632.TPY_2012	2.878e-136	458.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR21617310_k127_1141035_7	408672.NBCG_02542	4.519e-46	172.0	arCOG08699@1|root,2Z9T7@2|Bacteria,2ISG8@201174|Actinobacteria,4DV8U@85009|Propionibacteriales	201174|Actinobacteria	C	Ammonia monooxygenase/methane monooxygenase, subunit C	-	-	-	ko:K10946	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	AmoC
SRR21617310_k127_1141035_9	675635.Psed_2245	1.163e-32	140.0	COG3284@1|root,COG3284@2|Bacteria,2IANR@201174|Actinobacteria,4DZMK@85010|Pseudonocardiales	201174|Actinobacteria	KQ	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SRR21617310_k127_1141035_4	1463903.JOIZ01000010_gene3746	2.841e-80	280.0	COG3284@1|root,COG3284@2|Bacteria,2I2PU@201174|Actinobacteria	201174|Actinobacteria	KQ	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,Sigma54_activat
SRR21617310_k127_1141035_3	247490.KSU1_C1705	7.337e-99	329.0	COG1208@1|root,COG1208@2|Bacteria,2IX9K@203682|Planctomycetes	2|Bacteria	JM	Nucleotidyl transferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_1141035_0	864702.OsccyDRAFT_4169	1.74e-170	545.0	COG4976@1|root,COG4976@2|Bacteria,1GQBZ@1117|Cyanobacteria,1HHY0@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR21617310_k127_1141035_2	272134.KB731324_gene1964	4.831e-102	355.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_1141035_5	118173.KB235914_gene3827	1.11e-67	240.0	COG2120@1|root,COG2120@2|Bacteria,1G3DM@1117|Cyanobacteria,1H7V9@1150|Oscillatoriales	1117|Cyanobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR21617310_k127_1141035_6	1227739.Hsw_2787	1.778e-57	215.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR21617310_k127_1141035_1	2074.JNYD01000011_gene26	2.545e-135	443.0	2ART5@1|root,31H4G@2|Bacteria,2I83W@201174|Actinobacteria,4E9S3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1141035_8	1380355.JNIJ01000014_gene547	5.473e-43	181.0	COG3420@1|root,COG3420@2|Bacteria,1NNDG@1224|Proteobacteria,2UNM9@28211|Alphaproteobacteria,3K2HK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR21617310_k127_1141035_11	469383.Cwoe_5510	1.822e-17	94.0	COG0438@1|root,COG0438@2|Bacteria,2HENX@201174|Actinobacteria,4CRKC@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1141035_10	1172179.AUKV01000068_gene2112	6.323e-31	138.0	2E54I@1|root,32ZXG@2|Bacteria,2IK62@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR21617310_k127_114947_6	1449355.JQNR01000005_gene4007	3.364e-15	81.0	COG4758@1|root,COG4758@2|Bacteria,2GMRP@201174|Actinobacteria	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR21617310_k127_114947_3	649638.Trad_0232	6.921e-76	266.0	COG0266@1|root,COG0266@2|Bacteria,1WJ25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR21617310_k127_114947_2	404589.Anae109_2572	6.039e-79	270.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR21617310_k127_114947_4	1449353.JQMQ01000005_gene2365	4.432e-70	253.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,2NEXS@228398|Streptacidiphilus	201174|Actinobacteria	S	PHP domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR21617310_k127_114947_5	298655.KI912266_gene1981	7.617e-35	143.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4ETNH@85013|Frankiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR21617310_k127_114947_8	1122915.AUGY01000044_gene7520	3.682e-06	55.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,26Z8T@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase-like ATPase domain	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR21617310_k127_114947_7	644283.Micau_0224	1.954e-11	67.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4DEVR@85008|Micromonosporales	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_114947_1	1283283.ATXA01000003_gene1665	1.364e-93	316.0	COG0491@1|root,COG0491@2|Bacteria,2HP5U@201174|Actinobacteria,4EWTE@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_114947_0	469383.Cwoe_0102	1.74e-110	362.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4CU6B@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_1157677_0	1380394.JADL01000006_gene5276	0.0	1026.0	COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KL	DNA methylase N-4	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_N4_Mtase
SRR21617310_k127_1158928_3	477641.MODMU_1596	1.882e-21	101.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2I2QY@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1158928_0	477641.MODMU_1595	3.43e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1158928_2	1114959.SZMC14600_06687	2.052e-31	126.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4E5MK@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR21617310_k127_1158928_1	656024.FsymDg_1779	8.344e-36	144.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_1165563_0	981369.JQMJ01000004_gene4054	1.853e-176	571.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria,2NKAJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1165563_1	656024.FsymDg_0890	4.654e-39	158.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4ESC5@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR21617310_k127_1166583_1	1382356.JQMP01000003_gene1584	1.374e-137	458.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR21617310_k127_1166583_7	269800.Tfu_2950	4.533e-65	230.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1166583_3	2002.JOEQ01000013_gene5466	3.599e-98	350.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4EGQJ@85012|Streptosporangiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
SRR21617310_k127_1166583_17	525909.Afer_1115	3.854e-13	83.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1166583_11	644966.Tmar_0770	6.196e-48	180.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,24EBI@186801|Clostridia	186801|Clostridia	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR21617310_k127_1166583_12	1192124.LIG30_4393	1.27e-39	159.0	COG0208@1|root,COG0208@2|Bacteria,1QXP8@1224|Proteobacteria,2VNUB@28216|Betaproteobacteria,1KC9S@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR21617310_k127_1166583_9	105422.BBPM01000048_gene1641	1.183e-58	210.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,2NIXH@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR21617310_k127_1166583_0	234267.Acid_5269	1.241e-144	473.0	COG3391@1|root,COG3391@2|Bacteria,3Y7A2@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR21617310_k127_1166583_10	1122247.C731_4058	3.871e-55	202.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,232CW@1762|Mycobacteriaceae	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR21617310_k127_1166583_8	1449346.JQMO01000003_gene2819	1.328e-61	230.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,2M249@2063|Kitasatospora	201174|Actinobacteria	M	Mur ligase middle domain	murE	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR21617310_k127_1166583_5	67257.JODR01000014_gene5805	7.953e-85	290.0	COG4106@1|root,COG4106@2|Bacteria,2I3EG@201174|Actinobacteria	201174|Actinobacteria	S	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_1166583_2	391037.Sare_2232	1.363e-99	341.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1166583_16	101510.RHA1_ro03365	9.651e-22	103.0	COG0406@1|root,COG0406@2|Bacteria,2GXA4@201174|Actinobacteria,4G6UB@85025|Nocardiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR21617310_k127_1166583_13	749927.AMED_8155	1.372e-36	146.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4E52M@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1166583_4	1120950.KB892762_gene5477	9.96e-89	299.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4DQQW@85009|Propionibacteriales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR21617310_k127_1166583_6	1120950.KB892742_gene3009	9.781e-68	239.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4DQY9@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR21617310_k127_1166583_15	350058.Mvan_2607	1.7e-25	121.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,234UN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_1166583_14	287986.DV20_22320	8.881e-31	133.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DXZW@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_1166772_8	665577.JH993790_gene5910	2.482e-25	108.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_1166772_10	319795.Dgeo_0975	1.139e-14	77.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_1166772_4	1167006.UWK_02103	2.562e-63	229.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR21617310_k127_1166772_3	1521187.JPIM01000040_gene507	2.141e-73	273.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi,377HR@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
SRR21617310_k127_1166772_6	926550.CLDAP_03350	4.796e-60	218.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1166772_0	1125863.JAFN01000001_gene2220	3.873e-298	955.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR21617310_k127_1166772_5	1379698.RBG1_1C00001G0856	3.22e-62	224.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
SRR21617310_k127_1166772_1	1379698.RBG1_1C00001G0857	2.261e-138	453.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1166772_9	232346.JHQL01000006_gene3105	2.2e-21	96.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,1SBZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR21617310_k127_1166772_7	1906.SFRA_26615	1.213e-50	184.0	COG1553@1|root,COG1553@2|Bacteria,2IRB2@201174|Actinobacteria	201174|Actinobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
SRR21617310_k127_1166772_2	1255043.TVNIR_1705	6.632e-107	360.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_1167125_0	1237500.ANBA01000009_gene825	5.233e-69	241.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4EFJW@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR21617310_k127_1167125_1	1122919.KB905575_gene3436	2.079e-42	165.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
SRR21617310_k127_1167125_3	35754.JNYJ01000032_gene1753	0.0003702	53.0	2AUI6@1|root,31K6Q@2|Bacteria,2IKC5@201174|Actinobacteria,4DDXQ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1167125_2	365528.KB891211_gene2394	4.483e-08	60.0	COG0457@1|root,COG0457@2|Bacteria	365528.KB891211_gene2394|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1169145_2	391037.Sare_3115	4.457e-98	329.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4D8XM@85008|Micromonosporales	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_1169145_1	103733.JNYO01000034_gene2923	3.356e-126	419.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4E0Y2@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1169145_3	760192.Halhy_5770	1.921e-93	317.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes,1IWMN@117747|Sphingobacteriia	976|Bacteroidetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR21617310_k127_1169145_0	656024.FsymDg_0888	1.016e-178	585.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ERS8@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	-	-	2.6.1.1,2.6.1.17,2.6.1.2,2.6.1.66	ko:K00812,ko:K10907,ko:K14260,ko:K14267	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R04475,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_1169145_4	269800.Tfu_0877	3.131e-43	161.0	COG0117@1|root,COG0117@2|Bacteria,2IMY8@201174|Actinobacteria,4EJMQ@85012|Streptosporangiales	201174|Actinobacteria	H	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	dCMP_cyt_deam_1
SRR21617310_k127_1174452_4	1122917.KB899663_gene2635	9.76e-08	57.0	COG1309@1|root,COG1309@2|Bacteria,1VFRA@1239|Firmicutes,4I6QT@91061|Bacilli,26UCS@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1174452_0	1068980.ARVW01000001_gene4688	1.405e-74	256.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria,4E1RV@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR21617310_k127_1174452_2	1304876.AZVC01000008_gene1909	2.426e-16	91.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria,1W9MX@1268|Micrococcaceae	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR21617310_k127_1174452_3	469383.Cwoe_1001	1.211e-10	68.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria,4CT0F@84995|Rubrobacteria	84995|Rubrobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_1174452_1	1869.MB27_24050	8.476e-19	87.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4D8P2@85008|Micromonosporales	201174|Actinobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_1174465_7	1449058.JQKT01000007_gene1273	1.45e-14	75.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4FQ65@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_1174465_2	479433.Caci_3428	1.152e-38	158.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR21617310_k127_1174465_5	1133850.SHJG_3676	2.467e-21	106.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR21617310_k127_1174465_6	1961.JOAK01000007_gene4227	1.717e-18	89.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR21617310_k127_1174465_8	765420.OSCT_1847	1.273e-10	68.0	2EMAT@1|root,33EZU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1174465_4	710696.Intca_3005	1.215e-24	118.0	COG1290@1|root,COG1290@2|Bacteria,2ICE4@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_1174465_0	1120953.AUBH01000004_gene3093	2.074e-93	326.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRR21617310_k127_1175780_5	2002.JOEQ01000011_gene3965	3.381e-69	237.0	COG1959@1|root,COG1959@2|Bacteria,2IFDS@201174|Actinobacteria,4EPP5@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR21617310_k127_1175780_3	2002.JOEQ01000011_gene3964	8.311e-103	340.0	COG1359@1|root,COG1359@2|Bacteria,2IM32@201174|Actinobacteria,4EJG9@85012|Streptosporangiales	201174|Actinobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR21617310_k127_1175780_0	33898.JRHJ01000078_gene982	2.241e-142	456.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1175780_4	1246995.AFR_03360	4.051e-70	244.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria,4DJYS@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1175780_6	211165.AJLN01000084_gene1825	1.286e-67	239.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR21617310_k127_1175780_8	2002.JOEQ01000004_gene2536	1.312e-47	178.0	COG2917@1|root,COG2917@2|Bacteria,2IGTQ@201174|Actinobacteria,4EIRE@85012|Streptosporangiales	201174|Actinobacteria	D	probably involved in intracellular septation	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159,IspA
SRR21617310_k127_1175780_9	1223523.H340_01439	2.883e-37	151.0	2DRCF@1|root,33B7F@2|Bacteria,2GM2S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1175780_10	485913.Krac_3903	8.137e-22	101.0	2EACU@1|root,334GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_1175780_7	1121946.AUAX01000005_gene5502	1.18e-63	224.0	COG1309@1|root,COG1309@2|Bacteria,2ISE5@201174|Actinobacteria,4DM6H@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1175780_11	521011.Mpal_1256	4.146e-08	64.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,2N9YH@224756|Methanomicrobia	224756|Methanomicrobia	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1175780_2	345341.KUTG_02427	1.396e-105	358.0	COG2170@1|root,COG2170@2|Bacteria,2IGJN@201174|Actinobacteria,4E9EH@85010|Pseudonocardiales	201174|Actinobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR21617310_k127_1175780_1	1169161.KB897732_gene96	4.129e-108	361.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR21617310_k127_1177013_1	485913.Krac_2979	3.592e-77	261.0	COG4312@1|root,COG4312@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR21617310_k127_1177013_2	103733.JNYO01000031_gene1571	6.868e-37	146.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4E2AV@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR21617310_k127_1177013_0	349521.HCH_05222	1.114e-186	589.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RW3Z@1236|Gammaproteobacteria,1XI20@135619|Oceanospirillales	135619|Oceanospirillales	O	Pyruvate formate lyase-activating protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
SRR21617310_k127_1178112_3	644283.Micau_2740	2.135e-06	52.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DJN3@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_1178112_1	1713.JOFV01000018_gene170	6.52e-48	175.0	2E4HJ@1|root,32ZCP@2|Bacteria,2IIYC@201174|Actinobacteria,4F2Y6@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1178112_2	251229.Chro_3217	9.905e-16	84.0	COG3631@1|root,COG3631@2|Bacteria,1GD9S@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR21617310_k127_1178112_0	710696.Intca_0489	2.382e-154	501.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR21617310_k127_11795_9	1172180.KB911792_gene3687	3.222e-06	49.0	COG0569@1|root,COG0569@2|Bacteria,2HB3U@201174|Actinobacteria	201174|Actinobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR21617310_k127_11795_0	1463926.JOCA01000002_gene5648	0.0	1060.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR21617310_k127_11795_3	485913.Krac_5079	1.879e-31	126.0	COG3335@1|root,COG3335@2|Bacteria,2G8GI@200795|Chloroflexi	2|Bacteria	L	SPTR Q2LSA8 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_11795_7	1210884.HG799464_gene10364	6.406e-16	80.0	COG3335@1|root,COG3335@2|Bacteria,2IZSH@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_11795_8	1210884.HG799464_gene10857	1.109e-11	74.0	COG3415@1|root,COG3415@2|Bacteria,2J0C8@203682|Planctomycetes	2|Bacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR21617310_k127_11795_5	485913.Krac_1883	3.783e-22	101.0	COG3415@1|root,COG3415@2|Bacteria,2G91K@200795|Chloroflexi	200795|Chloroflexi	L	SPTR B0JRC2 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR21617310_k127_11795_2	867903.ThesuDRAFT_01341	2.913e-117	390.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR21617310_k127_11795_1	1122182.KB903820_gene81	1.301e-118	390.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_11795_4	1120936.KB907216_gene3862	2.12e-26	113.0	2CD8Q@1|root,338NK@2|Bacteria,2GRRS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_11795_6	1169154.KB897779_gene2947	1.329e-17	87.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_1181718_5	640132.Srot_2623	1.608e-48	175.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR21617310_k127_1181718_3	1463825.JNXC01000015_gene7486	5.379e-67	239.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria,4DY35@85010|Pseudonocardiales	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR21617310_k127_1181718_6	1246445.ANAY01000039_gene760	1.677e-45	177.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4EJ5I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR21617310_k127_1181718_4	1449355.JQNR01000003_gene629	9.422e-63	220.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR21617310_k127_1181718_9	1449353.JQMQ01000005_gene5424	1.345e-05	52.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria,2NGAN@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_1181718_0	298655.KI912266_gene1373	5.034e-191	612.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4ES67@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR21617310_k127_1181718_2	1068980.ARVW01000001_gene1580	7.397e-74	261.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DXAA@85010|Pseudonocardiales	201174|Actinobacteria	K	Phenylacetic acid-responsive transcriptional repressor	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR21617310_k127_1181718_7	211114.JOEF01000028_gene7807	2.018e-31	142.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,4E414@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_1181718_1	867903.ThesuDRAFT_00093	2.051e-90	310.0	COG0334@1|root,COG0334@2|Bacteria,1TR4Z@1239|Firmicutes,25CDT@186801|Clostridia	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR21617310_k127_1181718_8	1123023.JIAI01000019_gene2185	9.691e-22	96.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E7U5@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRR21617310_k127_11838_1	1996.JOFO01000004_gene3622	8.49e-110	372.0	COG3209@1|root,COG3209@2|Bacteria,2I35N@201174|Actinobacteria,4EIAW@85012|Streptosporangiales	201174|Actinobacteria	M	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG,PT-HINT,RHS_repeat,Ricin_B_lectin
SRR21617310_k127_11838_0	1068980.ARVW01000001_gene7039	1.037e-130	431.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria,4E03R@85010|Pseudonocardiales	201174|Actinobacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR21617310_k127_11838_3	1179773.BN6_72760	8.951e-17	87.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria,4E03R@85010|Pseudonocardiales	201174|Actinobacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR21617310_k127_11838_2	335543.Sfum_0272	1.303e-19	92.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2MSA6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_118672_3	1122611.KB903977_gene2827	3.609e-31	123.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4EFG5@85012|Streptosporangiales	201174|Actinobacteria	G	PEP-utilising enzyme, TIM barrel domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR21617310_k127_118672_2	105425.BBPL01000036_gene4376	9.375e-40	154.0	COG2323@1|root,COG2323@2|Bacteria,2IJRF@201174|Actinobacteria,2NGFD@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR21617310_k127_118672_1	1380347.JNII01000005_gene2995	2.266e-67	253.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4ES2H@85013|Frankiales	201174|Actinobacteria	F	SMART Metal-dependent phosphohydrolase, HD region	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR21617310_k127_118672_4	1120950.KB892746_gene3633	6.61e-16	85.0	COG4758@1|root,COG4758@2|Bacteria,2HP3B@201174|Actinobacteria,4DSH5@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR21617310_k127_118672_0	1463854.JOHT01000014_gene5033	6.176e-184	583.0	COG0358@1|root,COG1372@1|root,COG0358@2|Bacteria,COG1372@2|Bacteria,2GJFX@201174|Actinobacteria	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR21617310_k127_1190451_0	1463885.KL578406_gene2414	6.588e-44	170.0	COG1618@1|root,COG1618@2|Bacteria,2IJWQ@201174|Actinobacteria	201174|Actinobacteria	F	NTPase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
SRR21617310_k127_1190451_3	1463857.JOFZ01000001_gene5601	3.607e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,2GJSG@201174|Actinobacteria	201174|Actinobacteria	K	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1190451_4	68170.KL590471_gene4190	2.227e-10	70.0	COG1396@1|root,COG1396@2|Bacteria,2I40U@201174|Actinobacteria,4E3EJ@85010|Pseudonocardiales	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1190451_2	47763.JNZA01000018_gene1636	1.285e-20	98.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_1190451_1	1283283.ATXA01000012_gene4786	5.315e-33	142.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_1196467_4	1123319.AUBE01000006_gene3370	5.602e-06	56.0	COG0515@1|root,COG0515@2|Bacteria,2GN9Y@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR21617310_k127_1196467_1	469371.Tbis_1423	7.59e-82	298.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E2P2@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pkaH	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_1196467_2	211114.JOEF01000047_gene5443	1.113e-72	273.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E2P2@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_1196467_0	1133850.SHJG_5992	2.355e-230	724.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR21617310_k127_1196467_3	1120936.KB907214_gene4238	5.705e-38	156.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4EFFH@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_1196543_0	1172188.KB911820_gene2907	2.709e-17	86.0	2B30W@1|root,31VN5@2|Bacteria,2GVXJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1196543_1	365528.KB891203_gene3362	1.019e-09	67.0	2ENVJ@1|root,33GGM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1198456_1	350058.Mvan_5938	5.346e-41	155.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,239ER@1762|Mycobacteriaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1198456_0	543632.JOJL01000097_gene5165	4.929e-131	428.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1198456_4	754477.Q7C_1647	3.462e-06	56.0	COG3832@1|root,COG3832@2|Bacteria,1RD9A@1224|Proteobacteria,1S95U@1236|Gammaproteobacteria,46382@72273|Thiotrichales	72273|Thiotrichales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
SRR21617310_k127_1198456_3	1463920.JOGB01000054_gene4509	2.906e-12	70.0	2EMTZ@1|root,33FGB@2|Bacteria,2GUCW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR21617310_k127_1198456_2	1144313.PMI10_01147	2.869e-12	72.0	COG1733@1|root,COG1733@2|Bacteria,4NSVE@976|Bacteroidetes,1I4YH@117743|Flavobacteriia,2NWXC@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_1198529_0	644966.Tmar_0039	1.111e-61	228.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,3WD9Y@538999|Clostridiales incertae sedis	186801|Clostridia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR21617310_k127_1198529_4	632518.Calow_0831	5.518e-15	88.0	2DENI@1|root,2ZNKC@2|Bacteria,1W40M@1239|Firmicutes,256HE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1198529_3	1122963.AUHB01000003_gene3983	1.836e-16	93.0	COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2U9KB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Caudovirus prohead serine protease	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
SRR21617310_k127_1198529_2	644966.Tmar_0037	2.188e-47	180.0	COG2369@1|root,COG4695@1|root,COG2369@2|Bacteria,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,3WDGF@538999|Clostridiales incertae sedis	186801|Clostridia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR21617310_k127_1198529_1	644966.Tmar_0037	6.11e-51	186.0	COG2369@1|root,COG4695@1|root,COG2369@2|Bacteria,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,3WDGF@538999|Clostridiales incertae sedis	186801|Clostridia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR21617310_k127_1200293_1	1380370.JIBA01000006_gene3363	8.157e-159	522.0	COG4409@1|root,COG4409@2|Bacteria,2IEMG@201174|Actinobacteria,4FITI@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1200293_9	1449347.JQLN01000001_gene516	4.81e-16	91.0	COG1141@1|root,COG1141@2|Bacteria,2GSJ7@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
SRR21617310_k127_1200293_3	1449347.JQLN01000001_gene517	6.077e-118	392.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,2M0G3@2063|Kitasatospora	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR21617310_k127_1200293_7	675635.Psed_0744	1.878e-55	215.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,4E52U@85010|Pseudonocardiales	201174|Actinobacteria	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
SRR21617310_k127_1200293_4	1449347.JQLN01000001_gene519	2.712e-93	316.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR21617310_k127_1200293_6	1121877.JQKF01000008_gene630	1.866e-84	307.0	COG0745@1|root,COG0745@2|Bacteria,2HG0R@201174|Actinobacteria,4CNMQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1200293_5	1449976.KALB_4179	3.698e-89	311.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4DYVE@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1200293_8	392499.Swit_3583	8.975e-47	183.0	COG0665@1|root,COG0665@2|Bacteria,1R4U7@1224|Proteobacteria,2U26T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR21617310_k127_1200293_0	710421.Mycch_2937	6.771e-173	564.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR21617310_k127_1200293_2	710421.Mycch_2936	5.881e-128	415.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,23350@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_120362_6	1254432.SCE1572_13240	9.259e-08	56.0	COG2141@1|root,COG2141@2|Bacteria,1NXIH@1224|Proteobacteria,43938@68525|delta/epsilon subdivisions,2X493@28221|Deltaproteobacteria,2YYIT@29|Myxococcales	28221|Deltaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_120362_3	1157635.KB892003_gene3773	1.285e-23	108.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_120362_4	1961.JOAK01000001_gene3385	8.529e-19	92.0	COG2211@1|root,COG2211@2|Bacteria,2HH59@201174|Actinobacteria	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_120362_0	1463861.JNXE01000002_gene6613	3.782e-182	582.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR21617310_k127_120362_8	1120949.KB903295_gene2493	9.366e-07	52.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	cpsF	-	-	-	-	-	-	-	-	-	-	-	Alg14
SRR21617310_k127_120362_7	1169161.KB897752_gene2669	1.602e-07	63.0	2C3BB@1|root,2ZDF5@2|Bacteria,2IEE5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR21617310_k127_120362_1	525904.Tter_0977	2.022e-41	168.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR21617310_k127_120362_2	344747.PM8797T_00502	4.665e-40	158.0	COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR21617310_k127_120362_5	1133850.SHJG_0765	3.668e-08	66.0	COG0277@1|root,COG0277@2|Bacteria,2I40C@201174|Actinobacteria	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1206089_1	1237500.ANBA01000003_gene4741	3.314e-58	223.0	COG3740@1|root,COG3740@2|Bacteria,2GYHG@201174|Actinobacteria	201174|Actinobacteria	S	Caudovirus prohead serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78
SRR21617310_k127_1206089_0	68170.KL590474_gene5932	8.042e-93	312.0	COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria	201174|Actinobacteria	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR21617310_k127_1206185_0	68170.KL590474_gene5932	2.066e-92	311.0	COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria	201174|Actinobacteria	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR21617310_k127_1206185_1	1237500.ANBA01000003_gene4741	2.323e-59	223.0	COG3740@1|root,COG3740@2|Bacteria,2GYHG@201174|Actinobacteria	201174|Actinobacteria	S	Caudovirus prohead serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78
SRR21617310_k127_1207052_5	153721.MYP_3631	0.000973	53.0	COG3209@1|root,COG4447@1|root,COG3209@2|Bacteria,COG4447@2|Bacteria,4NE5D@976|Bacteroidetes,47MBZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR,SprB
SRR21617310_k127_1207052_0	1394178.AWOO02000103_gene5698	3.747e-203	650.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EG9Z@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR21617310_k127_1207052_4	284031.JNXD01000029_gene1085	1.227e-11	70.0	2DPU0@1|root,333DA@2|Bacteria,2GKVP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1207052_1	471852.Tcur_1745	1.429e-135	443.0	COG2234@1|root,COG2234@2|Bacteria,2I9S8@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR21617310_k127_1207052_2	467200.ACFA01000004_gene1804	1.242e-64	232.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR21617310_k127_1207052_3	1121272.KB903281_gene6984	7.491e-36	140.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8SS@85008|Micromonosporales	201174|Actinobacteria	V	resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_1212455_0	1449976.KALB_468	2.885e-124	411.0	COG1653@1|root,COG1653@2|Bacteria,2GJYT@201174|Actinobacteria,4DYRH@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_1212455_3	285535.JOEY01000056_gene6772	4.829e-96	324.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR21617310_k127_1212455_1	1968.JOEV01000005_gene6127	7.115e-97	328.0	COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR21617310_k127_1212455_4	1121012.AUKX01000010_gene2021	2.319e-84	303.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1HZRG@117743|Flavobacteriia,23G6Y@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR21617310_k127_1212455_2	1120949.KB903322_gene2758	2.199e-96	326.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR21617310_k127_1212455_5	1169161.KB897738_gene2602	5.382e-43	164.0	COG2259@1|root,COG2259@2|Bacteria,2IMX8@201174|Actinobacteria	201174|Actinobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR21617310_k127_1214337_6	296591.Bpro_2063	6.005e-10	64.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,4ACE5@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR21617310_k127_1214337_5	935548.KI912159_gene3570	5.829e-11	66.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,2TTSN@28211|Alphaproteobacteria,43NTJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1214337_1	110319.CF8_0130	1.586e-107	355.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DNUY@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR21617310_k127_1214337_3	1229780.BN381_10220	1.327e-83	296.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR21617310_k127_1214337_7	208439.AJAP_18435	0.0004561	52.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1214337_4	1449353.JQMQ01000005_gene1304	7.499e-69	253.0	COG0697@1|root,COG0697@2|Bacteria,2GMPU@201174|Actinobacteria,2NM79@228398|Streptacidiphilus	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1214337_0	1380346.JNIH01000011_gene2702	8.636e-163	526.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1214337_2	1089545.KB913037_gene4332	2.685e-87	319.0	COG1396@1|root,COG1396@2|Bacteria,2GJXM@201174|Actinobacteria,4E9QB@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1216218_6	298653.Franean1_7081	5.704e-14	80.0	COG4584@1|root,COG4584@2|Bacteria,2GZ8H@201174|Actinobacteria,4EWKX@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	istA	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
SRR21617310_k127_1216218_0	222534.KB893681_gene1083	1.206e-99	337.0	COG4584@1|root,COG4584@2|Bacteria,2GZ8H@201174|Actinobacteria,4EWKX@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	istA	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
SRR21617310_k127_1216218_1	222534.KB893681_gene1083	1.186e-68	243.0	COG4584@1|root,COG4584@2|Bacteria,2GZ8H@201174|Actinobacteria,4EWKX@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	istA	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
SRR21617310_k127_1216218_4	1172186.KB911469_gene2565	2.314e-28	124.0	COG2267@1|root,COG2267@2|Bacteria,2IH5C@201174|Actinobacteria,23BUX@1762|Mycobacteriaceae	201174|Actinobacteria	I	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR21617310_k127_1216218_3	443218.AS9A_1913	3.604e-38	150.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,2344U@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	acnR	GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21962	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR21617310_k127_1216218_2	288705.RSal33209_0922	5.363e-44	172.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z5@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	-
SRR21617310_k127_1216218_5	35754.JNYJ01000011_gene731	1.237e-20	104.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4DBVQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SRR21617310_k127_1218207_3	1179773.BN6_78620	1.773e-30	126.0	COG0789@1|root,COG0789@2|Bacteria,2I8T8@201174|Actinobacteria,4DZZC@85010|Pseudonocardiales	201174|Actinobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
SRR21617310_k127_1218207_1	2002.JOEQ01000040_gene6066	6.885e-109	371.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4EGJY@85012|Streptosporangiales	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR21617310_k127_1218207_0	2002.JOEQ01000040_gene6067	1.416e-184	591.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4EFHW@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR21617310_k127_1218207_2	1123320.KB889675_gene3878	1.385e-80	284.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR21617310_k127_1223234_11	1408254.T458_11560	5.356e-07	55.0	COG4916@1|root,COG4916@2|Bacteria,1VAWI@1239|Firmicutes,4IBCQ@91061|Bacilli,2742C@186822|Paenibacillaceae	91061|Bacilli	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR21617310_k127_1223234_9	1408303.JNJJ01000067_gene2262	8.56e-18	91.0	COG1940@1|root,COG1940@2|Bacteria,1TTAI@1239|Firmicutes,4HCWA@91061|Bacilli,1ZRHA@1386|Bacillus	91061|Bacilli	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,ROK
SRR21617310_k127_1223234_7	1307761.L21SP2_3483	2.689e-21	104.0	COG1940@1|root,COG1940@2|Bacteria,2J89S@203691|Spirochaetes	203691|Spirochaetes	GK	ROK family	xylR-2	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR21617310_k127_1223234_1	2002.JOEQ01000025_gene239	1.456e-69	243.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria,4EKCC@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR21617310_k127_1223234_4	671143.DAMO_0703	2.985e-54	203.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249	2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1	ko:K00574,ko:K07154,ko:K14369,ko:K15257,ko:K18534	ko00130,ko00522,ko01100,ko01110,ko01130,map00130,map00522,map01100,map01110,map01130	M00112,M00774	R05520,R05532,R07501,R10709,R10710	RC00003,RC01324,RC01662	ko00000,ko00001,ko00002,ko01000,ko01001,ko01008,ko02048,ko03016	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR21617310_k127_1223234_3	1380390.JIAT01000010_gene4351	3.592e-57	211.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR21617310_k127_1223234_2	351607.Acel_0232	2.02e-62	229.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria,4ET75@85013|Frankiales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
SRR21617310_k127_1223234_5	945713.IALB_0843	4.611e-26	124.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
SRR21617310_k127_1223234_0	1000565.METUNv1_00935	1.988e-80	280.0	COG0469@1|root,COG2046@1|root,COG0469@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria,2KYGT@206389|Rhodocyclales	206389|Rhodocyclales	H	PUA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-sulfurylase,PK,PUA_2
SRR21617310_k127_1223234_6	1379270.AUXF01000001_gene2611	4.71e-23	108.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
SRR21617310_k127_1223234_8	1121324.CLIT_14c01330	8.241e-20	104.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25SG4@186804|Peptostreptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
SRR21617310_k127_1237639_8	471853.Bcav_1040	1.667e-39	159.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria	201174|Actinobacteria	IQ	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1237639_10	479432.Sros_1613	2.461e-05	49.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4EG4G@85012|Streptosporangiales	201174|Actinobacteria	L	FAD binding domain of DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR21617310_k127_1237639_3	1240349.ANGC01000036_gene3275	7.806e-85	287.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,4G0G6@85025|Nocardiaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR21617310_k127_1237639_0	675635.Psed_4169	6.9e-232	730.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DZ94@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR21617310_k127_1237639_7	82508.K1VDR3	8.513e-40	164.0	COG1250@1|root,KOG2304@2759|Eukaryota	2759|Eukaryota	I	3-hydroxyacyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,zf-C3HC4_3
SRR21617310_k127_1237639_9	1343740.M271_00320	3.191e-18	95.0	COG3971@1|root,COG3971@2|Bacteria,2GPBI@201174|Actinobacteria	201174|Actinobacteria	Q	hydratase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
SRR21617310_k127_1237639_2	882082.SaccyDRAFT_3038	5.374e-171	543.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DZWM@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR21617310_k127_1237639_1	469371.Tbis_2222	6.239e-177	568.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2GNP7@201174|Actinobacteria,4E0S8@85010|Pseudonocardiales	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accDA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR21617310_k127_1237639_4	882083.SacmaDRAFT_2417	4.091e-80	274.0	COG2186@1|root,COG2186@2|Bacteria,2I91R@201174|Actinobacteria,4E1U4@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR21617310_k127_1237639_6	296591.Bpro_0708	5.271e-50	202.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1PF0H@1224|Proteobacteria,2W8ZC@28216|Betaproteobacteria,4AI7H@80864|Comamonadaceae	28216|Betaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,MASE1
SRR21617310_k127_1237639_5	357808.RoseRS_2684	4.637e-65	227.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi,37610@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR21617310_k127_1238571_5	219305.MCAG_01973	1.22e-91	306.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4D9AV@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1238571_6	469383.Cwoe_1650	3.338e-76	273.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CRNY@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,PspC
SRR21617310_k127_1238571_12	1521187.JPIM01000112_gene2333	0.0001534	52.0	COG1983@1|root,COG1983@2|Bacteria,2G9IZ@200795|Chloroflexi,377SB@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR21617310_k127_1238571_9	1123320.KB889688_gene463	4.889e-30	139.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria	201174|Actinobacteria	KT	PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRR21617310_k127_1238571_1	1380347.JNII01000008_gene4099	9.316e-190	614.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4EREV@85013|Frankiales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR21617310_k127_1238571_4	525904.Tter_2591	3.161e-100	353.0	COG0276@1|root,COG0276@2|Bacteria,2NQ0V@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Chloroa_b-bind,Ferrochelatase
SRR21617310_k127_1238571_2	525904.Tter_2590	8.254e-149	482.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRR21617310_k127_1238571_8	211114.JOEF01000011_gene5182	9.333e-40	157.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4E2MZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_1238571_0	1463864.JOGO01000008_gene314	8.664e-206	650.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR21617310_k127_1238571_10	378806.STAUR_7249	1.214e-18	92.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,43AAS@68525|delta/epsilon subdivisions,2X59J@28221|Deltaproteobacteria,2Z0AR@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1238571_3	656024.FsymDg_0502	1.691e-120	411.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_1238571_7	1463861.JNXE01000001_gene5474	5.477e-42	166.0	COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria	201174|Actinobacteria	S	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
SRR21617310_k127_1238571_11	1122611.KB903976_gene2748	2.36e-07	52.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4EHWC@85012|Streptosporangiales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR21617310_k127_1250186_1	1120950.KB892783_gene333	1.567e-139	479.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DQGN@85009|Propionibacteriales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,TPR_7,TPR_8,Trans_reg_C
SRR21617310_k127_1250186_6	390989.JOEG01000002_gene4371	1.254e-12	76.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria,4DEJJ@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_1250186_5	1089546.AQUI01000002_gene3285	3.211e-16	79.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	tnpA	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_1250186_7	1108045.GORHZ_247_00020	2.311e-09	61.0	COG1061@1|root,COG1061@2|Bacteria,2H66X@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1250186_0	711393.AYRX01000083_gene4753	2.923e-237	745.0	COG5421@1|root,COG5421@2|Bacteria,2GK2A@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR21617310_k127_1250186_3	105425.BBPL01000059_gene5048	4.746e-40	159.0	COG1409@1|root,COG1409@2|Bacteria,2HKQQ@201174|Actinobacteria,2NFXM@228398|Streptacidiphilus	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR21617310_k127_1250186_4	1394178.AWOO02000020_gene7455	3.966e-26	111.0	COG1409@1|root,COG1409@2|Bacteria,2HKQQ@201174|Actinobacteria,4EIIK@85012|Streptosporangiales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR21617310_k127_1258299_1	1122611.KB903940_gene1759	3.105e-142	474.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4EGEU@85012|Streptosporangiales	201174|Actinobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR21617310_k127_1258299_0	345341.KUTG_01741	1.57e-153	493.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4DXG6@85010|Pseudonocardiales	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_1258299_5	436308.Nmar_0262	2.573e-13	75.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR21617310_k127_1258299_3	309801.trd_A0538	2.014e-103	348.0	COG2159@1|root,COG2159@2|Bacteria,2G89Y@200795|Chloroflexi,27XQB@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_1258299_4	1343740.M271_48300	2.3e-63	229.0	COG1477@1|root,COG1477@2|Bacteria,2GN6F@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR21617310_k127_1258299_6	450380.JPSY01000001_gene1026	1.364e-12	78.0	COG3976@1|root,COG3976@2|Bacteria,2GTTI@201174|Actinobacteria,4FQE4@85023|Microbacteriaceae	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
SRR21617310_k127_1258299_2	1449347.JQLN01000007_gene1838	4.965e-126	418.0	COG1018@1|root,COG1018@2|Bacteria,2HE37@201174|Actinobacteria,2M269@2063|Kitasatospora	201174|Actinobacteria	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
SRR21617310_k127_1258568_3	1449347.JQLN01000003_gene5876	0.000156	51.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,2M44M@2063|Kitasatospora	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1258568_2	2074.JNYD01000015_gene4513	4.25e-17	83.0	29VD5@1|root,30GTT@2|Bacteria,2GXTA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR21617310_k127_1258568_0	2074.JNYD01000003_gene3439	3.498e-202	640.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4E9Y4@85010|Pseudonocardiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR21617310_k127_1258568_1	1230476.C207_05760	3.001e-36	139.0	COG1917@1|root,COG1917@2|Bacteria,1RCXV@1224|Proteobacteria,2U6MY@28211|Alphaproteobacteria,3JYZJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1259941_1	356851.JOAN01000003_gene1451	1.482e-22	101.0	COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria	201174|Actinobacteria	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR21617310_k127_1259941_0	566461.SSFG_01018	5.075e-135	448.0	COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR21617310_k127_1259941_2	266940.Krad_1724	9.015e-22	100.0	2EIV5@1|root,33CKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1260448_1	1380386.JIAW01000030_gene3589	7.356e-90	306.0	COG1840@1|root,COG1840@2|Bacteria,2GUG5@201174|Actinobacteria,23EGG@1762|Mycobacteriaceae	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR21617310_k127_1260448_4	1380386.JIAW01000030_gene3590	9.044e-27	126.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2392Z@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1,SBP_bac_6
SRR21617310_k127_1260448_6	1380386.JIAW01000030_gene3591	1.822e-15	86.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,23CXF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR21617310_k127_1260448_3	1463857.JOFZ01000005_gene3356	3.906e-75	259.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_25
SRR21617310_k127_1260448_5	1463857.JOFZ01000005_gene3355	8.732e-20	93.0	2DWN2@1|root,3414B@2|Bacteria,2IC7M@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1260448_0	1463857.JOFZ01000005_gene3355	4.212e-137	445.0	2DWN2@1|root,3414B@2|Bacteria,2IC7M@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1260448_2	263358.VAB18032_03395	5.306e-88	294.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DBRK@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_1268765_2	211114.JOEF01000022_gene5595	3.372e-24	108.0	2B60G@1|root,31YWQ@2|Bacteria,2H1CW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1268765_1	105422.BBPM01000016_gene2227	2.755e-31	130.0	2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria	201174|Actinobacteria	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
SRR21617310_k127_1268765_0	211114.JOEF01000022_gene5596	8.201e-61	214.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	u35	-	-	-	-	-	-	-	-	-	-	-	Mu-like_gpT,NYN,Peptidase_S78
SRR21617310_k127_1272079_3	1122611.KB903941_gene2115	4.99e-28	118.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4EG6Y@85012|Streptosporangiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR21617310_k127_1272079_2	1463934.JOCF01000015_gene564	1.812e-47	191.0	COG4409@1|root,COG4409@2|Bacteria,2H1PD@201174|Actinobacteria	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1272079_1	1380390.JIAT01000009_gene2268	2.72e-132	431.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR21617310_k127_1272079_0	1160718.SU9_33043	9.639e-162	534.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SRR21617310_k127_12753_16	888439.HMPREF9240_00458	3.861e-11	64.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4D38H@85005|Actinomycetales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR21617310_k127_12753_9	748449.Halha_2028	7.372e-83	287.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WAAJ@53433|Halanaerobiales	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR21617310_k127_12753_13	479434.Sthe_1634	8.357e-39	153.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,27YBK@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR21617310_k127_12753_18	525909.Afer_1840	0.0008193	51.0	COG1135@1|root,COG1135@2|Bacteria,2HH1B@201174|Actinobacteria,4CP1I@84992|Acidimicrobiia	84992|Acidimicrobiia	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
SRR21617310_k127_12753_10	28444.JODQ01000010_gene3087	2.742e-71	253.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
SRR21617310_k127_12753_0	67315.JOBD01000007_gene3499	6.301e-275	852.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR21617310_k127_12753_4	321332.CYB_2820	9.109e-126	415.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria,1GZEW@1129|Synechococcus	1117|Cyanobacteria	H	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_12753_8	665571.STHERM_c02540	8.06e-88	305.0	COG1215@1|root,COG1215@2|Bacteria,2J64X@203691|Spirochaetes	203691|Spirochaetes	M	Glycosyl transferase family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR21617310_k127_12753_12	326424.FRAAL6699	2.342e-41	163.0	COG0561@1|root,COG0561@2|Bacteria,2IRCG@201174|Actinobacteria,4EUX0@85013|Frankiales	201174|Actinobacteria	S	Haloacid dehalogenase domain protein hydrolase, type 3	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR21617310_k127_12753_3	561175.KB894099_gene4906	2.432e-139	458.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4EGDH@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR21617310_k127_12753_15	1380356.JNIK01000011_gene1765	1.077e-20	102.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR21617310_k127_12753_11	1122609.AUGT01000012_gene4242	3.526e-46	181.0	COG0791@1|root,COG1196@1|root,COG0791@2|Bacteria,COG1196@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_12753_14	1120934.KB894414_gene3817	7.885e-37	154.0	COG0501@1|root,COG0501@2|Bacteria,2GTHQ@201174|Actinobacteria,4E8U9@85010|Pseudonocardiales	201174|Actinobacteria	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
SRR21617310_k127_12753_1	211114.JOEF01000004_gene6445	2.135e-225	709.0	COG1953@1|root,COG1953@2|Bacteria,2GJXN@201174|Actinobacteria,4DZ1Q@85010|Pseudonocardiales	201174|Actinobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR21617310_k127_12753_5	485913.Krac_11396	1.567e-119	396.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_12753_6	234267.Acid_7663	2.75e-111	375.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR21617310_k127_12753_2	2074.JNYD01000027_gene7392	1.768e-182	581.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4DXP0@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR21617310_k127_12753_17	298653.Franean1_4658	8.514e-07	52.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_12753_7	457429.ABJI02000835_gene2509	3.594e-93	321.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_1277474_2	448385.sce0688	1.038e-108	364.0	COG2304@1|root,COG2374@1|root,COG3509@1|root,COG2304@2|Bacteria,COG2374@2|Bacteria,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	rapB1	GO:0005575,GO:0005576	3.2.1.8	ko:K01181,ko:K07004,ko:K12548	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Exo_endo_phos
SRR21617310_k127_1277474_3	1122138.AQUZ01000057_gene6686	2.209e-99	338.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DPNR@85009|Propionibacteriales	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR21617310_k127_1277474_0	570268.ANBB01000041_gene1635	3.559e-188	601.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4EHDH@85012|Streptosporangiales	201174|Actinobacteria	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR21617310_k127_1277474_1	44060.JODL01000030_gene969	7.159e-175	556.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria	201174|Actinobacteria	E	4-hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR21617310_k127_1277474_4	526225.Gobs_1925	2.315e-43	173.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,4ET5P@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_1277474_5	1089544.KB912942_gene214	9.925e-28	116.0	2DSM3@1|root,33GM1@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_1282650_1	33876.JNXY01000018_gene7749	3.586e-127	421.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4D8FV@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_1282650_7	1051632.TPY_3784	3.755e-48	190.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,24GE9@186801|Clostridia	186801|Clostridia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR21617310_k127_1282650_2	446470.Snas_4893	1.137e-112	376.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4EY08@85014|Glycomycetales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR21617310_k127_1282650_13	1214101.BN159_3102	2.017e-25	107.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,Sigma70_r4_2
SRR21617310_k127_1282650_11	408672.NBCG_05546	4.482e-39	152.0	COG0542@1|root,COG0542@2|Bacteria,2IRV0@201174|Actinobacteria,4DUYP@85009|Propionibacteriales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR21617310_k127_1282650_0	298653.Franean1_1770	9.315e-232	725.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4ES5H@85013|Frankiales	201174|Actinobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR21617310_k127_1282650_19	33898.JRHJ01000042_gene3595	0.0002626	45.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_1282650_20	405948.SACE_0358	0.0004335	47.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria,4E53M@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1282650_4	1122611.KB903959_gene4205	7.319e-53	192.0	COG3467@1|root,COG3467@2|Bacteria,2IAMC@201174|Actinobacteria,4EPKB@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR21617310_k127_1282650_5	211114.JOEF01000031_gene1889	3.31e-49	182.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4E2UF@85010|Pseudonocardiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1282650_14	344747.PM8797T_12733	2.197e-24	113.0	COG0457@1|root,COG0457@2|Bacteria,2J3ZR@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1282650_3	994479.GL877878_gene3083	2.582e-103	355.0	COG4467@1|root,COG4467@2|Bacteria,2IDK7@201174|Actinobacteria	201174|Actinobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_1282650_17	222534.KB893767_gene4799	2.826e-09	63.0	COG3593@1|root,COG3593@2|Bacteria,2ICNW@201174|Actinobacteria	201174|Actinobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
SRR21617310_k127_1282650_10	649831.L083_7931	8.597e-42	155.0	COG1324@1|root,COG1324@2|Bacteria	2|Bacteria	P	tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840	4.2.3.1	ko:K01733,ko:K03926	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	CutA1
SRR21617310_k127_1282650_15	1122611.KB903999_gene8177	1.438e-14	79.0	2C56A@1|root,32RF5@2|Bacteria,2IP97@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR21617310_k127_1282650_21	1463887.KL590079_gene3778	0.000941	51.0	COG3415@1|root,COG3415@2|Bacteria,2I2W7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR21617310_k127_1282650_12	1089545.KB913037_gene1679	1.161e-30	128.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_1282650_8	1125971.ASJB01000043_gene3201	7.56e-48	177.0	COG1309@1|root,COG1309@2|Bacteria,2GNK4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_1282650_6	1183438.GKIL_4041	3.847e-49	186.0	COG0702@1|root,COG0702@2|Bacteria,1G3KV@1117|Cyanobacteria	1117|Cyanobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR21617310_k127_1282650_9	208439.AJAP_30920	3.299e-43	175.0	2CK59@1|root,32RQ2@2|Bacteria,2IFCF@201174|Actinobacteria,4ECHV@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_1282650_16	479431.Namu_0438	4.853e-12	74.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EV7U@85013|Frankiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_1282650_18	1394178.AWOO02000033_gene8458	2.213e-06	55.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_1287482_5	526225.Gobs_0787	1.657e-23	100.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4ESHD@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR21617310_k127_1287482_4	67352.JODS01000022_gene3665	3.843e-28	121.0	2F8ME@1|root,340ZZ@2|Bacteria,2IJJP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1287482_3	926550.CLDAP_31780	2.291e-85	292.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR21617310_k127_1287482_2	33876.JNXY01000014_gene3934	1.902e-122	406.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DCEX@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR21617310_k127_1287482_1	33876.JNXY01000014_gene3932	1.842e-130	424.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DCYX@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR21617310_k127_1287482_0	263358.VAB18032_09415	3.062e-134	436.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DAJR@85008|Micromonosporales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_1291976_0	298654.FraEuI1c_2442	1.183e-197	628.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_1291976_13	926550.CLDAP_37690	2.925e-52	192.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR21617310_k127_1291976_25	316056.RPC_4612	5.209e-08	63.0	COG0835@1|root,COG0835@2|Bacteria,1RETU@1224|Proteobacteria,2U87V@28211|Alphaproteobacteria,3JVTB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR21617310_k127_1291976_16	208439.AJAP_30250	1.749e-47	176.0	COG1853@1|root,COG1853@2|Bacteria,2GMPH@201174|Actinobacteria,4E4PC@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	ko:K21185	ko01059,ko01130,map01059,map01130	M00827,M00828,M00832	R11368,R11393	RC00949,RC03431	ko00000,ko00001,ko00002	-	-	-	Flavin_Reduct
SRR21617310_k127_1291976_12	278957.ABEA03000212_gene3802	6.68e-55	208.0	COG0035@1|root,COG0035@2|Bacteria,46ST2@74201|Verrucomicrobia,3K7WA@414999|Opitutae	414999|Opitutae	F	uracil phosphoribosyltransferase	-	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR21617310_k127_1291976_17	269800.Tfu_0864	2.991e-39	154.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4ENS4@85012|Streptosporangiales	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR21617310_k127_1291976_8	1133849.O3I_032845	1.181e-107	359.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4FWTY@85025|Nocardiaceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR21617310_k127_1291976_1	1304865.JAGF01000001_gene190	2.53e-194	618.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4F0DM@85016|Cellulomonadaceae	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR21617310_k127_1291976_6	1120950.KB892760_gene5784	4.186e-115	393.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4DNPP@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR21617310_k127_1291976_5	390989.JOEG01000023_gene5747	4.678e-119	404.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4D974@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR21617310_k127_1291976_11	644966.Tmar_1316	6.504e-66	248.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WCVP@538999|Clostridiales incertae sedis	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR21617310_k127_1291976_23	477641.MODMU_4151	1.155e-13	85.0	COG4603@1|root,COG4603@2|Bacteria,2GMKB@201174|Actinobacteria	201174|Actinobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR21617310_k127_1291976_18	867903.ThesuDRAFT_01559	2.637e-37	154.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WDC9@538999|Clostridiales incertae sedis	186801|Clostridia	P	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR21617310_k127_1291976_3	269799.Gmet_0122	7.163e-123	409.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43TCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	Fer4_9,PK,PK_C
SRR21617310_k127_1291976_22	1380370.JIBA01000012_gene3541	1.249e-17	89.0	2EHZA@1|root,33BQS@2|Bacteria,2IJZ0@201174|Actinobacteria,4FGP6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1291976_21	926560.KE387023_gene2416	4.754e-22	101.0	COG2197@1|root,COG2197@2|Bacteria,1WJSB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1291976_10	1009370.ALO_00115	6.478e-83	292.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H6XZ@909932|Negativicutes	909932|Negativicutes	E	carbamate kinase	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR21617310_k127_1291976_14	561175.KB894094_gene1456	1.638e-50	198.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria,4EIMY@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1291976_4	298653.Franean1_2532	5.9e-120	392.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EUCH@85013|Frankiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR21617310_k127_1291976_20	351607.Acel_0951	1.068e-23	112.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria,4EWW3@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1291976_9	469371.Tbis_1280	1.471e-84	289.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4E7TG@85010|Pseudonocardiales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR21617310_k127_1291976_2	2002.JOEQ01000007_gene1914	1.484e-142	470.0	COG0215@1|root,COG0215@2|Bacteria,2IDHB@201174|Actinobacteria,4EN5K@85012|Streptosporangiales	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
SRR21617310_k127_1291976_15	306537.jk1395	1.086e-49	182.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,22N7C@1653|Corynebacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fer4
SRR21617310_k127_1291976_7	1229780.BN381_310078	1.989e-113	377.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR21617310_k127_1291976_24	1121272.KB903261_gene6339	2.884e-08	63.0	2DRJD@1|root,33C0U@2|Bacteria,2IQVG@201174|Actinobacteria,4DEXW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1291976_19	395493.BegalDRAFT_1252	6.995e-25	107.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,1S9F8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1293283_0	1122611.KB903939_gene389	1.699e-133	447.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4EFPH@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR21617310_k127_1293283_4	1192034.CAP_1582	6.051e-67	236.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR21617310_k127_1293283_3	1211815.CBYP010000047_gene1618	2.517e-76	267.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4ESBC@85013|Frankiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR21617310_k127_1293283_1	219305.MCAG_04305	1.824e-128	416.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DHNE@85008|Micromonosporales	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_1293283_2	1120936.KB907224_gene2611	4.039e-80	295.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4EIDY@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1294658_1	479432.Sros_4203	3.602e-44	184.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4ENKK@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR21617310_k127_1294658_4	298655.KI912266_gene4753	2.411e-24	111.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_1294658_2	298653.Franean1_0402	3.572e-41	155.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_1294658_3	298653.Franean1_4376	2.318e-38	154.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_1294658_6	1121877.JQKF01000006_gene924	1.673e-10	63.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_1294658_0	298653.Franean1_3066	7.523e-62	216.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_1294658_5	298653.Franean1_3066	5.462e-14	73.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_1294772_5	485913.Krac_6773	3.855e-09	59.0	COG1940@1|root,COG1940@2|Bacteria,2G8NY@200795|Chloroflexi	200795|Chloroflexi	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
SRR21617310_k127_1294772_2	926550.CLDAP_10160	2.915e-134	442.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR21617310_k127_1294772_0	1968.JOEV01000005_gene6126	1.581e-160	516.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria	201174|Actinobacteria	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
SRR21617310_k127_1294772_3	1157637.KB892090_gene5931	3.964e-79	286.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria	201174|Actinobacteria	G	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR21617310_k127_1294772_1	1236902.ANAS01000037_gene5387	7.397e-143	467.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EH24@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR21617310_k127_1294772_6	266940.Krad_3992	3.596e-05	52.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1294772_4	67267.JNXT01000003_gene3980	6.742e-48	179.0	COG1444@1|root,COG1444@2|Bacteria,2IMCJ@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_1295787_1	298653.Franean1_4521	3.533e-88	295.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4EUED@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR21617310_k127_1295787_3	1121468.AUBR01000095_gene761	2.812e-46	181.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR21617310_k127_1295787_0	643648.Slip_0897	3.336e-118	385.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42JJA@68298|Syntrophomonadaceae	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR21617310_k127_1295787_4	525909.Afer_0488	3.761e-20	102.0	COG2331@1|root,COG2331@2|Bacteria,2HGEB@201174|Actinobacteria,4CP29@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1295787_2	1120936.KB907218_gene3396	1.258e-79	295.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4EHMP@85012|Streptosporangiales	201174|Actinobacteria	D	AAA domain	espI	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044315,GO:0044419,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
SRR21617310_k127_1296555_0	471852.Tcur_1271	0.0	1106.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4EGX0@85012|Streptosporangiales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR21617310_k127_1296555_3	390989.JOEG01000003_gene4676	4.666e-123	410.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4D98Q@85008|Micromonosporales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR21617310_k127_1296555_2	335543.Sfum_0297	2.611e-177	573.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	nonribosomal peptide	matB	-	6.2.1.3	ko:K00666,ko:K01897,ko:K18660,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_1296555_1	1449353.JQMQ01000004_gene6257	2.033e-218	691.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,2NHEP@228398|Streptacidiphilus	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_1296555_4	1111479.AXAR01000001_gene77	1.971e-72	266.0	COG1028@1|root,COG1028@2|Bacteria,1TS0K@1239|Firmicutes,4HA78@91061|Bacilli	91061|Bacilli	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_1296555_7	47763.JNZA01000017_gene1423	1.896e-22	100.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_1296555_5	1123274.KB899412_gene1486	5.078e-57	216.0	COG3391@1|root,COG3391@2|Bacteria,2J5ZD@203691|Spirochaetes	203691|Spirochaetes	S	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR21617310_k127_1302596_3	469383.Cwoe_3000	6.971e-55	201.0	COG3324@1|root,COG3324@2|Bacteria,2GPAS@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_1302596_0	926560.KE387023_gene1619	2.075e-118	390.0	COG3227@1|root,COG3227@2|Bacteria,1WMD9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1302596_4	1306990.BARG01000159_gene10575	2.605e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,2ID45@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1302596_1	345341.KUTG_09499	1.204e-103	345.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4E5TR@85010|Pseudonocardiales	201174|Actinobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR
SRR21617310_k127_1302596_7	1146883.BLASA_4882	8.083e-23	107.0	COG3945@1|root,COG4309@1|root,COG3945@2|Bacteria,COG4309@2|Bacteria,2GS7C@201174|Actinobacteria,4ETE4@85013|Frankiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
SRR21617310_k127_1302596_2	494419.ALPM01000063_gene2210	3.575e-102	340.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,1W9FM@1268|Micrococcaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR21617310_k127_1302596_9	33876.JNXY01000017_gene7235	0.0001484	47.0	COG1714@1|root,COG1714@2|Bacteria,2HWNZ@201174|Actinobacteria,4DJRD@85008|Micromonosporales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR21617310_k127_1302596_5	35754.JNYJ01000033_gene2594	1.313e-37	149.0	COG0454@1|root,COG0456@2|Bacteria,2ISWJ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_1302596_6	1121272.KB903283_gene5145	3.776e-26	119.0	COG1846@1|root,COG1846@2|Bacteria,2HX18@201174|Actinobacteria,4DKY6@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1303833_3	1380386.JIAW01000030_gene3591	1.176e-92	309.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,23CXF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR21617310_k127_1303833_2	1120949.KB903294_gene4213	2.227e-95	323.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR21617310_k127_1303833_4	1380386.JIAW01000030_gene3592	2.594e-11	75.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR21617310_k127_1303833_0	1547437.LL06_00290	1.755e-222	707.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_1303833_1	1380386.JIAW01000030_gene3585	5.224e-183	577.0	COG3435@1|root,COG3435@2|Bacteria,2IE81@201174|Actinobacteria,236XY@1762|Mycobacteriaceae	201174|Actinobacteria	Q	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1306748_1	1146883.BLASA_0208	3.258e-178	570.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4EU3Z@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR21617310_k127_1306748_12	35754.JNYJ01000075_gene8654	4.942e-08	59.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DAJX@85008|Micromonosporales	201174|Actinobacteria	C	Cytochrome b	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_1306748_11	1120949.KB903317_gene1735	1.092e-08	58.0	COG2197@1|root,COG2197@2|Bacteria,2H7AA@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR21617310_k127_1306748_4	1380390.JIAT01000010_gene4303	9.054e-130	427.0	COG0247@1|root,COG0247@2|Bacteria,2H9RN@201174|Actinobacteria	201174|Actinobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	1.1.5.3	ko:K00113,ko:K18930	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
SRR21617310_k127_1306748_6	1380390.JIAT01000010_gene4302	1.084e-64	243.0	COG3075@1|root,COG3075@2|Bacteria,2GMNS@201174|Actinobacteria	201174|Actinobacteria	E	Glycerol-3-phosphate dehydrogenase	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
SRR21617310_k127_1306748_3	357808.RoseRS_3299	2.643e-135	464.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
SRR21617310_k127_1306748_5	1380390.JIAT01000010_gene4306	1.413e-84	292.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,4CRU1@84995|Rubrobacteria	84995|Rubrobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR21617310_k127_1306748_9	1380390.JIAT01000010_gene4305	1.838e-34	145.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR21617310_k127_1306748_0	58123.JOFJ01000004_gene1825	1.43e-180	581.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4EGVU@85012|Streptosporangiales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR21617310_k127_1306748_10	1068978.AMETH_4861	2.616e-23	107.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4E63H@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR21617310_k127_1306748_2	266117.Rxyl_2662	9.326e-143	465.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR21617310_k127_1306748_8	882083.SacmaDRAFT_4888	6.423e-56	204.0	COG0262@1|root,COG0262@2|Bacteria,2IS3P@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_1306748_7	1127134.NOCYR_1005	7.198e-61	217.0	COG2003@1|root,COG2003@2|Bacteria,2IJG2@201174|Actinobacteria,4FZ7J@85025|Nocardiaceae	201174|Actinobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR21617310_k127_1311513_2	591157.SSLG_04090	1.402e-16	88.0	COG1541@1|root,COG1541@2|Bacteria,2ICK2@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_1311513_0	105425.BBPL01000140_gene4960	1.385e-28	125.0	28N8D@1|root,2ZBCT@2|Bacteria,2GP6B@201174|Actinobacteria,2NM0H@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1311513_1	1349767.GJA_5252	2.329e-27	121.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR21617310_k127_1311622_1	264198.Reut_B5481	1.486e-06	61.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2W004@28216|Betaproteobacteria,1K00Q@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	transporter	-	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
SRR21617310_k127_1311622_0	543632.JOJL01000030_gene3436	3.371e-37	149.0	2F7YJ@1|root,340CE@2|Bacteria,2IIZF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1312600_3	1440053.JOEI01000005_gene2166	2.096e-24	108.0	2E26J@1|root,32XD0@2|Bacteria,2I8EP@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
SRR21617310_k127_1312600_7	1394178.AWOO02000029_gene4629	4.037e-08	61.0	2E26J@1|root,32XD0@2|Bacteria,2I8EP@201174|Actinobacteria,4EFTA@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
SRR21617310_k127_1312600_5	644283.Micau_0295	2.593e-15	79.0	2BJI9@1|root,32DV9@2|Bacteria,2GSZ7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
SRR21617310_k127_1312600_4	1120948.KB903247_gene4647	1.676e-15	82.0	2E73E@1|root,33X4K@2|Bacteria,2GV9A@201174|Actinobacteria,4E7YP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1312600_2	1123023.JIAI01000002_gene5782	5.44e-43	162.0	2DW48@1|root,33YG2@2|Bacteria,2GXC6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1312600_1	1123023.JIAI01000002_gene5783	4.654e-45	169.0	COG0640@1|root,COG0640@2|Bacteria,2I2TF@201174|Actinobacteria,4E7CK@85010|Pseudonocardiales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR21617310_k127_1312600_6	262316.MAP_3678	3.968e-15	79.0	COG0346@1|root,COG0346@2|Bacteria,2ISP0@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR21617310_k127_1312600_0	42256.RradSPS_1185	1.852e-70	242.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria	201174|Actinobacteria	V	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR21617310_k127_1312600_8	882086.SacxiDRAFT_3762	3.766e-05	55.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DY80@85010|Pseudonocardiales	201174|Actinobacteria	P	overlaps another CDS with the same product name	ceoC1	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR21617310_k127_1318010_5	1229780.BN381_130026	7.169e-06	55.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR21617310_k127_1318010_3	469383.Cwoe_1249	7.496e-70	245.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,4CT12@84995|Rubrobacteria	201174|Actinobacteria	K	regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR21617310_k127_1318010_2	1068978.AMETH_2839	3.984e-72	252.0	COG1414@1|root,COG1414@2|Bacteria,2IKWM@201174|Actinobacteria,4E9R5@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR21617310_k127_1318010_4	471857.Svir_26800	7.481e-26	113.0	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria,4E311@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1318010_0	457429.ABJI02000725_gene4008	1.671e-75	265.0	COG0412@1|root,COG0412@2|Bacteria,2I37P@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR21617310_k127_1318010_1	1380370.JIBA01000012_gene3513	7.671e-74	261.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,4FFCA@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR21617310_k127_1322741_2	467200.ACFA01000873_gene4334	3.427e-33	130.0	COG0500@1|root,COG2226@2|Bacteria,2GKH6@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_1322741_1	485913.Krac_3174	2.277e-48	179.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
SRR21617310_k127_1322741_4	883066.HMPREF9233_00893	8.427e-12	71.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4D3Q7@85005|Actinomycetales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_1322741_3	1122138.AQUZ01000016_gene287	1.139e-17	85.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria,4DSMZ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23
SRR21617310_k127_1322741_0	446466.Cfla_0615	6.344e-90	319.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria	201174|Actinobacteria	L	Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_1322741_6	272630.MexAM1_META1p2769	7.54e-05	52.0	COG0785@1|root,COG0785@2|Bacteria,1RBAA@1224|Proteobacteria,2U6KU@28211|Alphaproteobacteria,1JXB9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein	mauF	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1322741_5	1437824.BN940_17496	2.413e-06	56.0	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria,2VQKN@28216|Betaproteobacteria,3T2TU@506|Alcaligenaceae	28216|Betaproteobacteria	CO	Methylamine dehydrogenase accessory protein MauD	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
SRR21617310_k127_1325338_0	1137269.AZWL01000008_gene4630	0.0	1320.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria	201174|Actinobacteria	H	cobaltochelatase CobN subunit	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
SRR21617310_k127_1325338_2	66874.JOFS01000003_gene7168	5.218e-210	689.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2GN3S@201174|Actinobacteria	201174|Actinobacteria	H	von Willebrand factor type A	chlI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
SRR21617310_k127_1325338_7	266117.Rxyl_0637	1.345e-89	310.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4CPY8@84995|Rubrobacteria	84995|Rubrobacteria	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR21617310_k127_1325338_3	266117.Rxyl_0638	1.985e-165	544.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria,4CPJ6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
SRR21617310_k127_1325338_9	929712.KI912613_gene257	1.551e-73	257.0	COG2243@1|root,COG2243@2|Bacteria,2GUI0@201174|Actinobacteria,4CPYP@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR21617310_k127_1325338_6	266117.Rxyl_0640	8.281e-93	321.0	COG2875@1|root,COG2875@2|Bacteria,2GJ97@201174|Actinobacteria,4CPEM@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR21617310_k127_1325338_4	266117.Rxyl_0641	1.067e-139	463.0	COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria,4CPGG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
SRR21617310_k127_1325338_5	266117.Rxyl_0642	1.377e-121	410.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4CPF4@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,PrmA,TP_methylase
SRR21617310_k127_1325338_1	266117.Rxyl_0643	1.39e-211	690.0	COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,2GMIR@201174|Actinobacteria,4CQ4T@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131,3.7.1.12	ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid,TP_methylase
SRR21617310_k127_1325338_8	266117.Rxyl_0646	6.751e-88	309.0	COG2138@1|root,COG2138@2|Bacteria,2GS51@201174|Actinobacteria,4CU1K@84995|Rubrobacteria	84995|Rubrobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR21617310_k127_1333217_1	1122138.AQUZ01000039_gene8045	1.204e-147	479.0	COG4974@1|root,COG4974@2|Bacteria,2IGA2@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1333217_2	1229780.BN381_280002	9.099e-120	396.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1333217_0	1122138.AQUZ01000039_gene8043	1.095e-154	495.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1333217_3	1122138.AQUZ01000039_gene8046	2.135e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4DTJE@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_133439_6	483219.LILAB_00125	5.876e-27	125.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR21617310_k127_133439_2	1304865.JAGF01000001_gene2446	9.662e-87	294.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_133439_3	1869.MB27_30450	8.713e-45	175.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR21617310_k127_133439_5	882083.SacmaDRAFT_3965	1.737e-37	147.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E6RZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR21617310_k127_133439_4	284031.JNXD01000003_gene3748	2.477e-44	172.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_133439_0	595460.RRSWK_03756	1.086e-93	323.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR21617310_k127_133439_7	330214.NIDE3855	2.747e-14	78.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR21617310_k127_133439_1	1288494.EBAPG3_2190	1.573e-88	296.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,3725Z@32003|Nitrosomonadales	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR21617310_k127_1336817_4	543632.JOJL01000119_gene275	2.642e-36	153.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR21617310_k127_1336817_3	43759.JNWK01000118_gene2116	8.928e-61	218.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR21617310_k127_1336817_0	1348338.ADILRU_2235	8.076e-132	432.0	COG4974@1|root,COG4974@2|Bacteria,2IGA2@201174|Actinobacteria,4FRWK@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1336817_1	1348338.ADILRU_2234	2.754e-115	378.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4FSEA@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1336817_2	543632.JOJL01000097_gene5165	1.098e-112	375.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1345603_0	448385.sce8560	0.0	1041.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2YYWN@29|Myxococcales	28221|Deltaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SRR21617310_k127_1346504_2	485913.Krac_2592	2.129e-137	448.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1346504_1	1449976.KALB_7731	2.648e-186	598.0	COG3525@1|root,COG3525@2|Bacteria,2H28J@201174|Actinobacteria,4DYKQ@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CBM_6,Glyco_hydro_20,Glyco_hydro_20b
SRR21617310_k127_1346504_4	105420.BBPO01000007_gene2439	2.348e-73	252.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,2NGB5@228398|Streptacidiphilus	201174|Actinobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR21617310_k127_1346504_0	309801.trd_1067	3.011e-254	803.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,27XPW@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR21617310_k127_1346504_6	1396418.BATQ01000075_gene680	2.275e-20	105.0	COG0438@1|root,COG0438@2|Bacteria,46U6V@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1346504_3	653045.Strvi_4788	1.349e-85	295.0	COG0179@1|root,COG0179@2|Bacteria,2GMSJ@201174|Actinobacteria	201174|Actinobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR21617310_k127_1349896_2	1463825.JNXC01000003_gene3912	4.201e-42	165.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria,4E1X0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR21617310_k127_1349896_1	682795.AciX8_4455	5.351e-45	176.0	2DTT8@1|root,32UVV@2|Bacteria,3Y74Z@57723|Acidobacteria,2JM99@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1349896_0	1370121.AUWS01000062_gene3896	2.244e-89	318.0	COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR21617310_k127_1350656_5	675635.Psed_2104	0.0003061	43.0	COG0685@1|root,COG0685@2|Bacteria,2GJ6U@201174|Actinobacteria,4E9VR@85010|Pseudonocardiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR21617310_k127_1350656_3	644966.Tmar_1299	2.34e-124	409.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR21617310_k127_1350656_1	1303518.CCALI_00259	7.905e-168	536.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR21617310_k127_1350656_2	222534.KB893748_gene2766	4.21e-128	418.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4ESBM@85013|Frankiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR21617310_k127_1350656_4	1003195.SCAT_2743	8.091e-51	194.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR21617310_k127_1350656_0	351607.Acel_1394	0.0	1331.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR21617310_k127_1365211_2	1210884.HG799465_gene11870	3.571e-16	81.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR21617310_k127_1365211_3	1123508.JH636442_gene4266	4.024e-07	52.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR21617310_k127_1365211_6	365528.KB891203_gene3357	5.745e-05	53.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_1365211_4	240015.ACP_2407	6.348e-07	61.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR21617310_k127_1365211_5	1306990.BARG01000033_gene3799	3.541e-06	59.0	2BHEB@1|root,32BGC@2|Bacteria,2GTIS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1365211_1	103733.JNYO01000004_gene7553	1.573e-46	177.0	COG0454@1|root,COG0456@2|Bacteria,2IIN6@201174|Actinobacteria,4E76S@85010|Pseudonocardiales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_1365211_0	35754.JNYJ01000021_gene493	1.631e-47	177.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DGUJ@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR21617310_k127_1373405_5	390989.JOEG01000007_gene596	1.454e-11	68.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR21617310_k127_1373405_2	1122247.C731_2102	1.38e-55	205.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,233YW@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR21617310_k127_1373405_0	196162.Noca_2443	2.42e-79	292.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4DP4E@85009|Propionibacteriales	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR21617310_k127_1373405_1	471852.Tcur_3000	2.506e-76	267.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4EHUK@85012|Streptosporangiales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR21617310_k127_1373405_3	42256.RradSPS_1475	6.265e-43	163.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CQ1V@84995|Rubrobacteria	84995|Rubrobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR21617310_k127_1373405_4	28042.GU90_06205	8.764e-19	95.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4E00W@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR21617310_k127_1380661_0	227882.SAV_670	5.898e-179	570.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	insA	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_1391390_6	926550.CLDAP_33480	7.514e-20	104.0	COG1657@1|root,COG1657@2|Bacteria,2G8NR@200795|Chloroflexi	200795|Chloroflexi	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
SRR21617310_k127_1391390_0	1123023.JIAI01000001_gene6502	1.298e-189	603.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DX7K@85010|Pseudonocardiales	201174|Actinobacteria	E	Alanine dehydrogenase/PNT, C-terminal domain	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,AlaDh_PNT_C
SRR21617310_k127_1391390_1	1122611.KB903947_gene933	2.391e-170	550.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4EHP0@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR21617310_k127_1391390_2	1907.SGLAU_27220	4.303e-124	412.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR21617310_k127_1391390_4	479434.Sthe_2638	1.293e-40	160.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi,27Z83@189775|Thermomicrobia	189775|Thermomicrobia	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR21617310_k127_1391390_3	1463857.JOFZ01000012_gene1720	1.379e-46	175.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR21617310_k127_1391390_7	58123.JOFJ01000001_gene3185	2.533e-18	86.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4EK4Z@85012|Streptosporangiales	201174|Actinobacteria	O	Sulfurtransferase TusA	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR21617310_k127_1391390_5	710111.FraQA3DRAFT_6403	2.731e-24	104.0	COG1104@1|root,COG1104@2|Bacteria,2GJ2B@201174|Actinobacteria,4EU9Z@85013|Frankiales	201174|Actinobacteria	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,TusA
SRR21617310_k127_1396654_4	1089545.KB913037_gene4736	2.55e-13	71.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4E8AR@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1396654_1	465541.ATCJ01000005_gene882	8.554e-86	289.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR21617310_k127_1396654_0	525368.HMPREF0591_0129	1.601e-123	404.0	COG4974@1|root,COG4974@2|Bacteria,2GN10@201174|Actinobacteria,23FBC@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1396654_5	479432.Sros_0166	3.555e-08	61.0	COG4974@1|root,COG4974@2|Bacteria,2GK8T@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1396654_2	1151118.KB895801_gene57	2.42e-26	109.0	2E3V5@1|root,32YSE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23
SRR21617310_k127_1396654_3	749927.AMED_1785	1.313e-17	89.0	2DF7H@1|root,2ZQS3@2|Bacteria,2I5VW@201174|Actinobacteria	201174|Actinobacteria	S	Clp amino terminal domain, pathogenicity island component	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR21617310_k127_1400228_1	1121877.JQKF01000034_gene1989	4.846e-47	178.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_1400228_0	1382306.JNIM01000001_gene1714	6.984e-132	430.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_1400228_2	767029.HMPREF9154_2258	7.383e-13	74.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4DNM4@85009|Propionibacteriales	201174|Actinobacteria	U	Type IV secretory pathway VirD4	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
SRR21617310_k127_1401820_5	479435.Kfla_5999	2.765e-94	325.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQRB@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR21617310_k127_1401820_6	1996.JOFO01000025_gene4356	7.07e-80	290.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4EG6G@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
SRR21617310_k127_1401820_12	465541.ATCJ01000005_gene7105	6.053e-27	113.0	COG1917@1|root,COG1917@2|Bacteria,2IGQV@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1401820_8	1463926.JOCA01000030_gene58	7.673e-55	205.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1401820_7	1348663.KCH_12280	3.147e-58	218.0	COG0642@1|root,COG2205@2|Bacteria,2II4F@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR21617310_k127_1401820_9	1298863.AUEP01000016_gene4322	7.58e-40	168.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DQ1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
SRR21617310_k127_1401820_18	1110502.TMO_2809	5.356e-10	73.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,2JPFX@204441|Rhodospirillales	204441|Rhodospirillales	C	cytochrome c oxidase	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR21617310_k127_1401820_0	926564.KI911619_gene3985	5.061e-186	596.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4F3NG@85017|Promicromonosporaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR21617310_k127_1401820_10	1122998.AUHZ01000004_gene1044	3.229e-39	159.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DNSR@85009|Propionibacteriales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR21617310_k127_1401820_19	1211815.CBYP010000006_gene276	3.854e-06	55.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1401820_16	73044.JNXP01000005_gene252	5.18e-20	94.0	2EKJY@1|root,33E9T@2|Bacteria,2IQW9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
SRR21617310_k127_1401820_3	1123024.AUII01000036_gene3156	5.519e-136	442.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria,4E870@85010|Pseudonocardiales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR21617310_k127_1401820_15	1380390.JIAT01000011_gene2362	4.506e-20	97.0	COG0599@1|root,COG0599@2|Bacteria,2HUBM@201174|Actinobacteria,4CU1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1401820_1	1380347.JNII01000005_gene3230	1.464e-179	599.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4ETWF@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR21617310_k127_1401820_14	1116232.AHBF01000103_gene6252	1.116e-21	109.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Ricin_B_lectin
SRR21617310_k127_1401820_11	710111.FraQA3DRAFT_6465	2.389e-35	144.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4ES4W@85013|Frankiales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR21617310_k127_1401820_2	1048339.KB913029_gene1694	6.809e-164	528.0	COG0467@1|root,COG0467@2|Bacteria,2I58C@201174|Actinobacteria	201174|Actinobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR21617310_k127_1401820_13	1089546.AQUI01000002_gene894	4.227e-25	120.0	COG0745@1|root,COG0745@2|Bacteria	1089546.AQUI01000002_gene894|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1401820_17	446466.Cfla_2587	4.473e-11	75.0	COG0789@1|root,COG0789@2|Bacteria,2I8T8@201174|Actinobacteria,4F18K@85016|Cellulomonadaceae	201174|Actinobacteria	K	SMART regulatory protein MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
SRR21617310_k127_1401820_4	1150864.MILUP08_45546	8.535e-126	412.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DAC4@85008|Micromonosporales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR21617310_k127_1401957_6	1463825.JNXC01000034_gene2675	4.65e-63	231.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4DY75@85010|Pseudonocardiales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
SRR21617310_k127_1401957_3	66874.JOFS01000012_gene4832	2.963e-114	376.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR21617310_k127_1401957_11	1123322.KB904652_gene536	4.777e-12	76.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR21617310_k127_1401957_1	1123322.KB904652_gene537	9.949e-121	403.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR21617310_k127_1401957_0	1123322.KB904710_gene87	2.228e-242	759.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR21617310_k127_1401957_7	930171.Asphe3_27290	8.457e-44	162.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,1W9GN@1268|Micrococcaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR21617310_k127_1401957_9	1068978.AMETH_1438	8.007e-29	121.0	COG1846@1|root,COG1846@2|Bacteria,2IJPR@201174|Actinobacteria,4E5J7@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_1401957_2	1120950.KB892743_gene3162	2.584e-118	395.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DTG1@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1401957_4	1003195.SCAT_1895	1.152e-111	368.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_1401957_5	370438.PTH_2656	1.127e-103	349.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,260QV@186807|Peptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR21617310_k127_1401957_8	1313172.YM304_08950	4.751e-38	149.0	COG0454@1|root,COG0456@2|Bacteria,2HGCA@201174|Actinobacteria,4CNAC@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR21617310_k127_1401957_10	1313172.YM304_08940	4.097e-15	80.0	COG1214@1|root,COG1214@2|Bacteria	2|Bacteria	O	tRNA threonylcarbamoyladenosine modification	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR21617310_k127_140424_3	1169161.KB897719_gene3556	3.529e-12	68.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_140424_2	1136417.AZWE01000066_gene1147	2.959e-22	100.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D9V4@85008|Micromonosporales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_140424_0	211114.JOEF01000008_gene1249	7.524e-42	161.0	COG0640@1|root,COG0640@2|Bacteria,2IEHG@201174|Actinobacteria,4E40T@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_140424_1	649831.L083_5569	1.327e-35	141.0	COG2211@1|root,COG2211@2|Bacteria,2HJ1P@201174|Actinobacteria,4D992@85008|Micromonosporales	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_140424_4	1463820.JOGW01000022_gene345	5.51e-05	49.0	COG2211@1|root,COG2211@2|Bacteria,2HJ1P@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
SRR21617310_k127_1415333_3	1068980.ARVW01000001_gene7309	4.444e-74	254.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4E07J@85010|Pseudonocardiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR21617310_k127_1415333_7	1297742.A176_01561	3.975e-28	120.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_1415333_8	91464.S7335_3946	3.41e-20	98.0	COG0776@1|root,COG0776@2|Bacteria,1G7ER@1117|Cyanobacteria,1H0RE@1129|Synechococcus	1117|Cyanobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	himA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR21617310_k127_1415333_10	58123.JOFJ01000003_gene2087	7.574e-05	48.0	COG1920@1|root,COG1920@2|Bacteria,2GQPF@201174|Actinobacteria,4EKJA@85012|Streptosporangiales	201174|Actinobacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1415333_9	1120956.JHZK01000012_gene3638	2.067e-15	88.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2UAA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR21617310_k127_1415333_6	263358.VAB18032_11355	2.916e-43	168.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4DARQ@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR21617310_k127_1415333_1	1449976.KALB_5013	4.127e-130	431.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4E18U@85010|Pseudonocardiales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR21617310_k127_1415333_2	479434.Sthe_1990	2.802e-113	381.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR21617310_k127_1415333_4	269800.Tfu_2876	1.523e-64	233.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4EGP6@85012|Streptosporangiales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_1415333_0	1463845.JOIG01000009_gene3115	3.733e-189	602.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_1415333_5	351607.Acel_0114	9.345e-50	181.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4ERX6@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR21617310_k127_143788_2	1380390.JIAT01000009_gene664	8.043e-51	187.0	COG3832@1|root,COG3832@2|Bacteria,2II8T@201174|Actinobacteria,4CQRH@84995|Rubrobacteria	84995|Rubrobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_143788_0	1123024.AUII01000005_gene2472	5.607e-234	749.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4E2DC@85010|Pseudonocardiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR21617310_k127_143788_4	1123024.AUII01000005_gene2474	6.681e-38	156.0	2AY0G@1|root,31Q21@2|Bacteria,2HS82@201174|Actinobacteria,4ECU1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_143788_3	1122138.AQUZ01000094_gene5494	3.264e-43	160.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR21617310_k127_143788_1	1121877.JQKF01000023_gene2249	4.022e-174	552.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CMSY@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR21617310_k127_1438393_0	469383.Cwoe_3291	4.506e-172	557.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria,4CP7Q@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1438393_8	485913.Krac_2896	8.252e-58	210.0	COG0640@1|root,COG0640@2|Bacteria,2G975@200795|Chloroflexi	200795|Chloroflexi	K	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR21617310_k127_1438393_3	106370.Francci3_0270	3.775e-108	376.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4ERVT@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR21617310_k127_1438393_10	1444306.JFZC01000101_gene1275	1.514e-25	111.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26NYU@186821|Sporolactobacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR21617310_k127_1438393_4	1157637.KB892093_gene6817	5.328e-97	320.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR21617310_k127_1438393_1	1121877.JQKF01000011_gene381	3.082e-155	504.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR21617310_k127_1438393_5	656024.FsymDg_0584	2.564e-85	310.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4ERE4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR21617310_k127_1438393_6	298654.FraEuI1c_1881	4.031e-76	266.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR21617310_k127_1438393_9	1297742.A176_05398	3.484e-38	158.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR21617310_k127_1438393_2	710696.Intca_2005	8.989e-112	379.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4FEK3@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_1438393_7	1157637.KB892095_gene2730	6.092e-69	246.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR21617310_k127_1440227_1	196162.Noca_1954	7.209e-201	634.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
SRR21617310_k127_1440227_3	196162.Noca_1953	6.318e-57	206.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria	201174|Actinobacteria	O	heme exporter protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR21617310_k127_1440227_2	196162.Noca_1952	9.751e-65	228.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR21617310_k127_1440227_5	1033739.CAEU01000031_gene1606	3.876e-06	52.0	COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR21617310_k127_1440227_4	47716.JOFH01000017_gene5231	9.543e-46	174.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2IEKD@201174|Actinobacteria	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_1440227_0	58123.JOFJ01000014_gene5040	1.455e-228	739.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4EI65@85012|Streptosporangiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1441264_3	469371.Tbis_0410	6.732e-16	80.0	COG0517@1|root,COG0517@2|Bacteria,2I3TG@201174|Actinobacteria,4EC77@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_1441264_2	471852.Tcur_0499	2.216e-29	126.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJNW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR21617310_k127_1441264_0	378806.STAUR_1909	2.092e-151	493.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR21617310_k127_1441264_1	1122611.KB903984_gene3917	1.159e-86	292.0	COG1309@1|root,COG1309@2|Bacteria,2IKBM@201174|Actinobacteria,4ENS1@85012|Streptosporangiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1448941_4	1380393.JHVP01000002_gene1934	1.742e-48	178.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR21617310_k127_1448941_0	1394178.AWOO02000001_gene1499	9.127e-234	730.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_1448941_3	326424.FRAAL6835	4.454e-107	355.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4ESYW@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	potI	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR21617310_k127_1448941_2	298655.KI912266_gene1197	7.097e-116	380.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4ET85@85013|Frankiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	potH	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR21617310_k127_1448941_1	298654.FraEuI1c_0033	4.136e-148	485.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4ESHI@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR21617310_k127_1448941_5	58123.JOFJ01000003_gene2017	4.415e-30	124.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR21617310_k127_1450510_4	298654.FraEuI1c_2442	4.442e-32	128.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_1450510_2	298654.FraEuI1c_4452	2.848e-79	285.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR21617310_k127_1450510_3	28072.Nos7524_2690	5.771e-71	247.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR21617310_k127_1450510_1	469383.Cwoe_2922	1.149e-132	444.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_1450510_0	1122182.KB903834_gene5922	1.075e-144	490.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D9UJ@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_1455685_1	479432.Sros_4184	2.37e-128	419.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ENIC@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1455685_2	479432.Sros_4183	4.227e-94	315.0	COG0842@1|root,COG0842@2|Bacteria,2IHJH@201174|Actinobacteria,4ENXS@85012|Streptosporangiales	201174|Actinobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_1455685_0	1068978.AMETH_2301	4.533e-151	483.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4DY2W@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR21617310_k127_1455685_4	1449355.JQNR01000005_gene3603	1.773e-20	98.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRR21617310_k127_1455685_3	1122611.KB903959_gene4174	8.725e-53	194.0	2B6QV@1|root,31ZPN@2|Bacteria,2H2FF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1461218_0	1254432.SCE1572_36930	1.282e-209	669.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR21617310_k127_1461218_3	46234.ANA_C12164	2.737e-14	80.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1HN52@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR21617310_k127_1461218_2	525909.Afer_1115	4.766e-16	84.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1461218_1	1169161.KB897716_gene5815	4.561e-50	185.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_1462981_1	390989.JOEG01000005_gene1969	1.066e-65	230.0	COG1994@1|root,COG1994@2|Bacteria,2I9PV@201174|Actinobacteria,4DDWQ@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1462981_3	390989.JOEG01000005_gene1968	2.984e-53	203.0	2DDJY@1|root,32U1P@2|Bacteria,2H1DV@201174|Actinobacteria,4DGCZ@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR21617310_k127_1462981_0	591157.SSLG_04090	5.69e-113	381.0	COG1541@1|root,COG1541@2|Bacteria,2ICK2@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_1462981_4	105425.BBPL01000098_gene1244	1.356e-46	183.0	2AJVX@1|root,31AIP@2|Bacteria,2GJIY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1462981_9	525904.Tter_2098	1.694e-30	141.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR21617310_k127_1462981_2	251221.35213566	6.376e-58	231.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1462981_8	710111.FraQA3DRAFT_2475	2.506e-37	145.0	COG2319@1|root,COG3316@1|root,COG2319@2|Bacteria,COG3316@2|Bacteria,2H0HI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_1462981_11	543632.JOJL01000016_gene8762	1.219e-10	64.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_1462981_12	298653.Franean1_2850	3.494e-09	63.0	COG3316@1|root,COG3316@2|Bacteria,2H0HI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_1462981_10	471852.Tcur_4370	1.993e-12	73.0	COG3920@1|root,COG3920@2|Bacteria,2I4IA@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR21617310_k127_1462981_15	656024.FsymDg_2940	6.608e-05	51.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria,4EVXY@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR21617310_k127_1462981_14	1382306.JNIM01000001_gene4018	5.401e-05	46.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8
SRR21617310_k127_1462981_5	1382306.JNIM01000001_gene4018	2.807e-45	175.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8
SRR21617310_k127_1462981_6	68570.DC74_502	1.345e-39	158.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1462981_7	1394178.AWOO02000076_gene1961	4.509e-39	158.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_1462981_13	1394178.AWOO02000076_gene1961	4.094e-07	57.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_1470616_0	566461.SSFG_07526	4.096e-145	463.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR21617310_k127_1470616_1	285535.JOEY01000062_gene9977	7.02e-127	411.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR21617310_k127_1479995_2	309801.trd_0162	1.428e-52	196.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia	189775|Thermomicrobia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR21617310_k127_1479995_4	219305.MCAG_04943	2.355e-40	153.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4DE1B@85008|Micromonosporales	201174|Actinobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_1479995_0	2002.JOEQ01000004_gene2761	8.75e-88	296.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EI7I@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1479995_1	67275.JOAP01000029_gene5506	1.924e-56	204.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR21617310_k127_1479995_3	1179773.BN6_10300	2.745e-46	183.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4DZVK@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR21617310_k127_1481068_4	369723.Strop_3800	3.601e-41	164.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4D8FI@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_1481068_0	318424.EU78_01995	4.448e-108	375.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,233DE@1762|Mycobacteriaceae	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_1481068_1	1121377.KB906409_gene867	2.8e-82	284.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_01210	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR21617310_k127_1481068_3	1121377.KB906409_gene866	3.568e-72	256.0	COG0601@1|root,COG0601@2|Bacteria,1WIUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR21617310_k127_1481068_2	330084.JNYZ01000044_gene1993	5.091e-79	285.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4E5IK@85010|Pseudonocardiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_1485260_2	1304865.JAGF01000001_gene3360	5.736e-19	89.0	COG0695@1|root,COG0695@2|Bacteria,2GS68@201174|Actinobacteria	201174|Actinobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR21617310_k127_1485260_0	196162.Noca_3784	5.22e-137	444.0	COG0785@1|root,COG0785@2|Bacteria,2GMXW@201174|Actinobacteria,4DTAU@85009|Propionibacteriales	201174|Actinobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR21617310_k127_1485260_1	1171373.PACID_01680	3.07e-51	203.0	COG1225@1|root,COG1225@2|Bacteria,2IGFI@201174|Actinobacteria,4DRG7@85009|Propionibacteriales	201174|Actinobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR21617310_k127_1487154_2	1120934.KB894425_gene1176	1.513e-47	179.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DX7I@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1487154_4	1449976.KALB_5093	4.078e-17	95.0	COG3903@1|root,COG3903@2|Bacteria,2H5B5@201174|Actinobacteria,4EDW1@85010|Pseudonocardiales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
SRR21617310_k127_1487154_1	43354.JOIJ01000015_gene1259	7.831e-69	246.0	COG3570@1|root,COG3570@2|Bacteria,2ICQG@201174|Actinobacteria,4E3VE@85010|Pseudonocardiales	201174|Actinobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRR21617310_k127_1487154_0	1089544.KB912942_gene1881	3.61e-199	642.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR21617310_k127_1487154_5	882083.SacmaDRAFT_3107	1.406e-06	57.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR21617310_k127_1493076_0	1120949.KB903294_gene4280	1.965e-212	696.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR21617310_k127_1493076_2	1042326.AZNV01000001_gene5361	1.355e-104	353.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2VFJH@28211|Alphaproteobacteria,4BNA2@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1493076_16	66377.JOBH01000012_gene4401	2.077e-05	52.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_1493076_7	1121272.KB903283_gene4936	1.301e-35	141.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1493076_1	1121272.KB903283_gene4936	4.905e-146	469.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_1493076_8	1267533.KB906733_gene3125	1.532e-27	119.0	COG0702@1|root,COG0702@2|Bacteria,3Y3QX@57723|Acidobacteria,2JJ6V@204432|Acidobacteriia	204432|Acidobacteriia	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR21617310_k127_1493076_15	682795.AciX8_0239	1.734e-05	49.0	COG0702@1|root,COG0702@2|Bacteria,3Y3QX@57723|Acidobacteria,2JJ6V@204432|Acidobacteriia	204432|Acidobacteriia	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR21617310_k127_1493076_12	359.CN09_19735	2.635e-15	77.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,4B8Q9@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_1493076_14	1500301.JQMF01000008_gene1095	9.767e-11	73.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,4B8Q9@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_1493076_11	1185876.BN8_04702	6.209e-16	81.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
SRR21617310_k127_1493076_9	1532557.JL37_21095	3.389e-23	100.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2VN2W@28216|Betaproteobacteria,3T8Z0@506|Alcaligenaceae	28216|Betaproteobacteria	I	Prolyl oligopeptidase family	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_1493076_3	83332.Rv1190	1.292e-99	336.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23610@1762|Mycobacteriaceae	201174|Actinobacteria	S	Haloalkane dehalogenase	dhmA2	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_1493076_10	931627.MycrhDRAFT_0222	1.033e-16	88.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria,23AE5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_1493076_5	222534.KB893694_gene86	6.619e-81	277.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR21617310_k127_1493076_4	1123023.JIAI01000001_gene7656	4.487e-88	310.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1493076_6	1218084.BBJK01000031_gene2960	1.846e-52	205.0	COG2128@1|root,COG2128@2|Bacteria,1PIG7@1224|Proteobacteria,2W72Z@28216|Betaproteobacteria,1KDND@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1493076_13	1122138.AQUZ01000002_gene2132	4.978e-13	69.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
SRR21617310_k127_1511317_0	1394178.AWOO02000064_gene77	2.155e-109	361.0	28P5T@1|root,2ZC0N@2|Bacteria,2GP34@201174|Actinobacteria,4EGR1@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1511317_4	1120950.KB892770_gene1361	4.856e-09	58.0	2CIG4@1|root,33C84@2|Bacteria,2GWMV@201174|Actinobacteria,4DSVI@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1511317_1	1961.JOAK01000060_gene3638	3.032e-102	342.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR21617310_k127_1511317_2	469383.Cwoe_5336	3.099e-62	223.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CQJI@84995|Rubrobacteria	84995|Rubrobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR21617310_k127_1511317_3	309801.trd_A0246	1.287e-29	119.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Auxin_BP,Cupin_2
SRR21617310_k127_152240_1	1206737.BAGF01000045_gene2802	1.567e-127	416.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4FW8F@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_152240_3	298655.KI912267_gene6908	1.68e-72	256.0	COG1846@1|root,COG1846@2|Bacteria,2IQQ8@201174|Actinobacteria	201174|Actinobacteria	K	marr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
SRR21617310_k127_152240_2	479432.Sros_6513	1.499e-91	317.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4EQ0V@85012|Streptosporangiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
SRR21617310_k127_152240_4	1206731.BAGB01000174_gene2003	1.47e-47	174.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4G0FQ@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR21617310_k127_152240_5	1168034.FH5T_09445	1.845e-31	128.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,2FSKU@200643|Bacteroidia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR21617310_k127_152240_0	479434.Sthe_2889	6.468e-220	704.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinaseoxoprolinase domain protein	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR21617310_k127_152240_6	189753.AXAS01000001_gene3670	7.074e-11	66.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,3JUF2@41294|Bradyrhizobiaceae	1224|Proteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR21617310_k127_1523205_2	1463841.JOIR01000023_gene512	1.595e-86	323.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR21617310_k127_1523205_4	1121363.KB902185_gene328	7.299e-30	121.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,22NJY@1653|Corynebacteriaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR21617310_k127_1523205_5	1120950.KB892759_gene6283	8.307e-20	89.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4DPEA@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR21617310_k127_1523205_3	1120950.KB892759_gene6283	1.699e-73	255.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4DPEA@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR21617310_k127_1523205_1	326424.FRAAL1259	3.565e-117	402.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4ERHZ@85013|Frankiales	201174|Actinobacteria	C	F420-dependent oxidoreductase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR21617310_k127_1523205_0	1343740.M271_36895	3.702e-146	481.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria	201174|Actinobacteria	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR21617310_k127_1523862_0	649831.L083_5257	2.135e-29	136.0	COG3170@1|root,COG3170@2|Bacteria,2I3VQ@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1523862_4	639282.DEFDS_2074	3.745e-05	46.0	COG0365@1|root,COG0365@2|Bacteria,2GF81@200930|Deferribacteres	200930|Deferribacteres	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1523862_2	555088.DealDRAFT_2031	5.028e-12	68.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,25AZ5@186801|Clostridia	186801|Clostridia	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1,6.2.1.2	ko:K01895,ko:K01896	ko00010,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01176,R01354	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1523862_1	643562.Daes_0542	6.128e-27	113.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2M8EP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1535227_16	42256.RradSPS_2624	2.822e-32	128.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CSQX@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_1535227_6	1382356.JQMP01000004_gene230	5.386e-96	328.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,27Y33@189775|Thermomicrobia	189775|Thermomicrobia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR21617310_k127_1535227_8	1068978.AMETH_1119	7.762e-85	298.0	COG3552@1|root,COG3552@2|Bacteria,2IGRI@201174|Actinobacteria,4E91Q@85010|Pseudonocardiales	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR21617310_k127_1535227_15	1122179.KB890433_gene4030	2.711e-33	134.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1IUNA@117747|Sphingobacteriia	976|Bacteroidetes	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR21617310_k127_1535227_5	469371.Tbis_1947	1.53e-107	359.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4DXVJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR21617310_k127_1535227_12	710111.FraQA3DRAFT_1741	1.799e-58	205.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4ESRX@85013|Frankiales	201174|Actinobacteria	O	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR21617310_k127_1535227_17	1120950.KB892708_gene4261	1.812e-31	129.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4DRZV@85009|Propionibacteriales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR21617310_k127_1535227_14	101510.RHA1_ro02769	2.83e-47	179.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4G1UD@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1535227_21	404380.Gbem_2013	8.269e-11	74.0	2DQJB@1|root,3377V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1535227_22	330214.NIDE2528	1.054e-10	70.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR21617310_k127_1535227_3	58123.JOFJ01000001_gene3199	6.748e-116	391.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4EHZN@85012|Streptosporangiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR21617310_k127_1535227_1	1120936.KB907214_gene4250	1.133e-139	455.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4EHXK@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase dimerisation domain	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR21617310_k127_1535227_7	1449355.JQNR01000005_gene4162	4.423e-88	314.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria	201174|Actinobacteria	G	inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR21617310_k127_1535227_10	471852.Tcur_0131	1.343e-72	250.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4EIVP@85012|Streptosporangiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR21617310_k127_1535227_9	1120950.KB892707_gene4943	9.982e-75	261.0	COG3402@1|root,COG3402@2|Bacteria,2IQFA@201174|Actinobacteria,4DRVU@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR21617310_k127_1535227_0	1120950.KB892707_gene4942	5.862e-179	586.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4DNHT@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR21617310_k127_1535227_24	1229780.BN381_210111	7.029e-05	56.0	2C8AG@1|root,33SQR@2|Bacteria,2H3BF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1535227_20	1335760.ASTG01000019_gene2712	1.119e-17	95.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1535227_13	345341.KUTG_04248	3.695e-52	201.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4E04Q@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR21617310_k127_1535227_19	1206732.BAGD01000097_gene4107	2.809e-20	101.0	COG0589@1|root,COG0589@2|Bacteria,2IP0V@201174|Actinobacteria,4G2VZ@85025|Nocardiaceae	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR21617310_k127_1535227_23	1158762.KB898037_gene2208	1.306e-08	65.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR21617310_k127_1535227_2	471852.Tcur_1188	3.509e-131	428.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4EHYM@85012|Streptosporangiales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR21617310_k127_1535227_4	1157632.AQWQ01000012_gene2573	1.181e-112	383.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR21617310_k127_1535227_11	1229780.BN381_130137	4.034e-70	248.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR21617310_k127_1535227_18	1122622.ATWJ01000002_gene795	5.215e-30	124.0	COG1733@1|root,COG1733@2|Bacteria,2IRHS@201174|Actinobacteria,4FI6I@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_1535227_25	1463926.JOCA01000030_gene92	0.0008731	44.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR21617310_k127_1536071_0	351607.Acel_0975	8.122e-71	255.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4EVMD@85013|Frankiales	201174|Actinobacteria	D	Evidence 2b Function of strongly homologous gene	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRR21617310_k127_1536071_3	926569.ANT_31220	6.91e-25	118.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR21617310_k127_1536071_1	1172179.AUKV01000014_gene3612	9.432e-53	194.0	COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1536071_5	251221.35214735	3.037e-21	104.0	COG0642@1|root,COG2205@2|Bacteria,1G113@1117|Cyanobacteria	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1536071_4	68199.JNZO01000001_gene985	2.202e-21	107.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR21617310_k127_1536071_2	526225.Gobs_3194	1.797e-47	178.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4ESQB@85013|Frankiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_1536071_6	1120945.ATUW01000005_gene623	3.931e-09	61.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_8	1463856.JOHY01000007_gene766	1.14e-08	63.0	2B582@1|root,31Y1Z@2|Bacteria,2H02P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_0	67267.JNXT01000054_gene2986	8.165e-101	339.0	2F09Z@1|root,33TD7@2|Bacteria,2IAJA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_7	68219.JNXI01000003_gene4905	9.617e-10	66.0	29000@1|root,2ZMQA@2|Bacteria,2GW58@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_3	1463900.JOIX01000006_gene748	4.686e-43	167.0	2FB21@1|root,3438R@2|Bacteria,2IMEA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_1	1463900.JOIX01000006_gene749	5.429e-77	265.0	2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_5	711393.AYRX01000095_gene3553	8.296e-37	146.0	29AFZ@1|root,2ZXG6@2|Bacteria,2IJWT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_2	68219.JNXI01000003_gene4900	5.467e-55	200.0	2FATI@1|root,3430S@2|Bacteria,2IK0E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_9	1463900.JOIX01000006_gene752	1.621e-06	58.0	28T1Y@1|root,2ZFB6@2|Bacteria,2GY0G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_6	1122138.AQUZ01000004_gene1037	5.093e-20	102.0	COG5412@1|root,COG5412@2|Bacteria	2|Bacteria	N	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1537995_4	1121272.KB903293_gene7149	1.516e-41	156.0	2BMI5@1|root,32G32@2|Bacteria,2H1B8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1540348_7	526225.Gobs_3529	1.534e-10	61.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria,4EXAV@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1540348_2	526225.Gobs_3529	1.622e-100	336.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria,4EXAV@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1540348_3	1268072.PSAB_13200	9.678e-77	262.0	COG0262@1|root,COG0262@2|Bacteria,1TTIM@1239|Firmicutes,4IE55@91061|Bacilli,26ZS2@186822|Paenibacillaceae	91061|Bacilli	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_1540348_6	390989.JOEG01000014_gene3137	3.615e-13	72.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR21617310_k127_1540348_5	1123060.JONP01000051_gene879	7.798e-16	89.0	COG3547@1|root,COG3547@2|Bacteria,1QPKD@1224|Proteobacteria,2TUIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1540348_4	1136417.AZWE01000066_gene1147	9.902e-29	120.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D9V4@85008|Micromonosporales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1540348_8	1136417.AZWE01000066_gene1147	1.877e-05	56.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D9V4@85008|Micromonosporales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1540348_1	1463856.JOHY01000035_gene1868	3.387e-135	452.0	COG3209@1|root,COG3271@1|root,COG3209@2|Bacteria,COG3271@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PT-HINT,RHS_repeat,VCBS
SRR21617310_k127_1540348_0	1463825.JNXC01000054_gene1095	1.192e-194	629.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4E2E3@85010|Pseudonocardiales	201174|Actinobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
SRR21617310_k127_1540810_0	861299.J421_4433	1.784e-184	593.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1540810_1	929712.KI912613_gene2650	6.355e-05	52.0	COG1309@1|root,COG1309@2|Bacteria,2HQ9V@201174|Actinobacteria,4CRTR@84995|Rubrobacteria	84995|Rubrobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR21617310_k127_154155_6	1429046.RR21198_4450	2.594e-36	146.0	2EC8S@1|root,33677@2|Bacteria,2GUT2@201174|Actinobacteria,4G3D7@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_154155_1	479432.Sros_7134	4.586e-190	615.0	COG3325@1|root,COG3325@2|Bacteria,2GJGW@201174|Actinobacteria,4EGAJ@85012|Streptosporangiales	201174|Actinobacteria	G	Glyco_18	chiC2	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
SRR21617310_k127_154155_7	345341.KUTG_06662	1.814e-24	105.0	COG2161@1|root,COG2161@2|Bacteria,2GZJV@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR21617310_k127_154155_3	345341.KUTG_06661	4.192e-51	184.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4E7ES@85010|Pseudonocardiales	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR21617310_k127_154155_0	1120949.KB903328_gene9050	8.782e-243	779.0	COG4995@1|root,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DBR2@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR21617310_k127_154155_4	1120949.KB903328_gene9049	1.728e-47	178.0	2E27K@1|root,32XDT@2|Bacteria,2GRMM@201174|Actinobacteria,4DFZH@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_154155_2	1120949.KB903328_gene9048	2.539e-78	266.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4DF59@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR21617310_k127_154155_5	1120949.KB903328_gene9047	2.453e-39	156.0	COG1404@1|root,COG1404@2|Bacteria,2HURQ@201174|Actinobacteria,4DFXH@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR21617310_k127_1550953_6	1223544.GSI01S_30_00010	9.561e-09	66.0	COG0791@1|root,COG0791@2|Bacteria,2IIW8@201174|Actinobacteria	201174|Actinobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR21617310_k127_1550953_3	882082.SaccyDRAFT_3252	1.022e-119	411.0	COG4225@1|root,COG4225@2|Bacteria,2I78E@201174|Actinobacteria	201174|Actinobacteria	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
SRR21617310_k127_1550953_5	1382358.JHVN01000002_gene2328	3.484e-30	139.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,4HAGD@91061|Bacilli	91061|Bacilli	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR21617310_k127_1550953_4	710111.FraQA3DRAFT_4730	1.095e-90	309.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR21617310_k127_1550953_2	469383.Cwoe_5400	3.057e-133	437.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CPCS@84995|Rubrobacteria	84995|Rubrobacteria	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR21617310_k127_1550953_1	351607.Acel_0283	5.655e-155	516.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4ERDE@85013|Frankiales	201174|Actinobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR21617310_k127_1550953_0	1449347.JQLN01000005_gene3995	3.973e-309	960.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,2M0RC@2063|Kitasatospora	201174|Actinobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR21617310_k127_1554313_3	1463864.JOGO01000007_gene630	1.614e-113	380.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR21617310_k127_1554313_4	298655.KI912266_gene6518	2.037e-103	342.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria,4ES2J@85013|Frankiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1554313_0	1380356.JNIK01000013_gene4321	1.14e-294	913.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR21617310_k127_1554313_2	196162.Noca_3547	3.926e-128	413.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DNTD@85009|Propionibacteriales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR21617310_k127_1554313_6	469383.Cwoe_3269	2.175e-54	203.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR21617310_k127_1554313_8	1223544.GSI01S_04_00130	2.328e-53	198.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4GA6K@85026|Gordoniaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR21617310_k127_1554313_10	319795.Dgeo_1964	6.697e-06	56.0	COG1826@1|root,COG1826@2|Bacteria,1WKJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR21617310_k127_1554313_7	1121017.AUFG01000035_gene715	2.593e-54	203.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4FEBU@85021|Intrasporangiaceae	201174|Actinobacteria	K	Proteasome accessory factor C	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR21617310_k127_1554313_9	479432.Sros_5862	9.61e-47	180.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4EFRP@85012|Streptosporangiales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR21617310_k127_1554313_11	1123322.KB904684_gene4817	7.745e-05	55.0	28XM2@1|root,2ZJI4@2|Bacteria,2HBAV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1554313_1	479432.Sros_7396	1.19e-131	431.0	COG0204@1|root,COG0204@2|Bacteria,2I8I4@201174|Actinobacteria,4EFXH@85012|Streptosporangiales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR21617310_k127_1554313_5	479432.Sros_7395	4.789e-93	309.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4EHBT@85012|Streptosporangiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR21617310_k127_1560825_0	285535.JOEY01000106_gene3959	1.738e-129	436.0	COG0582@1|root,COG0582@2|Bacteria,2GK5Z@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_4	285535.JOEY01000106_gene3958	1.767e-43	170.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_8	345341.KUTG_09502	2.526e-09	68.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_6	285535.JOEY01000106_gene3958	7.044e-39	162.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_10	1033736.CAHK01000029_gene1342	0.0001078	52.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_2	285535.JOEY01000106_gene3957	6.757e-61	215.0	COG0582@1|root,COG0582@2|Bacteria,2I37T@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1560825_7	272123.Anacy_1018	3.947e-18	87.0	2E1PE@1|root,32WZY@2|Bacteria,1G8BY@1117|Cyanobacteria,1HP3G@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_5	83332.Rv2811	7.432e-41	160.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria,239RI@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1560825_3	543632.JOJL01000132_gene3147	1.774e-55	213.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	2|Bacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,Mu-transpos_C,rve
SRR21617310_k127_1560825_1	436229.JOEH01000054_gene6400	2.001e-90	314.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,2NKFK@228398|Streptacidiphilus	201174|Actinobacteria	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR21617310_k127_1560825_9	479431.Namu_4945	5.061e-08	55.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR21617310_k127_1571070_10	887062.HGR_12432	6.472e-32	145.0	COG1196@1|root,COG1196@2|Bacteria,1NGZ2@1224|Proteobacteria,2VIWY@28216|Betaproteobacteria,4AGAW@80864|Comamonadaceae	28216|Betaproteobacteria	D	SMC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_29,SMC_N
SRR21617310_k127_1571070_2	561175.KB894095_gene2632	1.995e-113	381.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4ER0W@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_1571070_12	1121924.ATWH01000001_gene4469	5.809e-22	101.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4FPSM@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_1571070_7	1385520.N802_08935	4.4e-55	199.0	COG5340@1|root,COG5340@2|Bacteria,2IDWV@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
SRR21617310_k127_1571070_5	467200.ACFA01000629_gene6248	1.612e-76	265.0	2EAM9@1|root,334PX@2|Bacteria,2ID76@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR21617310_k127_1571070_4	1283299.AUKG01000002_gene5072	1.676e-86	305.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1571070_13	1157638.KB892196_gene2767	8.365e-07	59.0	COG4934@1|root,COG4934@2|Bacteria,2IAX1@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1571070_6	861299.J421_3248	3.285e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1571070_0	1382356.JQMP01000004_gene398	1.307e-121	400.0	COG0309@1|root,COG0309@2|Bacteria,2G7TM@200795|Chloroflexi,27XK5@189775|Thermomicrobia	189775|Thermomicrobia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
SRR21617310_k127_1571070_8	1121124.JNIX01000016_gene2057	5.616e-55	209.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2KFMD@204458|Caulobacterales	204458|Caulobacterales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_1571070_9	298654.FraEuI1c_0340	4.877e-51	192.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4ESRH@85013|Frankiales	201174|Actinobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_1571070_3	765420.OSCT_3123	7.753e-109	372.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,376BM@32061|Chloroflexia	32061|Chloroflexia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR21617310_k127_1571070_1	479434.Sthe_1974	3.057e-120	412.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR21617310_k127_1571070_11	1463921.JODF01000078_gene6510	9.365e-30	118.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR21617310_k127_1576666_2	1449044.JMLE01000029_gene106	1.386e-94	332.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1WAY5@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, C-terminal domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_1576666_1	1151119.KB895489_gene649	1.071e-140	474.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_1576666_0	1151119.KB895489_gene650	5.675e-268	839.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1576666_6	1449347.JQLN01000007_gene1817	7.477e-40	165.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,2M4FI@2063|Kitasatospora	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_1576666_5	882083.SacmaDRAFT_3107	1.293e-44	176.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR21617310_k127_1576666_3	298654.FraEuI1c_0845	8.807e-71	258.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRR21617310_k127_1576666_4	316274.Haur_1008	5.241e-50	196.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cornifin,NLPC_P60,SH3_3
SRR21617310_k127_1576666_7	196162.Noca_0285	8.728e-16	84.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR21617310_k127_158019_3	1127134.NOCYR_2871	1.697e-50	183.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4FX3Z@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	tnpAC	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_158019_2	1150864.MILUP08_40242	1.797e-59	208.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4DEGR@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_158019_8	1056816.JAFQ01000004_gene6015	3.307e-08	55.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria,4FZTR@85025|Nocardiaceae	201174|Actinobacteria	KT	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,HTH_5,LMWPc
SRR21617310_k127_158019_7	1116232.AHBF01000116_gene4473	2.731e-08	64.0	COG2311@1|root,COG2311@2|Bacteria,2GQ7S@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR21617310_k127_158019_4	1206732.BAGD01000070_gene2721	8.356e-37	145.0	COG2311@1|root,COG2311@2|Bacteria,2GQ7S@201174|Actinobacteria,4FZGA@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR21617310_k127_158019_6	1120950.KB892739_gene3894	8.787e-14	81.0	COG2311@1|root,COG2311@2|Bacteria,2GQ7S@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR21617310_k127_158019_10	262316.MAP_4219	0.0008836	48.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR21617310_k127_158019_9	1123023.JIAI01000006_gene75	5.113e-07	57.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4EAJU@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_158019_0	1394178.AWOO02000031_gene4791	8.578e-277	867.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4EFWP@85012|Streptosporangiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_158019_1	1123023.JIAI01000006_gene75	6.981e-139	453.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4EAJU@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_158019_5	1123023.JIAI01000006_gene76	1.221e-27	112.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E9NR@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1582042_9	1136417.AZWE01000028_gene2563	8.81e-09	60.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DDQM@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_1582042_10	469371.Tbis_0587	3.131e-08	63.0	COG1008@1|root,COG1008@2|Bacteria,2GR9E@201174|Actinobacteria,4E6TJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR21617310_k127_1582042_5	1123023.JIAI01000002_gene5476	4.566e-75	262.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_1582042_4	1120949.KB903294_gene3739	3.701e-76	275.0	COG4585@1|root,COG4585@2|Bacteria,2I312@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PAS_4
SRR21617310_k127_1582042_8	1150864.MILUP08_41848	1.034e-51	187.0	COG1846@1|root,COG1846@2|Bacteria,2GMV1@201174|Actinobacteria,4DEG2@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_1582042_0	1179773.BN6_30480	2.962e-242	760.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4DYSV@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_1582042_2	345341.KUTG_02737	2.346e-199	643.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4DZMQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	1.2.1.18,1.2.1.27,2.6.1.19	ko:K00140,ko:K00823	ko00250,ko00280,ko00410,ko00562,ko00640,ko00650,ko01100,ko01120,ko01200,map00250,map00280,map00410,map00562,map00640,map00650,map01100,map01120,map01200	M00013,M00027	R00705,R00706,R00908,R00922,R00935,R01648	RC00004,RC00006,RC00062,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR21617310_k127_1582042_6	1449976.KALB_6474	4.847e-66	231.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4E4NM@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_1582042_1	351607.Acel_1287	9.036e-227	719.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4ERWH@85013|Frankiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR21617310_k127_1582042_3	263358.VAB18032_23365	9.33e-127	433.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR21617310_k127_1582042_7	1449346.JQMO01000003_gene3398	1.096e-54	195.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,2M22K@2063|Kitasatospora	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR21617310_k127_1601528_5	479434.Sthe_0004	6.221e-127	413.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi,27XTW@189775|Thermomicrobia	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1601528_25	1122609.AUGT01000033_gene590	6.447e-24	105.0	2B2IY@1|root,31V42@2|Bacteria,2GUYA@201174|Actinobacteria,4DS4M@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1601528_15	383372.Rcas_2639	3.199e-64	242.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
SRR21617310_k127_1601528_7	1123023.JIAI01000002_gene5912	1.618e-108	359.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4E2YP@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR21617310_k127_1601528_0	1894.JOER01000054_gene6003	8.006e-313	988.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1601528_11	1500301.JQMF01000038_gene5908	2.359e-78	271.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,4BM3M@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR21617310_k127_1601528_4	1500301.JQMF01000038_gene5909	1.317e-128	446.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,4B9HU@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	MA20_29500	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR21617310_k127_1601528_22	335543.Sfum_2141	1.031e-38	157.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1601528_10	1231391.AMZF01000020_gene2008	2.1e-87	303.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_1601528_2	97096.XP_007790920.1	2.404e-179	580.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR21617310_k127_1601528_24	1123319.AUBE01000036_gene2418	7.655e-26	110.0	2FBCB@1|root,343I6@2|Bacteria,2IM2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1601528_12	525909.Afer_0762	1.125e-77	268.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR21617310_k127_1601528_14	1120950.KB892708_gene4507	1.676e-64	233.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DUVR@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR21617310_k127_1601528_6	471852.Tcur_3151	1.947e-124	412.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4EFYK@85012|Streptosporangiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lprQ	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	YkuD
SRR21617310_k127_1601528_16	1869.MB27_12165	3.843e-63	221.0	COG4894@1|root,COG4894@2|Bacteria,2GKWI@201174|Actinobacteria,4DDQF@85008|Micromonosporales	201174|Actinobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
SRR21617310_k127_1601528_26	298654.FraEuI1c_6785	2.083e-10	71.0	2E388@1|root,32Y7X@2|Bacteria,2GQYZ@201174|Actinobacteria,4ETH9@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1601528_9	710111.FraQA3DRAFT_3880	2.446e-94	327.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.191,5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180,ko:K06969	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2,S4
SRR21617310_k127_1601528_13	469371.Tbis_1962	3.694e-66	237.0	COG1503@1|root,COG1503@2|Bacteria,2IFQH@201174|Actinobacteria,4E2MK@85010|Pseudonocardiales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1601528_21	251229.Chro_4563	2.271e-45	184.0	COG0642@1|root,COG3920@1|root,COG2205@2|Bacteria,COG3920@2|Bacteria,1GJ5I@1117|Cyanobacteria,3VMSA@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2
SRR21617310_k127_1601528_17	443255.SCLAV_3210	1.119e-53	210.0	COG2197@1|root,COG2208@1|root,COG2197@2|Bacteria,COG2208@2|Bacteria,2GNAF@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
SRR21617310_k127_1601528_1	1128421.JAGA01000003_gene3683	3.288e-222	706.0	COG5297@1|root,COG5297@2|Bacteria,2NQDB@2323|unclassified Bacteria	2|Bacteria	G	CBD_II	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_10,CBM_2,Glyco_hydro_6,PKD
SRR21617310_k127_1601528_8	287986.DV20_36540	3.548e-99	339.0	COG1387@1|root,COG1387@2|Bacteria,2HYSU@201174|Actinobacteria,4EBF6@85010|Pseudonocardiales	201174|Actinobacteria	E	histidinol phosphate phosphatase HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR21617310_k127_1601528_20	1120960.ATXG01000019_gene3404	2.011e-45	184.0	COG0667@1|root,COG0667@2|Bacteria,2ID5A@201174|Actinobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_1601528_23	1356854.N007_06280	2.222e-27	112.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27A9T@186823|Alicyclobacillaceae	91061|Bacilli	K	Cold-shock protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR21617310_k127_1601528_3	1123023.JIAI01000001_gene6153	1.326e-164	527.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_1601528_19	526226.Gbro_0449	2.886e-49	183.0	COG0454@1|root,COG0456@2|Bacteria,2HXQB@201174|Actinobacteria,4GGM9@85026|Gordoniaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR21617310_k127_1601528_18	1120950.KB892752_gene6189	1.031e-51	191.0	COG3576@1|root,COG3576@2|Bacteria,2I3PF@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1601528_27	350058.Mvan_2085	3.929e-08	59.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,235BF@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1603174_0	1206101.AZXC01000012_gene1175	2.996e-240	747.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR21617310_k127_1603174_2	35754.JNYJ01000043_gene4511	4.539e-97	336.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4DAVA@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR21617310_k127_1603174_1	266117.Rxyl_2413	1.17e-103	350.0	COG3387@1|root,COG3387@2|Bacteria,2ICV9@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1605618_10	309801.trd_A0246	1.202e-23	102.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Auxin_BP,Cupin_2
SRR21617310_k127_1605618_6	44060.JODL01000044_gene4017	4.445e-37	153.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR21617310_k127_1605618_3	55952.BU52_03630	8.263e-107	351.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR21617310_k127_1605618_0	1313172.YM304_31890	2.799e-268	846.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CMX3@84992|Acidimicrobiia	84992|Acidimicrobiia	P	E1-E2 ATPase	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K12956	-	-	R00086	RC00002	ko00000,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR21617310_k127_1605618_12	1120948.KB903229_gene4950	6.554e-17	82.0	COG2608@1|root,COG2608@2|Bacteria,2GXF6@201174|Actinobacteria,4EDAJ@85010|Pseudonocardiales	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR21617310_k127_1605618_9	1414719.CBYN010000047_gene764	2.578e-27	115.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,22NV0@1653|Corynebacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR21617310_k127_1605618_1	1120950.KB892757_gene6609	2.412e-206	659.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DU7F@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1605618_4	1121946.AUAX01000015_gene5945	4.55e-57	205.0	COG3795@1|root,COG3795@2|Bacteria,2IIV2@201174|Actinobacteria,4DFEQ@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_1605618_8	66429.JOFL01000002_gene4049	5.196e-29	124.0	COG3247@1|root,COG3247@2|Bacteria,2II04@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1605618_7	1120936.KB907209_gene1408	2.673e-31	131.0	2AD1W@1|root,312Q2@2|Bacteria,2GNNN@201174|Actinobacteria,4EP59@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1605618_11	240015.ACP_0158	1.307e-20	101.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR21617310_k127_1605618_2	1122138.AQUZ01000065_gene4288	1.473e-137	465.0	COG4451@1|root,COG4451@2|Bacteria,2I5D7@201174|Actinobacteria	201174|Actinobacteria	C	ribulose bisphosphate carboxylase, small	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
SRR21617310_k127_1605618_5	1122138.AQUZ01000019_gene8121	1.469e-51	207.0	COG4974@1|root,COG4974@2|Bacteria,2I9XB@201174|Actinobacteria,4DWHS@85009|Propionibacteriales	201174|Actinobacteria	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_1605618_13	1245475.ANAE01000146_gene2129	4.28e-05	51.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR21617310_k127_160994_3	543632.JOJL01000114_gene1399	1.166e-25	113.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_160994_4	543632.JOJL01000114_gene1399	2.269e-20	95.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_160994_2	1229780.BN381_460004	4.282e-59	209.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_160994_5	1240349.ANGC01000040_gene4381	2.548e-17	91.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4FUH7@85025|Nocardiaceae	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_160994_1	345341.KUTG_02457	8.317e-105	356.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,2ICCW@201174|Actinobacteria	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR21617310_k127_160994_0	1382306.JNIM01000001_gene2137	3.975e-142	458.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_161175_0	543632.JOJL01000097_gene5165	5.134e-114	383.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_161175_2	1229780.BN381_400049	1.564e-82	289.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_161175_1	110319.CF8_1675	2.768e-102	347.0	COG4974@1|root,COG4974@2|Bacteria,2IGA2@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_161175_3	749927.AMED_1065	1.203e-29	123.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4EAVH@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
SRR21617310_k127_1613339_7	479433.Caci_6164	2.365e-26	117.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_1613339_1	1211814.CAPG01000022_gene820	1.067e-164	544.0	COG3291@1|root,COG3291@2|Bacteria,1VT8V@1239|Firmicutes,4HTMV@91061|Bacilli,1ZMNY@1386|Bacillus	91061|Bacilli	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1613339_3	485913.Krac_4785	7.282e-84	288.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1613339_0	350058.Mvan_3810	0.0	1328.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,232MQ@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR21617310_k127_1613339_4	379066.GAU_3677	4.108e-71	246.0	COG4832@1|root,COG4832@2|Bacteria	2|Bacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR21617310_k127_1613339_2	471852.Tcur_0287	9.781e-110	362.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4EFKV@85012|Streptosporangiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_1613339_6	1120950.KB892740_gene2570	5.112e-40	156.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria,4DSFH@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_1613339_5	1157640.AQWO01000003_gene5758	1.637e-42	160.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_1615909_21	1121946.AUAX01000016_gene4621	2.177e-05	48.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_1615909_13	1120949.KB903312_gene606	5.708e-16	81.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_1615909_12	525909.Afer_0828	1.787e-16	87.0	COG0392@1|root,COG0392@2|Bacteria,2HG5A@201174|Actinobacteria,4CN1V@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR21617310_k127_1615909_20	106370.Francci3_2615	7.103e-06	54.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1615909_15	1123023.JIAI01000028_gene4487	7.547e-14	81.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E035@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1615909_14	106370.Francci3_2615	3.419e-14	74.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1615909_10	106370.Francci3_2615	4.866e-19	91.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1615909_0	1089551.KE386572_gene909	2.107e-135	445.0	COG1404@1|root,COG1404@2|Bacteria,1PG3I@1224|Proteobacteria,2V8W1@28211|Alphaproteobacteria,4BSXU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR21617310_k127_1615909_1	994479.GL877878_gene1167	3.398e-123	397.0	COG0582@1|root,COG0582@2|Bacteria,2GNX4@201174|Actinobacteria	201174|Actinobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1615909_22	1343740.M271_39725	0.0003365	45.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
SRR21617310_k127_1615909_6	1123024.AUII01000045_gene572	4.471e-52	195.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,GNAT_acetyltran
SRR21617310_k127_1615909_9	1397528.Q671_10275	6.64e-22	101.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SYA9@1236|Gammaproteobacteria,1XKG8@135619|Oceanospirillales	135619|Oceanospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR21617310_k127_1615909_16	1429046.RR21198_1702	6.925e-12	66.0	COG2021@1|root,COG3832@1|root,COG2021@2|Bacteria,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria,4G0YQ@85025|Nocardiaceae	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR21617310_k127_1615909_8	1448389.BAVQ01000002_gene2863	2.123e-29	121.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR21617310_k127_1615909_4	1386089.N865_00325	3.177e-57	209.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,GerE
SRR21617310_k127_1615909_17	1151119.KB895489_gene507	2.138e-11	69.0	2A6ZD@1|root,30VUF@2|Bacteria,2HA63@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1615909_5	1240349.ANGC01000006_gene1475	7.84e-55	205.0	COG3832@1|root,COG3832@2|Bacteria,2IBWM@201174|Actinobacteria,4G90C@85025|Nocardiaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1615909_7	1283283.ATXA01000005_gene2146	5.262e-39	161.0	COG1846@1|root,COG1846@2|Bacteria,2IQQ8@201174|Actinobacteria	201174|Actinobacteria	K	marr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
SRR21617310_k127_1615909_3	1380370.JIBA01000018_gene463	2.219e-76	271.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR21617310_k127_1615909_2	926550.CLDAP_33840	1.07e-107	360.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR21617310_k127_1615909_11	405948.SACE_4917	4.18e-17	85.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_1619677_3	1463825.JNXC01000024_gene5042	1.098e-40	154.0	COG3631@1|root,COG3631@2|Bacteria,2IQSN@201174|Actinobacteria,4E6KQ@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_1619677_4	309801.trd_0540	1.254e-35	143.0	COG0819@1|root,COG0819@2|Bacteria	2|Bacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
SRR21617310_k127_1619677_5	55952.BU52_05095	1.762e-20	106.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1619677_1	1123322.KB904677_gene3122	1.31e-84	297.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_1619677_2	1121946.AUAX01000019_gene7767	7.293e-63	231.0	2E4NZ@1|root,31V53@2|Bacteria,2HWJD@201174|Actinobacteria,4DJ2M@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2781)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2781
SRR21617310_k127_1619677_0	543632.JOJL01000052_gene6498	4.119e-87	306.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4DDU6@85008|Micromonosporales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR21617310_k127_1619677_6	1078020.KEK_15148	5.044e-09	58.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,237IR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR21617310_k127_162424_7	266117.Rxyl_0113	6.261e-71	255.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CSQX@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_162424_1	981369.JQMJ01000004_gene942	4.429e-299	938.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,2NHW8@228398|Streptacidiphilus	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_162424_10	644966.Tmar_1491	6.261e-68	237.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,3WDUM@538999|Clostridiales incertae sedis	186801|Clostridia	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_162424_19	1382356.JQMP01000004_gene232	4.621e-32	128.0	COG1975@1|root,COG1975@2|Bacteria,2G6Z8@200795|Chloroflexi,27YDJ@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
SRR21617310_k127_162424_15	266117.Rxyl_0117	1.2e-63	228.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CQ5H@84995|Rubrobacteria	84995|Rubrobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR21617310_k127_162424_24	479434.Sthe_1405	2.012e-23	115.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi,27YGF@189775|Thermomicrobia	189775|Thermomicrobia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR21617310_k127_162424_18	351607.Acel_1636	2.922e-38	154.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR21617310_k127_162424_23	1511.CLOST_1816	1.765e-23	111.0	COG2154@1|root,COG2154@2|Bacteria,1VQGU@1239|Firmicutes	1239|Firmicutes	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR21617310_k127_162424_27	1122609.AUGT01000020_gene1065	1e-10	67.0	2F62M@1|root,33YKZ@2|Bacteria,2GX5M@201174|Actinobacteria,4DSQ2@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_162424_3	502025.Hoch_2002	9.409e-95	321.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_162424_8	502025.Hoch_2001	2.013e-70	249.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z3A1@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_162424_0	502025.Hoch_2000	0.0	1195.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR21617310_k127_162424_12	644966.Tmar_1488	1.034e-66	240.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	coxF	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR21617310_k127_162424_21	219305.MCAG_03962	6.572e-27	117.0	2F8ME@1|root,340ZZ@2|Bacteria,2IJJP@201174|Actinobacteria,4DDGU@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_162424_4	28444.JODQ01000006_gene599	5.661e-86	297.0	COG1131@1|root,COG1131@2|Bacteria,2IE14@201174|Actinobacteria	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR21617310_k127_162424_5	28444.JODQ01000006_gene598	1.354e-84	296.0	COG0842@1|root,COG0842@2|Bacteria,2I9MM@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR21617310_k127_162424_2	1476583.DEIPH_ctg032orf0104	9.867e-262	860.0	COG1112@1|root,COG1674@1|root,COG1112@2|Bacteria,COG1674@2|Bacteria,1WN0T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
SRR21617310_k127_162424_17	749414.SBI_00138	4.866e-48	182.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_162424_16	1380390.JIAT01000011_gene2864	1.395e-63	239.0	2A4ZY@1|root,30KGA@2|Bacteria,2HRSX@201174|Actinobacteria,4CTW6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_162424_26	1120972.AUMH01000004_gene1475	5.171e-18	89.0	COG5496@1|root,COG5496@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_162424_6	1380390.JIAT01000011_gene2864	8.834e-84	296.0	2A4ZY@1|root,30KGA@2|Bacteria,2HRSX@201174|Actinobacteria,4CTW6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_162424_9	1298880.AUEV01000011_gene2693	4.543e-70	242.0	COG1670@1|root,COG1670@2|Bacteria,2IS6V@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_162424_22	867903.ThesuDRAFT_00714	1.641e-25	111.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes	1239|Firmicutes	S	Ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR21617310_k127_162424_13	1120934.KB894419_gene2140	8.406e-65	236.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4DYVB@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	chcB	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR21617310_k127_162424_11	469371.Tbis_1612	2.409e-67	238.0	COG2030@1|root,COG2030@2|Bacteria,2GIXP@201174|Actinobacteria,4E334@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR21617310_k127_162424_20	478741.JAFS01000001_gene1316	6.562e-27	126.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
SRR21617310_k127_162424_28	224325.AF_0099	1.117e-07	63.0	COG2405@1|root,arCOG00719@2157|Archaea,2XXKY@28890|Euryarchaeota	28890|Euryarchaeota	V	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	-
SRR21617310_k127_162424_14	570268.ANBB01000035_gene2355	3.554e-64	229.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4EHYC@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR21617310_k127_162424_25	1120949.KB903356_gene8587	3.921e-20	101.0	2ARQJ@1|root,31H1M@2|Bacteria,2IG4U@201174|Actinobacteria,4DD1P@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1625361_3	479435.Kfla_5539	5.984e-131	443.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR21617310_k127_1625361_12	102125.Xen7305DRAFT_00051270	9.792e-43	164.0	COG3224@1|root,COG3224@2|Bacteria,1G6PK@1117|Cyanobacteria,3VNMT@52604|Pleurocapsales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
SRR21617310_k127_1625361_7	106370.Francci3_0168	8.598e-106	347.0	COG0702@1|root,COG0702@2|Bacteria,2I234@201174|Actinobacteria,4EWMA@85013|Frankiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR21617310_k127_1625361_9	1003195.SCAT_2641	1.081e-57	213.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria	201174|Actinobacteria	M	Glycine betaine	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR21617310_k127_1625361_6	1463920.JOGB01000031_gene6074	1.778e-106	350.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1625361_0	1463881.KL591018_gene271	1.16e-311	982.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR21617310_k127_1625361_10	710421.Mycch_2074	1.342e-52	194.0	arCOG11509@1|root,31KIR@2|Bacteria,2IGM0@201174|Actinobacteria,23A9A@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1625361_8	1394178.AWOO02000059_gene591	1.451e-75	266.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,4EFMN@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRR21617310_k127_1625361_13	1048339.KB913029_gene1432	2.082e-23	100.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4ETDG@85013|Frankiales	201174|Actinobacteria	L	TIGRFAM DNA binding domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_1625361_11	68570.DC74_4007	9.929e-52	197.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1625361_4	1120973.AQXL01000131_gene2039	2.821e-126	414.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR21617310_k127_1625361_5	1380393.JHVP01000010_gene2916	1.632e-116	386.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4ERKV@85013|Frankiales	201174|Actinobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR21617310_k127_1625361_1	356851.JOAN01000026_gene1884	6.22e-184	599.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DB2D@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR21617310_k127_1625361_2	106370.Francci3_2860	7.806e-148	497.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_1625482_8	316274.Haur_3896	2.146e-12	70.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR21617310_k127_1625482_2	1283299.AUKG01000004_gene932	6.423e-99	330.0	COG0672@1|root,COG2822@1|root,COG0672@2|Bacteria,COG2822@2|Bacteria,2GJ22@201174|Actinobacteria,4CPU7@84995|Rubrobacteria	84995|Rubrobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR21617310_k127_1625482_7	1283299.AUKG01000004_gene932	2.374e-23	104.0	COG0672@1|root,COG2822@1|root,COG0672@2|Bacteria,COG2822@2|Bacteria,2GJ22@201174|Actinobacteria,4CPU7@84995|Rubrobacteria	84995|Rubrobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR21617310_k127_1625482_5	675635.Psed_0893	2.184e-66	234.0	COG2822@1|root,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria,4DYDF@85010|Pseudonocardiales	201174|Actinobacteria	P	Imelysin	efeO	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR21617310_k127_1625482_1	929712.KI912613_gene3374	1.679e-147	481.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR21617310_k127_1625482_6	67315.JOBD01000002_gene2906	9.54e-52	191.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR21617310_k127_1625482_4	909613.UO65_0811	2.644e-89	308.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DZTC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR21617310_k127_1625482_0	123214.PERMA_0609	3.004e-166	554.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G425@200783|Aquificae	200783|Aquificae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR21617310_k127_1625482_3	1968.JOEV01000017_gene3696	7.427e-98	353.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR21617310_k127_1626567_0	383372.Rcas_2990	1.848e-225	718.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,374S7@32061|Chloroflexia	32061|Chloroflexia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR21617310_k127_1626567_2	570268.ANBB01000027_gene582	2.614e-83	285.0	COG0783@1|root,COG0783@2|Bacteria,2HTPH@201174|Actinobacteria,4EIND@85012|Streptosporangiales	201174|Actinobacteria	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR21617310_k127_1626567_6	1089544.KB912942_gene1795	1.334e-17	87.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXU1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_1626567_5	1121430.JMLG01000017_gene291	5.462e-19	92.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,262GA@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Sporulation protein YteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR21617310_k127_1626567_7	1211815.CBYP010000073_gene3623	0.0001043	53.0	2BYAG@1|root,2ZC13@2|Bacteria,2IGUZ@201174|Actinobacteria,4EW5H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1626567_4	1380390.JIAT01000013_gene123	7.283e-37	143.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR21617310_k127_1626567_3	35754.JNYJ01000020_gene291	1.542e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria,4DD7T@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1626567_1	1108045.GORHZ_247_00370	2.208e-173	547.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM selenium-binding protein	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR21617310_k127_1627636_0	929712.KI912613_gene1492	1.666e-235	764.0	COG1061@1|root,COG1061@2|Bacteria,2GNGE@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR21617310_k127_1627636_4	345341.KUTG_07350	3.227e-34	142.0	2B36U@1|root,31VUU@2|Bacteria,2GW94@201174|Actinobacteria,4E6YV@85010|Pseudonocardiales	201174|Actinobacteria	S	ClpX C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-C4_ClpX
SRR21617310_k127_1627636_3	35754.JNYJ01000001_gene7449	2.763e-48	183.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	ant1	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
SRR21617310_k127_1627636_6	1297742.A176_01335	9.455e-16	85.0	COG0863@1|root,COG0863@2|Bacteria,1P97D@1224|Proteobacteria,42S8M@68525|delta/epsilon subdivisions,2X85U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_1627636_7	1297742.A176_01335	5.273e-11	71.0	COG0863@1|root,COG0863@2|Bacteria,1P97D@1224|Proteobacteria,42S8M@68525|delta/epsilon subdivisions,2X85U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_1627636_2	405948.SACE_3223	3.808e-96	321.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria,4E138@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR21617310_k127_1627636_1	479432.Sros_4136	6.595e-127	427.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4EHNW@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1627636_5	2002.JOEQ01000005_gene3432	9.533e-21	97.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4EICV@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_1627636_8	33876.JNXY01000039_gene6685	5.415e-10	61.0	2DMB2@1|root,32UGJ@2|Bacteria,2I1VY@201174|Actinobacteria,4DKEK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1643769_0	1120950.KB892787_gene159	1.015e-85	291.0	COG0330@1|root,COG0330@2|Bacteria,2IGTF@201174|Actinobacteria,4DSBT@85009|Propionibacteriales	201174|Actinobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_1643769_3	593907.Celgi_2714	5.965e-09	65.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F2SB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_1643769_1	479431.Namu_2715	3.547e-37	156.0	COG2214@1|root,COG2214@2|Bacteria,2GQTA@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1643769_2	937777.Deipe_2050	2.952e-11	74.0	29WNC@1|root,33GS8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1655165_3	47763.JNZA01000002_gene3339	5.057e-33	139.0	2AWXU@1|root,31NVG@2|Bacteria,2INAP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1655165_0	469383.Cwoe_0855	2.53e-81	271.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4CQC4@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR21617310_k127_1655165_5	1206725.BAFU01000181_gene2262	7.363e-19	98.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_33
SRR21617310_k127_1655165_9	665577.JH993790_gene5690	6.414e-06	57.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR21617310_k127_1655165_2	67332.FM21_17290	2.311e-33	143.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_1655165_7	33876.JNXY01000037_gene7963	2.303e-13	75.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,2GIR9@201174|Actinobacteria	201174|Actinobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Helicase_C,Lsr2,ResIII
SRR21617310_k127_1655165_6	298655.KI912266_gene1626	2.475e-17	83.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria	201174|Actinobacteria	L	Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR21617310_k127_1655165_4	268407.PWYN_19135	3.52e-20	98.0	29J5B@1|root,3062R@2|Bacteria,1TZ3D@1239|Firmicutes,4I8AB@91061|Bacilli,26ZE3@186822|Paenibacillaceae	268407.PWYN_19135|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1655165_8	479432.Sros_4421	3.932e-10	62.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4EMW1@85012|Streptosporangiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_1655165_1	68194.JNXR01000044_gene20	1.092e-39	151.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_1655302_0	66874.JOFS01000011_gene331	1.549e-142	471.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
SRR21617310_k127_1655302_1	570268.ANBB01000006_gene5431	9.485e-44	161.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4EFZA@85012|Streptosporangiales	201174|Actinobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_1671966_1	1380390.JIAT01000013_gene27	9.069e-93	321.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4CR3I@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_1671966_9	1122933.JNIY01000003_gene956	2.343e-25	117.0	COG3917@1|root,COG3917@2|Bacteria,2I2EX@201174|Actinobacteria,4F0YC@85016|Cellulomonadaceae	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR21617310_k127_1671966_10	1449355.JQNR01000005_gene3450	4.964e-25	113.0	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1671966_7	479434.Sthe_1268	1.957e-34	145.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1671966_0	1185876.BN8_01574	6.761e-113	376.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	2|Bacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR21617310_k127_1671966_11	684949.ATTJ01000002_gene246	1.546e-22	111.0	2DDJY@1|root,32U1P@2|Bacteria,1WKT2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR21617310_k127_1671966_3	1123322.KB904680_gene3260	7.128e-58	213.0	COG1443@1|root,COG1443@2|Bacteria,2GM26@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR21617310_k127_1671966_2	345341.KUTG_05227	1.348e-66	250.0	2B0YS@1|root,31TBU@2|Bacteria,2GPJZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR21617310_k127_1671966_4	929712.KI912613_gene831	1.689e-48	182.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria,4CQPT@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
SRR21617310_k127_1671966_5	211114.JOEF01000001_gene7187	3.027e-43	167.0	COG5553@1|root,COG5553@2|Bacteria,2I8K9@201174|Actinobacteria,4E62Z@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
SRR21617310_k127_1671966_8	326424.FRAAL2242	1.958e-33	131.0	COG2261@1|root,COG2261@2|Bacteria,2IQGM@201174|Actinobacteria,4ETK1@85013|Frankiales	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR21617310_k127_1671966_6	471853.Bcav_0243	3.429e-43	167.0	2C30W@1|root,33T8Q@2|Bacteria,2H1UH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR21617310_k127_1673634_0	1380370.JIBA01000003_gene2712	1.481e-88	319.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2GIRE@201174|Actinobacteria,4FGR4@85021|Intrasporangiaceae	201174|Actinobacteria	O	Subtilase family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR21617310_k127_1680495_6	32057.KB217478_gene6614	1.492e-41	155.0	COG2376@1|root,COG2376@2|Bacteria,1G0KN@1117|Cyanobacteria,1HK18@1161|Nostocales	1117|Cyanobacteria	G	Dihydroxyacetone kinase DhaK, subunit	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
SRR21617310_k127_1680495_4	653045.Strvi_3646	1.843e-100	340.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
SRR21617310_k127_1680495_5	1242864.D187_003377	5.932e-76	264.0	COG2267@1|root,COG2267@2|Bacteria,1R9DT@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1680495_7	649831.L083_6439	1.651e-38	147.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4DMMN@85008|Micromonosporales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR21617310_k127_1680495_1	1394178.AWOO02000016_gene6955	1.608e-143	472.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4EHJF@85012|Streptosporangiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR21617310_k127_1680495_2	644966.Tmar_1329	1.356e-142	467.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,25BU2@186801|Clostridia,3WDV5@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_1680495_3	351607.Acel_1371	9.741e-119	396.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4ESD3@85013|Frankiales	201174|Actinobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	lppS	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	YkuD
SRR21617310_k127_1680495_0	290397.Adeh_3892	7.903e-190	610.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YUEP@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR21617310_k127_1680736_0	861299.J421_2423	1.108e-225	726.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR21617310_k127_1680736_6	155515.JP36_02035	5.197e-36	145.0	COG1637@1|root,COG1637@2|Bacteria,1QHZA@1224|Proteobacteria,1TFRF@1236|Gammaproteobacteria,1Y9X7@135625|Pasteurellales	135625|Pasteurellales	L	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
SRR21617310_k127_1680736_1	103733.JNYO01000075_gene6400	1.049e-142	479.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,2ICNW@201174|Actinobacteria,4ED7Q@85010|Pseudonocardiales	201174|Actinobacteria	L	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
SRR21617310_k127_1680736_2	404589.Anae109_3002	2.501e-139	482.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR21617310_k127_1680736_5	512565.AMIS_1610	4.934e-48	182.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DINJ@85008|Micromonosporales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR21617310_k127_1680736_4	1194972.MVAC_01720	1.089e-51	196.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,235NM@1762|Mycobacteriaceae	201174|Actinobacteria	O	Peroxiredoxin	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR21617310_k127_1680736_3	1120950.KB892814_gene6933	6.365e-102	342.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR21617310_k127_1680736_7	1120934.KB894417_gene2328	3.168e-05	53.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4E44C@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR21617310_k127_1683462_1	316274.Haur_4702	2.349e-100	359.0	COG1396@1|root,COG2909@1|root,COG1396@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	msr0960	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
SRR21617310_k127_1683462_2	35754.JNYJ01000039_gene10005	1.066e-58	211.0	COG0563@1|root,COG0563@2|Bacteria,2IGX9@201174|Actinobacteria,4DM6N@85008|Micromonosporales	201174|Actinobacteria	F	Shikimate kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_33,SKI
SRR21617310_k127_1683462_0	1380393.JHVP01000005_gene3550	9.081e-181	575.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR21617310_k127_1691774_1	479433.Caci_1557	9.464e-63	220.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria	201174|Actinobacteria	C	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR21617310_k127_1691774_4	405948.SACE_3810	2.571e-29	130.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,4E1BB@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1691774_2	351607.Acel_0942	7.062e-59	226.0	COG1122@1|root,COG1122@2|Bacteria,2GMK1@201174|Actinobacteria	201174|Actinobacteria	P	ECF transporter, substrate-specific component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
SRR21617310_k127_1691774_0	1003195.SCAT_1422	1.375e-155	529.0	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR21617310_k127_1691774_3	1123322.KB904687_gene4994	3.142e-43	174.0	COG0619@1|root,COG0619@2|Bacteria,2GKHK@201174|Actinobacteria	201174|Actinobacteria	P	cobalt transport	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR21617310_k127_1691774_5	926550.CLDAP_33490	1.243e-10	70.0	COG1657@1|root,COG1657@2|Bacteria,2G7AD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1694976_5	134676.ACPL_3029	9.09e-08	54.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DC0B@85008|Micromonosporales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_1694976_0	1463881.KL591010_gene5152	1.98e-147	477.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR21617310_k127_1694976_3	1120950.KB892768_gene5315	6.125e-47	183.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria,4DVGZ@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR21617310_k127_1694976_1	1122611.KB903981_gene3435	1.774e-85	294.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4ENVP@85012|Streptosporangiales	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR21617310_k127_1694976_2	1229780.BN381_130292	7.859e-56	211.0	293RJ@1|root,2ZR76@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR21617310_k127_1694976_4	365528.KB891228_gene257	4.42e-43	168.0	COG0044@1|root,COG0044@2|Bacteria,2IAM1@201174|Actinobacteria,4ETRX@85013|Frankiales	201174|Actinobacteria	F	allantoinase	-	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR21617310_k127_1695896_1	31234.CRE13870	6.695e-05	54.0	COG0353@1|root,2R5W4@2759|Eukaryota,39H2B@33154|Opisthokonta,3CKWG@33208|Metazoa,3E2GZ@33213|Bilateria,40Q5V@6231|Nematoda,1M7PD@119089|Chromadorea,416B3@6236|Rhabditida	33208|Metazoa	L	RecR protein	-	-	-	-	-	-	-	-	-	-	-	-	RecR
SRR21617310_k127_1695896_0	1463920.JOGB01000057_gene6391	1.813e-115	411.0	COG3209@1|root,COG3209@2|Bacteria,2I35N@201174|Actinobacteria	201174|Actinobacteria	M	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_A2_3,RHS_repeat
SRR21617310_k127_1695896_2	929712.KI912613_gene4040	0.0001752	49.0	2ABYJ@1|root,311FZ@2|Bacteria,2GXNB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1697919_2	1380356.JNIK01000005_gene937	3.186e-05	46.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_1697919_1	479432.Sros_5190	1.561e-15	82.0	COG0406@1|root,COG0406@2|Bacteria,2GTM9@201174|Actinobacteria	201174|Actinobacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1697919_0	215803.DB30_0757	8.772e-20	103.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YWRH@29|Myxococcales	28221|Deltaproteobacteria	L	OB-fold nucleic acid binding domain	-	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR21617310_k127_1702661_8	1214242.B446_01455	6.359e-11	72.0	2ATXZ@1|root,31JHI@2|Bacteria,2GN21@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR21617310_k127_1702661_0	1380390.JIAT01000009_gene1363	1.287e-164	527.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4CU4I@84995|Rubrobacteria	84995|Rubrobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR21617310_k127_1702661_2	1123322.KB904634_gene2350	1.353e-61	216.0	COG3557@1|root,COG3557@2|Bacteria,2IFIQ@201174|Actinobacteria	201174|Actinobacteria	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
SRR21617310_k127_1702661_5	1463825.JNXC01000022_gene623	3.927e-44	169.0	COG2211@1|root,COG2211@2|Bacteria,2I3V7@201174|Actinobacteria,4E2C1@85010|Pseudonocardiales	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_1702661_4	35754.JNYJ01000020_gene259	9.868e-50	189.0	COG0477@1|root,COG2814@2|Bacteria,2IF5M@201174|Actinobacteria,4D8SR@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
SRR21617310_k127_1702661_3	208444.JNYY01000001_gene4994	1.054e-55	200.0	COG0640@1|root,COG0640@2|Bacteria,2IEHG@201174|Actinobacteria,4E40T@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_1702661_6	2074.JNYD01000005_gene3171	1.423e-32	131.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4E4U9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_1702661_1	35754.JNYJ01000016_gene9287	3.957e-98	331.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DF11@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1702661_7	1210045.ALNP01000001_gene3370	3.431e-16	79.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT
SRR21617310_k127_1702777_2	749414.SBI_03563	5.776e-44	167.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR21617310_k127_1702777_3	1299327.I546_5948	1.69e-39	149.0	28NDD@1|root,2ZBG6@2|Bacteria,2H1UZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1702777_0	926560.KE387023_gene2382	3.551e-126	414.0	COG0604@1|root,COG0604@2|Bacteria,1WM0U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR21617310_k127_1702777_4	1312959.KI914662_gene3877	4.47e-21	97.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1702777_1	1123024.AUII01000021_gene11	1.685e-123	400.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4E3S9@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR21617310_k127_1712843_6	391037.Sare_4989	2.563e-58	220.0	COG0642@1|root,COG2205@2|Bacteria,2I53J@201174|Actinobacteria,4DMQB@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1712843_5	1123023.JIAI01000001_gene6483	8.182e-63	225.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR21617310_k127_1712843_1	123214.PERMA_0647	6.395e-185	591.0	COG1350@1|root,COG1350@2|Bacteria,2G4P9@200783|Aquificae	200783|Aquificae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_1712843_2	1121468.AUBR01000014_gene2228	1.665e-150	489.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,42EWK@68295|Thermoanaerobacterales	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_1712843_4	1122622.ATWJ01000010_gene1386	3.572e-63	242.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4FEEI@85021|Intrasporangiaceae	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR21617310_k127_1712843_0	1394178.AWOO02000040_gene8600	6.812e-264	829.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4EG49@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR21617310_k127_1712843_3	105422.BBPM01000007_gene6455	2.951e-68	243.0	COG3780@1|root,COG3780@2|Bacteria,2HX4P@201174|Actinobacteria,2NJP2@228398|Streptacidiphilus	201174|Actinobacteria	L	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
SRR21617310_k127_1713499_2	1380390.JIAT01000011_gene2469	3.642e-72	252.0	COG1708@1|root,COG1895@1|root,COG1708@2|Bacteria,COG1895@2|Bacteria,2IQ25@201174|Actinobacteria,4CQYA@84995|Rubrobacteria	84995|Rubrobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,UPF0158
SRR21617310_k127_1713499_8	1123024.AUII01000002_gene849	9.015e-22	100.0	COG1895@1|root,COG1895@2|Bacteria	2|Bacteria	O	HEPN domain	-	-	-	ko:K09132	-	-	-	-	ko00000	-	-	-	HEPN
SRR21617310_k127_1713499_4	33876.JNXY01000039_gene6685	1.321e-40	157.0	2DMB2@1|root,32UGJ@2|Bacteria,2I1VY@201174|Actinobacteria,4DKEK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1713499_1	543632.JOJL01000030_gene3438	2.849e-75	257.0	28MFE@1|root,2ZASW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_1713499_6	483219.LILAB_10105	4.603e-33	132.0	28IV0@1|root,2Z8TM@2|Bacteria,1QK38@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1713499_7	483219.LILAB_10105	3.514e-32	135.0	28IV0@1|root,2Z8TM@2|Bacteria,1QK38@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1713499_0	502025.Hoch_1141	9.685e-98	332.0	28HTA@1|root,2Z806@2|Bacteria,1R7QM@1224|Proteobacteria,438M2@68525|delta/epsilon subdivisions,2X770@28221|Deltaproteobacteria,2YYUC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1713499_5	1133849.O3I_004225	2.289e-40	156.0	COG5573@1|root,COG5573@2|Bacteria,2GY55@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_1713499_3	543632.JOJL01000030_gene3438	4.151e-43	163.0	28MFE@1|root,2ZASW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_1714033_15	326427.Cagg_3053	1.069e-11	72.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi,375A7@32061|Chloroflexia	32061|Chloroflexia	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR21617310_k127_1714033_3	1122182.KB903814_gene3218	1.516e-140	462.0	COG0726@1|root,COG0726@2|Bacteria,2H2Y1@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_11	1120948.KB903243_gene2394	5.796e-60	228.0	2E29A@1|root,30QXH@2|Bacteria,2H74E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_10	324602.Caur_0890	2.181e-67	244.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
SRR21617310_k127_1714033_8	106370.Francci3_1562	2.11e-99	368.0	COG0438@1|root,COG0438@2|Bacteria,2GSQI@201174|Actinobacteria,4ES49@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR21617310_k127_1714033_6	1122182.KB903814_gene3223	1.026e-102	352.0	2BMB9@1|root,32FVB@2|Bacteria,2H352@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_7	1122138.AQUZ01000011_gene5013	8.327e-101	359.0	COG0728@1|root,COG0728@2|Bacteria,2II3T@201174|Actinobacteria	201174|Actinobacteria	S	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MVIN
SRR21617310_k127_1714033_18	1123023.JIAI01000002_gene4743	1.738e-07	64.0	2BPH7@1|root,32I9M@2|Bacteria,2H6SY@201174|Actinobacteria,4EBV4@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_12	994479.GL877878_gene3232	3.465e-55	201.0	COG2148@1|root,COG2148@2|Bacteria,2INBG@201174|Actinobacteria	201174|Actinobacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR21617310_k127_1714033_4	1122182.KB903814_gene3228	6.499e-124	406.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DCYX@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR21617310_k127_1714033_13	882083.SacmaDRAFT_5353	1.229e-43	169.0	COG1853@1|root,COG1853@2|Bacteria,2IJ0Q@201174|Actinobacteria,4E5F8@85010|Pseudonocardiales	201174|Actinobacteria	S	Flavin reductase like domain	actVB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0055114	-	ko:K14631	ko01057,ko01130,map01057,map01130	M00779	R05705	RC00126	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavin_Reduct
SRR21617310_k127_1714033_19	1463854.JOHT01000001_gene2836	4.235e-07	57.0	COG1012@1|root,COG1012@2|Bacteria,2GMFF@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR21617310_k127_1714033_2	1120948.KB903243_gene2390	2.502e-187	601.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria,4E14R@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K21780	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1714033_5	330214.NIDE2693	3.45e-122	406.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	MA20_09865	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR21617310_k127_1714033_20	525897.Dbac_0714	1.009e-05	58.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PKS@68525|delta/epsilon subdivisions,2WKCD@28221|Deltaproteobacteria,2M8VY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,SBP_bac_3,dCache_1
SRR21617310_k127_1714033_17	1123251.ATWM01000001_gene592	3.198e-10	72.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2HXHD@201174|Actinobacteria,4FGVZ@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR21617310_k127_1714033_0	1108045.GORHZ_073_00030	0.0	2285.0	COG0457@1|root,COG2885@1|root,COG2931@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,COG2931@2|Bacteria,2IBAR@201174|Actinobacteria	201174|Actinobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_9	365528.KB891223_gene1318	4.628e-87	311.0	COG1502@1|root,COG1502@2|Bacteria,2H9IE@201174|Actinobacteria	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR21617310_k127_1714033_1	1108045.GORHZ_073_00050	4.48e-231	766.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_21	1120949.KB903332_gene9335	0.0005362	51.0	2ASES@1|root,31HUI@2|Bacteria,2IH78@201174|Actinobacteria,4DCQ1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1714033_14	1283283.ATXA01000028_gene4049	1.602e-21	95.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR21617310_k127_1714033_16	405948.SACE_6168	6.121e-11	64.0	COG1309@1|root,COG1309@2|Bacteria,2IFKE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1716578_1	2055.JNXA01000005_gene534	2.529e-132	432.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4GF7K@85026|Gordoniaceae	201174|Actinobacteria	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1,Epimerase
SRR21617310_k127_1716578_0	1120949.KB903317_gene1732	2.05e-266	831.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	2|Bacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR21617310_k127_1716578_2	390989.JOEG01000006_gene818	1.479e-98	334.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4DAFF@85008|Micromonosporales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR21617310_k127_1716578_3	1449346.JQMO01000002_gene1977	3.967e-82	282.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,2M2HA@2063|Kitasatospora	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR21617310_k127_1716578_5	1079986.JH164851_gene1285	6.093e-06	48.0	COG0596@1|root,COG0596@2|Bacteria,2I4XA@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1716578_4	1380347.JNII01000006_gene1902	2.402e-46	170.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_1718565_6	105420.BBPO01000040_gene825	6.917e-76	282.0	COG1295@1|root,COG1295@2|Bacteria,2HMQ0@201174|Actinobacteria,2NGCJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR21617310_k127_1718565_1	448385.sce7660	8.982e-218	689.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YU3K@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR21617310_k127_1718565_10	1146883.BLASA_4090	1.371e-60	239.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4ESA1@85013|Frankiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR21617310_k127_1718565_3	479432.Sros_6208	2.668e-99	341.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4EHRB@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR21617310_k127_1718565_11	1206720.BAFQ01000269_gene5656	1.028e-41	168.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,4FYH9@85025|Nocardiaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR21617310_k127_1718565_0	1123322.KB904659_gene1029	0.0	1845.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria	201174|Actinobacteria	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
SRR21617310_k127_1718565_12	1429046.RR21198_4708	4.971e-35	138.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4G2TR@85025|Nocardiaceae	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_1718565_7	266117.Rxyl_1776	1.796e-73	254.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
SRR21617310_k127_1718565_5	287986.DV20_27720	9.365e-78	263.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4E3HT@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_3
SRR21617310_k127_1718565_2	405948.SACE_2200	3.505e-136	439.0	COG0596@1|root,COG0596@2|Bacteria,2GJCT@201174|Actinobacteria,4DZI3@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_1718565_9	298654.FraEuI1c_0358	2.505e-70	263.0	COG0715@1|root,COG0715@2|Bacteria,2HU25@201174|Actinobacteria,4EWJ0@85013|Frankiales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR21617310_k127_1718565_8	298654.FraEuI1c_0357	4.237e-72	263.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050,ko:K15599	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
SRR21617310_k127_1718565_4	298654.FraEuI1c_0356	2.495e-82	282.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EU1S@85013|Frankiales	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
SRR21617310_k127_1722056_4	105422.BBPM01000105_gene4292	2.714e-90	308.0	COG5322@1|root,COG5322@2|Bacteria,2IEVX@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Semialdhyde_dh,Shikimate_DH
SRR21617310_k127_1722056_5	717785.HYPMC_0139	1.711e-45	186.0	COG0531@1|root,COG0531@2|Bacteria,1MY59@1224|Proteobacteria,2TU3D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_1722056_7	1170562.Cal6303_0033	8.229e-12	68.0	COG2197@1|root,COG2197@2|Bacteria,1G33W@1117|Cyanobacteria,1HKMJ@1161|Nostocales	1117|Cyanobacteria	KT	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1722056_1	1242864.D187_003103	1.495e-150	503.0	COG2409@1|root,COG2409@2|Bacteria,1R9Z8@1224|Proteobacteria	1224|Proteobacteria	S	MMPL family	ydfJ	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_1722056_2	1123023.JIAI01000006_gene54	4.048e-147	478.0	COG1960@1|root,COG1960@2|Bacteria,2GZNN@201174|Actinobacteria,4DZP3@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_1722056_3	44060.JODL01000004_gene2529	3.64e-125	418.0	COG3221@1|root,COG3221@2|Bacteria,2GK9B@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
SRR21617310_k127_1722056_0	44060.JODL01000004_gene2530	3.195e-177	569.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1722056_6	562983.HMPREF0433_01420	3.966e-12	71.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3WEFK@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR21617310_k127_1723175_8	1469607.KK073767_gene216	3.143e-19	93.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HQD5@1161|Nostocales	1117|Cyanobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_1723175_6	446471.Xcel_1645	2.284e-43	162.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4F4BT@85017|Promicromonosporaceae	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR21617310_k127_1723175_4	2002.JOEQ01000015_gene5169	2.289e-55	218.0	2EGUB@1|root,33AKH@2|Bacteria,2I97J@201174|Actinobacteria,4EP8N@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1723175_3	1121926.AXWO01000008_gene2973	1.859e-69	250.0	COG3239@1|root,COG3239@2|Bacteria,2IFJ8@201174|Actinobacteria	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR21617310_k127_1723175_7	1380391.JIAS01000011_gene5219	4.075e-22	111.0	COG3382@1|root,COG3382@2|Bacteria	2|Bacteria	J	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
SRR21617310_k127_1723175_1	1380390.JIAT01000012_gene3007	7.87e-88	305.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4CPQ2@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_1723175_5	469371.Tbis_3508	5.11e-55	205.0	2F0JC@1|root,33TN2@2|Bacteria,2GPGJ@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_1723175_2	1123319.AUBE01000007_gene3772	1.045e-76	274.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR21617310_k127_1723175_0	103733.JNYO01000022_gene6958	1.235e-165	544.0	COG0318@1|root,COG0318@2|Bacteria,2I2RH@201174|Actinobacteria,4DYR0@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR21617310_k127_1726000_2	1122611.KB904008_gene5425	5.576e-24	102.0	COG3335@1|root,COG3335@2|Bacteria,2GV6N@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1726000_3	345341.KUTG_08618	1.7e-14	78.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_1726000_1	43759.JNWK01000001_gene5574	1.549e-25	117.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR21617310_k127_1736969_1	390989.JOEG01000025_gene33	1.148e-188	598.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DABQ@85008|Micromonosporales	201174|Actinobacteria	E	GMC oxidoreductase	choA	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR21617310_k127_1736969_0	337191.KTR9_2544	3.705e-195	638.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4GFZ2@85026|Gordoniaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	gabD2	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_1736969_5	391623.TERMP_00992	2.312e-19	100.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR21617310_k127_1736969_2	68223.JNZY01000070_gene5889	4.102e-96	337.0	COG1357@1|root,COG1357@2|Bacteria,2GJC1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide_3
SRR21617310_k127_1736969_3	1206733.BAGC01000111_gene6932	1.168e-37	150.0	COG1201@1|root,COG1201@2|Bacteria,2GK56@201174|Actinobacteria,4FY31@85025|Nocardiaceae	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR21617310_k127_1736969_6	994479.GL877879_gene5479	8.601e-19	92.0	COG1595@1|root,COG1595@2|Bacteria,2GUGU@201174|Actinobacteria,4E8EB@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1736969_4	219305.MCAG_03870	3.686e-33	145.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4DHSH@85008|Micromonosporales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_1748482_0	471857.Svir_31520	2.07e-140	456.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DYE8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR21617310_k127_1748482_7	1463903.JOIZ01000008_gene4412	1.697e-26	117.0	COG3255@1|root,COG3255@2|Bacteria,2GWVN@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR21617310_k127_1748482_4	512565.AMIS_41710	2.378e-39	156.0	COG3568@1|root,COG3568@2|Bacteria,2GP3V@201174|Actinobacteria,4DAXI@85008|Micromonosporales	201174|Actinobacteria	L	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR21617310_k127_1748482_10	863239.AFIZ01000007_gene91	6.226e-17	87.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria,22JRA@1653|Corynebacteriaceae	201174|Actinobacteria	FG	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR21617310_k127_1748482_5	1094715.CM001373_gene510	6.985e-35	142.0	COG0077@1|root,COG0077@2|Bacteria,1PK3E@1224|Proteobacteria,1RXS0@1236|Gammaproteobacteria,1JDA9@118969|Legionellales	118969|Legionellales	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
SRR21617310_k127_1748482_11	1123065.ATWL01000011_gene92	5.49e-09	62.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_1748482_9	1435356.Y013_01820	1.487e-17	91.0	2EF54@1|root,338Y8@2|Bacteria,2GSEE@201174|Actinobacteria,4G4NM@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1748482_6	47763.JNZA01000009_gene5473	6.93e-32	132.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR21617310_k127_1748482_2	479433.Caci_2820	1.854e-53	199.0	COG1437@1|root,COG1437@2|Bacteria,2IFDG@201174|Actinobacteria	201174|Actinobacteria	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
SRR21617310_k127_1748482_1	330084.JNYZ01000003_gene2272	9.174e-81	278.0	COG5606@1|root,COG5606@2|Bacteria,2I9ES@201174|Actinobacteria	201174|Actinobacteria	S	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1748482_8	1449350.OCH239_09140	2.499e-25	113.0	COG0789@1|root,COG0789@2|Bacteria,1QV2E@1224|Proteobacteria,2TW8U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SRR21617310_k127_1748482_12	136993.KB900626_gene3028	0.0001799	49.0	COG4634@1|root,COG4634@2|Bacteria,1N9QC@1224|Proteobacteria,2UISH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
SRR21617310_k127_1748482_3	390989.JOEG01000021_gene2652	5.369e-44	169.0	COG0664@1|root,COG0664@2|Bacteria,2I7B7@201174|Actinobacteria,4DAN8@85008|Micromonosporales	201174|Actinobacteria	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR21617310_k127_1748901_0	405948.SACE_2445	2.059e-117	397.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4E01Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR21617310_k127_1748901_1	42256.RradSPS_3021	1.933e-87	297.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,4CQSD@84995|Rubrobacteria	84995|Rubrobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR21617310_k127_1748901_3	1298863.AUEP01000022_gene1867	2.028e-15	87.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR21617310_k127_1748901_2	479432.Sros_7305	4.971e-25	105.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4EJZ6@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_1748901_4	1463881.KL591008_gene1889	6.792e-06	48.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_1751339_7	713586.KB900536_gene1119	4.611e-69	241.0	COG0500@1|root,COG0500@2|Bacteria,1QYGH@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_1751339_12	1123258.AQXZ01000013_gene1934	5.156e-31	129.0	2E4PM@1|root,32ZI9@2|Bacteria,2IMT3@201174|Actinobacteria,4G52Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1751339_0	477641.MODMU_2528	3.641e-195	623.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR21617310_k127_1751339_15	1380390.JIAT01000011_gene2469	2.389e-10	66.0	COG1708@1|root,COG1895@1|root,COG1708@2|Bacteria,COG1895@2|Bacteria,2IQ25@201174|Actinobacteria,4CQYA@84995|Rubrobacteria	84995|Rubrobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,UPF0158
SRR21617310_k127_1751339_4	1120949.KB903330_gene9147	1.508e-94	316.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D9QU@85008|Micromonosporales	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_1751339_5	1120949.KB903330_gene9148	1.174e-90	312.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DA7P@85008|Micromonosporales	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_1751339_3	1120949.KB903330_gene9149	1.613e-114	394.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria,4DJPW@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1751339_2	1120949.KB903330_gene9150	1.795e-127	414.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4DM3Q@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1751339_1	1120949.KB903330_gene9151	3.641e-156	502.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria,4DK6Z@85008|Micromonosporales	201174|Actinobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_1751339_6	1120949.KB903330_gene9152	2.791e-69	244.0	COG1802@1|root,COG1802@2|Bacteria,2H1S8@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_1751339_10	1123023.JIAI01000003_gene3071	9.981e-38	151.0	COG0702@1|root,COG0702@2|Bacteria,2HC75@201174|Actinobacteria,4E2JF@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR21617310_k127_1751339_13	2002.JOEQ01000016_gene7347	1.771e-14	86.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR21617310_k127_1751339_16	208439.AJAP_31555	3.245e-07	57.0	2EI1M@1|root,33BT3@2|Bacteria,2GXU9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1751339_8	996637.SGM_4882	1.174e-43	172.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,HTH_31,WD40
SRR21617310_k127_1751339_11	1463845.JOIG01000003_gene4897	2.257e-37	148.0	COG1487@1|root,COG1487@2|Bacteria,2ISD3@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_1751339_14	1463909.KL585973_gene87	4.961e-14	79.0	COG4118@1|root,COG4118@2|Bacteria,2GQXR@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR21617310_k127_1751339_9	543632.JOJL01000030_gene3438	2.681e-40	159.0	28MFE@1|root,2ZASW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_1752724_3	1460635.JCM19038_3982	7.452e-47	186.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR21617310_k127_1752724_2	1122138.AQUZ01000019_gene8187	2.65e-54	198.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR21617310_k127_1752724_4	285535.JOEY01000028_gene7308	1.378e-11	74.0	2EK1S@1|root,33DS8@2|Bacteria,2H41Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1752724_0	1157640.AQWO01000005_gene2020	2.58e-116	382.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_1752724_1	1032480.MLP_33130	3.542e-74	252.0	COG4430@1|root,COG4430@2|Bacteria,2IQK3@201174|Actinobacteria	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR21617310_k127_1771186_16	1150469.RSPPHO_03261	1.693e-35	135.0	2DP8N@1|root,3311E@2|Bacteria,1NC4X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1771186_29	1122925.KB895390_gene1482	0.0008302	46.0	29KS2@1|root,307PG@2|Bacteria,1U1ZU@1239|Firmicutes,4IBGM@91061|Bacilli,2748K@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1771186_20	35754.JNYJ01000011_gene609	1.248e-26	126.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4D9EM@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR21617310_k127_1771186_7	68260.JOAY01000057_gene5333	1.121e-83	297.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_1771186_9	760568.Desku_1708	4.208e-75	271.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR21617310_k127_1771186_23	266940.Krad_3151	9.543e-17	85.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR21617310_k127_1771186_15	1306174.JODP01000002_gene6052	2.809e-48	193.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR21617310_k127_1771186_6	1463909.KL585972_gene3593	2.702e-86	293.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR21617310_k127_1771186_24	58344.JOEL01000006_gene4807	1.742e-15	80.0	COG3255@1|root,COG3255@2|Bacteria,2IM6I@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR21617310_k127_1771186_30	1218173.BALCAV_0211965	0.0009356	49.0	COG3937@1|root,COG3937@2|Bacteria,1VF6E@1239|Firmicutes,4HPBK@91061|Bacilli,1ZIWR@1386|Bacillus	91061|Bacilli	S	ATP synthase, subunit b	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR21617310_k127_1771186_8	1123024.AUII01000041_gene1746	7.015e-80	275.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4DY8F@85010|Pseudonocardiales	201174|Actinobacteria	J	TIGRFAM hemolysin TlyA family protein	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR21617310_k127_1771186_11	103733.JNYO01000003_gene8362	3.439e-55	214.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4DYJH@85010|Pseudonocardiales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR21617310_k127_1771186_1	1907.SGLAU_07860	3.332e-148	488.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR21617310_k127_1771186_4	471852.Tcur_2172	4.351e-125	433.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4EHB1@85012|Streptosporangiales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR21617310_k127_1771186_22	405948.SACE_5246	3.019e-22	108.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4DZE1@85010|Pseudonocardiales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR21617310_k127_1771186_12	429009.Adeg_1389	1.301e-50	196.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,25E7R@186801|Clostridia,42FZK@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_1771186_17	1123320.KB889701_gene9162	1.469e-34	144.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1771186_0	1382304.JNIL01000001_gene2317	5.145e-224	713.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,277XG@186823|Alicyclobacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR21617310_k127_1771186_19	479434.Sthe_1370	1.417e-29	129.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi,27YF6@189775|Thermomicrobia	189775|Thermomicrobia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR21617310_k127_1771186_2	219305.MCAG_04961	2.224e-146	473.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DA3S@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR21617310_k127_1771186_5	1120958.AULD01000008_gene700	5.952e-90	308.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FMIB@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_1771186_25	1043205.AFYF01000017_gene1036	8.75e-12	76.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FGBX@85021|Intrasporangiaceae	201174|Actinobacteria	T	DNA-binding protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR21617310_k127_1771186_3	1121430.JMLG01000003_gene532	1.677e-133	437.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR21617310_k127_1771186_27	67373.JOBF01000015_gene5186	1.558e-06	58.0	COG0500@1|root,COG2226@2|Bacteria,2II6W@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_1771186_10	1068978.AMETH_3456	4.085e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,2IMF7@201174|Actinobacteria,4E68E@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1771186_18	298654.FraEuI1c_4243	1.508e-32	132.0	COG3631@1|root,COG3631@2|Bacteria,2II8D@201174|Actinobacteria	201174|Actinobacteria	S	COG3631 Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_1771186_28	1463821.JOGR01000002_gene464	8.661e-05	49.0	COG1742@1|root,COG1742@2|Bacteria,2IKM8@201174|Actinobacteria,4EYNX@85014|Glycomycetales	201174|Actinobacteria	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR21617310_k127_1771186_13	1896.JOAU01000002_gene3920	4.292e-50	190.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR21617310_k127_1771186_21	479432.Sros_0713	2.427e-25	110.0	2DPGP@1|root,331ZU@2|Bacteria,2GR4I@201174|Actinobacteria,4EKHE@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1771186_14	351607.Acel_1240	4.759e-49	178.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR21617310_k127_1774719_0	1894.JOER01000046_gene4605	2.031e-252	791.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
SRR21617310_k127_1774719_4	298655.KI912266_gene1594	1.576e-32	141.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4ERQ9@85013|Frankiales	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1774719_2	525368.HMPREF0591_4429	6.096e-91	312.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,239QV@1762|Mycobacteriaceae	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1774719_3	350058.Mvan_1114	7.883e-40	152.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,236NP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1774719_9	1229780.BN381_600015	2.5e-15	83.0	28UAI@1|root,2ZGG0@2|Bacteria,2GTER@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1774719_5	1265502.KB905972_gene1348	6.686e-24	103.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,4AASI@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
SRR21617310_k127_1774719_8	1463887.KL589965_gene6164	1.261e-15	79.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
SRR21617310_k127_1774719_7	1463909.KL585953_gene5647	1.477e-20	99.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR21617310_k127_1774719_10	1123023.JIAI01000010_gene8545	8.426e-10	60.0	COG0242@1|root,COG0242@2|Bacteria,2GJT4@201174|Actinobacteria,4DZPG@85010|Pseudonocardiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
SRR21617310_k127_1774719_1	1079986.JH164837_gene5596	9.984e-97	322.0	COG0500@1|root,COG2226@2|Bacteria,2IAGR@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_1779633_5	1267534.KB906755_gene4395	1.95e-132	435.0	COG1004@1|root,COG1004@2|Bacteria,3Y3GR@57723|Acidobacteria,2JHU0@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR21617310_k127_1779633_2	526227.Mesil_2749	7.365e-190	619.0	COG0451@1|root,COG1372@1|root,COG0451@2|Bacteria,COG1372@2|Bacteria,1WJB0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_1779633_9	58123.JOFJ01000002_gene2600	3.765e-70	248.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria,4EGP9@85012|Streptosporangiales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
SRR21617310_k127_1779633_14	134676.ACPL_868	6.736e-31	136.0	2DHRC@1|root,32U9K@2|Bacteria,2II2K@201174|Actinobacteria,4DM9E@85008|Micromonosporales	201174|Actinobacteria	S	Family of unknown function (DUF5319)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5319
SRR21617310_k127_1779633_3	1121877.JQKF01000009_gene498	3.487e-188	594.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR21617310_k127_1779633_1	1121877.JQKF01000009_gene497	2.121e-201	647.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CMTF@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR21617310_k127_1779633_13	1382356.JQMP01000001_gene992	5.837e-32	142.0	COG1881@1|root,COG1881@2|Bacteria,2G6ZP@200795|Chloroflexi,27Z5Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR21617310_k127_1779633_8	358823.DF19_15510	1.426e-83	300.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR21617310_k127_1779633_4	196162.Noca_4177	3.018e-147	473.0	COG1063@1|root,COG1063@2|Bacteria,2GKFG@201174|Actinobacteria,4DTHT@85009|Propionibacteriales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
SRR21617310_k127_1779633_15	263358.VAB18032_03995	1.642e-18	98.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4D97R@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_1779633_17	43759.JNWK01000079_gene3941	5.367e-08	63.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_1779633_6	479432.Sros_1321	3.663e-102	341.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EHSQ@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1779633_10	443144.GM21_3060	1.671e-66	245.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR21617310_k127_1779633_11	345341.KUTG_01275	3.796e-44	162.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR21617310_k127_1779633_12	1120950.KB892754_gene6001	5.663e-39	153.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4DS2R@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_1779633_7	1121877.JQKF01000003_gene1489	2.501e-100	337.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CMZ4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_1779633_0	1229780.BN381_130048	8.229e-241	767.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,3UWC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR21617310_k127_1779633_18	446470.Snas_5726	8.529e-05	48.0	COG0640@1|root,COG0640@2|Bacteria,2GPH2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,MarR_2
SRR21617310_k127_1787834_1	1121946.AUAX01000006_gene3347	1.103e-257	809.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4DAYP@85008|Micromonosporales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR21617310_k127_1787834_0	1449126.JQKL01000061_gene1912	2.449e-291	915.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,267YZ@186813|unclassified Clostridiales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR21617310_k127_1787834_3	390989.JOEG01000004_gene3878	1.422e-11	70.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D9UB@85008|Micromonosporales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR21617310_k127_1787834_2	1003195.SCAT_2736	1.213e-39	149.0	COG4454@1|root,COG4454@2|Bacteria,2I9JP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
SRR21617310_k127_1789162_11	710111.FraQA3DRAFT_0556	6.255e-14	74.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR21617310_k127_1789162_5	656024.FsymDg_3902	1.188e-53	191.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR21617310_k127_1789162_4	909613.UO65_4141	1.024e-97	338.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4DZDJ@85010|Pseudonocardiales	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR21617310_k127_1789162_2	1121106.JQKB01000016_gene5271	3.734e-129	425.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,2JP8Z@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR21617310_k127_1789162_8	194439.CT0371	2.249e-43	170.0	COG0041@1|root,COG0041@2|Bacteria,1FDYI@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR21617310_k127_1789162_10	105420.BBPO01000008_gene2641	3.874e-14	81.0	COG2320@1|root,COG2320@2|Bacteria,2HG2U@201174|Actinobacteria,2NN9W@228398|Streptacidiphilus	201174|Actinobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR21617310_k127_1789162_3	1463855.JOHV01000107_gene95	7.871e-123	420.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the GarS family	purD	-	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR21617310_k127_1789162_1	1137268.AZXF01000036_gene3384	2.116e-174	557.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4EFS2@85012|Streptosporangiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR21617310_k127_1789162_6	1125863.JAFN01000001_gene1505	6.457e-51	198.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2WPAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_1789162_12	1385521.N803_07965	9.336e-06	58.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4FGZR@85021|Intrasporangiaceae	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
SRR21617310_k127_1789162_0	1297742.A176_02077	0.0	1081.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR21617310_k127_1789162_9	525909.Afer_1963	5.547e-29	123.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CN4Z@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR21617310_k127_1789162_7	1146883.BLASA_4678	1.618e-50	183.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4ERZT@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR21617310_k127_1798341_2	882083.SacmaDRAFT_4720	5.444e-58	219.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DYBQ@85010|Pseudonocardiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR21617310_k127_1798341_3	1299327.I546_5948	2e-23	102.0	28NDD@1|root,2ZBG6@2|Bacteria,2H1UZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1798341_1	1416759.AYMR01000009_gene2886	3.34e-96	321.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria,4FMT1@85023|Microbacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_1798341_0	710421.Mycch_1469	0.0	1290.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,232MQ@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_180478_8	936136.ARRT01000007_gene1278	4.472e-15	77.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
SRR21617310_k127_180478_2	1283299.AUKG01000002_gene4003	4.103e-78	268.0	COG1131@1|root,COG1131@2|Bacteria,2IJGC@201174|Actinobacteria,4CR8S@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR21617310_k127_180478_7	491916.RHECIAT_CH0002015	2.37e-16	91.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,4B785@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR21617310_k127_180478_6	298654.FraEuI1c_3662	4.216e-33	139.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR21617310_k127_180478_1	469383.Cwoe_5791	3.587e-89	306.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR21617310_k127_180478_4	1273125.Rrhod_1662	1.084e-50	186.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4G1YU@85025|Nocardiaceae	201174|Actinobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_180478_5	1125971.ASJB01000043_gene3222	3.201e-33	133.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,4E4RS@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR21617310_k127_180478_10	1146883.BLASA_2163	5.315e-06	56.0	2EM5W@1|root,33EV5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR21617310_k127_180478_3	1079986.JH164861_gene7150	9.615e-72	250.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR21617310_k127_180478_0	479434.Sthe_1230	1.673e-140	456.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR21617310_k127_180478_9	1283283.ATXA01000001_gene700	4.905e-13	70.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4ESTB@85013|Frankiales	201174|Actinobacteria	S	PFAM globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR21617310_k127_1806546_5	543632.JOJL01000017_gene9893	6.046e-41	161.0	COG1309@1|root,COG1309@2|Bacteria,2GPI5@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1806546_7	471852.Tcur_0667	7.392e-21	95.0	COG1309@1|root,COG1309@2|Bacteria,2GPI5@201174|Actinobacteria,4EK80@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1806546_3	543632.JOJL01000017_gene9892	1.316e-62	232.0	COG1131@1|root,COG1131@2|Bacteria,2IBP5@201174|Actinobacteria,4DIVM@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1806546_10	1293047.CBMA010000011_gene663	0.0005739	51.0	COG1131@1|root,arCOG00194@2157|Archaea,2XTCU@28890|Euryarchaeota,23SM1@183963|Halobacteria	183963|Halobacteria	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1806546_8	543632.JOJL01000017_gene9892	1.923e-06	54.0	COG1131@1|root,COG1131@2|Bacteria,2IBP5@201174|Actinobacteria,4DIVM@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1806546_2	543632.JOJL01000017_gene9891	2.218e-78	265.0	COG1277@1|root,COG1277@2|Bacteria,2IING@201174|Actinobacteria,4DGDD@85008|Micromonosporales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
SRR21617310_k127_1806546_0	106370.Francci3_2347	2.563e-88	303.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4ETNS@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase Tn3 family protein	tnpAC	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_1806546_9	1206733.BAGC01000041_gene1864	0.0001059	54.0	COG3386@1|root,COG3386@2|Bacteria,2I9Q3@201174|Actinobacteria,4G0W0@85025|Nocardiaceae	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1806546_4	1120936.KB907211_gene73	1.5e-49	184.0	COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria,4EQQY@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1806546_6	298653.Franean1_3535	7.593e-22	109.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,4EWBZ@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS4 family protein	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_1806546_1	1169161.KB897725_gene1733	4.568e-81	285.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria	201174|Actinobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR21617310_k127_1810427_1	222534.KB893670_gene3684	1.733e-175	555.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4ERNR@85013|Frankiales	201174|Actinobacteria	HP	PFAM UBA THIF-type NAD FAD binding	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR21617310_k127_1810427_3	500153.JOEK01000013_gene1772	1.527e-27	117.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	-	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR21617310_k127_1810427_0	469383.Cwoe_3251	2.614e-240	762.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR21617310_k127_1810427_2	1449347.JQLN01000004_gene6453	3.107e-137	469.0	COG2132@1|root,COG2132@2|Bacteria,2IDP7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
SRR21617310_k127_1811035_1	1454010.JEOE01000012_gene1620	3.412e-141	470.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4F10I@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR21617310_k127_1811035_2	404589.Anae109_4028	5.53e-94	316.0	COG3064@1|root,COG3064@2|Bacteria,1R7D3@1224|Proteobacteria,42Y44@68525|delta/epsilon subdivisions,2WT88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1811035_3	290397.Adeh_3593	1.674e-46	170.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR21617310_k127_1811035_0	290397.Adeh_3594	4.481e-267	833.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR21617310_k127_1812131_0	1463855.JOHV01000010_gene5531	1.002e-138	452.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR21617310_k127_1812131_1	298654.FraEuI1c_0065	2.48e-38	152.0	COG0454@1|root,COG2153@1|root,COG0456@2|Bacteria,COG2153@2|Bacteria	2|Bacteria	K	protein acetylation	yjcF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	ko:K02348,ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
SRR21617310_k127_1812131_2	1313172.YM304_08940	2.839e-30	132.0	COG1214@1|root,COG1214@2|Bacteria	2|Bacteria	O	tRNA threonylcarbamoyladenosine modification	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR21617310_k127_1818628_3	981369.JQMJ01000003_gene7725	3.879e-54	203.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,2NF3Z@228398|Streptacidiphilus	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR21617310_k127_1818628_0	1068980.ARVW01000001_gene6932	3.153e-161	523.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4E93P@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1818628_1	330084.JNYZ01000040_gene4941	7.923e-64	235.0	COG4262@1|root,COG4262@2|Bacteria,2GK2N@201174|Actinobacteria,4E784@85010|Pseudonocardiales	201174|Actinobacteria	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR21617310_k127_1818628_2	653045.Strvi_0760	1.097e-60	218.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
SRR21617310_k127_1818628_5	1172180.KB911775_gene6001	2.139e-34	136.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR21617310_k127_1818628_7	1173024.KI912148_gene3341	3.452e-25	111.0	COG1846@1|root,COG1846@2|Bacteria,1G6CB@1117|Cyanobacteria,1JJHC@1189|Stigonemataceae	1117|Cyanobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR21617310_k127_1818628_4	479435.Kfla_0523	6.231e-48	175.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4DUY6@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1818628_6	1463895.JODA01000018_gene6086	3.531e-31	131.0	COG3087@1|root,COG3087@2|Bacteria,2GNX9@201174|Actinobacteria	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1822360_0	1121377.KB906401_gene3526	1.785e-126	417.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_1822360_1	105425.BBPL01000071_gene3732	8.66e-90	310.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_1824340_0	1211815.CBYP010000014_gene3466	3.397e-82	284.0	COG4974@1|root,COG4974@2|Bacteria,2HTVG@201174|Actinobacteria,4EUVH@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_1824340_3	1123024.AUII01000028_gene2523	2.711e-15	80.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_1824340_2	1968.JOEV01000002_gene6931	2.994e-51	195.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_1824340_1	656024.FsymDg_1390	5.72e-61	216.0	COG3415@1|root,COG3415@2|Bacteria,2IJUQ@201174|Actinobacteria	201174|Actinobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR21617310_k127_1824340_6	1032480.MLP_08600	4.772e-06	53.0	COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria,4DVJE@85009|Propionibacteriales	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1824340_5	1299327.I546_1392	1.323e-06	60.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_1832676_0	1451189.CFAL_00755	6.286e-51	199.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,22JP8@1653|Corynebacteriaceae	201174|Actinobacteria	K	function transcriptional attenuator common domain protein	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_1832676_1	67352.JODS01000043_gene1123	3.063e-22	104.0	COG0318@1|root,COG0318@2|Bacteria,2GIX4@201174|Actinobacteria	201174|Actinobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_1832951_0	479434.Sthe_0078	4.581e-173	559.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1832951_2	326424.FRAAL5169	2.675e-37	149.0	COG1309@1|root,COG1309@2|Bacteria,2I9NV@201174|Actinobacteria,4EW00@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_1832951_1	263358.VAB18032_13940	3.2e-157	512.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DBH0@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl transferases group 1	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1832951_3	477641.MODMU_0510	3.333e-07	59.0	2E4WR@1|root,32ZQT@2|Bacteria,2GSGR@201174|Actinobacteria,4ETMI@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR21617310_k127_1836330_0	1288083.AUKR01000049_gene2037	4.638e-255	799.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_18422_22	644283.Micau_4238	6.417e-36	137.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,4D9V7@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR21617310_k127_18422_23	1148.1653503	1.083e-31	137.0	COG2214@1|root,COG2214@2|Bacteria,1GABC@1117|Cyanobacteria	1117|Cyanobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_18422_2	266117.Rxyl_2410	1.022e-272	853.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR21617310_k127_18422_4	266117.Rxyl_2411	1.801e-240	754.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR21617310_k127_18422_16	1157637.KB892091_gene5889	4.158e-86	297.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR21617310_k127_18422_6	710686.Mycsm_06334	1.619e-210	669.0	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria,23647@1762|Mycobacteriaceae	201174|Actinobacteria	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRR21617310_k127_18422_7	1298863.AUEP01000001_gene794	7.107e-196	619.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DNFG@85009|Propionibacteriales	201174|Actinobacteria	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR21617310_k127_18422_19	446470.Snas_5002	1.456e-69	252.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR21617310_k127_18422_5	525904.Tter_0160	8.035e-227	711.0	COG0277@1|root,COG0277@2|Bacteria,2NP2P@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
SRR21617310_k127_18422_3	867903.ThesuDRAFT_01477	4.894e-255	795.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,24Z0I@186801|Clostridia	186801|Clostridia	H	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR21617310_k127_18422_17	1128421.JAGA01000002_gene1529	3.449e-84	283.0	COG0259@1|root,COG0259@2|Bacteria,2NQT9@2323|unclassified Bacteria	2|Bacteria	H	Pfam:PNPOx_C	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
SRR21617310_k127_18422_8	1048339.KB913029_gene2528	5.343e-190	629.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_18422_13	471852.Tcur_2301	7.463e-106	349.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EH5C@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_18422_18	469383.Cwoe_3307	2.547e-73	258.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR21617310_k127_18422_11	479432.Sros_6513	2.672e-125	416.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4EQ0V@85012|Streptosporangiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
SRR21617310_k127_18422_25	1298863.AUEP01000006_gene3393	1.072e-12	76.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4DQUH@85009|Propionibacteriales	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03325,ko:K03741	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	LMWPc
SRR21617310_k127_18422_24	1122609.AUGT01000020_gene1021	4.894e-23	103.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4DSV5@85009|Propionibacteriales	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR21617310_k127_18422_21	1283287.KB822577_gene3103	6.103e-45	175.0	COG0586@1|root,COG0586@2|Bacteria,2GKKC@201174|Actinobacteria,4DSDT@85009|Propionibacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR21617310_k127_18422_20	548479.HMPREF0573_11669	4.727e-55	201.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4D3BN@85005|Actinomycetales	201174|Actinobacteria	T	Response regulator receiver domain protein	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR21617310_k127_18422_0	56110.Oscil6304_4177	0.0	1235.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	glsF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR21617310_k127_18422_14	1961.JOAK01000005_gene284	2.703e-105	359.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR21617310_k127_18422_10	1394178.AWOO02000049_gene6151	1.903e-140	454.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EFUR@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_18422_15	525909.Afer_0300	4.286e-94	332.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4CNME@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_18422_26	1713.JOFV01000005_gene2273	2.169e-10	68.0	COG0589@1|root,COG0589@2|Bacteria,2GUPR@201174|Actinobacteria,4F2S1@85016|Cellulomonadaceae	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR21617310_k127_18422_9	471852.Tcur_4898	4.067e-182	620.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4EHY6@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR21617310_k127_18422_1	1123322.KB904634_gene2414	1.325e-318	996.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR21617310_k127_18422_12	479433.Caci_2569	1.087e-107	378.0	COG0791@1|root,COG3292@1|root,COG0791@2|Bacteria,COG3292@2|Bacteria,2I4DW@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
SRR21617310_k127_184365_2	33898.JRHJ01000082_gene1688	3.632e-71	245.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR21617310_k127_184365_0	446462.Amir_6228	3.425e-163	521.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DXNR@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_184365_4	653045.Strvi_0559	7.441e-30	137.0	COG2208@1|root,COG2208@2|Bacteria,2GKDJ@201174|Actinobacteria	201174|Actinobacteria	KT	COG2208 Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR21617310_k127_184365_1	68170.KL590470_gene10813	1.872e-93	323.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4E1NM@85010|Pseudonocardiales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_184365_3	1169152.AXVD01000009_gene15	1.103e-70	269.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4FU5R@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
SRR21617310_k127_1848682_23	227882.SAV_634	7.795e-08	61.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_1848682_28	1343740.M271_38795	0.0002845	51.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_1848682_18	1380390.JIAT01000001_gene4997	1.127e-40	165.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR21617310_k127_1848682_19	585529.HMPREF0291_10351	1.049e-27	127.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,22JPX@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1848682_5	1123023.JIAI01000008_gene1594	1.064e-113	377.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DY3N@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR21617310_k127_1848682_15	644966.Tmar_1647	2.854e-66	241.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3WCJT@538999|Clostridiales incertae sedis	186801|Clostridia	P	permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR21617310_k127_1848682_12	204669.Acid345_2974	2.073e-71	261.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR21617310_k127_1848682_8	1254432.SCE1572_17935	5.913e-95	324.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2WMH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR21617310_k127_1848682_22	1116472.MGMO_7c00210	4.15e-15	76.0	COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria,1XGF9@135618|Methylococcales	135618|Methylococcales	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
SRR21617310_k127_1848682_17	583355.Caka_0325	7.201e-42	162.0	2EBAC@1|root,335AY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1848682_21	1056816.JAFQ01000004_gene1055	1.603e-15	91.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K20444,ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	AIDA,Exo_endo_phos,Glyco_trans_1_4,Glyco_transf_4,Hint_2
SRR21617310_k127_1848682_29	1125971.ASJB01000028_gene7803	0.0005664	51.0	2E0AE@1|root,32VXT@2|Bacteria,2ISP5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	S_layer_C
SRR21617310_k127_1848682_14	1123060.JONP01000008_gene4495	2.898e-69	243.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria,2TSMG@28211|Alphaproteobacteria,2JQ2V@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR21617310_k127_1848682_2	471852.Tcur_2622	2.615e-176	559.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4EHEK@85012|Streptosporangiales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR21617310_k127_1848682_13	1223523.H340_31605	3.968e-71	253.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR21617310_k127_1848682_0	1298880.AUEV01000002_gene1440	2.598e-182	586.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR21617310_k127_1848682_3	1120936.KB907209_gene1260	2.892e-154	499.0	COG0346@1|root,COG0346@2|Bacteria,2GKY9@201174|Actinobacteria,4EMCU@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	pheB	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR21617310_k127_1848682_16	1122611.KB903985_gene3623	1.163e-56	213.0	COG2084@1|root,COG2084@2|Bacteria,2ICA7@201174|Actinobacteria,4EP5N@85012|Streptosporangiales	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
SRR21617310_k127_1848682_9	1120936.KB907209_gene1262	2.464e-91	308.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4EJ9A@85012|Streptosporangiales	201174|Actinobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR21617310_k127_1848682_10	1382306.JNIM01000001_gene1609	1.086e-87	310.0	COG2120@1|root,COG2120@2|Bacteria,2G8FR@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	4.2.1.83	ko:K16515	ko00362,map00362	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	PIG-L
SRR21617310_k127_1848682_6	309801.trd_0903	6.201e-110	379.0	COG1099@1|root,COG1099@2|Bacteria,2GBCZ@200795|Chloroflexi,27YTV@189775|Thermomicrobia	189775|Thermomicrobia	S	with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1848682_20	1304865.JAGF01000001_gene68	1.733e-19	89.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR21617310_k127_1848682_27	1304865.JAGF01000001_gene68	8.035e-05	51.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR21617310_k127_1848682_11	1304865.JAGF01000001_gene68	8.278e-72	266.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR21617310_k127_1848682_7	1150864.MILUP08_44194	7.468e-100	331.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,4DDTD@85008|Micromonosporales	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_1848682_1	1463917.JODC01000007_gene7266	1.254e-179	568.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR21617310_k127_1848682_24	1463900.JOIX01000041_gene1975	1.42e-07	61.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR21617310_k127_1848682_4	66377.JOBH01000008_gene6686	6.126e-136	452.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_1848682_25	401053.AciPR4_2543	1.029e-06	52.0	COG0577@1|root,COG0577@2|Bacteria	401053.AciPR4_2543|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1849919_14	1348663.KCH_18540	2.745e-05	56.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2M05I@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR21617310_k127_1849919_0	235985.BBPN01000009_gene3820	3.142e-124	406.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2NERJ@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_1849919_8	1278073.MYSTI_04554	1.691e-28	123.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_1849919_10	1120950.KB892743_gene3128	1.286e-22	106.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4DNHJ@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1849919_3	28444.JODQ01000009_gene3693	2.017e-60	212.0	COG3945@1|root,COG3945@2|Bacteria,2I3V5@201174|Actinobacteria,4ER47@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_1849919_5	1283283.ATXA01000023_gene251	5.795e-41	155.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR21617310_k127_1849919_2	1120950.KB892746_gene3541	5.437e-69	238.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4DS49@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_1849919_4	1120950.KB892746_gene3542	4.777e-58	207.0	COG1846@1|root,COG1846@2|Bacteria,2II5E@201174|Actinobacteria,4DVTU@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_1849919_13	1304865.JAGF01000001_gene3351	5.56e-15	84.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_1849919_1	1304865.JAGF01000001_gene3350	3.237e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_1849919_11	106370.Francci3_2227	8.186e-20	93.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR21617310_k127_1849919_9	1223545.GS4_03_01050	1.583e-23	107.0	COG3467@1|root,COG3467@2|Bacteria,2ICSP@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR21617310_k127_1849919_6	1206744.BAGL01000128_gene6886	1.629e-34	150.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4G6WJ@85025|Nocardiaceae	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
SRR21617310_k127_1849919_7	33876.JNXY01000039_gene6685	3.131e-34	131.0	2DMB2@1|root,32UGJ@2|Bacteria,2I1VY@201174|Actinobacteria,4DKEK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1857712_2	1089549.AZUQ01000001_gene665	5.125e-47	183.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_1857712_1	469371.Tbis_2826	2.117e-158	513.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4DXVY@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR21617310_k127_1857712_0	767817.Desgi_2457	6.78e-168	561.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR21617310_k127_1857712_3	1120949.KB903356_gene8767	5.215e-24	106.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4DEPX@85008|Micromonosporales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR21617310_k127_1860592_18	1370120.AUWR01000011_gene1084	9.52e-16	76.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,233XN@1762|Mycobacteriaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR21617310_k127_1860592_17	479433.Caci_0897	4.778e-21	96.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR21617310_k127_1860592_6	1032480.MLP_32910	5.532e-71	250.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR21617310_k127_1860592_16	1123024.AUII01000051_gene646	1.05e-24	112.0	2FKM2@1|root,34C81@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1860592_1	1429046.RR21198_2648	6.41e-263	815.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4FZI8@85025|Nocardiaceae	201174|Actinobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR21617310_k127_1860592_22	1002340.AFCF01000062_gene690	0.0009553	51.0	COG2329@1|root,COG2329@2|Bacteria,1N1IT@1224|Proteobacteria,2UCHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_1860592_12	405948.SACE_6876	2.621e-44	168.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4E3JC@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR21617310_k127_1860592_15	469371.Tbis_0358	9.069e-27	121.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4E4UR@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR21617310_k127_1860592_13	1382306.JNIM01000001_gene1358	2.39e-38	161.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR21617310_k127_1860592_14	1229780.BN381_610018	8.353e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1860592_8	525904.Tter_0210	5.118e-66	239.0	COG2220@1|root,COG2220@2|Bacteria,2NPNQ@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	ulaG	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR21617310_k127_1860592_5	1122611.KB903941_gene2126	1.326e-94	344.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4EN64@85012|Streptosporangiales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR21617310_k127_1860592_3	1122611.KB903941_gene2127	1.432e-204	643.0	COG0119@1|root,COG0119@2|Bacteria,2INFJ@201174|Actinobacteria,4EMCZ@85012|Streptosporangiales	201174|Actinobacteria	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
SRR21617310_k127_1860592_19	1380356.JNIK01000018_gene683	7.713e-08	60.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4ETD5@85013|Frankiales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR21617310_k127_1860592_7	1449126.JQKL01000064_gene42	2.485e-68	237.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,26860@186813|unclassified Clostridiales	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR21617310_k127_1860592_9	471852.Tcur_4355	5.267e-64	222.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4EJ4N@85012|Streptosporangiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR21617310_k127_1860592_4	526225.Gobs_4523	1.549e-97	329.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4ERSC@85013|Frankiales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR21617310_k127_1860592_11	365528.KB891252_gene5608	4.738e-46	176.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4ESM1@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR21617310_k127_1860592_10	1120950.KB892746_gene3591	5.447e-50	184.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4DQS8@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR21617310_k127_1860592_0	656024.FsymDg_3971	0.0	1712.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4ES8S@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR21617310_k127_1860592_2	269800.Tfu_2653	5.347e-258	802.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4EG1N@85012|Streptosporangiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR21617310_k127_1864635_4	649831.L083_6324	6.489e-23	116.0	COG0577@1|root,COG0577@2|Bacteria,2HWDA@201174|Actinobacteria,4D9PY@85008|Micromonosporales	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1864635_2	383372.Rcas_3149	1.354e-60	237.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
SRR21617310_k127_1864635_3	1150864.MILUP08_41801	2.336e-49	191.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4D9ED@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1864635_1	1123023.JIAI01000021_gene2380	1.352e-119	395.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria,4EF6S@85010|Pseudonocardiales	201174|Actinobacteria	J	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
SRR21617310_k127_1864635_5	1869.MB27_02970	8.695e-19	101.0	COG0489@1|root,COG0489@2|Bacteria,2GJ1Y@201174|Actinobacteria,4DJGI@85008|Micromonosporales	201174|Actinobacteria	D	biosynthesis protein	-	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,ParA,Wzz
SRR21617310_k127_1864635_0	864702.OsccyDRAFT_4169	4.407e-168	551.0	COG4976@1|root,COG4976@2|Bacteria,1GQBZ@1117|Cyanobacteria,1HHY0@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR21617310_k127_1864635_6	272134.KB731324_gene1964	8.728e-05	52.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_1864787_7	485913.Krac_3380	2.491e-14	74.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
SRR21617310_k127_1864787_6	1463857.JOFZ01000009_gene6195	6.318e-19	90.0	COG5516@1|root,COG5516@2|Bacteria,2GKQZ@201174|Actinobacteria	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR21617310_k127_1864787_4	1312954.KI914877_gene1015	2.882e-19	89.0	2EK1R@1|root,33DS7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR21617310_k127_1864787_8	1123023.JIAI01000022_gene2306	1.828e-06	51.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_1864787_2	1449347.JQLN01000001_gene553	1.833e-71	252.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,2M302@2063|Kitasatospora	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1864787_5	1449347.JQLN01000001_gene369	2.924e-19	98.0	COG1277@1|root,COG1277@2|Bacteria,2I1PU@201174|Actinobacteria,2M4RN@2063|Kitasatospora	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR21617310_k127_1864787_3	1120936.KB907219_gene3176	4.543e-70	255.0	COG3878@1|root,COG3878@2|Bacteria,2GNAB@201174|Actinobacteria,4EJUV@85012|Streptosporangiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1864787_1	1120950.KB892752_gene6138	1.361e-72	249.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4DQP6@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_1864787_0	591167.Sfla_6521	4.116e-116	378.0	COG4974@1|root,COG4974@2|Bacteria,2IGPB@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_1868500_7	1906.SFRA_26615	9.005e-17	81.0	COG1553@1|root,COG1553@2|Bacteria,2IRB2@201174|Actinobacteria	201174|Actinobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
SRR21617310_k127_1868500_3	266117.Rxyl_2941	7.554e-72	250.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
SRR21617310_k127_1868500_1	40571.JOEA01000025_gene6030	3.064e-165	531.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4E0KC@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR21617310_k127_1868500_0	1123024.AUII01000010_gene684	1.147e-184	591.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,4E2F7@85010|Pseudonocardiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1868500_4	994479.GL877878_gene1554	2.048e-67	236.0	COG1309@1|root,COG1309@2|Bacteria,2IPAX@201174|Actinobacteria,4E51M@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_1868500_2	443218.AS9A_0814	1.147e-82	280.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,233G9@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_1877253_6	1120950.KB892763_gene5541	1.451e-132	432.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4DPYX@85009|Propionibacteriales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1877253_12	369723.Strop_2091	1.541e-104	347.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_1877253_5	675635.Psed_4154	2.756e-136	448.0	COG0044@1|root,COG0044@2|Bacteria	2|Bacteria	F	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR21617310_k127_1877253_2	675635.Psed_2321	6.332e-179	572.0	COG1879@1|root,COG1879@2|Bacteria,2GNSF@201174|Actinobacteria,4ECTV@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR21617310_k127_1877253_0	675635.Psed_4162	3.155e-194	625.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4EA8T@85010|Pseudonocardiales	201174|Actinobacteria	G	SMART ATPase, AAA type, core	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR21617310_k127_1877253_7	675635.Psed_4161	5.729e-127	415.0	COG1172@1|root,COG1172@2|Bacteria,2GMJW@201174|Actinobacteria,4EAQ2@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR21617310_k127_1877253_1	675635.Psed_2322	3.438e-181	592.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DZ1Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR21617310_k127_1877253_17	525368.HMPREF0591_1582	3.917e-78	271.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,235YB@1762|Mycobacteriaceae	201174|Actinobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR21617310_k127_1877253_20	797114.C475_21719	1.213e-76	274.0	COG0044@1|root,arCOG00689@2157|Archaea,2XV6W@28890|Euryarchaeota,23TP4@183963|Halobacteria	183963|Halobacteria	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	-	-	3.5.2.2,3.5.2.3	ko:K01464,ko:K01465	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046,M00051	R01993,R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR21617310_k127_1877253_13	675635.Psed_4160	1.447e-89	308.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR21617310_k127_1877253_18	675635.Psed_2323	2.079e-77	264.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4EB8B@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR21617310_k127_1877253_14	266117.Rxyl_2741	2.417e-82	290.0	COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria,4CQAH@84995|Rubrobacteria	84995|Rubrobacteria	EJ	Asparaginase glutaminase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR21617310_k127_1877253_3	1123023.JIAI01000003_gene2840	3.372e-162	526.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4E9FX@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR21617310_k127_1877253_10	1218075.BAYA01000028_gene5731	2.194e-118	413.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	-	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR21617310_k127_1877253_21	1218075.BAYA01000028_gene5732	4.24e-74	263.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,2VZ42@28216|Betaproteobacteria,1K8T8@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1877253_16	1218075.BAYA01000028_gene5733	9.382e-82	282.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2VHAJ@28216|Betaproteobacteria,1K63E@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_1877253_22	1117379.BABA_05421	5.5e-62	237.0	COG1414@1|root,COG1414@2|Bacteria,1W789@1239|Firmicutes,4ICFY@91061|Bacilli,1ZNGA@1386|Bacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR21617310_k127_1877253_8	1123319.AUBE01000014_gene5422	7.196e-121	399.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR21617310_k127_1877253_25	1128912.GMES_0354	2.942e-33	132.0	COG1917@1|root,COG1917@2|Bacteria,1N26Z@1224|Proteobacteria,1SEKQ@1236|Gammaproteobacteria,46C80@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_1877253_15	525368.HMPREF0591_0618	8.072e-82	298.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,2352P@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_1877253_26	479432.Sros_1790	5.709e-19	101.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria,4EKCD@85012|Streptosporangiales	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_1877253_23	656024.FsymDg_3902	2.887e-46	186.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR21617310_k127_1877253_11	326424.FRAAL4397	2.225e-116	419.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_1877253_9	1301098.PKB_3302	1.747e-118	398.0	COG0683@1|root,COG0683@2|Bacteria,1N0MT@1224|Proteobacteria	1224|Proteobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
SRR21617310_k127_1877253_19	1463820.JOGW01000005_gene3560	4.924e-77	274.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria	201174|Actinobacteria	Q	synthase	-	GO:0003674,GO:0003824,GO:0006582,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018958,GO:0019438,GO:0019748,GO:0042438,GO:0042440,GO:0044237,GO:0044249,GO:0044550,GO:0046148,GO:0046189,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.3.1.233	ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
SRR21617310_k127_1877253_4	1218075.BAYA01000028_gene5734	5.533e-152	492.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2VPWN@28216|Betaproteobacteria,1KAPB@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_1877253_24	479432.Sros_0612	7.295e-40	149.0	2C4HC@1|root,2Z9UU@2|Bacteria,2HV69@201174|Actinobacteria,4EP0U@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR21617310_k127_1877484_2	877455.Metbo_1665	1.987e-33	135.0	COG4832@1|root,arCOG03201@2157|Archaea,2Y3NU@28890|Euryarchaeota	28890|Euryarchaeota	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR21617310_k127_1877484_1	1121935.AQXX01000120_gene4828	6.092e-37	156.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,1RQ1B@1236|Gammaproteobacteria,1XM9K@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1877484_0	110319.CF8_4252	1.15e-44	166.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4DS5V@85009|Propionibacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR21617310_k127_1877484_5	479432.Sros_5190	1.828e-10	65.0	COG0406@1|root,COG0406@2|Bacteria,2GTM9@201174|Actinobacteria	201174|Actinobacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1877484_4	285535.JOEY01000062_gene9976	1.081e-18	95.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR21617310_k127_1877484_6	449447.MAE_01490	6.312e-09	57.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_1878585_1	512565.AMIS_34550	2.164e-43	162.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2ICGM@201174|Actinobacteria,4DDYE@85008|Micromonosporales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR21617310_k127_1878585_0	345341.KUTG_02457	1.218e-87	302.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,2ICCW@201174|Actinobacteria	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR21617310_k127_1879447_5	1206726.BAFV01000022_gene1592	1.409e-11	65.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4FVB1@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR21617310_k127_1879447_1	710111.FraQA3DRAFT_6081	1.266e-108	359.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR21617310_k127_1879447_4	1298863.AUEP01000007_gene386	1.711e-34	134.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR21617310_k127_1879447_2	1172181.KB911702_gene806	3.283e-72	253.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR21617310_k127_1879447_0	1121946.AUAX01000004_gene661	0.0	1682.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	1121946.AUAX01000004_gene661|-	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1879447_3	1121946.AUAX01000020_gene3198	4.677e-72	261.0	COG0791@1|root,COG3209@1|root,COG0791@2|Bacteria,COG3209@2|Bacteria,2I35N@201174|Actinobacteria,4DMW8@85008|Micromonosporales	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VCBS
SRR21617310_k127_1886144_0	266117.Rxyl_2839	5.182e-237	788.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CPP1@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_1886144_1	266117.Rxyl_2838	7.407e-198	635.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4CPPR@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_1886144_5	266117.Rxyl_2837	5.599e-72	259.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4CQAF@84995|Rubrobacteria	84995|Rubrobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_1886144_3	266117.Rxyl_2836	5.226e-120	393.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CQ7I@84995|Rubrobacteria	84995|Rubrobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_1886144_4	1068978.AMETH_1603	1.051e-81	289.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4DXWX@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR21617310_k127_1886144_6	1306174.JODP01000001_gene5189	2.492e-29	135.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	yedX	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR21617310_k127_1886144_2	1254432.SCE1572_35005	1.799e-163	528.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SRR21617310_k127_1890170_6	35754.JNYJ01000022_gene8164	6.237e-14	72.0	2DDSW@1|root,2ZJ4A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1890170_4	35754.JNYJ01000022_gene8165	7.119e-149	480.0	COG0304@1|root,COG0304@2|Bacteria,2GKV8@201174|Actinobacteria,4D9M7@85008|Micromonosporales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR21617310_k127_1890170_5	1463856.JOHY01000001_gene387	2.684e-42	163.0	COG0304@1|root,COG0304@2|Bacteria,2IR01@201174|Actinobacteria	201174|Actinobacteria	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
SRR21617310_k127_1890170_2	35754.JNYJ01000022_gene8168	3.04e-153	493.0	COG3185@1|root,COG3185@2|Bacteria,2GKG8@201174|Actinobacteria,4D9DA@85008|Micromonosporales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.46	ko:K16421	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06632	RC01471	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4,Glyoxalase_5
SRR21617310_k127_1890170_1	479435.Kfla_6065	4.046e-159	505.0	COG5285@1|root,COG5285@2|Bacteria,2GP77@201174|Actinobacteria,4DUA2@85009|Propionibacteriales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR21617310_k127_1890170_3	1121272.KB903249_gene2294	3.004e-150	481.0	COG1071@1|root,COG1071@2|Bacteria,2I3T8@201174|Actinobacteria,4DBX0@85008|Micromonosporales	201174|Actinobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_1890170_0	35754.JNYJ01000022_gene8172	7.298e-165	522.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DBSH@85008|Micromonosporales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_1890866_19	479431.Namu_4895	0.0009174	44.0	COG3842@1|root,COG3842@2|Bacteria,2H34R@201174|Actinobacteria,4EUMJ@85013|Frankiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR21617310_k127_1890866_6	1463917.JODC01000001_gene507	2.86e-87	313.0	COG0477@1|root,COG0477@2|Bacteria,2GMEJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	MFS_1,MFS_3,Patatin,Sugar_tr,cNMP_binding
SRR21617310_k127_1890866_5	644283.Micau_2703	2.404e-92	312.0	COG4424@1|root,COG4424@2|Bacteria,2HETZ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR21617310_k127_1890866_8	390989.JOEG01000004_gene4031	5.922e-80	276.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4DISI@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_1890866_10	1464048.JNZS01000004_gene1496	5.328e-58	213.0	2EW0P@1|root,33PE3@2|Bacteria,2I985@201174|Actinobacteria,4DITU@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1890866_2	68260.JOAY01000057_gene5337	2.648e-112	383.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria	201174|Actinobacteria	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR21617310_k127_1890866_4	68260.JOAY01000057_gene5336	1.048e-103	360.0	COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria	201174|Actinobacteria	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_1890866_16	1306990.BARG01000024_gene2375	1.973e-15	79.0	2APGC@1|root,31EJ6@2|Bacteria,2GWJ9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR21617310_k127_1890866_7	66373.JOFQ01000002_gene5172	9.409e-84	287.0	COG0189@1|root,COG0189@2|Bacteria,2HXBM@201174|Actinobacteria	201174|Actinobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK,TrkA_C
SRR21617310_k127_1890866_1	1306990.BARG01000024_gene2377	6.353e-139	463.0	COG0002@1|root,COG0002@2|Bacteria,2GKDU@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	-	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR21617310_k127_1890866_9	66373.JOFQ01000002_gene5202	5.998e-78	270.0	COG0548@1|root,COG0548@2|Bacteria,2GX9F@201174|Actinobacteria	201174|Actinobacteria	E	Amino acid kinase family	-	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR21617310_k127_1890866_3	285514.JNWO01000003_gene7086	6.98e-109	370.0	COG0624@1|root,COG0624@2|Bacteria,2IC2N@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family M20/M25/M40	-	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
SRR21617310_k127_1890866_0	1278073.MYSTI_01371	8.639e-171	552.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	aliA	-	6.2.1.26,6.2.1.3	ko:K00666,ko:K01897,ko:K01911,ko:K04116,ko:K18661	ko00061,ko00071,ko00130,ko00280,ko00362,ko01100,ko01110,ko01120,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00130,map00280,map00362,map01100,map01110,map01120,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00116,M00540	R01280,R03383,R04030,R05620	RC00004,RC00014,RC00137,RC01438	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_1890866_17	419947.MRA_0588	3.464e-10	63.0	2BT89@1|root,32NDN@2|Bacteria,2HDWZ@201174|Actinobacteria	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR21617310_k127_1890866_12	1415166.NONO_c54690	1.709e-31	130.0	COG2402@1|root,COG2402@2|Bacteria,2IFKB@201174|Actinobacteria,4G1N5@85025|Nocardiaceae	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR21617310_k127_1890866_18	649831.L083_1599	1.181e-06	53.0	COG5450@1|root,COG5450@2|Bacteria,2GXKD@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR21617310_k127_1890866_15	1961.JOAK01000039_gene4358	2.736e-22	102.0	COG1487@1|root,COG1487@2|Bacteria,2IJUM@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_1890866_14	439235.Dalk_4498	5.613e-23	115.0	COG1266@1|root,COG1266@2|Bacteria,1N67K@1224|Proteobacteria,42UUV@68525|delta/epsilon subdivisions,2WR6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR21617310_k127_1890866_11	748449.Halha_2023	4.324e-46	189.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,3WBTB@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS19835	UbiA
SRR21617310_k127_1890866_13	2002.JOEQ01000026_gene349	4.422e-28	132.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ3@201174|Actinobacteria	201174|Actinobacteria	C	PFAM luciferase-like	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR21617310_k127_1897504_4	1303518.CCALI_01870	1.436e-16	92.0	COG1341@1|root,COG1341@2|Bacteria	2|Bacteria	S	polynucleotide 5'-hydroxyl-kinase activity	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
SRR21617310_k127_1897504_3	67281.JNZZ01000030_gene3437	3.454e-48	191.0	2EBHZ@1|root,335IE@2|Bacteria,2GNMR@201174|Actinobacteria,417U6@629295|Streptomyces griseus group	201174|Actinobacteria	S	Phosphatase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	-	-	-	-	-	-	-	-	-	Phosphatase
SRR21617310_k127_1897504_0	28444.JODQ01000014_gene6728	1.207e-113	382.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR21617310_k127_1897504_1	479434.Sthe_1083	9.416e-81	284.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1897504_2	479434.Sthe_1082	3.141e-50	197.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR21617310_k127_1899110_0	1500890.JQNL01000001_gene3264	2.586e-26	113.0	2AT0I@1|root,31IGD@2|Bacteria,1NAE0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1909106_4	405948.SACE_4007	4.704e-81	285.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DZRW@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR21617310_k127_1909106_2	405948.SACE_4008	4.743e-127	421.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4DX73@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR21617310_k127_1909106_1	446462.Amir_3076	2.226e-184	605.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4DY9R@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,4.1.1.64	ko:K00596,ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR21617310_k127_1909106_0	446462.Amir_3077	2.253e-213	674.0	COG1012@1|root,COG1012@2|Bacteria,2HF1C@201174|Actinobacteria,4EA29@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR21617310_k127_1909106_3	477641.MODMU_2630	6.077e-92	327.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4ERF7@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 3	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR21617310_k127_1928868_1	1519464.HY22_08585	3.263e-98	353.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR21617310_k127_1928868_2	246197.MXAN_7270	1.564e-72	261.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR21617310_k127_1928868_0	1123504.JQKD01000010_gene2535	1.206e-118	391.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,4AA1C@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR21617310_k127_1928868_3	471852.Tcur_0588	4.365e-55	201.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4EGZ9@85012|Streptosporangiales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR21617310_k127_1932838_3	869210.Marky_1031	4.421e-50	185.0	COG0500@1|root,COG2226@2|Bacteria,1WKNC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_1932838_6	1206729.BAFZ01000089_gene2329	0.0004016	49.0	COG3631@1|root,COG3631@2|Bacteria,2GUCG@201174|Actinobacteria,4FV8K@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_1932838_5	1127134.NOCYR_2426	3.83e-07	61.0	COG0596@1|root,COG0596@2|Bacteria,2HHVH@201174|Actinobacteria,4G10D@85025|Nocardiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_1932838_2	1131730.BAVI_05739	1.247e-57	211.0	COG4671@1|root,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR21617310_k127_1932838_4	1312954.KI914854_gene2476	7.124e-21	106.0	COG0477@1|root,COG2814@2|Bacteria,2GM0Q@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_1932838_1	1173023.KE650771_gene1224	2.369e-180	576.0	COG1785@1|root,COG1785@2|Bacteria,1G4BJ@1117|Cyanobacteria	1117|Cyanobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR21617310_k127_1932838_0	1449353.JQMQ01000005_gene590	3.011e-186	595.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,2NHHA@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1932838_8	446468.Ndas_1232	0.0005959	50.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria,4EGH0@85012|Streptosporangiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR21617310_k127_1932838_7	1394178.AWOO02000032_gene4930	0.0005464	46.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4EGSU@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_1933006_1	1128421.JAGA01000002_gene331	5.812e-208	681.0	COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR21617310_k127_1933006_8	298653.Franean1_6445	4.486e-49	192.0	COG0723@1|root,COG0723@2|Bacteria,2I2RI@201174|Actinobacteria,4EUMX@85013|Frankiales	201174|Actinobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1933006_3	263358.VAB18032_23365	3.966e-130	443.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR21617310_k127_1933006_7	68570.DC74_6663	1.248e-59	215.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR21617310_k127_1933006_4	1128421.JAGA01000002_gene1693	7.1e-127	429.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1933006_5	1128421.JAGA01000002_gene1692	3.009e-97	332.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR21617310_k127_1933006_6	1128421.JAGA01000002_gene1691	7.279e-84	298.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR21617310_k127_1933006_0	335543.Sfum_3546	2.916e-316	990.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
SRR21617310_k127_1933006_2	251229.Chro_0877	7.41e-193	625.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_1933006_9	251229.Chro_0878	5.695e-06	58.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	strN	-	2.7.1.72,2.7.1.89	ko:K04343,ko:K07251,ko:K18844	ko00730,ko01100,map00730,map01100	M00766	R02134,R02225	RC00002,RC00017,RC00078	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	APH,Choline_kinase
SRR21617310_k127_1933603_0	457429.ABJI02000833_gene2526	1.015e-123	410.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria	201174|Actinobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
SRR21617310_k127_1933603_3	1380347.JNII01000011_gene1034	2.666e-85	299.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR21617310_k127_1933603_2	471852.Tcur_2334	1.998e-120	402.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EHUD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_1933603_1	926560.KE387023_gene2481	8.673e-121	400.0	COG0667@1|root,COG0667@2|Bacteria,1WM4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_1933603_4	1536775.H70737_04090	0.0009593	44.0	COG0640@1|root,COG0640@2|Bacteria,1V1HY@1239|Firmicutes,4HG51@91061|Bacilli,26RZX@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR21617310_k127_1936895_7	208444.JNYY01000024_gene455	6.446e-05	47.0	COG3173@1|root,COG3173@2|Bacteria,2I52T@201174|Actinobacteria,4E36U@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR21617310_k127_1936895_4	2002.JOEQ01000061_gene7192	1.339e-20	92.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR21617310_k127_1936895_3	1121272.KB903283_gene5282	3.971e-37	153.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	-	2.7.1.25,2.7.3.13,2.7.7.4	ko:K00860,ko:K00958,ko:K22424	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR21617310_k127_1936895_5	298655.KI912266_gene1630	1.862e-07	54.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria,4EVT6@85013|Frankiales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
SRR21617310_k127_1936895_1	543632.JOJL01000019_gene10100	6.349e-73	255.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR21617310_k127_1936895_6	926560.KE387023_gene1626	2.251e-06	55.0	2DI4N@1|root,3020X@2|Bacteria,1WKTX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR21617310_k127_1936895_0	1304865.JAGF01000001_gene77	9.668e-76	263.0	COG1595@1|root,COG1595@2|Bacteria,2GTCV@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR21617310_k127_1936895_2	1122611.KB903939_gene520	1.383e-64	239.0	COG0657@1|root,COG0657@2|Bacteria,2I3E3@201174|Actinobacteria,4ER9H@85012|Streptosporangiales	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1939623_2	1120950.KB892707_gene4609	1.067e-21	109.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR21617310_k127_1939623_0	1089553.Tph_c16510	4.994e-95	329.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR21617310_k127_1939623_1	1229780.BN381_90073	1.285e-86	291.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR21617310_k127_1941277_5	1254432.SCE1572_17840	3.809e-12	79.0	2BCR5@1|root,326BM@2|Bacteria,1QAS5@1224|Proteobacteria,43E3F@68525|delta/epsilon subdivisions,2WZKS@28221|Deltaproteobacteria,2Z2BX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1941277_0	290397.Adeh_2766	7.953e-146	486.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR21617310_k127_1941277_2	1297742.A176_07615	5.785e-53	194.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR21617310_k127_1941277_1	595460.RRSWK_06979	4.157e-73	252.0	COG0381@1|root,COG0381@2|Bacteria,2IWR6@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR21617310_k127_194199_2	1049564.TevJSym_ac01750	3.171e-36	138.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR21617310_k127_194199_0	1121946.AUAX01000035_gene6147	4.056e-132	430.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4D9RI@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_194199_1	1112204.GPOL_c02910	1.95e-43	165.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4GE90@85026|Gordoniaceae	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
SRR21617310_k127_1949387_16	526225.Gobs_0634	1.174e-34	142.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4ERDS@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR21617310_k127_1949387_9	1463887.KL589954_gene7130	2.714e-72	254.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR21617310_k127_1949387_8	1121468.AUBR01000035_gene1403	1.098e-86	294.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,42FD2@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR21617310_k127_1949387_3	471852.Tcur_4482	2.526e-152	496.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4EIAD@85012|Streptosporangiales	201174|Actinobacteria	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR21617310_k127_1949387_0	1123320.KB889585_gene1820	0.0	1340.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_1949387_13	452652.KSE_44360	9.968e-52	200.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,2M1CK@2063|Kitasatospora	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1949387_10	1128421.JAGA01000002_gene614	1.333e-61	234.0	COG1194@1|root,COG1194@2|Bacteria,2NPAU@2323|unclassified Bacteria	2|Bacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR21617310_k127_1949387_5	1120950.KB892801_gene1750	9.174e-144	471.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DNF3@85009|Propionibacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR21617310_k127_1949387_7	1229203.KI301992_gene120	6.657e-107	363.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,3UX2J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DisA bacterial checkpoint controller nucleotide-binding	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR21617310_k127_1949387_12	1114959.SZMC14600_13805	3.992e-52	188.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4DXYN@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR21617310_k127_1949387_17	309801.trd_1724	5.774e-33	139.0	COG1211@1|root,COG1211@2|Bacteria,2G6UP@200795|Chloroflexi,27Y9J@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR21617310_k127_1949387_14	292459.STH3122	7.567e-46	176.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR21617310_k127_1949387_6	1121468.AUBR01000007_gene250	2.753e-132	438.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,42F0R@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR21617310_k127_1949387_11	401053.AciPR4_3545	1.314e-55	211.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria,2JII0@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR21617310_k127_1949387_15	1869.MB27_23830	3.051e-39	153.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_1949387_4	106370.Francci3_2428	1.203e-149	485.0	COG2079@1|root,COG2079@2|Bacteria,2HRSH@201174|Actinobacteria,4EVTT@85013|Frankiales	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR21617310_k127_1949387_2	1476876.JOJO01000041_gene8135	1.305e-170	561.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR21617310_k127_1949387_1	675635.Psed_3670	6.585e-198	647.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DZT1@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE3_2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_1949387_18	1121447.JONL01000001_gene735	3.259e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1957268_6	1380346.JNIH01000018_gene5303	1.444e-44	166.0	COG1487@1|root,COG1487@2|Bacteria,2IGMY@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_1957268_8	68170.KL590511_gene2969	2.369e-38	145.0	COG4118@1|root,COG4118@2|Bacteria,2IS4Y@201174|Actinobacteria,4E6PB@85010|Pseudonocardiales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR21617310_k127_1957268_5	1089545.KB913037_gene3461	9.649e-55	218.0	28MW8@1|root,2ZB3I@2|Bacteria,2HMUE@201174|Actinobacteria,4E4SC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1957268_11	1122919.KB905654_gene3700	2.145e-17	97.0	2DBFE@1|root,2Z8XI@2|Bacteria,1V2DW@1239|Firmicutes,4HGDP@91061|Bacilli,272DC@186822|Paenibacillaceae	91061|Bacilli	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_1957268_10	1121017.AUFG01000035_gene693	2.124e-17	83.0	2DPHS@1|root,3324E@2|Bacteria,2GT39@201174|Actinobacteria,4FHUC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1957268_7	710686.Mycsm_00854	4.139e-39	155.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,239XI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_1957268_9	315730.BcerKBAB4_2368	2.676e-34	138.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,4IPVZ@91061|Bacilli,1ZRDW@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_1957268_2	272560.BPSS1911	1.78e-117	396.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
SRR21617310_k127_1957268_4	1120953.AUBH01000004_gene3093	6.819e-100	346.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRR21617310_k127_1957268_1	1449976.KALB_1044	1.4e-150	481.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJX@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_1957268_3	1120950.KB892708_gene4387	1.373e-115	380.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DP1X@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_1957268_0	749414.SBI_05548	0.0	1392.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR21617310_k127_1957268_12	1382359.JIAL01000001_gene2173	2.199e-06	53.0	COG2764@1|root,COG2764@2|Bacteria,3Y4WV@57723|Acidobacteria,2JK5P@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_1961756_6	1120949.KB903311_gene793	1.28e-14	84.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR21617310_k127_1961756_4	479434.Sthe_1646	1.692e-63	228.0	COG1733@1|root,COG3255@1|root,COG1733@2|Bacteria,COG3255@2|Bacteria,2G9M1@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR21617310_k127_1961756_1	2002.JOEQ01000024_gene215	2.319e-198	630.0	COG0174@1|root,COG0174@2|Bacteria,2GJ83@201174|Actinobacteria,4ENPD@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
SRR21617310_k127_1961756_0	710686.Mycsm_00808	1.765e-212	671.0	COG0531@1|root,COG0531@2|Bacteria,2HMMA@201174|Actinobacteria,23621@1762|Mycobacteriaceae	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_1961756_5	1382356.JQMP01000003_gene2130	1.978e-58	218.0	COG2159@1|root,COG2159@2|Bacteria,2G6EZ@200795|Chloroflexi,27YN4@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR21617310_k127_1961756_2	1313172.YM304_25950	2.997e-177	586.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR21617310_k127_1961756_3	882083.SacmaDRAFT_2133	4.956e-66	234.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DYC5@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
SRR21617310_k127_1962080_2	35754.JNYJ01000016_gene9394	2.695e-31	136.0	COG1670@1|root,COG1670@2|Bacteria,2I1T2@201174|Actinobacteria,4DK8Y@85008|Micromonosporales	201174|Actinobacteria	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1962080_0	557599.MKAN_21845	2.532e-82	299.0	COG4974@1|root,COG4974@2|Bacteria,2HZZ8@201174|Actinobacteria,232YS@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1962080_3	710687.KI912270_gene6641	2.15e-21	111.0	COG4974@1|root,COG4974@2|Bacteria,2HZZ8@201174|Actinobacteria,232YS@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1962080_4	1961.JOAK01000022_gene7003	1.775e-11	69.0	COG3655@1|root,COG3655@2|Bacteria,2ISZ0@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
SRR21617310_k127_1962080_1	262316.MAP_0106c	2.069e-45	173.0	COG4974@1|root,COG4974@2|Bacteria,2IC5F@201174|Actinobacteria,2335J@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_1965557_7	1380390.JIAT01000012_gene3005	2.687e-36	146.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR21617310_k127_1965557_4	1380390.JIAT01000012_gene3001	2.141e-55	209.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR21617310_k127_1965557_11	1380390.JIAT01000012_gene3004	6.838e-18	96.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
SRR21617310_k127_1965557_0	1192034.CAP_5178	1.345e-197	632.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR21617310_k127_1965557_2	1961.JOAK01000001_gene3385	7.569e-89	309.0	COG2211@1|root,COG2211@2|Bacteria,2HH59@201174|Actinobacteria	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_1965557_1	66874.JOFS01000018_gene3698	7.042e-100	334.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR21617310_k127_1965557_9	1463825.JNXC01000008_gene1163	1.075e-26	113.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR21617310_k127_1965557_3	1051632.TPY_0086	5.161e-58	212.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24KJU@186801|Clostridia	186801|Clostridia	M	acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR21617310_k127_1965557_8	749927.AMED_0757	1.044e-33	133.0	COG0640@1|root,COG0640@2|Bacteria,2IMCE@201174|Actinobacteria,4EC5P@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR21617310_k127_1965557_10	675635.Psed_5309	3.994e-21	100.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DXFV@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pkaI	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Septum_form
SRR21617310_k127_1965557_12	1214101.BN159_4295	1.46e-07	55.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR21617310_k127_1965557_5	675635.Psed_4176	1.37e-54	202.0	COG1802@1|root,COG1802@2|Bacteria,2INWR@201174|Actinobacteria,4EBUI@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_1966651_0	2002.JOEQ01000072_gene6628	1.747e-104	350.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_1966651_1	928724.SacglDRAFT_01990	4.343e-87	295.0	COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria,4E35N@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR21617310_k127_1966651_2	1120934.KB894416_gene4043	3.497e-80	272.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4E1BA@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_1969564_2	1120950.KB892819_gene7157	2.702e-35	137.0	2E5N2@1|root,330CX@2|Bacteria,2GUMX@201174|Actinobacteria,4DWAJ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1969564_1	479434.Sthe_0896	1.748e-45	180.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR21617310_k127_1969564_3	405948.SACE_4917	8.016e-24	106.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_1969564_0	66377.JOBH01000003_gene5239	1.216e-149	505.0	COG0507@1|root,COG1112@1|root,COG4249@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559,Peptidase_C14
SRR21617310_k127_1972547_0	247490.KSU1_D0507	0.0	1478.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1972547_1	351607.Acel_0173	2.369e-66	239.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4ET4R@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR21617310_k127_1981236_0	287.DR97_4860	3.053e-42	164.0	COG0412@1|root,COG0412@2|Bacteria,1QTUP@1224|Proteobacteria,1SUU1@1236|Gammaproteobacteria,1YHC7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
SRR21617310_k127_1981236_1	4950.XP_003680047.1	1.92e-05	55.0	COG1956@1|root,2RXXR@2759|Eukaryota,3A0D1@33154|Opisthokonta,3P1WW@4751|Fungi,3QU2E@4890|Ascomycota,3RU7K@4891|Saccharomycetes,3S0YR@4893|Saccharomycetaceae	4751|Fungi	T	Saccharomyces cerevisiae YKL069W	YKL069W	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0033554,GO:0034599,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070191,GO:0070887	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
SRR21617310_k127_1981236_2	485913.Krac_5089	4.733e-05	48.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_1981236_3	1122611.KB903943_gene1543	0.0009359	48.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4EK91@85012|Streptosporangiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_1982197_4	1123322.KB904671_gene2850	2.471e-92	305.0	COG0491@1|root,COG0491@2|Bacteria,2I9IC@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_1982197_8	797299.HALLA_01610	8.222e-20	98.0	COG0262@1|root,arCOG01490@2157|Archaea,2XXBJ@28890|Euryarchaeota,23VPE@183963|Halobacteria	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_1982197_3	479431.Namu_3576	7.829e-106	347.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4ETST@85013|Frankiales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR21617310_k127_1982197_7	1304865.JAGF01000001_gene2110	5.693e-35	153.0	2EXM2@1|root,33QWZ@2|Bacteria,2IEZ2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1982197_6	1306990.BARG01000090_gene8972	3.278e-42	170.0	2EXM2@1|root,33QWZ@2|Bacteria,2IEZ2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1982197_1	644283.Micau_2646	1.463e-270	857.0	COG3208@1|root,COG3208@2|Bacteria,2I5FS@201174|Actinobacteria,4DMNR@85008|Micromonosporales	201174|Actinobacteria	Q	Lantibiotic dehydratase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lant_dehydr_N,Thioesterase
SRR21617310_k127_1982197_2	644283.Micau_2640	9.712e-146	488.0	COG1020@1|root,COG1020@2|Bacteria,2GQF8@201174|Actinobacteria,4DHQ9@85008|Micromonosporales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR21617310_k127_1982197_0	479432.Sros_2420	0.0	1992.0	COG0477@1|root,COG1020@1|root,COG0477@2|Bacteria,COG1020@2|Bacteria,2H65N@201174|Actinobacteria,4EN1P@85012|Streptosporangiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR21617310_k127_1982197_5	68570.DC74_964	6.256e-86	293.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_1983491_11	487521.OCU_42800	1.259e-15	90.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR21617310_k127_1983491_10	485913.Krac_8476	7.163e-16	91.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR21617310_k127_1983491_8	1173027.Mic7113_1015	1.513e-23	106.0	COG4454@1|root,COG4454@2|Bacteria,1G83X@1117|Cyanobacteria	1117|Cyanobacteria	P	Sulfocyanin (SoxE) domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,SoxE
SRR21617310_k127_1983491_6	402881.Plav_1134	1.177e-52	193.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,1JPFB@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_1983491_7	869210.Marky_0355	9.056e-28	130.0	COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
SRR21617310_k127_1983491_0	1463917.JODC01000021_gene9127	2.972e-195	632.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_1983491_4	1449353.JQMQ01000005_gene3595	9.414e-93	311.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,2NGR9@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_1983491_5	1449346.JQMO01000003_gene5278	2.133e-74	258.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,2M1CI@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_1983491_1	457429.ABJI02000741_gene338	3.123e-166	539.0	COG0654@1|root,COG2072@1|root,COG0654@2|Bacteria,COG2072@2|Bacteria,2GK95@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	arsO	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR21617310_k127_1983491_13	67332.FM21_13635	0.0001373	48.0	COG3639@1|root,COG3639@2|Bacteria,2IAPI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type phosphate phosphonate transport system permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR21617310_k127_1983491_9	675635.Psed_1952	4.836e-16	85.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4E3RM@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_1983491_2	749414.SBI_02594	5.56e-116	382.0	COG0331@1|root,COG0331@2|Bacteria	2|Bacteria	I	[acyl-carrier-protein] S-malonyltransferase activity	-	-	2.3.1.39	ko:K00645,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1,NMO
SRR21617310_k127_1983491_3	105422.BBPM01000128_gene1904	2.607e-113	374.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR21617310_k127_198739_2	485913.Krac_3320	4.085e-16	81.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_198739_3	67315.JOBD01000022_gene132	0.0001865	53.0	2DKWW@1|root,30NAT@2|Bacteria,2GKYJ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR21617310_k127_198739_1	909613.UO65_0151	1.715e-17	83.0	COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria,4DYQP@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR21617310_k127_198739_0	1463825.JNXC01000019_gene6501	2.438e-70	249.0	COG2304@1|root,COG2304@2|Bacteria,2HR55@201174|Actinobacteria,4DXBI@85010|Pseudonocardiales	201174|Actinobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
SRR21617310_k127_1987787_17	1232410.KI421424_gene1621	3.98e-08	62.0	COG1618@1|root,COG1618@2|Bacteria,1R0HW@1224|Proteobacteria	1224|Proteobacteria	F	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR21617310_k127_1987787_4	797304.Natgr_2268	5.492e-59	228.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR21617310_k127_1987787_0	66429.JOFL01000028_gene5044	9.84e-192	617.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR21617310_k127_1987787_1	247490.KSU1_D0235	2.099e-98	338.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR21617310_k127_1987787_2	272123.Anacy_1118	7.588e-90	315.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1HIYE@1161|Nostocales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_1987787_3	67356.KL575644_gene1933	1.252e-69	253.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_1987787_9	105422.BBPM01000082_gene165	9.309e-31	141.0	COG2244@1|root,COG2244@2|Bacteria,2HRUW@201174|Actinobacteria,2NKCF@228398|Streptacidiphilus	201174|Actinobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR21617310_k127_1987787_5	313590.MED134_13686	2.272e-56	209.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia,37DUM@326319|Dokdonia	976|Bacteroidetes	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR21617310_k127_1987787_8	395961.Cyan7425_3802	1.745e-36	151.0	COG0457@1|root,COG0457@2|Bacteria,1G2CI@1117|Cyanobacteria,3KIEC@43988|Cyanothece	1117|Cyanobacteria	H	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR21617310_k127_1987787_15	867903.ThesuDRAFT_01904	1.033e-12	78.0	COG0558@1|root,COG0558@2|Bacteria,1VFFA@1239|Firmicutes	1239|Firmicutes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRR21617310_k127_1987787_12	1068980.ARVW01000001_gene6443	1.207e-18	100.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4E10J@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_1987787_6	1414720.CBYM010000031_gene2024	5.747e-40	158.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36G3D@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
SRR21617310_k127_1987787_14	235985.BBPN01000009_gene3723	6.304e-16	92.0	2E2EJ@1|root,32XJ3@2|Bacteria,2ISI6@201174|Actinobacteria,2NKMK@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR21617310_k127_1987787_11	999611.KI421505_gene4080	1.173e-18	100.0	COG0125@1|root,COG0125@2|Bacteria,1Q8K6@1224|Proteobacteria,2UWPB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1987787_13	477641.MODMU_4433	1.024e-17	93.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR21617310_k127_1987787_10	883103.HMPREF9703_00680	4.197e-23	109.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,27FNN@186828|Carnobacteriaceae	91061|Bacilli	T	helix_turn_helix, Lux Regulon	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR21617310_k127_1987787_7	1380390.JIAT01000010_gene4354	1.058e-37	153.0	COG1409@1|root,COG1409@2|Bacteria,2GVVJ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR21617310_k127_1990421_0	710696.Intca_0155	3.901e-73	258.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4FHJZ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
SRR21617310_k127_1990421_2	604331.AUHY01000005_gene808	7.352e-14	78.0	COG0589@1|root,COG0589@2|Bacteria,1WJW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR21617310_k127_1990421_3	1240349.ANGC01000002_gene2261	7.996e-13	79.0	2BKDI@1|root,32EU7@2|Bacteria,2HJMF@201174|Actinobacteria,4G71C@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_1990421_4	1957.JODX01000014_gene1054	0.0001038	51.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR21617310_k127_1990421_1	1246995.AFR_03395	6.187e-23	100.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4D92K@85008|Micromonosporales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR21617310_k127_1997772_2	543632.JOJL01000038_gene3107	1.092e-21	103.0	COG1309@1|root,COG1309@2|Bacteria,2I8MS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR21617310_k127_1997772_0	469383.Cwoe_3624	3.823e-131	448.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR21617310_k127_1997772_1	196162.Noca_3341	3.552e-67	239.0	COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria	201174|Actinobacteria	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR21617310_k127_2000598_7	465515.Mlut_17790	9.235e-25	109.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7XA@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_2000598_2	1232410.KI421428_gene1110	4.04e-124	405.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,43T7Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_2000598_3	867903.ThesuDRAFT_01196	2.495e-95	323.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia	186801|Clostridia	C	dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_2000598_9	1122138.AQUZ01000001_gene1482	0.0001163	49.0	COG0477@1|root,COG0477@2|Bacteria,2GMFC@201174|Actinobacteria,4DWNQ@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2000598_6	1157640.AQWO01000005_gene2172	8.789e-25	107.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
SRR21617310_k127_2000598_4	1206726.BAFV01000053_gene3733	1.131e-42	170.0	COG0789@1|root,COG0789@2|Bacteria,2IKRG@201174|Actinobacteria,4G2KE@85025|Nocardiaceae	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR21617310_k127_2000598_8	253839.SSNG_04770	1.184e-20	101.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_2000598_1	1121946.AUAX01000046_gene7466	1.012e-133	443.0	COG0531@1|root,COG0531@2|Bacteria,2IAK1@201174|Actinobacteria,4DBK2@85008|Micromonosporales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
SRR21617310_k127_2000598_5	1123320.KB889664_gene1042	1.862e-35	140.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_2000598_0	479434.Sthe_3293	9.956e-199	636.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_2004383_22	345341.KUTG_05605	6.767e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,2GUGU@201174|Actinobacteria,4E8EB@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2004383_12	1906.SFRA_07320	1.208e-50	191.0	COG0863@1|root,COG0863@2|Bacteria,2I9A6@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR21617310_k127_2004383_23	525268.HMPREF0308_2509	1.182e-07	59.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,22JSW@1653|Corynebacteriaceae	201174|Actinobacteria	L	Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2004383_9	1121946.AUAX01000001_gene2420	1.275e-64	238.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4DM0R@85008|Micromonosporales	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2004383_27	1120949.KB903357_gene4799	4.7e-05	50.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria,4DCBF@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_S8
SRR21617310_k127_2004383_17	1306174.JODP01000018_gene4396	1.032e-29	124.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_S8
SRR21617310_k127_2004383_24	469371.Tbis_1460	7.169e-07	56.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria,4E11B@85010|Pseudonocardiales	201174|Actinobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_S8
SRR21617310_k127_2004383_3	471852.Tcur_1863	3.609e-147	487.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4EH2B@85012|Streptosporangiales	201174|Actinobacteria	P	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR21617310_k127_2004383_14	365528.KB891252_gene5510	4.285e-39	160.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4ESJ8@85013|Frankiales	201174|Actinobacteria	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR21617310_k127_2004383_4	867903.ThesuDRAFT_00304	1.043e-141	461.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR21617310_k127_2004383_19	937777.Deipe_1100	1.351e-14	79.0	COG0236@1|root,COG0236@2|Bacteria,1WKP9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR21617310_k127_2004383_7	525903.Taci_1097	1.194e-71	256.0	COG1028@1|root,COG1028@2|Bacteria,3TAAZ@508458|Synergistetes	508458|Synergistetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_2004383_5	429009.Adeg_0956	4.811e-107	359.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR21617310_k127_2004383_8	1430331.EP10_16805	1.896e-66	242.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1WERG@129337|Geobacillus	91061|Bacilli	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR21617310_k127_2004383_25	1223543.GP2_033_00800	1.273e-06	60.0	COG4963@1|root,COG4963@2|Bacteria,2I2PT@201174|Actinobacteria,4GA6N@85026|Gordoniaceae	201174|Actinobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2004383_6	526225.Gobs_0592	1.673e-82	304.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERPD@85013|Frankiales	201174|Actinobacteria	U	PFAM Type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR21617310_k127_2004383_28	568706.BN118_1939	0.0001257	55.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2VJ80@28216|Betaproteobacteria,3T3KX@506|Alcaligenaceae	28216|Betaproteobacteria	U	Type II secretion system protein F domain-containing protein 1	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_2004383_21	1120950.KB892762_gene5459	3.491e-10	72.0	COG2064@1|root,COG2064@2|Bacteria,2IQE9@201174|Actinobacteria,4DRRD@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_2004383_26	1122609.AUGT01000010_gene3807	2.535e-06	57.0	2EGB2@1|root,33A2X@2|Bacteria,2HZDA@201174|Actinobacteria,4DS7Y@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR21617310_k127_2004383_15	710111.FraQA3DRAFT_2691	6.327e-35	153.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR21617310_k127_2004383_0	219305.MCAG_03225	9.404e-261	828.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4D8Z2@85008|Micromonosporales	201174|Actinobacteria	L	DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR21617310_k127_2004383_16	1120936.KB907213_gene4861	4.177e-31	139.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4EIUY@85012|Streptosporangiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_2004383_13	1223523.H340_04099	1.409e-50	184.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR21617310_k127_2004383_20	1123321.KB905819_gene5926	2.816e-14	83.0	COG2172@1|root,COG2172@2|Bacteria,2IHNR@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR21617310_k127_2004383_1	469371.Tbis_0223	2.059e-259	824.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4DY9J@85010|Pseudonocardiales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR21617310_k127_2004383_2	986075.CathTA2_1976	4.898e-205	662.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR21617310_k127_2004383_10	1121377.KB906404_gene2906	1.606e-57	217.0	COG0125@1|root,COG0125@2|Bacteria,1WK3U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR21617310_k127_2004383_11	1146883.BLASA_0569	1.145e-55	214.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4ESBK@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III, delta'	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR21617310_k127_2004383_18	1120950.KB892790_gene2056	1.837e-22	104.0	COG0582@1|root,COG0582@2|Bacteria,2I9QS@201174|Actinobacteria,4DTV4@85009|Propionibacteriales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR21617310_k127_200586_0	1120983.KB894571_gene2480	1.078e-209	663.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,1JPCC@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR21617310_k127_200586_1	2002.JOEQ01000006_gene1492	1.829e-147	478.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4EN0M@85012|Streptosporangiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_200586_2	298655.KI912266_gene6564	1.213e-146	471.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4ESZR@85013|Frankiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR21617310_k127_200586_3	1089545.KB913037_gene6391	6.965e-81	276.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DXAG@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2006697_11	1268072.PSAB_17415	1.044e-27	117.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26R8F@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_2006697_0	656024.FsymDg_3117	6.006e-135	452.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR21617310_k127_2006697_15	500153.JOEK01000014_gene5778	6.273e-10	71.0	COG2919@1|root,COG2919@2|Bacteria,2I3SE@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR21617310_k127_2006697_3	269800.Tfu_1102	2.455e-90	313.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4EH3F@85012|Streptosporangiales	201174|Actinobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR21617310_k127_2006697_10	1009370.ALO_20917	1.047e-42	162.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4H4A5@909932|Negativicutes	909932|Negativicutes	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR21617310_k127_2006697_5	471852.Tcur_0545	5.061e-73	267.0	COG1408@1|root,COG1408@2|Bacteria,2GM8M@201174|Actinobacteria,4ER1A@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR21617310_k127_2006697_9	1313172.YM304_19370	1.136e-47	186.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR21617310_k127_2006697_12	370438.PTH_2212	4.355e-27	120.0	COG2110@1|root,COG2755@1|root,COG2110@2|Bacteria,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,24N6X@186801|Clostridia,262J2@186807|Peptococcaceae	186801|Clostridia	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR21617310_k127_2006697_1	1206101.AZXC01000002_gene5977	9.481e-134	433.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR21617310_k127_2006697_4	33876.JNXY01000044_gene1908	3.227e-77	284.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DB81@85008|Micromonosporales	201174|Actinobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR21617310_k127_2006697_6	1120936.KB907210_gene5716	1.43e-66	254.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4EGNK@85012|Streptosporangiales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR21617310_k127_2006697_13	469371.Tbis_1394	1.431e-15	83.0	2E49S@1|root,32RRE@2|Bacteria,2I83P@201174|Actinobacteria,4EEC0@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR21617310_k127_2006697_8	875328.JDM601_1016	3.304e-54	200.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,23616@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_2006697_2	471852.Tcur_2940	3.588e-122	406.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4EH2D@85012|Streptosporangiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR21617310_k127_2006697_7	1048339.KB913029_gene3745	2.204e-57	209.0	COG0739@1|root,COG0739@2|Bacteria,2IBVX@201174|Actinobacteria	201174|Actinobacteria	M	Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR21617310_k127_2006697_14	292459.STH787	2.799e-15	84.0	COG4447@1|root,COG4447@2|Bacteria,1VG3Z@1239|Firmicutes,24TQ1@186801|Clostridia	186801|Clostridia	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR21617310_k127_200984_1	937777.Deipe_0466	2.088e-35	141.0	COG3941@1|root,COG3941@2|Bacteria	2|Bacteria	O	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR21617310_k127_200984_2	2074.JNYD01000013_gene6899	1.032e-10	70.0	2BGK0@1|root,32AID@2|Bacteria,2GQ1A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
SRR21617310_k127_200984_0	1246448.ANAZ01000065_gene5058	3.666e-37	145.0	2FB4K@1|root,343AZ@2|Bacteria,2IN2Y@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2011897_0	1237500.ANBA01000018_gene3775	1.128e-65	234.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria	201174|Actinobacteria	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
SRR21617310_k127_2013877_0	298654.FraEuI1c_5809	1.35e-11	72.0	COG0582@1|root,COG0582@2|Bacteria,2I9QS@201174|Actinobacteria,4ETT7@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_2014862_2	1157637.KB892106_gene3770	7.299e-35	136.0	COG0741@1|root,COG3209@1|root,COG0741@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TGFb_propeptide,Tox-REase-5
SRR21617310_k127_2014862_1	547163.BN979_00288	1.836e-64	226.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,235UK@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR21617310_k127_2014862_0	1169152.AXVD01000014_gene1496	4.817e-78	272.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4G185@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_2014862_4	742727.HMPREF9447_04464	1.618e-24	113.0	COG2961@1|root,COG2961@2|Bacteria,4PJCP@976|Bacteroidetes,2FREI@200643|Bacteroidia,4AKUI@815|Bacteroidaceae	976|Bacteroidetes	S	COG COG2961 Protein involved in catabolism of external DNA	-	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
SRR21617310_k127_2014862_6	1380386.JIAW01000029_gene3693	0.000208	54.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria,234S6@1762|Mycobacteriaceae	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SRR21617310_k127_2014862_5	101510.RHA1_ro11281	9.035e-05	55.0	COG0583@1|root,COG1695@1|root,COG0583@2|Bacteria,COG1695@2|Bacteria,2GNFI@201174|Actinobacteria,4G5YI@85025|Nocardiaceae	201174|Actinobacteria	K	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,TniQ
SRR21617310_k127_2014862_3	1265505.ATUG01000001_gene4389	6.895e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria,2MM35@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2015236_4	1150864.MILUP08_30219	8.478e-35	148.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4DA0U@85008|Micromonosporales	201174|Actinobacteria	S	single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR21617310_k127_2015236_3	1214101.BN159_4528	9.816e-46	179.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria	201174|Actinobacteria	U	Membrane protein insertase, YidC Oxa1 family	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR21617310_k127_2015236_5	2074.JNYD01000004_gene4862	1.878e-24	112.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR21617310_k127_2015236_7	562970.Btus_3322	7.58e-18	87.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,278N4@186823|Alicyclobacillaceae	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR21617310_k127_2015236_8	1274.HX89_00655	1.378e-12	73.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,1ZX26@145357|Dermacoccaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR21617310_k127_2015236_0	351607.Acel_0001	5.173e-184	585.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4ES24@85013|Frankiales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR21617310_k127_2015236_2	1313172.YM304_00020	1.133e-80	283.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CN18@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase III beta subunit	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR21617310_k127_2015236_1	1210045.ALNP01000002_gene4101	2.551e-113	376.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR21617310_k127_2015236_6	1227261.HMPREF0043_00053	1.267e-22	100.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D59T@85005|Actinomycetales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR21617310_k127_2018842_0	469371.Tbis_1422	7.855e-228	719.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2I12T@201174|Actinobacteria,4DX7Y@85010|Pseudonocardiales	201174|Actinobacteria	L	UvrD/REP helicase N-terminal domain	pcrA	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
SRR21617310_k127_2018842_2	469383.Cwoe_5638	2.154e-61	222.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4CQFH@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein GntR HTH	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR21617310_k127_2018842_3	1449350.OCH239_03725	4.08e-29	134.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,4KNMY@93682|Roseivivax	28211|Alphaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR21617310_k127_2018842_1	2002.JOEQ01000002_gene4471	3.262e-151	499.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EG9Z@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR21617310_k127_2020061_1	671143.DAMO_0449	3.945e-66	232.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3367,DUF5122,HemolysinCabind,NPCBM
SRR21617310_k127_2020061_0	298655.KI912266_gene4753	2.823e-81	281.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2020061_6	298653.Franean1_4658	3.628e-14	81.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_2020061_4	106370.Francci3_0101	9.55e-20	98.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR21617310_k127_2020061_5	251221.35210711	1.24e-14	77.0	COG3039@1|root,COG3039@2|Bacteria,1G52R@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_2020061_3	1121924.ATWH01000007_gene2038	3.11e-23	105.0	COG3385@1|root,COG3385@2|Bacteria,2GKQB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
SRR21617310_k127_2020061_2	446462.Amir_1743	2.641e-23	103.0	COG3385@1|root,COG3385@2|Bacteria,2GKQB@201174|Actinobacteria,4E3EH@85010|Pseudonocardiales	201174|Actinobacteria	L	Insertion element 4 transposase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
SRR21617310_k127_2020564_11	1089549.AZUQ01000001_gene906	4.797e-09	58.0	COG0584@1|root,COG0584@2|Bacteria,2GMMS@201174|Actinobacteria,4EYHK@85014|Glycomycetales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR21617310_k127_2020564_3	561175.KB894104_gene1208	1.381e-59	217.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4EHN0@85012|Streptosporangiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR21617310_k127_2020564_1	298654.FraEuI1c_0808	6.594e-100	334.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_2020564_10	1449346.JQMO01000003_gene3302	3.743e-15	89.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,2M30K@2063|Kitasatospora	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR21617310_k127_2020564_5	485913.Krac_4886	8.549e-48	190.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	tetV	-	-	ko:K18215	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.3	-	-	MFS_1,MFS_3
SRR21617310_k127_2020564_8	188626.HMPREF0321_1600	1.281e-33	135.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,1ZW2C@145357|Dermacoccaceae	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR21617310_k127_2020564_7	42256.RradSPS_1311	2.06e-41	166.0	COG1228@1|root,COG1228@2|Bacteria,2HENV@201174|Actinobacteria,4CTU9@84995|Rubrobacteria	84995|Rubrobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_2020564_0	525904.Tter_1206	1.191e-103	368.0	COG0215@1|root,COG0215@2|Bacteria,2NQRZ@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (C) catalytic domain	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR21617310_k127_2020564_9	1122138.AQUZ01000001_gene1687	1.322e-25	108.0	2BZ6B@1|root,30N1Q@2|Bacteria,2I097@201174|Actinobacteria,4DWBN@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2020564_2	649831.L083_8183	1.138e-94	325.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DAX4@85008|Micromonosporales	201174|Actinobacteria	L	AP endonuclease family 2	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR21617310_k127_2020564_4	1449976.KALB_1439	3.391e-49	190.0	COG2931@1|root,COG2931@2|Bacteria,2I3VG@201174|Actinobacteria	201174|Actinobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF3455
SRR21617310_k127_2020564_6	479434.Sthe_0360	9.553e-45	163.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2020863_9	1429046.RR21198_1694	8.183e-06	49.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4G8ND@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_2020863_7	909943.HIMB100_00020180	3.306e-14	78.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,4BQ0Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657,ko:K07659	ko02020,ko02026,map02020,map02026	M00434,M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2020863_5	1380354.JIAN01000005_gene1896	2.48e-26	118.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR21617310_k127_2020863_1	357808.RoseRS_0412	3.399e-41	173.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,374TD@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_8
SRR21617310_k127_2020863_8	1394178.AWOO02000007_gene3111	7.44e-10	70.0	COG0189@1|root,COG0189@2|Bacteria,2GP64@201174|Actinobacteria	201174|Actinobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	APH,RimK
SRR21617310_k127_2020863_2	1394178.AWOO02000007_gene3110	1.243e-40	167.0	COG0246@1|root,COG0246@2|Bacteria	2|Bacteria	G	mannitol metabolic process	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	HAD_2,Mannitol_dh,Mannitol_dh_C
SRR21617310_k127_2020863_6	1394178.AWOO02000007_gene3111	2.294e-24	116.0	COG0189@1|root,COG0189@2|Bacteria,2GP64@201174|Actinobacteria	201174|Actinobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	APH,RimK
SRR21617310_k127_2020863_3	1348663.KCH_09590	4.175e-34	143.0	COG0189@1|root,COG0189@2|Bacteria,2HXBM@201174|Actinobacteria,2M4S9@2063|Kitasatospora	201174|Actinobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
SRR21617310_k127_2020863_4	1121472.AQWN01000006_gene1757	1.388e-30	127.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,2616J@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2020863_0	211165.AJLN01000033_gene2690	4.127e-92	315.0	COG0477@1|root,COG2814@2|Bacteria,1GCP6@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2027334_1	1054860.KB913030_gene6480	3.209e-65	230.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR21617310_k127_2027334_3	1380347.JNII01000007_gene708	1.094e-24	107.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4ET4W@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR21617310_k127_2027334_4	1121106.JQKB01000057_gene611	7.006e-08	64.0	COG2227@1|root,COG2227@2|Bacteria,1QZVU@1224|Proteobacteria,2TYFD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_2027334_2	211114.JOEF01000011_gene5223	1.161e-51	191.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DYCU@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_2027334_0	211114.JOEF01000011_gene5223	1.276e-83	301.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DYCU@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_2031133_4	1246995.AFR_22780	2.352e-22	100.0	COG4106@1|root,COG4106@2|Bacteria,2I34Y@201174|Actinobacteria,4DMI2@85008|Micromonosporales	201174|Actinobacteria	S	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_2031133_3	543632.JOJL01000044_gene4968	2.173e-26	117.0	COG2132@1|root,COG2132@2|Bacteria,2I8HQ@201174|Actinobacteria,4DFGD@85008|Micromonosporales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2031133_0	479432.Sros_1513	2.518e-239	754.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4EH2B@85012|Streptosporangiales	201174|Actinobacteria	P	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR21617310_k127_2031133_2	2002.JOEQ01000004_gene2899	1.512e-55	203.0	2FIZ9@1|root,34AQ2@2|Bacteria,2INWA@201174|Actinobacteria,4EPMK@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2031133_1	479432.Sros_1511	2.992e-93	318.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR21617310_k127_2031133_5	1957.JODX01000018_gene1755	2.181e-07	55.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2036829_9	1122962.AULH01000045_gene3920	4.676e-72	258.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3719Y@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR21617310_k127_2036829_20	656024.FsymDg_3098	2.522e-30	126.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_2036829_13	1054860.KB913030_gene5159	1.033e-62	229.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria	201174|Actinobacteria	Q	o-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR21617310_k127_2036829_14	485913.Krac_2388	1.732e-57	203.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2036829_8	1123321.KB905828_gene561	7.255e-80	279.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria	201174|Actinobacteria	Q	o-methyltransferase	-	-	2.1.1.302	ko:K21377	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
SRR21617310_k127_2036829_11	1449353.JQMQ01000004_gene5962	1.346e-64	242.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,2NI6X@228398|Streptacidiphilus	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K21256	ko01059,ko01130,map01059,map01130	M00833,M00834	R11414	RC01363	ko00000,ko00001,ko00002	-	-	-	Trp_halogenase
SRR21617310_k127_2036829_1	485913.Krac_2391	8.703e-196	618.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458,ko:K14667	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR21617310_k127_2036829_2	485913.Krac_2392	2.116e-172	550.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR21617310_k127_2036829_21	485913.Krac_2393	4.59e-24	112.0	COG0736@1|root,COG0736@2|Bacteria	2|Bacteria	I	holo-[acyl-carrier-protein] synthase activity	acpS	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	ACPS
SRR21617310_k127_2036829_15	67356.KL575625_gene927	3.987e-50	182.0	COG2867@1|root,COG2867@2|Bacteria,2IKEG@201174|Actinobacteria	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_2036829_23	1121877.JQKF01000021_gene2197	3.114e-09	61.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR21617310_k127_2036829_7	1123252.ATZF01000006_gene889	2.017e-98	333.0	COG1878@1|root,COG1878@2|Bacteria,1USBQ@1239|Firmicutes,4HGJW@91061|Bacilli,27BZ1@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR21617310_k127_2036829_3	306281.AJLK01000159_gene408	6.699e-139	453.0	COG0654@1|root,COG0654@2|Bacteria,1G27G@1117|Cyanobacteria,1JJ6Z@1189|Stigonemataceae	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR21617310_k127_2036829_5	1096546.WYO_2647	6.282e-107	362.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,1JTU0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR21617310_k127_2036829_0	1137271.AZUM01000002_gene2528	1.039e-228	727.0	COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria,4E2CE@85010|Pseudonocardiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K18537,ko:K21224	ko01059,ko01130,map01059,map01130	M00831	R11389	RC03430	ko00000,ko00001,ko00002	-	-	-	B12-binding,Radical_SAM
SRR21617310_k127_2036829_4	356851.JOAN01000001_gene3590	2.114e-119	394.0	COG0500@1|root,COG2226@2|Bacteria,2IEAN@201174|Actinobacteria,4DM18@85008|Micromonosporales	201174|Actinobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
SRR21617310_k127_2036829_19	1502851.FG93_05079	3.542e-36	151.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2TQS4@28211|Alphaproteobacteria,3JU3N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	yeiE	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR21617310_k127_2036829_10	40571.JOEA01000005_gene4301	5.599e-71	248.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DZ9D@85010|Pseudonocardiales	2|Bacteria	E	ABC-type polar amino acid transport system, ATPase component	tupC	-	3.6.3.55	ko:K02065,ko:K02068,ko:K02071,ko:K05773,ko:K06857	ko02010,map02010	M00186,M00210,M00211,M00238,M00669,M00670	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.24,3.A.1.27,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
SRR21617310_k127_2036829_6	40571.JOEA01000005_gene4302	3.36e-101	339.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	glnH	-	-	ko:K02030,ko:K10039	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR21617310_k127_2036829_12	40571.JOEA01000005_gene4303	1.878e-63	228.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	glnM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR21617310_k127_2036829_16	40571.JOEA01000005_gene4304	3.428e-49	186.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR21617310_k127_2036829_17	40571.JOEA01000005_gene4305	5.637e-44	164.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR21617310_k127_2050982_0	1150864.MILUP08_43218	1.438e-158	525.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2050982_9	263358.VAB18032_23375	5.154e-10	62.0	2AGY4@1|root,3176Q@2|Bacteria,2HBIZ@201174|Actinobacteria,4DKB1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2050982_3	1380356.JNIK01000001_gene2097	4.61e-89	308.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4EV9Z@85013|Frankiales	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR21617310_k127_2050982_5	471852.Tcur_0831	4.113e-62	232.0	COG0449@1|root,COG0449@2|Bacteria,2H53Q@201174|Actinobacteria	201174|Actinobacteria	M	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
SRR21617310_k127_2050982_1	1206730.BAGA01000183_gene3174	1.835e-130	428.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pip	-	3.4.11.5,3.5.1.101	ko:K01259,ko:K18457	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR21617310_k127_2050982_6	710421.Mycch_3561	1.403e-59	215.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,2375M@1762|Mycobacteriaceae	201174|Actinobacteria	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR21617310_k127_2050982_7	298655.KI912267_gene7984	6.476e-46	175.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	pknE_1	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR21617310_k127_2050982_4	656024.FsymDg_3182	1.679e-62	228.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4ESB5@85013|Frankiales	201174|Actinobacteria	P	Cytochrome c oxidase caa3-type, assembly factor CtaG-related	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR21617310_k127_2050982_8	675635.Psed_0449	1.4e-23	111.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4E3EB@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR21617310_k127_2050982_2	649831.L083_3115	1.665e-111	376.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DAH5@85008|Micromonosporales	201174|Actinobacteria	C	cytochrome P450	-	-	1.14.14.1	ko:K00493,ko:K21257	ko00071,ko00380,ko00627,ko01059,ko01120,ko01130,map00071,map00380,map00627,map01059,map01120,map01130	M00833,M00834	R03629,R04121,R05259,R11415	RC00046,RC00236,RC01311	ko00000,ko00001,ko00002,ko01000	-	-	-	p450
SRR21617310_k127_2052723_14	28444.JODQ01000007_gene5989	2.213e-07	62.0	2DKWW@1|root,30NAT@2|Bacteria,2GKYJ@201174|Actinobacteria,4EIZX@85012|Streptosporangiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR21617310_k127_2052723_3	1394178.AWOO02000043_gene5878	5.648e-161	540.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR21617310_k127_2052723_4	1123322.KB904735_gene1520	1.102e-100	340.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2052723_7	1179773.BN6_29660	8.615e-78	273.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,PspC
SRR21617310_k127_2052723_6	1179773.BN6_29670	8.714e-85	291.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4EAKG@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_2052723_2	298655.KI912266_gene5385	3.328e-162	527.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4ERCB@85013|Frankiales	201174|Actinobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR21617310_k127_2052723_9	1223542.GM1_012_00890	5.521e-44	180.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4GE59@85026|Gordoniaceae	201174|Actinobacteria	K	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR21617310_k127_2052723_1	479432.Sros_1787	1.377e-201	656.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4EFUU@85012|Streptosporangiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR21617310_k127_2052723_0	1968.JOEV01000002_gene6871	1.283e-231	724.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_2052723_5	1123024.AUII01000001_gene2939	1.429e-99	332.0	COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
SRR21617310_k127_2052723_10	1123024.AUII01000001_gene2938	1.459e-17	86.0	2CEK1@1|root,2ZU8V@2|Bacteria,2HCUF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2052723_8	479432.Sros_4707	1.078e-65	231.0	COG2186@1|root,COG2186@2|Bacteria,2ICI2@201174|Actinobacteria,4EJYN@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_2052723_11	1123267.JONN01000001_gene1618	2.851e-16	90.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria	1224|Proteobacteria	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR21617310_k127_2052723_13	1463934.JOCF01000038_gene2259	2.618e-09	69.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,5.4.99.5	ko:K00210,ko:K04092,ko:K04093,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2925	CM_2,PDH
SRR21617310_k127_2052723_12	471852.Tcur_3912	6.942e-13	78.0	COG3595@1|root,COG3595@2|Bacteria,2I1WD@201174|Actinobacteria,4EPZD@85012|Streptosporangiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR21617310_k127_2053245_2	1380390.JIAT01000012_gene3281	9.971e-05	50.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_2053245_1	1380390.JIAT01000004_gene5209	5.626e-35	150.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_2053245_0	1380390.JIAT01000009_gene669	1.691e-58	219.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_2056553_2	356851.JOAN01000018_gene5680	3.422e-201	633.0	COG0827@1|root,COG0827@2|Bacteria,2I3BZ@201174|Actinobacteria	201174|Actinobacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056553_0	1869.MB27_19030	0.0	1506.0	COG1483@1|root,COG1483@2|Bacteria,2GMTG@201174|Actinobacteria,4DH3C@85008|Micromonosporales	201174|Actinobacteria	S	ATPase (AAA superfamily	pglY	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056553_1	1246995.AFR_29585	1.344e-223	716.0	COG1524@1|root,COG1524@2|Bacteria,2GK2R@201174|Actinobacteria,4DGUB@85008|Micromonosporales	201174|Actinobacteria	S	PglZ domain	pglZ	-	-	-	-	-	-	-	-	-	-	-	PglZ
SRR21617310_k127_2056969_26	298655.KI912266_gene4753	4.511e-11	64.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2056969_17	1464048.JNZS01000020_gene2129	4.467e-43	165.0	COG1813@1|root,COG1813@2|Bacteria,2HWQX@201174|Actinobacteria,4DK0X@85008|Micromonosporales	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_13	561175.KB894095_gene2568	1.136e-53	197.0	2DMWY@1|root,32U6G@2|Bacteria,2ISFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_15	882086.SacxiDRAFT_1221	1.014e-46	172.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR21617310_k127_2056969_12	1463920.JOGB01000025_gene4083	7.736e-55	204.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR21617310_k127_2056969_6	110319.CF8_0970	1.054e-97	325.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4DNHN@85009|Propionibacteriales	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR21617310_k127_2056969_7	1229780.BN381_10199	4.677e-85	310.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_18	1313172.YM304_20400	4.724e-38	164.0	COG3463@1|root,COG3463@2|Bacteria	2|Bacteria	T	Predicted membrane protein (DUF2079)	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2079,HisKA_3
SRR21617310_k127_2056969_16	269799.Gmet_0242	1.73e-45	179.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_2056969_19	469371.Tbis_0709	1.988e-37	146.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4E042@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR21617310_k127_2056969_14	1313172.YM304_20400	7.702e-48	194.0	COG3463@1|root,COG3463@2|Bacteria	2|Bacteria	T	Predicted membrane protein (DUF2079)	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2079,HisKA_3
SRR21617310_k127_2056969_2	562970.Btus_2812	1.902e-115	383.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,2797I@186823|Alicyclobacillaceae	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR21617310_k127_2056969_31	1304876.AZVC01000001_gene1613	0.0004454	49.0	2EBSZ@1|root,335SP@2|Bacteria,2GUT0@201174|Actinobacteria,1WA5M@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR21617310_k127_2056969_23	1194165.CAJF01000007_gene606	1.601e-14	81.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4FPQX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_29	396014.BF93_01745	1.027e-07	61.0	2CXFQ@1|root,32T1V@2|Bacteria,2GQYH@201174|Actinobacteria,4FD2W@85020|Dermabacteraceae	201174|Actinobacteria	S	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR21617310_k127_2056969_27	1120947.ATUX01000009_gene93	2.807e-08	57.0	2EG89@1|root,33A03@2|Bacteria,2GX3U@201174|Actinobacteria,4D6PD@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_11	526225.Gobs_1211	4.342e-72	254.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4ESC6@85013|Frankiales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_2056969_10	935866.JAER01000023_gene2335	1.648e-75	266.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,4DNMD@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_2056969_1	298655.KI912266_gene105	1.301e-160	517.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERKI@85013|Frankiales	201174|Actinobacteria	U	type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR21617310_k127_2056969_8	1380356.JNIK01000016_gene3559	1.067e-82	300.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4ERDT@85013|Frankiales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR21617310_k127_2056969_24	1122622.ATWJ01000015_gene645	3.662e-14	82.0	COG1261@1|root,COG1261@2|Bacteria,2GR8T@201174|Actinobacteria,4FGD8@85021|Intrasporangiaceae	201174|Actinobacteria	NO	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
SRR21617310_k127_2056969_21	1283283.ATXA01000002_gene2666	6.712e-22	98.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,4ETBQ@85013|Frankiales	201174|Actinobacteria	K	excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_2056969_25	1184607.AUCHE_08_06050	3.187e-12	75.0	2E4C6@1|root,32Z7Q@2|Bacteria,2HZBW@201174|Actinobacteria,4F7ZZ@85018|Dermatophilaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_28	367299.JOEE01000003_gene2934	7.287e-08	61.0	2DPN9@1|root,332RH@2|Bacteria,2IR7E@201174|Actinobacteria,4FGX4@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2056969_0	269800.Tfu_2490	0.0	1075.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR21617310_k127_2056969_5	58123.JOFJ01000004_gene1666	2.499e-99	335.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4EHYA@85012|Streptosporangiales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR21617310_k127_2056969_3	106370.Francci3_0765	3.534e-102	338.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4ERMX@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR21617310_k127_2056969_20	266117.Rxyl_1622	7.399e-34	137.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR21617310_k127_2056969_30	68223.JNZY01000026_gene7096	1.829e-06	59.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria	201174|Actinobacteria	S	phosphoribosyltransferase	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR21617310_k127_2056969_22	526225.Gobs_4283	1.325e-19	104.0	COG5401@1|root,COG5401@2|Bacteria,2GJ5Y@201174|Actinobacteria,4ESYV@85013|Frankiales	201174|Actinobacteria	S	Sporulation and spore germination	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR21617310_k127_2056969_9	1206101.AZXC01000023_gene3001	2.421e-81	291.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_2056969_4	570268.ANBB01000035_gene2239	1.464e-101	337.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4EFYW@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2078423_7	682795.AciX8_2290	2.83e-05	56.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL,TIG
SRR21617310_k127_2078423_5	216594.MMAR_1466	8.283e-14	72.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,238B5@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_2078423_0	1246995.AFR_17080	9.83e-213	672.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR21617310_k127_2078423_1	1906.SFRA_03310	2.404e-131	431.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4873
SRR21617310_k127_2078423_4	390235.PputW619_2329	1.838e-17	85.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,1S8SG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	multidrug resistance protein	emrE	GO:0003674,GO:0005215,GO:0005326,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006805,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006855,GO:0006950,GO:0006970,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009410,GO:0009628,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015199,GO:0015220,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015651,GO:0015672,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0015871,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031460,GO:0033554,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071466,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0072488,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR21617310_k127_2078423_6	587753.EY04_02415	8.607e-09	63.0	COG2076@1|root,COG2076@2|Bacteria,1N15X@1224|Proteobacteria	1224|Proteobacteria	P	membrane transporters of cations and cationic drugs	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR21617310_k127_2078423_2	1469245.JFBG01000010_gene595	5.001e-56	209.0	COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	homocysteine	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
SRR21617310_k127_2078423_3	290397.Adeh_0659	9.374e-24	110.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR21617310_k127_2088484_1	348824.LPU83_2024	2.264e-12	79.0	COG0741@1|root,COG3266@1|root,COG0741@2|Bacteria,COG3266@2|Bacteria,1QZ8S@1224|Proteobacteria,2URTR@28211|Alphaproteobacteria,4BG0Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2088484_0	43759.JNWK01000068_gene4168	1.885e-34	143.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1
SRR21617310_k127_2092719_18	1214101.BN159_5241	2.275e-11	64.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_2092719_21	1169161.KB897731_gene294	0.0005938	46.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_2092719_14	471852.Tcur_0336	4.809e-33	132.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4EFKV@85012|Streptosporangiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_2092719_16	1068980.ARVW01000001_gene1326	2.582e-23	105.0	COG2329@1|root,COG2329@2|Bacteria,2GZ5H@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_2092719_1	351607.Acel_2104	1.019e-146	476.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4EREN@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR21617310_k127_2092719_17	351607.Acel_2106	1.724e-22	103.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4ET89@85013|Frankiales	201174|Actinobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR21617310_k127_2092719_9	1125863.JAFN01000001_gene1413	1.885e-71	253.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR21617310_k127_2092719_5	1380347.JNII01000012_gene2697	2.975e-100	345.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4EU8D@85013|Frankiales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR21617310_k127_2092719_19	1449976.KALB_8042	7.394e-10	63.0	2E5D5@1|root,33055@2|Bacteria,2IR7Y@201174|Actinobacteria,4E6T9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2092719_4	1415166.NONO_c38250	6.222e-105	354.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FW27@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_2092719_7	477641.MODMU_4202	2.854e-75	267.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4EVFM@85013|Frankiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_2092719_12	269800.Tfu_3060	2.774e-42	165.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4EFW3@85012|Streptosporangiales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR21617310_k127_2092719_15	469371.Tbis_0050	1.515e-25	113.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4E2PP@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR21617310_k127_2092719_10	351607.Acel_0022	7.818e-66	244.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4ERJW@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	pstP	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR21617310_k127_2092719_2	935866.JAER01000017_gene4377	3.431e-120	414.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DPN4@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR21617310_k127_2092719_3	590998.Celf_0031	2.651e-115	406.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4F0UK@85016|Cellulomonadaceae	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR21617310_k127_2092719_8	1172188.KB911832_gene3944	1.614e-73	271.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FIBI@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_2092719_6	1089548.KI783301_gene1203	2.759e-80	285.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3WEHU@539002|Bacillales incertae sedis	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_2092719_11	673862.BABL1_334	2.014e-58	214.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR21617310_k127_2092719_13	1463861.JNXE01000002_gene6329	1.07e-40	165.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_2092719_0	469371.Tbis_2821	6.126e-238	753.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DYSM@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_2092719_20	656024.FsymDg_3761	0.0002882	52.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4ESEU@85013|Frankiales	201174|Actinobacteria	E	Acetolactate synthase, small subunit	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR21617310_k127_2093547_4	134676.ACPL_6189	1.285e-36	145.0	COG1670@1|root,COG1670@2|Bacteria,2IIEK@201174|Actinobacteria,4DG85@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_2093547_9	1123229.AUBC01000017_gene3892	2.586e-11	66.0	COG3246@1|root,COG3246@2|Bacteria,1NZS9@1224|Proteobacteria,2U35R@28211|Alphaproteobacteria,3JZMF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR21617310_k127_2093547_3	469383.Cwoe_4168	3.557e-89	301.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_2093547_7	469383.Cwoe_4202	1.15e-28	130.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2093547_6	1048339.KB913029_gene5071	1.358e-32	136.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4ERMX@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR21617310_k127_2093547_8	284031.JNXD01000017_gene6955	4.183e-28	124.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR21617310_k127_2093547_0	926560.KE387023_gene2049	1.542e-144	503.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR21617310_k127_2093547_2	345341.KUTG_08658	1.644e-92	314.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZDK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2093547_1	1449346.JQMO01000003_gene3280	6.106e-96	330.0	COG2211@1|root,COG2211@2|Bacteria,2I2X7@201174|Actinobacteria	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	MFS_1,MFS_3
SRR21617310_k127_2093547_5	1348663.KCH_23510	5.555e-34	138.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,2M3K1@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104180_5	1429046.RR21198_4923	1.301e-06	50.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR21617310_k127_2104180_0	710696.Intca_3585	1.123e-204	653.0	COG3055@1|root,COG3055@2|Bacteria,2I9Q1@201174|Actinobacteria	201174|Actinobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104180_2	1179773.BN6_31460	2.652e-141	469.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4DYUH@85010|Pseudonocardiales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_2104180_1	1120934.KB894415_gene3879	9.103e-144	466.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4E11C@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_2104180_4	1297742.A176_01335	1.751e-15	84.0	COG0863@1|root,COG0863@2|Bacteria,1P97D@1224|Proteobacteria,42S8M@68525|delta/epsilon subdivisions,2X85U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2104180_3	356851.JOAN01000002_gene845	2.464e-43	165.0	COG0537@1|root,COG0537@2|Bacteria,2IMBA@201174|Actinobacteria,4DEFU@85008|Micromonosporales	201174|Actinobacteria	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR21617310_k127_2104971_12	222534.KB893683_gene1182	2.383e-35	150.0	COG1807@1|root,COG1807@2|Bacteria,2H1H7@201174|Actinobacteria,4EW4Y@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104971_17	298654.FraEuI1c_6099	3.045e-07	59.0	COG1807@1|root,COG1807@2|Bacteria,2H1H7@201174|Actinobacteria,4EW4Y@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104971_3	1380393.JHVP01000004_gene680	4.961e-83	277.0	COG3631@1|root,COG3631@2|Bacteria,2II8E@201174|Actinobacteria,4EVCD@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_2104971_0	1463900.JOIX01000003_gene850	5.973e-299	936.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR21617310_k127_2104971_19	1380346.JNIH01000033_gene1224	0.0001301	52.0	COG2124@1|root,COG2124@2|Bacteria,2I2ZI@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104971_13	1206729.BAFZ01000041_gene4510	2.045e-34	141.0	COG0346@1|root,COG0346@2|Bacteria,2IQUP@201174|Actinobacteria,4G1DP@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2104971_2	266117.Rxyl_2806	3.284e-167	541.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,2GMFY@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
SRR21617310_k127_2104971_16	312284.A20C1_00275	6.206e-08	64.0	2B3QD@1|root,31WDY@2|Bacteria,2GX3A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2104971_10	1183438.GKIL_1251	6.195e-42	171.0	COG0726@1|root,COG0726@2|Bacteria,1G54X@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR21617310_k127_2104971_7	543632.JOJL01000005_gene4760	1.09e-74	267.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR21617310_k127_2104971_18	1455608.JDTH01000002_gene1046	0.0001159	53.0	COG3794@1|root,arCOG02920@2157|Archaea,2Y7VI@28890|Euryarchaeota,23VT8@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR21617310_k127_2104971_8	397278.JOJN01000002_gene412	7.316e-63	229.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4DNQY@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR21617310_k127_2104971_9	935839.JAGJ01000020_gene118	2.398e-46	181.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4F3B4@85017|Promicromonosporaceae	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR21617310_k127_2104971_6	477641.MODMU_0725	8.424e-77	262.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4ESNA@85013|Frankiales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR21617310_k127_2104971_1	1120936.KB907212_gene5320	1.562e-254	799.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4EGHW@85012|Streptosporangiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_2104971_4	525246.HMPREF0058_1304	1.017e-78	268.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4D3VU@85005|Actinomycetales	201174|Actinobacteria	F	GTP cyclohydrolase 1	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR21617310_k127_2104971_5	1123368.AUIS01000012_gene773	6.154e-77	271.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,2NBTN@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR21617310_k127_2104971_14	477974.Daud_0096	2.038e-24	115.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262W6@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR21617310_k127_2104971_11	1246445.ANAY01000011_gene845	3.39e-39	151.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4EJ6G@85012|Streptosporangiales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR21617310_k127_2104971_15	1120950.KB892707_gene4875	3.836e-20	97.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria,4DQJ6@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase domain	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR21617310_k127_2108956_1	323848.Nmul_A2452	7.588e-68	239.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,37367@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR21617310_k127_2108956_2	926560.KE387027_gene705	4.766e-37	149.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
SRR21617310_k127_2108956_4	1035308.AQYY01000001_gene3553	4.804e-22	100.0	COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,24K21@186801|Clostridia,266XS@186807|Peptococcaceae	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_2108956_0	1123024.AUII01000021_gene79	0.0	1033.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR21617310_k127_2108956_3	765420.OSCT_1705	1.618e-33	135.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,375U7@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR21617310_k127_2110089_8	935948.KE386494_gene390	6.097e-06	56.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42F3X@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR21617310_k127_2110089_6	1169161.KB897727_gene915	3.009e-43	180.0	COG1670@1|root,COG1670@2|Bacteria,2I4GW@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR21617310_k127_2110089_3	909613.UO65_0211	8.472e-99	336.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,4DZXM@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_2110089_5	909613.UO65_0213	4.851e-45	177.0	COG2227@1|root,COG2227@2|Bacteria,2ID71@201174|Actinobacteria	2|Bacteria	H	PFAM Methyltransferase type 11	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR21617310_k127_2110089_4	994479.GL877878_gene979	1.653e-67	244.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4E1NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	naringenin-chalcone synthase	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR21617310_k127_2110089_2	298653.Franean1_1105	2.954e-99	330.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4ERX7@85013|Frankiales	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR21617310_k127_2110089_1	469371.Tbis_2855	3.488e-121	401.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2110089_0	1120950.KB892741_gene2686	5.034e-145	478.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4DPQP@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR21617310_k127_2110089_7	1206741.BAFX01000118_gene7377	2.37e-17	89.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4G037@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2112433_2	357808.RoseRS_1234	4.648e-31	132.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2112433_1	1121468.AUBR01000023_gene2754	2.412e-57	215.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,42GWZ@68295|Thermoanaerobacterales	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR21617310_k127_2112433_3	1306406.ASHX01000001_gene4371	8.016e-11	66.0	2DMAG@1|root,32C8H@2|Bacteria,2IKM5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR21617310_k127_2112433_0	66874.JOFS01000005_gene3953	1.368e-80	272.0	COG1309@1|root,COG1309@2|Bacteria,2IFKE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2115189_4	525909.Afer_1826	1.369e-69	246.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4CNF9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR21617310_k127_2115189_1	35754.JNYJ01000075_gene8654	9.005e-151	507.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DAJX@85008|Micromonosporales	201174|Actinobacteria	C	Cytochrome b	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_2115189_11	1035308.AQYY01000002_gene978	6.381e-06	59.0	2D9MJ@1|root,32TTI@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRR21617310_k127_2115189_0	1151061.CAJY01000036_gene1491	2.285e-196	627.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR21617310_k127_2115189_6	471852.Tcur_3078	1.563e-44	171.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4EIXS@85012|Streptosporangiales	201174|Actinobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR21617310_k127_2115189_7	1254432.SCE1572_16555	3.537e-39	162.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
SRR21617310_k127_2115189_5	604331.AUHY01000034_gene2437	2.63e-48	181.0	COG0740@1|root,COG0740@2|Bacteria,1WI6Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR21617310_k127_2115189_9	164757.Mjls_2112	1.897e-19	98.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,23A45@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2115189_2	106370.Francci3_2905	3.32e-96	334.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4EU63@85013|Frankiales	201174|Actinobacteria	C	aldo keto reductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2115189_8	404589.Anae109_1809	4.704e-31	139.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
SRR21617310_k127_2115189_10	1123256.KB907927_gene1619	7.994e-18	97.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XD55@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
SRR21617310_k127_2115189_3	1120950.KB892757_gene6480	2.642e-92	325.0	COG0586@1|root,COG0586@2|Bacteria,2ICDR@201174|Actinobacteria,4DWRK@85009|Propionibacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR21617310_k127_2125417_1	656024.FsymDg_1022	1.109e-66	246.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2125417_4	446466.Cfla_3339	2.882e-18	90.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4F0QU@85016|Cellulomonadaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2125417_5	710696.Intca_3006	3.704e-09	64.0	28ZFG@1|root,2ZM70@2|Bacteria,2HB49@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2125417_0	196162.Noca_2944	9.732e-97	329.0	COG1290@1|root,COG1290@2|Bacteria,2ICE4@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_2125417_3	1380354.JIAN01000005_gene2678	1.558e-20	98.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR21617310_k127_2125417_2	1449353.JQMQ01000005_gene418	1.441e-28	117.0	2CD9C@1|root,2ZWAS@2|Bacteria,2GYGD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2129270_1	1123248.KB893326_gene1444	1.944e-125	454.0	COG1749@1|root,COG2372@1|root,COG4625@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG4625@2|Bacteria,COG5184@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
SRR21617310_k127_2129270_4	1267534.KB906757_gene911	9.34e-51	209.0	COG3867@1|root,COG4257@1|root,COG3867@2|Bacteria,COG4257@2|Bacteria,3Y9AI@57723|Acidobacteria	57723|Acidobacteria	V	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
SRR21617310_k127_2129270_0	686340.Metal_2450	1.067e-169	595.0	COG0613@1|root,COG4409@1|root,COG0613@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,CarboxypepD_reg,Gram_pos_anchor,Sialidase,YSIRK_signal
SRR21617310_k127_2129270_3	443143.GM18_1006	1.362e-51	212.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2129270_2	251229.Chro_4813	3.567e-66	260.0	COG1749@1|root,COG1749@2|Bacteria,1GBDW@1117|Cyanobacteria	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
SRR21617310_k127_2133720_2	994479.GL877879_gene5392	4.658e-73	256.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4DZS2@85010|Pseudonocardiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR21617310_k127_2133720_1	298653.Franean1_2060	7.922e-94	326.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EREI@85013|Frankiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR21617310_k127_2133720_0	935866.JAER01000002_gene1899	1.126e-237	750.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4DN4X@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR21617310_k127_2137150_19	512565.AMIS_42480	8.92e-38	149.0	2E5WA@1|root,330KC@2|Bacteria,2GWSH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2137150_13	1415166.NONO_c22480	4.31e-78	297.0	COG0553@1|root,COG0553@2|Bacteria,2GM2V@201174|Actinobacteria,4FV1M@85025|Nocardiaceae	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,SNF2_N
SRR21617310_k127_2137150_16	1123229.AUBC01000006_gene989	5.856e-61	217.0	COG0177@1|root,COG0177@2|Bacteria,1N2HB@1224|Proteobacteria,2U8WA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2137150_18	1127134.NOCYR_3433	1.268e-46	176.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,4G16I@85025|Nocardiaceae	201174|Actinobacteria	O	organic hydroperoxide resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR21617310_k127_2137150_4	1179773.BN6_01910	2.114e-240	764.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4DXBK@85010|Pseudonocardiales	201174|Actinobacteria	I	TIGRFAM Acetoacetyl-CoA synthase	acsA1	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR21617310_k127_2137150_5	710111.FraQA3DRAFT_5035	4.359e-228	723.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4ES5M@85013|Frankiales	201174|Actinobacteria	L	type III restriction protein res subunit	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR21617310_k127_2137150_14	452652.KSE_44260	1.074e-62	243.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,2M08X@2063|Kitasatospora	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR21617310_k127_2137150_12	485913.Krac_5141	3.883e-80	280.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2137150_21	1206729.BAFZ01000076_gene1425	9.269e-08	62.0	COG3599@1|root,COG3599@2|Bacteria,2I3F4@201174|Actinobacteria,4G2T7@85025|Nocardiaceae	201174|Actinobacteria	D	TIGRFAM DivIVA domain	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR21617310_k127_2137150_2	42256.RradSPS_1839	1.988e-307	962.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2IBPW@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR21617310_k127_2137150_6	324602.Caur_3220	3.508e-152	490.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR21617310_k127_2137150_9	1449346.JQMO01000002_gene1021	3.017e-99	343.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,2M5M7@2063|Kitasatospora	201174|Actinobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SRR21617310_k127_2137150_15	298655.KI912266_gene5505	2.713e-61	230.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4ET11@85013|Frankiales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR21617310_k127_2137150_7	103733.JNYO01000022_gene6994	3.001e-145	482.0	COG0654@1|root,COG0654@2|Bacteria,2GKIN@201174|Actinobacteria,4DY4H@85010|Pseudonocardiales	201174|Actinobacteria	CH	2-polyprenyl-6-methoxyphenol	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR21617310_k127_2137150_17	258052.JNYV01000015_gene3086	1.21e-52	202.0	COG1637@1|root,COG1637@2|Bacteria,2ICA9@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
SRR21617310_k127_2137150_1	1068978.AMETH_2756	8.264e-317	992.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4E0S6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR21617310_k127_2137150_10	298654.FraEuI1c_0966	5.386e-94	325.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4ERHN@85013|Frankiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	treX	-	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR21617310_k127_2137150_3	710111.FraQA3DRAFT_5704	1.419e-252	794.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4ERHA@85013|Frankiales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR21617310_k127_2137150_0	471852.Tcur_3582	4.6e-322	1005.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4EFHB@85012|Streptosporangiales	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR21617310_k127_2137150_8	1206729.BAFZ01000058_gene3375	1.74e-138	454.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4FUDW@85025|Nocardiaceae	1206729.BAFZ01000058_gene3375|-	J	Belongs to the amidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2137150_20	391625.PPSIR1_38696	1.79e-18	99.0	COG3386@1|root,COG3386@2|Bacteria,1RE3R@1224|Proteobacteria	1224|Proteobacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2137150_11	696747.NIES39_A01020	1.419e-90	304.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR21617310_k127_2141572_4	477641.MODMU_4434	3.511e-98	338.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4ERQY@85013|Frankiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR21617310_k127_2141572_3	67275.JOAP01000028_gene215	4.292e-102	344.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR21617310_k127_2141572_0	383372.Rcas_0084	1.001e-148	498.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2141572_11	1144275.COCOR_00594	4.201e-40	171.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,430R6@68525|delta/epsilon subdivisions,2WVZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4
SRR21617310_k127_2141572_1	1122182.KB903833_gene5325	1.593e-148	492.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DA22@85008|Micromonosporales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR21617310_k127_2141572_15	411474.COPEUT_00362	1.017e-27	117.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR21617310_k127_2141572_16	644966.Tmar_0959	2.271e-13	77.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3WDJD@538999|Clostridiales incertae sedis	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR21617310_k127_2141572_13	471852.Tcur_3421	7.227e-37	147.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4EJ2M@85012|Streptosporangiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR21617310_k127_2141572_5	1125712.HMPREF1316_0250	4.443e-81	277.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CV1X@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR21617310_k127_2141572_7	28042.GU90_17700	6.097e-48	188.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR21617310_k127_2141572_9	298655.KI912267_gene6705	1.948e-44	177.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4ESKU@85013|Frankiales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR21617310_k127_2141572_12	1121015.N789_05770	4.816e-39	153.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1X32M@135614|Xanthomonadales	135614|Xanthomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR21617310_k127_2141572_10	405948.SACE_6046	3.359e-40	161.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4E3KG@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR21617310_k127_2141572_6	525909.Afer_1145	1.936e-56	216.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_2141572_14	477641.MODMU_4409	2.791e-33	132.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4ETCV@85013|Frankiales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR21617310_k127_2141572_2	546414.Deide_17930	2.295e-147	486.0	COG0606@1|root,COG0606@2|Bacteria,1WI18@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR21617310_k127_2141572_8	1397528.Q671_14055	1.718e-44	175.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XJB4@135619|Oceanospirillales	135619|Oceanospirillales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR21617310_k127_214164_4	710111.FraQA3DRAFT_2963	3.132e-59	217.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR21617310_k127_214164_5	1121877.JQKF01000010_gene702	1.216e-05	57.0	2CC95@1|root,31D2W@2|Bacteria,2HGQY@201174|Actinobacteria,4CNT8@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_214164_2	103733.JNYO01000027_gene2471	9.956e-122	400.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DXB2@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Cell envelope-related transcriptional attenuator	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_214164_0	1380390.JIAT01000009_gene522	1.856e-231	732.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR21617310_k127_214164_1	644966.Tmar_0951	1.486e-137	459.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR21617310_k127_214164_3	1120950.KB892731_gene3814	2.797e-109	370.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4DTR5@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR21617310_k127_214164_6	1120936.KB907208_gene711	1.774e-05	47.0	COG0546@1|root,COG0546@2|Bacteria,2IKNN@201174|Actinobacteria,4EIVE@85012|Streptosporangiales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR21617310_k127_2143378_1	345219.Bcoa_1889	1.885e-145	468.0	COG0388@1|root,COG0388@2|Bacteria,1TT8F@1239|Firmicutes,4HDU6@91061|Bacilli,1ZQJU@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	amiE	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR21617310_k127_2143378_2	479432.Sros_0421	7.285e-59	211.0	29DTM@1|root,300RH@2|Bacteria,2HYGI@201174|Actinobacteria	201174|Actinobacteria	S	transporter	amiS	-	-	ko:K22112	-	-	-	-	ko00000,ko02000	1.A.29.1.1,1.A.29.1.2,1.A.29.1.6	-	-	AmiS_UreI
SRR21617310_k127_2143378_0	1968.JOEV01000036_gene1273	2.966e-147	475.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	amiC	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR21617310_k127_2143378_4	1968.JOEV01000036_gene1272	9.561e-35	142.0	COG1846@1|root,COG1846@2|Bacteria,2GQK4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_2143378_3	1449346.JQMO01000003_gene2737	8.236e-57	205.0	COG0590@1|root,COG0590@2|Bacteria,2GSFS@201174|Actinobacteria	201174|Actinobacteria	FJ	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	dCMP_cyt_deam_1
SRR21617310_k127_2144266_4	471852.Tcur_3068	6.624e-67	234.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4EHYE@85012|Streptosporangiales	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR21617310_k127_2144266_8	1429916.X566_12880	2.99e-28	123.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,3JYX6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR21617310_k127_2144266_0	865861.AZSU01000002_gene2932	4.735e-119	398.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR21617310_k127_2144266_9	1184609.KILIM_052_00270	4.653e-27	113.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4F730@85018|Dermatophilaceae	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR21617310_k127_2144266_10	298655.KI912266_gene4965	6.38e-27	118.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,4ET80@85013|Frankiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR21617310_k127_2144266_2	351607.Acel_0966	4.268e-107	359.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4ES7M@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR21617310_k127_2144266_11	350054.Mflv_4480	6.42e-19	91.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,239F2@1762|Mycobacteriaceae	201174|Actinobacteria	T	response regulator	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR21617310_k127_2144266_1	1463825.JNXC01000030_gene370	1.194e-116	398.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4DY7Y@85010|Pseudonocardiales	201174|Actinobacteria	E	glycine betaine	opuBA	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR21617310_k127_2144266_5	1229780.BN381_300040	5.776e-57	206.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,3UXGB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR21617310_k127_2144266_6	1123320.KB889585_gene1790	1.799e-48	183.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR21617310_k127_2144266_7	1380390.JIAT01000010_gene4789	3.582e-44	180.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CPP5@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR21617310_k127_2144266_3	498761.HM1_1864	4.454e-81	282.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR21617310_k127_2148752_2	370438.PTH_0620	2.903e-45	174.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,24BWJ@186801|Clostridia,261EP@186807|Peptococcaceae	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR21617310_k127_2148752_1	1352941.M877_11255	8.092e-108	356.0	COG0500@1|root,COG2226@2|Bacteria,2HVPX@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR21617310_k127_2148752_0	1380393.JHVP01000008_gene4711	2.905e-204	646.0	COG2730@1|root,COG2730@2|Bacteria,2IJWB@201174|Actinobacteria	201174|Actinobacteria	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
SRR21617310_k127_2153653_1	247156.NFA_15200	8.166e-06	53.0	2CIEV@1|root,30ANG@2|Bacteria,2GVCG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR21617310_k127_2153653_0	448385.sce8948	2.754e-07	61.0	COG4479@1|root,COG4479@2|Bacteria,1PR77@1224|Proteobacteria,430IX@68525|delta/epsilon subdivisions,2WW2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YozE SAM-like fold	-	-	-	-	-	-	-	-	-	-	-	-	YozE_SAM_like
SRR21617310_k127_2153653_2	446470.Snas_6269	2.086e-05	53.0	COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2166653_1	1463900.JOIX01000006_gene754	1.762e-36	156.0	2EXUT@1|root,33R41@2|Bacteria,2I3GV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2166653_3	1089546.AQUI01000002_gene165	3.457e-15	90.0	COG5412@1|root,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,40AC1@622450|Actinopolysporales	201174|Actinobacteria	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2166653_0	935866.JAER01000006_gene3408	1.091e-46	191.0	COG1345@1|root,COG5283@1|root,COG1345@2|Bacteria,COG5283@2|Bacteria	2|Bacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	PhageMin_Tail,TMP_2,Tape_meas_lam_C
SRR21617310_k127_2166653_2	1380346.JNIH01000064_gene5196	4.181e-18	87.0	2CGV7@1|root,2ZMW8@2|Bacteria,2GZG0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2170567_4	656024.FsymDg_2709	7.75e-35	138.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR21617310_k127_2170567_1	1380393.JHVP01000004_gene615	2.585e-69	250.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4ESAF@85013|Frankiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR21617310_k127_2170567_6	1206744.BAGL01000013_gene6076	6.693e-16	90.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4FWS8@85025|Nocardiaceae	201174|Actinobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR21617310_k127_2170567_3	543632.JOJL01000001_gene7861	9.934e-49	201.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4D9MT@85008|Micromonosporales	201174|Actinobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR21617310_k127_2170567_5	100226.SCO7493	1.208e-21	109.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria	201174|Actinobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR21617310_k127_2170567_0	298655.KI912266_gene2628	0.0	1127.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4ERFZ@85013|Frankiales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR21617310_k127_2170567_2	1177594.MIC448_980005	5.198e-69	238.0	COG0057@1|root,COG0057@2|Bacteria,2IEPZ@201174|Actinobacteria	201174|Actinobacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
SRR21617310_k127_2182617_4	106370.Francci3_3446	1.586e-101	341.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4EXB4@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2182617_5	266940.Krad_1545	1.144e-86	298.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2182617_8	345341.KUTG_02609	1.227e-64	228.0	29KMP@1|root,307IZ@2|Bacteria,2IM59@201174|Actinobacteria,4EB98@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2182617_2	1463917.JODC01000007_gene7779	2.134e-113	377.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria	201174|Actinobacteria	S	Low temperature requirement	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR21617310_k127_2182617_7	35754.JNYJ01000043_gene4416	2.095e-67	236.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4DK0U@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2182617_0	1298880.AUEV01000011_gene2663	5.201e-167	531.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR21617310_k127_2182617_3	675635.Psed_2325	1.14e-109	365.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DYPQ@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006,ko:K16784	ko02010,map02010	M00245,M00246,M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25.1	-	-	ABC_tran
SRR21617310_k127_2182617_1	1303518.CCALI_01547	8.359e-133	448.0	COG0310@1|root,COG0619@1|root,COG0310@2|Bacteria,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,CbiQ,PDGLE
SRR21617310_k127_2182617_10	479433.Caci_1395	3.429e-21	98.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_2182617_11	1869.MB27_08860	3.057e-07	61.0	29V0V@1|root,30GDY@2|Bacteria,2ICUU@201174|Actinobacteria,4DDYB@85008|Micromonosporales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_2182617_9	1120983.KB894577_gene3579	9.672e-55	203.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2U6JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR21617310_k127_2182617_6	477641.MODMU_2396	2.055e-70	257.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.14,1.1.1.380	ko:K00008,ko:K08322	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896,R10848	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_2184303_2	351607.Acel_1299	1.037e-105	354.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4ERR1@85013|Frankiales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR21617310_k127_2184303_0	211114.JOEF01000010_gene3310	0.0	1335.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4E0DG@85010|Pseudonocardiales	201174|Actinobacteria	EF	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR21617310_k127_2184303_4	351607.Acel_1297	5.706e-78	295.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4ESI4@85013|Frankiales	201174|Actinobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR21617310_k127_2184303_3	1121430.JMLG01000006_gene1759	2.539e-86	310.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR21617310_k127_2184303_13	1108045.GORHZ_050_00250	3.292e-05	49.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4GC2I@85026|Gordoniaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR21617310_k127_2184303_11	1120950.KB892811_gene7253	1.432e-26	116.0	COG1895@1|root,COG1895@2|Bacteria,2I82C@201174|Actinobacteria	201174|Actinobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2184303_8	1120950.KB892752_gene6177	2.911e-48	179.0	COG0640@1|root,COG0640@2|Bacteria,2I4A4@201174|Actinobacteria,4DS2M@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_2184303_1	469383.Cwoe_0139	6.431e-116	386.0	COG3214@1|root,COG3214@2|Bacteria,2HPYW@201174|Actinobacteria,4CRE6@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_2184303_7	561175.KB894098_gene5481	6.973e-51	195.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,4EHE6@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR21617310_k127_2184303_6	373903.Hore_09430	3.245e-51	193.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,3WAMQ@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR21617310_k127_2184303_10	1121272.KB903249_gene2530	1.751e-32	130.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4DE0A@85008|Micromonosporales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2184303_5	390989.JOEG01000012_gene3249	2.406e-54	203.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4DA6T@85008|Micromonosporales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR21617310_k127_2184303_12	1120954.ATXE01000002_gene1013	3.606e-20	92.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4DRNP@85009|Propionibacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR21617310_k127_2184303_9	1122222.AXWR01000026_gene1658	8.956e-43	166.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR21617310_k127_2185435_3	1299327.I546_0751	6.448e-18	89.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_2185435_2	1122939.ATUD01000010_gene2902	6.56e-34	138.0	COG3193@1|root,COG3193@2|Bacteria,2IHWI@201174|Actinobacteria,4CQRJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR21617310_k127_2185435_0	292459.STH658	2.579e-123	402.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2185435_1	63737.Npun_R3591	1.354e-47	192.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,1G09B@1117|Cyanobacteria,1HMTJ@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR21617310_k127_2185435_4	1463887.KL589952_gene5020	8.735e-18	89.0	28V6M@1|root,2ZH9T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2189303_1	710111.FraQA3DRAFT_2975	9.981e-67	240.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_2189303_0	981369.JQMJ01000004_gene5486	4.202e-135	449.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,2NHKA@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2189303_10	479432.Sros_4871	4.606e-08	66.0	COG4319@1|root,COG4319@2|Bacteria,2H89Q@201174|Actinobacteria,4EJG5@85012|Streptosporangiales	201174|Actinobacteria	S	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom,SnoaL_4
SRR21617310_k127_2189303_2	1352941.M877_02960	3.181e-62	221.0	COG4319@1|root,COG4319@2|Bacteria,2H89Q@201174|Actinobacteria	201174|Actinobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom,SnoaL_4
SRR21617310_k127_2189303_6	1312959.KI914671_gene3414	9.768e-47	174.0	COG2128@1|root,COG2128@2|Bacteria,2IHW3@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR21617310_k127_2189303_11	2074.JNYD01000002_gene5547	5.493e-06	53.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR21617310_k127_2189303_5	83332.Rv1190	2.678e-50	190.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23610@1762|Mycobacteriaceae	201174|Actinobacteria	S	Haloalkane dehalogenase	dhmA2	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_2189303_9	1386089.N865_05720	1.135e-18	92.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4FH3B@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_2189303_3	1123322.KB904636_gene2764	9.515e-53	189.0	COG0346@1|root,COG0346@2|Bacteria,2IFBN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2189303_8	1123321.KB905816_gene2413	3.891e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_2189303_4	298655.KI912266_gene4753	1.588e-51	190.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2189303_7	298653.Franean1_0441	6.663e-34	134.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_219210_12	1463921.JODF01000008_gene5445	4.687e-16	80.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_219210_1	28042.GU90_16820	4.12e-231	737.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E2BB@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	cutL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_219210_14	1121946.AUAX01000007_gene3011	1.873e-09	65.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4DBFR@85008|Micromonosporales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	prsR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR21617310_k127_219210_16	760568.Desku_2486	0.0002432	50.0	COG1396@1|root,COG1396@2|Bacteria,1VNFG@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR21617310_k127_219210_15	1507.HMPREF0262_03397	2.662e-08	59.0	COG1396@1|root,COG1396@2|Bacteria,1UHW9@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR21617310_k127_219210_13	1121017.AUFG01000007_gene1246	4.185e-11	66.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FI4Q@85021|Intrasporangiaceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_219210_4	66874.JOFS01000005_gene3908	3.836e-72	250.0	COG0491@1|root,COG0491@2|Bacteria,2GJ6X@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_219210_7	35754.JNYJ01000050_gene7963	1.399e-58	224.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4DBHK@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_219210_2	1214101.BN159_8305	1.284e-198	626.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR21617310_k127_219210_11	548479.HMPREF0573_11529	5.813e-22	99.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4D61Z@85005|Actinomycetales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR21617310_k127_219210_10	222534.KB893750_gene4277	3.321e-30	126.0	COG3682@1|root,COG3682@2|Bacteria,2GRHV@201174|Actinobacteria,4ETDA@85013|Frankiales	201174|Actinobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR21617310_k127_219210_6	390989.JOEG01000002_gene4360	4.918e-64	232.0	COG0501@1|root,COG0501@2|Bacteria,2GM27@201174|Actinobacteria,4DC0S@85008|Micromonosporales	201174|Actinobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR21617310_k127_219210_3	219305.MCAG_03785	1.384e-194	619.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4DCEF@85008|Micromonosporales	201174|Actinobacteria	E	Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR21617310_k127_219210_0	471852.Tcur_2644	0.0	1316.0	COG0642@1|root,COG0745@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2GKQX@201174|Actinobacteria,4EGCW@85012|Streptosporangiales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR21617310_k127_219210_5	861299.J421_0068	6.531e-66	249.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR21617310_k127_219210_9	1048339.KB913029_gene1696	1.869e-31	136.0	COG2197@1|root,COG2197@2|Bacteria,2I5BG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
SRR21617310_k127_219210_8	351607.Acel_0971	1.143e-39	164.0	COG0791@1|root,COG4942@1|root,COG0791@2|Bacteria,COG4942@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_2195674_16	1907.SGLAU_02845	2.988e-15	78.0	COG1371@1|root,COG1371@2|Bacteria,2IS0V@201174|Actinobacteria	201174|Actinobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR21617310_k127_2195674_2	1123024.AUII01000014_gene4289	5.637e-207	653.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4E0T7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the RtcB family	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR21617310_k127_2195674_17	196162.Noca_0285	1.48e-14	86.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR21617310_k127_2195674_4	991905.SL003B_1085	8.323e-135	440.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,4BQ89@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR21617310_k127_2195674_21	658187.LDG_7544	2.059e-08	66.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,1SEXH@1236|Gammaproteobacteria,1JF3E@118969|Legionellales	118969|Legionellales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR21617310_k127_2195674_10	2002.JOEQ01000021_gene6802	7.836e-38	163.0	COG1394@1|root,COG1394@2|Bacteria,2INZB@201174|Actinobacteria	201174|Actinobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR21617310_k127_2195674_1	284031.JNXD01000003_gene3711	1.749e-207	661.0	COG1156@1|root,COG1156@2|Bacteria,2GKPJ@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR21617310_k127_2195674_0	1206730.BAGA01000077_gene1082	7.36e-225	719.0	COG1155@1|root,COG1155@2|Bacteria,2HESQ@201174|Actinobacteria,4G5PD@85025|Nocardiaceae	201174|Actinobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SRR21617310_k127_2195674_13	55952.BU52_25985	2.475e-25	121.0	COG1390@1|root,COG1390@2|Bacteria,2GT2F@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
SRR21617310_k127_2195674_19	1449976.KALB_4143	2.512e-10	63.0	COG1436@1|root,COG1436@2|Bacteria,2I80G@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2195674_12	1157637.KB892091_gene5399	5.662e-30	136.0	COG0636@1|root,COG0636@2|Bacteria,2IS0Q@201174|Actinobacteria	201174|Actinobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR21617310_k127_2195674_3	2002.JOEQ01000021_gene6808	2.55e-143	467.0	COG1269@1|root,COG1269@2|Bacteria,2I9VH@201174|Actinobacteria	201174|Actinobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SRR21617310_k127_2195674_6	1894.JOER01000044_gene6753	2.792e-84	289.0	29KBT@1|root,30793@2|Bacteria,2IE0E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_AC39
SRR21617310_k127_2195674_14	68170.KL590523_gene3383	7.046e-18	90.0	2EDP7@1|root,337IW@2|Bacteria,2GT7G@201174|Actinobacteria,4ECZY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2195674_5	1172179.AUKV01000002_gene571	4.792e-111	366.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_2195674_15	639030.JHVA01000001_gene3028	3.377e-17	94.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria,2JK5H@204432|Acidobacteriia	204432|Acidobacteriia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR21617310_k127_2195674_20	1133849.O3I_040545	3.381e-10	68.0	2EQSP@1|root,33ICH@2|Bacteria,2GWX9@201174|Actinobacteria,4G2K3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2195674_7	1163409.UUA_11238	2.811e-79	283.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X3IK@135614|Xanthomonadales	135614|Xanthomonadales	CQ	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrome_CBB3
SRR21617310_k127_2195674_11	525909.Afer_1452	1.304e-32	133.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria,4CNRF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR21617310_k127_2195674_9	351607.Acel_0502	5.542e-43	163.0	COG5615@1|root,COG5615@2|Bacteria,2IHAA@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2195674_8	1121946.AUAX01000001_gene2403	1.585e-77	268.0	2F399@1|root,33W3K@2|Bacteria,2IMEX@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR21617310_k127_2195674_18	1120950.KB892779_gene892	8.417e-14	78.0	COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,2I35N@201174|Actinobacteria	201174|Actinobacteria	M	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
SRR21617310_k127_2195674_24	1237500.ANBA01000006_gene2585	1.97e-05	50.0	COG3599@1|root,COG3599@2|Bacteria,2GTIB@201174|Actinobacteria,4EKY1@85012|Streptosporangiales	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR21617310_k127_2195674_22	1122611.KB903954_gene5584	2.415e-07	57.0	COG5659@1|root,COG5659@2|Bacteria,2I565@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_2199124_1	2002.JOEQ01000016_gene7309	1.488e-71	245.0	COG2353@1|root,COG2353@2|Bacteria,2IG0K@201174|Actinobacteria,4EPKI@85012|Streptosporangiales	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR21617310_k127_2199124_0	671143.DAMO_2372	1.609e-85	304.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR21617310_k127_2199124_2	1449976.KALB_2972	2.928e-17	86.0	COG0457@1|root,COG0457@2|Bacteria,2I7SV@201174|Actinobacteria,4EEAZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2199124_3	1380393.JHVP01000012_gene2780	4.75e-13	81.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4ESBD@85013|Frankiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR21617310_k127_2199124_4	101510.RHA1_ro11115	1.551e-05	48.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR21617310_k127_2203524_0	404589.Anae109_2925	0.0	1100.0	COG1404@1|root,COG3940@1|root,COG1404@2|Bacteria,COG3940@2|Bacteria,1RCVP@1224|Proteobacteria	1224|Proteobacteria	O	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR21617310_k127_2203524_1	404589.Anae109_1827	1.341e-164	564.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
SRR21617310_k127_2203524_2	404589.Anae109_1826	1.348e-126	424.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
SRR21617310_k127_2205965_2	298655.KI912266_gene1797	7.265e-23	103.0	COG1917@1|root,COG1917@2|Bacteria,2IQI4@201174|Actinobacteria,4ET66@85013|Frankiales	201174|Actinobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2205965_0	1120972.AUMH01000019_gene2327	1.334e-214	694.0	COG3256@1|root,COG3256@2|Bacteria,1TSW2@1239|Firmicutes,4HCFR@91061|Bacilli,279NB@186823|Alicyclobacillaceae	91061|Bacilli	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRR21617310_k127_2205965_1	269799.Gmet_1011	4.259e-28	116.0	COG2329@1|root,COG2329@2|Bacteria,1P7F5@1224|Proteobacteria,432G7@68525|delta/epsilon subdivisions,2WXUX@28221|Deltaproteobacteria,43VXE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_2205965_3	485913.Krac_4690	4.856e-09	58.0	COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2209770_8	590998.Celf_0158	1.671e-76	261.0	COG3299@1|root,COG3299@2|Bacteria,2GM5C@201174|Actinobacteria	201174|Actinobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR21617310_k127_2209770_10	981369.JQMJ01000001_gene6794	6.899e-57	205.0	COG4385@1|root,COG4385@2|Bacteria,2HG1T@201174|Actinobacteria,2NIG6@228398|Streptacidiphilus	201174|Actinobacteria	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
SRR21617310_k127_2209770_19	1121946.AUAX01000015_gene6080	9.678e-18	97.0	29YK1@1|root,30KFA@2|Bacteria,2HWQG@201174|Actinobacteria,4DJY5@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2209770_0	479431.Namu_1911	3.785e-157	529.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I348@201174|Actinobacteria,4EUJ7@85013|Frankiales	201174|Actinobacteria	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR21617310_k127_2209770_24	1123258.AQXZ01000018_gene825	2.231e-06	52.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I348@201174|Actinobacteria,4G5D8@85025|Nocardiaceae	201174|Actinobacteria	KT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR21617310_k127_2209770_9	357808.RoseRS_2276	1.032e-70	270.0	COG0116@1|root,COG0116@2|Bacteria,2GBRV@200795|Chloroflexi,376UC@32061|Chloroflexia	32061|Chloroflexia	L	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
SRR21617310_k127_2209770_15	656024.FsymDg_1204	3.022e-26	113.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4EWZY@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR21617310_k127_2209770_6	405948.SACE_1244	6.242e-93	310.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4E5A4@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_2209770_5	326424.FRAAL1886	8.131e-97	332.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4ERNW@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	entS_1	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_2209770_22	1122951.ATUE01000005_gene1763	2.78e-07	64.0	COG1011@1|root,COG1011@2|Bacteria,1MVF8@1224|Proteobacteria,1T28K@1236|Gammaproteobacteria,3NMDW@468|Moraxellaceae	1236|Gammaproteobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR21617310_k127_2209770_17	867845.KI911784_gene1281	4.145e-22	108.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR21617310_k127_2209770_4	656024.FsymDg_0431	1.962e-98	342.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352,Pkinase
SRR21617310_k127_2209770_3	258533.BN977_03846	5.1e-116	388.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,233MR@1762|Mycobacteriaceae	201174|Actinobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR21617310_k127_2209770_16	370438.PTH_2772	6.198e-23	112.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia,260YH@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR21617310_k127_2209770_12	1389489.O159_00190	1.855e-42	168.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4FKRG@85023|Microbacteriaceae	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR21617310_k127_2209770_2	67332.FM21_13525	2.817e-128	420.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR21617310_k127_2209770_14	298653.Franean1_5654	1.009e-30	126.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4ESP5@85013|Frankiales	201174|Actinobacteria	S	PFAM Mov34 MPN PAD-1 family	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR21617310_k127_2209770_13	390989.JOEG01000023_gene5829	3.744e-35	141.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4DE3Z@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR21617310_k127_2209770_1	351607.Acel_1687	2.311e-140	451.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4ERDA@85013|Frankiales	201174|Actinobacteria	E	Cysteine synthase	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
SRR21617310_k127_2209770_18	47716.JOFH01000035_gene4111	1.201e-20	98.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria	201174|Actinobacteria	K	Divergent AAA domain protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR21617310_k127_2209770_20	1229780.BN381_100192	5.33e-17	83.0	COG1192@1|root,COG1192@2|Bacteria,2IC9Q@201174|Actinobacteria	201174|Actinobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR21617310_k127_2209770_21	298655.KI912266_gene6084	8.264e-09	67.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR21617310_k127_2209770_7	298654.FraEuI1c_4032	2.123e-78	284.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4EVAJ@85013|Frankiales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_2209770_11	981369.JQMJ01000004_gene4409	1.06e-44	166.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,2NF8W@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_221279_3	40041.SZO_17770	0.0001367	48.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
SRR21617310_k127_221279_1	1463858.JOHR01000032_gene5524	1.388e-159	514.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_221279_4	405948.SACE_1126	0.000402	51.0	2DSTW@1|root,33HE1@2|Bacteria,2GQ5Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_221279_0	222534.KB893766_gene2938	6.063e-273	857.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2213149_7	1137269.AZWL01000001_gene5670	5.486e-15	76.0	COG1309@1|root,COG1309@2|Bacteria,2GJQ1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_2213149_6	543632.JOJL01000004_gene4321	2.312e-19	100.0	28WNI@1|root,2ZINA@2|Bacteria,2GWW8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2213149_4	1068980.ARVW01000001_gene8288	1.158e-103	351.0	COG2508@1|root,COG2508@2|Bacteria,2I8HD@201174|Actinobacteria,4E4XX@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR21617310_k127_2213149_1	477641.MODMU_2207	6.632e-207	669.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2213149_0	1146883.BLASA_4595	5.813e-218	691.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4ERKA@85013|Frankiales	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
SRR21617310_k127_2213149_3	477641.MODMU_4005	1.217e-112	379.0	COG2267@1|root,COG2267@2|Bacteria,2GUBM@201174|Actinobacteria,4ESVB@85013|Frankiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	phaB	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR21617310_k127_2213149_2	1380347.JNII01000007_gene338	8.897e-192	604.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_2213149_9	512565.AMIS_28780	1.715e-07	53.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR21617310_k127_2213149_5	1449976.KALB_2204	1.272e-60	217.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_2213149_8	33876.JNXY01000078_gene1	1.051e-13	76.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_221321_13	1247649.D560_1326	3.363e-06	50.0	COG0642@1|root,COG1840@1|root,COG1840@2|Bacteria,COG2205@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T5B5@506|Alcaligenaceae	28216|Betaproteobacteria	T	Bacterial extracellular solute-binding protein	qseC_1	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA,SBP_bac_11
SRR21617310_k127_221321_14	43354.JOIJ01000004_gene3642	0.0008562	43.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DY70@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR21617310_k127_221321_6	304371.MCP_0389	3.743e-66	242.0	arCOG11014@1|root,arCOG11014@2157|Archaea,2XZ0A@28890|Euryarchaeota	2157|Archaea	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_221321_11	656024.FsymDg_1659	4.202e-09	59.0	COG4467@1|root,COG4467@2|Bacteria,2IDK7@201174|Actinobacteria	201174|Actinobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_221321_10	693661.Arcve_1075	8.891e-20	93.0	arCOG03230@1|root,arCOG03230@2157|Archaea	2157|Archaea	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR21617310_k127_221321_3	1125973.JNLC01000013_gene3804	1.138e-84	282.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,3JV5M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
SRR21617310_k127_221321_1	67267.JNXT01000049_gene7101	1.035e-114	393.0	COG1222@1|root,COG1222@2|Bacteria,2IA0X@201174|Actinobacteria	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR21617310_k127_221321_0	1429046.RR21198_1694	6.696e-204	648.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4G8ND@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_221321_7	1396141.BATP01000060_gene4688	4.519e-54	199.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia,2IVHP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR21617310_k127_221321_9	397278.JOJN01000003_gene2125	5.035e-26	108.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DRJS@85009|Propionibacteriales	201174|Actinobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR21617310_k127_221321_4	1380390.JIAT01000009_gene2005	9.134e-75	263.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR21617310_k127_221321_2	298655.KI912266_gene5255	5.389e-108	362.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4EUA7@85013|Frankiales	201174|Actinobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR21617310_k127_221321_5	661478.OP10G_4395	2.877e-71	260.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798,ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,Peptidase_M41,TPR_19,TPR_20
SRR21617310_k127_221321_8	865861.AZSU01000005_gene772	2.361e-41	169.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia,36F5C@31979|Clostridiaceae	186801|Clostridia	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR21617310_k127_2213589_1	517418.Ctha_0151	8.931e-177	567.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR21617310_k127_2213589_7	266940.Krad_1659	2.133e-15	84.0	COG1582@1|root,COG1582@2|Bacteria,2GRTC@201174|Actinobacteria	201174|Actinobacteria	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
SRR21617310_k127_2213589_3	351607.Acel_2032	2.709e-84	289.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ESHR@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase, sigma 28 subunit	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_2213589_6	1274.HX89_13210	2.358e-19	99.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,1ZWXA@145357|Dermacoccaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	hrrA2	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_2213589_5	909613.UO65_4134	1.336e-22	100.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4E5FK@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR21617310_k127_2213589_2	298653.Franean1_0158	1.062e-86	292.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4ERSR@85013|Frankiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR21617310_k127_2213589_4	1828.JOKB01000008_gene394	4.793e-26	114.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4G30U@85025|Nocardiaceae	201174|Actinobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR21617310_k127_2213589_0	469371.Tbis_3339	1.684e-238	758.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR21617310_k127_2213589_8	1123320.KB889676_gene2909	2.997e-05	47.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	cvnD6	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR21617310_k127_2216033_2	66875.JODY01000017_gene595	1.029e-10	67.0	2ASY2@1|root,31IDK@2|Bacteria,2IPQ5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2216033_1	643562.Daes_1136	1.293e-25	111.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,43A4D@68525|delta/epsilon subdivisions,2X1W9@28221|Deltaproteobacteria,2M9SN@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR21617310_k127_2216033_0	1214101.BN159_3068	3.727e-76	265.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR21617310_k127_2218052_8	1123023.JIAI01000004_gene7826	1.705e-45	176.0	2B2YI@1|root,31VJH@2|Bacteria,2GVT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2218052_6	1123023.JIAI01000004_gene7827	7.667e-93	311.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria,4E328@85010|Pseudonocardiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR21617310_k127_2218052_0	1123023.JIAI01000004_gene7828	0.0	1474.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4DZEM@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR21617310_k127_2218052_5	1123023.JIAI01000004_gene7829	7.271e-95	329.0	COG3058@1|root,COG3058@2|Bacteria	2|Bacteria	O	ferric iron binding	fdhE	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
SRR21617310_k127_2218052_2	1123023.JIAI01000004_gene7830	3.791e-153	486.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4E0GZ@85010|Pseudonocardiales	201174|Actinobacteria	C	formate dehydrogenase, beta subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRR21617310_k127_2218052_3	1123023.JIAI01000004_gene7831	1.251e-128	418.0	COG3301@1|root,COG3301@2|Bacteria	2|Bacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR21617310_k127_2218052_4	1120950.KB892707_gene4732	2.491e-127	412.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4DNMB@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2900c	Molybdopterin,Molydop_binding
SRR21617310_k127_2218052_1	266117.Rxyl_0146	3.673e-213	682.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4CQ1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR21617310_k127_2218052_10	1410668.JNKC01000016_gene993	2.21e-06	49.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2218052_7	266117.Rxyl_0142	1.841e-49	182.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR21617310_k127_2218052_9	1144275.COCOR_03695	7.605e-42	170.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2220324_42	405948.SACE_3751	1.163e-13	79.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4E66I@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR21617310_k127_2220324_40	1214101.BN159_7988	3.315e-15	88.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR21617310_k127_2220324_12	1089553.Tph_c23930	7.586e-113	379.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR21617310_k127_2220324_19	420324.KI912020_gene7468	6.514e-84	287.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,1JRKB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter	MA20_16895	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR21617310_k127_2220324_36	710696.Intca_1100	4.209e-45	183.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4FHKY@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter (Permease)	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR21617310_k127_2220324_33	469371.Tbis_2229	2.999e-48	177.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria,4E4KI@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_2220324_10	349161.Dred_1504	2.769e-127	441.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,263RX@186807|Peptococcaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2220324_1	1382356.JQMP01000003_gene1476	2.272e-195	655.0	COG1529@1|root,COG1529@2|Bacteria,2GBUE@200795|Chloroflexi,27Z0K@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2220324_14	639283.Snov_1273	8.152e-102	361.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,3F1EW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR21617310_k127_2220324_20	309801.trd_A0566	1.57e-80	278.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_2220324_29	316055.RPE_1655	1.297e-53	208.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,3JRGQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	MA20_09390	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_2220324_26	644966.Tmar_1480	1.694e-58	224.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_2220324_15	639283.Snov_1273	1.098e-97	335.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,3F1EW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR21617310_k127_2220324_2	1122611.KB903986_gene4005	3.218e-189	628.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EFKM@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2220324_5	1122611.KB903986_gene4005	6.926e-167	573.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EFKM@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2220324_11	1120949.KB903350_gene8127	2.847e-127	422.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DGWD@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR21617310_k127_2220324_38	1089552.KI911559_gene1084	1.383e-40	160.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria,2JPDX@204441|Rhodospirillales	204441|Rhodospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR21617310_k127_2220324_31	1536772.R70723_31175	3.43e-53	197.0	COG0600@1|root,COG0600@2|Bacteria,1UPIJ@1239|Firmicutes,4HD92@91061|Bacilli,26RCH@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR21617310_k127_2220324_23	1122921.KB898195_gene959	4.474e-73	269.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HEW0@91061|Bacilli,26RDX@186822|Paenibacillaceae	91061|Bacilli	M	Myristoyl transferase	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR21617310_k127_2220324_18	649638.Trad_0922	7.485e-92	308.0	COG1116@1|root,COG1116@2|Bacteria,1WM71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR21617310_k127_2220324_24	477974.Daud_0651	2.625e-62	232.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,26000@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR21617310_k127_2220324_25	1123060.JONP01000018_gene176	1.11e-61	223.0	COG4221@1|root,COG4221@2|Bacteria,1R08K@1224|Proteobacteria,2TUV8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR21617310_k127_2220324_34	1278078.G419_21215	9.663e-47	185.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4FY30@85025|Nocardiaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR21617310_k127_2220324_21	1089553.Tph_c23930	2.81e-77	287.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR21617310_k127_2220324_39	1444309.JAQG01000019_gene540	1.683e-33	141.0	COG1414@1|root,COG1414@2|Bacteria,1TQH9@1239|Firmicutes,4HCMT@91061|Bacilli,26XEU@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR21617310_k127_2220324_27	1382304.JNIL01000001_gene2759	6.205e-58	212.0	COG1099@1|root,COG1099@2|Bacteria,1UXNI@1239|Firmicutes,4HGRF@91061|Bacilli	91061|Bacilli	S	with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2220324_43	102232.GLO73106DRAFT_00019140	0.0002263	49.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7,TPR_8
SRR21617310_k127_2220324_32	1121324.CLIT_2c03230	5.894e-52	194.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRR21617310_k127_2220324_16	1120948.KB903243_gene2684	1.199e-96	321.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E1D6@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2220324_22	929712.KI912613_gene1355	4.886e-74	269.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CRHZ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_2220324_30	1123023.JIAI01000004_gene7968	1.958e-53	192.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_2220324_28	309801.trd_0577	1.085e-53	207.0	COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_2220324_3	1122611.KB903986_gene4005	1.136e-180	594.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EFKM@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2220324_41	1370121.AUWS01000050_gene1473	3.686e-14	78.0	COG3427@1|root,COG3427@2|Bacteria,2IH3I@201174|Actinobacteria,238T6@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR21617310_k127_2220324_9	390989.JOEG01000027_gene2172	5.906e-149	482.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4D9UZ@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR21617310_k127_2220324_17	1097668.BYI23_C007360	6.388e-92	320.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,1K4J5@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR21617310_k127_2220324_4	543632.JOJL01000017_gene9895	2.922e-174	569.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4DCJY@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR21617310_k127_2220324_6	709986.Deima_0372	1.32e-163	526.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C
SRR21617310_k127_2220324_7	709986.Deima_0371	6.585e-162	527.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	msuD	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR21617310_k127_2220324_13	1120949.KB903310_gene809	2.569e-104	354.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D9SZ@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2220324_35	397278.JOJN01000003_gene1944	1.705e-45	176.0	2DKVQ@1|root,30HQN@2|Bacteria,2I3KU@201174|Actinobacteria,4DQE9@85009|Propionibacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR21617310_k127_2220324_8	105420.BBPO01000003_gene1148	1.027e-161	542.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,2NFAB@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_2220324_37	710111.FraQA3DRAFT_1182	7.735e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,2GJXV@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_2220324_0	1449353.JQMQ01000005_gene1798	3.31e-207	657.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,2NHKA@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2223752_0	264732.Moth_1594	6.31e-211	679.0	COG1222@1|root,COG1222@2|Bacteria,1TRKW@1239|Firmicutes,24AMX@186801|Clostridia,42FQJ@68295|Thermoanaerobacterales	186801|Clostridia	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
SRR21617310_k127_2223752_5	1121952.ATXT01000014_gene1556	2.508e-22	104.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4FP7R@85023|Microbacteriaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR21617310_k127_2223752_7	667632.KB890164_gene1994	9.11e-08	59.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2WESG@28216|Betaproteobacteria,1K748@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K06867,ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4,Ank_5
SRR21617310_k127_2223752_3	298655.KI912266_gene4753	1.069e-41	160.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2223752_4	365528.KB891230_gene1839	1.668e-34	142.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2223752_6	485913.Krac_6235	5.979e-17	84.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR21617310_k127_2223752_2	298655.KI912266_gene4753	8.652e-107	364.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2223752_1	1380354.JIAN01000008_gene3481	1.354e-126	411.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4F29I@85016|Cellulomonadaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2223752_8	1045009.AFXQ01000002_gene1605	0.0001425	47.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,1W9DK@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR21617310_k127_2231836_2	1179773.BN6_40520	1.877e-50	187.0	COG2207@1|root,COG2207@2|Bacteria,2IHD7@201174|Actinobacteria	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR21617310_k127_2231836_4	1287276.X752_01185	5.807e-43	167.0	COG1280@1|root,COG1280@2|Bacteria,1RFU5@1224|Proteobacteria,2U9A7@28211|Alphaproteobacteria,43PMV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR21617310_k127_2231836_3	1894.JOER01000018_gene4993	3.2e-49	188.0	2EYB3@1|root,33RJG@2|Bacteria,2HR9Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2231836_0	644283.Micau_3474	1.618e-51	185.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4DG1J@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR21617310_k127_2231836_1	1125971.ASJB01000031_gene1241	5.748e-51	194.0	COG3409@1|root,COG3409@2|Bacteria,2HUBB@201174|Actinobacteria,4E7IY@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2239382_0	1120950.KB892748_gene3199	9.863e-244	771.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPPX@85009|Propionibacteriales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR21617310_k127_2239382_3	202952.BBLI01000035_gene2411	4.308e-32	143.0	COG0739@1|root,COG0739@2|Bacteria,1RK0U@1224|Proteobacteria,1SYMP@1236|Gammaproteobacteria,3NKAS@468|Moraxellaceae	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR21617310_k127_2239382_1	561175.KB894096_gene505	2.319e-53	192.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4EHKT@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR21617310_k127_2239382_2	656024.FsymDg_2178	2.465e-48	178.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4ESIT@85013|Frankiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR21617310_k127_2239382_4	525904.Tter_0033	6.371e-32	128.0	COG0634@1|root,COG0634@2|Bacteria,2NPER@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR21617310_k127_224105_0	58344.JOEL01000115_gene5536	2.798e-147	472.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_224105_7	1122915.AUGY01000135_gene2098	2.925e-22	103.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes	1239|Firmicutes	L	Reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_224105_10	58344.JOEL01000115_gene5536	9.408e-06	54.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_224105_4	285535.JOEY01000062_gene9987	7.969e-57	203.0	COG1510@1|root,COG1510@2|Bacteria,2INZH@201174|Actinobacteria	201174|Actinobacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_224105_1	1464048.JNZS01000012_gene3500	4.363e-128	417.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8T6@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_224105_3	1352941.M877_23680	1.289e-93	321.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_224105_8	525909.Afer_2014	5.255e-20	89.0	COG2801@1|root,COG2801@2|Bacteria,2HGWK@201174|Actinobacteria,4CNX9@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_224105_2	500153.JOEK01000002_gene310	1.898e-104	354.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	ydbC_1	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR21617310_k127_224105_6	1120950.KB892740_gene2599	5.509e-23	100.0	2DKIV@1|root,32UF6@2|Bacteria,2IN8G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_224105_9	65497.JODV01000021_gene2085	1.557e-09	60.0	COG3173@1|root,COG3173@2|Bacteria,2HH8W@201174|Actinobacteria,4E34T@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
SRR21617310_k127_2241114_1	1123023.JIAI01000006_gene76	3.602e-69	237.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E9NR@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_2241114_0	1157634.KB912988_gene4609	8.284e-114	372.0	COG5474@1|root,COG5474@2|Bacteria	2|Bacteria	S	COGs COG5474 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4365
SRR21617310_k127_2241114_3	665577.JH993790_gene5910	5.354e-25	106.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2241114_2	298653.Franean1_3039	5.119e-67	233.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_2243144_10	73044.JNXP01000023_gene878	5.68e-15	87.0	COG0758@1|root,COG0758@2|Bacteria,2IFTH@201174|Actinobacteria	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR21617310_k127_2243144_12	1121377.KB906407_gene966	3.113e-14	79.0	COG4696@1|root,COG4696@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	XK27_03185	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Acetyltransf_3,Hydrolase_3,PRA-PH
SRR21617310_k127_2243144_6	469371.Tbis_1730	2.881e-61	226.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_2243144_13	391037.Sare_0041	1.834e-12	79.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria,4D91Z@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2243144_14	314230.DSM3645_28207	7.265e-08	61.0	COG3344@1|root,COG3344@2|Bacteria,2IZGP@203682|Planctomycetes	203682|Planctomycetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_2243144_7	1906.SFRA_32930	2.671e-42	161.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_2243144_8	345341.KUTG_09258	8.068e-29	124.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_2243144_3	405948.SACE_2315	5.462e-114	376.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E9M1@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_2243144_11	222534.KB893789_gene195	1.87e-14	83.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_2243144_2	1463885.KL578366_gene2803	1.784e-132	429.0	COG0708@1|root,COG0708@2|Bacteria,2I7M4@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR21617310_k127_2243144_9	1382356.JQMP01000001_gene1211	1.258e-27	120.0	COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi,27YBX@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcription regulator	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR21617310_k127_2243144_0	1229172.JQFA01000002_gene5043	2.81e-146	479.0	COG0174@1|root,COG0174@2|Bacteria,1G3HB@1117|Cyanobacteria,1HF5M@1150|Oscillatoriales	1117|Cyanobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR21617310_k127_2243144_1	1223543.GP2_028_00590	1.797e-142	463.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,DUF1116,Ligase_CoA
SRR21617310_k127_2243144_4	986075.CathTA2_0425	3.083e-103	353.0	COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli	91061|Bacilli	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR21617310_k127_2243144_5	1206725.BAFU01000029_gene3011	2.959e-94	324.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4G3PB@85025|Nocardiaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_224854_0	443255.SCLAV_1029	5.033e-244	762.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria	201174|Actinobacteria	S	Modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR21617310_k127_224854_4	1394178.AWOO02000077_gene2070	3.936e-175	581.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4EGPS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR21617310_k127_224854_26	485913.Krac_4170	7.698e-49	185.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_224854_16	644283.Micau_0479	1.468e-80	276.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4DC3H@85008|Micromonosporales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR21617310_k127_224854_21	309801.trd_A0795	3.834e-61	231.0	COG0531@1|root,COG0531@2|Bacteria,2G76Z@200795|Chloroflexi	200795|Chloroflexi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_224854_17	1382306.JNIM01000001_gene2073	4.148e-77	289.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_224854_27	330084.JNYZ01000005_gene1104	3.389e-48	186.0	COG1609@1|root,COG1609@2|Bacteria,2GKKK@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR21617310_k127_224854_25	266117.Rxyl_0771	2.54e-52	199.0	arCOG06048@1|root,31EJQ@2|Bacteria,2GPSC@201174|Actinobacteria,4CQDB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_224854_13	1089553.Tph_c17120	8.251e-89	306.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,42FRV@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
SRR21617310_k127_224854_24	1408439.JHXW01000004_gene1353	9.639e-57	219.0	COG0006@1|root,COG0006@2|Bacteria,379I8@32066|Fusobacteria	32066|Fusobacteria	E	Psort location Cytoplasmic, score	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR21617310_k127_224854_23	1121380.JNIW01000002_gene2332	6.358e-59	212.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR21617310_k127_224854_3	1150399.AQYK01000002_gene3279	9.644e-181	596.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria,4FKEN@85023|Microbacteriaceae	201174|Actinobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR21617310_k127_224854_6	1380347.JNII01000012_gene2641	8.547e-149	512.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_224854_18	67352.JODS01000028_gene2361	1.107e-76	267.0	COG0511@1|root,COG0511@2|Bacteria,2GMCA@201174|Actinobacteria	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR21617310_k127_224854_20	324602.Caur_2455	6.742e-69	245.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR21617310_k127_224854_2	1121926.AXWO01000016_gene4075	8.658e-182	588.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4EY3X@85014|Glycomycetales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_224854_28	926564.KI911691_gene1223	4.75e-41	158.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4F52U@85017|Promicromonosporaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_224854_22	309801.trd_1336	7.147e-60	226.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_224854_12	446462.Amir_0401	4.276e-90	325.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4E0T0@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17331	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR21617310_k127_224854_14	66875.JODY01000004_gene3321	5.804e-88	301.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR21617310_k127_224854_7	1463825.JNXC01000034_gene2669	2.408e-141	465.0	COG1653@1|root,COG1653@2|Bacteria,2GKM8@201174|Actinobacteria,4DYH5@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17329	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_224854_31	211114.JOEF01000023_gene5794	2.73e-07	58.0	COG0010@1|root,COG0010@2|Bacteria,2HG7A@201174|Actinobacteria,4EC0H@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR21617310_k127_224854_30	883069.HMPREF9238_00896	7.328e-17	95.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4D3Q7@85005|Actinomycetales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_224854_32	981369.JQMJ01000003_gene7927	0.0001259	48.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,2NHD1@228398|Streptacidiphilus	201174|Actinobacteria	O	Bacterial TniB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_224854_11	953739.SVEN_0453	1.71e-94	326.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR21617310_k127_224854_1	266117.Rxyl_1765	4.475e-183	586.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CP8C@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_224854_15	1001240.GY21_13940	2.236e-82	283.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4FN19@85023|Microbacteriaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR21617310_k127_224854_8	2002.JOEQ01000005_gene3681	1.052e-119	393.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4EGHI@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
SRR21617310_k127_224854_19	1464048.JNZS01000012_gene3304	2.54e-71	258.0	COG2834@1|root,COG2834@2|Bacteria,2GKA2@201174|Actinobacteria,4D8U8@85008|Micromonosporales	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,MucB_RseB
SRR21617310_k127_224854_9	479432.Sros_3423	6.738e-110	359.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4EGJ6@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_224854_10	479432.Sros_3422	1.1e-109	373.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4EFUW@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_224854_5	1007103.AFHW01000011_gene6016	7.379e-170	542.0	COG1075@1|root,COG1075@2|Bacteria,1TQI5@1239|Firmicutes,4IJJ1@91061|Bacilli,26RM6@186822|Paenibacillaceae	91061|Bacilli	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR21617310_k127_224854_29	1278073.MYSTI_00218	5.511e-23	99.0	COG1309@1|root,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,430U2@68525|delta/epsilon subdivisions,2WW4Q@28221|Deltaproteobacteria,2YWUX@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2258100_1	1156844.KB891831_gene4452	7.948e-54	193.0	COG0537@1|root,COG0537@2|Bacteria,2IHAU@201174|Actinobacteria	201174|Actinobacteria	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR21617310_k127_2258100_0	1157637.KB892110_gene4271	6e-71	244.0	COG2318@1|root,COG2318@2|Bacteria,2HTVA@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_2258100_2	469383.Cwoe_4905	2.165e-34	151.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR21617310_k127_2258662_0	760568.Desku_3528	4.522e-95	317.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia,263QH@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR21617310_k127_2258662_1	36809.MAB_1810	1.899e-22	107.0	2BRGC@1|root,32KF8@2|Bacteria,2HBDS@201174|Actinobacteria	201174|Actinobacteria	S	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2258662_2	497964.CfE428DRAFT_3066	1.025e-08	65.0	COG1216@1|root,COG1216@2|Bacteria,46VR2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_2260684_10	909613.UO65_4475	3.028e-15	82.0	COG3146@1|root,COG3146@2|Bacteria,2HWRP@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	Acetyltransf_6
SRR21617310_k127_2260684_3	1120950.KB892743_gene3116	1.475e-98	335.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DU6A@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_2260684_2	1394178.AWOO02000088_gene963	1.005e-107	356.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHS4@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_2260684_9	1382306.JNIM01000001_gene539	1.351e-15	83.0	2EIKM@1|root,33CBX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2260684_4	525904.Tter_0555	2.482e-97	330.0	COG1085@1|root,COG1085@2|Bacteria,2NQV8@2323|unclassified Bacteria	2|Bacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR21617310_k127_2260684_5	42256.RradSPS_2227	1.734e-94	327.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR21617310_k127_2260684_0	44060.JODL01000004_gene2671	0.0	1405.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR21617310_k127_2260684_6	1122611.KB903990_gene7226	3.962e-76	278.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR21617310_k127_2260684_7	35754.JNYJ01000060_gene2510	2.666e-68	246.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4DDF4@85008|Micromonosporales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR21617310_k127_2260684_1	479433.Caci_1353	2.173e-183	582.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR21617310_k127_2260684_8	196162.Noca_2635	3.076e-64	226.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4DQZM@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_2267583_0	106370.Francci3_2860	6.117e-115	394.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_2267583_2	106370.Francci3_0642	1.392e-26	122.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_2267583_1	298655.KI912266_gene1966	9.213e-32	138.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4ET44@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_2267583_3	1122939.ATUD01000008_gene2505	7.083e-17	87.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR21617310_k127_2270295_17	211114.JOEF01000002_gene4098	1.738e-37	148.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4E4CI@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Helix-turn-helix	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR21617310_k127_2270295_21	1123320.KB889669_gene3186	0.0004252	49.0	2ED1B@1|root,336YA@2|Bacteria,2GQRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2270295_1	414996.IL38_03885	5.284e-127	420.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,407GH@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferases group 1	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2270295_16	309801.trd_1042	8.799e-48	194.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XV7@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR21617310_k127_2270295_4	391037.Sare_0365	1.454e-99	338.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4DD56@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_2270295_5	479432.Sros_5509	1.117e-90	305.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4EJ84@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR21617310_k127_2270295_15	1313172.YM304_28250	5.469e-58	215.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_2270295_3	1386089.N865_06095	1.063e-106	361.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4FE9Q@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2270295_19	656024.FsymDg_4082	1.285e-26	118.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4ESU9@85013|Frankiales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR21617310_k127_2270295_0	208444.JNYY01000001_gene5720	2.753e-146	473.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria,4E72B@85010|Pseudonocardiales	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR21617310_k127_2270295_8	706587.Desti_0471	2.126e-82	284.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,2MQUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_2270295_20	1206725.BAFU01000020_gene3500	8.876e-08	63.0	COG3468@1|root,COG3468@2|Bacteria,2GZBD@201174|Actinobacteria,4G19E@85025|Nocardiaceae	201174|Actinobacteria	MU	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637
SRR21617310_k127_2270295_12	656024.FsymDg_4205	1.95e-78	284.0	COG1108@1|root,COG1108@2|Bacteria,2IGW9@201174|Actinobacteria,4EXA0@85013|Frankiales	201174|Actinobacteria	P	ABC 3 transport family	yfeD	-	-	ko:K02075,ko:K09819	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR21617310_k127_2270295_9	656024.FsymDg_4206	1.876e-81	280.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4ETAC@85013|Frankiales	201174|Actinobacteria	P	PFAM ABC-3 protein	yfeC	-	-	ko:K02075,ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR21617310_k127_2270295_6	35754.JNYJ01000025_gene8934	1.08e-88	309.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4DCYV@85008|Micromonosporales	201174|Actinobacteria	P	ABC transporter	yfeB	-	-	ko:K02074,ko:K09820,ko:K11710	ko02010,map02010	M00243,M00244,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR21617310_k127_2270295_2	656024.FsymDg_4208	4.455e-108	358.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4ET8X@85013|Frankiales	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	yfeA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR21617310_k127_2270295_13	760568.Desku_1179	2.347e-72	261.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR21617310_k127_2270295_7	298654.FraEuI1c_6323	4.545e-87	293.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4ERYJ@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2270295_18	1299327.I546_7106	7.769e-28	114.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,236W9@1762|Mycobacteriaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR21617310_k127_2270295_11	40571.JOEA01000011_gene2303	4.94e-79	272.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DY3N@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR21617310_k127_2270295_14	649747.HMPREF0083_00885	7.543e-64	241.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,26U7E@186822|Paenibacillaceae	91061|Bacilli	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR21617310_k127_2270295_10	639030.JHVA01000001_gene270	8.769e-81	279.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR21617310_k127_2275754_0	44060.JODL01000006_gene1356	0.0	1208.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR21617310_k127_2275754_1	351607.Acel_1818	2.401e-117	392.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4ERJN@85013|Frankiales	201174|Actinobacteria	P	CBS domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR21617310_k127_2275754_2	1463879.JOHP01000018_gene2483	1.917e-49	183.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR21617310_k127_2277334_10	243230.DR_0249	1.105e-07	55.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2277334_0	644283.Micau_4731	1.829e-150	509.0	COG2909@1|root,COG2909@2|Bacteria,2HEIB@201174|Actinobacteria,4DCQ5@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
SRR21617310_k127_2277334_4	1120949.KB903328_gene9117	2.182e-57	206.0	COG3247@1|root,COG3247@2|Bacteria,2GSMH@201174|Actinobacteria,4DFMZ@85008|Micromonosporales	201174|Actinobacteria	S	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR21617310_k127_2277334_7	653045.Strvi_4871	2.977e-23	107.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_2277334_1	1120972.AUMH01000030_gene964	1.116e-133	437.0	COG0654@1|root,COG0654@2|Bacteria,1TSDI@1239|Firmicutes,4HAQG@91061|Bacilli	91061|Bacilli	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR21617310_k127_2277334_2	298653.Franean1_1685	3.533e-106	355.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4EU5Y@85013|Frankiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR21617310_k127_2277334_3	1448389.BAVQ01000002_gene2863	8.87e-101	334.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR21617310_k127_2277334_8	176275.XP_008602159.1	6.54e-21	107.0	COG1434@1|root,2S28H@2759|Eukaryota,3A0W3@33154|Opisthokonta,3P2AH@4751|Fungi,3QUAC@4890|Ascomycota,211W2@147550|Sordariomycetes,3TGUS@5125|Hypocreales	4751|Fungi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR21617310_k127_2277334_6	365046.Rta_11170	4.765e-27	127.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4AH8Z@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR21617310_k127_2277334_5	1137268.AZXF01000005_gene3188	2.929e-33	143.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4EFST@85012|Streptosporangiales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR21617310_k127_2282857_1	756067.MicvaDRAFT_0613	1.281e-100	338.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1G4CE@1117|Cyanobacteria,1HHT8@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_2282857_0	1278073.MYSTI_06017	7.45e-108	376.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria,2YYFT@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_2282857_4	101510.RHA1_ro05765	6.24e-06	59.0	COG1073@1|root,COG1073@2|Bacteria,2GKKT@201174|Actinobacteria,4FZKY@85025|Nocardiaceae	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR21617310_k127_2282857_3	1218074.BAXZ01000014_gene2977	4.954e-07	61.0	COG1073@1|root,COG1073@2|Bacteria,1RA55@1224|Proteobacteria,2VXHH@28216|Betaproteobacteria,1K0DN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR21617310_k127_2282857_2	471852.Tcur_0971	1.285e-34	142.0	COG0477@1|root,COG2814@2|Bacteria,2GMCR@201174|Actinobacteria,4EK18@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2283271_7	591157.SSLG_01661	1.127e-18	94.0	COG4733@1|root,COG5479@1|root,COG4733@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,SpoIID,VCBS
SRR21617310_k127_2283271_5	298654.FraEuI1c_6707	3.889e-28	121.0	COG3583@1|root,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
SRR21617310_k127_2283271_3	675635.Psed_3626	5.126e-38	150.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4E5TC@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_2283271_2	996637.SGM_1399	3.351e-51	192.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_2283271_6	1032480.MLP_23970	2.253e-25	116.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4DQJ3@85009|Propionibacteriales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR21617310_k127_2283271_0	35754.JNYJ01000101_gene9937	3.077e-263	828.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR21617310_k127_2283271_4	941449.dsx2_0494	2.14e-30	125.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2MBZF@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR21617310_k127_2283271_1	298655.KI912266_gene768	1.919e-104	343.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4ETZ5@85013|Frankiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR21617310_k127_2293696_1	479432.Sros_4254	3.655e-25	111.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJNW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR21617310_k127_2293696_0	867845.KI911784_gene2148	5.336e-77	276.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_2293696_2	1206720.BAFQ01000130_gene3216	3.378e-08	64.0	293HX@1|root,2ZR01@2|Bacteria,2GWV6@201174|Actinobacteria,4G48A@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2293696_3	1206737.BAGF01000054_gene3360	7.611e-06	51.0	2CD81@1|root,2ZR5P@2|Bacteria,2GY24@201174|Actinobacteria,4G53Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2297176_9	882083.SacmaDRAFT_1939	6.736e-51	189.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EABZ@85010|Pseudonocardiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR21617310_k127_2297176_14	1121936.AUHI01000012_gene1207	2.874e-17	87.0	COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR21617310_k127_2297176_4	1521187.JPIM01000137_gene2066	1.457e-137	447.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_2297176_12	589924.Ferp_2460	3.101e-22	98.0	COG0425@1|root,arCOG02062@2157|Archaea,2XZUG@28890|Euryarchaeota,246G4@183980|Archaeoglobi	183980|Archaeoglobi	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR21617310_k127_2297176_15	526227.Mesil_0167	7.429e-16	86.0	COG2210@1|root,COG2210@2|Bacteria	2|Bacteria	P	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
SRR21617310_k127_2297176_0	1120950.KB892778_gene1040	6.992e-286	886.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4DPCS@85009|Propionibacteriales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR21617310_k127_2297176_1	1120950.KB892778_gene1039	1.718e-206	657.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4DP1F@85009|Propionibacteriales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
SRR21617310_k127_2297176_2	1068980.ARVW01000001_gene5429	3.338e-174	578.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DYPK@85010|Pseudonocardiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
SRR21617310_k127_2297176_7	479432.Sros_4452	3.447e-83	291.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4EJWQ@85012|Streptosporangiales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR21617310_k127_2297176_8	479432.Sros_4451	1.108e-66	238.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2297176_11	111781.Lepto7376_2992	7.888e-29	123.0	COG1309@1|root,COG1309@2|Bacteria,1G51N@1117|Cyanobacteria,1HB9N@1150|Oscillatoriales	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR21617310_k127_2297176_5	909613.UO65_3308	2.006e-87	299.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria,4DZBX@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2297176_13	106370.Francci3_2703	6.414e-18	87.0	2E6IT@1|root,3315W@2|Bacteria,2GWJK@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR21617310_k127_2297176_10	1254432.SCE1572_31295	3.04e-31	126.0	COG4319@1|root,COG4319@2|Bacteria,1NKFM@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_3
SRR21617310_k127_2297176_16	1500890.JQNL01000001_gene2273	0.0001028	45.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,1RNYX@1236|Gammaproteobacteria,1X5AE@135614|Xanthomonadales	135614|Xanthomonadales	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR21617310_k127_2297176_6	1306174.JODP01000009_gene6544	6.574e-86	291.0	COG0639@1|root,COG0639@2|Bacteria,2HFPY@201174|Actinobacteria	201174|Actinobacteria	T	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR21617310_k127_2297176_3	710696.Intca_0489	2.265e-148	479.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR21617310_k127_2305017_6	882083.SacmaDRAFT_4482	4.548e-16	83.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria,4E1PA@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR21617310_k127_2305017_8	68199.JNZO01000027_gene6162	0.0006317	43.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR21617310_k127_2305017_0	479432.Sros_4819	1.754e-284	890.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4ENBU@85012|Streptosporangiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_2305017_1	1394178.AWOO02000081_gene2192	1.973e-156	509.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4EQSY@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR21617310_k127_2305017_5	1122138.AQUZ01000019_gene8163	6.277e-96	332.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DQD4@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 2, HAAT family	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_2305017_4	1122138.AQUZ01000019_gene8164	8.815e-103	341.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPPJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_2305017_2	1122138.AQUZ01000019_gene8165	2.524e-123	420.0	COG4177@1|root,COG4177@2|Bacteria,2I8MK@201174|Actinobacteria,4DRJH@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_2305017_3	1382356.JQMP01000001_gene1145	6.066e-106	355.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi,27YIM@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_2305017_7	649831.L083_5964	6.322e-05	51.0	2BYWD@1|root,31VGQ@2|Bacteria,2HWUY@201174|Actinobacteria,4DKEZ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2305310_1	222534.KB893783_gene5290	7.659e-105	367.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4ERQ7@85013|Frankiales	201174|Actinobacteria	T	PFAM PhoH family protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR21617310_k127_2305310_0	66875.JODY01000037_gene872	1.037e-155	512.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
SRR21617310_k127_2305310_2	1304865.JAGF01000001_gene1369	2.479e-62	232.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR21617310_k127_2312857_1	383372.Rcas_2064	6.241e-110	364.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR21617310_k127_2312857_3	471852.Tcur_2041	4.761e-58	210.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4EQYY@85012|Streptosporangiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_2312857_0	266117.Rxyl_2541	1.293e-133	436.0	COG3588@1|root,COG3588@2|Bacteria,2GJ0D@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Fructose-bisphosphate aldolase, class-I	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR21617310_k127_2312857_5	290399.Arth_3661	1.554e-34	137.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR21617310_k127_2312857_6	415426.Hbut_1145	8.517e-17	87.0	COG0517@1|root,arCOG00606@2157|Archaea,2XR8I@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_2312857_7	350058.Mvan_1377	9.605e-12	76.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,236GW@1762|Mycobacteriaceae	201174|Actinobacteria	J	Ribosome-associated protein Y (PSrp-1)	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR21617310_k127_2312857_4	469371.Tbis_1649	2.916e-37	150.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria,4EF6A@85010|Pseudonocardiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_2312857_8	1385511.N783_13185	1.652e-08	56.0	COG0809@1|root,COG0809@2|Bacteria,1UZJW@1239|Firmicutes,4HCRE@91061|Bacilli,2YBC1@289201|Pontibacillus	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR21617310_k127_2313010_17	710685.MycrhN_2907	8.658e-08	59.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,23CB7@1762|Mycobacteriaceae	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR21617310_k127_2313010_7	710685.MycrhN_2906	1.061e-117	393.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,233M1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR21617310_k127_2313010_2	1449355.JQNR01000004_gene1107	5.436e-191	606.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria	201174|Actinobacteria	F	Adenylosuccinate lyase	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR21617310_k127_2313010_5	710687.KI912270_gene4823	1.342e-129	422.0	2DBFP@1|root,2Z8ZG@2|Bacteria,2IAVA@201174|Actinobacteria,23DCC@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2313010_13	287986.DV20_09410	3.658e-50	186.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4E2XT@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR21617310_k127_2313010_6	1033802.SSPSH_000964	3.752e-123	407.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,1T4EF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2313010_15	1038860.AXAP01000006_gene6697	1.142e-39	162.0	2BR7C@1|root,32K5M@2|Bacteria,1NSIF@1224|Proteobacteria,2UPSU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2313010_11	357808.RoseRS_1342	6.056e-66	244.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
SRR21617310_k127_2313010_14	871968.DESME_09200	2.948e-41	163.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR21617310_k127_2313010_16	1123314.AUIO01000002_gene2040	1.859e-39	164.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR21617310_k127_2313010_8	1089544.KB912942_gene3148	3.882e-75	280.0	COG2203@1|root,COG3835@1|root,COG2203@2|Bacteria,COG3835@2|Bacteria,2IBPC@201174|Actinobacteria,4EAYJ@85010|Pseudonocardiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_30
SRR21617310_k127_2313010_0	196162.Noca_4827	2.44e-220	696.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4DN01@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.5	ko:K22364	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_2313010_4	309801.trd_1493	1.36e-144	472.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi,27XJB@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR21617310_k127_2313010_3	1382356.JQMP01000003_gene1613	6.879e-168	532.0	COG0022@1|root,COG0022@2|Bacteria,2G84F@200795|Chloroflexi,27XW7@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_2313010_9	177437.HRM2_47640	4.007e-74	270.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2MIUA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_2313010_10	1089553.Tph_c19630	4.826e-70	253.0	COG0061@1|root,COG0061@2|Bacteria,1UZVM@1239|Firmicutes,24B3V@186801|Clostridia,42F35@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM ATP-NAD AcoX kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
SRR21617310_k127_2313010_12	1009370.ALO_20137	1.336e-53	204.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H2DW@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_2313010_1	1097668.BYI23_C004790	5.999e-200	634.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,1KFGH@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR21617310_k127_2316021_5	292459.STH1353	1.96e-51	195.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_2316021_3	479434.Sthe_1877	2.884e-75	261.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR21617310_k127_2316021_0	1280390.CBQR020000164_gene4346	1.297e-188	605.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	lcfA	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2316021_7	326424.FRAAL2033	9.763e-45	172.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4ESQZ@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR21617310_k127_2316021_8	309801.trd_A0739	1.608e-20	101.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR21617310_k127_2316021_9	1122611.KB903952_gene5830	3.923e-09	66.0	2E4NY@1|root,32ZHR@2|Bacteria,2HZN4@201174|Actinobacteria,4EKK3@85012|Streptosporangiales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR21617310_k127_2316021_10	2423.NA23_0206765	1.813e-07	63.0	COG2331@1|root,COG2331@2|Bacteria,2GDJM@200918|Thermotogae	200918|Thermotogae	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR21617310_k127_2316021_4	298655.KI912266_gene1268	6.386e-64	225.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR21617310_k127_2316021_6	1463887.KL590052_gene5200	2.525e-47	180.0	COG3550@1|root,COG3550@2|Bacteria,2GJ1X@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR21617310_k127_2316021_2	1394178.AWOO02000054_gene8006	1.525e-112	381.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4EPD8@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2316021_1	1246995.AFR_13920	3.203e-145	489.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DA3B@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
SRR21617310_k127_2317224_20	1440053.JOEI01000002_gene3704	3.214e-06	49.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_2317224_15	929712.KI912613_gene4228	6.075e-46	177.0	COG0500@1|root,COG2226@2|Bacteria,2HNEB@201174|Actinobacteria,4CP8F@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_2317224_10	222534.KB893671_gene3191	1.702e-68	244.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4ESZY@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR21617310_k127_2317224_4	298654.FraEuI1c_6083	1.084e-112	374.0	COG0463@1|root,COG0463@2|Bacteria,2I568@201174|Actinobacteria,4ESA2@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_2317224_6	656024.FsymDg_0458	6.23e-96	343.0	COG1287@1|root,COG1287@2|Bacteria,2HBRT@201174|Actinobacteria,4EXCN@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2317224_16	479434.Sthe_1787	2.486e-28	134.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR21617310_k127_2317224_18	1340493.JNIF01000003_gene4568	2.177e-24	115.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K04786,ko:K12240,ko:K13613,ko:K15677	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,Condensation,Glyoxalase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,NUDIX,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR21617310_k127_2317224_1	1123024.AUII01000009_gene1953	2.103e-177	566.0	COG0388@1|root,COG0388@2|Bacteria,2HW1E@201174|Actinobacteria,4EAGX@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR21617310_k127_2317224_11	357808.RoseRS_4521	2.253e-62	224.0	COG1834@1|root,COG1834@2|Bacteria,2G7QT@200795|Chloroflexi,377RX@32061|Chloroflexia	32061|Chloroflexia	E	PFAM amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRR21617310_k127_2317224_9	1120950.KB892759_gene6224	4.364e-82	289.0	COG1397@1|root,COG1397@2|Bacteria,2GMYG@201174|Actinobacteria,4DTNF@85009|Propionibacteriales	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
SRR21617310_k127_2317224_14	710111.FraQA3DRAFT_6472	2.846e-56	200.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4ESVF@85013|Frankiales	201174|Actinobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR21617310_k127_2317224_17	680198.SCAB_8581	2.655e-25	115.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR21617310_k127_2317224_13	298654.FraEuI1c_0831	4.517e-61	222.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4EVRP@85013|Frankiales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR21617310_k127_2317224_12	375286.mma_0137	8.399e-62	218.0	COG1225@1|root,COG1225@2|Bacteria,1MWJP@1224|Proteobacteria,2VQ0B@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Redoxin	bcpB	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR21617310_k127_2317224_0	219305.MCAG_04706	4.252e-186	589.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DC9X@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_2317224_7	1121472.AQWN01000010_gene507	1.305e-93	318.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR21617310_k127_2317224_8	1003195.SCAT_0398	2.414e-83	283.0	COG0640@1|root,COG0640@2|Bacteria,2GTPG@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_2317224_3	1166948.JPZL01000004_gene171	1.167e-124	406.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,1S2T1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_2317224_5	909613.UO65_1874	5.51e-111	372.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_2317224_2	479432.Sros_1267	4.388e-139	458.0	COG0026@1|root,COG0026@2|Bacteria,2I3IE@201174|Actinobacteria,4EK7B@85012|Streptosporangiales	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR21617310_k127_2317224_19	3067.XP_002952540.1	5.499e-20	98.0	COG0542@1|root,KOG1051@2759|Eukaryota,37RK8@33090|Viridiplantae,34GR4@3041|Chlorophyta	3041|Chlorophyta	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_2319679_1	335543.Sfum_3753	1.8e-63	232.0	COG0826@1|root,COG0826@2|Bacteria,1N4QJ@1224|Proteobacteria,42YJR@68525|delta/epsilon subdivisions,2WUQ1@28221|Deltaproteobacteria,2MR6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
SRR21617310_k127_2319679_3	1896.JOAU01000012_gene956	3.837e-27	118.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR21617310_k127_2319679_4	383372.Rcas_4347	3.748e-24	110.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR21617310_k127_2319679_0	1380390.JIAT01000009_gene1182	9.018e-80	269.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria,4CQUD@84995|Rubrobacteria	84995|Rubrobacteria	S	GPR1/FUN34/yaaH family	-	-	-	-	-	-	-	-	-	-	-	-	Grp1_Fun34_YaaH
SRR21617310_k127_2328394_0	635013.TherJR_1754	3.279e-185	597.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR21617310_k127_2328394_1	401526.TcarDRAFT_1563	1.462e-165	539.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR21617310_k127_2328873_0	710696.Intca_2218	4.306e-65	229.0	2E5FQ@1|root,3307E@2|Bacteria,2INDB@201174|Actinobacteria,4FJME@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2328873_2	882083.SacmaDRAFT_5452	6.93e-29	120.0	28KX4@1|root,2ZAD4@2|Bacteria,2I8V3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
SRR21617310_k127_2328873_6	1040983.AXAE01000037_gene2581	3.22e-09	68.0	COG4454@1|root,COG4454@2|Bacteria,1N1PE@1224|Proteobacteria,2UCWF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,SoxE
SRR21617310_k127_2328873_7	1173027.Mic7113_2906	1.726e-05	57.0	COG0212@1|root,COG0212@2|Bacteria,1G3JC@1117|Cyanobacteria,1H7N4@1150|Oscillatoriales	1117|Cyanobacteria	H	5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR21617310_k127_2328873_4	1463855.JOHV01000102_gene522	3.859e-15	80.0	COG2865@1|root,COG2865@2|Bacteria,2II99@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR21617310_k127_2328873_5	682795.AciX8_3093	9.256e-10	63.0	2EZMH@1|root,33SSN@2|Bacteria,3Y6QX@57723|Acidobacteria,2JM7A@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2329226_14	1157637.KB892106_gene3781	1.731e-73	255.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2329226_9	1121272.KB903256_gene5557	4.106e-96	339.0	COG3055@1|root,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4DFPE@85008|Micromonosporales	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
SRR21617310_k127_2329226_33	1380346.JNIH01000005_gene3203	0.0002234	53.0	2EGC7@1|root,33A40@2|Bacteria,2HEC9@201174|Actinobacteria	201174|Actinobacteria	S	Trp biosynthesis associated, transmembrane protein, oprn chp	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
SRR21617310_k127_2329226_6	909613.UO65_0448	1.548e-142	483.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DYDE@85010|Pseudonocardiales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR21617310_k127_2329226_22	446471.Xcel_1495	2.165e-40	154.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4F4MU@85017|Promicromonosporaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SRR21617310_k127_2329226_3	561175.KB894095_gene2402	2.284e-172	550.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4EGJU@85012|Streptosporangiales	201174|Actinobacteria	G	Family 4 glycosyl hydrolase	malH	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
SRR21617310_k127_2329226_8	471852.Tcur_3857	8.275e-112	372.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria,4EFND@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR21617310_k127_2329226_0	266117.Rxyl_2529	0.0	1896.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR21617310_k127_2329226_18	1118054.CAGW01000108_gene3625	2.714e-50	188.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HFRY@91061|Bacilli,277EV@186822|Paenibacillaceae	91061|Bacilli	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_2329226_20	1089546.AQUI01000001_gene88	8.566e-43	177.0	COG0457@1|root,COG0457@2|Bacteria,2I4DB@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2329226_32	1121927.GOHSU_14_00080	1.468e-06	55.0	COG0789@1|root,COG0789@2|Bacteria,2I3PS@201174|Actinobacteria,4GEU3@85026|Gordoniaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_2329226_11	40571.JOEA01000008_gene2775	3.53e-89	316.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4DZBH@85010|Pseudonocardiales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR21617310_k127_2329226_12	1869.MB27_09285	4.088e-79	287.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4D8GE@85008|Micromonosporales	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR21617310_k127_2329226_17	106370.Francci3_3024	9.224e-55	201.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4ES6K@85013|Frankiales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR21617310_k127_2329226_15	106370.Francci3_3025	2.184e-62	232.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4ESDH@85013|Frankiales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR21617310_k127_2329226_10	446470.Snas_3996	1.296e-95	334.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4EXSN@85014|Glycomycetales	201174|Actinobacteria	E	Aminotransferase class I and II	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_2329226_7	656024.FsymDg_2502	8.764e-123	408.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4ERSZ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
SRR21617310_k127_2329226_21	471852.Tcur_2898	3.731e-41	174.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4EK29@85012|Streptosporangiales	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR21617310_k127_2329226_26	706587.Desti_2438	7.751e-16	85.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_2329226_25	1469613.JT55_19050	1.223e-16	88.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_2329226_16	365528.KB891262_gene5084	1.508e-60	215.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4ESIB@85013|Frankiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR21617310_k127_2329226_4	653045.Strvi_5719	1.667e-170	545.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_2329226_5	452652.KSE_69620	2.887e-160	517.0	COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria,2M15H@2063|Kitasatospora	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR21617310_k127_2329226_2	446471.Xcel_1296	0.0	1120.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4F476@85017|Promicromonosporaceae	201174|Actinobacteria	L	DNA polymerase alpha chain like domain	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR21617310_k127_2329226_13	1123253.AUBD01000009_gene2246	8.092e-76	276.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1X3AV@135614|Xanthomonadales	135614|Xanthomonadales	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR21617310_k127_2329226_24	1394178.AWOO02000032_gene4863	7.924e-34	141.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4EJGE@85012|Streptosporangiales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR21617310_k127_2329226_27	383372.Rcas_0280	9.198e-16	85.0	COG1734@1|root,COG1734@2|Bacteria,2G7BM@200795|Chloroflexi,377WS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM zinc finger, DksA TraR C4-type	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR21617310_k127_2329226_1	1120936.KB907210_gene5693	0.0	1140.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4EHRZ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR21617310_k127_2329226_28	575540.Isop_1664	6.084e-15	84.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2329226_29	471852.Tcur_2919	3.458e-14	83.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4EHS9@85012|Streptosporangiales	201174|Actinobacteria	D	DivIVA protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR21617310_k127_2329226_31	106370.Francci3_1422	1.581e-10	64.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR21617310_k127_2329226_23	1283299.AUKG01000002_gene4919	1.009e-35	141.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR21617310_k127_2329226_19	1121439.dsat_2792	1.415e-48	186.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MB0W@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR21617310_k127_2329226_30	765910.MARPU_10365	4.11e-13	72.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1WX0I@135613|Chromatiales	135613|Chromatiales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR21617310_k127_2332429_2	58344.JOEL01000010_gene5807	3.583e-07	51.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_2332429_1	930171.Asphe3_41780	5.757e-09	63.0	2EMV9@1|root,33FHI@2|Bacteria,2GZNR@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2332429_0	222534.KB893766_gene2938	7.772e-231	724.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2338678_1	935866.JAER01000035_gene3240	5.355e-85	291.0	COG1948@1|root,COG1948@2|Bacteria,2HAMQ@201174|Actinobacteria,4DTJV@85009|Propionibacteriales	201174|Actinobacteria	L	ERCC4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ERCC4,Lsr2
SRR21617310_k127_2338678_0	1380370.JIBA01000017_gene2924	9.056e-205	656.0	COG3055@1|root,COG3055@2|Bacteria,2IA06@201174|Actinobacteria,4FIGW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2338678_2	298655.KI912266_gene795	1.617e-84	303.0	COG0723@1|root,COG0723@2|Bacteria,2I2RI@201174|Actinobacteria,4EUMX@85013|Frankiales	201174|Actinobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2338678_3	575540.Isop_0468	1.97e-44	181.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,2J55B@203682|Planctomycetes	203682|Planctomycetes	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_2338678_4	1155714.KB891997_gene601	6.184e-36	143.0	COG4346@1|root,COG4346@2|Bacteria,2HFBS@201174|Actinobacteria	201174|Actinobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SRR21617310_k127_2340409_5	374847.Kcr_0796	2.624e-07	57.0	COG2423@1|root,arCOG01035@2157|Archaea	2157|Archaea	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	ala	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR21617310_k127_2340409_4	1206744.BAGL01000068_gene5014	1.974e-07	63.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4G24K@85025|Nocardiaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR21617310_k127_2340409_6	266940.Krad_3039	4.19e-06	57.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR21617310_k127_2340409_2	110319.CF8_4068	6.514e-28	131.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria,4DS7R@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
SRR21617310_k127_2340409_0	471852.Tcur_1835	3.851e-98	329.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria,4EI0I@85012|Streptosporangiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR21617310_k127_2340409_3	298655.KI912266_gene4805	8.507e-15	76.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_2343716_0	1089553.Tph_c01350	2.583e-174	565.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,42FY1@68295|Thermoanaerobacterales	186801|Clostridia	L	Best Blastp hit gi 4323609 gb AAD16446.1 (AF101410) transposase Mycoplasma mycoides subsp. mycoides SC gi 4323611 gb AAD16447.1 (AF101411) transposase Mycoplasma mycoides subsp. mycoides SC gi 4323613 gb AAD16448.1 (AF101412) transposase Mycoplasma mycoides subsp. mycoides SC , score	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR21617310_k127_234376_6	1304865.JAGF01000001_gene1549	1.005e-25	113.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	phaD	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
SRR21617310_k127_234376_7	1519464.HY22_11935	8.634e-07	55.0	COG0469@1|root,COG0469@2|Bacteria	2|Bacteria	G	pyruvate kinase activity	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
SRR21617310_k127_234376_1	1463825.JNXC01000023_gene4894	1.866e-104	349.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_234376_0	479432.Sros_4198	2.06e-138	446.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EJ1J@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR21617310_k127_234376_2	298655.KI912266_gene4753	5.979e-66	233.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_234376_4	1463879.JOHP01000005_gene6013	5.072e-39	156.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_234376_5	1121952.ATXT01000014_gene1646	1.346e-31	131.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_234376_3	1169161.KB897716_gene6021	4.248e-39	148.0	COG1309@1|root,COG1309@2|Bacteria,2GJQ1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_2347399_3	357808.RoseRS_3419	2.042e-20	105.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_2347399_4	543632.JOJL01000029_gene3593	1.252e-13	79.0	COG0583@1|root,COG0583@2|Bacteria,2GNM9@201174|Actinobacteria,4D8JN@85008|Micromonosporales	201174|Actinobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR21617310_k127_2347399_1	1463920.JOGB01000006_gene198	7.912e-59	211.0	COG0583@1|root,COG0583@2|Bacteria,2GNM9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR21617310_k127_2347399_0	68194.JNXR01000006_gene3712	2.049e-67	240.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_2347399_2	243090.RB11303	4.155e-43	178.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_2351696_12	1122182.KB903825_gene383	7.076e-46	168.0	arCOG11412@1|root,31S84@2|Bacteria,2IHRW@201174|Actinobacteria,4DEKD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2351696_4	446462.Amir_5390	5.197e-82	274.0	2DVEK@1|root,33VIT@2|Bacteria,2IG5Q@201174|Actinobacteria,4E2J3@85010|Pseudonocardiales	201174|Actinobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR21617310_k127_2351696_0	479431.Namu_1899	2.025e-246	774.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria,4ES03@85013|Frankiales	201174|Actinobacteria	S	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR21617310_k127_2351696_11	446462.Amir_5392	7.015e-51	193.0	COG2885@1|root,COG2885@2|Bacteria,2I4PT@201174|Actinobacteria,4E0BD@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR21617310_k127_2351696_2	543632.JOJL01000042_gene4456	1.277e-114	393.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	BsuPI,LysM,PG_binding_1,Peptidase_M15_4
SRR21617310_k127_2351696_1	1122182.KB903825_gene792	1.896e-195	635.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria,4DBTN@85008|Micromonosporales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR21617310_k127_2351696_5	479431.Namu_1892	1.551e-80	275.0	28RC2@1|root,2ZDRH@2|Bacteria,2GNI9@201174|Actinobacteria,4EVEW@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR21617310_k127_2351696_7	479431.Namu_1891	2.603e-74	256.0	COG2197@1|root,COG2197@2|Bacteria,2GNUE@201174|Actinobacteria,4EVX9@85013|Frankiales	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR21617310_k127_2351696_8	1122182.KB903825_gene796	5.517e-69	258.0	COG1470@1|root,COG1470@2|Bacteria,2H4ZH@201174|Actinobacteria,4DDR7@85008|Micromonosporales	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR21617310_k127_2351696_17	298655.KI912266_gene180	8.413e-33	146.0	COG1807@1|root,COG1807@2|Bacteria,2H1H7@201174|Actinobacteria,4EW4Y@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2351696_9	953739.SVEN_0549	1.307e-65	229.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_2351696_13	525904.Tter_0358	2.223e-45	179.0	COG3266@1|root,COG4719@1|root,COG3266@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF11,Pkinase
SRR21617310_k127_2351696_16	397278.JOJN01000004_gene1218	4.646e-35	147.0	2C6J1@1|root,33H0F@2|Bacteria,2IMXS@201174|Actinobacteria,4DUB6@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2351696_14	1131269.AQVV01000059_gene2298	1.312e-41	164.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_2351696_18	66373.JOFQ01000001_gene1893	5.459e-31	128.0	COG3427@1|root,COG3427@2|Bacteria,2I3CZ@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2351696_15	859657.RPSI07_mp0887	1.728e-41	156.0	COG1917@1|root,COG1917@2|Bacteria,1NFZN@1224|Proteobacteria,2W2T8@28216|Betaproteobacteria,1KDHR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
SRR21617310_k127_2351696_3	1121946.AUAX01000001_gene2357	3.28e-105	347.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4D9Y4@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_2351696_10	512565.AMIS_29310	1.197e-56	200.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4D9Y4@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_2351696_6	1382306.JNIM01000001_gene3724	2.966e-78	285.0	28MZV@1|root,2ZB6H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2355553_14	1463879.JOHP01000047_gene5548	2.314e-29	121.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR21617310_k127_2355553_16	525368.HMPREF0591_4488	9.674e-07	60.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,234FU@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_2355553_10	318424.EU78_18140	2.427e-33	140.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,234FU@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_2355553_4	1894.JOER01000016_gene5580	2.761e-65	245.0	COG1961@1|root,COG1961@2|Bacteria,2IEJ9@201174|Actinobacteria	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2355553_2	710111.FraQA3DRAFT_5555	1.474e-78	267.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ERS8@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	-	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K10907,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_2355553_12	1122611.KB903974_gene3022	1.703e-32	133.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4EFJ6@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_2355553_5	1394178.AWOO02000051_gene6045	7.535e-65	233.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4EFJ6@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_2355553_7	656024.FsymDg_2239	2.622e-50	192.0	COG4974@1|root,COG4974@2|Bacteria,2IBWD@201174|Actinobacteria,4EVIA@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_2355553_9	1054860.KB913030_gene1059	2.008e-43	167.0	COG1443@1|root,COG1443@2|Bacteria,2IFK1@201174|Actinobacteria	201174|Actinobacteria	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_2355553_0	1050202.KB913024_gene3133	2.798e-138	471.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,40818@622450|Actinopolysporales	201174|Actinobacteria	S	Protein of unknown function (DUF3533)	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3
SRR21617310_k127_2355553_8	1206720.BAFQ01000284_gene5986	3.238e-49	184.0	COG1131@1|root,COG1131@2|Bacteria,2GM8X@201174|Actinobacteria,4G9XE@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2355553_13	675635.Psed_5736	1.96e-29	128.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,4EF8H@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysin motif	-	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SRR21617310_k127_2355553_17	43759.JNWK01000002_gene6005	2.879e-05	53.0	2BF9F@1|root,3292B@2|Bacteria,2ISEN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
SRR21617310_k127_2355553_1	1120948.KB903247_gene4535	1.579e-104	348.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4DY1J@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRR21617310_k127_2355553_11	67352.JODS01000020_gene3861	6.312e-33	138.0	COG0500@1|root,COG2226@2|Bacteria,2GUTS@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_2355553_15	1449069.JMLO01000034_gene134	3.162e-14	83.0	COG3393@1|root,COG3393@2|Bacteria,2I2P8@201174|Actinobacteria,4G104@85025|Nocardiaceae	201174|Actinobacteria	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
SRR21617310_k127_2355553_6	981369.JQMJ01000004_gene796	5.31e-58	217.0	COG0477@1|root,COG2814@2|Bacteria,2IF5M@201174|Actinobacteria,2NM8R@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
SRR21617310_k127_2355553_18	1463825.JNXC01000040_gene5135	0.0004335	47.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR21617310_k127_2355553_3	1172179.AUKV01000005_gene5974	2.586e-74	262.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR21617310_k127_2363130_2	1254432.SCE1572_09945	3.483e-74	262.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR21617310_k127_2363130_5	1894.JOER01000044_gene6729	1.363e-45	175.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_2363130_7	40571.JOEA01000028_gene5465	4.674e-17	86.0	2BNZV@1|root,32HQ2@2|Bacteria,2H5IX@201174|Actinobacteria,4EB3P@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2363130_1	518766.Rmar_0239	5.348e-95	327.0	COG0430@1|root,COG0430@2|Bacteria	2|Bacteria	A	RNA-3'-phosphate cyclase activity	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
SRR21617310_k127_2363130_3	1121272.KB903259_gene6548	9.436e-58	211.0	COG0177@1|root,COG0177@2|Bacteria,2GNYB@201174|Actinobacteria,4D8QW@85008|Micromonosporales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2363130_6	1394178.AWOO02000096_gene8201	1.151e-23	111.0	2DM8J@1|root,32695@2|Bacteria,2I561@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2363130_0	671143.DAMO_0652	1.683e-206	662.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR21617310_k127_2363130_4	671143.DAMO_0654	5.036e-53	192.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR21617310_k127_2367355_0	937777.Deipe_0466	1.108e-46	187.0	COG3941@1|root,COG3941@2|Bacteria	2|Bacteria	O	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR21617310_k127_2370529_4	479432.Sros_2429	9.054e-171	550.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
SRR21617310_k127_2370529_5	644283.Micau_2783	1.458e-70	262.0	COG3208@1|root,COG3208@2|Bacteria,2I5FS@201174|Actinobacteria,4DMNR@85008|Micromonosporales	201174|Actinobacteria	Q	Lantibiotic dehydratase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lant_dehydr_N,Thioesterase
SRR21617310_k127_2370529_6	1173028.ANKO01000086_gene4	1.205e-24	120.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR21617310_k127_2370529_2	644283.Micau_2643	1.241e-278	884.0	COG3208@1|root,COG3208@2|Bacteria,2I5FS@201174|Actinobacteria,4DMNR@85008|Micromonosporales	201174|Actinobacteria	Q	Lantibiotic dehydratase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lant_dehydr_N,Thioesterase
SRR21617310_k127_2370529_1	1121272.KB903289_gene4070	2.847e-279	906.0	COG1020@1|root,COG1020@2|Bacteria,2H9ZW@201174|Actinobacteria,4D8PN@85008|Micromonosporales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_2370529_0	479432.Sros_2423	0.0	2025.0	COG1020@1|root,COG1028@1|root,COG3321@1|root,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria,4ER85@85012|Streptosporangiales	201174|Actinobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR21617310_k127_2370529_3	479432.Sros_2421	1.038e-188	617.0	COG1020@1|root,COG1020@2|Bacteria,2I9G0@201174|Actinobacteria	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_2381521_1	1429046.RR21198_5885	1.822e-36	151.0	COG0468@1|root,COG0468@2|Bacteria,2GP4G@201174|Actinobacteria,4FZUN@85025|Nocardiaceae	201174|Actinobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
SRR21617310_k127_2381521_2	571.MC52_29140	4.319e-05	48.0	COG3311@1|root,COG3311@2|Bacteria,1N5KM@1224|Proteobacteria,1S9H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Prophage CP4-57 regulatory protein (AlpA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
SRR21617310_k127_2381521_0	649747.HMPREF0083_04679	4.278e-37	157.0	COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,4HCR8@91061|Bacilli,274YJ@186822|Paenibacillaceae	91061|Bacilli	L	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR21617310_k127_2386272_4	1231185.BAMP01000029_gene437	2.413e-82	282.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,43IBA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_2386272_7	44060.JODL01000004_gene2487	1.235e-39	154.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2386272_6	882083.SacmaDRAFT_3110	9.603e-61	238.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria,4DZFG@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR21617310_k127_2386272_1	1463879.JOHP01000001_gene1481	1.296e-154	511.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR21617310_k127_2386272_3	485913.Krac_2150	3.013e-100	334.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	2|Bacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2386272_0	485913.Krac_2149	1.217e-227	728.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2G872@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR21617310_k127_2386272_5	1123023.JIAI01000018_gene2467	1.878e-69	244.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4E0ZX@85010|Pseudonocardiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	mtcA1	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR21617310_k127_2386272_8	1283299.AUKG01000002_gene4189	4.259e-36	158.0	COG1865@1|root,COG1865@2|Bacteria,2I8C5@201174|Actinobacteria,4CR70@84995|Rubrobacteria	84995|Rubrobacteria	S	Adenosylcobinamide amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CbiZ
SRR21617310_k127_2386272_2	1089549.AZUQ01000001_gene2403	1.907e-105	362.0	COG0079@1|root,COG2087@1|root,COG0079@2|Bacteria,COG2087@2|Bacteria,2I2ND@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	cobC	GO:0008150,GO:0040007	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,CbiG_C
SRR21617310_k127_239469_16	269800.Tfu_2081	1.869e-70	248.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4EFZJ@85012|Streptosporangiales	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR21617310_k127_239469_28	1463856.JOHY01000008_gene1046	9.037e-13	73.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR21617310_k127_239469_29	526225.Gobs_3159	1.268e-06	55.0	2EGGE@1|root,33A8E@2|Bacteria,2I1AI@201174|Actinobacteria,4ETI5@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_239469_0	1463887.KL589957_gene855	2.54e-315	989.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR21617310_k127_239469_26	369723.Strop_1829	1.448e-25	119.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4DD5I@85008|Micromonosporales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR21617310_k127_239469_19	697284.ERIC2_c27640	4.424e-58	224.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,26Q9M@186822|Paenibacillaceae	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR21617310_k127_239469_27	888056.HMPREF9062_1684	3.578e-23	111.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4D47B@85005|Actinomycetales	201174|Actinobacteria	E	shikimate dehydrogenase	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
SRR21617310_k127_239469_21	68570.DC74_4957	3.425e-38	160.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_239469_8	1121372.AULK01000003_gene257	8.528e-123	405.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4FQ55@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_239469_24	1380356.JNIK01000021_gene4567	1.953e-31	133.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4ESYI@85013|Frankiales	201174|Actinobacteria	NOU	peptidase A24A prepilin type IV	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
SRR21617310_k127_239469_2	471852.Tcur_2953	6.602e-154	496.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4EIB5@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR21617310_k127_239469_22	292459.STH1949	2.378e-37	147.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SRR21617310_k127_239469_13	762963.HMPREF9056_01957	1.117e-82	289.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4D3R5@85005|Actinomycetales	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR21617310_k127_239469_23	665942.HMPREF1022_01477	5.48e-37	151.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,2MBIR@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR21617310_k127_239469_12	1382304.JNIL01000001_gene226	1.401e-85	298.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27894@186823|Alicyclobacillaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR21617310_k127_239469_14	525909.Afer_1713	2.712e-75	258.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR21617310_k127_239469_25	40571.JOEA01000032_gene743	2.516e-31	136.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR21617310_k127_239469_6	479433.Caci_1823	1.173e-129	420.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria	201174|Actinobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR21617310_k127_239469_17	390989.JOEG01000012_gene3375	1.648e-69	258.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4DDB5@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_239469_11	66373.JOFQ01000028_gene4400	1.038e-87	300.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
SRR21617310_k127_239469_15	886293.Sinac_0913	1.598e-73	275.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR21617310_k127_239469_1	1122138.AQUZ01000090_gene3427	7.18e-205	663.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNJP@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_239469_20	258052.JNYV01000003_gene5038	9.431e-41	171.0	COG1309@1|root,COG1309@2|Bacteria,2GP91@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR21617310_k127_239469_10	2074.JNYD01000004_gene4951	5.711e-102	354.0	COG0395@1|root,COG0395@2|Bacteria,2IDQB@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR21617310_k127_239469_9	1394178.AWOO02000071_gene398	3.042e-103	351.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4EHFE@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR21617310_k127_239469_7	2074.JNYD01000004_gene4949	7.093e-129	428.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4E1T7@85010|Pseudonocardiales	201174|Actinobacteria	E	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
SRR21617310_k127_239469_4	1394178.AWOO02000071_gene396	3.641e-151	509.0	COG1653@1|root,COG1653@2|Bacteria,2IDWS@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_239469_18	693977.Deipr_1410	1.188e-67	237.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR21617310_k127_239469_5	471852.Tcur_3015	6.4e-136	446.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4EH29@85012|Streptosporangiales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR21617310_k127_239469_3	1211815.CBYP010000005_gene226	6.652e-153	509.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4ERCY@85013|Frankiales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR21617310_k127_2395012_0	1116232.AHBF01000036_gene5622	1.603e-21	101.0	2B7FY@1|root,320JT@2|Bacteria,2H4AU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2395012_1	1151126.AQYI01000004_gene921	2.262e-21	106.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FMIB@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_2395940_3	266117.Rxyl_0635	3.096e-54	197.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria,4CPSC@84995|Rubrobacteria	84995|Rubrobacteria	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
SRR21617310_k127_2395940_0	1380390.JIAT01000015_gene5771	1.472e-193	620.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4CPS0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
SRR21617310_k127_2395940_1	526225.Gobs_0561	1.754e-96	332.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4ES1Q@85013|Frankiales	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR21617310_k127_2395940_4	42256.RradSPS_0810	1.607e-43	168.0	COG5446@1|root,COG5446@2|Bacteria,2H6Y9@201174|Actinobacteria,4CQA2@84995|Rubrobacteria	84995|Rubrobacteria	S	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
SRR21617310_k127_2395940_5	42256.RradSPS_0809	2.274e-14	78.0	2DFSU@1|root,2ZT0P@2|Bacteria	2|Bacteria	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR21617310_k127_2395940_2	1449353.JQMQ01000005_gene5697	3.357e-63	220.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria	201174|Actinobacteria	L	Pfam NUDIX	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_2396825_5	1347368.HG964403_gene4216	2.939e-05	48.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HUAD@91061|Bacilli,1ZSBU@1386|Bacillus	91061|Bacilli	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR21617310_k127_2396825_4	138119.DSY0967	4.055e-55	201.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24R48@186801|Clostridia,2637S@186807|Peptococcaceae	186801|Clostridia	S	PFAM Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR21617310_k127_2396825_3	1120983.KB894577_gene3578	2.663e-61	229.0	COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR21617310_k127_2396825_6	1123023.JIAI01000001_gene6850	0.0002493	52.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2396825_2	639283.Snov_0200	1.862e-69	252.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3F1EG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR21617310_k127_2396825_0	351607.Acel_0894	2.015e-155	501.0	COG5276@1|root,COG5276@2|Bacteria,2IH2N@201174|Actinobacteria	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR21617310_k127_2396825_1	1120949.KB903299_gene6018	5.335e-95	321.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4D96Y@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR21617310_k127_2400668_1	298653.Franean1_2549	4.021e-05	52.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria	201174|Actinobacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR21617310_k127_240378_2	395494.Galf_2723	2.3e-07	55.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_240378_3	196162.Noca_3783	0.0005507	48.0	COG0695@1|root,COG0695@2|Bacteria,2GS68@201174|Actinobacteria,4DVZ4@85009|Propionibacteriales	201174|Actinobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR21617310_k127_240378_1	1171373.PACID_01680	2.854e-33	137.0	COG1225@1|root,COG1225@2|Bacteria,2IGFI@201174|Actinobacteria,4DRG7@85009|Propionibacteriales	201174|Actinobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR21617310_k127_240378_0	247156.PNF1_830	3.609e-117	382.0	COG2020@1|root,COG2020@2|Bacteria,2IE57@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR21617310_k127_2407220_0	1463825.JNXC01000019_gene6477	2.315e-74	257.0	COG0343@1|root,COG0343@2|Bacteria,2I9KU@201174|Actinobacteria,4DZ45@85010|Pseudonocardiales	201174|Actinobacteria	J	queuine tRNA-ribosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2407220_1	1227349.C170_16555	6.327e-06	51.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRT8@91061|Bacilli,26ZRU@186822|Paenibacillaceae	91061|Bacilli	K	transcriptional	sinR	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR21617310_k127_2410524_1	479432.Sros_4203	3.614e-144	475.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4ENKK@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR21617310_k127_2410524_0	1449355.JQNR01000005_gene5301	1.769e-285	907.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR21617310_k127_242437_0	1463887.KL589968_gene7390	5.739e-54	197.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR21617310_k127_242437_1	419947.MRA_2192	6.234e-19	92.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,239QV@1762|Mycobacteriaceae	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_2425478_1	1123024.AUII01000013_gene380	3.645e-103	352.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4E8SB@85010|Pseudonocardiales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR21617310_k127_2425478_2	1463900.JOIX01000006_gene743	4.288e-71	257.0	COG0740@1|root,COG0740@2|Bacteria,2IGS3@201174|Actinobacteria	201174|Actinobacteria	OU	Belongs to the peptidase S14 family	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease,Mu-like_Pro
SRR21617310_k127_2425478_0	479433.Caci_2852	6.697e-129	430.0	COG4653@1|root,COG4653@2|Bacteria	2|Bacteria	G	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR21617310_k127_2427804_0	1380390.JIAT01000009_gene669	9.04e-146	496.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_2428390_1	471852.Tcur_1491	1.246e-209	689.0	COG1196@1|root,COG4913@1|root,COG1196@2|Bacteria,COG4913@2|Bacteria,2GK6F@201174|Actinobacteria	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR21617310_k127_2428390_3	471852.Tcur_1492	1.149e-145	474.0	28HUD@1|root,2Z813@2|Bacteria,2ICFF@201174|Actinobacteria,4EMEJ@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
SRR21617310_k127_2428390_2	471852.Tcur_1493	5.005e-184	606.0	2CC51@1|root,2Z7IU@2|Bacteria,2GM14@201174|Actinobacteria,4ENFW@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
SRR21617310_k127_2428390_4	1146883.BLASA_2734	7.105e-83	286.0	COG4279@1|root,COG4279@2|Bacteria,2GIYW@201174|Actinobacteria	201174|Actinobacteria	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR21617310_k127_2428390_0	263358.VAB18032_27651	0.0	1079.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DBI7@85008|Micromonosporales	201174|Actinobacteria	KL	Non-specific serine threonine protein kinase	helZ	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR21617310_k127_2428390_5	463191.SSEG_07643	5.168e-17	80.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR21617310_k127_2432162_4	1283299.AUKG01000001_gene2437	1.162e-59	219.0	COG3899@1|root,COG3899@2|Bacteria,2HFRA@201174|Actinobacteria,4CR76@84995|Rubrobacteria	84995|Rubrobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR21617310_k127_2432162_13	234267.Acid_5780	5.276e-18	95.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
SRR21617310_k127_2432162_6	1114856.C496_06587	1.163e-30	137.0	2CG7F@1|root,2N5FI@2157|Archaea,2XZIM@28890|Euryarchaeota,23X4N@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2432162_0	296591.Bpro_1369	1.44e-188	606.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VJHX@28216|Betaproteobacteria,4ACRX@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
SRR21617310_k127_2432162_9	561175.KB894093_gene3651	9.216e-23	104.0	COG3832@1|root,COG3832@2|Bacteria,2II0Q@201174|Actinobacteria,4EP5G@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_2432162_5	1298880.AUEV01000023_gene5218	4.707e-55	204.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_2432162_10	395961.Cyan7425_1594	4.438e-22	101.0	COG4977@1|root,COG4977@2|Bacteria,1GR33@1117|Cyanobacteria	1117|Cyanobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR21617310_k127_2432162_8	1227497.C491_08393	4.879e-27	118.0	COG0693@1|root,arCOG00769@2157|Archaea,2XV38@28890|Euryarchaeota,23RWT@183963|Halobacteria	183963|Halobacteria	S	intracellular protease amidase	araC	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR21617310_k127_2432162_3	1068980.ARVW01000001_gene6265	6.753e-60	212.0	COG0454@1|root,COG0456@2|Bacteria,2IM2R@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR21617310_k127_2432162_7	469371.Tbis_2976	2.089e-27	115.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4E5PP@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR21617310_k127_2432162_2	106370.Francci3_4167	2.095e-71	246.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_2432162_11	1120949.KB903312_gene606	1.809e-21	97.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_2432162_1	263358.VAB18032_16165	2.663e-83	282.0	2EFCG@1|root,3395D@2|Bacteria,2H5YV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2432162_12	43759.JNWK01000020_gene7353	1.103e-18	95.0	COG0125@1|root,COG0125@2|Bacteria,2ICYS@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR21617310_k127_2435572_4	479433.Caci_0093	6.385e-123	403.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_2435572_2	1157637.KB892098_gene2047	3.358e-128	417.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_2435572_5	446468.Ndas_5419	2.469e-117	396.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4EFSQ@85012|Streptosporangiales	201174|Actinobacteria	C	e3 binding domain	bkdH	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_2435572_10	1313172.YM304_28820	5.516e-14	84.0	COG0741@1|root,COG0741@2|Bacteria,2IF18@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR21617310_k127_2435572_6	530564.Psta_0358	2.194e-103	349.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR21617310_k127_2435572_1	1120948.KB903217_gene1079	1.002e-136	452.0	COG0530@1|root,COG0530@2|Bacteria,2GP6H@201174|Actinobacteria,4E18G@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR21617310_k127_2435572_3	981369.JQMJ01000004_gene5951	2.085e-127	422.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,2NGS9@228398|Streptacidiphilus	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR21617310_k127_2435572_7	864069.MicloDRAFT_00005280	7.296e-75	268.0	COG1215@1|root,COG1215@2|Bacteria,1MXXV@1224|Proteobacteria,2TU9R@28211|Alphaproteobacteria,1JU7Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	nodC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006807,GO:0007155,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022607,GO:0022610,GO:0030198,GO:0030203,GO:0030212,GO:0030213,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043062,GO:0043170,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0045226,GO:0046379,GO:0046394,GO:0050501,GO:0071704,GO:0071840,GO:0071944,GO:0085029,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510	2.4.1.212	ko:K00752,ko:K14666	-	M00664	-	-	ko00000,ko00002,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Chitin_synth_2,Glyco_trans_2_3,Glycos_transf_2
SRR21617310_k127_2435572_0	106370.Francci3_0048	1.479e-143	496.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR21617310_k127_2435572_9	991905.SL003B_0890	2.419e-34	143.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TUA2@28211|Alphaproteobacteria,4BQ3N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	bacC	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR21617310_k127_2435572_8	390989.JOEG01000021_gene2652	5.369e-46	175.0	COG0664@1|root,COG0664@2|Bacteria,2I7B7@201174|Actinobacteria,4DAN8@85008|Micromonosporales	201174|Actinobacteria	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR21617310_k127_2441000_1	1068980.ARVW01000001_gene5349	5.918e-62	214.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4E43G@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR21617310_k127_2441000_2	373994.Riv7116_4452	5.31e-18	85.0	COG2518@1|root,COG2518@2|Bacteria,1G4C3@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR21617310_k127_2441000_3	1869.MB27_18645	7.199e-06	51.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4DG1B@85008|Micromonosporales	201174|Actinobacteria	O	protein-L-isoaspartate(D-aspartate) O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Lant_dehydr_C,PCMT
SRR21617310_k127_2441000_0	2002.JOEQ01000003_gene2528	1.029e-179	577.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4EK91@85012|Streptosporangiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2443478_2	1116232.AHBF01000137_gene1929	1.142e-46	188.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria	201174|Actinobacteria	S	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR21617310_k127_2443478_1	479432.Sros_3911	1.456e-118	403.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4EFIG@85012|Streptosporangiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR21617310_k127_2443478_0	1123251.ATWM01000004_gene1974	1.178e-174	558.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR21617310_k127_2444647_0	690597.JH730935_gene3274	8.995e-120	392.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1YQ3T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	I	synthetase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR21617310_k127_2444647_4	67356.KL575612_gene4956	1.212e-34	145.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_2444647_5	591159.ACEZ01000200_gene2462	1.316e-25	113.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_2444647_7	1528106.JRJE01000031_gene3674	2.94e-08	56.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR21617310_k127_2444647_1	1394178.AWOO02000010_gene4157	9.998e-108	366.0	COG3858@1|root,COG3858@2|Bacteria,2GM95@201174|Actinobacteria,4EHXR@85012|Streptosporangiales	201174|Actinobacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR21617310_k127_2444647_3	471852.Tcur_3838	7.311e-58	211.0	COG2091@1|root,COG2091@2|Bacteria,2IQ65@201174|Actinobacteria,4EJHZ@85012|Streptosporangiales	201174|Actinobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR21617310_k127_2444647_6	1125700.HMPREF9195_01800	8.151e-17	92.0	COG1196@1|root,COG1196@2|Bacteria,2J7QP@203691|Spirochaetes	203691|Spirochaetes	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR21617310_k127_2444647_2	926550.CLDAP_31780	1.964e-82	284.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR21617310_k127_2444647_8	326427.Cagg_0457	0.0007442	53.0	COG1287@1|root,COG1287@2|Bacteria,2GA02@200795|Chloroflexi,377K4@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2450654_0	2002.JOEQ01000013_gene5478	1.028e-229	732.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR21617310_k127_2450654_3	1123319.AUBE01000041_gene6046	6.214e-105	346.0	COG0262@1|root,COG0262@2|Bacteria,2IF6H@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_2450654_4	1278073.MYSTI_01573	1.498e-102	341.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_2450654_6	110319.CF8_0505	6.656e-74	253.0	COG0262@1|root,COG0262@2|Bacteria,2IGE7@201174|Actinobacteria,4DUWE@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_2450654_2	2002.JOEQ01000052_gene8364	3.241e-111	387.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4EGDH@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR21617310_k127_2450654_5	646529.Desaci_0611	7.486e-75	263.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,266V6@186807|Peptococcaceae	186801|Clostridia	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.45,4.2.1.46,5.1.3.2	ko:K01709,ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02426,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_2450654_1	298653.Franean1_7278	9.978e-178	597.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR21617310_k127_2450654_7	1121928.AUHE01000017_gene124	4.035e-06	51.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4GB19@85026|Gordoniaceae	201174|Actinobacteria	S	Pirin C-terminal cupin domain	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR21617310_k127_2456566_3	1172180.KB911804_gene1119	8.851e-08	56.0	2F6TK@1|root,33Z9R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2456566_1	1089546.AQUI01000002_gene165	1.56e-39	156.0	COG5412@1|root,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,40AC1@622450|Actinopolysporales	201174|Actinobacteria	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_245865_4	1380370.JIBA01000014_gene2146	6.769e-07	56.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4FHE6@85021|Intrasporangiaceae	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR21617310_k127_245865_3	1306174.JODP01000006_gene3804	1.362e-69	244.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_245865_2	479434.Sthe_2181	4.439e-84	301.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR21617310_k127_245865_0	358823.DF19_02900	1.632e-113	383.0	COG1167@1|root,COG1167@2|Bacteria,2GM6I@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	ptsJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR21617310_k127_245865_5	1229780.BN381_130143	7.294e-06	54.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_245865_1	485916.Dtox_2146	7.056e-91	315.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR21617310_k127_2459654_0	882083.SacmaDRAFT_4134	2.164e-28	132.0	COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2459654_2	694430.Natoc_0521	1.856e-06	61.0	COG0717@1|root,COG1372@1|root,arCOG03146@1|root,arCOG03145@2157|Archaea,arCOG03146@2157|Archaea,arCOG04048@2157|Archaea,2XTSH@28890|Euryarchaeota,23S4X@183963|Halobacteria	183963|Halobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
SRR21617310_k127_2459654_1	446470.Snas_6269	1.412e-25	123.0	COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2460420_0	1449976.KALB_3752	3.852e-55	198.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4E0C4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR21617310_k127_2460420_1	591158.SSMG_07066	4.774e-53	202.0	COG1073@1|root,COG1073@2|Bacteria,2II3X@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_2460420_2	1120949.KB903339_gene7998	1.352e-29	118.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4D97N@85008|Micromonosporales	201174|Actinobacteria	S	Zinc-binding dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_2462322_5	1248917.ANFX01000010_gene203	4.94e-14	82.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2K1AX@204457|Sphingomonadales	204457|Sphingomonadales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR21617310_k127_2462322_2	2002.JOEQ01000008_gene1029	8.363e-42	159.0	COG4276@1|root,COG4276@2|Bacteria,2ISSK@201174|Actinobacteria,4EP45@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_2462322_1	345341.KUTG_02457	1.298e-48	182.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,2ICCW@201174|Actinobacteria	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR21617310_k127_2462322_4	1382356.JQMP01000004_gene527	5.664e-15	80.0	2F7FP@1|root,33ZWF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2462322_3	1123258.AQXZ01000014_gene4805	8.486e-38	149.0	COG2020@1|root,COG2020@2|Bacteria,2HHZT@201174|Actinobacteria,4G1XJ@85025|Nocardiaceae	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SRR21617310_k127_2462322_0	66897.DJ64_22475	7.793e-75	258.0	COG0500@1|root,COG2226@2|Bacteria,2GKH6@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_2465357_0	469371.Tbis_1953	5.953e-134	442.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR21617310_k127_2465357_2	1429046.RR21198_0029	4.6e-104	347.0	COG2267@1|root,COG2267@2|Bacteria,2I3KS@201174|Actinobacteria,4G9UP@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR21617310_k127_2465357_9	284031.JNXD01000020_gene7455	0.0001919	44.0	COG0346@1|root,COG0346@2|Bacteria,2IM20@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2465357_8	134676.ACPL_4347	0.0001026	48.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2465357_6	1121877.JQKF01000039_gene1843	4.66e-11	65.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
SRR21617310_k127_2465357_3	1449353.JQMQ01000005_gene1672	9.459e-89	301.0	COG1290@1|root,COG1290@2|Bacteria,2HG31@201174|Actinobacteria,2NHWQ@228398|Streptacidiphilus	201174|Actinobacteria	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_2465357_1	1449347.JQLN01000007_gene1837	2.263e-105	361.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
SRR21617310_k127_2465357_7	68570.DC74_442	5.194e-08	60.0	COG0110@1|root,COG0110@2|Bacteria,2I8TI@201174|Actinobacteria	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
SRR21617310_k127_2465357_4	134676.ACPL_1352	2.249e-62	232.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4D9U9@85008|Micromonosporales	201174|Actinobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR21617310_k127_2474237_8	748247.AZKH_p0336	3.299e-06	58.0	COG4447@1|root,COG4447@2|Bacteria,1R84R@1224|Proteobacteria,2VMQ1@28216|Betaproteobacteria,2KXPY@206389|Rhodocyclales	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR21617310_k127_2474237_7	100226.SCO3709	1.503e-35	143.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2474237_1	345341.KUTG_00500	2.595e-112	374.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4E0WZ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR21617310_k127_2474237_4	1095767.CAHD01000200_gene2346	1.011e-69	260.0	COG1131@1|root,COG1131@2|Bacteria,2IH64@201174|Actinobacteria,4F2FJ@85016|Cellulomonadaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2474237_3	1043493.BBLU01000014_gene1317	2.745e-79	289.0	COG1131@1|root,COG1131@2|Bacteria,2ICIF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2474237_6	391037.Sare_3404	3.217e-54	198.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4DB3G@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2474237_0	1121946.AUAX01000041_gene4884	5.058e-195	637.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4D8HA@85008|Micromonosporales	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR21617310_k127_2474237_2	1048339.KB913029_gene4377	4.942e-93	330.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_2474237_5	1463857.JOFZ01000012_gene1679	7.462e-67	246.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR21617310_k127_2474502_0	656024.FsymDg_3493	1.359e-99	350.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4ETDB@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SRR21617310_k127_2474502_1	1713.JOFV01000009_gene289	1.586e-69	251.0	COG2382@1|root,COG2382@2|Bacteria,2I2KB@201174|Actinobacteria	201174|Actinobacteria	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR21617310_k127_2476903_4	469383.Cwoe_2152	8.069e-57	201.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4CSNK@84995|Rubrobacteria	84995|Rubrobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding_C_2
SRR21617310_k127_2476903_5	1122138.AQUZ01000012_gene6041	8.057e-46	173.0	2C1EG@1|root,2Z7MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2476903_7	1122138.AQUZ01000012_gene6041	1.259e-05	55.0	2C1EG@1|root,2Z7MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2476903_1	1122939.ATUD01000005_gene2560	3.423e-119	405.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4CPG0@84995|Rubrobacteria	84995|Rubrobacteria	P	TOBE-like domain	-	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
SRR21617310_k127_2476903_2	1283299.AUKG01000003_gene287	8.789e-87	296.0	COG4208@1|root,COG4208@2|Bacteria,2GMTK@201174|Actinobacteria,4CS5G@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR21617310_k127_2476903_3	1394178.AWOO02000026_gene5112	3.001e-83	289.0	COG0555@1|root,COG0555@2|Bacteria,2I4C5@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
SRR21617310_k127_2476903_0	525904.Tter_2326	1.401e-119	392.0	COG1613@1|root,COG1613@2|Bacteria,2NQGY@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SRR21617310_k127_2482367_5	525368.HMPREF0591_1887	5.419e-05	51.0	COG2865@1|root,COG2865@2|Bacteria,2II99@201174|Actinobacteria,23CS3@1762|Mycobacteriaceae	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR21617310_k127_2482367_3	682795.AciX8_3093	2.535e-07	62.0	2EZMH@1|root,33SSN@2|Bacteria,3Y6QX@57723|Acidobacteria,2JM7A@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2482367_2	408672.NBCG_01613	1.092e-42	162.0	COG1396@1|root,COG1396@2|Bacteria,2IPA2@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2482367_1	1214242.B446_27610	7.198e-61	217.0	COG2856@1|root,COG2856@2|Bacteria,2IK1U@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR21617310_k127_2482367_4	1298863.AUEP01000003_gene2843	1.805e-06	59.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4DP9I@85009|Propionibacteriales	201174|Actinobacteria	K	RNA polymerase, sigma 28 subunit, SigD FliA WhiG	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_2482367_0	1120950.KB892822_gene589	2.252e-96	329.0	COG4422@1|root,COG4422@2|Bacteria,2GJHQ@201174|Actinobacteria,4DQRH@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM phage Gp37Gp68 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR21617310_k127_2484611_0	106370.Francci3_3057	2.039e-310	966.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4ESAA@85013|Frankiales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR21617310_k127_2484611_2	326424.FRAAL5148	6.761e-103	353.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4ES11@85013|Frankiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR21617310_k127_2484611_3	58123.JOFJ01000005_gene1587	2.038e-38	154.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4EJJZ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2484611_4	1463856.JOHY01000033_gene2903	5.722e-23	106.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_2484611_1	1123319.AUBE01000029_gene5204	1.997e-173	566.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_2484611_5	1415166.NONO_c21950	5.934e-20	90.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4FUKU@85025|Nocardiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_2484765_0	1254432.SCE1572_09945	5.067e-36	148.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR21617310_k127_2491430_2	1123023.JIAI01000002_gene4586	2.668e-82	280.0	COG2318@1|root,COG2318@2|Bacteria,2HRVG@201174|Actinobacteria,4EB71@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_2491430_0	1209984.BN978_05492	4.743e-95	319.0	COG4974@1|root,COG4974@2|Bacteria,2GK8T@201174|Actinobacteria,2349N@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_2491430_6	298653.Franean1_2617	2.053e-25	117.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_1	1172186.KB911474_gene3871	2.962e-84	299.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria,2385C@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_11	1268303.RHODMAR_3509	2.827e-13	76.0	2CA8D@1|root,32RQU@2|Bacteria,2GQ8V@201174|Actinobacteria,4G1J3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_5	1206735.BAGG01000234_gene5757	3.908e-29	134.0	COG0582@1|root,COG0582@2|Bacteria,2GK5Z@201174|Actinobacteria,4G0AD@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_9	247156.PNF1_890	8.32e-20	97.0	COG0582@1|root,COG0582@2|Bacteria,2GK5Z@201174|Actinobacteria,4G0AD@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_3	1206735.BAGG01000234_gene5757	8.8e-67	236.0	COG0582@1|root,COG0582@2|Bacteria,2GK5Z@201174|Actinobacteria,4G0AD@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_4	1209984.BN978_05496	4.503e-41	167.0	COG0582@1|root,COG0582@2|Bacteria,2GK5Z@201174|Actinobacteria,232M2@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_7	1209984.BN978_05497	1.095e-21	101.0	2B2WI@1|root,31VH3@2|Bacteria,2IRFC@201174|Actinobacteria,23BEQ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2491430_10	682795.AciX8_2290	1.252e-13	83.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL,TIG
SRR21617310_k127_2493132_2	1313172.YM304_40840	8.726e-118	393.0	COG1201@1|root,COG1201@2|Bacteria,2I6VR@201174|Actinobacteria,4CNBF@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DEAD-like helicases superfamily	-	-	-	ko:K03724,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR21617310_k127_2493132_0	105420.BBPO01000020_gene5596	2.608e-144	469.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,2NFCN@228398|Streptacidiphilus	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR21617310_k127_2493132_6	479432.Sros_8856	8.994e-62	213.0	COG1695@1|root,COG1695@2|Bacteria,2IM8U@201174|Actinobacteria,4EPD2@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR21617310_k127_2493132_7	2002.JOEQ01000001_gene4872	1.083e-55	196.0	COG4817@1|root,COG4817@2|Bacteria,2IM9H@201174|Actinobacteria,4EK39@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1048)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1048
SRR21617310_k127_2493132_8	1068980.ARVW01000001_gene5344	3.048e-17	91.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4E229@85010|Pseudonocardiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2493132_3	1283283.ATXA01000020_gene1309	3.678e-113	370.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2493132_1	1429046.RR21198_2052	3.07e-140	447.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4FW2N@85025|Nocardiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_2493132_4	257310.BB0718	4.927e-80	280.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VZBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
SRR21617310_k127_2493132_10	1463900.JOIX01000041_gene1990	7.723e-08	56.0	2B2SW@1|root,31BZZ@2|Bacteria,2HAPQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2493132_5	105425.BBPL01000071_gene3732	2.162e-68	252.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_2493132_9	656024.FsymDg_0487	1.635e-14	82.0	2BH5R@1|root,32B6W@2|Bacteria,2GYG1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2499743_3	500153.JOEK01000017_gene3274	1.494e-101	336.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	yajO	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2499743_5	1121946.AUAX01000002_gene56	3.761e-56	201.0	COG1733@1|root,COG1733@2|Bacteria,2GNVK@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR21617310_k127_2499743_10	1100720.ALKN01000007_gene2812	9.258e-16	89.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2WGT1@28216|Betaproteobacteria,4AK4T@80864|Comamonadaceae	28216|Betaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_2499743_4	1163409.UUA_00440	9.738e-86	296.0	COG1275@1|root,COG1275@2|Bacteria,1MXP2@1224|Proteobacteria,1RR76@1236|Gammaproteobacteria,1X5E7@135614|Xanthomonadales	135614|Xanthomonadales	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
SRR21617310_k127_2499743_2	1380370.JIBA01000013_gene1248	2.036e-106	349.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4FFNE@85021|Intrasporangiaceae	201174|Actinobacteria	C	Nitrate reductase	narI	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	1.7.5.1	ko:K00370,ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iNJ661.Rv1164	Nitrate_red_gam
SRR21617310_k127_2499743_7	561175.KB894096_gene482	5.375e-55	215.0	COG2180@1|root,COG2180@2|Bacteria,2IM8P@201174|Actinobacteria,4ENX1@85012|Streptosporangiales	201174|Actinobacteria	C	Nitrate reductase delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRR21617310_k127_2499743_1	1123023.JIAI01000003_gene3082	1.289e-316	974.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4DYH1@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
SRR21617310_k127_2499743_0	675635.Psed_4300	0.0	2051.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4DZ13@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008940,GO:0009056,GO:0009628,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016491,GO:0016661,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036293,GO:0036294,GO:0042126,GO:0042128,GO:0042221,GO:0042493,GO:0043436,GO:0043602,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070482,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071453,GO:0071704,GO:0071731,GO:0071732,GO:0071941,GO:0071944,GO:0097366,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:2001057	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
SRR21617310_k127_2499743_6	1386089.N865_10090	5.583e-56	205.0	COG1388@1|root,COG1388@2|Bacteria,2IKMC@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2499743_9	1463857.JOFZ01000001_gene6064	1.822e-18	98.0	COG1595@1|root,COG1595@2|Bacteria,2IG3F@201174|Actinobacteria	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR21617310_k127_2499743_11	397278.JOJN01000002_gene617	6.201e-13	78.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4DQM4@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR21617310_k127_2500381_0	103733.JNYO01000007_gene5176	1.319e-39	150.0	COG2856@1|root,COG2856@2|Bacteria,2IFC9@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR21617310_k127_2500381_1	1463885.KL578371_gene5192	1.433e-24	112.0	COG2856@1|root,COG2856@2|Bacteria,2IFC9@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR21617310_k127_2501037_0	243160.BMAA0054	1.027e-37	152.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,1K79X@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR21617310_k127_2501037_1	1121946.AUAX01000004_gene675	2.969e-29	122.0	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,4DFTQ@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR21617310_k127_2501037_2	469383.Cwoe_1973	1.582e-28	124.0	COG4709@1|root,COG4709@2|Bacteria,2GXX9@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2501037_3	1120950.KB892790_gene2070	1.237e-15	77.0	COG1695@1|root,COG1695@2|Bacteria,2GRHC@201174|Actinobacteria,4DV0A@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR21617310_k127_2501037_4	469371.Tbis_0410	9.727e-10	62.0	COG0517@1|root,COG0517@2|Bacteria,2I3TG@201174|Actinobacteria,4EC77@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_2501327_7	582515.KR51_00017720	4.597e-90	318.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_2501327_14	118163.Ple7327_0250	4.604e-61	222.0	COG1216@1|root,COG1216@2|Bacteria,1GHEG@1117|Cyanobacteria,3VNI7@52604|Pleurocapsales	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_2501327_1	1348663.KCH_16700	6.328e-137	447.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,2M388@2063|Kitasatospora	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR21617310_k127_2501327_5	67352.JODS01000028_gene2339	2.401e-93	314.0	COG1682@1|root,COG1682@2|Bacteria,2IC4Y@201174|Actinobacteria	201174|Actinobacteria	GM	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_2501327_4	1348663.KCH_16790	8.219e-99	337.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,2M23E@2063|Kitasatospora	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2501327_16	710696.Intca_2630	4.282e-36	151.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,4FFTW@85021|Intrasporangiaceae	201174|Actinobacteria	M	galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2501327_10	67352.JODS01000028_gene2344	3.436e-86	301.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2501327_11	452652.KSE_16450	2.018e-76	268.0	COG3153@1|root,COG3153@2|Bacteria,2I8ZE@201174|Actinobacteria,2M4H8@2063|Kitasatospora	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR21617310_k127_2501327_9	67352.JODS01000028_gene2346	2.615e-86	303.0	28IEF@1|root,2Z8GG@2|Bacteria,2I8UG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2501327_15	1146883.BLASA_0348	1.923e-42	169.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Polysacc_deac_1
SRR21617310_k127_2501327_8	67352.JODS01000028_gene2329	1.244e-88	324.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2501327_17	293826.Amet_0341	5.98e-31	141.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,36F6R@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR21617310_k127_2501327_6	383372.Rcas_3084	2.859e-91	334.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR21617310_k127_2501327_3	452652.KSE_16470	1.322e-108	367.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,2M4SG@2063|Kitasatospora	201174|Actinobacteria	E	DegT DnrJ EryC1 StrS aminotransferase family	eryCIV	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR21617310_k127_2501327_13	1173028.ANKO01000018_gene1166	5.289e-73	250.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR21617310_k127_2501327_0	479432.Sros_0639	5.747e-202	642.0	COG4310@1|root,COG4310@2|Bacteria,2GK72@201174|Actinobacteria,4EMBW@85012|Streptosporangiales	201174|Actinobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
SRR21617310_k127_2501327_12	414684.RC1_3995	5.318e-75	258.0	COG2120@1|root,COG2120@2|Bacteria,1MX2V@1224|Proteobacteria,2TT5F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR21617310_k127_2501327_2	272134.KB731324_gene1964	1.874e-114	377.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR21617310_k127_2501327_18	1356852.N008_01550	7.156e-10	62.0	COG2227@1|root,COG2227@2|Bacteria,4NK04@976|Bacteroidetes,47NG1@768503|Cytophagia	976|Bacteroidetes	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR21617310_k127_2510225_3	1394178.AWOO02000069_gene306	8.616e-194	611.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4EI2Q@85012|Streptosporangiales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR21617310_k127_2510225_0	1120936.KB907217_gene3684	2.25e-247	774.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4EHDG@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxyl transferase domain	accD2	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR21617310_k127_2510225_1	1120948.KB903247_gene4611	2.716e-205	672.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZTM@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR21617310_k127_2510225_5	882083.SacmaDRAFT_5371	3.413e-91	309.0	COG1024@1|root,COG1024@2|Bacteria,2I97K@201174|Actinobacteria,4E2DI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR21617310_k127_2510225_4	882083.SacmaDRAFT_5380	6.478e-173	550.0	COG1960@1|root,COG1960@2|Bacteria,2GNFB@201174|Actinobacteria,4DY21@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_2510225_2	1048339.KB913029_gene504	4.994e-202	644.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4ES6B@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_2510225_6	1218075.BAYA01000028_gene5734	2.913e-10	61.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2VPWN@28216|Betaproteobacteria,1KAPB@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_251188_1	35754.JNYJ01000022_gene8184	1.116e-145	467.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4D9GX@85008|Micromonosporales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR21617310_k127_251188_0	35754.JNYJ01000022_gene8181	2.041e-199	628.0	COG1167@1|root,COG1167@2|Bacteria,2I310@201174|Actinobacteria,4DBP8@85008|Micromonosporales	201174|Actinobacteria	EK	PFAM aminotransferase, class I and II	-	-	2.6.1.103	ko:K16423	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06626,R06634	RC00006,RC01104	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR21617310_k127_251188_3	644283.Micau_3722	9.482e-73	252.0	COG2091@1|root,COG2091@2|Bacteria,2I13S@201174|Actinobacteria,4DF4D@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR21617310_k127_251188_2	1463934.JOCF01000016_gene3724	4.081e-97	327.0	COG4627@1|root,COG4627@2|Bacteria,2GP9I@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_251188_4	35754.JNYJ01000022_gene8172	4.363e-33	128.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DBSH@85008|Micromonosporales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_2513387_5	222534.KB893749_gene4470	6.902e-09	59.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR21617310_k127_2513387_1	350058.Mvan_2212	1.242e-85	295.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,233JN@1762|Mycobacteriaceae	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_2513387_3	1121877.JQKF01000033_gene2002	7.64e-20	93.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_2513387_0	136273.GY22_10795	5.506e-126	414.0	COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria,1W7GX@1268|Micrococcaceae	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR21617310_k127_2513387_2	1487953.JMKF01000001_gene491	1.661e-36	143.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
SRR21617310_k127_2513387_6	1048339.KB913029_gene483	7.274e-08	57.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4EUE5@85013|Frankiales	201174|Actinobacteria	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_2513387_4	1120950.KB892778_gene1035	6.769e-18	85.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4DP1Y@85009|Propionibacteriales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_2521335_2	222534.KB893786_gene212	1.137e-21	96.0	2DXHB@1|root,34515@2|Bacteria,2GXDY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2521335_1	1120950.KB892744_gene2805	1.505e-41	158.0	2DQM7@1|root,32UPC@2|Bacteria,2IFJG@201174|Actinobacteria,4DW2D@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2521335_0	994479.GL877878_gene1830	1.531e-90	308.0	COG1396@1|root,COG1396@2|Bacteria,2GK3V@201174|Actinobacteria,4E2YW@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2521877_5	1121946.AUAX01000016_gene4621	0.0004308	46.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_2521877_4	1121946.AUAX01000016_gene4621	7.267e-09	59.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_2521877_2	1463887.KL589967_gene6543	8.632e-34	132.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR21617310_k127_2521877_0	1237500.ANBA01000020_gene3196	7.108e-83	286.0	COG1413@1|root,COG1413@2|Bacteria,2GKYF@201174|Actinobacteria,4EP63@85012|Streptosporangiales	201174|Actinobacteria	C	Domain of unknown function (DUF4132)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132
SRR21617310_k127_2521877_1	1237500.ANBA01000020_gene3195	1.977e-72	259.0	28M5V@1|root,2ZAJJ@2|Bacteria,2GJNZ@201174|Actinobacteria,4EMVE@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2521877_3	1237500.ANBA01000020_gene3195	4.959e-20	102.0	28M5V@1|root,2ZAJJ@2|Bacteria,2GJNZ@201174|Actinobacteria,4EMVE@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2522347_0	1463825.JNXC01000009_gene1490	9.869e-57	211.0	COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria	201174|Actinobacteria	L	DNA (cytosine-5-)-methyltransferase activity	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR21617310_k127_25435_11	543632.JOJL01000030_gene3438	2.03e-08	56.0	28MFE@1|root,2ZASW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR21617310_k127_25435_10	33876.JNXY01000039_gene6685	4.263e-40	152.0	2DMB2@1|root,32UGJ@2|Bacteria,2I1VY@201174|Actinobacteria,4DKEK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_25435_8	298653.Franean1_7075	7.233e-103	340.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,4ESCV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, DeoR family	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR21617310_k127_25435_7	1122223.KB890701_gene2332	2.721e-105	354.0	COG0524@1|root,COG0524@2|Bacteria,1WKDK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR21617310_k127_25435_3	42256.RradSPS_3033	5.766e-139	457.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR21617310_k127_25435_1	926550.CLDAP_26850	3.471e-162	525.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR21617310_k127_25435_2	525904.Tter_2056	1.63e-154	495.0	COG1063@1|root,COG1063@2|Bacteria,2NPFX@2323|unclassified Bacteria	2|Bacteria	E	Glucose dehydrogenase C-terminus	gutB_1	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_25435_4	1206720.BAFQ01000118_gene2877	6.816e-120	411.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4FXHQ@85025|Nocardiaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_25435_6	1449353.JQMQ01000005_gene722	4.478e-111	375.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,2NIE9@228398|Streptacidiphilus	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10229	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	BPD_transp_1
SRR21617310_k127_25435_5	882083.SacmaDRAFT_4650	6.263e-117	385.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4DZMV@85010|Pseudonocardiales	201174|Actinobacteria	G	Permease component of ABC-type sugar transporter	smoF	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR21617310_k127_25435_0	234621.RER_36870	6.062e-168	543.0	COG1653@1|root,COG1653@2|Bacteria,2GNI2@201174|Actinobacteria,4FWAP@85025|Nocardiaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	smoE	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1
SRR21617310_k127_25435_9	1463879.JOHP01000072_gene3040	5.764e-89	304.0	COG2390@1|root,COG2390@2|Bacteria,2GMIM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K11531	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sugar-bind
SRR21617310_k127_2545947_2	1079986.JH164858_gene7644	4.629e-94	322.0	COG1752@1|root,COG1752@2|Bacteria,2I9XW@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR21617310_k127_2545947_5	512565.AMIS_5790	2.887e-52	189.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4DA1M@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0234 family	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR21617310_k127_2545947_6	1120950.KB892742_gene3001	4.293e-38	148.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4DNNW@85009|Propionibacteriales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
SRR21617310_k127_2545947_8	113395.AXAI01000006_gene1590	2.181e-20	95.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,3JRSI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR21617310_k127_2545947_7	1283283.ATXA01000035_gene2372	5.79e-35	137.0	COG3795@1|root,COG3795@2|Bacteria,2IQKK@201174|Actinobacteria,4ET8I@85013|Frankiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_2545947_0	35754.JNYJ01000008_gene3437	1.316e-162	527.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DB1I@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2545947_3	1121272.KB903250_gene3030	2.126e-93	316.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4DATY@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR21617310_k127_2545947_1	479433.Caci_6164	2.18e-106	353.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_2545947_4	1120950.KB892748_gene3207	3.399e-78	278.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DQIN@85009|Propionibacteriales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR21617310_k127_2545947_9	101510.RHA1_ro05305	3.989e-19	92.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	tesC	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0047617,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2
SRR21617310_k127_2545947_10	1206725.BAFU01000053_gene1700	0.000369	46.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4FUIY@85025|Nocardiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR21617310_k127_2552029_4	222534.KB893766_gene2938	3.518e-21	93.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_2552029_2	1120950.KB892746_gene3381	6.164e-45	167.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DU57@85009|Propionibacteriales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_2552029_3	1463901.JOIY01000086_gene1615	4.463e-25	117.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_2552029_1	1120950.KB892779_gene923	1.145e-131	424.0	COG2227@1|root,COG2227@2|Bacteria,2HY72@201174|Actinobacteria,4DT5Y@85009|Propionibacteriales	201174|Actinobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_2552029_6	350058.Mvan_5179	0.0002972	50.0	2956B@1|root,2ZSIU@2|Bacteria,2ISPI@201174|Actinobacteria,23B2N@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2552029_0	1287116.X734_09800	2.616e-179	572.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR21617310_k127_2552029_5	710111.FraQA3DRAFT_3875	3.855e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR21617310_k127_2557494_3	321955.AAGP01000002_gene3107	4.877e-16	81.0	COG1752@1|root,COG1752@2|Bacteria,2IA6V@201174|Actinobacteria,4F9WM@85019|Brevibacteriaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR21617310_k127_2557494_1	1288079.AUKN01000002_gene5483	3.204e-24	118.0	2DU8F@1|root,33PCG@2|Bacteria,2INGI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2557494_0	479432.Sros_6459	1.317e-32	141.0	2DU8F@1|root,33PCG@2|Bacteria,2INGI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2557494_5	479432.Sros_7814	8.8e-06	57.0	2BC3Y@1|root,325NS@2|Bacteria,2HAWG@201174|Actinobacteria,4EQIH@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2557494_4	1288079.AUKN01000002_gene5482	5.285e-09	66.0	294XH@1|root,2ZSAG@2|Bacteria,2IQ7X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2557494_2	710111.FraQA3DRAFT_0422	4.493e-23	102.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EV7C@85013|Frankiales	201174|Actinobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR21617310_k127_2566720_4	1144312.PMI09_04985	1.724e-18	93.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,SAM_1,SAM_2,TPR_12,TPR_4
SRR21617310_k127_2566720_0	1463909.KL585951_gene2031	1.654e-109	376.0	2C33A@1|root,33RI0@2|Bacteria,2H36M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2566720_3	525903.Taci_1493	6.128e-21	96.0	COG0613@1|root,COG1196@1|root,COG0613@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	3.1.3.97	ko:K07053,ko:K18491	ko04550,map04550	-	R00188,R11188	RC00078	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_21,AAA_23,PHP,PHP_C
SRR21617310_k127_2566720_1	96561.Dole_0791	7.049e-61	223.0	COG1237@1|root,COG1237@2|Bacteria,1RIH8@1224|Proteobacteria,42SZM@68525|delta/epsilon subdivisions,2WPQF@28221|Deltaproteobacteria,2MK8C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR21617310_k127_2566720_2	596153.Alide_2874	1.705e-40	159.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VHKE@28216|Betaproteobacteria,4AAHB@80864|Comamonadaceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
SRR21617310_k127_2574756_10	1120934.KB894410_gene6920	7.451e-55	194.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4E5W6@85010|Pseudonocardiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2574756_18	485913.Krac_11802	1.385e-33	136.0	COG3832@1|root,COG3832@2|Bacteria,2G9IK@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_2574756_17	1122611.KB904010_gene6831	9.056e-36	151.0	COG1309@1|root,COG1309@2|Bacteria,2GNQ6@201174|Actinobacteria,4EGWR@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR21617310_k127_2574756_23	1352941.M877_24230	0.0005125	48.0	COG0142@1|root,COG0142@2|Bacteria,2I4X3@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR21617310_k127_2574756_5	68219.JNXI01000006_gene2150	5.844e-108	357.0	COG0142@1|root,COG0761@1|root,COG0142@2|Bacteria,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,polyprenyl_synt
SRR21617310_k127_2574756_6	66377.JOBH01000021_gene5701	1.762e-94	320.0	COG0673@1|root,COG0673@2|Bacteria,2IAW2@201174|Actinobacteria	201174|Actinobacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR21617310_k127_2574756_1	645465.ACUR01000612_gene3942	1.25e-227	727.0	COG0624@1|root,COG1082@1|root,COG0624@2|Bacteria,COG1082@2|Bacteria,2GNS2@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Peptidase_M20
SRR21617310_k127_2574756_2	105425.BBPL01000021_gene790	3.79e-140	471.0	COG2055@1|root,COG2055@2|Bacteria,2GN93@201174|Actinobacteria,2NK0E@228398|Streptacidiphilus	201174|Actinobacteria	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
SRR21617310_k127_2574756_3	1254432.SCE1572_24590	1.869e-116	391.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	gal	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.376,1.1.1.48	ko:K00035,ko:K13873	ko00052,ko00053,ko01100,map00052,map00053,map01100	-	R01094,R01097,R01757,R10787	RC00161,RC00187	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
SRR21617310_k127_2574756_0	67352.JODS01000002_gene1670	2.234e-235	739.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR21617310_k127_2574756_20	591159.ACEZ01000180_gene6328	6.066e-17	92.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2574756_7	1123322.KB904711_gene5369	3.315e-75	258.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2574756_16	1343740.M271_38005	4.481e-41	156.0	COG0318@1|root,COG0318@2|Bacteria,2I2UX@201174|Actinobacteria	201174|Actinobacteria	IQ	acyl-CoA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_2574756_19	208439.AJAP_12230	5.147e-20	95.0	COG0318@1|root,COG0318@2|Bacteria,2I2UX@201174|Actinobacteria,4DX80@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_2574756_4	1137269.AZWL01000007_gene4304	1.266e-112	373.0	COG0318@1|root,COG0318@2|Bacteria,2I2UX@201174|Actinobacteria	201174|Actinobacteria	IQ	acyl-CoA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_2574756_14	1343740.M271_38000	4.279e-50	193.0	28PHV@1|root,2ZC86@2|Bacteria,2IEHK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2574756_8	1123322.KB904711_gene5371	1.09e-59	224.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR21617310_k127_2574756_11	33876.JNXY01000017_gene7158	1.894e-52	192.0	COG1232@1|root,COG1232@2|Bacteria,2HU4W@201174|Actinobacteria,4DB7C@85008|Micromonosporales	201174|Actinobacteria	H	amine oxidase	hemY	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR21617310_k127_2574756_22	1394178.AWOO02000046_gene6472	0.0001808	48.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4EFHW@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR21617310_k127_2574756_15	1121272.KB903290_gene4665	3.469e-41	156.0	COG4978@1|root,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,4DGGS@85008|Micromonosporales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
SRR21617310_k127_2574756_12	40571.JOEA01000005_gene4301	1.036e-51	194.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DZ9D@85010|Pseudonocardiales	2|Bacteria	E	ABC-type polar amino acid transport system, ATPase component	tupC	-	3.6.3.55	ko:K02065,ko:K02068,ko:K02071,ko:K05773,ko:K06857	ko02010,map02010	M00186,M00210,M00211,M00238,M00669,M00670	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.24,3.A.1.27,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
SRR21617310_k127_2574756_21	1190603.AJYD01000034_gene1992	1.272e-16	81.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,1RMG5@1236|Gammaproteobacteria,1Y24A@135623|Vibrionales	135623|Vibrionales	ET	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR21617310_k127_2574756_9	40571.JOEA01000005_gene4302	6.538e-59	211.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	glnH	-	-	ko:K02030,ko:K10039	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR21617310_k127_2574756_13	40571.JOEA01000005_gene4303	1.655e-50	186.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	glnM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR21617310_k127_2585667_0	479431.Namu_1909	1.179e-189	613.0	COG3299@1|root,COG3299@2|Bacteria,2GM5C@201174|Actinobacteria,4EST9@85013|Frankiales	201174|Actinobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR21617310_k127_2585667_1	1463887.KL589970_gene4638	8.953e-11	62.0	COG3628@1|root,COG3628@2|Bacteria,2IFJ6@201174|Actinobacteria	201174|Actinobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR21617310_k127_2595514_3	1463887.KL589953_gene173	4.468e-173	556.0	COG0582@1|root,COG0582@2|Bacteria,2IAX3@201174|Actinobacteria	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_2595514_9	1116232.AHBF01000164_gene5909	1.436e-22	108.0	COG0582@1|root,COG0582@2|Bacteria,2I9IX@201174|Actinobacteria	201174|Actinobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_2595514_0	1463855.JOHV01000028_gene1222	5.69e-268	845.0	COG0582@1|root,COG0582@2|Bacteria,2I9IX@201174|Actinobacteria	201174|Actinobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_2595514_7	1463855.JOHV01000028_gene1221	3.036e-46	173.0	2DUGZ@1|root,33QKJ@2|Bacteria,2IACF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2595514_1	1386089.N865_16085	1.292e-229	722.0	COG0477@1|root,COG2814@2|Bacteria,2I3MJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRR21617310_k127_2595514_2	543632.JOJL01000009_gene6052	1.732e-193	606.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DCID@85008|Micromonosporales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_2595514_5	994479.GL877879_gene5182	3.151e-64	230.0	2ECZS@1|root,336WS@2|Bacteria,2HCMY@201174|Actinobacteria,4DXZ7@85010|Pseudonocardiales	201174|Actinobacteria	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
SRR21617310_k127_2595514_6	994479.GL877879_gene5182	8.301e-54	200.0	2ECZS@1|root,336WS@2|Bacteria,2HCMY@201174|Actinobacteria,4DXZ7@85010|Pseudonocardiales	201174|Actinobacteria	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
SRR21617310_k127_2595514_8	1463820.JOGW01000002_gene6384	2.908e-34	148.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria	201174|Actinobacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR21617310_k127_2595514_11	1906.SFRA_07640	0.000316	44.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_2595514_4	66373.JOFQ01000006_gene2885	4.507e-150	480.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_2602618_2	857293.CAAU_2054	8.807e-15	78.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,36NYT@31979|Clostridiaceae	186801|Clostridia	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR21617310_k127_2602618_4	1033736.CAHK01000007_gene2315	6.235e-05	51.0	COG4995@1|root,COG4995@2|Bacteria,2I8HZ@201174|Actinobacteria,4FAQ3@85019|Brevibacteriaceae	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR21617310_k127_2602618_0	383372.Rcas_3076	1.251e-46	189.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SRR21617310_k127_2602618_3	457429.ABJI02000446_gene5397	5.248e-09	63.0	COG0247@1|root,COG0247@2|Bacteria,2H9RN@201174|Actinobacteria	201174|Actinobacteria	C	Glycerol-3-phosphate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR21617310_k127_2602618_1	1306174.JODP01000006_gene3075	2.051e-36	148.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,2GKUC@201174|Actinobacteria	201174|Actinobacteria	KT	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,PAS,PAS_4,SpoIIE
SRR21617310_k127_2610663_3	1229780.BN381_450012	4.597e-24	105.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
SRR21617310_k127_2610663_0	1229780.BN381_450011	6.641e-120	390.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR21617310_k127_2610663_1	1313172.YM304_04020	1.373e-59	220.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR21617310_k127_2610663_2	1229780.BN381_450009	2.783e-49	184.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR21617310_k127_2610663_4	1313172.YM304_04040	3.294e-16	91.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR21617310_k127_2610663_5	1229780.BN381_450007	2.516e-06	58.0	2FE68@1|root,34663@2|Bacteria,2H83B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_263732_3	1120950.KB892785_gene247	3.898e-27	121.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,RmlD_sub_bind
SRR21617310_k127_263732_4	1122138.AQUZ01000017_gene6562	2.012e-22	101.0	2DWQF@1|root,341EX@2|Bacteria,2IJK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_263732_0	1088869.GMO_11200	5.032e-72	258.0	COG0702@1|root,COG0702@2|Bacteria,1N3GN@1224|Proteobacteria,2VEY0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR21617310_k127_263732_2	1229780.BN381_130375	6.522e-40	161.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,MMPL
SRR21617310_k127_263732_1	1229780.BN381_430003	9.996e-46	171.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2640928_4	449447.MAE_01490	4.988e-08	54.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_2640928_3	29306.JOBE01000087_gene3931	1.459e-12	74.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_2640928_5	1211815.CBYP010000014_gene3466	7.159e-07	52.0	COG4974@1|root,COG4974@2|Bacteria,2HTVG@201174|Actinobacteria,4EUVH@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR21617310_k127_2640928_2	309801.trd_A0437	1.012e-59	219.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi,27Z2V@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_2640928_1	1121091.AUMP01000006_gene4155	3.738e-63	226.0	COG1028@1|root,COG1028@2|Bacteria,1V0TV@1239|Firmicutes,4HF8Q@91061|Bacilli	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_2640928_0	373994.Riv7116_4309	5.839e-86	297.0	COG0809@1|root,COG0809@2|Bacteria,1G02D@1117|Cyanobacteria,1HJ1X@1161|Nostocales	2|Bacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR21617310_k127_2643269_9	1120950.KB892790_gene2056	3.436e-31	134.0	COG0582@1|root,COG0582@2|Bacteria,2I9QS@201174|Actinobacteria,4DTV4@85009|Propionibacteriales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR21617310_k127_2643269_8	1429046.RR21198_0406	8.204e-36	141.0	2BB91@1|root,324RQ@2|Bacteria,2H9PI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2643269_0	1394178.AWOO02000005_gene3619	3.207e-184	593.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4EGVU@85012|Streptosporangiales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR21617310_k127_2643269_11	1068978.AMETH_4861	7.939e-28	117.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4E63H@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR21617310_k127_2643269_1	58344.JOEL01000029_gene2945	1.246e-158	522.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria	201174|Actinobacteria	GT	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR21617310_k127_2643269_2	436229.JOEH01000015_gene5947	1.298e-109	369.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,2NIC2@228398|Streptacidiphilus	201174|Actinobacteria	G	pfkB family carbohydrate kinase	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR21617310_k127_2643269_3	512565.AMIS_61170	3.266e-104	344.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,4D9FI@85008|Micromonosporales	201174|Actinobacteria	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR21617310_k127_2643269_4	391037.Sare_0337	8.777e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4D9JD@85008|Micromonosporales	201174|Actinobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR21617310_k127_2643269_13	1313172.YM304_37920	4.608e-10	65.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR21617310_k127_2643269_14	35754.JNYJ01000042_gene1339	1.408e-09	69.0	29WD1@1|root,30HYQ@2|Bacteria,2HUWM@201174|Actinobacteria,4DG8B@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
SRR21617310_k127_2643269_7	931627.MycrhDRAFT_0366	8.406e-37	152.0	COG0404@1|root,COG0404@2|Bacteria,2I4ER@201174|Actinobacteria,233N2@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR21617310_k127_2643269_10	1050202.KB913024_gene3694	2.905e-30	127.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria,408Z0@622450|Actinopolysporales	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2643269_12	983917.RGE_45010	3.478e-20	97.0	COG0745@1|root,COG0745@2|Bacteria,1N3FI@1224|Proteobacteria,2VU5F@28216|Betaproteobacteria,1KMA5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR21617310_k127_2643269_6	292459.STH2690	6.545e-49	189.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS
SRR21617310_k127_2643269_5	208444.JNYY01000006_gene7413	1.277e-52	195.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DYR1@85010|Pseudonocardiales	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR21617310_k127_2651170_3	521674.Plim_2104	2.741e-14	79.0	COG0863@1|root,COG0863@2|Bacteria,2IZ0F@203682|Planctomycetes	203682|Planctomycetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2651170_1	994479.GL877879_gene5880	3.188e-85	291.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4E084@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_2651170_4	255470.cbdbB42	3.609e-07	56.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi,34DDP@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR21617310_k127_2651170_5	100226.SCO7821	1.277e-06	56.0	2DDN7@1|root,2ZIN3@2|Bacteria,2IPRD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2651170_0	1449976.KALB_3688	1.092e-132	429.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4DZPN@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR21617310_k127_2651170_6	1121272.KB903261_gene5953	8.761e-05	51.0	COG2020@1|root,COG2020@2|Bacteria,2GTDR@201174|Actinobacteria,4DM6V@85008|Micromonosporales	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR21617310_k127_2651170_2	1123023.JIAI01000022_gene2306	1.506e-55	197.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_2653308_6	1121468.AUBR01000045_gene1801	4.906e-13	74.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR21617310_k127_2653308_4	1121468.AUBR01000045_gene1802	1.202e-100	343.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR21617310_k127_2653308_0	266117.Rxyl_0583	1.505e-261	816.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR21617310_k127_2653308_1	266117.Rxyl_0576	6.926e-164	530.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4CPAC@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM phenylalanine histidine ammonia-lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR21617310_k127_2653308_5	656024.FsymDg_4038	4.757e-57	212.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4ESMJ@85013|Frankiales	201174|Actinobacteria	G	phosphoglycerate mutase	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR21617310_k127_2653308_2	469371.Tbis_2965	1.974e-162	534.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DXMZ@85010|Pseudonocardiales	201174|Actinobacteria	L	helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR21617310_k127_2653308_3	390989.JOEG01000011_gene118	4.651e-136	449.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4DBRE@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR21617310_k127_265363_4	1122182.KB903838_gene4190	1.593e-12	74.0	COG2730@1|root,COG2755@1|root,COG3534@1|root,COG2730@2|Bacteria,COG2755@2|Bacteria,COG3534@2|Bacteria,2GK5H@201174|Actinobacteria,4D9TR@85008|Micromonosporales	201174|Actinobacteria	EGM	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,RicinB_lectin_2,Ricin_B_lectin,VCBS
SRR21617310_k127_265363_1	134676.ACPL_5646	1.095e-109	361.0	COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,4DCWK@85008|Micromonosporales	201174|Actinobacteria	S	MOSC domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR21617310_k127_265363_3	1108045.GORHZ_056_00020	1.275e-44	171.0	2C56A@1|root,323M1@2|Bacteria,2I5ZX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_265363_2	298653.Franean1_2887	5.433e-55	199.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_265363_0	318424.EU78_18140	1.682e-144	470.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,234FU@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_2653745_4	68170.KL590558_gene5400	9.867e-38	146.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DYJ3@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_2653745_3	1123023.JIAI01000022_gene2306	5.804e-49	180.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_2653745_6	653045.Strvi_4670	4.116e-30	127.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	DUF4376,HTH_21,HTH_Tnp_1
SRR21617310_k127_2653745_8	1894.JOER01000240_gene3685	1.084e-12	76.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
SRR21617310_k127_2653745_1	1206732.BAGD01000252_gene5857	1.042e-58	214.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4G8XI@85025|Nocardiaceae	201174|Actinobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
SRR21617310_k127_2653745_7	448385.sce6834	3.348e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,4395R@68525|delta/epsilon subdivisions,2X4C7@28221|Deltaproteobacteria,2YYQQ@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2653745_2	345341.KUTG_00914	4.354e-52	192.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4E4JZ@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_2653745_0	1068980.ARVW01000001_gene6519	3.46e-176	561.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4E278@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2653745_5	1120950.KB892781_gene428	1.097e-35	139.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,4DVT3@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_2658106_3	1869.MB27_19025	2.089e-42	160.0	COG1524@1|root,COG1524@2|Bacteria,2GK2R@201174|Actinobacteria,4DGUB@85008|Micromonosporales	201174|Actinobacteria	S	PglZ domain	pglZ	-	-	-	-	-	-	-	-	-	-	-	PglZ
SRR21617310_k127_2658106_1	356851.JOAN01000018_gene5693	7.859e-212	667.0	COG1474@1|root,COG1474@2|Bacteria,2HM4W@201174|Actinobacteria,4DGM5@85008|Micromonosporales	201174|Actinobacteria	LO	P-loop Domain of unknown function (DUF2791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2791
SRR21617310_k127_2658106_0	1123322.KB904666_gene3902	5e-324	1029.0	COG1201@1|root,COG1201@2|Bacteria,2GK56@201174|Actinobacteria	201174|Actinobacteria	L	dead DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR21617310_k127_2658106_2	882082.SaccyDRAFT_0622	3.023e-79	277.0	COG1002@1|root,COG1002@2|Bacteria,2GN30@201174|Actinobacteria,4DYTP@85010|Pseudonocardiales	201174|Actinobacteria	V	Type I restriction-modification system methyltransferase subunit	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR21617310_k127_2658106_4	396014.BF93_12160	1.059e-05	53.0	2AP32@1|root,31E4J@2|Bacteria,2HHQ1@201174|Actinobacteria,4FDXR@85020|Dermabacteraceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2674162_2	1179773.BN6_80630	2.86e-10	63.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4E6G1@85010|Pseudonocardiales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_2674162_1	653045.Strvi_5736	4.377e-13	74.0	2B18J@1|root,31TP0@2|Bacteria,2GSRF@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR21617310_k127_2674162_0	1403948.Q618_VCMC00001G0154	2.036e-29	126.0	2DMZU@1|root,32UNG@2|Bacteria,2HZJY@201174|Actinobacteria,4D7QE@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2675203_5	1157637.KB892090_gene6115	8.955e-116	396.0	COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRR21617310_k127_2675203_6	1463917.JODC01000007_gene7462	4.192e-82	278.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR21617310_k127_2675203_3	1463917.JODC01000007_gene7463	2.056e-124	411.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2675203_1	358823.DF19_10395	5.266e-227	713.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria	201174|Actinobacteria	F	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_2675203_0	351607.Acel_1043	4.728e-246	764.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4ESAX@85013|Frankiales	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR21617310_k127_2675203_7	1380390.JIAT01000011_gene2301	1.033e-42	168.0	COG1396@1|root,COG1396@2|Bacteria,2IC4C@201174|Actinobacteria,4CT6V@84995|Rubrobacteria	84995|Rubrobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2675203_4	479433.Caci_5332	7.917e-124	404.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
SRR21617310_k127_2675203_2	1894.JOER01000003_gene2809	2.229e-141	454.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR21617310_k127_267591_1	1267533.KB906737_gene1976	6.884e-82	283.0	COG1064@1|root,COG1064@2|Bacteria,3Y2QS@57723|Acidobacteria	57723|Acidobacteria	S	Zinc-binding dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_267591_0	861299.J421_6128	5.618e-93	328.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_267591_2	1214101.BN159_0442	1.944e-30	125.0	COG1359@1|root,COG1359@2|Bacteria,2GT9F@201174|Actinobacteria	201174|Actinobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_267591_3	351607.Acel_1816	2.477e-24	106.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4ET1U@85013|Frankiales	201174|Actinobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR21617310_k127_267766_10	446470.Snas_4592	4.162e-22	96.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4EY3S@85014|Glycomycetales	201174|Actinobacteria	HP	ThiF family	moeB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR21617310_k127_267766_8	1209984.BN978_07049	2.139e-33	138.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,2398P@1762|Mycobacteriaceae	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR21617310_k127_267766_6	1435356.Y013_02690	9.174e-49	179.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4FWYH@85025|Nocardiaceae	201174|Actinobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR21617310_k127_267766_1	351607.Acel_1138	2.664e-150	486.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4ERTT@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR21617310_k127_267766_3	1394178.AWOO02000020_gene7502	2.407e-105	347.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4EGEE@85012|Streptosporangiales	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR21617310_k127_267766_9	397278.JOJN01000004_gene1376	4.39e-25	115.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4DRMD@85009|Propionibacteriales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR21617310_k127_267766_5	1382356.JQMP01000003_gene2453	4.515e-74	268.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR21617310_k127_267766_0	1463879.JOHP01000031_gene5306	7.323e-236	738.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria	201174|Actinobacteria	O	assembly protein sufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR21617310_k127_267766_7	1123320.KB889679_gene2410	1.311e-39	159.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR21617310_k127_267766_2	1347086.CCBA010000003_gene3822	1.883e-127	424.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_267766_4	1347086.CCBA010000003_gene3821	2.409e-76	265.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_2678514_9	68170.KL590483_gene5557	7.18e-05	50.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E0CM@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_2678514_0	1463861.JNXE01000008_gene9413	9.267e-319	995.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR21617310_k127_2678514_4	1068980.ARVW01000001_gene3415	1.159e-68	246.0	COG0596@1|root,COG0596@2|Bacteria,2IFY9@201174|Actinobacteria,4E2WJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_2678514_8	1487923.DP73_09350	6.341e-12	76.0	COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,248JV@186801|Clostridia,260Z1@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR21617310_k127_2678514_2	1313172.YM304_18510	4.871e-113	385.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR21617310_k127_2678514_6	211114.JOEF01000036_gene1791	3.271e-38	148.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4E58S@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_2678514_1	749927.AMED_4702	1.581e-147	476.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DYZC@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2678514_7	390989.JOEG01000001_gene5067	2.68e-24	103.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4D9DP@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2678514_3	479434.Sthe_2971	1.084e-79	278.0	COG2267@1|root,COG2267@2|Bacteria,2G6MI@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_2678514_5	2002.JOEQ01000011_gene3965	6.875e-60	209.0	COG1959@1|root,COG1959@2|Bacteria,2IFDS@201174|Actinobacteria,4EPP5@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR21617310_k127_2678975_0	656024.FsymDg_0896	4.332e-120	398.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4ERIC@85013|Frankiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR21617310_k127_2678975_2	1123024.AUII01000005_gene2215	6.181e-31	133.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DXKC@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2678975_3	1242864.D187_009829	7.896e-05	53.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR21617310_k127_2678975_1	219305.MCAG_00333	9.048e-96	323.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DA2K@85008|Micromonosporales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR21617310_k127_2681522_6	298655.KI912266_gene3382	2.07e-19	91.0	COG1296@1|root,COG1296@2|Bacteria,2IKHA@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR21617310_k127_2681522_1	1111479.AXAR01000012_gene1419	5.256e-107	368.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli	91061|Bacilli	Q	Multicopper	cotA	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_2681522_5	1394178.AWOO02000003_gene2756	3.03e-50	184.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria,4ENX2@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR21617310_k127_2681522_2	298655.KI912266_gene3807	8.973e-104	347.0	COG0454@1|root,COG5006@1|root,COG0456@2|Bacteria,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4EVV9@85013|Frankiales	201174|Actinobacteria	K	permease, DMT superfamily	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR21617310_k127_2681522_0	479432.Sros_5690	7.423e-160	525.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EHSR@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_2681522_4	269800.Tfu_0869	1.123e-55	208.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4EK8J@85012|Streptosporangiales	201174|Actinobacteria	P	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_2681522_3	1380390.JIAT01000009_gene1158	6.779e-59	208.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR21617310_k127_2683314_1	365528.KB891217_gene1452	4.003e-64	229.0	COG0438@1|root,COG0438@2|Bacteria,2IFDU@201174|Actinobacteria,4EWZI@85013|Frankiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
SRR21617310_k127_2683314_0	1089551.KE386572_gene1344	5.04e-86	299.0	COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria,2TUKG@28211|Alphaproteobacteria,4BQF7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR21617310_k127_2683314_2	67332.FM21_35280	1.314e-33	142.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR21617310_k127_269037_2	196162.Noca_4842	2.092e-130	423.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4DWSS@85009|Propionibacteriales	201174|Actinobacteria	I	PFAM coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR21617310_k127_269037_3	196162.Noca_4814	7.574e-102	342.0	COG1028@1|root,COG1028@2|Bacteria,2GP7P@201174|Actinobacteria,4DR0M@85009|Propionibacteriales	201174|Actinobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR21617310_k127_269037_5	196162.Noca_4826	6.871e-84	295.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100,1.3.1.28	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	M00083,M00572	R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_269037_1	710685.MycrhN_2935	8.543e-160	516.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,235W1@1762|Mycobacteriaceae	201174|Actinobacteria	S	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
SRR21617310_k127_269037_4	1089544.KB912942_gene3165	1.032e-101	338.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4E51E@85010|Pseudonocardiales	201174|Actinobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR21617310_k127_269037_0	196162.Noca_4823	8.172e-197	632.0	COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria,4DPRW@85009|Propionibacteriales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_30
SRR21617310_k127_269037_6	196162.Noca_4828	4.052e-67	233.0	COG2197@1|root,COG2197@2|Bacteria,2IHW1@201174|Actinobacteria	201174|Actinobacteria	KT	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,MEDS
SRR21617310_k127_269037_7	1254432.SCE1572_09945	2.314e-28	124.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR21617310_k127_269532_1	479432.Sros_0277	2.547e-54	198.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EHF5@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_269532_5	1122138.AQUZ01000025_gene2793	0.0005863	49.0	2DRIE@1|root,33BXS@2|Bacteria,2GYYF@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR21617310_k127_269532_4	590998.Celf_3178	2.044e-10	66.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F2SB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_269532_0	656024.FsymDg_0967	3.617e-55	205.0	COG1088@1|root,COG1088@2|Bacteria,2I5AS@201174|Actinobacteria,4ESGC@85013|Frankiales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR21617310_k127_269532_3	665952.HMPREF1015_00811	1.319e-19	95.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,1ZRQP@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	sipT	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR21617310_k127_269532_2	298655.KI912266_gene2059	7.974e-49	186.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4ESJ1@85013|Frankiales	201174|Actinobacteria	Q	Superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR21617310_k127_2695366_3	1382356.JQMP01000001_gene1147	1.803e-89	314.0	COG0683@1|root,COG0683@2|Bacteria,2G7TX@200795|Chloroflexi,27YY0@189775|Thermomicrobia	189775|Thermomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_2695366_16	443143.GM18_3810	4.152e-10	66.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR21617310_k127_2695366_12	1133850.SHJG_0589	1.251e-28	126.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2695366_7	296591.Bpro_2383	2.185e-61	216.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_2695366_0	1449347.JQLN01000001_gene533	2.17e-143	477.0	COG3227@1|root,COG4409@1|root,COG3227@2|Bacteria,COG4409@2|Bacteria,2GN94@201174|Actinobacteria	201174|Actinobacteria	G	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR21617310_k127_2695366_2	266117.Rxyl_0963	2.323e-106	364.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR21617310_k127_2695366_5	266117.Rxyl_0964	2.407e-88	306.0	COG1035@1|root,COG2878@1|root,COG1035@2|Bacteria,COG2878@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR21617310_k127_2695366_4	1382304.JNIL01000001_gene1030	1.75e-88	309.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR21617310_k127_2695366_6	644966.Tmar_0766	1.203e-70	257.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,24IHQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR21617310_k127_2695366_1	196162.Noca_1430	6.423e-131	430.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,4DNSX@85009|Propionibacteriales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR21617310_k127_2695366_14	323848.Nmul_A2249	5.135e-23	99.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,373H6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR21617310_k127_2695366_8	1449355.JQNR01000005_gene2685	6.967e-55	200.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria	201174|Actinobacteria	S	PFAM GPR1 FUN34 yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
SRR21617310_k127_2695366_11	1206744.BAGL01000047_gene802	1.155e-28	123.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4G1AK@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_2695366_13	269797.Mbar_A2293	4.721e-26	118.0	arCOG01662@1|root,arCOG01662@2157|Archaea,2XX49@28890|Euryarchaeota,2N9SA@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_2695366_10	1121468.AUBR01000019_gene2638	3.023e-37	160.0	COG0123@1|root,COG0123@2|Bacteria,1VX2J@1239|Firmicutes,251VB@186801|Clostridia	186801|Clostridia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR21617310_k127_2695366_9	335543.Sfum_3172	3.02e-50	183.0	COG3829@1|root,COG3829@2|Bacteria,1QVJM@1224|Proteobacteria,43CC9@68525|delta/epsilon subdivisions,2X7N5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
SRR21617310_k127_2695366_15	710111.FraQA3DRAFT_4770	3.04e-17	81.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4ESB0@85013|Frankiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR21617310_k127_2696988_0	1172180.KB911791_gene7571	2.612e-33	135.0	2F1JS@1|root,33UK6@2|Bacteria,2ICBZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2696988_3	208439.AJAP_28145	5.519e-07	57.0	2EJ63@1|root,33CXA@2|Bacteria,2GQMS@201174|Actinobacteria,4E7Q1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2696988_4	67267.JNXT01000013_gene164	3.818e-05	53.0	29GNW@1|root,303KJ@2|Bacteria,2GRJ8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2696988_1	1306990.BARG01000072_gene7756	6.621e-28	131.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,2H75F@201174|Actinobacteria	201174|Actinobacteria	M	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2696988_2	463191.SSEG_09661	3.091e-25	117.0	COG4722@1|root,COG4722@2|Bacteria,2I6G0@201174|Actinobacteria	201174|Actinobacteria	S	Phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_tail
SRR21617310_k127_2698489_3	436229.JOEH01000035_gene2591	3.316e-35	151.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,2NGJ0@228398|Streptacidiphilus	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_2698489_1	477641.MODMU_3367	1.674e-57	211.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4ESJ3@85013|Frankiales	201174|Actinobacteria	FG	PFAM Histidine triad (HIT) protein	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR21617310_k127_2698489_2	195250.CM001776_gene717	1.781e-56	214.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1GZWS@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR21617310_k127_2698489_0	562970.Btus_0195	2.385e-98	327.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,2785J@186823|Alicyclobacillaceae	91061|Bacilli	P	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR21617310_k127_2714668_4	1121272.KB903289_gene4244	8.258e-51	193.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4D9KI@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR21617310_k127_2714668_2	479432.Sros_4002	6.81e-56	201.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4EJ30@85012|Streptosporangiales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR21617310_k127_2714668_3	1121430.JMLG01000028_gene1458	1.842e-52	187.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,262I5@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR21617310_k127_2714668_1	28444.JODQ01000007_gene5157	1.547e-60	235.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4EGMA@85012|Streptosporangiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR21617310_k127_2714668_0	570268.ANBB01000003_gene539	5.271e-123	409.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4EFSZ@85012|Streptosporangiales	201174|Actinobacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR21617310_k127_2716634_1	253839.SSNG_07250	5.714e-66	248.0	COG4974@1|root,COG4974@2|Bacteria,2GNKJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2716634_2	298653.Franean1_3446	3.754e-29	132.0	COG3655@1|root,COG3655@2|Bacteria,2IQQJ@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
SRR21617310_k127_2716634_0	253839.SSNG_07248	1.147e-138	455.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_2716634_3	1906.SFRA_11340	1.024e-06	53.0	COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria	201174|Actinobacteria	NU	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR21617310_k127_2729459_1	1123023.JIAI01000004_gene8147	8.903e-125	409.0	COG0520@1|root,COG0520@2|Bacteria,2I4DJ@201174|Actinobacteria,4EDZU@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR21617310_k127_2729459_3	1123023.JIAI01000004_gene8148	5.748e-74	260.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4DZJY@85010|Pseudonocardiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR21617310_k127_2729459_2	446470.Snas_5625	4.213e-109	359.0	COG1802@1|root,COG1802@2|Bacteria,2IBSA@201174|Actinobacteria	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR21617310_k127_2729459_0	1380386.JIAW01000001_gene5080	3.626e-129	418.0	COG0010@1|root,COG0010@2|Bacteria,2HG7E@201174|Actinobacteria,23EGM@1762|Mycobacteriaceae	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR21617310_k127_2729459_4	28444.JODQ01000003_gene4949	1.126e-12	72.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria,4EMKT@85012|Streptosporangiales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR21617310_k127_2730594_9	1123023.JIAI01000001_gene6499	8.824e-83	282.0	COG0329@1|root,COG0329@2|Bacteria,2IM0E@201174|Actinobacteria	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR21617310_k127_2730594_0	67352.JODS01000004_gene6091	2.487e-149	517.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR21617310_k127_2730594_5	1463845.JOIG01000010_gene2126	1.637e-94	348.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR21617310_k127_2730594_16	1042163.BRLA_c015830	5.452e-41	161.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,274RD@186822|Paenibacillaceae	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR21617310_k127_2730594_15	1123393.KB891316_gene1398	1.368e-55	219.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1KRA0@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR21617310_k127_2730594_4	358823.DF19_41025	1.76e-103	351.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_2730594_11	1394178.AWOO02000067_gene217	6.16e-70	262.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4EGQB@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2730594_3	43759.JNWK01000068_gene4173	1.449e-105	358.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR21617310_k127_2730594_6	656024.FsymDg_0692	7.587e-91	312.0	COG0392@1|root,COG0392@2|Bacteria,2GZ8W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205,ko:K20468	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR21617310_k127_2730594_7	1120936.KB907225_gene2713	5.966e-89	301.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR21617310_k127_2730594_1	1033730.CAHG01000006_gene1051	3.638e-146	493.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DPAG@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR21617310_k127_2730594_8	1382306.JNIM01000001_gene732	1.321e-86	292.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2730594_14	370438.PTH_0451	1.034e-61	233.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,260PU@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_2730594_2	469383.Cwoe_4903	2.668e-129	422.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CS29@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR21617310_k127_2730594_10	1380390.JIAT01000011_gene2751	1.3e-72	270.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CRYP@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR21617310_k127_2730594_12	1184609.KILIM_089_00130	5.555e-69	249.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR21617310_k127_2730594_13	1047013.AQSP01000140_gene2513	5.414e-67	242.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR21617310_k127_2737659_19	675635.Psed_1166	1.132e-06	60.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR21617310_k127_2737659_1	1283299.AUKG01000001_gene2437	3.588e-164	557.0	COG3899@1|root,COG3899@2|Bacteria,2HFRA@201174|Actinobacteria,4CR76@84995|Rubrobacteria	84995|Rubrobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR21617310_k127_2737659_6	296591.Bpro_1369	7.953e-102	343.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VJHX@28216|Betaproteobacteria,4ACRX@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
SRR21617310_k127_2737659_7	1123023.JIAI01000008_gene1488	2.893e-87	291.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4E3C2@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR21617310_k127_2737659_8	105422.BBPM01000014_gene3231	4.724e-75	271.0	COG1668@1|root,COG1668@2|Bacteria,2GQE9@201174|Actinobacteria,2NKHU@228398|Streptacidiphilus	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR21617310_k127_2737659_4	105422.BBPM01000014_gene3232	1.109e-125	411.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,2NKKH@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2737659_15	1306406.ASHX01000001_gene41	9.297e-37	146.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR21617310_k127_2737659_5	68223.JNZY01000010_gene1889	5.107e-104	344.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR21617310_k127_2737659_9	1329516.JPST01000056_gene867	1.731e-73	255.0	COG3510@1|root,COG3510@2|Bacteria,1V88X@1239|Firmicutes,4HK2A@91061|Bacilli	91061|Bacilli	V	Cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	CmcI
SRR21617310_k127_2737659_17	1267535.KB906767_gene5400	3.725e-08	57.0	2DW90@1|root,33Z49@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2737659_11	1306174.JODP01000007_gene2308	1.272e-70	240.0	COG3826@1|root,COG3826@2|Bacteria,2GK65@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K09990	-	-	-	-	ko00000	-	-	-	Oxygenase-NA
SRR21617310_k127_2737659_0	1449353.JQMQ01000005_gene338	9.314e-165	539.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,2NE76@228398|Streptacidiphilus	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
SRR21617310_k127_2737659_12	1382356.JQMP01000003_gene1614	7.286e-52	198.0	COG0061@1|root,COG0061@2|Bacteria,2G8JA@200795|Chloroflexi,27YB7@189775|Thermomicrobia	189775|Thermomicrobia	G	ATP-NAD kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
SRR21617310_k127_2737659_3	273068.TTE0688	2.386e-130	423.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,42HZK@68295|Thermoanaerobacterales	186801|Clostridia	C	1-deoxy-D-xylulose-5-phosphate synthase	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_2737659_2	562970.Btus_2388	7.73e-151	488.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,278RG@186823|Alicyclobacillaceae	91061|Bacilli	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_2737659_10	1003195.SCAT_4423	1.22e-71	259.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR21617310_k127_2737659_18	1121946.AUAX01000007_gene3011	1.546e-07	61.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4DBFR@85008|Micromonosporales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	prsR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR21617310_k127_2737659_13	1894.JOER01000023_gene7375	5.556e-47	177.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GXAS@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR21617310_k127_2737659_14	2002.JOEQ01000012_gene5606	2.12e-41	166.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4EQYN@85012|Streptosporangiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_2747037_1	1219045.BV98_003207	4.065e-76	267.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR21617310_k127_2747037_2	1121430.JMLG01000028_gene1476	4.713e-41	162.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR21617310_k127_2747037_0	570268.ANBB01000015_gene3749	4.722e-114	380.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR21617310_k127_2749748_3	408672.NBCG_02542	8.366e-54	190.0	arCOG08699@1|root,2Z9T7@2|Bacteria,2ISG8@201174|Actinobacteria,4DV8U@85009|Propionibacteriales	201174|Actinobacteria	C	Ammonia monooxygenase/methane monooxygenase, subunit C	-	-	-	ko:K10946	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	AmoC
SRR21617310_k127_2749748_0	408672.NBCG_02541	1.142e-119	389.0	28JPK@1|root,2Z9FM@2|Bacteria,2IMKK@201174|Actinobacteria,4DUFS@85009|Propionibacteriales	201174|Actinobacteria	C	Ammonia monooxygenase	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	AMO
SRR21617310_k127_2749748_1	408672.NBCG_02540	4.959e-102	348.0	28JC0@1|root,2Z96N@2|Bacteria,2IISZ@201174|Actinobacteria,4DU9E@85009|Propionibacteriales	201174|Actinobacteria	M	Monooxygenase subunit B protein	-	-	-	ko:K10945	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002	-	-	-	Monooxygenase_B
SRR21617310_k127_2749748_4	931627.MycrhDRAFT_3232	1.224e-21	104.0	2AUGT@1|root,31K50@2|Bacteria,2IKA2@201174|Actinobacteria,239M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2749748_2	1208323.B30_13114	9.135e-71	247.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_2754836_2	525904.Tter_2060	8.002e-34	146.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR21617310_k127_2754836_0	35754.JNYJ01000008_gene3209	7.081e-163	531.0	COG1073@1|root,COG1073@2|Bacteria,2I2V0@201174|Actinobacteria,4DCCQ@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR21617310_k127_2754836_1	543632.JOJL01000043_gene3802	2.627e-72	252.0	COG3315@1|root,COG3315@2|Bacteria,2I30H@201174|Actinobacteria	543632.JOJL01000043_gene3802|-	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2754836_4	298655.KI912266_gene4753	6.267e-06	57.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_2754836_3	345341.KUTG_09210	5.224e-06	55.0	2DRM0@1|root,33C8E@2|Bacteria,2ITBS@201174|Actinobacteria,4E7IG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2763276_18	562970.Btus_2665	4.396e-08	61.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,4IFRT@91061|Bacilli,27AAS@186823|Alicyclobacillaceae	91061|Bacilli	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR21617310_k127_2763276_13	1123258.AQXZ01000014_gene4924	3.805e-30	124.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4FW1B@85025|Nocardiaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_2763276_9	1120936.KB907218_gene3438	2.342e-44	184.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4EFQZ@85012|Streptosporangiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2763276_3	656024.FsymDg_4537	2.128e-86	308.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4ERF4@85013|Frankiales	201174|Actinobacteria	KLT	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR21617310_k127_2763276_6	1229780.BN381_100154	4.295e-71	260.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,3UW9J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_2763276_11	1121946.AUAX01000006_gene3373	2.428e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DD37@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2763276_19	867903.ThesuDRAFT_02140	7.064e-06	58.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR21617310_k127_2763276_17	266117.Rxyl_0788	4.918e-10	69.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,Peptidase_C39_2,TPR_16,TPR_2,TPR_4,TPR_8
SRR21617310_k127_2763276_1	525904.Tter_1226	4.719e-120	413.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR21617310_k127_2763276_10	1160137.KB907309_gene5990	2.964e-37	143.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4G24Y@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR21617310_k127_2763276_8	994479.GL877880_gene3972	2.018e-55	201.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4DXW4@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_2763276_0	479433.Caci_9047	1.702e-156	504.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria	201174|Actinobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	avtA	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR21617310_k127_2763276_5	1122611.KB903955_gene5582	3.154e-85	295.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4EFUD@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR21617310_k127_2763276_7	105425.BBPL01000053_gene5680	3.24e-65	231.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2I1PB@201174|Actinobacteria,2NMZI@228398|Streptacidiphilus	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2763276_15	1108045.GORHZ_056_00020	2.77e-12	72.0	2C56A@1|root,323M1@2|Bacteria,2I5ZX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2763276_2	351607.Acel_2154	4.523e-92	318.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4ERK5@85013|Frankiales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR21617310_k127_2763276_4	1229780.BN381_100161	8.057e-86	317.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,3UW6Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPase MipZ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR21617310_k127_2763276_12	1329250.WOSG25_011810	1.096e-32	137.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,4AX58@81850|Leuconostocaceae	91061|Bacilli	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR21617310_k127_2763276_14	1283300.ATXB01000001_gene2241	7.421e-14	76.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_2767045_0	749414.SBI_01051	5.486e-140	472.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
SRR21617310_k127_2767045_7	287986.DV20_26425	1.051e-21	110.0	COG0457@1|root,COG0457@2|Bacteria,2I538@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2767045_2	414996.IL38_03885	1.573e-67	254.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,407GH@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferases group 1	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_2767045_5	1122138.AQUZ01000019_gene8173	5.254e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_2767045_6	1155718.KB891902_gene1593	4.063e-25	114.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR21617310_k127_2767045_3	479435.Kfla_0703	4.006e-61	212.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4DV29@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2767045_4	1394178.AWOO02000075_gene1978	1.001e-58	219.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4EK3B@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2767045_1	28444.JODQ01000016_gene7152	4.226e-70	244.0	COG1028@1|root,COG1028@2|Bacteria,2GIVT@201174|Actinobacteria,4EISW@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR21617310_k127_2767045_9	512565.AMIS_31290	0.0007426	51.0	COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria,4DDRC@85008|Micromonosporales	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_2767045_8	675635.Psed_3248	9.243e-05	46.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E158@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_2768643_0	446470.Snas_4758	1.662e-61	228.0	COG3173@1|root,COG3173@2|Bacteria,2I165@201174|Actinobacteria,4F07B@85014|Glycomycetales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR21617310_k127_2768643_6	298653.Franean1_3420	9.937e-09	65.0	COG5659@1|root,COG5659@2|Bacteria,2H8EX@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_2768643_5	1123024.AUII01000004_gene1524	1.452e-10	69.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR21617310_k127_2768643_3	1089553.Tph_c28730	1.469e-24	108.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR21617310_k127_2768643_1	913865.DOT_0463	1.455e-43	176.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,2631B@186807|Peptococcaceae	186801|Clostridia	EG	DMT(Drug metabolite transporter) superfamily permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_2768643_4	247156.NFA_53170	1.567e-19	101.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4FU6N@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR21617310_k127_2776358_9	196162.Noca_1955	4.106e-95	319.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR21617310_k127_2776358_18	196162.Noca_1957	1.601e-34	149.0	COG2332@1|root,COG2332@2|Bacteria,2GTPS@201174|Actinobacteria	201174|Actinobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR21617310_k127_2776358_1	196162.Noca_1958	9.823e-239	758.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR21617310_k127_2776358_15	196162.Noca_1959	6.178e-44	182.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR21617310_k127_2776358_21	196162.Noca_1960	1.269e-18	98.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
SRR21617310_k127_2776358_19	196162.Noca_1961	4.99e-27	123.0	COG0457@1|root,COG0457@2|Bacteria	196162.Noca_1961|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2776358_13	1120950.KB892707_gene4764	9.073e-61	224.0	COG1309@1|root,COG1309@2|Bacteria,2IP3P@201174|Actinobacteria,4DSN9@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_2776358_6	1121406.JAEX01000007_gene2379	9.623e-126	421.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2MGAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR21617310_k127_2776358_2	298654.FraEuI1c_5768	4.187e-185	597.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR21617310_k127_2776358_3	1394178.AWOO02000094_gene8044	1.499e-182	579.0	COG1653@1|root,COG1653@2|Bacteria,2I0XV@201174|Actinobacteria,4EGPQ@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_2776358_5	479432.Sros_7938	1.28e-136	441.0	COG1175@1|root,COG1175@2|Bacteria,2GJWM@201174|Actinobacteria,4EHXB@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR21617310_k127_2776358_7	479432.Sros_7937	4.064e-122	413.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4EHJU@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR21617310_k127_2776358_8	105420.BBPO01000011_gene1963	4.519e-106	351.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NHNG@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2776358_14	1089544.KB912942_gene1686	4.26e-53	199.0	COG0842@1|root,COG0842@2|Bacteria,2H2PR@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_2776358_12	711393.AYRX01000083_gene4764	8.285e-64	232.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR21617310_k127_2776358_0	1394178.AWOO02000031_gene4791	2.503e-280	878.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4EFWP@85012|Streptosporangiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_2776358_16	1120949.KB903294_gene4302	1.247e-42	160.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N,Polyketide_cyc2,adh_short
SRR21617310_k127_2776358_11	1394178.AWOO02000021_gene7351	2.411e-73	265.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria,4EFHA@85012|Streptosporangiales	201174|Actinobacteria	PQ	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR21617310_k127_2776358_20	1206731.BAGB01000054_gene3704	3.753e-22	106.0	COG1846@1|root,COG1846@2|Bacteria,2GQ94@201174|Actinobacteria,4G304@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR21617310_k127_2776358_4	1120949.KB903294_gene3987	9.038e-161	524.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR21617310_k127_2776358_10	2074.JNYD01000015_gene4488	1.81e-73	254.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4E2MZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_2776358_23	1125971.ASJB01000064_gene6315	9.73e-06	53.0	COG1506@1|root,COG1680@1|root,COG1506@2|Bacteria,COG1680@2|Bacteria,2GMMM@201174|Actinobacteria,4DYU4@85010|Pseudonocardiales	201174|Actinobacteria	EV	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,PD40,Peptidase_S9
SRR21617310_k127_2776358_17	1157637.KB892124_gene779	6.129e-38	148.0	COG4420@1|root,COG4420@2|Bacteria,2INCC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR21617310_k127_277681_0	1137269.AZWL01000028_gene2845	2.901e-83	284.0	COG0343@1|root,COG0343@2|Bacteria,2I9KU@201174|Actinobacteria	201174|Actinobacteria	J	queuine tRNA-ribosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_277681_1	266940.Krad_4383	2.986e-47	177.0	COG1738@1|root,COG1738@2|Bacteria,2IGCP@201174|Actinobacteria	201174|Actinobacteria	S	Putative vitamin uptake transporter	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR21617310_k127_2780057_2	471857.Svir_13500	6.094e-63	218.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4E1WB@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR21617310_k127_2780057_6	2002.JOEQ01000009_gene6490	3.988e-10	61.0	COG0582@1|root,COG0582@2|Bacteria,2I8XR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_2780057_4	2002.JOEQ01000009_gene6490	1.53e-33	134.0	COG0582@1|root,COG0582@2|Bacteria,2I8XR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_2780057_5	1382356.JQMP01000003_gene1584	1.028e-22	111.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR21617310_k127_2780057_3	1047013.AQSP01000100_gene587	1.259e-54	207.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2780057_1	483219.LILAB_22120	8.753e-209	662.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR21617310_k127_2780057_0	215803.DB30_3757	1.105e-221	698.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria,2YUBS@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR21617310_k127_2785434_15	1476876.JOJO01000024_gene1724	1.726e-16	82.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
SRR21617310_k127_2785434_3	1116369.KB890024_gene228	1.431e-140	455.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2U1HV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_2785434_6	366394.Smed_5064	1.036e-115	396.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,4B8UD@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_2785434_5	1116369.KB890024_gene230	5.557e-118	389.0	COG1173@1|root,COG1173@2|Bacteria,1MXGS@1224|Proteobacteria,2TTQ7@28211|Alphaproteobacteria,43NEV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR21617310_k127_2785434_7	1116369.KB890024_gene231	7.394e-112	369.0	COG0601@1|root,COG0601@2|Bacteria,1MW3U@1224|Proteobacteria,2TUR2@28211|Alphaproteobacteria,43P07@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR21617310_k127_2785434_2	1116369.KB890024_gene232	3.921e-173	557.0	COG0747@1|root,COG0747@2|Bacteria,1PHCN@1224|Proteobacteria,2TV1F@28211|Alphaproteobacteria,43PJE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
SRR21617310_k127_2785434_0	1408254.T458_24000	7.232e-217	706.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HE2A@91061|Bacilli,275SQ@186822|Paenibacillaceae	91061|Bacilli	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2785434_11	1206729.BAFZ01000001_gene34	2.477e-67	236.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4FWH1@85025|Nocardiaceae	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3,1.5.99.4	ko:K03518,ko:K19819	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_2785434_10	479434.Sthe_2813	5.666e-79	289.0	COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_2785434_4	1089553.Tph_c23930	1.489e-119	401.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR21617310_k127_2785434_1	1382306.JNIM01000001_gene1832	7.89e-210	677.0	COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_2785434_14	1157490.EL26_12195	3.22e-44	186.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,2793S@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR21617310_k127_2785434_12	211165.AJLN01000040_gene6453	2.606e-50	185.0	COG1846@1|root,COG1846@2|Bacteria,1G5RS@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR21617310_k127_2785434_9	1380355.JNIJ01000031_gene3513	4.744e-110	366.0	COG2141@1|root,COG2141@2|Bacteria,1QGWA@1224|Proteobacteria,2UNBA@28211|Alphaproteobacteria,3K5C8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR21617310_k127_2785434_13	1382304.JNIL01000001_gene3039	3.105e-45	175.0	COG0329@1|root,COG0329@2|Bacteria,1TPVS@1239|Firmicutes,4HATJ@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR21617310_k127_2785434_8	479434.Sthe_2890	7.247e-111	369.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	MA20_04180	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR21617310_k127_2792866_0	1144275.COCOR_02357	9.798e-302	977.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR21617310_k127_2792866_4	909613.UO65_0526	4.672e-28	119.0	COG3251@1|root,COG3251@2|Bacteria,2GQIK@201174|Actinobacteria,4ECDX@85010|Pseudonocardiales	201174|Actinobacteria	S	MbtH-like protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
SRR21617310_k127_2792866_1	644283.Micau_3705	1.617e-272	859.0	COG0318@1|root,COG0318@2|Bacteria,2GJI9@201174|Actinobacteria,4D9K2@85008|Micromonosporales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2792866_3	644283.Micau_3706	4.66e-85	289.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4DB4J@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_2792866_2	644283.Micau_3707	2.721e-150	482.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4D8H1@85008|Micromonosporales	201174|Actinobacteria	V	Daunorubicin resistance abc transporter atpase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_2798709_0	457570.Nther_2188	5.788e-34	146.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_2799596_0	1169154.KB897793_gene885	6.469e-60	210.0	COG0346@1|root,COG0346@2|Bacteria,2IFCU@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2799596_1	1120949.KB903357_gene4802	3.594e-57	220.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4D8Q0@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR21617310_k127_2804148_1	1454010.JEOE01000001_gene594	2.374e-41	166.0	2EJ40@1|root,33CVA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2804148_0	1125863.JAFN01000001_gene2057	1.228e-204	650.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_2810308_1	67332.FM21_17290	2.235e-33	135.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_2810308_2	67332.FM21_17295	1.019e-32	140.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR21617310_k127_2810308_3	429009.Adeg_0012	0.0005888	47.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42HQ7@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_2810308_0	981369.JQMJ01000002_gene4	1.508e-58	205.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,2NIEB@228398|Streptacidiphilus	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_2811698_3	404589.Anae109_1654	5.019e-13	72.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR21617310_k127_2811698_2	1183438.GKIL_0709	3.243e-17	87.0	COG2764@1|root,COG2764@2|Bacteria,1G8SR@1117|Cyanobacteria	1117|Cyanobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_2811698_0	356851.JOAN01000020_gene4011	9.255e-92	307.0	COG4122@1|root,COG4122@2|Bacteria,2IARG@201174|Actinobacteria,4DKAV@85008|Micromonosporales	201174|Actinobacteria	H	Macrocin-O-methyltransferase (TylF)	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0030769,GO:0032259,GO:0044237,GO:0044249	2.1.1.101,2.1.1.307	ko:K05303,ko:K15996,ko:K19569	ko00522,ko01057,ko01130,map00522,map01057,map01130	M00773,M00784	R02858,R10958	RC00003,RC00466	ko00000,ko00001,ko00002,ko01000	-	-	-	TylF
SRR21617310_k127_2811698_1	485913.Krac_4690	1.413e-71	256.0	COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2818794_4	1169161.KB897717_gene2837	1.31e-44	166.0	COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria	201174|Actinobacteria	NU	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR21617310_k127_2818794_9	285535.JOEY01000086_gene7183	0.0004566	43.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria	201174|Actinobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR21617310_k127_2818794_3	345341.KUTG_03794	1.144e-51	188.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4DZJN@85010|Pseudonocardiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR21617310_k127_2818794_5	479432.Sros_4277	8.136e-39	158.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4EG49@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR21617310_k127_2818794_6	1122138.AQUZ01000106_gene4246	7.764e-11	73.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4DVWW@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_2818794_2	1122182.KB903839_gene1079	4.892e-52	197.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DBZU@85008|Micromonosporales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_2818794_0	471852.Tcur_3550	1.258e-79	278.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EHUT@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_2818794_1	324602.Caur_0822	5.899e-69	242.0	COG1136@1|root,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
SRR21617310_k127_2818794_8	1957.JODX01000006_gene3937	0.0001712	54.0	COG0577@1|root,COG0577@2|Bacteria,2I90E@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR21617310_k127_2818794_7	1283287.KB822575_gene61	7.963e-06	58.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DUD5@85009|Propionibacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_282015_3	324602.Caur_0205	1.755e-48	182.0	COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi,376KV@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR21617310_k127_282015_1	2074.JNYD01000026_gene693	3.702e-215	678.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4E9TY@85010|Pseudonocardiales	201174|Actinobacteria	J	Anticodon binding domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR21617310_k127_282015_0	525904.Tter_2842	1.671e-222	703.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	1.14.18.2	ko:K08080,ko:K14952	ko00520,ko05152,map00520,map05152	-	R01115,R01803	RC00157	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_3,Rieske
SRR21617310_k127_282015_4	469371.Tbis_2312	9.056e-48	180.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4DZFM@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-ribbon protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR21617310_k127_282015_5	1463825.JNXC01000036_gene3552	6.888e-45	168.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR21617310_k127_282015_8	408672.NBCG_02866	1.011e-23	112.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4DR8M@85009|Propionibacteriales	201174|Actinobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR21617310_k127_282015_9	345341.KUTG_04140	1.271e-13	83.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_282015_7	290397.Adeh_3692	4.887e-27	123.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR21617310_k127_282015_2	269800.Tfu_0970	1.165e-61	220.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4EHW3@85012|Streptosporangiales	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR21617310_k127_282015_6	1123065.ATWL01000016_gene1988	1.928e-39	162.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria	201174|Actinobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR21617310_k127_2820525_8	471852.Tcur_2041	2.96e-42	176.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4EQYY@85012|Streptosporangiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_2820525_7	1209984.BN978_04221	4.763e-44	165.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,23A9X@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR21617310_k127_2820525_5	710696.Intca_3035	7.922e-104	344.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4FF9V@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_2820525_4	33876.JNXY01000004_gene1454	6.629e-109	379.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DA7P@85008|Micromonosporales	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_2820525_1	710696.Intca_3037	2.7e-154	511.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_2820525_2	33876.JNXY01000004_gene1452	2.429e-135	436.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4DM3Q@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_2820525_0	710696.Intca_3039	5.839e-201	633.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_2820525_3	292459.STH1143	3.258e-120	407.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR21617310_k127_2820525_6	179408.Osc7112_0136	4.828e-55	214.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1H93G@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR21617310_k127_2820525_9	1380390.JIAT01000010_gene4370	2.925e-23	105.0	COG1409@1|root,COG1409@2|Bacteria,2GVVJ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR21617310_k127_282165_5	1313172.YM304_31150	4.335e-14	72.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase,SCP2
SRR21617310_k127_282165_6	1207055.C100_14550	1.499e-07	63.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2K1GW@204457|Sphingomonadales	204457|Sphingomonadales	T	Osmosensitive K channel	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR21617310_k127_282165_4	2074.JNYD01000003_gene3518	3.289e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DZ76@85010|Pseudonocardiales	201174|Actinobacteria	T	Member of the two-component regulatory system kdpD kdpE involved in the regulation of the kdp operon	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_282165_0	479434.Sthe_2502	7.192e-137	466.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_282165_2	1449353.JQMQ01000005_gene4041	3.431e-65	246.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,2NGAI@228398|Streptacidiphilus	201174|Actinobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR21617310_k127_282165_1	765420.OSCT_0418	4.28e-68	250.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_282165_3	1117379.BABA_14322	6.691e-21	92.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_2832828_1	324602.Caur_3769	2.053e-14	85.0	COG2152@1|root,COG3055@1|root,COG3266@1|root,COG5624@1|root,COG2152@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG5624@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR21617310_k127_2832828_0	1120950.KB892707_gene4643	1.254e-136	449.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNT3@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR21617310_k127_2837829_0	1306990.BARG01000120_gene10162	8.458e-42	155.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_2837829_3	1299327.I546_5948	8.055e-05	46.0	28NDD@1|root,2ZBG6@2|Bacteria,2H1UZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2837829_1	40571.JOEA01000021_gene6868	7.926e-22	105.0	2ECZS@1|root,336WS@2|Bacteria,2HCMY@201174|Actinobacteria,4DXZ7@85010|Pseudonocardiales	201174|Actinobacteria	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
SRR21617310_k127_2837829_2	861299.J421_1485	1.909e-06	56.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_1485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2837933_5	644283.Micau_6082	1.453e-09	63.0	2E9PN@1|root,30JG0@2|Bacteria,2HV2T@201174|Actinobacteria,4DGJM@85008|Micromonosporales	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2837933_3	1463856.JOHY01000035_gene1832	1.201e-25	117.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR21617310_k127_2837933_1	292459.STH2279	1.569e-116	390.0	COG3328@1|root,COG3328@2|Bacteria,1V116@1239|Firmicutes,24D8K@186801|Clostridia	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_2837933_4	1121468.AUBR01000001_gene448	1.236e-22	112.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42GQK@68295|Thermoanaerobacterales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_2837933_0	33876.JNXY01000039_gene6686	6.405e-153	492.0	28IDQ@1|root,2Z8FW@2|Bacteria,2ICD9@201174|Actinobacteria,4DH6U@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2837933_2	33876.JNXY01000039_gene6685	3.131e-34	131.0	2DMB2@1|root,32UGJ@2|Bacteria,2I1VY@201174|Actinobacteria,4DKEK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2845846_4	1352941.M877_21370	6.039e-142	461.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2845846_1	1120936.KB907211_gene405	1.406e-236	755.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4EFRT@85012|Streptosporangiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR21617310_k127_2845846_0	656024.FsymDg_2722	0.0	1178.0	COG2183@1|root,COG2183@2|Bacteria,2GKCI@201174|Actinobacteria,4ETVQ@85013|Frankiales	201174|Actinobacteria	K	SMART Resolvase RNase H domain protein fold	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR21617310_k127_2845846_8	1120936.KB907208_gene1211	6.569e-91	306.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR21617310_k127_2845846_2	1120950.KB892707_gene4783	3.031e-176	569.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria,4DS9D@85009|Propionibacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP_C
SRR21617310_k127_2845846_11	1223523.H340_11245	1.179e-73	253.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR21617310_k127_2845846_9	1394178.AWOO02000067_gene217	3.184e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4EGQB@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2845846_10	1394178.AWOO02000067_gene216	2.507e-76	265.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EFVQ@85012|Streptosporangiales	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR21617310_k127_2845846_6	1394178.AWOO02000067_gene215	1.008e-113	378.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4EGJE@85012|Streptosporangiales	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR21617310_k127_2845846_7	1246995.AFR_36790	1.352e-113	386.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4DBVE@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58,Ery_res_leader1
SRR21617310_k127_2845846_3	1283283.ATXA01000001_gene909	1.433e-146	472.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4ERGM@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR21617310_k127_2845846_14	1274524.BSONL12_12156	1.743e-10	74.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	ykvY	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR21617310_k127_2845846_5	1394178.AWOO02000021_gene7358	5.04e-123	408.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,4EID5@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR21617310_k127_2845846_12	317619.ANKN01000161_gene313	1.096e-33	134.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1MKDA@1212|Prochloraceae	1117|Cyanobacteria	T	Alternative locus ID	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2845846_13	1380394.JADL01000003_gene4756	7.255e-33	136.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria,2JUHF@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_2846040_7	1449353.JQMQ01000005_gene2157	1.848e-32	127.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,2NGUW@228398|Streptacidiphilus	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR21617310_k127_2846040_1	1120950.KB892745_gene2917	3.092e-113	374.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DMZ6@85009|Propionibacteriales	201174|Actinobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR21617310_k127_2846040_0	1146883.BLASA_3889	2.942e-234	737.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4ES55@85013|Frankiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase large subunit	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR21617310_k127_2846040_2	356851.JOAN01000030_gene5027	1.569e-109	364.0	COG1171@1|root,COG1171@2|Bacteria,2GKCC@201174|Actinobacteria,4D8JB@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_2846040_4	1463845.JOIG01000006_gene1166	6.682e-95	317.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_2846040_6	264732.Moth_1935	1.038e-62	241.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42F43@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
SRR21617310_k127_2846040_5	469371.Tbis_2846	3.485e-86	295.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR21617310_k127_2846040_3	479433.Caci_1298	1.737e-102	345.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR21617310_k127_2852032_26	477641.MODMU_4974	4.693e-10	61.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4ERZ2@85013|Frankiales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR21617310_k127_2852032_8	222534.KB893739_gene1390	3.988e-134	444.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4ERPF@85013|Frankiales	201174|Actinobacteria	C	geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR21617310_k127_2852032_22	1288083.AUKR01000012_gene572	2.702e-37	144.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR21617310_k127_2852032_15	222534.KB893739_gene1388	1.354e-83	287.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4ERM4@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR21617310_k127_2852032_18	390989.JOEG01000009_gene1089	6.733e-54	196.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4D9YC@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR21617310_k127_2852032_1	28042.GU90_05710	1.421e-180	587.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DZ6H@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR21617310_k127_2852032_20	656024.FsymDg_4003	1.725e-46	177.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4ESCP@85013|Frankiales	201174|Actinobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR21617310_k127_2852032_2	326424.FRAAL1037	4.094e-177	564.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4ERDU@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR21617310_k127_2852032_0	365528.KB891252_gene5635	3.606e-198	645.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4ES5W@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR21617310_k127_2852032_9	1121946.AUAX01000003_gene1714	1.425e-116	398.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4D8E0@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR21617310_k127_2852032_17	351607.Acel_0275	1.71e-59	233.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4ESDX@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR21617310_k127_2852032_21	656024.FsymDg_3998	2.675e-37	149.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4ESIY@85013|Frankiales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR21617310_k127_2852032_23	263358.VAB18032_06155	1.726e-35	148.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4DE4V@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR21617310_k127_2852032_3	1206730.BAGA01000079_gene1303	1.473e-172	563.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4FWHS@85025|Nocardiaceae	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR21617310_k127_2852032_6	1125863.JAFN01000001_gene2409	5.843e-143	473.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR21617310_k127_2852032_10	1048339.KB913029_gene2589	2.236e-109	374.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4ERCH@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR21617310_k127_2852032_13	656024.FsymDg_3993	1.046e-93	317.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4ERU8@85013|Frankiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR21617310_k127_2852032_14	66869.JNXG01000002_gene5813	5.574e-87	297.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria,4182R@629295|Streptomyces griseus group	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR21617310_k127_2852032_19	1394178.AWOO02000003_gene2834	8.218e-47	180.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria,4EIQ6@85012|Streptosporangiales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR21617310_k127_2852032_7	1120949.KB903319_gene9743	2.62e-139	456.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DACF@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR21617310_k127_2852032_12	35754.JNYJ01000004_gene6013	9.408e-103	358.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4DB5M@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR21617310_k127_2852032_16	1449353.JQMQ01000005_gene3554	6.131e-76	264.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,2NG5P@228398|Streptacidiphilus	201174|Actinobacteria	C	4Fe-4S dicluster domain	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR21617310_k127_2852032_24	1120936.KB907214_gene4546	6.466e-35	147.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4EIJM@85012|Streptosporangiales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR21617310_k127_2852032_25	1123322.KB904714_gene5327	1.938e-29	123.0	COG0713@1|root,COG0713@2|Bacteria,2IHNW@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR21617310_k127_2852032_5	562970.Btus_3223	5.994e-153	509.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,27873@186823|Alicyclobacillaceae	91061|Bacilli	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR21617310_k127_2852032_4	1122611.KB904001_gene8116	2.339e-157	512.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4EI1F@85012|Streptosporangiales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR21617310_k127_2852032_11	1313172.YM304_35550	1.646e-106	361.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR21617310_k127_2869062_1	591157.SSLG_00168	2.821e-82	282.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR21617310_k127_2869062_3	1123024.AUII01000026_gene2568	1.32e-60	219.0	COG4638@1|root,COG4638@2|Bacteria,2GP4B@201174|Actinobacteria,4E93H@85010|Pseudonocardiales	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRR21617310_k127_2869062_5	1395571.TMS3_0107645	4.903e-30	123.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RSEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRR21617310_k127_2869062_7	330084.JNYZ01000020_gene4714	9.495e-09	68.0	COG5517@1|root,COG5517@2|Bacteria,2IGU3@201174|Actinobacteria,4EDGR@85010|Pseudonocardiales	201174|Actinobacteria	Q	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Ring_hydroxyl_B
SRR21617310_k127_2869062_6	1048339.KB913029_gene2392	1.039e-09	66.0	COG5517@1|root,COG5517@2|Bacteria,2HCJB@201174|Actinobacteria,4ETKJ@85013|Frankiales	201174|Actinobacteria	Q	Ring hydroxylating beta subunit	-	-	1.14.12.10	ko:K05550	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ring_hydroxyl_B
SRR21617310_k127_2869062_0	1134413.ANNK01000091_gene77	1.244e-90	310.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes,4HDDV@91061|Bacilli,1ZEPT@1386|Bacillus	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR21617310_k127_2869062_4	1463857.JOFZ01000001_gene5441	1.298e-36	156.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR21617310_k127_2869062_2	1122915.AUGY01000020_gene6474	3.065e-81	292.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.1.69,4.1.2.17	ko:K01628,ko:K18256	ko00051,ko00624,ko01120,map00051,map00624,map01120	M00636	R01634,R02262	RC00569,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,UPF0066
SRR21617310_k127_2873584_4	570268.ANBB01000055_gene4873	3.333e-24	102.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4EK3Q@85012|Streptosporangiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_2873584_0	1869.MB27_23030	4.886e-266	837.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR21617310_k127_2873584_1	211114.JOEF01000006_gene2562	6.115e-218	687.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4DYCA@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_2873584_5	1079986.JH164860_gene7101	6.585e-20	96.0	COG3631@1|root,COG3631@2|Bacteria,2IFBE@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR21617310_k127_2873584_2	1157640.AQWO01000005_gene2020	3.479e-101	337.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_2873584_3	1206744.BAGL01000070_gene5104	1.179e-37	147.0	COG2259@1|root,31BQE@2|Bacteria,2GT4C@201174|Actinobacteria,4G1WU@85025|Nocardiaceae	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR21617310_k127_2875122_2	653045.Strvi_6073	1.559e-83	279.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhfe	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR21617310_k127_2875122_0	1172179.AUKV01000009_gene4529	5.433e-152	494.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR21617310_k127_2875122_1	298654.FraEuI1c_2442	5.816e-91	305.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR21617310_k127_2878760_5	880073.Calab_3338	7.4e-11	65.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
SRR21617310_k127_2878760_1	263358.VAB18032_22930	3.132e-71	246.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DB0D@85008|Micromonosporales	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR21617310_k127_2878760_2	222534.KB893750_gene4280	3.769e-65	234.0	COG1266@1|root,COG1266@2|Bacteria,2GK11@201174|Actinobacteria,4ESXA@85013|Frankiales	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR21617310_k127_2878760_0	1120949.KB903297_gene5433	3.85e-147	483.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,4DB1Y@85008|Micromonosporales	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR21617310_k127_2878760_3	644283.Micau_1683	3.346e-59	212.0	COG1309@1|root,COG1309@2|Bacteria,2GP3D@201174|Actinobacteria,4DD5T@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR21617310_k127_2878760_4	446470.Snas_1978	3.624e-32	127.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EZWJ@85014|Glycomycetales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR21617310_k127_2878874_5	1380390.JIAT01000009_gene554	3.207e-44	168.0	COG1396@1|root,COG1396@2|Bacteria,2GJXM@201174|Actinobacteria,4CT6J@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2878874_6	485913.Krac_4648	8.951e-17	87.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_2878874_4	1123023.JIAI01000001_gene6982	3.952e-60	212.0	COG5485@1|root,COG5485@2|Bacteria,2HPCK@201174|Actinobacteria,4E7Y5@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR21617310_k127_2878874_1	146922.JOFU01000062_gene89	6.416e-103	344.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_2878874_0	526225.Gobs_2584	2.014e-162	515.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR21617310_k127_2878874_8	469383.Cwoe_3066	8.005e-09	67.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR21617310_k127_2878874_3	749927.AMED_2717	5.691e-69	241.0	COG0500@1|root,COG2320@1|root,COG2226@2|Bacteria,COG2320@2|Bacteria,2ICDV@201174|Actinobacteria,4E3U7@85010|Pseudonocardiales	201174|Actinobacteria	Q	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB,Methyltransf_11
SRR21617310_k127_2878874_7	562970.Btus_0774	4.667e-12	70.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,278H7@186823|Alicyclobacillaceae	91061|Bacilli	M	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
SRR21617310_k127_2878874_2	287986.DV20_00140	8.472e-89	302.0	COG3315@1|root,COG3315@2|Bacteria,2GM4W@201174|Actinobacteria,4E4XE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	ko:K16038	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09856	RC00003,RC02842	ko00000,ko00001,ko01000	-	-	-	LCM,NUDIX
SRR21617310_k127_2891598_0	1380356.JNIK01000018_gene821	6.825e-96	327.0	COG0392@1|root,COG0392@2|Bacteria,2ICMJ@201174|Actinobacteria,4ETKK@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR21617310_k127_2891598_2	710685.MycrhN_2818	1.567e-41	163.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
SRR21617310_k127_2891598_1	1133849.O3I_018095	4.858e-82	292.0	COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4FXZC@85025|Nocardiaceae	201174|Actinobacteria	IT	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K07027,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011,ko02000	4.D.2	-	-	LPG_synthase_TM,PAP2
SRR21617310_k127_2891598_3	1386089.N865_05855	1.408e-23	101.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FI4Q@85021|Intrasporangiaceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_2895962_5	570268.ANBB01000004_gene135	1.63e-90	310.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR21617310_k127_2895962_4	1144275.COCOR_06476	3.814e-97	335.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR21617310_k127_2895962_7	1313172.YM304_20790	3.31e-84	295.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CMY2@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR21617310_k127_2895962_8	656024.FsymDg_3277	1.291e-83	299.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4ES7A@85013|Frankiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR21617310_k127_2895962_6	292459.STH2882	1.456e-84	301.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
SRR21617310_k127_2895962_2	1137271.AZUM01000013_gene4328	7.361e-114	380.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4DX7N@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR21617310_k127_2895962_12	351607.Acel_1258	7.038e-33	145.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4ESWE@85013|Frankiales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR21617310_k127_2895962_13	644966.Tmar_0539	3.896e-24	104.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR21617310_k127_2895962_3	867903.ThesuDRAFT_02026	6.996e-101	336.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR21617310_k127_2895962_1	298654.FraEuI1c_1718	5.608e-116	391.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4ES14@85013|Frankiales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR21617310_k127_2895962_14	219305.MCAG_01464	4.458e-20	102.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2895962_11	1380390.JIAT01000011_gene2542	7.043e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_2895962_0	1323361.JPOC01000002_gene4499	7.128e-153	509.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4G6DS@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_2895962_16	861299.J421_0709	7.091e-11	73.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	LOR
SRR21617310_k127_2895962_9	1532558.JL39_29110	9.445e-78	280.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,4B70K@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR21617310_k127_2895962_10	266940.Krad_1020	3.123e-64	245.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_2895962_15	1125863.JAFN01000001_gene2057	2.119e-16	82.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_291066_7	40571.JOEA01000005_gene4304	3.149e-36	145.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR21617310_k127_291066_1	1157637.KB892103_gene1633	3.292e-128	417.0	COG1670@1|root,COG1670@2|Bacteria,2I39Q@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_291066_6	1240349.ANGC01000047_gene4661	9.884e-57	204.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,4G0EJ@85025|Nocardiaceae	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR21617310_k127_291066_2	1229780.BN381_310078	4.293e-94	322.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR21617310_k127_291066_8	1120950.KB892755_gene5943	4.905e-10	70.0	COG2261@1|root,COG2261@2|Bacteria,2IQGM@201174|Actinobacteria,4DRWR@85009|Propionibacteriales	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR21617310_k127_291066_0	391623.TERMP_00992	1.095e-161	527.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR21617310_k127_291066_5	351607.Acel_1045	3.617e-72	257.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4EWCI@85013|Frankiales	201174|Actinobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR21617310_k127_291066_3	436229.JOEH01000039_gene2018	6.15e-91	310.0	COG1378@1|root,COG1378@2|Bacteria,2I334@201174|Actinobacteria,2NKY0@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TrmB
SRR21617310_k127_291066_4	1122611.KB903985_gene3825	7.882e-86	318.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4ENKK@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR21617310_k127_2911149_6	1172181.KB911713_gene4408	6.565e-37	141.0	COG0569@1|root,COG0569@2|Bacteria,2HB3U@201174|Actinobacteria	201174|Actinobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR21617310_k127_2911149_2	284031.JNXD01000003_gene3708	1.815e-70	250.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR21617310_k127_2911149_8	1157490.EL26_22590	2.345e-24	118.0	COG4447@1|root,COG4447@2|Bacteria,1V606@1239|Firmicutes,4IQ1A@91061|Bacilli	91061|Bacilli	S	cellulose binding	ycf48	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
SRR21617310_k127_2911149_5	1144275.COCOR_03695	1.415e-41	171.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2911149_11	1370125.AUWT01000090_gene2691	7.316e-06	58.0	2EHZ4@1|root,33BQK@2|Bacteria,2HBAR@201174|Actinobacteria,23EEH@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2911149_9	994479.GL877879_gene5479	1.807e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,2GUGU@201174|Actinobacteria,4E8EB@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2911149_3	479433.Caci_8293	8.732e-52	198.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT
SRR21617310_k127_2911149_0	105422.BBPM01000097_gene5229	7.597e-148	479.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,2NH21@228398|Streptacidiphilus	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_2911149_7	1030157.AFMP01000031_gene2989	6.288e-25	115.0	COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,2TU1P@28211|Alphaproteobacteria,2K28G@204457|Sphingomonadales	204457|Sphingomonadales	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR21617310_k127_2911149_4	1122182.KB903835_gene4256	1.959e-44	166.0	COG1478@1|root,COG1670@1|root,COG1478@2|Bacteria,COG1670@2|Bacteria,2HNQP@201174|Actinobacteria,4DFSH@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_2911149_1	350058.Mvan_2212	8.525e-126	416.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,233JN@1762|Mycobacteriaceae	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR21617310_k127_2920381_11	1440774.Y900_011240	5.411e-23	112.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,2330W@1762|Mycobacteriaceae	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR21617310_k127_2920381_12	103733.JNYO01000011_gene4879	3.179e-16	89.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria,4E4EE@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR21617310_k127_2920381_9	2002.JOEQ01000004_gene3007	3.95e-30	133.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4EIPF@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR21617310_k127_2920381_3	500153.JOEK01000002_gene606	3.396e-130	426.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR21617310_k127_2920381_2	1229780.BN381_10075	1.662e-134	442.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,3UXC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR21617310_k127_2920381_4	1313172.YM304_12530	1.48e-92	315.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR21617310_k127_2920381_8	1313172.YM304_12540	2.962e-38	157.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria	201174|Actinobacteria	A	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR21617310_k127_2920381_7	1123024.AUII01000006_gene4707	9.361e-51	186.0	COG0778@1|root,COG0778@2|Bacteria,2IPGB@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR21617310_k127_2920381_0	656024.FsymDg_1096	2.54e-177	568.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4EU61@85013|Frankiales	201174|Actinobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR21617310_k127_2920381_6	1430331.EP10_18360	1.095e-62	228.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR21617310_k127_2920381_5	471852.Tcur_4061	5.118e-65	237.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4EG56@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR21617310_k127_2920381_13	316067.Geob_2107	4.693e-14	77.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR21617310_k127_2920381_1	1157632.AQWQ01000008_gene4900	3.438e-162	526.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria	201174|Actinobacteria	G	the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells	manB	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR21617310_k127_2920381_10	365528.KB891181_gene4670	8.117e-26	114.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4ET6R@85013|Frankiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR21617310_k127_292361_11	211114.JOEF01000001_gene7070	7.962e-14	77.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4DXJ2@85010|Pseudonocardiales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR21617310_k127_292361_7	648996.Theam_0136	6.21e-85	288.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR21617310_k127_292361_2	1283299.AUKG01000005_gene78	1.813e-196	628.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR21617310_k127_292361_8	1123320.KB889707_gene7980	3.104e-70	248.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_292361_1	264732.Moth_0532	2.307e-297	938.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR21617310_k127_292361_0	471852.Tcur_1701	0.0	1097.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR21617310_k127_292361_5	1134445.AJJM01000021_gene4173	2.836e-102	360.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria	201174|Actinobacteria	H	Folylpolyglutamate synthase	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_292361_9	298654.FraEuI1c_1956	1.714e-53	191.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4ESUM@85013|Frankiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR21617310_k127_292361_3	656024.FsymDg_1524	7.655e-170	539.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4ES3S@85013|Frankiales	201174|Actinobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR21617310_k127_292361_10	1120936.KB907209_gene1850	3.839e-40	160.0	COG1792@1|root,COG1792@2|Bacteria,2GJN0@201174|Actinobacteria,4EGT6@85012|Streptosporangiales	201174|Actinobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR21617310_k127_292361_12	66875.JODY01000015_gene688	5.43e-11	74.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria	201174|Actinobacteria	M	rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR21617310_k127_292361_4	1306406.ASHX01000001_gene2782	1.633e-111	387.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria	201174|Actinobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR21617310_k127_292361_6	1394178.AWOO02000035_gene8984	2.882e-98	336.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4EFT6@85012|Streptosporangiales	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR21617310_k127_2927437_6	234267.Acid_7009	0.000103	53.0	COG1305@1|root,COG3063@1|root,COG3071@1|root,COG1305@2|Bacteria,COG3063@2|Bacteria,COG3071@2|Bacteria,3Y5KB@57723|Acidobacteria	57723|Acidobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR21617310_k127_2927437_2	446470.Snas_0348	1.378e-19	93.0	COG1403@1|root,COG1403@2|Bacteria,2INZ4@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2927437_1	679926.Mpet_2297	1.455e-86	306.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y00D@28890|Euryarchaeota	28890|Euryarchaeota	L	modification methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_2927437_0	1003195.SCAT_0615	5.947e-110	364.0	28MC2@1|root,2ZAQD@2|Bacteria,2IKMZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_2927437_7	1410653.JHVC01000013_gene3659	0.000314	51.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,1V7G8@1239|Firmicutes,248ER@186801|Clostridia,36E0H@31979|Clostridiaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1,SH3_3
SRR21617310_k127_2927437_3	1444310.JANV01000205_gene652	2.967e-10	71.0	COG0741@1|root,COG1196@1|root,COG4942@1|root,COG0741@2|Bacteria,COG1196@2|Bacteria,COG4942@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR21617310_k127_2927437_4	1229780.BN381_600013	1.848e-08	64.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_293301_1	285535.JOEY01000101_gene1733	5.016e-71	248.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria	201174|Actinobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR21617310_k127_293301_3	1348663.KCH_22960	1.945e-25	116.0	COG1309@1|root,COG1309@2|Bacteria,2HAGC@201174|Actinobacteria,2M3UA@2063|Kitasatospora	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR21617310_k127_293301_2	383372.Rcas_4342	8.183e-31	128.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,375U7@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR21617310_k127_293301_0	266117.Rxyl_2824	1.344e-149	486.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA1	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR21617310_k127_300648_0	518766.Rmar_2202	1.742e-180	579.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_300648_2	1380356.JNIK01000016_gene3559	3.928e-25	121.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4ERDT@85013|Frankiales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR21617310_k127_300648_1	883066.HMPREF9233_01393	2.443e-51	203.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4D3F9@85005|Actinomycetales	201174|Actinobacteria	U	Type II IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR21617310_k127_300648_3	1210046.B277_12161	1.414e-22	114.0	COG2064@1|root,COG2064@2|Bacteria,2GKMW@201174|Actinobacteria,4FENF@85021|Intrasporangiaceae	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_300648_4	1713.JOFV01000008_gene3105	4.6e-15	88.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4F0GG@85016|Cellulomonadaceae	201174|Actinobacteria	NU	PFAM Type II secretion system F domain	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR21617310_k127_300648_5	1122138.AQUZ01000058_gene3468	5.138e-05	55.0	2BJMZ@1|root,32DZH@2|Bacteria,2I1FG@201174|Actinobacteria,4DSHC@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR21617310_k127_301801_2	222534.KB893783_gene5310	3.475e-16	78.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_301801_1	1146883.BLASA_1503	2.659e-34	144.0	COG1403@1|root,COG1403@2|Bacteria,2I9UA@201174|Actinobacteria,4EV17@85013|Frankiales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_301801_3	471853.Bcav_1724	1.515e-15	84.0	COG1846@1|root,COG1846@2|Bacteria,2IMUX@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_301801_0	43759.JNWK01000013_gene6439	9.262e-50	182.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR21617310_k127_310544_3	653045.Strvi_6073	3.204e-20	91.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhfe	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR21617310_k127_310544_0	1121019.AUMN01000011_gene3376	7.154e-56	205.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_310544_1	298654.FraEuI1c_0934	2e-54	200.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4ETD3@85013|Frankiales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR21617310_k127_310544_2	749414.SBI_06422	1.711e-27	115.0	COG4274@1|root,COG4274@2|Bacteria,2IN0N@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR21617310_k127_310544_4	1869.MB27_07540	3.41e-07	55.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4DDGP@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_310778_0	543632.JOJL01000008_gene5597	2.332e-72	259.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DB3M@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_310778_2	1122609.AUGT01000003_gene2163	4.277e-17	88.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria,4DVRB@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_310778_3	391625.PPSIR1_13430	1.373e-11	71.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2WS0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR21617310_k127_310778_1	653045.Strvi_2661	3.773e-61	219.0	COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria	201174|Actinobacteria	NU	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR21617310_k127_312228_0	1463921.JODF01000001_gene3979	4.42e-125	408.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR21617310_k127_312228_1	67373.JOBF01000016_gene4809	3.157e-98	325.0	COG2197@1|root,COG2197@2|Bacteria,2GYMP@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_312228_3	1449346.JQMO01000003_gene2165	2.678e-75	260.0	COG1708@1|root,COG1708@2|Bacteria,2IFWR@201174|Actinobacteria	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR21617310_k127_312228_4	1298880.AUEV01000011_gene2653	3.128e-08	55.0	COG0500@1|root,COG0500@2|Bacteria,2I5J7@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_312228_2	1312954.KI914890_gene2145	9.986e-96	320.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,1WA0N@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_312228_5	697281.Mahau_0104	4.392e-05	51.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42G18@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_314779_6	996637.SGM_5748	6.479e-10	63.0	COG3292@1|root,COG3292@2|Bacteria,2I4DW@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR21617310_k127_314779_3	351607.Acel_0379	3.994e-62	225.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR21617310_k127_314779_7	1380370.JIBA01000011_gene3112	1.974e-05	56.0	2DRM0@1|root,33C8E@2|Bacteria,2GVJT@201174|Actinobacteria,4FHSM@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_314779_0	1172188.KB911829_gene4456	4.591e-189	609.0	COG4409@1|root,COG4409@2|Bacteria,2IEMG@201174|Actinobacteria,4FITI@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_314779_2	469371.Tbis_2760	1.198e-67	240.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR21617310_k127_314779_4	1380354.JIAN01000005_gene1778	1.826e-44	181.0	COG1928@1|root,COG1928@2|Bacteria,2IKRI@201174|Actinobacteria	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MIR
SRR21617310_k127_314779_5	1449355.JQNR01000005_gene2374	9.099e-13	74.0	2DRB9@1|root,33B2J@2|Bacteria,2GQE1@201174|Actinobacteria	201174|Actinobacteria	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR21617310_k127_314779_1	479432.Sros_1302	2.974e-70	247.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4EFXR@85012|Streptosporangiales	201174|Actinobacteria	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Yop-YscD_cpl
SRR21617310_k127_319716_2	591158.SSMG_08183	7.947e-15	74.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_319716_4	1089545.KB913037_gene942	2.317e-06	53.0	COG0457@1|root,COG0457@2|Bacteria,2INUN@201174|Actinobacteria,4DZ50@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_7
SRR21617310_k127_319716_1	1298858.AUEL01000011_gene5415	9.093e-28	119.0	COG1786@1|root,COG1786@2|Bacteria,1N5DN@1224|Proteobacteria,2UGA7@28211|Alphaproteobacteria,43KBA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
SRR21617310_k127_319716_0	1056816.JAFQ01000004_gene4732	1.1e-66	240.0	COG1679@1|root,COG1679@2|Bacteria,2GMWV@201174|Actinobacteria,4G74X@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR21617310_k127_319716_3	1185652.USDA257_c53550	4.554e-14	74.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2TTR6@28211|Alphaproteobacteria,4BJD8@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR21617310_k127_320167_4	211114.JOEF01000002_gene4590	1.605e-125	412.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4E3SI@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR21617310_k127_320167_7	469383.Cwoe_4790	3.848e-49	187.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CQ6X@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_320167_3	710111.FraQA3DRAFT_4194	2.223e-144	479.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ETNQ@85013|Frankiales	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_320167_2	1449353.JQMQ01000005_gene5392	8.355e-169	540.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_320167_0	1449347.JQLN01000003_gene5670	3.349e-199	635.0	COG0749@1|root,COG0749@2|Bacteria,2GM8R@201174|Actinobacteria,2M19Z@2063|Kitasatospora	201174|Actinobacteria	L	DNA polymerase family A	polA2	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A
SRR21617310_k127_320167_6	1150864.MILUP08_42328	1.126e-67	236.0	COG3358@1|root,COG3358@2|Bacteria,2IHE3@201174|Actinobacteria,4DCTC@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR21617310_k127_320167_8	1206730.BAGA01000138_gene3553	6.25e-41	158.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,4G1BR@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR21617310_k127_320167_5	1123023.JIAI01000013_gene3941	5.228e-86	299.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4E0V0@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_320167_1	266117.Rxyl_1701	4.749e-180	576.0	COG0154@1|root,COG0154@2|Bacteria,2GUUU@201174|Actinobacteria,4CR01@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_320494_0	66875.JODY01000006_gene2209	8.216e-150	488.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_320494_5	649831.L083_2190	2.867e-98	334.0	2D3F0@1|root,32TEU@2|Bacteria,2IDGD@201174|Actinobacteria,4DGEV@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_320494_13	1303692.SFUL_3721	4.26e-17	90.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria	201174|Actinobacteria	KT	Phage tail tape measure protein TP901	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,SLT
SRR21617310_k127_320494_14	1079986.JH164842_gene5985	1.681e-07	61.0	COG0515@1|root,COG3409@1|root,COG0515@2|Bacteria,COG3409@2|Bacteria,2GMAC@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PG_binding_1,Pkinase
SRR21617310_k127_320494_12	1003195.SCAT_5815	2.955e-18	85.0	2EK8X@1|root,33DZ6@2|Bacteria,2GWJW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_320494_11	471852.Tcur_2368	6.018e-56	205.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4EIVM@85012|Streptosporangiales	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR21617310_k127_320494_3	1394178.AWOO02000013_gene7822	1.827e-118	391.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4EG8Y@85012|Streptosporangiales	201174|Actinobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR21617310_k127_320494_10	1121877.JQKF01000002_gene1746	1.136e-64	240.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR21617310_k127_320494_1	266117.Rxyl_0933	3.118e-148	477.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR21617310_k127_320494_9	1120936.KB907210_gene5950	1.585e-68	247.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	HTH_30
SRR21617310_k127_320494_7	1120936.KB907208_gene1218	3.625e-87	296.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EN3G@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_320494_8	316057.RPD_3556	1.798e-83	289.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,3JSYB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	MA20_18600	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_320494_4	1120936.KB907208_gene1216	6.735e-113	371.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4EIQD@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_320494_6	1110697.NCAST_26_00530	1.917e-87	308.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4FXEZ@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_320494_2	1120936.KB907208_gene1214	1.045e-139	458.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4EJ41@85012|Streptosporangiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR21617310_k127_322627_1	67332.FM21_17290	3.482e-37	146.0	COG3415@1|root,COG3415@2|Bacteria,2IJ9E@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
SRR21617310_k127_322627_0	665577.JH993790_gene5690	3.54e-56	204.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR21617310_k127_323843_0	1120950.KB892790_gene2110	8.362e-269	837.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DNTS@85009|Propionibacteriales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR21617310_k127_323843_3	1906.SFRA_24745	5.891e-11	63.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_323843_1	1313172.YM304_04550	2.497e-103	360.0	COG2146@1|root,COG2146@2|Bacteria,2GQWS@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR21617310_k127_323843_2	585531.HMPREF0063_12710	1.282e-16	93.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4DWG7@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_324618_7	1120950.KB892819_gene7157	1.5e-06	51.0	2E5N2@1|root,330CX@2|Bacteria,2GUMX@201174|Actinobacteria,4DWAJ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_324618_6	110319.CF8_2355	2.366e-12	74.0	COG4974@1|root,COG4974@2|Bacteria,2GNKJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1
SRR21617310_k127_324618_3	1136417.AZWE01000024_gene696	2.348e-20	95.0	29WFB@1|root,30I16@2|Bacteria,2IRRK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_324618_0	1445613.JALM01000016_gene6172	2.27e-276	867.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4DXYH@85010|Pseudonocardiales	201174|Actinobacteria	Q	Copper amine oxidase, enzyme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR21617310_k127_324618_5	1968.JOEV01000036_gene1274	1.62e-15	82.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR21617310_k127_324618_1	479432.Sros_0422	3.288e-245	764.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4EM4B@85012|Streptosporangiales	201174|Actinobacteria	C	Acetamidase/Formamidase family	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR21617310_k127_324618_2	882.DVU_1160	2.229e-79	278.0	COG4413@1|root,COG4413@2|Bacteria,1N2FW@1224|Proteobacteria,43BA6@68525|delta/epsilon subdivisions,2WVBB@28221|Deltaproteobacteria,2MCDK@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Urea transporter	-	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009987,GO:0015204,GO:0015265,GO:0015267,GO:0015840,GO:0016020,GO:0016043,GO:0019755,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0033218,GO:0033219,GO:0036094,GO:0042802,GO:0042886,GO:0042887,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070206,GO:0070207,GO:0071702,GO:0071705,GO:0071840,GO:0071918,GO:0071944	-	ko:K08717	-	-	-	-	ko00000,ko02000	1.A.28.2	-	-	UT
SRR21617310_k127_326277_1	1246995.AFR_22775	1.005e-73	265.0	COG0657@1|root,COG0657@2|Bacteria,2I3E3@201174|Actinobacteria,4DMPD@85008|Micromonosporales	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_326277_0	1382304.JNIL01000001_gene3015	5.292e-132	433.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR21617310_k127_330533_0	479434.Sthe_2502	1.975e-137	456.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_330533_1	443143.GM18_0098	4.805e-16	89.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR21617310_k127_340215_10	485913.Krac_0608	5.47e-128	423.0	COG0477@1|root,COG0477@2|Bacteria,2G7N2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_340215_25	68260.JOAY01000021_gene1712	5.085e-29	134.0	COG1309@1|root,COG1309@2|Bacteria,2GX8K@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_340215_21	1379698.RBG1_1C00001G1271	3.899e-42	169.0	COG1630@1|root,COG1630@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR21617310_k127_340215_4	1379698.RBG1_1C00001G1269	1.384e-148	486.0	COG0433@1|root,COG0433@2|Bacteria,2NPZD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
SRR21617310_k127_340215_24	368407.Memar_1616	1.012e-34	148.0	COG0420@1|root,arCOG00397@2157|Archaea,2XT7A@28890|Euryarchaeota,2NA2J@224756|Methanomicrobia	224756|Methanomicrobia	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity	mre11	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
SRR21617310_k127_340215_22	861299.J421_2697	5.079e-41	175.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR21617310_k127_340215_30	656024.FsymDg_2569	3.209e-10	68.0	2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR21617310_k127_340215_17	391037.Sare_2388	4.895e-61	235.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4D8UB@85008|Micromonosporales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iNJ661.Rv2051c	CN_hydrolase
SRR21617310_k127_340215_14	1068978.AMETH_3494	9.859e-76	280.0	COG0463@1|root,COG0463@2|Bacteria,2IPT1@201174|Actinobacteria,4EFF1@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR21617310_k127_340215_5	219305.MCAG_03794	3.889e-146	474.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4DAEY@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR21617310_k127_340215_28	573413.Spirs_2677	4.688e-21	102.0	COG2050@1|root,COG2050@2|Bacteria,2JAD0@203691|Spirochaetes	203691|Spirochaetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_340215_18	1499967.BAYZ01000009_gene5268	1.395e-51	192.0	COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR21617310_k127_340215_7	469383.Cwoe_3116	2.509e-137	447.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4CPP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_340215_0	471852.Tcur_1129	3.565e-250	802.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4EFI8@85012|Streptosporangiales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR21617310_k127_340215_12	1122611.KB903974_gene3033	1.121e-87	297.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4EHM4@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS2	GO:0003674,GO:0003824,GO:0016740,GO:0016765,GO:0033850	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR21617310_k127_340215_26	909613.UO65_2182	2.575e-27	122.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4E3NH@85010|Pseudonocardiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR21617310_k127_340215_19	1382304.JNIL01000001_gene3165	7.011e-48	179.0	COG2818@1|root,COG2818@2|Bacteria,1V9B8@1239|Firmicutes,4HJ4I@91061|Bacilli	91061|Bacilli	L	3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR21617310_k127_340215_20	1961.JOAK01000009_gene6338	3.028e-43	181.0	2AJVX@1|root,31AIP@2|Bacteria,2GJIY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_340215_3	1961.JOAK01000009_gene6337	8.728e-158	513.0	COG1541@1|root,COG1541@2|Bacteria,2ICK2@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_340215_11	1123024.AUII01000001_gene3065	4.433e-119	394.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4E62H@85010|Pseudonocardiales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR21617310_k127_340215_13	670487.Ocepr_1763	3.187e-82	289.0	COG0128@1|root,COG0128@2|Bacteria,1WI9P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR21617310_k127_340215_15	1128421.JAGA01000002_gene1557	8.924e-71	265.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR21617310_k127_340215_2	926569.ANT_03310	7.015e-222	702.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR21617310_k127_340215_27	1123389.ATXJ01000004_gene1168	3.004e-24	108.0	28TIQ@1|root,2ZFSJ@2|Bacteria,1WK1S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_340215_8	58123.JOFJ01000027_gene2789	1.805e-133	443.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4EFPC@85012|Streptosporangiales	201174|Actinobacteria	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR21617310_k127_340215_6	1123023.JIAI01000001_gene6358	1.008e-143	460.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,4E06G@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR21617310_k127_340215_9	1521187.JPIM01000058_gene2537	3.477e-131	431.0	COG2170@1|root,COG2170@2|Bacteria,2G5NR@200795|Chloroflexi,375BI@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR21617310_k127_340215_29	103733.JNYO01000001_gene68	9.811e-14	77.0	COG5416@1|root,COG5416@2|Bacteria	2|Bacteria	FG	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR21617310_k127_340215_16	266117.Rxyl_0205	8.031e-69	243.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4CT8C@84995|Rubrobacteria	84995|Rubrobacteria	Q	Catechol dioxygenase N terminus	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
SRR21617310_k127_340215_1	196367.JNFG01000201_gene2745	7.189e-233	728.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39,1.2.1.8	ko:K00130,ko:K00146	ko00260,ko00360,ko00643,ko01100,ko01120,map00260,map00360,map00643,map01100,map01120	M00555	R02536,R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_340215_23	1245471.PCA10_31820	1.631e-39	148.0	28IZD@1|root,2Z8WU@2|Bacteria,1NEGQ@1224|Proteobacteria,1TBGG@1236|Gammaproteobacteria,1YHG9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_3443_5	656024.FsymDg_3866	1.002e-65	229.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ES7T@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_3443_3	1121928.AUHE01000010_gene2632	4.746e-80	280.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4GCBN@85026|Gordoniaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR21617310_k127_3443_7	66897.DJ64_21920	1.882e-57	209.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR21617310_k127_3443_2	1304883.KI912532_gene1157	2.996e-85	296.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,2KUAD@206389|Rhodocyclales	206389|Rhodocyclales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR21617310_k127_3443_8	2002.JOEQ01000004_gene2684	3.253e-54	201.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4EH8W@85012|Streptosporangiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR21617310_k127_3443_12	47716.JOFH01000023_gene3739	2.065e-13	76.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat,Tox-HNH-EHHH
SRR21617310_k127_3443_6	298654.FraEuI1c_0302	2.631e-58	221.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR21617310_k127_3443_0	518766.Rmar_1581	5.429e-190	604.0	COG0076@1|root,COG0076@2|Bacteria,4NGRW@976|Bacteroidetes,1FJ4Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
SRR21617310_k127_3443_4	1122611.KB903950_gene6445	2.024e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4EJM3@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_3443_1	656024.FsymDg_1722	1.332e-106	363.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_3443_9	882083.SacmaDRAFT_3182	1.755e-48	182.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR21617310_k127_3443_10	1089544.KB912942_gene214	6.933e-38	148.0	2DSM3@1|root,33GM1@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_347644_11	397278.JOJN01000009_gene3673	1.047e-15	80.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4DSSW@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR21617310_k127_347644_3	345341.KUTG_00490	1.712e-100	346.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR21617310_k127_347644_5	1382356.JQMP01000004_gene532	3.268e-67	237.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR21617310_k127_347644_10	1267533.KB906735_gene4634	1.664e-23	116.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	smuG	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR21617310_k127_347644_6	1146883.BLASA_4342	5.216e-65	231.0	COG1414@1|root,COG1414@2|Bacteria,2HGKI@201174|Actinobacteria,4EWKD@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR21617310_k127_347644_8	1298880.AUEV01000007_gene4715	1.238e-46	186.0	COG0599@1|root,COG0599@2|Bacteria,2IM8G@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Carboxymuconolactone decarboxylase	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR21617310_k127_347644_0	882083.SacmaDRAFT_3544	3.217e-121	399.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4E4VR@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_347644_7	485913.Krac_6598	1.901e-57	211.0	COG1396@1|root,COG1396@2|Bacteria,2G8I4@200795|Chloroflexi	200795|Chloroflexi	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_347644_9	593907.Celgi_0218	8.433e-42	157.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4F1FY@85016|Cellulomonadaceae	201174|Actinobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR21617310_k127_347644_4	67373.JOBF01000013_gene4267	1.891e-67	238.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR21617310_k127_347644_2	1449346.JQMO01000002_gene1313	9.505e-103	349.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,2M294@2063|Kitasatospora	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR21617310_k127_347644_1	981369.JQMJ01000004_gene412	2.557e-112	383.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,2NFU0@228398|Streptacidiphilus	201174|Actinobacteria	E	TOBE domain	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR21617310_k127_349205_7	479432.Sros_5735	1.344e-10	72.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4EG45@85012|Streptosporangiales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR21617310_k127_349205_9	710686.Mycsm_01608	0.0005067	45.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,236CI@1762|Mycobacteriaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR21617310_k127_349205_0	1380390.JIAT01000009_gene547	2.153e-275	859.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4CPAY@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR21617310_k127_349205_1	1173028.ANKO01000244_gene3949	5.402e-99	342.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR21617310_k127_349205_3	58123.JOFJ01000011_gene4744	6.461e-63	222.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4EQVD@85012|Streptosporangiales	201174|Actinobacteria	K	TENA/THI-4/PQQC family	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
SRR21617310_k127_349205_2	1313172.YM304_09930	2.11e-70	251.0	28TMF@1|root,2ZFV1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_349205_6	1828.JOKB01000019_gene1789	1.041e-18	99.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR21617310_k127_349205_5	1380390.JIAT01000009_gene2129	6.946e-56	204.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4CRF2@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR21617310_k127_349205_4	1160137.KB907307_gene358	3.97e-57	207.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4FUAR@85025|Nocardiaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR21617310_k127_349205_8	298654.FraEuI1c_6707	2.443e-06	50.0	COG3583@1|root,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
SRR21617310_k127_351084_6	1133849.O3I_014620	8.028e-40	154.0	2C4IS@1|root,2Z81U@2|Bacteria,2GP0Z@201174|Actinobacteria,4G4B5@85025|Nocardiaceae	201174|Actinobacteria	S	Lantibiotic dehydratase, C terminus	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
SRR21617310_k127_351084_8	391735.Veis_4380	1.633e-16	87.0	COG2050@1|root,COG2050@2|Bacteria,1RHP8@1224|Proteobacteria,2VWKH@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_351084_10	1038859.AXAU01000001_gene3762	1.816e-06	53.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,2UB9Y@28211|Alphaproteobacteria,3JXKA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_351084_5	1429916.X566_18985	1.081e-50	188.0	COG1309@1|root,COG1309@2|Bacteria,1R60G@1224|Proteobacteria,2TUEP@28211|Alphaproteobacteria,3JVVX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_12,TetR_N
SRR21617310_k127_351084_3	797209.ZOD2009_11920	1.768e-98	343.0	COG1960@1|root,arCOG04100@2157|Archaea,2XTBC@28890|Euryarchaeota,23U9N@183963|Halobacteria	183963|Halobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR21617310_k127_351084_4	479434.Sthe_0316	5.019e-65	235.0	COG2872@1|root,COG2872@2|Bacteria,2GA6P@200795|Chloroflexi,27XNC@189775|Thermomicrobia	189775|Thermomicrobia	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR21617310_k127_351084_1	134676.ACPL_1713	3.949e-141	456.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D9NZ@85008|Micromonosporales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.2.2	ko:K01781	ko00627,ko01120,map00627,map01120	-	R03791,R04161	RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR21617310_k127_351084_9	1370125.AUWT01000080_gene3767	7.2e-07	62.0	COG3039@1|root,COG3039@2|Bacteria,2IERV@201174|Actinobacteria,237W6@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
SRR21617310_k127_351084_2	1206731.BAGB01000012_gene2530	4.793e-111	370.0	COG2070@1|root,COG2070@2|Bacteria,2GKV4@201174|Actinobacteria,4FWIZ@85025|Nocardiaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR21617310_k127_351084_0	557599.MKAN_02550	2.062e-180	577.0	COG5421@1|root,COG5421@2|Bacteria,2GPCI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR21617310_k127_351084_7	1229780.BN381_370013	1.093e-16	88.0	2EACZ@1|root,334GV@2|Bacteria,2GP35@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_351114_4	1229780.BN381_220012	1.262e-67	244.0	COG2801@1|root,COG2801@2|Bacteria,2IEHA@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
SRR21617310_k127_351114_9	1123251.ATWM01000016_gene1407	2.287e-05	46.0	2E3WU@1|root,32YU0@2|Bacteria,2GTJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_351114_5	479431.Namu_2559	3.989e-25	106.0	2E3WU@1|root,32YU0@2|Bacteria,2GTJB@201174|Actinobacteria,4EX1G@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_351114_8	1521187.JPIM01000067_gene1080	3.662e-06	56.0	2E9YS@1|root,3344A@2|Bacteria,2G7FK@200795|Chloroflexi,376JY@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR21617310_k127_351114_10	1209984.BN978_01196	0.0001427	48.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,233YE@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_351114_7	1463936.JOJI01000034_gene2534	1.444e-14	79.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_351114_6	1894.JOER01000033_gene4236	4.194e-25	115.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	insA	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_351114_1	1380354.JIAN01000011_gene3239	8.557e-104	344.0	COG0656@1|root,COG0656@2|Bacteria,2HGQC@201174|Actinobacteria,4F29H@85016|Cellulomonadaceae	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_351114_2	656024.FsymDg_3867	7.85e-76	276.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4EVAJ@85013|Frankiales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_351114_0	656024.FsymDg_3866	1.06e-104	348.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ES7T@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_351114_3	882082.SaccyDRAFT_2260	3.153e-70	245.0	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria,4E749@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_352131_3	40571.JOEA01000037_gene6777	3.262e-55	209.0	COG0248@1|root,COG2951@1|root,COG0248@2|Bacteria,COG2951@2|Bacteria,2GJBN@201174|Actinobacteria,4E04G@85010|Pseudonocardiales	201174|Actinobacteria	FP	PFAM Ppx GppA phosphatase	ppx2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR21617310_k127_352131_4	1144275.COCOR_00615	8.707e-42	173.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2YXU5@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR21617310_k127_352131_5	102125.Xen7305DRAFT_00016140	2.596e-31	141.0	COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VI2D@52604|Pleurocapsales	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR21617310_k127_352131_0	1242864.D187_004550	1.845e-221	728.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
SRR21617310_k127_352131_2	1463854.JOHT01000016_gene7046	9.095e-186	595.0	COG3200@1|root,COG3200@2|Bacteria,2ICP9@201174|Actinobacteria	201174|Actinobacteria	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR21617310_k127_352131_1	1123072.AUDH01000001_gene3181	5.559e-212	676.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JR19@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_361199_8	383372.Rcas_3282	4.436e-86	297.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR21617310_k127_361199_10	479434.Sthe_0904	1.399e-67	250.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_361199_11	1128421.JAGA01000002_gene1655	3.303e-54	209.0	COG0438@1|root,COG0438@2|Bacteria,2NR3F@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_361199_5	298653.Franean1_5894	7.657e-103	348.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4ERHJ@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_361199_1	656024.FsymDg_1051	2.104e-154	503.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ET5X@85013|Frankiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR21617310_k127_361199_4	298654.FraEuI1c_6091	1.581e-110	370.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4EUCZ@85013|Frankiales	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR21617310_k127_361199_7	656024.FsymDg_1053	1.104e-90	308.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4ESU0@85013|Frankiales	201174|Actinobacteria	GM	Transport permease protein	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_361199_0	222534.KB893683_gene1179	5.516e-181	580.0	COG0438@1|root,COG0438@2|Bacteria,2IJ4J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_361199_13	525909.Afer_0107	5.424e-28	129.0	COG0030@1|root,COG0438@1|root,COG0030@2|Bacteria,COG0438@2|Bacteria,2HGIU@201174|Actinobacteria,4CNHI@84992|Acidimicrobiia	84992|Acidimicrobiia	JM	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR21617310_k127_361199_6	1206730.BAGA01000184_gene3108	6.218e-92	316.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4FVK3@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR21617310_k127_361199_9	1121346.KB899817_gene3225	2.575e-75	276.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR21617310_k127_361199_2	521011.Mpal_2404	1.106e-120	405.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR21617310_k127_361199_14	235985.BBPN01000031_gene2174	1.05e-24	120.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria,2NF68@228398|Streptacidiphilus	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_361199_12	656024.FsymDg_3902	5.297e-50	203.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR21617310_k127_361199_3	326424.FRAAL4397	1.755e-111	393.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_376153_1	1068978.AMETH_3308	2.421e-84	289.0	2CF7S@1|root,2ZB6P@2|Bacteria,2H77W@201174|Actinobacteria,4ECRE@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_376153_0	1121440.AUMA01000006_gene1658	6.847e-94	327.0	COG2519@1|root,COG2519@2|Bacteria,1MYHZ@1224|Proteobacteria	1224|Proteobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR21617310_k127_376372_0	656024.FsymDg_0937	1.293e-130	436.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4ERVJ@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR21617310_k127_376372_2	356851.JOAN01000017_gene5966	5.736e-56	220.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4D9ZI@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR21617310_k127_376372_1	1313172.YM304_09040	2.032e-117	390.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR21617310_k127_376372_3	479433.Caci_7932	3.927e-31	136.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR21617310_k127_376372_4	222534.KB893670_gene3666	6.229e-16	90.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4ERD1@85013|Frankiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR21617310_k127_379726_23	370438.PTH_0241	4.038e-20	96.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia,26026@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR21617310_k127_379726_22	1394178.AWOO02000030_gene4759	2.1e-26	126.0	COG2197@1|root,COG2197@2|Bacteria,2GJ5I@201174|Actinobacteria,4EPKH@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_379726_2	316067.Geob_2386	8.381e-190	621.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,43RZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	elongation factor Tu domain 2 protein	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR21617310_k127_379726_21	266117.Rxyl_2978	3.182e-29	124.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR21617310_k127_379726_15	882083.SacmaDRAFT_3409	9.321e-61	229.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4E0NM@85010|Pseudonocardiales	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR21617310_k127_379726_8	1245475.ANAE01000176_gene5138	5.246e-89	314.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4EGYP@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR21617310_k127_379726_25	309801.trd_A0858	1.14e-06	59.0	2AZF8@1|root,31RP4@2|Bacteria,2GBAW@200795|Chloroflexi,27YKD@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_379726_17	1313172.YM304_19800	4.975e-41	167.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CNA7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR21617310_k127_379726_3	1120950.KB892708_gene4269	5.099e-149	475.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DNEB@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR21617310_k127_379726_14	68570.DC74_1978	7.241e-66	232.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR21617310_k127_379726_10	1236541.BALL01000050_gene4249	1.948e-82	281.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,2Q8RY@267890|Shewanellaceae	1236|Gammaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR21617310_k127_379726_19	1123321.KB905813_gene1106	1.723e-39	155.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR21617310_k127_379726_18	1043493.BBLU01000001_gene812	2.733e-40	157.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR21617310_k127_379726_5	1229780.BN381_50110	7.982e-130	436.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,3UWC6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR21617310_k127_379726_24	1313172.YM304_19920	1.438e-14	79.0	COG1862@1|root,COG1862@2|Bacteria,2GXK0@201174|Actinobacteria	201174|Actinobacteria	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR21617310_k127_379726_12	696281.Desru_2378	4.738e-73	253.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,2608F@186807|Peptococcaceae	186801|Clostridia	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR21617310_k127_379726_6	1713.JOFV01000007_gene2990	3.966e-91	318.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4F1XH@85016|Cellulomonadaceae	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR21617310_k127_379726_7	351607.Acel_1340	3.012e-89	309.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4ERCU@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR21617310_k127_379726_13	1120936.KB907223_gene2482	1.524e-67	233.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4EIYA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR21617310_k127_379726_0	1120936.KB907223_gene2483	6.878e-294	921.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4EHMX@85012|Streptosporangiales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR21617310_k127_379726_16	292459.STH2430	8.325e-43	166.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR21617310_k127_379726_20	1229780.BN381_100130	5.66e-34	146.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,3UWKX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRR21617310_k127_379726_9	58123.JOFJ01000017_gene4158	2.599e-86	293.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4EHV3@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR21617310_k127_379726_4	471852.Tcur_2121	1.791e-130	430.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4EGCH@85012|Streptosporangiales	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR21617310_k127_379726_1	760568.Desku_2051	2.481e-198	635.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR21617310_k127_379726_11	479434.Sthe_0425	5.358e-78	266.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,27XS9@189775|Thermomicrobia	189775|Thermomicrobia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR21617310_k127_381342_0	861299.J421_1128	1.618e-218	707.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR21617310_k127_381342_1	861299.J421_0284	2.789e-107	351.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_381342_2	234267.Acid_1737	6.098e-31	124.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR21617310_k127_389610_0	570268.ANBB01000006_gene5431	5.121e-109	365.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4EFZA@85012|Streptosporangiales	201174|Actinobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_389610_3	1206725.BAFU01000026_gene2659	2.226e-18	87.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4G5CG@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_389610_2	525909.Afer_0302	1.22e-22	100.0	COG2963@1|root,COG2963@2|Bacteria,2GRDS@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Transposase IS3	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR21617310_k127_389610_4	525909.Afer_1051	4.154e-13	76.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CNY5@84992|Acidimicrobiia	84992|Acidimicrobiia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
SRR21617310_k127_389610_1	1136417.AZWE01000066_gene1147	5.579e-27	116.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D9V4@85008|Micromonosporales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_403634_7	882083.SacmaDRAFT_0257	2.874e-40	161.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DZ35@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_403634_13	1120949.KB903345_gene1563	2.409e-12	68.0	COG5520@1|root,COG5520@2|Bacteria,2I32Z@201174|Actinobacteria,4D8WH@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 59	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_59,Laminin_G_3,RicinB_lectin_2,Ricin_B_lectin
SRR21617310_k127_403634_12	1463825.JNXC01000012_gene1907	1.606e-19	100.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DZGD@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_403634_5	100226.SCO7642	8.5e-47	171.0	COG0346@1|root,COG0346@2|Bacteria,2IS2C@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_403634_6	1996.JOFO01000001_gene3942	5.59e-45	163.0	COG2002@1|root,COG2002@2|Bacteria,2I3FX@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR21617310_k127_403634_18	1054860.KB913030_gene2884	0.0003502	49.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	pedD	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR21617310_k127_403634_10	479432.Sros_2146	1.524e-32	132.0	COG0596@1|root,COG0596@2|Bacteria,2GU04@201174|Actinobacteria,4EPP1@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_403634_3	1120934.KB894403_gene213	9.948e-50	184.0	COG3467@1|root,COG3467@2|Bacteria,2IG17@201174|Actinobacteria,4E5M4@85010|Pseudonocardiales	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_403634_11	1206733.BAGC01000044_gene848	2.16e-32	133.0	2EHMA@1|root,33BD2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_403634_1	1133849.O3I_018745	5.058e-65	230.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0Z8@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR21617310_k127_403634_0	369723.Strop_0230	0.0	1052.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DBBY@85008|Micromonosporales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR21617310_k127_403634_14	369723.Strop_1254	4.159e-11	68.0	2EF4J@1|root,338XQ@2|Bacteria,2IGXH@201174|Actinobacteria,4DKSC@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_403634_15	656024.FsymDg_0945	7.024e-10	63.0	COG1813@1|root,COG1813@2|Bacteria,2IS8A@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR21617310_k127_403634_8	656024.FsymDg_0946	2.22e-33	133.0	COG1324@1|root,COG1324@2|Bacteria,2HU1X@201174|Actinobacteria,4EWGX@85013|Frankiales	201174|Actinobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR21617310_k127_403634_4	1120949.KB903294_gene4051	3.339e-49	186.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_403634_2	928724.SacglDRAFT_01218	6.514e-53	191.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4E51C@85010|Pseudonocardiales	201174|Actinobacteria	P	TIGRFAM deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_411455_5	208439.AJAP_28865	1.028e-44	180.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR21617310_k127_411455_1	219305.MCAG_04342	9.902e-87	294.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DBZU@85008|Micromonosporales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_411455_2	469383.Cwoe_4993	1.736e-64	233.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran
SRR21617310_k127_411455_3	994479.GL877879_gene5009	2.42e-63	232.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4E17N@85010|Pseudonocardiales	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR21617310_k127_411455_6	521098.Aaci_2277	1.027e-27	126.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli	91061|Bacilli	G	Periplasmic substrate-binding component of the ATP-dependent ribose transport system	rbsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR21617310_k127_411455_4	1121861.KB899912_gene1123	2.102e-46	188.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR21617310_k127_411455_7	1160137.KB907308_gene7582	1.462e-09	64.0	COG0477@1|root,COG2814@2|Bacteria,2GW3V@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_411455_0	247156.NFA_12060	2.262e-94	331.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria,4FYW4@85025|Nocardiaceae	201174|Actinobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR21617310_k127_417490_0	469383.Cwoe_4156	6.8e-99	330.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CP6Q@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_417490_8	1298920.KI911353_gene1967	1.163e-16	89.0	COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,24N86@186801|Clostridia,220PB@1506553|Lachnoclostridium	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR21617310_k127_417490_2	1123258.AQXZ01000016_gene2472	6.01e-78	275.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4FU70@85025|Nocardiaceae	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigB	GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_417490_3	326424.FRAAL2315	1.613e-48	183.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR21617310_k127_417490_1	269800.Tfu_1927	5.402e-91	316.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4EG7S@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR21617310_k127_417490_6	1123024.AUII01000038_gene4084	6.413e-30	129.0	COG0685@1|root,COG0685@2|Bacteria,2GJ6U@201174|Actinobacteria,4E9VR@85010|Pseudonocardiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR21617310_k127_417490_7	110319.CF8_4119	2.764e-23	110.0	COG0586@1|root,COG0671@1|root,COG1216@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4DTVA@85009|Propionibacteriales	201174|Actinobacteria	I	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR21617310_k127_417490_5	1121943.KB899991_gene2356	2.275e-32	134.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1S1J7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Cardiolipin synthetase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR21617310_k127_417490_4	1380356.JNIK01000018_gene589	8.515e-33	144.0	COG0671@1|root,COG0671@2|Bacteria,2IAUJ@201174|Actinobacteria,4EW1N@85013|Frankiales	201174|Actinobacteria	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF2189,PAP2
SRR21617310_k127_420096_0	1136417.AZWE01000051_gene3906	6.569e-265	855.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR21617310_k127_420096_1	711393.AYRX01000104_gene5867	4.352e-201	661.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding,Thioesterase
SRR21617310_k127_421271_0	644283.Micau_2846	9.973e-175	574.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR21617310_k127_421271_2	644283.Micau_2844	8.642e-06	52.0	2AGY4@1|root,3176Q@2|Bacteria,2HBIZ@201174|Actinobacteria,4DKB1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_421271_1	395495.Lcho_0069	4.463e-44	169.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria,1KNUH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K14588	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_421750_12	1128421.JAGA01000002_gene1228	1.59e-31	132.0	COG1801@1|root,COG1801@2|Bacteria,2NPRG@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR21617310_k127_421750_0	1122182.KB903813_gene2604	2.058e-121	402.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4DAM6@85008|Micromonosporales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR21617310_k127_421750_3	298655.KI912266_gene1102	1.451e-78	297.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR21617310_k127_421750_14	78346.BRUM_0021	8.137e-20	106.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR21617310_k127_421750_9	1540221.JQNI01000004_gene326	4.71e-46	172.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR21617310_k127_421750_8	591001.Acfer_1655	7.362e-47	176.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4H4BA@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR21617310_k127_421750_4	1163671.JAGI01000002_gene3191	1.243e-68	261.0	COG2605@1|root,COG2605@2|Bacteria,1V0XM@1239|Firmicutes,25D2P@186801|Clostridia,36U63@31979|Clostridiaceae	186801|Clostridia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR21617310_k127_421750_1	649831.L083_1913	1.36e-112	375.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DB93@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferases group 1	pimB	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_421750_5	981369.JQMJ01000004_gene3992	2.833e-68	255.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,2NHJ4@228398|Streptacidiphilus	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR21617310_k127_421750_11	66377.JOBH01000007_gene2063	3.966e-38	166.0	COG0308@1|root,COG0308@2|Bacteria,2GK29@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_421750_7	351607.Acel_0971	2.609e-47	184.0	COG0791@1|root,COG4942@1|root,COG0791@2|Bacteria,COG4942@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_421750_13	1463857.JOFZ01000012_gene1702	3.204e-24	118.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria	201174|Actinobacteria	M	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR21617310_k127_421750_15	196162.Noca_3127	3.735e-16	86.0	2ES7R@1|root,33JSG@2|Bacteria,2IQ6C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_421750_6	562970.Btus_1442	1.449e-58	215.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,2784M@186823|Alicyclobacillaceae	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR21617310_k127_421750_10	298653.Franean1_0040	8.66e-43	163.0	COG4974@1|root,COG4974@2|Bacteria,2HZZ8@201174|Actinobacteria,4EV64@85013|Frankiales	201174|Actinobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_421750_2	1123023.JIAI01000001_gene7370	5.008e-80	272.0	COG3665@1|root,COG3665@2|Bacteria,2GKI6@201174|Actinobacteria	201174|Actinobacteria	S	TIGRFAM Urea carboxylase-associated protein 1	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
SRR21617310_k127_421750_16	1440774.Y900_029675	5.265e-05	51.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria,23905@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_423155_1	221288.JH992901_gene804	1.531e-289	927.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JKTF@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
SRR21617310_k127_423155_0	211165.AJLN01000149_gene6654	0.0	1127.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JI65@1189|Stigonemataceae	1117|Cyanobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
SRR21617310_k127_423308_2	298655.KI912267_gene7987	1.982e-16	81.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4EVT4@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_423308_1	1449355.JQNR01000005_gene3791	9.034e-40	163.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR21617310_k127_423308_0	390989.JOEG01000001_gene5108	2.051e-57	205.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DDFZ@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR21617310_k127_423308_3	1394178.AWOO02000046_gene6511	8.675e-07	60.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2I90E@201174|Actinobacteria,4EIFN@85012|Streptosporangiales	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR21617310_k127_423610_8	211114.JOEF01000007_gene1032	4.059e-18	85.0	COG3899@1|root,COG3899@2|Bacteria,2HETF@201174|Actinobacteria,4EBUT@85010|Pseudonocardiales	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_423610_1	1210884.HG799463_gene9923	2.783e-78	273.0	COG1878@1|root,COG1878@2|Bacteria,2J1IQ@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR21617310_k127_423610_3	1267533.KB906734_gene3822	1.556e-62	218.0	2B5NQ@1|root,31YI3@2|Bacteria,3Y9FC@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR21617310_k127_423610_2	298655.KI912266_gene1639	1.917e-65	231.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria,4EVT6@85013|Frankiales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
SRR21617310_k127_423610_4	83332.Rv2829c	4.64e-57	205.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR21617310_k127_423610_7	83332.Rv2830c	1.973e-24	109.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR21617310_k127_423610_0	1122138.AQUZ01000019_gene8120	8.997e-142	460.0	29FX3@1|root,302US@2|Bacteria,2IIAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_423610_5	710111.FraQA3DRAFT_1228	4.625e-40	153.0	arCOG05205@1|root,32ZUE@2|Bacteria,2IT0A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_428408_4	1394178.AWOO02000040_gene8560	2.39e-78	269.0	COG0477@1|root,COG2814@2|Bacteria,2HRV9@201174|Actinobacteria,4EP3I@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_428408_7	1380346.JNIH01000007_gene1846	3.816e-53	196.0	COG0454@1|root,COG0456@2|Bacteria,2IAC7@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside 2'-N-acetyltransferase	aac	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR21617310_k127_428408_0	1123023.JIAI01000001_gene6535	2.442e-182	588.0	COG1914@1|root,COG1914@2|Bacteria,2GMUT@201174|Actinobacteria,4E7I6@85010|Pseudonocardiales	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_428408_8	47839.CCAU010000001_gene3096	9.269e-45	165.0	COG4319@1|root,COG4319@2|Bacteria,2IPRQ@201174|Actinobacteria,23AH0@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR21617310_k127_428408_10	1283283.ATXA01000004_gene4354	1.184e-29	134.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	sumf2	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR21617310_k127_428408_3	1370121.AUWS01000097_gene3462	7.025e-94	340.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,235ZJ@1762|Mycobacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_428408_5	1237500.ANBA01000014_gene5585	3.36e-67	244.0	COG2318@1|root,COG2318@2|Bacteria,2II7R@201174|Actinobacteria,4EPYM@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_428408_6	365528.KB891260_gene499	1.68e-60	212.0	COG3339@1|root,COG3339@2|Bacteria,2IMCR@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR21617310_k127_428408_2	1206744.BAGL01000076_gene3175	5.087e-95	323.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4FXY5@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA5	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_428408_1	357808.RoseRS_0965	2.339e-137	443.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR21617310_k127_428408_9	1265310.CCBD010000064_gene1081	2.632e-43	168.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,235Q5@1762|Mycobacteriaceae	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR21617310_k127_434965_5	443218.AS9A_1887	3.403e-37	152.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,234JZ@1762|Mycobacteriaceae	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR21617310_k127_434965_3	1184609.KILIM_005_00810	3.308e-52	201.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4F6FW@85018|Dermatophilaceae	201174|Actinobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR21617310_k127_434965_2	656024.FsymDg_1697	7.622e-90	299.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4ES5V@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR21617310_k127_434965_0	760568.Desku_3294	5.24e-137	446.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR21617310_k127_434965_1	1229780.BN381_80403	3.405e-94	315.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,3UWH0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR21617310_k127_434965_6	1229203.KI301992_gene1276	2.008e-16	85.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,3UWW8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR21617310_k127_434965_4	700015.Corgl_1245	3.859e-44	180.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CUJQ@84998|Coriobacteriia	201174|Actinobacteria	E	pathway, signal sequence	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR21617310_k127_439768_4	67352.JODS01000011_gene4255	3.063e-34	135.0	COG5297@1|root,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CelD_N,Glyco_hydro_9
SRR21617310_k127_439768_0	479432.Sros_0936	5.796e-311	977.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4EFZ0@85012|Streptosporangiales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
SRR21617310_k127_439768_3	479432.Sros_0936	1.966e-80	277.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4EFZ0@85012|Streptosporangiales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
SRR21617310_k127_439768_2	298654.FraEuI1c_6917	5.098e-105	355.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4ES57@85013|Frankiales	201174|Actinobacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR21617310_k127_439768_1	479433.Caci_5330	9.847e-159	514.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	cebE	-	-	ko:K10240	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	SBP_bac_8
SRR21617310_k127_439768_5	981369.JQMJ01000004_gene4012	3.02e-12	68.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,2NJ16@228398|Streptacidiphilus	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR21617310_k127_44348_7	882083.SacmaDRAFT_0035	1.526e-28	126.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,4E13W@85010|Pseudonocardiales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT,SLT_2
SRR21617310_k127_44348_9	1429046.RR21198_0365	7.257e-12	76.0	COG0741@1|root,COG0741@2|Bacteria,2HKTH@201174|Actinobacteria	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_44348_8	1240350.AMZE01000047_gene288	1.827e-12	76.0	COG4454@1|root,COG4454@2|Bacteria,1N7A1@1224|Proteobacteria	1224|Proteobacteria	P	Copper-binding protein	cusF	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR21617310_k127_44348_0	479432.Sros_0556	9.847e-159	514.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4EG8W@85012|Streptosporangiales	201174|Actinobacteria	H	Aminotransferase class-III	hemL	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR21617310_k127_44348_4	1128421.JAGA01000001_gene2424	1.503e-57	214.0	COG0667@1|root,COG0667@2|Bacteria,2NPI2@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_44348_6	1120936.KB907208_gene909	7.757e-53	194.0	2AZDP@1|root,31RMA@2|Bacteria,2GUFH@201174|Actinobacteria,4EHPR@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR21617310_k127_44348_1	1382306.JNIM01000001_gene221	1.098e-151	487.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR21617310_k127_44348_2	1237500.ANBA01000006_gene2552	1.238e-120	411.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4EHK2@85012|Streptosporangiales	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR21617310_k127_44348_3	1236902.ANAS01000023_gene3284	1.608e-116	392.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4EFJQ@85012|Streptosporangiales	201174|Actinobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR21617310_k127_446776_9	345341.KUTG_07934	9.228e-16	79.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXU1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_446776_8	345341.KUTG_07933	2.444e-48	188.0	2E8I5@1|root,332W5@2|Bacteria,2GRF8@201174|Actinobacteria,4E68Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_446776_10	1434929.X946_1407	5.41e-13	82.0	2BTYX@1|root,32P7E@2|Bacteria,1PIJH@1224|Proteobacteria,2W763@28216|Betaproteobacteria,1KDWY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_446776_12	1157490.EL26_13165	0.0001243	51.0	COG4633@1|root,COG4633@2|Bacteria,1VHHU@1239|Firmicutes,4HNJT@91061|Bacilli,27AKT@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR21617310_k127_446776_2	867845.KI911784_gene635	4.383e-161	533.0	COG0318@1|root,COG0318@2|Bacteria,2G83V@200795|Chloroflexi,376U1@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_446776_4	357808.RoseRS_4344	2.488e-94	329.0	COG1893@1|root,COG1893@2|Bacteria,2GAI6@200795|Chloroflexi,376A7@32061|Chloroflexia	32061|Chloroflexia	H	2-dehydropantoate 2-reductase	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR21617310_k127_446776_5	1068978.AMETH_6468	9.217e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,2IP4P@201174|Actinobacteria,4E5RD@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_446776_0	644283.Micau_3557	4.46e-285	909.0	COG3227@1|root,COG3227@2|Bacteria,2GMQS@201174|Actinobacteria,4DG4Q@85008|Micromonosporales	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,Peptidase_M36
SRR21617310_k127_446776_11	58123.JOFJ01000007_gene710	5.98e-06	52.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4EIED@85012|Streptosporangiales	201174|Actinobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR21617310_k127_446776_7	469383.Cwoe_4817	1.564e-53	211.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4CQ7G@84995|Rubrobacteria	84995|Rubrobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR21617310_k127_446776_3	656024.FsymDg_0456	1.006e-136	452.0	COG0815@1|root,COG0815@2|Bacteria,2GP5I@201174|Actinobacteria,4EX2Z@85013|Frankiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR21617310_k127_446776_1	471857.Svir_30180	2.039e-225	707.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DYJK@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD3	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_446776_6	690850.Desaf_2977	1.519e-65	232.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria,2M9ST@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR21617310_k127_451810_2	1386089.N865_03620	8.74e-64	220.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4FGQ0@85021|Intrasporangiaceae	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR21617310_k127_451810_1	1380386.JIAW01000012_gene1867	6.492e-72	245.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,23327@1762|Mycobacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR21617310_k127_451810_0	710111.FraQA3DRAFT_3876	1.324e-321	998.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4ERUQ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR21617310_k127_451810_3	710111.FraQA3DRAFT_3875	2.687e-17	83.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR21617310_k127_45295_1	1206729.BAFZ01000042_gene4671	4.437e-29	133.0	COG1309@1|root,COG1309@2|Bacteria,2GVR4@201174|Actinobacteria,4G42E@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_45295_0	1288079.AUKN01000025_gene1482	1.228e-104	355.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3332	Amidohydro_1
SRR21617310_k127_45295_2	1501230.ET33_07475	2.3e-06	58.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,26STR@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR21617310_k127_455935_0	1205680.CAKO01000002_gene2993	2.285e-217	687.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria,2JV2S@204441|Rhodospirillales	204441|Rhodospirillales	S	benzoyl-CoA oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_455935_1	298655.KI912266_gene6270	4.219e-120	396.0	COG1024@1|root,COG1024@2|Bacteria,2GMNR@201174|Actinobacteria,4EU2N@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR21617310_k127_456039_4	479435.Kfla_2226	2.443e-65	230.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4DTNN@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_456039_9	1463856.JOHY01000002_gene1320	6.819e-17	90.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR21617310_k127_456039_1	378806.STAUR_0036	1.527e-99	340.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major facilitator superfamily	MA20_25180	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_456039_5	1380390.JIAT01000009_gene2005	2.722e-50	192.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR21617310_k127_456039_6	35754.JNYJ01000010_gene1662	1.742e-45	173.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4DE5M@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR21617310_k127_456039_7	1380390.JIAT01000013_gene222	1.086e-41	158.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CS38@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_456039_8	290397.Adeh_0115	1.721e-25	121.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_456039_0	33876.JNXY01000042_gene3809	2.552e-131	437.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DBFV@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_456039_3	479433.Caci_8342	3.443e-81	284.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_456039_10	1121396.KB893035_gene3615	7.995e-07	62.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2MHTJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR21617310_k127_456039_2	1382306.JNIM01000001_gene4028	1.131e-81	281.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR21617310_k127_466307_4	1095767.CAHD01000203_gene2335	6.689e-08	60.0	2E4ST@1|root,32ZM5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR21617310_k127_466307_3	479433.Caci_4037	1.227e-10	70.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria	201174|Actinobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR21617310_k127_466307_0	369723.Strop_2409	1.266e-52	196.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DDQM@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_466307_2	479431.Namu_2762	1.307e-14	88.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ESCA@85013|Frankiales	201174|Actinobacteria	U	Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR21617310_k127_474672_2	58123.JOFJ01000001_gene3044	1.967e-113	377.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4EH19@85012|Streptosporangiales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_474672_0	1048339.KB913029_gene4580	3.481e-115	392.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4EREQ@85013|Frankiales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_474672_1	106370.Francci3_1412	4.822e-115	380.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4ERUH@85013|Frankiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR21617310_k127_474672_4	326424.FRAAL2194	2.689e-102	351.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4ERI0@85013|Frankiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_474672_5	1048339.KB913029_gene4577	2.107e-93	327.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4ES9A@85013|Frankiales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR21617310_k127_474672_6	67275.JOAP01000097_gene73	8.245e-67	258.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR21617310_k127_474672_3	1211815.CBYP010000009_gene407	2.117e-106	362.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4ERUC@85013|Frankiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR21617310_k127_474672_7	1313172.YM304_19480	1.096e-56	213.0	COG0812@1|root,COG0812@2|Bacteria,2HG0Y@201174|Actinobacteria,4CMXR@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR21617310_k127_474672_8	1223543.GP2_001_00030	9.692e-12	76.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4GCTK@85026|Gordoniaceae	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR21617310_k127_48387_3	1000565.METUNv1_03865	2.446e-12	79.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,2KW5F@206389|Rhodocyclales	206389|Rhodocyclales	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
SRR21617310_k127_48387_0	1907.SGLAU_20815	8.464e-113	374.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR21617310_k127_48387_2	266940.Krad_3968	4.755e-26	122.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria	201174|Actinobacteria	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR21617310_k127_48387_5	1380356.JNIK01000013_gene4289	1.525e-06	60.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4ET93@85013|Frankiales	201174|Actinobacteria	L	Nudix hydrolase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR21617310_k127_48387_4	471856.Jden_2340	1.271e-09	66.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR21617310_k127_48387_1	656024.FsymDg_0998	6.808e-48	184.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR21617310_k127_486555_0	1382356.JQMP01000001_gene821	1.543e-66	232.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,27YY6@189775|Thermomicrobia	189775|Thermomicrobia	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR21617310_k127_486555_1	1382356.JQMP01000001_gene821	1.873e-32	139.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,27YY6@189775|Thermomicrobia	189775|Thermomicrobia	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR21617310_k127_486555_4	570268.ANBB01000008_gene4658	9.935e-12	73.0	COG1252@1|root,COG1252@2|Bacteria,2GKC0@201174|Actinobacteria,4EIQG@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR21617310_k127_486555_3	1123322.KB904680_gene3315	1.431e-13	74.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_486555_2	1120950.KB892774_gene1242	3.739e-23	100.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNDC@85009|Propionibacteriales	201174|Actinobacteria	P	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_488287_0	1120950.KB892779_gene892	3.463e-287	940.0	COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,2I35N@201174|Actinobacteria	201174|Actinobacteria	M	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
SRR21617310_k127_488287_4	2002.JOEQ01000017_gene7846	2.605e-99	344.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_488287_3	1380393.JHVP01000008_gene4623	8.435e-117	389.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4EUC2@85013|Frankiales	201174|Actinobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Glyco_hydro_6
SRR21617310_k127_488287_7	35754.JNYJ01000015_gene8556	1.93e-79	275.0	2DBMF@1|root,2Z9YG@2|Bacteria,2I871@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_488287_5	35754.JNYJ01000003_gene6543	4.672e-86	298.0	COG0463@1|root,COG0463@2|Bacteria,2I3C0@201174|Actinobacteria,4DH93@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR21617310_k127_488287_6	467200.ACFA01000446_gene6917	2.853e-85	298.0	COG0439@1|root,COG0439@2|Bacteria,2I8I5@201174|Actinobacteria	201174|Actinobacteria	I	Biotin carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,CPSase_L_D2
SRR21617310_k127_488287_8	467200.ACFA01000446_gene6916	1.772e-64	236.0	2DUPR@1|root,32UXI@2|Bacteria,2ICRA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_488287_11	665577.JH993790_gene2008	2.555e-39	164.0	2F307@1|root,33VVH@2|Bacteria,2IKR5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_488287_10	909613.UO65_4475	5.827e-46	181.0	COG3146@1|root,COG3146@2|Bacteria,2HWRP@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	Acetyltransf_6
SRR21617310_k127_488287_2	665577.JH993790_gene2009	2.95e-141	468.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SRR21617310_k127_488287_9	502025.Hoch_5296	1.066e-58	219.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_488287_1	1089545.KB913037_gene1343	1.225e-254	816.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4E0K4@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR21617310_k127_488617_6	675635.Psed_3661	1.908e-13	75.0	2E6IT@1|root,3315W@2|Bacteria,2GR2R@201174|Actinobacteria,4E6J5@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR21617310_k127_488617_0	222534.KB893720_gene888	1.215e-70	251.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria	201174|Actinobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR21617310_k127_488617_7	1120936.KB907213_gene4850	8.588e-12	76.0	COG0664@1|root,COG2114@1|root,COG0664@2|Bacteria,COG2114@2|Bacteria,2IBAI@201174|Actinobacteria	201174|Actinobacteria	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR21617310_k127_488617_1	1157632.AQWQ01000016_gene3291	2.258e-35	138.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR21617310_k127_488617_4	485913.Krac_4260	1.376e-22	107.0	2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi	200795|Chloroflexi	S	pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_488617_9	1463900.JOIX01000049_gene7804	0.0003641	43.0	COG3293@1|root,COG3293@2|Bacteria,2IPDX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
SRR21617310_k127_488617_8	467200.ACFA01000003_gene1697	5.206e-06	49.0	COG3293@1|root,COG3293@2|Bacteria,2IIAY@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
SRR21617310_k127_488617_2	640132.Srot_0433	3.428e-26	119.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_488617_5	1394178.AWOO02000028_gene5396	8.629e-16	85.0	2DTYE@1|root,33N7R@2|Bacteria,2GXD4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHIM
SRR21617310_k127_488617_3	469383.Cwoe_1469	8.35e-24	115.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR21617310_k127_498170_0	479432.Sros_4872	4.097e-152	491.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4EHFA@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR21617310_k127_498170_1	28444.JODQ01000007_gene5269	1.758e-105	346.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EGQ4@85012|Streptosporangiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR21617310_k127_498170_2	1329516.JPST01000001_gene950	1.187e-08	57.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,27B71@186824|Thermoactinomycetaceae	91061|Bacilli	M	Transglycosylase	pbp1B	-	2.4.1.129	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR21617310_k127_500124_3	351607.Acel_0140	7.878e-08	64.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4ESZ4@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR21617310_k127_500124_1	1463887.KL589957_gene861	4.154e-35	151.0	COG5606@1|root,COG5606@2|Bacteria,2IHT8@201174|Actinobacteria	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_500124_0	35754.JNYJ01000062_gene1481	1.935e-83	290.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4DCS2@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR21617310_k127_500124_4	1122218.KB893654_gene2462	2.605e-07	63.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,1JSDB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR21617310_k127_500124_2	714943.Mucpa_5696	1.013e-19	105.0	COG0507@1|root,COG0507@2|Bacteria,4NHCF@976|Bacteroidetes,1IQ7G@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC,Viral_helicase1
SRR21617310_k127_510678_0	196162.Noca_4441	1.364e-191	619.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2GMEE@201174|Actinobacteria,4DQJ0@85009|Propionibacteriales	201174|Actinobacteria	P	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR21617310_k127_510678_3	1380347.JNII01000009_gene2012	8.749e-111	370.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_510678_1	1120949.KB903299_gene6015	2.939e-161	521.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_510678_5	1380347.JNII01000009_gene2007	7.781e-96	325.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4EUMA@85013|Frankiales	201174|Actinobacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR21617310_k127_510678_2	1122611.KB903996_gene7507	3.142e-126	423.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EFP2@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR21617310_k127_510678_4	479435.Kfla_2024	1.243e-110	366.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DUFD@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_510678_8	1403819.BATR01000161_gene5268	3.094e-07	57.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR21617310_k127_510678_6	196162.Noca_4459	4.237e-63	228.0	COG2128@1|root,COG2128@2|Bacteria,2HZX3@201174|Actinobacteria,4DUDY@85009|Propionibacteriales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_510678_7	65497.JODV01000006_gene906	8.057e-35	134.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4DYQB@85010|Pseudonocardiales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR21617310_k127_511885_28	1370120.AUWR01000011_gene1084	9.52e-16	76.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,233XN@1762|Mycobacteriaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR21617310_k127_511885_16	351607.Acel_0305	3.484e-55	194.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4ESVR@85013|Frankiales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR21617310_k127_511885_3	298653.Franean1_6049	9.224e-97	321.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4ERGJ@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR21617310_k127_511885_12	909613.UO65_1230	4.334e-60	225.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4DXQB@85010|Pseudonocardiales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR21617310_k127_511885_23	67332.FM21_26055	6.423e-30	131.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR21617310_k127_511885_1	1123320.KB889574_gene5571	6.144e-132	430.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR21617310_k127_511885_19	1121877.JQKF01000009_gene544	2.902e-45	164.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR21617310_k127_511885_20	1394178.AWOO02000003_gene2743	1.043e-40	154.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4EJCM@85012|Streptosporangiales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR21617310_k127_511885_2	471852.Tcur_4315	3.826e-100	340.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4EHH4@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR21617310_k127_511885_9	1089455.MOPEL_098_00320	8.576e-71	241.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4F6RM@85018|Dermatophilaceae	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR21617310_k127_511885_27	457425.XNR_3737	1.15e-16	82.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR21617310_k127_511885_24	2045.KR76_21240	9.948e-30	120.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4DRI1@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR21617310_k127_511885_11	1869.MB27_32465	5.153e-65	223.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4DDMH@85008|Micromonosporales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR21617310_k127_511885_26	134676.ACPL_793	1.056e-25	109.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4DEDA@85008|Micromonosporales	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR21617310_k127_511885_6	471853.Bcav_3131	6.801e-77	261.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR21617310_k127_511885_25	675635.Psed_5416	2.836e-27	112.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4E6JP@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR21617310_k127_511885_15	561175.KB894099_gene5119	4.14e-58	207.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4EINA@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR21617310_k127_511885_7	882083.SacmaDRAFT_0708	3.703e-73	250.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DXPD@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR21617310_k127_511885_22	383372.Rcas_4010	6.963e-36	139.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi,375P7@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR21617310_k127_511885_8	477641.MODMU_4902	2.66e-72	252.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4ES1E@85013|Frankiales	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR21617310_k127_511885_29	1122179.KB890458_gene669	4.286e-15	78.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1IUA3@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR21617310_k127_511885_18	471852.Tcur_4302	1.617e-48	180.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4EIUJ@85012|Streptosporangiales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR21617310_k127_511885_0	365528.KB891252_gene5577	1.741e-168	542.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4ERNA@85013|Frankiales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR21617310_k127_511885_13	269800.Tfu_2625	6.668e-60	214.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR21617310_k127_511885_5	1120973.AQXL01000112_gene1094	3.485e-83	294.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR21617310_k127_511885_17	35754.JNYJ01000001_gene7316	1.42e-50	187.0	COG1011@1|root,COG1011@2|Bacteria,2HP89@201174|Actinobacteria,4DGIQ@85008|Micromonosporales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR21617310_k127_511885_21	351607.Acel_0329	3.491e-38	143.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4ET4N@85013|Frankiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR21617310_k127_511885_30	1403948.Q618_VCMC00003G0093	1.149e-14	73.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D6P0@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR21617310_k127_511885_14	1123320.KB889574_gene5547	3.921e-59	207.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR21617310_k127_511885_10	1123320.KB889574_gene5546	1.796e-65	225.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR21617310_k127_511885_4	1146883.BLASA_4271	4.935e-84	283.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EREE@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR21617310_k127_514163_3	67315.JOBD01000045_gene862	2.848e-05	47.0	COG1309@1|root,COG1309@2|Bacteria,2IT8G@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_514163_1	1120950.KB892796_gene2259	3.775e-62	223.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR21617310_k127_514163_2	1121272.KB903272_gene219	7.641e-58	209.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria,4DG2C@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR21617310_k127_514163_0	33876.JNXY01000015_gene7460	1.453e-67	244.0	COG0242@1|root,COG0457@1|root,COG0242@2|Bacteria,COG0457@2|Bacteria,2GJT4@201174|Actinobacteria,4DA7J@85008|Micromonosporales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,Pep_deformylase
SRR21617310_k127_514163_4	1123023.JIAI01000008_gene1260	4.269e-05	48.0	COG0739@1|root,COG0739@2|Bacteria,2HENP@201174|Actinobacteria,4E9PI@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR21617310_k127_514165_1	1172180.KB911776_gene1046	2.039e-10	64.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
SRR21617310_k127_523913_9	1003195.SCAT_2736	2.118e-09	62.0	COG4454@1|root,COG4454@2|Bacteria,2I9JP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
SRR21617310_k127_523913_8	2074.JNYD01000002_gene5610	8.232e-27	111.0	COG3462@1|root,COG3462@2|Bacteria,2GRGM@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR21617310_k127_523913_0	710696.Intca_2658	2.824e-225	716.0	2EX6H@1|root,33QHE@2|Bacteria,2I75T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_523913_6	1068978.AMETH_3740	7.811e-42	160.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_523913_3	1068978.AMETH_3741	7.952e-73	250.0	COG0500@1|root,COG2226@2|Bacteria,2II3C@201174|Actinobacteria,4E44D@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR21617310_k127_523913_10	1333523.L593_02375	0.0003087	54.0	COG3291@1|root,arCOG03509@1|root,arCOG02546@2157|Archaea,arCOG03509@2157|Archaea,2Y7ZF@28890|Euryarchaeota,24143@183963|Halobacteria	183963|Halobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR21617310_k127_523913_11	1457250.BBMO01000002_gene2838	0.0003332	54.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
SRR21617310_k127_523913_4	1380347.JNII01000006_gene1445	1.338e-70	244.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria	201174|Actinobacteria	E	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep,Hexapep_2
SRR21617310_k127_523913_5	1123023.JIAI01000007_gene1708	4.061e-63	229.0	COG1595@1|root,COG1595@2|Bacteria,2GJ21@201174|Actinobacteria,4ECPI@85010|Pseudonocardiales	201174|Actinobacteria	K	belongs to the sigma-70 factor family	sig20	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR21617310_k127_523913_2	479434.Sthe_1148	1.875e-78	276.0	COG0688@1|root,COG0688@2|Bacteria,2G9SQ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phosphatidylserine decarboxylase-related	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR21617310_k127_523913_1	479434.Sthe_1149	7.578e-172	547.0	COG3919@1|root,COG3919@2|Bacteria,2G80M@200795|Chloroflexi	200795|Chloroflexi	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_523913_7	1382356.JQMP01000001_gene989	2.986e-29	125.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi,27Z2Y@189775|Thermomicrobia	189775|Thermomicrobia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR21617310_k127_526601_1	234267.Acid_7358	1.896e-94	319.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100,4.2.1.17	ko:K01715,ko:K07537	ko00362,ko00650,ko01100,ko01120,ko01200,ko01220,map00362,map00650,map01100,map01120,map01200,map01220	M00541	R03026,R05597	RC00831,RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR21617310_k127_526601_5	35754.JNYJ01000089_gene6364	2.671e-49	190.0	COG4902@1|root,COG4902@2|Bacteria,2IKIN@201174|Actinobacteria,4DIMT@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
SRR21617310_k127_526601_4	35754.JNYJ01000089_gene6360	1.855e-50	182.0	COG0745@1|root,COG0745@2|Bacteria,2I8R2@201174|Actinobacteria,4DHJ4@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_526601_0	1116232.AHBF01000137_gene1881	4.142e-147	481.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_526601_2	1121877.JQKF01000026_gene2435	7.062e-85	286.0	COG0235@1|root,COG0235@2|Bacteria,2IC5J@201174|Actinobacteria,4CNE7@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR21617310_k127_526601_7	1210884.HG799463_gene9589	1.641e-07	56.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_526601_3	1463917.JODC01000004_gene6158	3.824e-72	244.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_526601_6	1449347.JQLN01000007_gene1826	1.932e-35	141.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,2M3BQ@2063|Kitasatospora	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR21617310_k127_528366_5	710111.FraQA3DRAFT_4808	6.635e-81	279.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4EUBH@85013|Frankiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR21617310_k127_528366_13	479432.Sros_2145	5.895e-42	160.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4EJZA@85012|Streptosporangiales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR21617310_k127_528366_11	471852.Tcur_4853	1.663e-56	203.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4EJ6E@85012|Streptosporangiales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR21617310_k127_528366_4	290397.Adeh_4323	1.736e-96	340.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,2YUK7@29|Myxococcales	28221|Deltaproteobacteria	KL	SMART helicase c2	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
SRR21617310_k127_528366_12	58123.JOFJ01000019_gene3796	1.995e-46	177.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4EGBS@85012|Streptosporangiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR21617310_k127_528366_19	1043493.BBLU01000017_gene1375	5.013e-17	81.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR21617310_k127_528366_17	1229780.BN381_100117	1.416e-24	107.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR21617310_k127_528366_7	909663.KI867150_gene1676	2.604e-76	267.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_528366_15	1313172.YM304_38190	8.013e-35	152.0	COG1030@1|root,COG1030@2|Bacteria,2IATM@201174|Actinobacteria	201174|Actinobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR21617310_k127_528366_10	211114.JOEF01000003_gene3132	3.298e-57	213.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4DYGT@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR21617310_k127_528366_3	1229203.KI301992_gene2340	1.389e-101	344.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,3UX1R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR21617310_k127_528366_23	1449353.JQMQ01000005_gene5293	7.352e-09	68.0	COG0346@1|root,COG0346@2|Bacteria,2I9G1@201174|Actinobacteria,2NIFF@228398|Streptacidiphilus	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_528366_14	56110.Oscil6304_4808	4.018e-40	160.0	COG0668@1|root,COG0668@2|Bacteria,1G1BH@1117|Cyanobacteria,1H8W6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR21617310_k127_528366_1	351607.Acel_2004	1.383e-116	407.0	COG0744@1|root,COG2815@1|root,COG0744@2|Bacteria,COG2815@2|Bacteria,2GK21@201174|Actinobacteria,4ERGQ@85013|Frankiales	201174|Actinobacteria	M	PFAM glycosyl transferase, family 51	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR21617310_k127_528366_16	1121087.AUCK01000004_gene1188	6.619e-26	112.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,1ZGGX@1386|Bacillus	91061|Bacilli	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR21617310_k127_528366_6	105422.BBPM01000067_gene397	1.561e-77	270.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,2NG04@228398|Streptacidiphilus	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR21617310_k127_528366_24	1122602.ATXP01000002_gene684	5.053e-08	65.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,1W8F5@1268|Micrococcaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR21617310_k127_528366_2	330214.NIDE4207	2.754e-114	386.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR21617310_k127_528366_0	1323361.JPOC01000002_gene4499	1.84e-149	500.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4G6DS@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR21617310_k127_528366_8	1463857.JOFZ01000005_gene3209	1.268e-69	246.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR21617310_k127_528366_9	1123023.JIAI01000002_gene5302	7.65e-64	236.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DY80@85010|Pseudonocardiales	201174|Actinobacteria	P	overlaps another CDS with the same product name	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR21617310_k127_528366_21	471852.Tcur_1708	6.871e-12	74.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,4EJMR@85012|Streptosporangiales	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_528366_20	215803.DB30_3268	9.095e-14	77.0	COG1547@1|root,COG1547@2|Bacteria,1P75K@1224|Proteobacteria,432ZJ@68525|delta/epsilon subdivisions,2WXIJ@28221|Deltaproteobacteria,2Z233@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR21617310_k127_528366_18	1123242.JH636436_gene633	3.386e-23	108.0	COG1694@1|root,COG1694@2|Bacteria,2J047@203682|Planctomycetes	203682|Planctomycetes	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR21617310_k127_528366_22	326424.FRAAL6385	4.847e-09	57.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4ESQT@85013|Frankiales	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR21617310_k127_536696_6	1206720.BAFQ01000286_gene6050	4.588e-14	82.0	COG2314@1|root,COG2314@2|Bacteria,2I47M@201174|Actinobacteria,4G2DN@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR21617310_k127_536696_7	1380763.BG53_02850	1.6e-08	65.0	COG4454@1|root,COG4454@2|Bacteria,1V23W@1239|Firmicutes,4HGGT@91061|Bacilli,2717N@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR21617310_k127_536696_3	266117.Rxyl_2941	8.898e-76	260.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
SRR21617310_k127_536696_1	1123023.JIAI01000001_gene6191	1.504e-127	430.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4E18S@85010|Pseudonocardiales	201174|Actinobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR21617310_k127_536696_2	103733.JNYO01000022_gene7011	2.153e-124	409.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DXF2@85010|Pseudonocardiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR21617310_k127_536696_0	35754.JNYJ01000022_gene8162	1.607e-205	650.0	COG0318@1|root,COG0318@2|Bacteria,2I8PR@201174|Actinobacteria,4D9XQ@85008|Micromonosporales	201174|Actinobacteria	IQ	AMP-dependent synthetase and ligase	-	-	2.7.7.97	ko:K21284	-	-	R11554	RC00043	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR21617310_k127_536696_4	1121272.KB903249_gene2292	1.836e-32	133.0	COG0236@1|root,COG0236@2|Bacteria,2GSX0@201174|Actinobacteria,4DFXZ@85008|Micromonosporales	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR21617310_k127_536696_5	1121272.KB903249_gene2310	1.401e-15	82.0	COG0236@1|root,COG0236@2|Bacteria,2GYXC@201174|Actinobacteria,4DGFC@85008|Micromonosporales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_546177_3	390989.JOEG01000014_gene3137	1.084e-74	253.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR21617310_k127_546177_4	91464.S7335_589	1.96e-35	145.0	COG0596@1|root,COG0596@2|Bacteria,1GFX0@1117|Cyanobacteria	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR21617310_k127_546177_0	33876.JNXY01000027_gene3573	4.617e-135	440.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4DBNI@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
SRR21617310_k127_546177_1	1394178.AWOO02000020_gene7439	9.469e-125	404.0	COG1794@1|root,COG1794@2|Bacteria,2H7J9@201174|Actinobacteria,4EKYH@85012|Streptosporangiales	201174|Actinobacteria	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR21617310_k127_546177_2	1157637.KB892092_gene6951	7.028e-90	310.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR21617310_k127_546177_5	1122239.AULS01000001_gene1699	2.609e-35	142.0	2DWAY@1|root,33ZCX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_546177_6	1122604.JONR01000015_gene107	7.512e-08	55.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XD55@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
SRR21617310_k127_552036_2	1463858.JOHR01000005_gene1155	2.896e-13	80.0	COG1040@1|root,COG1040@2|Bacteria,2IFV8@201174|Actinobacteria	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR21617310_k127_552036_3	208439.AJAP_42485	1.982e-12	75.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
SRR21617310_k127_552036_1	246197.MXAN_4195	2.828e-16	94.0	2DPQQ@1|root,3330I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_A2_3
SRR21617310_k127_552036_0	649831.L083_6469	1.316e-227	748.0	COG3209@1|root,COG3209@2|Bacteria,2I35N@201174|Actinobacteria,4D8JW@85008|Micromonosporales	201174|Actinobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
SRR21617310_k127_553421_14	1121468.AUBR01000036_gene1298	7.527e-65	238.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42G77@68295|Thermoanaerobacterales	186801|Clostridia	D	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_553421_6	1306174.JODP01000016_gene7134	4.377e-120	392.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_553421_24	645465.ACUR01000362_gene5390	1.732e-18	98.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR21617310_k127_553421_7	1089546.AQUI01000002_gene1621	1.107e-115	388.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,407R1@622450|Actinopolysporales	201174|Actinobacteria	J	Ribosomal protein S2	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR21617310_k127_553421_15	309799.DICTH_1077	1.163e-64	227.0	COG0264@1|root,COG0264@2|Bacteria	2|Bacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR21617310_k127_553421_10	1123322.KB904679_gene3219	3.143e-88	301.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR21617310_k127_553421_13	1048339.KB913029_gene3531	4.166e-66	239.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4ESC9@85013|Frankiales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR21617310_k127_553421_19	477641.MODMU_4396	3.472e-47	181.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4EXIS@85013|Frankiales	201174|Actinobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR21617310_k127_553421_9	326427.Cagg_0286	3.311e-92	318.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,374VF@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR21617310_k127_553421_5	1123320.KB889675_gene4036	9.7e-128	421.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR21617310_k127_553421_16	1463821.JOGR01000007_gene209	1.002e-62	242.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4EXNF@85014|Glycomycetales	201174|Actinobacteria	M	Peptidase family M50	rip1	GO:0008150,GO:0040007	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR21617310_k127_553421_4	644284.Arch_0607	4.344e-133	434.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4D394@85005|Actinomycetales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR21617310_k127_553421_20	196162.Noca_3198	1.057e-39	166.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4DP1G@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR21617310_k127_553421_1	1382306.JNIM01000001_gene1083	7.121e-260	856.0	COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR21617310_k127_553421_23	589865.DaAHT2_1882	1.696e-23	105.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria,2MKTS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR21617310_k127_553421_8	635013.TherJR_1374	1.225e-115	384.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,2604E@186807|Peptococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR21617310_k127_553421_27	1303518.CCALI_01341	1.97e-15	80.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
SRR21617310_k127_553421_2	469371.Tbis_1061	8.201e-224	729.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4DXNY@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR21617310_k127_553421_28	234267.Acid_5182	1.49e-13	76.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR21617310_k127_553421_25	1123065.ATWL01000002_gene1695	1.281e-16	85.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR21617310_k127_553421_11	479432.Sros_2119	1.229e-81	286.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4EHHU@85012|Streptosporangiales	201174|Actinobacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR21617310_k127_553421_17	369723.Strop_1378	1.81e-62	237.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4D96B@85008|Micromonosporales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR21617310_k127_553421_12	675635.Psed_4666	4.019e-71	262.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DZQA@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR21617310_k127_553421_21	269800.Tfu_0783	5.513e-34	134.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4EK2G@85012|Streptosporangiales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR21617310_k127_553421_0	1236902.ANAS01000025_gene372	9.627e-273	861.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4EFGY@85012|Streptosporangiales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR21617310_k127_553421_3	1048339.KB913029_gene3572	7.119e-153	495.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4ERHK@85013|Frankiales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR21617310_k127_553421_22	1121272.KB903290_gene4484	9.662e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DEWR@85008|Micromonosporales	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR21617310_k127_553421_26	35754.JNYJ01000008_gene3290	1.298e-15	85.0	COG3393@1|root,COG3393@2|Bacteria,2IF2P@201174|Actinobacteria,4D8RE@85008|Micromonosporales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR21617310_k127_553421_18	1380394.JADL01000001_gene3101	4.647e-54	205.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2JV5D@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
SRR21617310_k127_555156_1	1209984.BN978_01198	2.484e-76	276.0	COG4974@1|root,COG4974@2|Bacteria,2GNKJ@201174|Actinobacteria,2369G@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_555156_2	1209984.BN978_01197	7.946e-34	136.0	COG3655@1|root,COG3655@2|Bacteria,2IQQJ@201174|Actinobacteria,239IQ@1762|Mycobacteriaceae	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
SRR21617310_k127_555156_0	1209984.BN978_01196	7.833e-158	504.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,233YE@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_565390_3	390989.JOEG01000034_gene1656	2.782e-47	188.0	2EZP6@1|root,33SU7@2|Bacteria,2GP88@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_565390_4	1120948.KB903244_gene3080	8.271e-47	174.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,4E3D5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR21617310_k127_565390_0	269800.Tfu_2554	7.75e-279	884.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4EHTY@85012|Streptosporangiales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR21617310_k127_565390_1	1313172.YM304_06050	4.768e-160	516.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CMTT@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Fumarate hydratase class II	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR21617310_k127_565390_2	391037.Sare_4756	1.294e-57	215.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4DA7U@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR21617310_k127_566899_2	906888.JCM19314_2292	1.808e-05	52.0	COG0745@1|root,COG0745@2|Bacteria,4NP5C@976|Bacteroidetes,1I24M@117743|Flavobacteriia,3HKBK@363408|Nonlabens	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR21617310_k127_566899_0	1136417.AZWE01000051_gene3902	5.086e-262	845.0	COG1020@1|root,COG1020@2|Bacteria,2GM1X@201174|Actinobacteria,4D9KM@85008|Micromonosporales	201174|Actinobacteria	Q	Lantibiotic dehydratase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Lant_dehydr_N,NAD_binding_4,PP-binding
SRR21617310_k127_566899_1	483219.LILAB_26235	1.132e-57	209.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR21617310_k127_571063_5	494419.ALPM01000060_gene2026	0.0001485	45.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,1WC7A@1268|Micrococcaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR21617310_k127_571063_4	28444.JODQ01000005_gene1244	5.044e-09	58.0	29VWA@1|root,30HE5@2|Bacteria,2GY2J@201174|Actinobacteria,4EKZ0@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_571063_3	909613.UO65_4599	5.087e-36	140.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4E3PI@85010|Pseudonocardiales	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR21617310_k127_571063_1	1033736.CAHK01000007_gene2376	3.773e-74	255.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4F9NT@85019|Brevibacteriaceae	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR21617310_k127_571063_0	1122611.KB903941_gene2169	2.389e-165	533.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EH24@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR21617310_k127_571063_2	1089552.KI911559_gene3640	1.012e-44	184.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2JQWX@204441|Rhodospirillales	204441|Rhodospirillales	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR21617310_k127_574037_1	1236902.ANAS01000012_gene650	4.55e-157	510.0	COG0419@1|root,COG0419@2|Bacteria,2I4EM@201174|Actinobacteria	201174|Actinobacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR21617310_k127_574037_3	298653.Franean1_3974	8.898e-99	338.0	COG4924@1|root,COG4924@2|Bacteria,2GNHY@201174|Actinobacteria,4EW01@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
SRR21617310_k127_574037_2	1429046.RR21198_4923	3.676e-150	488.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR21617310_k127_574037_4	1121877.JQKF01000006_gene924	2.458e-39	149.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_574037_0	298653.Franean1_3066	2.935e-243	759.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR21617310_k127_575508_4	591167.Sfla_6521	2.87e-43	159.0	COG4974@1|root,COG4974@2|Bacteria,2IGPB@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_575508_5	591167.Sfla_6522	2.48e-38	152.0	COG0582@1|root,COG0582@2|Bacteria,2GNX4@201174|Actinobacteria	201174|Actinobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_575508_1	591167.Sfla_6522	1.722e-156	501.0	COG0582@1|root,COG0582@2|Bacteria,2GNX4@201174|Actinobacteria	201174|Actinobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_575508_2	1463887.KL590066_gene2655	1.062e-67	234.0	COG2453@1|root,COG2453@2|Bacteria,2IK44@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
SRR21617310_k127_575508_7	1156844.KB891828_gene805	5.015e-14	76.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
SRR21617310_k127_575508_3	2002.JOEQ01000100_gene6120	1.446e-60	214.0	COG3464@1|root,COG3464@2|Bacteria,2HU54@201174|Actinobacteria,4EIZ7@85012|Streptosporangiales	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
SRR21617310_k127_575508_8	935840.JAEQ01000037_gene3684	1.3e-12	70.0	COG4916@1|root,COG4916@2|Bacteria,1MXWM@1224|Proteobacteria,2VEZW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR21617310_k127_575508_6	585543.HMPREF0969_00228	3.652e-19	91.0	COG1262@1|root,COG1262@2|Bacteria,4PA78@976|Bacteroidetes,2FYVU@200643|Bacteroidia,4AUDG@815|Bacteroidaceae	976|Bacteroidetes	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR21617310_k127_575508_0	525909.Afer_1025	0.0	1214.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR21617310_k127_57862_1	1120934.KB894409_gene6437	9.205e-28	117.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DXKC@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_57862_4	1382303.JPOM01000001_gene2283	0.0005068	49.0	COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2UFK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR21617310_k127_57862_3	109760.SPPG_00373T0	9.994e-15	87.0	2BSCV@1|root,2S1YD@2759|Eukaryota,39KTS@33154|Opisthokonta,3Q570@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_57862_2	450851.PHZ_c0812	1.663e-17	94.0	COG3794@1|root,COG3794@2|Bacteria,1QWIK@1224|Proteobacteria,2TWY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR21617310_k127_57862_0	1394178.AWOO02000098_gene8149	1.71e-101	352.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR21617310_k127_578800_0	644284.Arch_1678	3.553e-20	102.0	COG4974@1|root,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4D5Z6@85005|Actinomycetales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
SRR21617310_k127_578800_2	33035.JPJF01000072_gene4385	9.652e-06	51.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HD_4,HTH_3
SRR21617310_k127_585570_16	401526.TcarDRAFT_0740	5.322e-35	145.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4H4P0@909932|Negativicutes	909932|Negativicutes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR21617310_k127_585570_14	1125863.JAFN01000001_gene2863	2.053e-66	239.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR21617310_k127_585570_13	351607.Acel_2054	9.674e-74	264.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4ESE4@85013|Frankiales	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR21617310_k127_585570_2	1157635.KB892035_gene6376	1.461e-157	520.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR21617310_k127_585570_8	285535.JOEY01000008_gene8801	5.955e-99	331.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR21617310_k127_585570_17	266117.Rxyl_1544	6.8e-35	155.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CR5S@84995|Rubrobacteria	84995|Rubrobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR21617310_k127_585570_18	869210.Marky_0355	1.436e-33	151.0	COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
SRR21617310_k127_585570_19	28444.JODQ01000007_gene5664	4.789e-28	131.0	COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria,4EQQY@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_585570_4	500153.JOEK01000021_gene28	1.175e-122	404.0	COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_585570_5	469383.Cwoe_4743	3.157e-119	393.0	COG0119@1|root,COG0119@2|Bacteria,2GJBI@201174|Actinobacteria,4CRBE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
SRR21617310_k127_585570_7	1235279.C772_01747	3.532e-100	351.0	COG4569@1|root,COG4569@2|Bacteria,1TQJS@1239|Firmicutes,4HCRZ@91061|Bacilli,26DRA@186818|Planococcaceae	91061|Bacilli	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	mhpF	-	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
SRR21617310_k127_585570_12	1121033.AUCF01000033_gene3610	8.414e-77	277.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2U0JG@28211|Alphaproteobacteria,2JW72@204441|Rhodospirillales	204441|Rhodospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR21617310_k127_585570_9	311403.Arad_7264	3.552e-93	319.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TUWC@28211|Alphaproteobacteria,4BAZA@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	2-oxohepta-3-ene-1,7-dioic acid hydratase	xylJ	-	4.2.1.80	ko:K02509,ko:K02554	ko00350,ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00350,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04132,R04781,R06897	RC00750,RC01213,RC01615,RC02595	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
SRR21617310_k127_585570_15	485913.Krac_2886	1.047e-35	156.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR21617310_k127_585570_3	1079986.JH164864_gene6613	1.789e-153	511.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR21617310_k127_585570_10	1123023.JIAI01000001_gene7771	2.695e-91	311.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	-	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR21617310_k127_585570_1	543632.JOJL01000020_gene629	5.258e-199	639.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR21617310_k127_585570_6	485913.Krac_9361	5.509e-107	355.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR21617310_k127_585570_0	1122182.KB903814_gene3038	4.588e-205	651.0	COG0477@1|root,COG0477@2|Bacteria,2HEI5@201174|Actinobacteria,4DB6U@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_585570_20	756883.Halar_1739	6.265e-09	68.0	COG0697@1|root,arCOG00272@2157|Archaea	2157|Archaea	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR21617310_k127_585570_11	1123023.JIAI01000004_gene7867	2.711e-89	301.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DZ0W@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR21617310_k127_600206_6	1298863.AUEP01000010_gene4390	1.008e-57	205.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4DQBM@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR21617310_k127_600206_1	1120936.KB907219_gene3201	2.105e-153	497.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_600206_3	67373.JOBF01000009_gene3153	9.927e-127	417.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	oppD1	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_600206_7	869210.Marky_1369	9.679e-47	187.0	COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR21617310_k127_600206_5	869210.Marky_1368	7.243e-63	234.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR21617310_k127_600206_11	479434.Sthe_2568	3.571e-23	104.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR21617310_k127_600206_2	869210.Marky_1366	2.744e-139	448.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR21617310_k127_600206_8	649638.Trad_1144	4.757e-44	167.0	COG1309@1|root,COG1309@2|Bacteria,1WI7P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
SRR21617310_k127_600206_15	502025.Hoch_0529	5.028e-12	68.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR21617310_k127_600206_4	321332.CYB_0991	2.564e-64	228.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1GYMC@1129|Synechococcus	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR21617310_k127_600206_14	196162.Noca_1129	2.715e-13	77.0	2DP8R@1|root,32UKH@2|Bacteria	2|Bacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_600206_13	1380393.JHVP01000014_gene4755	3.486e-16	92.0	COG2755@1|root,COG2755@2|Bacteria,2GMVS@201174|Actinobacteria,4ESHM@85013|Frankiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR21617310_k127_600206_12	1395516.PMO01_12370	6.488e-20	105.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_600206_16	1187851.A33M_2855	7.169e-06	55.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,2TTX7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR21617310_k127_600206_9	1121926.AXWO01000007_gene163	3.73e-28	132.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
SRR21617310_k127_600206_10	485913.Krac_7871	1.177e-23	114.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_600206_0	479434.Sthe_3293	3.585e-200	635.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR21617310_k127_604208_1	365528.KB891159_gene5350	3.189e-110	366.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4ES8Q@85013|Frankiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_604208_0	446470.Snas_1978	1.44e-192	611.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EZWJ@85014|Glycomycetales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR21617310_k127_618214_8	222534.KB893739_gene1494	2.472e-26	113.0	2DSW3@1|root,33HNJ@2|Bacteria,2I802@201174|Actinobacteria,4ETJE@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR21617310_k127_618214_6	859657.RPSI07_mp1539	7.737e-33	142.0	2E7D8@1|root,331WD@2|Bacteria,1NEZT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_618214_11	356851.JOAN01000001_gene3824	6.8e-07	58.0	2DTMJ@1|root,33KXN@2|Bacteria,2ITE7@201174|Actinobacteria,4DFGS@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_618214_0	561175.KB894097_gene288	1.26e-138	451.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4EGUG@85012|Streptosporangiales	201174|Actinobacteria	E	Helix-hairpin-helix domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR21617310_k127_618214_5	1122939.ATUD01000004_gene3816	4.201e-42	169.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR21617310_k127_618214_10	463191.SSEG_05971	9.196e-15	87.0	COG1357@1|root,COG1357@2|Bacteria,2GJI4@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_618214_2	1120950.KB892760_gene5744	5.149e-109	367.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4DQ3A@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR21617310_k127_618214_1	479434.Sthe_3124	5.294e-122	402.0	COG0580@1|root,COG0580@2|Bacteria,2GBTV@200795|Chloroflexi,27YNB@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
SRR21617310_k127_618214_7	1306174.JODP01000001_gene5160	1.181e-30	135.0	COG3877@1|root,COG3877@2|Bacteria,2IT3M@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR21617310_k127_618214_4	1229780.BN381_80366	3.844e-88	319.0	COG4677@1|root,COG4677@2|Bacteria,2I7VB@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR21617310_k127_618214_3	243090.RB12344	3.58e-102	347.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
SRR21617310_k127_618214_9	1240349.ANGC01000052_gene4130	1.995e-19	101.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4FXDK@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_628400_17	196162.Noca_2193	3.544e-37	143.0	2CRSQ@1|root,32SPK@2|Bacteria,2IQ50@201174|Actinobacteria,4DS85@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR21617310_k127_628400_9	66875.JODY01000026_gene2797	2.438e-86	293.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_628400_19	1120949.KB903328_gene8887	2.628e-14	76.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8SS@85008|Micromonosporales	201174|Actinobacteria	V	resistance ABC transporter ATPase subunit	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
SRR21617310_k127_628400_13	1120950.KB892774_gene1259	2.189e-56	209.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DPYQ@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR21617310_k127_628400_18	1463825.JNXC01000001_gene6240	1.101e-16	95.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXC3@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_628400_6	1123320.KB889697_gene9060	2.811e-109	387.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR21617310_k127_628400_21	1449976.KALB_2142	9.817e-06	54.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E0NW@85010|Pseudonocardiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_628400_11	882086.SacxiDRAFT_2206	8.19e-78	264.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	ybhB	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR21617310_k127_628400_12	106370.Francci3_0805	1.273e-73	254.0	COG2514@1|root,COG2514@2|Bacteria,2GUZK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR21617310_k127_628400_10	1464048.JNZS01000002_gene346	1.353e-84	292.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DD9T@85008|Micromonosporales	201174|Actinobacteria	K	a CheY-like receiver domain and	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_628400_20	65497.JODV01000001_gene3928	2.204e-07	58.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DZF1@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
SRR21617310_k127_628400_14	479431.Namu_3002	1.865e-49	183.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4ET32@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_628400_8	471853.Bcav_0230	1.887e-87	301.0	COG0500@1|root,COG0500@2|Bacteria,2IGTT@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_628400_1	882083.SacmaDRAFT_1821	1.868e-175	597.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4DXGA@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_628400_15	211114.JOEF01000059_gene2714	2.363e-45	176.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4E7BJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_628400_5	469383.Cwoe_5341	2.133e-125	414.0	COG1940@1|root,COG3888@1|root,COG1940@2|Bacteria,COG3888@2|Bacteria,2GJ2S@201174|Actinobacteria,4CSEI@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,ROK
SRR21617310_k127_628400_4	1380390.JIAT01000016_gene5580	1.67e-137	453.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CP9G@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR21617310_k127_628400_7	1242864.D187_007189	5.939e-89	302.0	COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,42R26@68525|delta/epsilon subdivisions,2WN48@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR21617310_k127_628400_2	215803.DB30_8111	9.86e-155	511.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,437XM@68525|delta/epsilon subdivisions,2X9RD@28221|Deltaproteobacteria,2YUQ7@29|Myxococcales	28221|Deltaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR21617310_k127_628400_0	1463825.JNXC01000012_gene1907	3.155e-179	569.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DZGD@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_628400_16	1463825.JNXC01000012_gene1908	8.723e-40	160.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,4E5ET@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_628400_3	118173.KB235914_gene3255	2.05e-152	490.0	COG0667@1|root,COG0667@2|Bacteria,1G2QT@1117|Cyanobacteria,1H9NI@1150|Oscillatoriales	1117|Cyanobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR21617310_k127_638835_0	1089546.AQUI01000002_gene4198	7.015e-202	658.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,407HV@622450|Actinopolysporales	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR21617310_k127_638835_5	1246995.AFR_17200	8.299e-33	137.0	2EGD2@1|root,33A4V@2|Bacteria,2IT2B@201174|Actinobacteria,4DEY9@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR21617310_k127_638835_6	1382306.JNIM01000001_gene3910	1.699e-14	85.0	COG4818@1|root,COG4818@2|Bacteria,2G9D6@200795|Chloroflexi	200795|Chloroflexi	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SRR21617310_k127_638835_4	1120949.KB903297_gene5448	3.659e-42	165.0	COG1714@1|root,COG1714@2|Bacteria,2HGSH@201174|Actinobacteria,4DJ2H@85008|Micromonosporales	201174|Actinobacteria	S	RDD family	pra	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RDD
SRR21617310_k127_638835_2	1283299.AUKG01000001_gene2191	2.034e-108	364.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR21617310_k127_638835_1	298654.FraEuI1c_6161	6.654e-126	413.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4ES6Z@85013|Frankiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR21617310_k127_638835_3	649831.L083_1046	1.224e-60	214.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4DDD4@85008|Micromonosporales	201174|Actinobacteria	I	B12 binding domain	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR21617310_k127_640718_3	570268.ANBB01000055_gene4873	3.333e-24	102.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4EK3Q@85012|Streptosporangiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_640718_2	935866.JAER01000007_gene393	4.602e-25	106.0	COG2026@1|root,COG2026@2|Bacteria,2IRES@201174|Actinobacteria,4DVZ9@85009|Propionibacteriales	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR21617310_k127_640718_4	935866.JAER01000007_gene395	6.101e-12	72.0	COG2161@1|root,COG2161@2|Bacteria,2IRS2@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR21617310_k127_640718_0	1283283.ATXA01000009_gene3255	0.0	1341.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR21617310_k127_640718_1	1463853.JOHW01000021_gene6890	9.827e-80	269.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR21617310_k127_645329_1	2074.JNYD01000013_gene6899	4.158e-11	72.0	2BGK0@1|root,32AID@2|Bacteria,2GQ1A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
SRR21617310_k127_645329_0	937777.Deipe_0466	7.274e-49	189.0	COG3941@1|root,COG3941@2|Bacteria	2|Bacteria	O	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR21617310_k127_647601_0	1285583.CCASEI_11755	7.108e-26	119.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria,22Q4M@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
SRR21617310_k127_647601_1	222534.KB893723_gene610	1.209e-10	74.0	291ID@1|root,2ZP4W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_647601_2	1214101.BN159_4751	3.015e-08	64.0	2DS0G@1|root,33DYY@2|Bacteria,2GKA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_651709_3	1197706.AKKK01000011_gene414	3.025e-18	93.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria,1WACD@1268|Micrococcaceae	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR21617310_k127_651709_0	1122182.KB903816_gene1615	0.0	1075.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D92W@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
SRR21617310_k127_651709_4	1121924.ATWH01000006_gene1892	2.919e-16	84.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4FQ1A@85023|Microbacteriaceae	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR21617310_k127_651709_1	298655.KI912266_gene4753	2.907e-114	379.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_651709_2	414996.IL38_15895	6.198e-59	221.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR21617310_k127_652833_2	765420.OSCT_0512	6.408e-62	221.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi,37737@32061|Chloroflexia	32061|Chloroflexia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR21617310_k127_652833_3	926569.ANT_04570	3.016e-37	150.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR21617310_k127_652833_1	357808.RoseRS_0006	1.245e-76	267.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRR21617310_k127_652833_0	351607.Acel_1116	1.217e-131	441.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4ESRC@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_657130_1	1476876.JOJO01000005_gene5295	1.011e-165	527.0	COG2175@1|root,COG2175@2|Bacteria,2HE90@201174|Actinobacteria	201174|Actinobacteria	Q	taurine catabolism dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR21617310_k127_657130_0	1476876.JOJO01000005_gene5294	0.0	1113.0	COG1020@1|root,COG3208@1|root,COG1020@2|Bacteria,COG3208@2|Bacteria	2|Bacteria	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR21617310_k127_657130_2	748280.NH8B_2509	1.048e-129	416.0	COG0110@1|root,COG0110@2|Bacteria,1QYE2@1224|Proteobacteria,2WHE2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR21617310_k127_660533_3	644966.Tmar_0011	6.507e-23	109.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WDK0@538999|Clostridiales incertae sedis	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_660533_2	365528.KB891260_gene499	1.515e-59	214.0	COG3339@1|root,COG3339@2|Bacteria,2IMCR@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR21617310_k127_660533_0	1120950.KB892757_gene6479	5.072e-66	232.0	2DUFH@1|root,33QEM@2|Bacteria,2IFQ0@201174|Actinobacteria,4DV5A@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_660533_1	1206744.BAGL01000058_gene2020	4.005e-62	218.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria,4G3D8@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR21617310_k127_665640_2	1027292.HMPREF9372_2164	1.654e-07	61.0	COG4758@1|root,COG4758@2|Bacteria,1V9SU@1239|Firmicutes,4HJWC@91061|Bacilli	91061|Bacilli	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
SRR21617310_k127_665640_0	58123.JOFJ01000003_gene2300	2.236e-52	193.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4EJ0C@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR21617310_k127_665640_1	1246445.ANAY01000001_gene362	3.248e-39	159.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4EFYY@85012|Streptosporangiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR21617310_k127_672435_8	405948.SACE_5300	1.66e-14	78.0	COG0596@1|root,COG0596@2|Bacteria,2IFY9@201174|Actinobacteria,4E2WJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_672435_11	67257.JODR01000030_gene2443	2.912e-13	76.0	COG0596@1|root,COG0596@2|Bacteria,2IFY9@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR21617310_k127_672435_5	1463900.JOIX01000057_gene3147	1.252e-26	115.0	COG0454@1|root,COG0456@2|Bacteria,2IIFA@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR21617310_k127_672435_3	1120949.KB903294_gene4396	2.997e-33	139.0	2CEIY@1|root,348HS@2|Bacteria,2H8Z7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR21617310_k127_672435_12	1429046.RR21198_1694	4.174e-12	72.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4G8ND@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR21617310_k127_672435_9	1122182.KB903825_gene467	2.009e-14	77.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR21617310_k127_672435_17	298655.KI912266_gene4800	0.0001157	47.0	COG3316@1|root,COG3316@2|Bacteria,2IS60@201174|Actinobacteria	201174|Actinobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_672435_10	1211777.BN77_p280006	1.394e-13	79.0	COG4424@1|root,COG4424@2|Bacteria,1PU7G@1224|Proteobacteria,2V5ZG@28211|Alphaproteobacteria,4BE4S@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR21617310_k127_672435_1	479432.Sros_3432	9.619e-36	151.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_672435_15	497321.C664_03250	1.092e-08	58.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,2VX9H@28216|Betaproteobacteria,2KZBG@206389|Rhodocyclales	206389|Rhodocyclales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR21617310_k127_672435_14	1463858.JOHR01000005_gene1155	1.707e-09	64.0	COG1040@1|root,COG1040@2|Bacteria,2IFV8@201174|Actinobacteria	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR21617310_k127_672435_0	543632.JOJL01000007_gene5421	4.26e-41	155.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR21617310_k127_672435_6	1304865.JAGF01000001_gene3346	3.161e-21	102.0	2FJ9I@1|root,34AZJ@2|Bacteria,2GTC9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR21617310_k127_672435_16	1304865.JAGF01000001_gene3347	1.907e-08	64.0	2CKJF@1|root,2ZEH4@2|Bacteria,2GQSN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_672435_2	797209.ZOD2009_14366	3.402e-35	148.0	COG1748@1|root,arCOG00243@2157|Archaea	2157|Archaea	E	Saccharopine dehydrogenase	-	-	1.4.1.18,1.5.1.7	ko:K00290,ko:K19064	ko00300,ko00310,ko00960,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map00960,map01100,map01110,map01130,map01230	M00030,M00032	R00446,R00715,R02317	RC00062,RC00217,RC00694,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR21617310_k127_672435_13	247156.PNF1_830	3.156e-10	66.0	COG2020@1|root,COG2020@2|Bacteria,2IE57@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR21617310_k127_672435_4	591159.ACEZ01000226_gene1252	6.967e-33	132.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR21617310_k127_672977_1	867903.ThesuDRAFT_01087	1.985e-198	627.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes	1239|Firmicutes	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR21617310_k127_672977_2	644283.Micau_1551	4.126e-192	613.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4D8YX@85008|Micromonosporales	201174|Actinobacteria	C	Malate dehydrogenase	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR21617310_k127_672977_5	1229780.BN381_10252	1.061e-101	356.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,3UX9P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR21617310_k127_672977_8	298653.Franean1_1381	1.217e-66	251.0	COG3505@1|root,COG3505@2|Bacteria,2ISKK@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
SRR21617310_k127_672977_10	1380370.JIBA01000012_gene3916	1.785e-60	236.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4FEPS@85021|Intrasporangiaceae	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_672977_11	861299.J421_3317	1.048e-37	164.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR21617310_k127_672977_6	365528.KB891230_gene2000	7.371e-94	326.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria,4ET84@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
SRR21617310_k127_672977_15	1463841.JOIR01000011_gene2705	2.13e-08	67.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_672977_13	105425.BBPL01000010_gene2161	4.263e-20	100.0	2DS0G@1|root,33DYY@2|Bacteria,2GKA4@201174|Actinobacteria,2NENR@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_672977_14	525909.Afer_0202	7.5e-17	84.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_672977_4	1123024.AUII01000003_gene3424	4.291e-102	346.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4DXEP@85010|Pseudonocardiales	201174|Actinobacteria	D	ATPase involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
SRR21617310_k127_672977_7	1394178.AWOO02000006_gene3475	3.687e-71	253.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,4EPPC@85012|Streptosporangiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT,SLT_2
SRR21617310_k127_672977_0	1380390.JIAT01000009_gene906	1.052e-256	818.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
SRR21617310_k127_672977_12	298655.KI912266_gene83	6.194e-23	101.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR21617310_k127_672977_9	1068980.ARVW01000001_gene2251	2.552e-64	226.0	COG2318@1|root,COG2318@2|Bacteria,2IGJQ@201174|Actinobacteria,4E0R8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_672977_3	429009.Adeg_0107	6.816e-130	431.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_678358_1	446470.Snas_6269	1.34e-07	60.0	COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR21617310_k127_678358_2	1169152.AXVD01000001_gene2634	3.329e-05	51.0	295Z2@1|root,2ZT9V@2|Bacteria,2H0ME@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR21617310_k127_678358_0	680198.SCAB_48301	3.504e-21	104.0	COG1403@1|root,COG1403@2|Bacteria,2GXG1@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR21617310_k127_688488_0	1906.SFRA_28340	1.174e-149	494.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR21617310_k127_688488_3	65497.JODV01000002_gene4120	7.325e-70	246.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DYII@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR21617310_k127_688488_1	525909.Afer_1266	1.458e-82	282.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR21617310_k127_688488_5	1174684.EBMC1_13536	2.362e-21	101.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria,2K68J@204457|Sphingomonadales	204457|Sphingomonadales	E	Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_688488_2	485913.Krac_3055	1.524e-80	283.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi	200795|Chloroflexi	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR21617310_k127_688488_4	485913.Krac_2051	1.659e-37	159.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi	200795|Chloroflexi	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
SRR21617310_k127_693345_1	401053.AciPR4_1449	2.199e-46	175.0	COG1695@1|root,COG1695@2|Bacteria,3Y52Q@57723|Acidobacteria,2JMZJ@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR21617310_k127_693345_0	1229780.BN381_640005	2.264e-65	237.0	29GCA@1|root,303A5@2|Bacteria,2H1W0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_693345_2	177437.HRM2_20250	7.649e-30	134.0	29GCA@1|root,303A5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_699278_5	35754.JNYJ01000021_gene388	3.704e-35	135.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DETT@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_699278_4	1121272.KB903251_gene742	5.379e-41	153.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4DF48@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_699278_1	1240349.ANGC01000015_gene669	1.195e-64	222.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria,4G2SZ@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_699278_3	1211815.CBYP010000022_gene2890	1.891e-45	180.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4EU35@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_699278_0	1380356.JNIK01000006_gene1422	6.291e-72	251.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR21617310_k127_699278_2	477641.MODMU_0850	3.134e-64	248.0	COG0577@1|root,COG0577@2|Bacteria,2IE56@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR21617310_k127_699278_6	298653.Franean1_3831	1.546e-34	138.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR21617310_k127_700105_0	29306.JOBE01000031_gene878	1.394e-30	130.0	COG1403@1|root,COG1403@2|Bacteria,2INZ4@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_700105_1	330084.JNYZ01000003_gene2311	8.548e-24	107.0	2A910@1|root,30Y4Y@2|Bacteria,2HB9H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_700105_3	1896.JOAU01000028_gene3232	1.479e-05	50.0	2BP05@1|root,32HQF@2|Bacteria,2H5JI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_704608_9	196162.Noca_4842	1.089e-16	81.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4DWSS@85009|Propionibacteriales	201174|Actinobacteria	I	PFAM coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR21617310_k127_704608_4	196162.Noca_4843	2.553e-128	419.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR21617310_k127_704608_2	196162.Noca_4844	1.892e-205	664.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DUGU@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR21617310_k127_704608_0	196162.Noca_4810	1.716e-210	658.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR21617310_k127_704608_5	931627.MycrhDRAFT_6199	3.825e-96	326.0	2DB9W@1|root,2Z7Z9@2|Bacteria,2GNW4@201174|Actinobacteria,237Y6@1762|Mycobacteriaceae	201174|Actinobacteria	S	PFAM Methane phenol toluene hydroxylase	-	-	1.14.13.25,1.14.13.69	ko:K16158,ko:K22354	ko00625,ko00680,ko01100,ko01120,ko01200,ko01220,map00625,map00680,map01100,map01120,map01200,map01220	M00174	R01142,R05444,R11901	RC00173,RC01383	ko00000,ko00001,ko00002,ko01000	-	-	-	Phenol_Hydrox
SRR21617310_k127_704608_8	196162.Noca_4808	2.044e-32	130.0	29J9R@1|root,30677@2|Bacteria,2IRTX@201174|Actinobacteria	201174|Actinobacteria	Q	MmoB DmpM	-	-	-	ko:K22355	ko00625,ko01100,ko01120,map00625,map01100,map01120	-	R05444,R11901	RC01383	ko00000,ko00001	-	-	-	MmoB_DmpM
SRR21617310_k127_704608_1	710685.MycrhN_2953	2.458e-208	662.0	COG3350@1|root,COG3350@2|Bacteria,2HEAT@201174|Actinobacteria,234I0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Methane phenol toluene hydroxylase	-	-	1.14.13.69	ko:K22353	ko00625,ko01100,ko01120,map00625,map01100,map01120	-	R05444,R11901	RC01383	ko00000,ko00001,ko01000	-	-	-	Phenol_Hydrox
SRR21617310_k127_704608_6	196162.Noca_4806	4.996e-96	325.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,2I3N3@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K22356	ko00625,ko01100,ko01120,map00625,map01100,map01120	-	R05444,R11901	RC01383	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR21617310_k127_704608_7	1068978.AMETH_4752	5.529e-71	257.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria,4DZAM@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR21617310_k127_704608_3	710685.MycrhN_2907	1.729e-162	522.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,23CB7@1762|Mycobacteriaceae	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR21617310_k127_70517_3	1429046.RR21198_2648	1.906e-92	304.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4FZI8@85025|Nocardiaceae	201174|Actinobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR21617310_k127_70517_7	479434.Sthe_1910	7.544e-19	97.0	COG5486@1|root,COG5486@2|Bacteria,2GA4T@200795|Chloroflexi,27Z8S@189775|Thermomicrobia	189775|Thermomicrobia	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR21617310_k127_70517_5	266117.Rxyl_2065	1.768e-85	293.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR21617310_k127_70517_6	1172181.KB911738_gene1956	2.154e-56	207.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR21617310_k127_70517_4	526225.Gobs_0259	3.561e-86	301.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_70517_0	1123023.JIAI01000010_gene8666	7.108e-117	392.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DYWA@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_70517_2	438753.AZC_3212	4.11e-100	343.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,3F0R2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR21617310_k127_70517_1	1218084.BBJK01000142_gene7366	3.477e-103	346.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2W9DD@28216|Betaproteobacteria,1K59C@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR21617310_k127_70517_8	42565.FP66_05005	2.159e-09	66.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria,1XI9H@135619|Oceanospirillales	135619|Oceanospirillales	NT	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,NIT
SRR21617310_k127_706923_1	222534.KB893755_gene4259	3.145e-45	167.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4ERIG@85013|Frankiales	201174|Actinobacteria	L	PFAM Transposase, Mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR21617310_k127_706923_0	1122138.AQUZ01000002_gene2132	0.0	1389.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
SRR21617310_k127_706969_3	68223.JNZY01000039_gene4515	3.504e-33	139.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR21617310_k127_706969_1	471852.Tcur_4430	8.654e-61	230.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4EHWN@85012|Streptosporangiales	201174|Actinobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR21617310_k127_706969_0	1033730.CAHG01000005_gene891	2.551e-91	319.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DN12@85009|Propionibacteriales	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR21617310_k127_706969_2	656024.FsymDg_4031	3.056e-33	134.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR21617310_k127_716395_0	335543.Sfum_3112	9.487e-127	422.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR21617310_k127_716395_1	215803.DB30_8307	1.989e-52	204.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
SRR21617310_k127_720278_2	68219.JNXI01000003_gene4907	7.678e-22	101.0	2EJ1U@1|root,33CT0@2|Bacteria,2GZFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_720278_0	1123024.AUII01000012_gene4177	5.54e-171	555.0	COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria,4E2Y5@85010|Pseudonocardiales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR21617310_k127_720278_1	266940.Krad_1724	8.959e-29	126.0	2EIV5@1|root,33CKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_723073_8	365528.KB891144_gene209	6.807e-07	54.0	COG0758@1|root,COG0758@2|Bacteria,2IFTH@201174|Actinobacteria	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR21617310_k127_723073_2	469383.Cwoe_3624	4.461e-75	279.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR21617310_k127_723073_4	1380390.JIAT01000015_gene5825	4.861e-30	122.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR21617310_k127_723073_1	1121272.KB903249_gene1239	7.601e-106	364.0	COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria,2IDQA@201174|Actinobacteria,4DBCS@85008|Micromonosporales	201174|Actinobacteria	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,P_proprotein,Peptidase_M4,Peptidase_M4_C
SRR21617310_k127_723073_7	390989.JOEG01000001_gene5238	1.841e-09	68.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4DIYB@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
SRR21617310_k127_723073_6	1907.SGLAU_08690	1.619e-22	104.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR21617310_k127_723073_5	211114.JOEF01000013_gene5024	9.097e-28	116.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4E6IW@85010|Pseudonocardiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR21617310_k127_723073_0	1160718.SU9_27504	4.52e-206	653.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_723073_3	1068980.ARVW01000001_gene7482	3.763e-52	191.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4E51J@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_723644_5	222534.KB893723_gene582	5.057e-05	48.0	COG3583@1|root,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	iga	GO:0005575,GO:0005618,GO:0005623,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.24.13	ko:K01390,ko:K08643,ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	FIVAR,G5,Gram_pos_anchor,Peptidase_M26_C,Peptidase_M26_N,YSIRK_signal
SRR21617310_k127_723644_4	1122138.AQUZ01000052_gene8379	4.516e-05	48.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_723644_0	543632.JOJL01000119_gene275	4.231e-57	201.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR21617310_k127_723644_1	1348338.ADILRU_2233	7.347e-14	71.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4FS2S@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_73039_6	1123024.AUII01000003_gene3334	1.511e-106	354.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DXT5@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR21617310_k127_73039_5	882083.SacmaDRAFT_4397	2.126e-116	384.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DYJ1@85010|Pseudonocardiales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR21617310_k127_73039_4	351607.Acel_1119	7.492e-137	460.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4ERFP@85013|Frankiales	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_73039_2	882083.SacmaDRAFT_4399	1.771e-145	486.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR21617310_k127_73039_8	1120949.KB903327_gene5330	3.816e-84	301.0	COG4166@1|root,COG4166@2|Bacteria,2IIU5@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_73039_3	471852.Tcur_2881	2.219e-144	479.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EG83@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_73039_1	469371.Tbis_1445	2.43e-158	524.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_73039_0	1120950.KB892720_gene1878	4.889e-251	790.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPKW@85009|Propionibacteriales	201174|Actinobacteria	EU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR21617310_k127_73039_7	471852.Tcur_4376	7.721e-97	323.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4EIBF@85012|Streptosporangiales	201174|Actinobacteria	J	Metallopeptidase family M24	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR21617310_k127_73308_0	1380393.JHVP01000005_gene3550	2.146e-280	880.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR21617310_k127_73308_2	439235.Dalk_0098	1.408e-08	56.0	COG0500@1|root,COG2226@2|Bacteria,1R9JW@1224|Proteobacteria,42M76@68525|delta/epsilon subdivisions,2WK4P@28221|Deltaproteobacteria,2MPDX@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR21617310_k127_73308_1	351160.RCIX1494	3.192e-55	207.0	arCOG11014@1|root,arCOG11014@2157|Archaea	2157|Archaea	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR21617310_k127_742081_2	1380356.JNIK01000018_gene848	1.011e-31	132.0	2E9HK@1|root,333QQ@2|Bacteria,2I89Z@201174|Actinobacteria,4ETI2@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_742081_0	227882.SAV_748	1.456e-61	240.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR21617310_k127_742081_1	446470.Snas_3863	2.826e-57	217.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4EZK2@85014|Glycomycetales	201174|Actinobacteria	K	PFAM transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,TPR_7,Trans_reg_C
SRR21617310_k127_743478_1	73044.JNXP01000012_gene3796	8.994e-188	602.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR21617310_k127_743478_4	298655.KI912267_gene6751	1.677e-124	423.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4EX6N@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR21617310_k127_743478_5	1237500.ANBA01000018_gene3824	1.39e-122	406.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4EH4W@85012|Streptosporangiales	201174|Actinobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR21617310_k127_743478_0	525909.Afer_1529	1.033e-197	631.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CNJW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR21617310_k127_743478_2	471852.Tcur_3546	4.345e-177	571.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4ER2C@85012|Streptosporangiales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR21617310_k127_743478_3	35754.JNYJ01000049_gene7875	3.018e-151	484.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4DASF@85008|Micromonosporales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR21617310_k127_743478_6	1894.JOER01000024_gene6800	8.305e-67	233.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria	201174|Actinobacteria	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR21617310_k127_745094_0	58123.JOFJ01000005_gene1571	5.197e-202	647.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4EN5U@85012|Streptosporangiales	201174|Actinobacteria	FL	LAGLIDADG-like domain	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR21617310_k127_745094_4	1121422.AUMW01000005_gene639	3.665e-40	156.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR21617310_k127_745094_6	702459.BBPR_0543	1.548e-08	62.0	COG1388@1|root,COG1388@2|Bacteria,2HVH4@201174|Actinobacteria,4D1G8@85004|Bifidobacteriales	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR21617310_k127_745094_2	512565.AMIS_68930	1e-68	240.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4D8KV@85008|Micromonosporales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR21617310_k127_745094_1	1121866.AUGK01000004_gene150	2.025e-114	394.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CUJD@84998|Coriobacteriia	84998|Coriobacteriia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR21617310_k127_745094_3	105422.BBPM01000008_gene6365	6.456e-63	225.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,2NHWR@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_745094_5	102232.GLO73106DRAFT_00019790	1.723e-38	147.0	COG0436@1|root,COG0436@2|Bacteria,1G2TF@1117|Cyanobacteria	1117|Cyanobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_745524_0	1435356.Y013_04860	7.708e-101	335.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4FV7E@85025|Nocardiaceae	201174|Actinobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR21617310_k127_745524_3	345341.KUTG_10190	2.029e-20	92.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR21617310_k127_745524_4	1463857.JOFZ01000011_gene2218	2.999e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,2GM6X@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_745524_1	768671.ThimaDRAFT_0510	1.644e-35	141.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_748180_1	543632.JOJL01000119_gene275	2.983e-85	297.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR21617310_k127_748180_0	67267.JNXT01000128_gene5246	1.427e-98	341.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR21617310_k127_748180_2	1032480.MLP_18830	1.031e-18	94.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_748180_3	408672.NBCG_01293	0.0002645	47.0	COG0577@1|root,COG0577@2|Bacteria,2GJRC@201174|Actinobacteria,4DU1E@85009|Propionibacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR21617310_k127_751570_2	644966.Tmar_2343	5.234e-119	415.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,3WCDS@538999|Clostridiales incertae sedis	186801|Clostridia	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR21617310_k127_751570_4	266940.Krad_1307	4.759e-89	307.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR21617310_k127_751570_3	269800.Tfu_0597	7.127e-115	382.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4EI5Q@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR21617310_k127_751570_7	929712.KI912613_gene1337	2.422e-14	86.0	COG0620@1|root,COG0620@2|Bacteria,2HQU3@201174|Actinobacteria,4CSK8@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_751570_5	405948.SACE_1182	1.057e-76	265.0	COG1011@1|root,COG1011@2|Bacteria,2GN3E@201174|Actinobacteria,4E9V4@85010|Pseudonocardiales	201174|Actinobacteria	S	HAD superfamily	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR21617310_k127_751570_6	1068978.AMETH_0236	2.036e-17	97.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DXB6@85010|Pseudonocardiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR21617310_k127_751570_1	1122182.KB903819_gene103	4.726e-153	497.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4D9EC@85008|Micromonosporales	201174|Actinobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR21617310_k127_751570_0	298653.Franean1_1082	2.026e-217	696.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4ES5B@85013|Frankiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR21617310_k127_751570_8	208439.AJAP_22960	5.064e-05	49.0	2EIY5@1|root,33CPB@2|Bacteria,2I391@201174|Actinobacteria,4E3MI@85010|Pseudonocardiales	201174|Actinobacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_755291_0	390989.JOEG01000001_gene4823	3.635e-78	281.0	COG3570@1|root,COG3570@2|Bacteria,2GZSC@201174|Actinobacteria,4DC6T@85008|Micromonosporales	201174|Actinobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRR21617310_k127_755291_1	373994.Riv7116_6559	8.187e-38	158.0	COG1357@1|root,COG1357@2|Bacteria,1G8T3@1117|Cyanobacteria,1HKQH@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR21617310_k127_756466_2	1121939.L861_23050	1.478e-59	219.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,1RYXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR21617310_k127_756466_0	1463917.JODC01000044_gene2168	6.304e-78	267.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR21617310_k127_756466_3	1206737.BAGF01000152_gene6434	2.581e-47	175.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria,4G2IM@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR21617310_k127_756466_1	909613.UO65_2318	3.533e-72	245.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria,4E4IC@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR21617310_k127_756466_4	143224.JQMD01000002_gene4059	1.385e-44	167.0	COG2374@1|root,COG2374@2|Bacteria,4P0WJ@976|Bacteroidetes,1I7VS@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_759137_13	211165.AJLN01000045_gene218	4.396e-60	214.0	COG1461@1|root,COG1461@2|Bacteria,1G4HX@1117|Cyanobacteria,1JHXG@1189|Stigonemataceae	1117|Cyanobacteria	S	Dak2	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR21617310_k127_759137_2	1120936.KB907226_gene2801	8.076e-154	503.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4EH3P@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_759137_4	1223523.H340_23753	6.852e-129	421.0	COG4221@1|root,COG4221@2|Bacteria,2I2YS@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR21617310_k127_759137_17	463191.SSEG_01247	5.272e-29	121.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR21617310_k127_759137_6	290399.Arth_0225	4.056e-119	392.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,1W7SI@1268|Micrococcaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR21617310_k127_759137_15	1214101.BN159_2830	1.709e-44	176.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria	201174|Actinobacteria	S	Dihydroxyacetone kinase	dak3	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR21617310_k127_759137_14	1394178.AWOO02000016_gene6945	1.378e-49	185.0	COG2917@1|root,COG2917@2|Bacteria,2IGTQ@201174|Actinobacteria,4EIRE@85012|Streptosporangiales	201174|Actinobacteria	D	probably involved in intracellular septation	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159,IspA
SRR21617310_k127_759137_21	1289387.AUKW01000023_gene3030	0.0001279	52.0	2BTN3@1|root,32NUZ@2|Bacteria,2GTXR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_759137_11	1136417.AZWE01000018_gene968	1.211e-77	290.0	COG2267@1|root,COG2267@2|Bacteria,2H3BR@201174|Actinobacteria,4DHTZ@85008|Micromonosporales	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_759137_18	1179773.BN6_72540	2.672e-22	107.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4E0I5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR21617310_k127_759137_9	1394178.AWOO02000026_gene5105	2.702e-95	328.0	COG0477@1|root,COG0477@2|Bacteria,2I607@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3
SRR21617310_k127_759137_19	479434.Sthe_3108	3.461e-14	81.0	COG0344@1|root,COG0344@2|Bacteria,2GBUF@200795|Chloroflexi,27ZAT@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR21617310_k127_759137_10	67267.JNXT01000025_gene3128	4.371e-89	306.0	COG1562@1|root,COG1562@2|Bacteria,2GNS9@201174|Actinobacteria	201174|Actinobacteria	I	Squalene phytoene synthase	hopE	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR21617310_k127_759137_8	1449347.JQLN01000007_gene894	2.054e-98	330.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,2M0MM@2063|Kitasatospora	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR21617310_k127_759137_3	1463895.JODA01000037_gene1853	1.439e-145	476.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria	201174|Actinobacteria	H	squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR21617310_k127_759137_7	1123320.KB889697_gene9000	5.751e-118	404.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hopB	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR21617310_k127_759137_0	1068978.AMETH_4077	1.333e-290	903.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4E0ZE@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Prenyltransferase and squalene oxidase repeat	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR21617310_k127_759137_16	1134445.AJJM01000148_gene1552	5.336e-34	144.0	COG0775@1|root,COG0775@2|Bacteria,2GKZD@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylase superfamily	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR21617310_k127_759137_1	351607.Acel_1699	5.402e-190	595.0	COG0535@1|root,COG0535@2|Bacteria,2HTDD@201174|Actinobacteria,4ES4M@85013|Frankiales	201174|Actinobacteria	F	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
SRR21617310_k127_759137_12	390989.JOEG01000019_gene5930	8.736e-74	270.0	COG0300@1|root,COG0300@2|Bacteria,2I2RM@201174|Actinobacteria,4D9SX@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR21617310_k127_759137_5	1146883.BLASA_0209	3.048e-121	396.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4ES1H@85013|Frankiales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR21617310_k127_763469_15	1385518.N798_01320	2.854e-20	94.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4FEJ3@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR21617310_k127_763469_11	196162.Noca_2635	9.058e-64	230.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4DQZM@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_763469_3	285535.JOEY01000018_gene7426	1.528e-151	496.0	COG0833@1|root,COG0833@2|Bacteria,2I418@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR21617310_k127_763469_2	42256.RradSPS_0553	1.82e-211	675.0	COG1506@1|root,COG1506@2|Bacteria,2GNG5@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR21617310_k127_763469_14	1236902.ANAS01000009_gene2619	6.864e-28	128.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4EJSG@85012|Streptosporangiales	201174|Actinobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR21617310_k127_763469_5	1121468.AUBR01000018_gene2687	2.881e-106	359.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,42F4H@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART Elongator protein 3 MiaB NifB	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR21617310_k127_763469_13	1313172.YM304_21140	5.625e-34	136.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria,4CN5U@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR21617310_k127_763469_7	266117.Rxyl_2726	1.788e-99	337.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria,4CQ3J@84995|Rubrobacteria	84995|Rubrobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR21617310_k127_763469_4	1137271.AZUM01000001_gene1097	1.221e-125	417.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4E0GZ@85010|Pseudonocardiales	201174|Actinobacteria	C	formate dehydrogenase, beta subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4
SRR21617310_k127_763469_0	882086.SacxiDRAFT_0135	0.0	1262.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4DZEM@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR21617310_k127_763469_9	219305.MCAG_00165	1.21e-83	282.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria	201174|Actinobacteria	C	Molybdopterin oxidoreductase, Fe4S4	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR21617310_k127_763469_6	298655.KI912266_gene5318	4.496e-101	341.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4ERI5@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR21617310_k127_763469_8	1869.MB27_19410	3.3e-85	294.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4D8HR@85008|Micromonosporales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR21617310_k127_763469_12	338966.Ppro_2543	3.915e-51	189.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR21617310_k127_763469_10	1416759.AYMR01000004_gene3486	9.024e-82	288.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4FM0K@85023|Microbacteriaceae	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR21617310_k127_763469_1	928724.SacglDRAFT_01393	1.657e-267	837.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4DX6U@85010|Pseudonocardiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR21617310_k127_763469_16	888439.HMPREF9240_00823	4.21e-20	95.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D66N@85005|Actinomycetales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR21617310_k127_763934_15	710111.FraQA3DRAFT_3675	2.418e-25	111.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR,MerR_1
SRR21617310_k127_763934_6	648996.Theam_1249	7.862e-109	361.0	COG0499@1|root,COG0499@2|Bacteria,2G3TI@200783|Aquificae	200783|Aquificae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR21617310_k127_763934_11	452652.KSE_36030	1.62e-45	175.0	COG1988@1|root,COG1988@2|Bacteria,2GMNG@201174|Actinobacteria,2M256@2063|Kitasatospora	201174|Actinobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR21617310_k127_763934_12	1463841.JOIR01000065_gene5399	5.318e-44	170.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR21617310_k127_763934_10	1120936.KB907212_gene5026	1.254e-45	175.0	COG5485@1|root,COG5485@2|Bacteria,2IFN0@201174|Actinobacteria,4EKAW@85012|Streptosporangiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR21617310_k127_763934_16	42256.RradSPS_0526	2.48e-12	74.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR21617310_k127_763934_14	1211815.CBYP010000075_gene2951	7.348e-37	152.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR21617310_k127_763934_0	351607.Acel_1545	1.659e-234	751.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR21617310_k127_763934_8	1123320.KB889640_gene4488	1.519e-74	267.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,SKI
SRR21617310_k127_763934_3	365528.KB891241_gene6214	1.807e-125	416.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_763934_5	1211815.CBYP010000061_gene55	1.068e-115	385.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4EUBY@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_763934_1	2074.JNYD01000019_gene2476	1.644e-201	641.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4DZCG@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR21617310_k127_763934_17	1064537.AGSO01000009_gene2107	1.258e-11	67.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FD7I@85020|Dermabacteraceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_763934_7	106370.Francci3_4435	9.577e-98	337.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4ESG4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_763934_4	266117.Rxyl_0145	1.702e-119	389.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR21617310_k127_763934_9	1283299.AUKG01000001_gene1850	2.367e-67	253.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4CPPP@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_763934_13	298654.FraEuI1c_0140	5.71e-42	168.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4ETKU@85013|Frankiales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR21617310_k127_763934_2	572547.Amico_1243	3.969e-172	549.0	COG1554@1|root,COG1554@2|Bacteria,3TBY3@508458|Synergistetes	508458|Synergistetes	G	PFAM glycoside hydrolase family 65 central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
SRR21617310_k127_765413_2	1043205.AFYF01000011_gene1404	3.723e-52	192.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4FEFS@85021|Intrasporangiaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR21617310_k127_765413_5	1386089.N865_14320	4.418e-18	86.0	COG2755@1|root,COG2755@2|Bacteria,2GMDE@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
SRR21617310_k127_765413_1	443218.AS9A_1103	6.795e-109	361.0	COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,236BW@1762|Mycobacteriaceae	201174|Actinobacteria	M	Choloylglycine hydrolase	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
SRR21617310_k127_765413_4	909613.UO65_1065	2.535e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4DZU6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_765413_0	469383.Cwoe_4755	1.709e-153	496.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR21617310_k127_765413_3	1157637.KB892103_gene1645	3.104e-42	159.0	COG2267@1|root,COG2267@2|Bacteria,2IBIY@201174|Actinobacteria	201174|Actinobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR21617310_k127_767236_0	192952.MM_2650	3.062e-103	347.0	COG0596@1|root,arCOG01648@2157|Archaea,2Y06J@28890|Euryarchaeota,2N9YM@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR21617310_k127_767236_1	1121877.JQKF01000010_gene743	1.422e-63	224.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_771886_10	1232410.KI421428_gene1058	6.426e-06	54.0	COG1341@1|root,COG1341@2|Bacteria,1NBYH@1224|Proteobacteria,42THE@68525|delta/epsilon subdivisions,2WR2N@28221|Deltaproteobacteria,43VXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	mRNA cleavage and polyadenylation factor CLP1 P-loop	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
SRR21617310_k127_771886_3	1120934.KB894449_gene3015	1.689e-77	270.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4E3VM@85010|Pseudonocardiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR21617310_k127_771886_0	1380356.JNIK01000018_gene742	9.916e-113	392.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4ESBP@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR21617310_k127_771886_8	465541.ATCJ01000005_gene4668	3.834e-16	91.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_771886_5	222534.KB893739_gene1434	1.145e-45	175.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4ERMT@85013|Frankiales	201174|Actinobacteria	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR21617310_k127_771886_7	926569.ANT_02430	5.698e-21	102.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_771886_9	926690.KE386573_gene2403	4.085e-16	81.0	arCOG08975@1|root,arCOG08975@2157|Archaea,2Y04U@28890|Euryarchaeota,23Y2M@183963|Halobacteria	183963|Halobacteria	S	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR21617310_k127_771886_2	1120950.KB892801_gene1776	3.362e-89	299.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4DPX5@85009|Propionibacteriales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR21617310_k127_771886_1	258533.BN977_04324	3.685e-91	316.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,233ZZ@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR21617310_k127_771886_4	1120985.AUMI01000005_gene2503	1.639e-68	246.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR21617310_k127_771886_6	326424.FRAAL0985	1.378e-40	159.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4ERW5@85013|Frankiales	201174|Actinobacteria	H	Uroporphyrinogen III synthase HEM4	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR21617310_k127_781110_0	1123320.KB889585_gene1866	1.435e-55	208.0	COG1309@1|root,COG1309@2|Bacteria,2IMC6@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR21617310_k127_781110_3	1120950.KB892744_gene2833	3.273e-26	113.0	2E7SB@1|root,3327J@2|Bacteria,2GRIZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
SRR21617310_k127_781110_1	1229172.JQFA01000002_gene3797	1.905e-53	193.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR21617310_k127_781110_4	1122182.KB903834_gene5770	3.712e-07	55.0	arCOG12798@1|root,2Z9Z0@2|Bacteria,2IK1X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_781110_2	591158.SSMG_07698	1.506e-30	138.0	2DUH0@1|root,33QKQ@2|Bacteria,2H29R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_787399_4	266117.Rxyl_0122	2.653e-66	236.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4CQQZ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_787399_8	47763.JNZA01000002_gene3222	1.607e-29	129.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_787399_9	1229780.BN381_450009	2.16e-23	115.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR21617310_k127_787399_2	234267.Acid_3505	1.424e-103	352.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR21617310_k127_787399_1	404589.Anae109_0240	1.36e-153	507.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
SRR21617310_k127_787399_10	929712.KI912613_gene1694	5.187e-21	100.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR21617310_k127_787399_3	1206739.BAGJ01000088_gene276	2.162e-71	252.0	COG4275@1|root,COG4275@2|Bacteria,2IK0B@201174|Actinobacteria,4G3EW@85025|Nocardiaceae	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR21617310_k127_787399_5	512565.AMIS_46940	1.458e-59	211.0	COG4275@1|root,COG4275@2|Bacteria,2IPJU@201174|Actinobacteria,4DJAJ@85008|Micromonosporales	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_787399_6	1499967.BAYZ01000024_gene278	3.683e-56	209.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR21617310_k127_787399_0	1120950.KB892770_gene1357	1.535e-194	615.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN0C@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_787399_7	1123320.KB889651_gene5085	1.278e-40	155.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR21617310_k127_787399_13	1122611.KB903954_gene5652	0.0009151	50.0	COG3391@1|root,COG3391@2|Bacteria,2GNC3@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_787399_12	1172180.KB911776_gene604	1.793e-10	72.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LGFP,PQQ_2,PQQ_3
SRR21617310_k127_789484_4	1157634.KB912971_gene1788	0.0002086	53.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_789484_0	749414.SBI_01735	5.541e-163	521.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR21617310_k127_789484_1	1223523.H340_08906	1.794e-112	382.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR21617310_k127_789484_3	1382356.JQMP01000001_gene1246	4.326e-07	63.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
SRR21617310_k127_789484_2	497964.CfE428DRAFT_3040	5.927e-12	74.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR21617310_k127_79292_2	1382356.JQMP01000003_gene1584	5.161e-27	116.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR21617310_k127_79292_1	1386089.N865_15125	1.319e-125	416.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4FH53@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_79292_0	1120950.KB892708_gene4380	5.078e-242	788.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DPKG@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR21617310_k127_799431_13	351160.RRC310	8.412e-16	79.0	COG3729@1|root,arCOG10926@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
SRR21617310_k127_799431_2	68194.JNXR01000008_gene1822	3.084e-166	537.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR21617310_k127_799431_1	649831.L083_2860	1.736e-179	579.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4D8SF@85008|Micromonosporales	2|Bacteria	G	alpha amylase, catalytic	-	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR21617310_k127_799431_0	365528.KB891230_gene2022	1.559e-189	596.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4ERYP@85013|Frankiales	201174|Actinobacteria	I	PFAM Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR21617310_k127_799431_8	436229.JOEH01000010_gene5321	6.841e-39	153.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,2NG3F@228398|Streptacidiphilus	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR21617310_k127_799431_11	298655.KI912266_gene1145	1.122e-30	125.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria,4ET55@85013|Frankiales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR21617310_k127_799431_4	42256.RradSPS_0504	2.346e-109	381.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR21617310_k127_799431_9	266117.Rxyl_1043	5.683e-32	141.0	COG5650@1|root,COG5650@2|Bacteria,2HYCN@201174|Actinobacteria,4CQKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR21617310_k127_799431_12	471852.Tcur_4949	1.562e-24	111.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4EJVI@85012|Streptosporangiales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR21617310_k127_799431_6	164757.Mjls_5745	4.328e-48	176.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,232AP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR21617310_k127_799431_10	67352.JODS01000003_gene1947	6.875e-31	123.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR21617310_k127_799431_7	351607.Acel_2130	1.462e-46	171.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4ESST@85013|Frankiales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR21617310_k127_799431_3	457429.ABJI02000396_gene6742	2.096e-163	537.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR21617310_k127_799431_5	1068980.ARVW01000001_gene878	8.541e-92	323.0	COG3173@1|root,COG3173@2|Bacteria,2HH8W@201174|Actinobacteria,4E34T@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
SRR21617310_k127_801948_2	247490.KSU1_C1707	1.053e-138	449.0	COG0451@1|root,COG0451@2|Bacteria,2J0GN@203682|Planctomycetes	203682|Planctomycetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR21617310_k127_801948_0	1146883.BLASA_0347	2.049e-153	508.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4ERU6@85013|Frankiales	201174|Actinobacteria	GM	Polysaccharide biosynthesis protein	capD	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR21617310_k127_801948_1	1146883.BLASA_0346	3.346e-151	512.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4ERD8@85013|Frankiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpA	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR21617310_k127_801948_4	2074.JNYD01000011_gene26	7.746e-119	394.0	2ART5@1|root,31H4G@2|Bacteria,2I83W@201174|Actinobacteria,4E9S3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_801948_5	700598.Niako_5329	6.451e-115	399.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,F5_F8_type_C,IgGFc_binding,PA14,PKD,Peptidase_M43,Transglut_core
SRR21617310_k127_801948_7	1042377.AFPJ01000034_gene2380	8.583e-05	56.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,46AA7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Chitinase C	-	-	3.2.1.14,3.2.1.202	ko:K01183,ko:K21606	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	CBM5,GH18	-	CBM_5_12_2,ChiC,Glyco_hydro_18
SRR21617310_k127_801948_3	1463887.KL589986_gene3036	1.826e-133	434.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR21617310_k127_801948_6	751945.Theos_1547	7.173e-22	108.0	COG1216@1|root,COG1216@2|Bacteria,1WJXS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Glycosyl transferase family 2	-	-	2.4.1.287	ko:K16649	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR21617310_k127_807897_5	443255.SCLAV_0442	1.825e-30	130.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR21617310_k127_807897_0	1289387.AUKW01000003_gene2702	1.755e-75	265.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_807897_2	1463825.JNXC01000021_gene7301	7.032e-46	182.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DYPN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyI	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR21617310_k127_807897_4	383372.Rcas_1535	1.921e-36	154.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi,376TJ@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_807897_6	1463856.JOHY01000039_gene1649	1.101e-11	76.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_807897_7	666685.R2APBS1_3944	0.0003126	51.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1X7MS@135614|Xanthomonadales	135614|Xanthomonadales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR21617310_k127_807897_1	134676.ACPL_1738	2.27e-46	180.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4DA6N@85008|Micromonosporales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_807897_3	211114.JOEF01000043_gene6079	1.81e-39	150.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4DZGC@85010|Pseudonocardiales	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR21617310_k127_817893_4	526225.Gobs_4336	1.3e-09	67.0	COG0318@1|root,COG0318@2|Bacteria,2GIX4@201174|Actinobacteria,4EXHB@85013|Frankiales	201174|Actinobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR21617310_k127_817893_1	234267.Acid_7158	1.616e-73	268.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,3Y6IT@57723|Acidobacteria	57723|Acidobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12
SRR21617310_k127_817893_0	864702.OsccyDRAFT_1593	1.802e-81	279.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_817893_3	1463879.JOHP01000004_gene6498	8.697e-42	164.0	COG1607@1|root,COG1607@2|Bacteria,2GK6X@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA hydrolase	-	-	3.1.2.23	ko:K01075,ko:K10806	ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR21617310_k127_817893_2	479432.Sros_6982	2.319e-64	251.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJS4@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR21617310_k127_825454_3	15368.BRADI1G30470.1	4.886e-06	48.0	COG0328@1|root,2QRR5@2759|Eukaryota,37QNM@33090|Viridiplantae,3G9CP@35493|Streptophyta,3KZ1R@4447|Liliopsida,3I634@38820|Poales	35493|Streptophyta	L	Caulimovirus viroplasmin	-	-	-	-	-	-	-	-	-	-	-	-	Cauli_VI,RVT_3
SRR21617310_k127_825454_1	258533.BN977_01312	5.084e-17	85.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,234GG@1762|Mycobacteriaceae	201174|Actinobacteria	GL	Ribonuclease	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR21617310_k127_825454_4	1064537.AGSO01000023_gene3095	0.000138	54.0	COG0507@1|root,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	traA	-	-	-	-	-	-	-	-	-	-	-	AAA_30,PDDEXK_1,TrwC,UvrD-helicase,UvrD_C
SRR21617310_k127_825454_0	1137271.AZUM01000010_gene1714	1.738e-35	149.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR21617310_k127_825454_2	1172188.KB911821_gene1956	1.101e-10	64.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4FI4Q@85021|Intrasporangiaceae	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_825561_2	28444.JODQ01000016_gene7091	4.229e-24	103.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4EHBT@85012|Streptosporangiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR21617310_k127_825561_0	1157637.KB892111_gene4201	1.67e-86	299.0	COG2267@1|root,COG2267@2|Bacteria,2GU81@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_825561_1	671143.DAMO_2337	2.825e-37	148.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR21617310_k127_825561_4	562970.Btus_3320	8.819e-09	65.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,2789V@186823|Alicyclobacillaceae	91061|Bacilli	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR21617310_k127_825561_5	1120950.KB892762_gene5470	3.344e-07	55.0	COG0477@1|root,COG2814@2|Bacteria,2HU7R@201174|Actinobacteria,4DWA7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR21617310_k127_825561_3	1009370.ALO_01315	9.097e-16	85.0	COG2890@1|root,COG2890@2|Bacteria,1UMJ4@1239|Firmicutes,4H38D@909932|Negativicutes	909932|Negativicutes	K	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	TehB
SRR21617310_k127_826206_1	395494.Galf_2723	1.348e-10	68.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_826206_2	264732.Moth_1992	7.191e-09	64.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_826206_0	68219.JNXI01000010_gene5730	6.252e-84	287.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_828276_2	525904.Tter_1654	1.26e-112	390.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR21617310_k127_828276_3	927704.SELR_03390	8.813e-80	280.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR21617310_k127_828276_5	525909.Afer_1810	1.413e-30	121.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR21617310_k127_828276_1	1957.JODX01000005_gene3519	2.917e-158	525.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR21617310_k127_828276_0	986075.CathTA2_0500	1.404e-189	616.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli	91061|Bacilli	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR21617310_k127_828276_4	500153.JOEK01000002_gene313	1.211e-60	221.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR21617310_k127_828276_6	561175.KB894093_gene2955	5.222e-13	69.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4EGAS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_838718_24	35754.JNYJ01000043_gene4511	0.0002377	46.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4DAVA@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR21617310_k127_838718_9	1122611.KB903996_gene7554	4.878e-61	227.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4EFFN@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR21617310_k127_838718_14	1449346.JQMO01000003_gene4784	1.305e-34	143.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,2M0I6@2063|Kitasatospora	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_838718_11	1122611.KB903996_gene7555	1.767e-56	215.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EP82@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR21617310_k127_838718_20	1298880.AUEV01000006_gene4133	9.838e-15	84.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_838718_4	1382306.JNIM01000001_gene1934	1.214e-90	308.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR21617310_k127_838718_2	1123321.KB905814_gene1791	4.62e-114	375.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR21617310_k127_838718_21	266117.Rxyl_2561	8.772e-13	82.0	COG3119@1|root,COG3119@2|Bacteria,2HRVJ@201174|Actinobacteria,4CTZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_838718_7	526225.Gobs_2081	9.393e-64	243.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR21617310_k127_838718_16	367299.JOEE01000011_gene3181	7.682e-29	124.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4FGVH@85021|Intrasporangiaceae	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951,ko:K07065	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR21617310_k127_838718_19	656024.FsymDg_3842	9.649e-15	84.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR21617310_k127_838718_3	656024.FsymDg_3843	1.598e-96	323.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4ES4I@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR21617310_k127_838718_1	365528.KB891208_gene3139	1.155e-126	413.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4ES4I@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR21617310_k127_838718_5	656024.FsymDg_3844	2.605e-88	311.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4ERNM@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR21617310_k127_838718_0	351607.Acel_0651	2.085e-233	735.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4ERF0@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR21617310_k127_838718_13	1449355.JQNR01000005_gene4434	4.964e-46	176.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR21617310_k127_838718_15	649831.L083_7065	2.036e-30	136.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4DCTW@85008|Micromonosporales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR21617310_k127_838718_17	471856.Jden_1779	9.151e-23	99.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR21617310_k127_838718_12	298654.FraEuI1c_0934	1.822e-56	206.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4ETD3@85013|Frankiales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR21617310_k127_838718_22	471852.Tcur_3923	1.501e-11	73.0	COG5336@1|root,COG5336@2|Bacteria,2GWR5@201174|Actinobacteria,4EQK4@85012|Streptosporangiales	201174|Actinobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR21617310_k127_838718_23	590998.Celf_2806	6.707e-07	57.0	2BJAR@1|root,32DKN@2|Bacteria,2GR4T@201174|Actinobacteria,4F1BV@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_838718_6	1380347.JNII01000007_gene587	1.334e-86	307.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4ERX0@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR21617310_k127_838718_18	1449126.JQKL01000005_gene859	6.553e-18	93.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR21617310_k127_838718_10	211114.JOEF01000005_gene2170	9.645e-58	211.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DY0G@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR21617310_k127_838718_8	1304865.JAGF01000001_gene136	2.979e-62	223.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria,4F21R@85016|Cellulomonadaceae	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR21617310_k127_850834_4	479432.Sros_4184	1.722e-10	64.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ENIC@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_850834_0	1120936.KB907211_gene263	2.13e-64	229.0	COG1309@1|root,COG1309@2|Bacteria,2GNBS@201174|Actinobacteria,4EK2F@85012|Streptosporangiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR21617310_k127_850834_2	1380393.JHVP01000001_gene2240	4.985e-61	223.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4ESAR@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD, ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR21617310_k127_850834_1	1120949.KB903328_gene8838	1.689e-61	216.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_850834_3	1121946.AUAX01000010_gene3769	1.146e-38	149.0	2AY0M@1|root,31Q26@2|Bacteria,2IMBI@201174|Actinobacteria,4DGA5@85008|Micromonosporales	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR21617310_k127_851319_0	543526.Htur_2519	2.226e-34	150.0	COG0642@1|root,arCOG02327@2157|Archaea,2XTH8@28890|Euryarchaeota,23S6Q@183963|Halobacteria	183963|Halobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_8
SRR21617310_k127_851319_3	1278073.MYSTI_07395	2.805e-10	62.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C1T@68525|delta/epsilon subdivisions,2X7CE@28221|Deltaproteobacteria,2Z3MI@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR21617310_k127_851319_2	298655.KI912266_gene4920	9.449e-15	80.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4ES8N@85013|Frankiales	201174|Actinobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR21617310_k127_851319_1	1463857.JOFZ01000015_gene958	1.427e-15	87.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR21617310_k127_853413_0	469371.Tbis_1999	0.0	1366.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DXXG@85010|Pseudonocardiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR21617310_k127_853413_10	287986.DV20_14370	4.069e-52	196.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4DY0X@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_853413_5	1120936.KB907209_gene1337	4.842e-134	447.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4EGHZ@85012|Streptosporangiales	201174|Actinobacteria	M	NTF2-like N-terminal transpeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR21617310_k127_853413_1	106370.Francci3_1626	2.669e-303	944.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR21617310_k127_853413_4	326427.Cagg_2558	3.49e-155	502.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,374XF@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR21617310_k127_853413_14	235985.BBPN01000022_gene2574	6.419e-17	94.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DLH
SRR21617310_k127_853413_12	235985.BBPN01000022_gene2573	1.015e-30	138.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DLH
SRR21617310_k127_853413_7	485913.Krac_5382	3.133e-68	243.0	2DM3D@1|root,31J5I@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
SRR21617310_k127_853413_13	1449063.JMLS01000001_gene4113	1.218e-27	121.0	COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,26QYS@186822|Paenibacillaceae	91061|Bacilli	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR21617310_k127_853413_9	1348663.KCH_20490	3.611e-52	191.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,2M2KZ@2063|Kitasatospora	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR21617310_k127_853413_3	471852.Tcur_2850	1.36e-192	615.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4EGQY@85012|Streptosporangiales	201174|Actinobacteria	J	Ribosomal protein S1-like RNA-binding domain	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR21617310_k127_853413_8	485913.Krac_8827	5.106e-68	239.0	COG2872@1|root,COG2872@2|Bacteria,2GA6P@200795|Chloroflexi	200795|Chloroflexi	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR21617310_k127_853413_2	1150864.MILUP08_45007	7.358e-274	871.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4D8IE@85008|Micromonosporales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR21617310_k127_853413_16	1120936.KB907210_gene5643	2.66e-14	73.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_853413_11	749927.AMED_6143	6.277e-47	177.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4DYKY@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_853413_17	58123.JOFJ01000001_gene2975	7.741e-08	57.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4EMF7@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_853413_15	2002.JOEQ01000024_gene169	1.405e-14	77.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4EMF7@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_853413_6	1386089.N865_00710	1.974e-120	398.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FG5U@85021|Intrasporangiaceae	201174|Actinobacteria	E	branched-chain amino acid	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_855892_6	1283283.ATXA01000014_gene3593	3.341e-132	438.0	COG1018@1|root,COG1018@2|Bacteria,2HE37@201174|Actinobacteria,4ERN2@85013|Frankiales	201174|Actinobacteria	C	Ferric reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
SRR21617310_k127_855892_39	1172188.KB911831_gene4029	1.716e-13	77.0	COG3976@1|root,COG3976@2|Bacteria,2IP4J@201174|Actinobacteria,4FH0T@85021|Intrasporangiaceae	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
SRR21617310_k127_855892_16	591159.ACEZ01000137_gene2229	6.667e-69	247.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_2
SRR21617310_k127_855892_38	1133850.SHJG_0930	1.547e-14	83.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_2
SRR21617310_k127_855892_11	1155718.KB891883_gene5944	1.551e-87	296.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcsR4	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_855892_17	68219.JNXI01000010_gene5736	9.882e-68	246.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR21617310_k127_855892_37	1089544.KB912942_gene1813	7.478e-21	102.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GKGS@201174|Actinobacteria	2|Bacteria	C	Oxidoreductase FAD-binding domain	paaE	GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.18.1.3	ko:K00529,ko:K02613	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783,R09838	RC00098,RC02690	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A1479	FAD_binding_6,Fer2,NAD_binding_1
SRR21617310_k127_855892_41	446462.Amir_1181	2.955e-11	71.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,4E52U@85010|Pseudonocardiales	201174|Actinobacteria	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
SRR21617310_k127_855892_30	1463853.JOHW01000002_gene5702	1.723e-34	141.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_855892_25	1894.JOER01000044_gene6729	5.243e-48	184.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_855892_2	710696.Intca_3585	8.589e-179	577.0	COG3055@1|root,COG3055@2|Bacteria,2I9Q1@201174|Actinobacteria	201174|Actinobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_855892_32	479435.Kfla_5483	1.041e-30	139.0	COG5516@1|root,COG5516@2|Bacteria,2GJZN@201174|Actinobacteria,4DWU3@85009|Propionibacteriales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR21617310_k127_855892_14	479435.Kfla_5484	7.264e-80	288.0	COG0477@1|root,COG2814@2|Bacteria,2HDWW@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_855892_33	318424.EU78_00615	2.247e-29	127.0	COG0500@1|root,COG2226@2|Bacteria,2GJAI@201174|Actinobacteria,235CG@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_855892_13	1305732.JAGG01000001_gene1180	3.313e-80	277.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4FKUK@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR21617310_k127_855892_1	67352.JODS01000007_gene4566	3.953e-189	604.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR21617310_k127_855892_18	1382304.JNIL01000001_gene2044	1.038e-65	235.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,27859@186823|Alicyclobacillaceae	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR21617310_k127_855892_19	1120944.JONS01000033_gene3080	2.378e-65	244.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4D3QK@85005|Actinomycetales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR21617310_k127_855892_22	1120950.KB892810_gene7211	4.418e-61	222.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4DPS0@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR21617310_k127_855892_7	1089553.Tph_c28340	9.248e-132	435.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,42ERJ@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRR21617310_k127_855892_8	351607.Acel_1946	8.756e-118	395.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4ERS5@85013|Frankiales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR21617310_k127_855892_5	1394178.AWOO02000058_gene661	6.82e-156	503.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4EGAZ@85012|Streptosporangiales	201174|Actinobacteria	L	ATP dependent DNA ligase domain	ligC	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR21617310_k127_855892_24	1463917.JODC01000005_gene6994	4.495e-51	187.0	2E5FQ@1|root,3307E@2|Bacteria,2INDB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_855892_26	479431.Namu_4549	2.137e-45	175.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4ESJF@85013|Frankiales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR21617310_k127_855892_23	326424.FRAAL6266	1.937e-55	201.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4ESK5@85013|Frankiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR21617310_k127_855892_15	1160718.SU9_21332	1.175e-74	263.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_855892_10	446462.Amir_0158	1.238e-96	332.0	COG2232@1|root,COG2232@2|Bacteria,2IDDC@201174|Actinobacteria,4DXWM@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_855892_0	1137269.AZWL01000034_gene2457	0.0	1143.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR21617310_k127_855892_36	1121091.AUMP01000004_gene2351	1.289e-22	110.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli	91061|Bacilli	M	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
SRR21617310_k127_855892_21	292459.STH3231	4.212e-61	227.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia	186801|Clostridia	K	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR21617310_k127_855892_3	319795.Dgeo_0004	2.353e-177	565.0	COG0148@1|root,COG0148@2|Bacteria,1WIST@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR21617310_k127_855892_40	66429.JOFL01000004_gene3591	2.43e-13	78.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria	201174|Actinobacteria	D	septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR21617310_k127_855892_35	1033734.CAET01000082_gene3420	1.325e-26	115.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus	91061|Bacilli	J	RNA binding protein (contains ribosomal protein S1 domain)	yabR	-	-	ko:K07571	-	-	-	-	ko00000	-	-	-	S1
SRR21617310_k127_855892_28	351607.Acel_1907	6.175e-42	162.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4ESU2@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR21617310_k127_855892_12	68199.JNZO01000005_gene251	8.849e-83	294.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR21617310_k127_855892_29	1274.HX89_11075	2.095e-40	156.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,1ZVWG@145357|Dermacoccaceae	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR21617310_k127_855892_31	318424.EU78_22410	2.315e-32	143.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,23733@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_855892_27	485913.Krac_7714	1.915e-44	171.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR21617310_k127_855892_9	675635.Psed_0943	1.37e-103	349.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DYKF@85010|Pseudonocardiales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR21617310_k127_855892_4	479434.Sthe_2024	3.703e-174	558.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR21617310_k127_855892_20	35754.JNYJ01000004_gene5820	4.903e-64	226.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DAII@85008|Micromonosporales	201174|Actinobacteria	E	Cys met metabolism pyridoxal-phosphate-dependent	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR21617310_k127_85813_0	1463864.JOGO01000111_gene4329	1.586e-265	850.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR21617310_k127_85813_1	1122611.KB903983_gene3528	8.547e-152	483.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4EHJY@85012|Streptosporangiales	201174|Actinobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR21617310_k127_85813_3	471852.Tcur_4141	3.251e-102	344.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria,4EHR0@85012|Streptosporangiales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR21617310_k127_85813_4	471852.Tcur_4140	2.006e-100	342.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria,4EH66@85012|Streptosporangiales	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR21617310_k127_85813_7	1120936.KB907227_gene2992	7.267e-09	59.0	2B1FJ@1|root,31TWB@2|Bacteria,2GT4D@201174|Actinobacteria,4EKFY@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_85813_6	561175.KB894093_gene3178	3.095e-10	72.0	COG4961@1|root,COG4961@2|Bacteria,2I36X@201174|Actinobacteria,4ER8X@85012|Streptosporangiales	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR21617310_k127_85813_5	1394178.AWOO02000114_gene502	8.722e-20	100.0	2AQHK@1|root,31FQ6@2|Bacteria,2I1FE@201174|Actinobacteria,4EK4S@85012|Streptosporangiales	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR21617310_k127_85813_2	561175.KB894093_gene3175	3.71e-130	436.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,4EHDB@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR21617310_k127_867085_6	1380386.JIAW01000030_gene3601	2.323e-72	252.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,237K0@1762|Mycobacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR21617310_k127_867085_3	1382356.JQMP01000003_gene1735	9.767e-84	285.0	COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi	200795|Chloroflexi	G	Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR21617310_k127_867085_7	1323361.JPOC01000013_gene3775	9.347e-58	213.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4G9I9@85025|Nocardiaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_867085_9	1122609.AUGT01000023_gene572	1.058e-24	118.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR21617310_k127_867085_5	1463857.JOFZ01000011_gene2163	3.973e-79	273.0	COG2084@1|root,COG2084@2|Bacteria,2IRVU@201174|Actinobacteria	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
SRR21617310_k127_867085_4	1120949.KB903294_gene4204	2.336e-81	273.0	COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria	201174|Actinobacteria	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_867085_1	1380386.JIAW01000030_gene3584	7.619e-134	436.0	COG1840@1|root,COG1840@2|Bacteria,2GUG5@201174|Actinobacteria,23EGG@1762|Mycobacteriaceae	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR21617310_k127_867085_2	1380386.JIAW01000030_gene3589	2.44e-124	409.0	COG1840@1|root,COG1840@2|Bacteria,2GUG5@201174|Actinobacteria,23EGG@1762|Mycobacteriaceae	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR21617310_k127_867085_0	1380386.JIAW01000030_gene3590	2.889e-251	790.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2392Z@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1,SBP_bac_6
SRR21617310_k127_867085_8	1380386.JIAW01000030_gene3591	2.747e-48	177.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,23CXF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR21617310_k127_867669_6	65497.JODV01000012_gene2383	4.749e-103	355.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EEE4@85010|Pseudonocardiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR21617310_k127_867669_4	1449353.JQMQ01000004_gene5918	1.114e-121	398.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,2NHS8@228398|Streptacidiphilus	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR21617310_k127_867669_2	28042.GU90_17140	1.947e-162	528.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4E1VU@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR21617310_k127_867669_0	1122611.KB903948_gene6662	1.403e-243	765.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4EFGA@85012|Streptosporangiales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR21617310_k127_867669_8	298654.FraEuI1c_1589	4.915e-54	196.0	COG0500@1|root,COG0500@2|Bacteria,2I3S9@201174|Actinobacteria	201174|Actinobacteria	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR21617310_k127_867669_7	42256.RradSPS_0764	3.628e-87	308.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR21617310_k127_867669_9	1122933.JNIY01000012_gene1316	3.965e-51	196.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria	201174|Actinobacteria	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR21617310_k127_867669_12	1463903.JOIZ01000008_gene4357	1.293e-29	131.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_867669_16	377629.TERTU_0513	2.077e-05	55.0	COG3693@1|root,COG3693@2|Bacteria,1Q4ED@1224|Proteobacteria,1SYNN@1236|Gammaproteobacteria,2PPXI@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 10	cex	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
SRR21617310_k127_867669_5	68170.KL590506_gene9752	1.058e-109	394.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2GKKQ@201174|Actinobacteria,4DYP0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	embR	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
SRR21617310_k127_867669_15	102129.Lepto7375DRAFT_2232	1.971e-10	70.0	COG1309@1|root,COG1309@2|Bacteria,1G51N@1117|Cyanobacteria,1HB9N@1150|Oscillatoriales	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR21617310_k127_867669_11	329726.AM1_1229	1.249e-31	131.0	COG1309@1|root,COG1309@2|Bacteria,1G51N@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR21617310_k127_867669_1	68170.KL590506_gene9752	7.546e-181	619.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2GKKQ@201174|Actinobacteria,4DYP0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	embR	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
SRR21617310_k127_867669_17	644283.Micau_1879	0.0004509	46.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria,4D9F9@85008|Micromonosporales	201174|Actinobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR21617310_k127_867669_13	288705.RSal33209_0573	3.062e-27	123.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,1WAWG@1268|Micrococcaceae	201174|Actinobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Viral_helicase1
SRR21617310_k127_867669_3	1120950.KB892800_gene1626	1.13e-124	411.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DP18@85009|Propionibacteriales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
SRR21617310_k127_867669_10	67315.JOBD01000019_gene7554	7.583e-33	146.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR21617310_k127_867669_14	1382356.JQMP01000003_gene1492	2.926e-26	119.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_868443_7	929712.KI912613_gene3657	5.566e-08	63.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4CQ50@84995|Rubrobacteria	84995|Rubrobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_868443_5	227882.SAV_7507	3.943e-10	68.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR21617310_k127_868443_2	1123277.KB893173_gene1795	8.887e-35	140.0	COG1661@1|root,COG1661@2|Bacteria,4NPS1@976|Bacteroidetes,47PS2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR21617310_k127_868443_3	1173027.Mic7113_0724	5.802e-31	132.0	COG4976@1|root,COG4976@2|Bacteria,1G290@1117|Cyanobacteria,1H9JI@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR21617310_k127_868443_6	263358.VAB18032_28996	9.116e-10	68.0	COG0305@1|root,COG0305@2|Bacteria,2I62I@201174|Actinobacteria,4DANC@85008|Micromonosporales	201174|Actinobacteria	L	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987,DnaB
SRR21617310_k127_868443_0	345341.KUTG_06859	4.345e-105	345.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4E3VZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR21617310_k127_868443_1	1429046.RR21198_1866	8.465e-102	342.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2GN4Z@201174|Actinobacteria,4FW5A@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
SRR21617310_k127_868443_4	1116232.AHBF01000121_gene4226	7.876e-16	89.0	2DBRD@1|root,2ZAJS@2|Bacteria,2GM8P@201174|Actinobacteria	201174|Actinobacteria	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR21617310_k127_872616_0	479432.Sros_6897	3.102e-109	367.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_872616_1	1121946.AUAX01000003_gene1632	2.771e-24	109.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR21617310_k127_872616_2	196162.Noca_0128	1.995e-22	112.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2IF18@201174|Actinobacteria,4DN6C@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR21617310_k127_872616_3	345341.KUTG_09373	8.267e-14	75.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4E3G1@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigC	GO:0001101,GO:0001666,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0036293,GO:0042221,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065007,GO:0070482,GO:0080090,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR21617310_k127_878041_0	1957.JODX01000014_gene1029	1.724e-161	518.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR21617310_k127_878041_10	1206720.BAFQ01000083_gene2156	3.257e-40	161.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4FXAB@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR21617310_k127_878041_1	351607.Acel_1233	5.431e-139	456.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4ERXN@85013|Frankiales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR21617310_k127_878041_11	1137269.AZWL01000002_gene6164	1.034e-39	157.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR21617310_k127_878041_6	1120950.KB892761_gene5827	9.694e-53	195.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4DQED@85009|Propionibacteriales	201174|Actinobacteria	F	Cytidylate kinase	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR21617310_k127_878041_7	1121423.JONT01000014_gene1231	1.318e-51	199.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,260K3@186807|Peptococcaceae	186801|Clostridia	E	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR21617310_k127_878041_4	269800.Tfu_1206	6.018e-64	243.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4EFVZ@85012|Streptosporangiales	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR21617310_k127_878041_8	351607.Acel_1237	1.277e-50	198.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4ESM8@85013|Frankiales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR21617310_k127_878041_5	66429.JOFL01000033_gene3971	1.728e-61	220.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR21617310_k127_878041_9	264732.Moth_1362	1.468e-43	167.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,42FD9@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR21617310_k127_878041_2	997346.HMPREF9374_0364	7.759e-120	401.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,27B8E@186824|Thermoactinomycetaceae	91061|Bacilli	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR21617310_k127_878041_12	1122609.AUGT01000002_gene4077	2.746e-27	115.0	2E3JK@1|root,32YHZ@2|Bacteria,2GS0Y@201174|Actinobacteria,4DRQ0@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_878041_3	351607.Acel_1240	5.735e-93	309.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR21617310_k127_878739_1	1449976.KALB_3571	5.526e-33	138.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4E3MM@85010|Pseudonocardiales	201174|Actinobacteria	T	CBS-domain-containing membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR21617310_k127_878739_0	595460.RRSWK_03757	0.0	1457.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2IYDT@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR21617310_k127_881397_0	644283.Micau_3721	7.834e-136	446.0	COG1020@1|root,COG1020@2|Bacteria,2GSRJ@201174|Actinobacteria,4DGWB@85008|Micromonosporales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
SRR21617310_k127_881397_4	644283.Micau_3710	3.619e-90	306.0	COG1304@1|root,COG1304@2|Bacteria,2I442@201174|Actinobacteria,4DEVH@85008|Micromonosporales	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_881397_5	103733.JNYO01000022_gene7027	7.977e-28	115.0	COG0236@1|root,COG0236@2|Bacteria,2GQKD@201174|Actinobacteria	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR21617310_k127_881397_2	644283.Micau_3709	9.457e-132	426.0	COG0332@1|root,COG0332@2|Bacteria,2IBGC@201174|Actinobacteria,4DCAX@85008|Micromonosporales	201174|Actinobacteria	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,FAE1_CUT1_RppA
SRR21617310_k127_881397_1	644283.Micau_3708	1.467e-132	439.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DCKV@85008|Micromonosporales	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR21617310_k127_881397_3	103733.JNYO01000022_gene7024	6.574e-106	355.0	COG3319@1|root,COG3319@2|Bacteria,2I4W9@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding,Thioesterase
SRR21617310_k127_881957_8	469383.Cwoe_1045	1.724e-13	85.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR21617310_k127_881957_0	1120950.KB892749_gene3313	1.084e-220	704.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DPFV@85009|Propionibacteriales	201174|Actinobacteria	EH	TPP binding domain protein	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR21617310_k127_881957_3	1120950.KB892708_gene4177	6.322e-127	412.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DWSG@85009|Propionibacteriales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR21617310_k127_881957_1	1120950.KB892775_gene1167	2.105e-166	533.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria,4DNSK@85009|Propionibacteriales	201174|Actinobacteria	E	Membrane dipeptidase (Peptidase family M19)	Dpep	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR21617310_k127_881957_7	219305.MCAG_01039	4.784e-29	130.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,4DE8F@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR21617310_k127_881957_4	266117.Rxyl_1563	2.902e-112	377.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4CPWW@84995|Rubrobacteria	84995|Rubrobacteria	P	Major facilitator superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR21617310_k127_881957_6	652103.Rpdx1_2698	1.986e-39	156.0	28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,3JS7H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	nthB	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR21617310_k127_881957_5	1429916.X566_09720	9.72e-83	286.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3JT2X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR21617310_k127_881957_9	710686.Mycsm_04144	4.779e-12	76.0	2BATE@1|root,3248P@2|Bacteria,2HS1P@201174|Actinobacteria,23A3N@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nitrile hydratase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
SRR21617310_k127_881957_10	316274.Haur_0294	2.234e-07	52.0	COG3405@1|root,COG5297@1|root,COG3405@2|Bacteria,COG5297@2|Bacteria,2G94I@200795|Chloroflexi	200795|Chloroflexi	G	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SRR21617310_k127_881957_2	408672.NBCG_04184	3.121e-155	504.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4DQ0Z@85009|Propionibacteriales	201174|Actinobacteria	F	Amidohydrolase family	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR21617310_k127_882120_2	105425.BBPL01000002_gene6373	4.101e-57	203.0	COG5421@1|root,COG5421@2|Bacteria,2GK2A@201174|Actinobacteria,2NJVN@228398|Streptacidiphilus	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR21617310_k127_882120_4	1136417.AZWE01000077_gene272	4.151e-14	75.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	insK1	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
SRR21617310_k127_882120_0	1120949.KB903295_gene2225	2.657e-185	621.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D96C@85008|Micromonosporales	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,GerE,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR21617310_k127_882120_1	479431.Namu_0368	3.215e-79	280.0	COG0671@1|root,COG0671@2|Bacteria,2GM2U@201174|Actinobacteria,4EVAU@85013|Frankiales	201174|Actinobacteria	I	Acid phosphatase homologues	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR21617310_k127_882120_3	1068978.AMETH_3262	7.664e-37	150.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria,4E8M5@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR21617310_k127_885056_5	316274.Haur_2776	5.763e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,375U2@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR21617310_k127_885056_1	1068978.AMETH_4334	7.077e-227	727.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E2BB@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	cutL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR21617310_k127_885056_4	390989.JOEG01000005_gene1866	4.248e-50	187.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4DDW6@85008|Micromonosporales	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR21617310_k127_885056_3	28042.GU90_16810	1.718e-89	313.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4E0PT@85010|Pseudonocardiales	201174|Actinobacteria	C	carbon monoxide dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR21617310_k127_885056_0	1254432.SCE1572_30430	6.547e-238	746.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_885056_2	390989.JOEG01000003_gene4602	1.511e-118	392.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DADZ@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR21617310_k127_885056_6	222534.KB893712_gene4879	1.753e-15	87.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR21617310_k127_892172_0	937777.Deipe_0466	1.363e-41	171.0	COG3941@1|root,COG3941@2|Bacteria	2|Bacteria	O	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR21617310_k127_892172_1	1968.JOEV01000056_gene4974	3.034e-09	64.0	2AUTW@1|root,31KGY@2|Bacteria,2IKSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_892256_0	685778.AORL01000021_gene1189	1.653e-61	222.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2TS2X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	dam2	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR21617310_k127_892256_2	234267.Acid_6397	7.105e-05	46.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,RNA_ligase,tRNA_bind
SRR21617310_k127_897678_7	1041146.ATZB01000016_gene1323	2.125e-33	128.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,4B9SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR21617310_k127_897678_5	234267.Acid_4801	7.514e-45	171.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_897678_11	234267.Acid_5156	7.319e-06	55.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_897678_2	1299327.I546_0751	7.781e-89	303.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
SRR21617310_k127_897678_4	68170.KL590554_gene8421	9.704e-46	169.0	COG3293@1|root,COG3293@2|Bacteria,2IHX5@201174|Actinobacteria,4E3JT@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
SRR21617310_k127_897678_0	994479.GL877878_gene2689	7.925e-179	565.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZS1@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR21617310_k127_897678_10	278957.ABEA03000095_gene4615	6.348e-07	61.0	COG0644@1|root,COG0644@2|Bacteria,46SNN@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
SRR21617310_k127_897678_6	479432.Sros_3614	1.691e-40	159.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4EFZA@85012|Streptosporangiales	201174|Actinobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_897678_1	479432.Sros_3614	1.759e-153	492.0	COG4644@1|root,COG4644@2|Bacteria,2GNXU@201174|Actinobacteria,4EFZA@85012|Streptosporangiales	201174|Actinobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR21617310_k127_897678_8	1032480.MLP_18830	5.763e-17	90.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_897678_3	419947.MRA_2836	3.226e-88	303.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,236H8@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,Mu-transpos_C,rve
SRR21617310_k127_898509_2	1267535.KB906767_gene4332	3.774e-48	179.0	COG0494@1|root,COG0494@2|Bacteria,3Y4IG@57723|Acidobacteria	57723|Acidobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR21617310_k127_898509_4	1117108.PAALTS15_00030	5.096e-31	138.0	COG4916@1|root,COG4916@2|Bacteria,1U006@1239|Firmicutes,4I99Q@91061|Bacilli,2717X@186822|Paenibacillaceae	91061|Bacilli	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR21617310_k127_898509_0	479434.Sthe_2747	2.052e-189	606.0	COG0624@1|root,COG0624@2|Bacteria,2G62C@200795|Chloroflexi,27XWR@189775|Thermomicrobia	2|Bacteria	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR21617310_k127_898509_1	1236902.ANAS01000031_gene2800	6.124e-81	279.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4EKD3@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR21617310_k127_898509_3	28444.JODQ01000016_gene7163	3.261e-33	139.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4EJZ6@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR21617310_k127_902591_0	767817.Desgi_3832	0.0	1191.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2,LysM,PA14,PG_binding_1,Phage_lysozyme,VRP1
SRR21617310_k127_902591_1	767817.Desgi_3833	0.0	1117.0	COG2351@1|root,COG2351@2|Bacteria,1VM33@1239|Firmicutes,24X4S@186801|Clostridia	186801|Clostridia	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_902591_9	243090.RB11303	3.847e-06	53.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_902591_8	1210884.HG799464_gene10942	1.054e-07	55.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR21617310_k127_902591_6	1454010.JEOE01000035_gene1442	3.534e-19	87.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
SRR21617310_k127_902591_4	298655.KI912266_gene2476	1.97e-42	162.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_902591_2	298655.KI912266_gene2385	2.705e-47	176.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_902591_11	227882.SAV_497	8.545e-05	51.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_902591_7	543632.JOJL01000080_gene4936	5.816e-14	78.0	COG4974@1|root,COG4974@2|Bacteria,2IGA2@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR21617310_k127_902591_3	345341.KUTG_02370	1.855e-42	168.0	COG3464@1|root,COG3464@2|Bacteria,2IQ9H@201174|Actinobacteria,4EBY6@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
SRR21617310_k127_902591_10	1123226.KB899286_gene3506	2.37e-05	54.0	2EAD4@1|root,334H0@2|Bacteria,1VX7K@1239|Firmicutes,4HX6A@91061|Bacilli	91061|Bacilli	S	SUKH-4 immunity protein	-	-	-	-	-	-	-	-	-	-	-	-	SUKH-4
SRR21617310_k127_902591_5	1123508.JH636439_gene299	2.547e-20	103.0	COG1372@1|root,COG1404@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1404@2|Bacteria,COG3209@2|Bacteria,2IWU6@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,F5_F8_type_C,RHS_repeat,VCBS
SRR21617310_k127_912725_0	935866.JAER01000055_gene17	5.683e-81	281.0	28HD0@1|root,2Z7PR@2|Bacteria,2IB30@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_912725_2	211114.JOEF01000022_gene5593	2.996e-07	63.0	2A152@1|root,30PAX@2|Bacteria,2IGUI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_912725_1	365528.KB891219_gene835	1.299e-24	111.0	COG5449@1|root,COG5449@2|Bacteria	2|Bacteria	S	Phage conserved hypothetical protein BR0599	-	-	-	-	-	-	-	-	-	-	-	-	DUF2163,Phage_BR0599
SRR21617310_k127_915894_3	1463917.JODC01000021_gene9127	1.581e-115	381.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_915894_5	356851.JOAN01000001_gene3577	4.857e-82	300.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DJ2Q@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR21617310_k127_915894_4	35754.JNYJ01000035_gene3924	3.178e-88	301.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D8HK@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR21617310_k127_915894_10	35754.JNYJ01000014_gene4708	1.666e-33	134.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4DEZQ@85008|Micromonosporales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR21617310_k127_915894_6	1179773.BN6_25730	3.53e-53	191.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4E4MW@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR21617310_k127_915894_9	1449347.JQLN01000004_gene6800	6.562e-34	134.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,2M3XU@2063|Kitasatospora	201174|Actinobacteria	S	Domain of unknown function (DUF202)	yidH	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR21617310_k127_915894_12	1273538.G159_14385	1.138e-18	95.0	COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,26F3H@186818|Planococcaceae	91061|Bacilli	OP	Belongs to the sulfur carrier protein TusA family	yrkF	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
SRR21617310_k127_915894_7	1123368.AUIS01000007_gene2787	8.835e-46	171.0	COG2210@1|root,COG2210@2|Bacteria,1RCMJ@1224|Proteobacteria,1S2XA@1236|Gammaproteobacteria,2NCNX@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR21617310_k127_915894_8	1304275.C41B8_18191	4.77e-41	163.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	dmsD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR21617310_k127_915894_0	525909.Afer_1020	0.0	1516.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR21617310_k127_915894_1	1304275.C41B8_18181	5.891e-192	617.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRR21617310_k127_915894_13	518766.Rmar_0270	1.168e-15	80.0	COG0640@1|root,COG0640@2|Bacteria,4PEU3@976|Bacteroidetes,1FJM9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_915894_2	1382306.JNIM01000001_gene3601	5.508e-122	406.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G5VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR21617310_k127_915894_11	1172180.KB911775_gene6346	2.145e-29	126.0	COG0520@1|root,COG0520@2|Bacteria,2GP7W@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR21617310_k127_920381_3	1089546.AQUI01000001_gene8	4.241e-07	55.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway VirD4	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
SRR21617310_k127_920381_1	1380393.JHVP01000023_gene3278	3.568e-31	136.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	nagX	-	3.2.1.50	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF1624,DUF5009
SRR21617310_k127_920381_0	351607.Acel_0025	4.134e-183	595.0	COG3391@1|root,COG3391@2|Bacteria,2I1IX@201174|Actinobacteria,4EVVE@85013|Frankiales	2|Bacteria	S	amine dehydrogenase activity	zinT	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	-
SRR21617310_k127_920381_4	218284.CCDN010000001_gene816	8.879e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,1ZDA0@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR21617310_k127_920381_2	1001240.GY21_15235	1.824e-07	58.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FNB5@85023|Microbacteriaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR21617310_k127_925588_2	2074.JNYD01000036_gene5375	1.441e-130	439.0	COG3284@1|root,COG3284@2|Bacteria,2IANR@201174|Actinobacteria,4DZMK@85010|Pseudonocardiales	201174|Actinobacteria	KQ	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8
SRR21617310_k127_925588_0	1394178.AWOO02000028_gene5385	2.526e-198	630.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4EGVR@85012|Streptosporangiales	201174|Actinobacteria	L	DNA ligase N terminus	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR21617310_k127_925588_7	1075090.GOAMR_63_01140	1.022e-39	158.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4GBSB@85026|Gordoniaceae	201174|Actinobacteria	K	Sigma-70 region 3	sigF	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_925588_5	656024.FsymDg_2568	8.183e-62	229.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4ET2V@85013|Frankiales	201174|Actinobacteria	Q	PFAM isochorismatase hydrolase	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR21617310_k127_925588_6	1449347.JQLN01000006_gene2697	9.329e-40	167.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,2M2SE@2063|Kitasatospora	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9
SRR21617310_k127_925588_1	1283299.AUKG01000001_gene2531	4.003e-181	575.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CP6E@84995|Rubrobacteria	201174|Actinobacteria	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR21617310_k127_925588_8	869210.Marky_0355	3.879e-35	152.0	COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
SRR21617310_k127_925588_4	543632.JOJL01000014_gene9104	1.913e-69	256.0	COG2199@1|root,COG3706@2|Bacteria,2I412@201174|Actinobacteria,4DGU8@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR21617310_k127_925588_10	1463857.JOFZ01000013_gene1245	2.98e-16	93.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_925588_3	298655.KI912267_gene6903	7.054e-110	382.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_925588_9	882082.SaccyDRAFT_0843	7.286e-28	123.0	COG0791@1|root,COG0791@2|Bacteria,2I38D@201174|Actinobacteria,4DZC6@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall-associated hydrolase, invasion-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR21617310_k127_925588_11	42256.RradSPS_1884	5.17e-15	86.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR21617310_k127_92788_5	1150864.MILUP08_45153	2.329e-36	147.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4D9AC@85008|Micromonosporales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR21617310_k127_92788_6	351607.Acel_0102	8.058e-25	106.0	COG4842@1|root,COG4842@2|Bacteria,2HU2S@201174|Actinobacteria,4EWPE@85013|Frankiales	201174|Actinobacteria	S	PE family	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR21617310_k127_92788_4	345341.KUTG_00776	1.674e-61	223.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR21617310_k127_92788_0	1464048.JNZS01000014_gene3101	0.0	1364.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D8EW@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR21617310_k127_92788_2	1003195.SCAT_1309	1.927e-87	299.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR21617310_k127_92788_1	365528.KB891208_gene2837	3.545e-183	585.0	COG2268@1|root,COG2268@2|Bacteria,2GK9I@201174|Actinobacteria,4EV9R@85013|Frankiales	201174|Actinobacteria	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SRR21617310_k127_92788_7	298655.KI912266_gene5435	2.762e-21	96.0	2EF7K@1|root,3390K@2|Bacteria,2GQM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_92788_3	404589.Anae109_0474	3.471e-78	271.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR21617310_k127_928233_9	1382306.JNIM01000001_gene4039	7.705e-115	391.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR21617310_k127_928233_25	105422.BBPM01000008_gene6368	6.613e-28	133.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria,2NHH1@228398|Streptacidiphilus	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR21617310_k127_928233_11	469383.Cwoe_5866	2.164e-109	368.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR21617310_k127_928233_13	1179773.BN6_34870	9.796e-107	357.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4E0A8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR21617310_k127_928233_14	644282.Deba_2424	1.192e-103	353.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR21617310_k127_928233_20	351607.Acel_0445	5.334e-71	250.0	2B2J4@1|root,31V48@2|Bacteria,2IPFQ@201174|Actinobacteria,4EVJV@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_928233_21	861299.J421_0926	4.587e-70	246.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9
SRR21617310_k127_928233_6	35754.JNYJ01000037_gene4668	1.682e-167	563.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DBBC@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR21617310_k127_928233_7	469383.Cwoe_5384	1.959e-139	466.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria	201174|Actinobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRR21617310_k127_928233_3	351607.Acel_0683	1.841e-202	642.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria	201174|Actinobacteria	D	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_928233_2	321332.CYB_2082	2.242e-249	791.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR21617310_k127_928233_1	1125863.JAFN01000001_gene1711	1.892e-257	811.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR21617310_k127_928233_10	365528.KB891219_gene1059	8.316e-110	366.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4ERZG@85013|Frankiales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR21617310_k127_928233_8	460265.Mnod_7445	3.142e-126	423.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,1JSET@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRR21617310_k127_928233_12	309801.trd_1142	2.065e-107	368.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR21617310_k127_928233_5	479434.Sthe_2436	7.655e-188	605.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR21617310_k127_928233_24	1128421.JAGA01000002_gene1841	1.319e-29	137.0	COG3429@1|root,COG3429@2|Bacteria	2|Bacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem,PG_binding_1
SRR21617310_k127_928233_22	1089544.KB912942_gene896	1.596e-36	157.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4DXRG@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR21617310_k127_928233_17	1110502.TMO_2917	2.406e-86	304.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2TT7U@28211|Alphaproteobacteria,2JQ7G@204441|Rhodospirillales	204441|Rhodospirillales	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR21617310_k127_928233_23	1172179.AUKV01000011_gene3851	4.07e-36	147.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR21617310_k127_928233_27	1121451.DESAM_21691	5.899e-05	51.0	COG2104@1|root,COG2104@2|Bacteria,1P6X4@1224|Proteobacteria,4323S@68525|delta/epsilon subdivisions,2WXT2@28221|Deltaproteobacteria,2ME0H@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	thiamine diphosphate biosynthetic process	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
SRR21617310_k127_928233_15	1122247.C731_3324	1.625e-100	336.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR21617310_k127_928233_18	28042.GU90_06650	7.063e-77	273.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4DX8Q@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR21617310_k127_928233_0	1120936.KB907219_gene3224	2.471e-261	817.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4EHNZ@85012|Streptosporangiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR21617310_k127_928233_4	298655.KI912266_gene3656	7.874e-189	602.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4ERN8@85013|Frankiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR21617310_k127_928233_26	390989.JOEG01000007_gene613	4.479e-09	66.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria,4DFMG@85008|Micromonosporales	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR21617310_k127_928233_16	1449347.JQLN01000007_gene1162	1.503e-87	297.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,2M1JK@2063|Kitasatospora	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR21617310_k127_928233_19	671143.DAMO_0752	4.413e-72	252.0	COG0638@1|root,COG0638@2|Bacteria,2NQRX@2323|unclassified Bacteria	2|Bacteria	O	Proteasome subunit	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR21617310_k127_931424_0	1298880.AUEV01000005_gene900	4.157e-262	833.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_934760_2	448385.sce4974	4.235e-50	195.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WRC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_3,TetR_N
SRR21617310_k127_934760_0	1157637.KB892118_gene216	7.094e-179	570.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR21617310_k127_934760_1	33876.JNXY01000015_gene7460	2.366e-51	196.0	COG0242@1|root,COG0457@1|root,COG0242@2|Bacteria,COG0457@2|Bacteria,2GJT4@201174|Actinobacteria,4DA7J@85008|Micromonosporales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,Pep_deformylase
SRR21617310_k127_938874_1	298653.Franean1_0040	8.022e-88	306.0	COG4974@1|root,COG4974@2|Bacteria,2HZZ8@201174|Actinobacteria,4EV64@85013|Frankiales	201174|Actinobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_938874_2	298653.Franean1_0039	2.333e-42	164.0	COG3655@1|root,COG3655@2|Bacteria,2ISZ0@201174|Actinobacteria,4EWS9@85013|Frankiales	201174|Actinobacteria	K	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
SRR21617310_k127_938874_0	298653.Franean1_0038	4.524e-157	499.0	COG4974@1|root,COG4974@2|Bacteria,2IC5F@201174|Actinobacteria,4ETMY@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR21617310_k127_941888_0	1449347.JQLN01000004_gene6453	0.0	1242.0	COG2132@1|root,COG2132@2|Bacteria,2IDP7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
SRR21617310_k127_941888_1	1110697.NCAST_34_01860	1.095e-126	436.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4FUUF@85025|Nocardiaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR21617310_k127_941888_2	1236902.ANAS01000004_gene3788	7.155e-32	126.0	COG1309@1|root,COG1309@2|Bacteria,2IKBM@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR21617310_k127_944267_1	471852.Tcur_0134	2.534e-16	78.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4EFP1@85012|Streptosporangiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR21617310_k127_944267_2	1155714.KB891996_gene3473	2.283e-07	63.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_944267_0	196162.Noca_3776	3.581e-48	188.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR21617310_k127_946121_1	298654.FraEuI1c_7130	9.457e-116	409.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR21617310_k127_946121_5	1122611.KB903991_gene7293	5.107e-12	66.0	COG1994@1|root,COG1994@2|Bacteria,2I9PV@201174|Actinobacteria,4EPIF@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_946121_0	47763.JNZA01000004_gene3695	2.788e-232	729.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR21617310_k127_946121_4	867903.ThesuDRAFT_01341	1.406e-17	84.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR21617310_k127_946121_2	485913.Krac_10280	2.561e-54	209.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	2|Bacteria	S	PFAM alpha beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR21617310_k127_946121_3	1206732.BAGD01000081_gene3262	1.015e-44	165.0	COG2227@1|root,COG2227@2|Bacteria,2I3C3@201174|Actinobacteria,4G9T8@85025|Nocardiaceae	201174|Actinobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR21617310_k127_952074_5	1122182.KB903816_gene1696	2.457e-37	141.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DC9N@85008|Micromonosporales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR21617310_k127_952074_6	1120936.KB907220_gene1929	9.174e-33	136.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4EIYX@85012|Streptosporangiales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR21617310_k127_952074_0	1254432.SCE1572_36775	1.316e-124	419.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR21617310_k127_952074_7	477974.Daud_2046	4.559e-30	132.0	COG0295@1|root,COG0319@1|root,COG0295@2|Bacteria,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
SRR21617310_k127_952074_2	351607.Acel_0793	2.959e-102	342.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4ERS4@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR21617310_k127_952074_8	590998.Celf_3381	2.097e-09	67.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,4F1FQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR21617310_k127_952074_4	1123023.JIAI01000003_gene3073	8.752e-86	299.0	COG0451@1|root,COG0451@2|Bacteria,2HQWK@201174|Actinobacteria,4E9XH@85010|Pseudonocardiales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_952074_1	1120948.KB903243_gene2684	4.753e-105	346.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E1D6@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_952074_3	33876.JNXY01000003_gene25	7.559e-102	348.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR21617310_k127_957389_16	1496688.ER33_05105	1.196e-05	50.0	COG4089@1|root,COG4089@2|Bacteria,1G2WS@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
SRR21617310_k127_957389_8	266117.Rxyl_3168	2.849e-80	276.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4CPWT@84995|Rubrobacteria	84995|Rubrobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR21617310_k127_957389_15	1223523.H340_22811	6.015e-08	63.0	2EGCD@1|root,33A46@2|Bacteria,2IE8M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR21617310_k127_957389_5	996637.SGM_0522	3.07e-100	337.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR21617310_k127_957389_10	234267.Acid_2317	4.901e-78	282.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR21617310_k127_957389_1	1121374.KB891589_gene46	3.742e-112	374.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR21617310_k127_957389_7	670487.Ocepr_0880	2.023e-83	286.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR21617310_k127_957389_6	649638.Trad_0974	1.788e-92	311.0	COG0411@1|root,COG0411@2|Bacteria,1WJG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR21617310_k127_957389_11	1122951.ATUE01000008_gene172	4.928e-67	248.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,3NK6B@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_957389_9	1038869.AXAN01000003_gene2588	9.059e-80	279.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1K0R7@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR21617310_k127_957389_12	44060.JODL01000003_gene2814	1.475e-39	164.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR21617310_k127_957389_14	1123023.JIAI01000003_gene2566	8.156e-33	140.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR21617310_k127_957389_0	266117.Rxyl_0647	3.358e-120	396.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4CQ14@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR21617310_k127_957389_13	269800.Tfu_2625	2.497e-33	136.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR21617310_k127_957389_4	710686.Mycsm_01630	2.713e-111	370.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,235VP@1762|Mycobacteriaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR21617310_k127_957389_2	28042.GU90_09095	5.97e-112	371.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4E0UA@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfurtransferase	cysA2	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR21617310_k127_957389_3	180281.CPCC7001_519	2.694e-111	374.0	COG0524@1|root,COG0524@2|Bacteria,1G3P8@1117|Cyanobacteria,22RQ4@167375|Cyanobium	1117|Cyanobacteria	G	carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR21617310_k127_96649_4	1968.JOEV01000002_gene6931	1.355e-26	113.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_96649_7	485913.Krac_0251	4.198e-14	80.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR21617310_k127_96649_9	1449976.KALB_4674	1.601e-08	61.0	COG3335@1|root,COG3335@2|Bacteria,2HS6E@201174|Actinobacteria,4ECJZ@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR21617310_k127_96649_10	1415755.JQLV01000001_gene3742	5.128e-06	59.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,1T0G8@1236|Gammaproteobacteria,1XMAB@135619|Oceanospirillales	135619|Oceanospirillales	P	Copper-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR21617310_k127_96649_2	1229780.BN381_350095	6.066e-32	142.0	COG0526@1|root,COG0526@2|Bacteria,2H8ZP@201174|Actinobacteria	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_96649_0	1229780.BN381_350094	5.87e-33	139.0	COG1495@1|root,COG1495@2|Bacteria,2HB8T@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the DsbB family	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR21617310_k127_96649_6	1043205.AFYF01000062_gene2697	2.198e-17	92.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FES5@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent Clp protease	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_96649_5	1449353.JQMQ01000005_gene5409	7.208e-18	85.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria,2NJUX@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
SRR21617310_k127_96649_8	246194.CHY_2348	8.662e-10	70.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR21617310_k127_96649_1	1122138.AQUZ01000016_gene286	8.989e-33	138.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR21617310_k127_96649_3	298655.KI912266_gene2385	2.716e-27	114.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR21617310_k127_967140_2	1120936.KB907213_gene4837	1.757e-72	255.0	COG0484@1|root,COG0484@2|Bacteria,2GIXJ@201174|Actinobacteria,4EH8K@85012|Streptosporangiales	201174|Actinobacteria	O	Replication initiator protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_967140_5	1445613.JALM01000104_gene6259	1.827e-10	63.0	COG3311@1|root,COG3311@2|Bacteria,2GXIU@201174|Actinobacteria,4E6P6@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_967140_1	42256.RradSPS_2020	1.904e-88	319.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4CQMR@84995|Rubrobacteria	84995|Rubrobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR21617310_k127_967140_0	1386089.N865_18475	9.718e-169	548.0	COG4409@1|root,COG4409@2|Bacteria,2IEMG@201174|Actinobacteria,4FITI@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_967140_3	694431.DESACE_08930	1.815e-22	100.0	2E7HQ@1|root,33207@2|Bacteria,1NCYR@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
SRR21617310_k127_967140_4	298653.Franean1_2850	1.378e-10	69.0	COG3316@1|root,COG3316@2|Bacteria,2H0HI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR21617310_k127_974465_2	106370.Francci3_3171	1.962e-118	388.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR21617310_k127_974465_13	1122990.BAJH01000009_gene1300	3.601e-17	96.0	COG0745@1|root,COG0745@2|Bacteria,4NGNK@976|Bacteroidetes,2FNUC@200643|Bacteroidia	976|Bacteroidetes	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR21617310_k127_974465_11	1236902.ANAS01000009_gene2405	2.511e-43	179.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4EG6R@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR21617310_k127_974465_1	264732.Moth_1750	6.364e-162	539.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR21617310_k127_974465_3	1223523.H340_13132	3.086e-110	374.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR21617310_k127_974465_6	1214101.BN159_6985	1.48e-80	284.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR21617310_k127_974465_10	882083.SacmaDRAFT_3493	3.524e-44	165.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4E3EP@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR21617310_k127_974465_14	666686.B1NLA3E_17075	1.335e-10	64.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,1ZJBX@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR21617310_k127_974465_7	1246474.ANBE01000028_gene1292	1.27e-63	226.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4EGID@85012|Streptosporangiales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR21617310_k127_974465_15	479435.Kfla_5456	1.373e-06	57.0	2AI3Y@1|root,318HW@2|Bacteria,2IHSQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_974465_12	997346.HMPREF9374_2327	9.039e-24	106.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27CBV@186824|Thermoactinomycetaceae	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR21617310_k127_974465_4	351607.Acel_1270	1.033e-101	347.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4ERWR@85013|Frankiales	201174|Actinobacteria	H	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR21617310_k127_974465_9	562970.Btus_1823	1.556e-53	195.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,279P7@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR21617310_k127_974465_0	1229780.BN381_50160	1.094e-186	602.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,3UWF0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR21617310_k127_974465_8	1172181.KB911709_gene6935	1.691e-55	215.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR21617310_k127_974465_5	868595.Desca_1064	9.706e-96	328.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR21617310_k127_97469_3	926550.CLDAP_18130	1.05e-50	181.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
SRR21617310_k127_97469_5	1179773.BN6_14640	1.165e-24	110.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR21617310_k127_97469_0	1123319.AUBE01000027_gene4804	3.631e-170	547.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_97469_8	1038860.AXAP01000148_gene4490	5.633e-08	63.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR21617310_k127_97469_7	1037409.BJ6T_23800	2.912e-19	99.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR21617310_k127_97469_2	936573.HMPREF1147_1383	4.181e-75	267.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H2Z8@909932|Negativicutes	909932|Negativicutes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR21617310_k127_97469_4	479435.Kfla_6855	1.116e-47	179.0	COG2442@1|root,COG2442@2|Bacteria,2IJ8Q@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SRR21617310_k127_97469_6	479435.Kfla_6856	2.129e-21	98.0	2F5Z8@1|root,33YHS@2|Bacteria,2IPJQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_97469_9	1463856.JOHY01000007_gene565	6.283e-08	61.0	2C1KF@1|root,33IG0@2|Bacteria,2GJ79@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_97469_1	1144275.COCOR_06589	3.875e-105	355.0	COG1232@1|root,COG1232@2|Bacteria,1R7EY@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR21617310_k127_975063_2	1123320.KB889675_gene3989	1.83e-184	608.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria	201174|Actinobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR21617310_k127_975063_3	1122182.KB903839_gene1109	2.39e-181	584.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4DCFB@85008|Micromonosporales	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR21617310_k127_975063_6	351607.Acel_1503	1.902e-93	316.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4ERIQ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR21617310_k127_975063_7	1214242.B446_15775	2.423e-75	266.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_975063_5	1157637.KB892116_gene88	1.362e-95	323.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR21617310_k127_975063_0	58123.JOFJ01000023_gene3543	0.0	1875.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4EI0Q@85012|Streptosporangiales	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR21617310_k127_975063_1	1120936.KB907216_gene3853	0.0	1371.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4EHHS@85012|Streptosporangiales	201174|Actinobacteria	C	2-oxoglutarate dehydrogenase C-terminal	kgd	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR21617310_k127_975063_8	1223523.H340_00270	1.197e-28	119.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR21617310_k127_975063_4	643562.Daes_1136	2.755e-112	379.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,43A4D@68525|delta/epsilon subdivisions,2X1W9@28221|Deltaproteobacteria,2M9SN@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR21617310_k127_977122_3	1111732.AZOD01000025_gene1707	0.0005224	49.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,1X5A9@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome C	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C
SRR21617310_k127_977122_1	251221.35210711	6.426e-15	74.0	COG3039@1|root,COG3039@2|Bacteria,1G52R@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR21617310_k127_977122_2	1120797.KB908270_gene2888	8.529e-05	48.0	2C56A@1|root,323M1@2|Bacteria,2I5ZX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_977122_0	58344.JOEL01000115_gene5536	1.117e-48	175.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR21617310_k127_977531_1	1312959.KI914630_gene1702	1.29e-129	426.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,1W7TJ@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase class I and II	metC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR21617310_k127_977531_2	146922.JOFU01000040_gene1936	1.246e-125	407.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	atrC	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR21617310_k127_977531_0	263358.VAB18032_26240	2.626e-135	437.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4DAHV@85008|Micromonosporales	201174|Actinobacteria	E	ABC-type amino acid transport system, permease component	yecS	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR21617310_k127_977531_3	1380393.JHVP01000011_gene3080	7.325e-124	404.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4EV7A@85013|Frankiales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR21617310_k127_977801_1	1032480.MLP_18570	7.219e-07	55.0	COG3311@1|root,COG3311@2|Bacteria,2HUV7@201174|Actinobacteria,4DSK5@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_977801_0	1313301.AUGC01000004_gene2286	1.541e-23	112.0	COG4122@1|root,COG4122@2|Bacteria,4P7IS@976|Bacteroidetes	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR21617310_k127_977801_2	1160718.SU9_11713	1.257e-05	56.0	2B8GJ@1|root,321RP@2|Bacteria,2H5WW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_978055_0	1068980.ARVW01000001_gene7309	8.45e-153	508.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4E07J@85010|Pseudonocardiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR21617310_k127_978055_1	1380393.JHVP01000006_gene4091	1.42e-97	334.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4EVBE@85013|Frankiales	201174|Actinobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR21617310_k127_978055_3	1125863.JAFN01000001_gene2255	6.983e-24	107.0	COG0640@1|root,COG0640@2|Bacteria,1N8M7@1224|Proteobacteria,42U4R@68525|delta/epsilon subdivisions,2WQ3N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR21617310_k127_978055_2	1996.JOFO01000001_gene3680	1.139e-38	156.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4EIZ4@85012|Streptosporangiales	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR21617310_k127_978055_4	1382306.JNIM01000001_gene3267	4.26e-22	107.0	COG1359@1|root,COG1359@2|Bacteria,2G9BQ@200795|Chloroflexi	200795|Chloroflexi	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR21617310_k127_978055_5	235985.BBPN01000002_gene4878	4.922e-19	94.0	2ATXZ@1|root,31JHI@2|Bacteria,2GN21@201174|Actinobacteria,2NE9W@228398|Streptacidiphilus	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR21617310_k127_991420_0	1121926.AXWO01000004_gene1147	2.229e-63	229.0	COG1035@1|root,COG1035@2|Bacteria	2|Bacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	-	-	1.12.98.1,1.17.1.9	ko:K00125,ko:K00441	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519,R03025	RC02628,RC02796	ko00000,ko00001,ko01000	-	-	-	Big_2,Fer4,Fer4_17,FrhB_FdhB_C,PS_pyruv_trans
SRR21617310_k127_991420_1	1089546.AQUI01000002_gene1954	5.213e-08	65.0	COG3757@1|root,COG3757@2|Bacteria,2IMX7@201174|Actinobacteria	201174|Actinobacteria	M	family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,Peptidase_M23
SRR21617310_k127_993533_9	656024.FsymDg_1644	2.075e-28	123.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR21617310_k127_993533_0	1463895.JODA01000003_gene907	1.157e-234	756.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR21617310_k127_993533_6	1906.SFRA_00280	7.851e-61	240.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	atrA	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR21617310_k127_993533_2	326424.FRAAL4397	2.292e-135	464.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_993533_8	656024.FsymDg_3903	1.934e-30	124.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR21617310_k127_993533_1	1123024.AUII01000010_gene787	1.892e-176	585.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR21617310_k127_993533_7	1123023.JIAI01000010_gene8477	2.084e-41	161.0	COG2018@1|root,COG2018@2|Bacteria,2IJ6G@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR21617310_k127_993533_10	2074.JNYD01000012_gene439	1.282e-27	126.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF3489,DUF742
SRR21617310_k127_993533_5	1123024.AUII01000010_gene784	2.57e-80	271.0	COG2229@1|root,COG2229@2|Bacteria,2GM4V@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR21617310_k127_993533_3	926550.CLDAP_27340	5.328e-127	421.0	COG0154@1|root,COG0154@2|Bacteria,2G84N@200795|Chloroflexi	200795|Chloroflexi	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR21617310_k127_993533_4	47839.CCAU010000019_gene3492	7.166e-106	348.0	COG1024@1|root,COG1024@2|Bacteria,2GMNR@201174|Actinobacteria,23CNJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR21617310_k127_996604_4	103733.JNYO01000004_gene7857	3.367e-08	59.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4E6G1@85010|Pseudonocardiales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR21617310_k127_996604_0	1120936.KB907211_gene27	0.0	1026.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4EFUG@85012|Streptosporangiales	201174|Actinobacteria	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR21617310_k127_996604_1	365528.KB891219_gene1088	2.127e-39	157.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4ET14@85013|Frankiales	201174|Actinobacteria	L	helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR21617310_k127_996604_2	2045.KR76_17590	3.292e-36	156.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DP9N@85009|Propionibacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR21617310_k127_996604_3	1068980.ARVW01000001_gene363	8.221e-34	144.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4DZCD@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR21617310_k127_999771_13	1236902.ANAS01000005_gene4955	6.413e-58	220.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4EHZK@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR21617310_k127_999771_7	234267.Acid_0085	7.672e-114	391.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR21617310_k127_999771_18	479431.Namu_5014	3.819e-31	136.0	COG0515@1|root,COG0515@2|Bacteria,2IAFS@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR21617310_k127_999771_5	68570.DC74_5089	7.312e-117	386.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR21617310_k127_999771_19	1158608.I583_00948	1.508e-23	109.0	COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HJ4Q@91061|Bacilli,4B6AG@81852|Enterococcaceae	91061|Bacilli	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Endonuclea_NS_2
SRR21617310_k127_999771_16	1347086.CCBA010000007_gene4533	1.895e-36	144.0	2DNQ4@1|root,32YIU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
SRR21617310_k127_999771_2	391037.Sare_3810	4.661e-204	644.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DBAM@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR21617310_k127_999771_15	446470.Snas_5707	2.022e-44	174.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4EYET@85014|Glycomycetales	201174|Actinobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR21617310_k127_999771_17	469371.Tbis_1852	2.073e-36	155.0	2F46V@1|root,33WXW@2|Bacteria,2II56@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_999771_9	357808.RoseRS_1635	5.745e-108	358.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi,37688@32061|Chloroflexia	32061|Chloroflexia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR21617310_k127_999771_1	414996.IL38_08450	1.51e-205	644.0	COG0451@1|root,COG0451@2|Bacteria,2GJJG@201174|Actinobacteria,407XI@622450|Actinopolysporales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR21617310_k127_999771_20	882083.SacmaDRAFT_4738	1.82e-20	97.0	COG2246@1|root,COG2246@2|Bacteria,2IRFB@201174|Actinobacteria,4EEUK@85010|Pseudonocardiales	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR21617310_k127_999771_3	405948.SACE_5692	5.28e-203	671.0	COG1215@1|root,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR21617310_k127_999771_6	405948.SACE_5693	1.906e-115	380.0	COG0451@1|root,COG0451@2|Bacteria,2IAAT@201174|Actinobacteria,4DZDP@85010|Pseudonocardiales	201174|Actinobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR21617310_k127_999771_12	1120949.KB903357_gene4884	1.251e-63	234.0	COG2834@1|root,COG2834@2|Bacteria,2IIMS@201174|Actinobacteria	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_999771_8	526225.Gobs_3301	5.579e-111	370.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4ES2W@85013|Frankiales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR21617310_k127_999771_10	1380393.JHVP01000003_gene1026	5.899e-100	333.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4ESJR@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR21617310_k127_999771_21	66373.JOFQ01000001_gene1796	2.914e-08	64.0	295A0@1|root,2ZSNA@2|Bacteria,2GZBM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR21617310_k127_999771_4	2002.JOEQ01000005_gene3671	1.333e-144	473.0	COG1404@1|root,COG1404@2|Bacteria,2IBFK@201174|Actinobacteria,4EMTE@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR21617310_k127_999771_11	1122611.KB903952_gene5823	9.367e-69	244.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4EJGQ@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR21617310_k127_999771_14	1268303.RHODMAR_1597	1.359e-49	188.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria,4G8QE@85025|Nocardiaceae	201174|Actinobacteria	S	Lipase (class 2)	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2
SRR21617310_k127_999771_0	526225.Gobs_1672	9.518e-312	977.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4ERQZ@85013|Frankiales	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
## 5512 queries scanned
## Total time (seconds): 8.738261938095093
## Rate: 630.79 q/s