## Sat Dec 13 15:56:56 2025 ## emapper-2.1.13 ## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR21617311_bin.3.fa -m mmseqs --itype genome -o SRR21617311_bin.3 --output_dir /data/result/bins/wyx/egg/SRR21617311_bin.3 --cpu 32 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs SRR21617311_k127_1025026_2 1379698.RBG1_1C00001G0356 5.877e-69 244.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria 2|Bacteria EG Protein of unknown function (DUF2723) - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT SRR21617311_k127_1025026_3 1379698.RBG1_1C00001G0352 1.031e-63 242.0 COG0457@1|root,COG0457@2|Bacteria,2NRR4@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 SRR21617311_k127_1025026_0 1379698.RBG1_1C00001G0350 3.301e-180 604.0 COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - SRR21617311_k127_1025026_1 1379698.RBG1_1C00001G0347 2.28e-104 342.0 COG1657@1|root,COG1657@2|Bacteria,2NP7R@2323|unclassified Bacteria 2|Bacteria I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159,Prenyltrans SRR21617311_k127_102648_0 1379698.RBG1_1C00001G1305 2.312e-254 800.0 COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain actB - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molybdop_Fe4S4,Molydop_binding SRR21617311_k127_102648_3 1379698.RBG1_1C00001G1306 1.723e-65 228.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process actA - - ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_C552,Cytochrom_CIII,Cytochrome_C7 SRR21617311_k127_102648_5 765869.BDW_10220 0.0007487 45.0 COG2801@1|root,COG2801@2|Bacteria,1MY62@1224|Proteobacteria,42VGF@68525|delta/epsilon subdivisions,2WUY0@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_21,rve,rve_3 SRR21617311_k127_102648_2 1121918.ARWE01000001_gene3081 3.276e-95 320.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales 28221|Deltaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.1,1.2.7.7 ko:K00170,ko:K00187 ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R07160,R08034,R08566,R08567 RC00004,RC00250,RC02742,RC02833,RC02856 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C SRR21617311_k127_102648_1 1121918.ARWE01000001_gene3080 6.745e-110 368.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales 68525|delta/epsilon subdivisions C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N SRR21617311_k127_102648_4 1121918.ARWE01000001_gene3079 3.519e-22 97.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales 28221|Deltaproteobacteria E HI0933-like protein - - - - - - - - - - - - Fer4,Fer4_20,Fer4_9,Pyr_redox_2 SRR21617311_k127_1028375_0 1379698.RBG1_1C00001G0532 5.816e-190 599.0 COG0156@1|root,COG0156@2|Bacteria,2NNMX@2323|unclassified Bacteria 2|Bacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_1028375_2 1379698.RBG1_1C00001G0531 2.145e-76 269.0 COG0451@1|root,COG0451@2|Bacteria,2NPC7@2323|unclassified Bacteria 2|Bacteria GM NAD(P)H-binding JD73_00815 - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase SRR21617311_k127_1028375_1 1379698.RBG1_1C00001G0529 3.448e-113 383.0 COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria 2|Bacteria E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - Aminotran_5 SRR21617311_k127_1028375_4 1379698.RBG1_1C00001G0528 1.939e-31 131.0 COG0457@1|root,COG0457@2|Bacteria 1379698.RBG1_1C00001G0528|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SRR21617311_k127_1028375_5 1235811.HMPREF0653_01771 0.0002764 51.0 2E6R2@1|root,331B7@2|Bacteria,4NVZV@976|Bacteroidetes,2FZ1R@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_1032597_0 1541065.JRFE01000014_gene1284 3.648e-05 51.0 COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,3VJDD@52604|Pleurocapsales 1117|Cyanobacteria Q Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_1041854_1 1379698.RBG1_1C00001G0435 4.892e-44 169.0 COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria 2|Bacteria M methyltransferase greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N,SprA_N SRR21617311_k127_1041854_0 1379698.RBG1_1C00001G0436 1.318e-87 298.0 COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria 2|Bacteria S Peptidase M28 ywaD - - - - - - - - - - - Peptidase_M28 SRR21617311_k127_1041854_2 867903.ThesuDRAFT_00669 3.197e-13 75.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WDDX@538999|Clostridiales incertae sedis 186801|Clostridia L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB SRR21617311_k127_1050099_1 1162668.LFE_2449 9.931e-12 68.0 COG2109@1|root,COG2109@2|Bacteria,3J0NJ@40117|Nitrospirae 40117|Nitrospirae H ATP:corrinoid adenosyltransferase BtuR/CobO/CobP - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - CobA_CobO_BtuR SRR21617311_k127_1050099_0 330214.NIDE2638 3.748e-145 481.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,3J0ZS@40117|Nitrospirae 40117|Nitrospirae C FAD linked oxidases, C-terminal domain - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 SRR21617311_k127_1055885_0 1379698.RBG1_1C00001G1165 0.0 1044.0 COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_2300 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SRR21617311_k127_1059609_0 243231.GSU0686 5.197e-122 401.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C SRR21617311_k127_1059609_1 1379698.RBG1_1C00001G1130 3.462e-71 258.0 COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria 2|Bacteria G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 NAD_kinase SRR21617311_k127_1059609_2 289376.THEYE_A0140 6.82e-56 205.0 COG0744@1|root,COG0744@2|Bacteria,3J127@40117|Nitrospirae 40117|Nitrospirae M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly SRR21617311_k127_1064517_0 1379698.RBG1_1C00001G1427 9.534e-77 264.0 COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria 2|Bacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C SRR21617311_k127_1064517_1 330214.NIDE0992 9.917e-66 231.0 COG1039@1|root,COG1039@2|Bacteria 2|Bacteria L RNA-DNA hybrid ribonuclease activity rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII SRR21617311_k127_1064517_2 326427.Cagg_2012 5.268e-26 120.0 COG1184@1|root,COG1184@2|Bacteria,2G9CC@200795|Chloroflexi,3762Q@32061|Chloroflexia 32061|Chloroflexia J Belongs to the eIF-2B alpha beta delta subunits family - - - ko:K03680 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - IF-2B SRR21617311_k127_1067007_1 1379698.RBG1_1C00001G0596 7.07e-36 141.0 COG0265@1|root,COG0265@2|Bacteria,2NQK9@2323|unclassified Bacteria 2|Bacteria O Trypsin degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR21617311_k127_1067007_0 1379698.RBG1_1C00001G0597 8.876e-85 290.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR21617311_k127_1067501_1 1379698.RBG1_1C00001G0743 7.716e-67 231.0 COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria 2|Bacteria S DinB superfamily dinB - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - DinB SRR21617311_k127_1067501_0 555079.Toce_1766 2.291e-157 507.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales 186801|Clostridia O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX SRR21617311_k127_1067501_3 266117.Rxyl_0907 2.075e-22 102.0 COG2259@1|root,COG2259@2|Bacteria,2HP7E@201174|Actinobacteria,4CQJN@84995|Rubrobacteria 84995|Rubrobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SRR21617311_k127_1067501_2 1379698.RBG1_1C00001G1713 1.792e-34 134.0 COG0218@1|root,COG0218@2|Bacteria,2NPMT@2323|unclassified Bacteria 2|Bacteria D Necessary for normal cell division and for the maintenance of normal septation engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 SRR21617311_k127_1069793_1 42256.RradSPS_2704 1.138e-42 162.0 COG0438@1|root,COG0438@2|Bacteria,2ID3T@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 SRR21617311_k127_1069793_0 1229172.JQFA01000002_gene2794 2.061e-104 361.0 COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales 1117|Cyanobacteria V ABC-type multidrug transport system ATPase and permease - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SRR21617311_k127_1087988_0 1397528.Q671_16195 4.766e-107 355.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XHSS@135619|Oceanospirillales 135619|Oceanospirillales V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_1087988_1 1121920.AUAU01000004_gene687 3.171e-83 291.0 COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria 57723|Acidobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SRR21617311_k127_1087988_2 1047013.AQSP01000139_gene2334 1.715e-38 151.0 COG0842@1|root,COG0842@2|Bacteria,2NPA6@2323|unclassified Bacteria 2|Bacteria V ABC-type multidrug transport system, permease component ybhR - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SRR21617311_k127_1088092_3 1379698.RBG1_1C00001G1360 2.822e-97 328.0 COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria 2|Bacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SRR21617311_k127_1088092_0 1201290.M902_3137 3.545e-124 405.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2MSKZ@213481|Bdellovibrionales,2WKJ6@28221|Deltaproteobacteria 213481|Bdellovibrionales G TIGRFAM fructose-1,6-bisphosphatase, class II glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX SRR21617311_k127_1088092_5 1379698.RBG1_1C00001G0551 2.261e-37 144.0 COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD SRR21617311_k127_1088092_1 1379698.RBG1_1C00001G0551 1.286e-116 385.0 COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD SRR21617311_k127_1088092_2 1379698.RBG1_1C00001G0549 2.365e-108 355.0 COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria 2|Bacteria S lipopolysaccharide transport protein B ATP-binding component of ABC superfamily lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 - - ABC_tran,BCA_ABC_TP_C SRR21617311_k127_1088092_4 330214.NIDE3631 6.708e-47 174.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH,HNH_5 SRR21617311_k127_1101332_1 1519464.HY22_10300 6.875e-65 241.0 COG1596@1|root,COG1596@2|Bacteria 2|Bacteria M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB SRR21617311_k127_1101332_2 483219.LILAB_20310 1.67e-05 58.0 COG0457@1|root,COG0457@2|Bacteria,1QX7S@1224|Proteobacteria,43C0S@68525|delta/epsilon subdivisions,2X7BD@28221|Deltaproteobacteria,2YV1Y@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_1101332_0 1379698.RBG1_1C00001G0205 2.684e-87 292.0 COG0648@1|root,COG0648@2|Bacteria,2NNN3@2323|unclassified Bacteria 2|Bacteria L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 SRR21617311_k127_1103779_1 1379698.RBG1_1C00001G0768 1.425e-103 345.0 COG3005@1|root,COG3005@2|Bacteria,2NQ90@2323|unclassified Bacteria 2|Bacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - ko:K08354 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko02000 5.A.3.5 - - Cytochrome_C554,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1 SRR21617311_k127_1103779_0 1379698.RBG1_1C00001G0769 2.434e-134 456.0 COG3637@1|root,COG3637@2|Bacteria,2NQC8@2323|unclassified Bacteria 2|Bacteria M Putative outer membrane beta-barrel porin, MtrB/PioB - - - ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2 - - MtrB_PioB,OMP_b-brl,OMP_b-brl_2 SRR21617311_k127_1104891_0 1379698.RBG1_1C00001G1209 2.438e-88 310.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - DUF2723,PMT_2 SRR21617311_k127_1104891_1 1379698.RBG1_1C00001G1208 3.321e-30 126.0 COG4969@1|root,COG4969@2|Bacteria 2|Bacteria NU cell adhesion mshB - - ko:K02456,ko:K02650,ko:K10924,ko:K10925 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - N_methyl,Pilin,T2SSG SRR21617311_k127_1104891_2 1379698.RBG1_1C00001G1208 6.971e-30 122.0 COG4969@1|root,COG4969@2|Bacteria 2|Bacteria NU cell adhesion mshB - - ko:K02456,ko:K02650,ko:K10924,ko:K10925 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - N_methyl,Pilin,T2SSG SRR21617311_k127_1108468_0 1379698.RBG1_1C00001G1272 8.507e-67 235.0 COG0500@1|root,COG2226@2|Bacteria,2NPGE@2323|unclassified Bacteria 2|Bacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran SRR21617311_k127_1108468_1 391612.CY0110_22986 3.749e-28 123.0 COG2866@1|root,COG2866@2|Bacteria,1G1CQ@1117|Cyanobacteria,3KGU0@43988|Cyanothece 1117|Cyanobacteria E PFAM peptidase M14 carboxypeptidase A - - - - - - - - - - - - Peptidase_M14 SRR21617311_k127_110875_14 1379698.RBG1_1C00001G1054 1.699e-30 124.0 COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria 2|Bacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx SRR21617311_k127_110875_1 1379698.RBG1_1C00001G1053 2.391e-186 588.0 COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa SRR21617311_k127_110875_9 1379698.RBG1_1C00001G1052 2.232e-62 218.0 COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iAF987.Gmet_3353 Complex1_30kDa SRR21617311_k127_110875_7 1379698.RBG1_1C00001G1051 7.326e-74 256.0 COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 SRR21617311_k127_110875_13 1379698.RBG1_1C00001G1050 2.053e-40 152.0 COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 SRR21617311_k127_110875_0 1379698.RBG1_1C00001G1048 0.0 1011.0 COG1205@1|root,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria 2|Bacteria L Domain of unknown function (DUF1998) yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C SRR21617311_k127_110875_5 485913.Krac_3424 1.16e-99 338.0 COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi 200795|Chloroflexi I PFAM Fatty acid desaturase - - - - - - - - - - - - FA_desaturase SRR21617311_k127_110875_10 1379698.RBG1_1C00001G1047 4.317e-60 212.0 COG1913@1|root,COG1913@2|Bacteria 2|Bacteria S metallopeptidase activity - - - ko:K06974 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M54 SRR21617311_k127_110875_6 1379698.RBG1_1C00001G1046 7.403e-78 271.0 COG1940@1|root,COG1940@2|Bacteria,2NPRP@2323|unclassified Bacteria 2|Bacteria GK ROK family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK SRR21617311_k127_110875_2 1379698.RBG1_1C00001G1045 1.059e-152 501.0 COG0436@1|root,COG0436@2|Bacteria,2NP0E@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS10450 Aminotran_1_2 SRR21617311_k127_110875_15 1379698.RBG1_1C00001G1769 4.516e-19 91.0 COG0640@1|root,COG0640@2|Bacteria,2NQ1G@2323|unclassified Bacteria 2|Bacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5 SRR21617311_k127_110875_4 331678.Cphamn1_0759 3.551e-116 385.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase arsM - 2.1.1.137,2.1.1.79 ko:K00574,ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 SRR21617311_k127_110875_3 1173028.ANKO01000244_gene3949 9.735e-117 381.0 COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales 1117|Cyanobacteria S Phenazine biosynthesis protein - - - - - - - - - - - - PhzC-PhzF SRR21617311_k127_110875_8 1379698.RBG1_1C00001G1043 1.943e-63 230.0 COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase, family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_110875_11 1232410.KI421428_gene1070 3.019e-53 198.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,43T9F@69541|Desulfuromonadales 28221|Deltaproteobacteria V Bacitracin resistance protein BacA uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA SRR21617311_k127_1111529_0 1379698.RBG1_1C00001G0237 5.668e-95 328.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Calx-beta,LVIVD SRR21617311_k127_1111529_1 1449126.JQKL01000036_gene1950 8.002e-58 226.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_1113876_0 1379698.RBG1_1C00001G0844 3.027e-172 549.0 COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c DALR_2,tRNA-synt_1e,tRNA-synt_1g SRR21617311_k127_1113876_3 1379698.RBG1_1C00001G1091 4.338e-37 154.0 COG0823@1|root,COG2911@1|root,COG0823@2|Bacteria,COG2911@2|Bacteria,2NS5I@2323|unclassified Bacteria 2|Bacteria U FlgD Ig-like domain - - - ko:K13669 - - - - ko00000,ko01000,ko01003 - GT87 - CBM_6,Cellulase,FlgD_ig,GT87,PD40,VCBS SRR21617311_k127_1113876_4 880073.Calab_2081 1.508e-19 101.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD SRR21617311_k127_1113876_2 1379698.RBG1_1C00001G1196 5.054e-39 151.0 COG1371@1|root,COG1371@2|Bacteria,2NPX9@2323|unclassified Bacteria 2|Bacteria S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease SRR21617311_k127_1113876_1 1379698.RBG1_1C00001G1195 3.158e-66 231.0 COG1690@1|root,COG1690@2|Bacteria,2NNVX@2323|unclassified Bacteria 2|Bacteria S Belongs to the RtcB family rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB SRR21617311_k127_1123598_0 1379698.RBG1_1C00001G0119 8.958e-118 386.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_1123598_1 1379698.RBG1_1C00001G0118 2.632e-46 170.0 29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1130206_0 1379698.RBG1_1C00001G0824 1.341e-180 585.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR_2,CBM_35,DUF1080,PKD SRR21617311_k127_1130206_4 1521187.JPIM01000002_gene3187 4.969e-05 53.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia 32061|Chloroflexia K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_1130206_1 861299.J421_0867 4.8e-64 244.0 COG0515@1|root,COG0515@2|Bacteria 861299.J421_0867|- KLT protein kinase activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - - SRR21617311_k127_1130206_2 1379698.RBG1_1C00001G0634 1.768e-62 222.0 COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria 2|Bacteria F NUDIX domain - - - - - - - - - - - - NUDIX,Nudix_N_2 SRR21617311_k127_1130206_3 1379698.RBG1_1C00001G1345 8.914e-62 237.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - GAF,GAF_2,HATPase_c_2,SSF,SpoIIE SRR21617311_k127_1134769_1 1379698.RBG1_1C00001G0583 4.658e-121 416.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - ASH,Cohesin,FlgD_ig,Peptidase_S74 SRR21617311_k127_1134769_0 1379698.RBG1_1C00001G0584 9.325e-156 504.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL SRR21617311_k127_1135974_0 945713.IALB_1644 9.29e-167 554.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec SRR21617311_k127_1137223_1 1227266.HMPREF1551_01388 6.351e-34 135.0 COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia,1ER7D@1016|Capnocytophaga 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N SRR21617311_k127_1137223_0 1379698.RBG1_1C00001G1432 2.091e-84 299.0 COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria 2|Bacteria D Required for chromosome condensation and partitioning smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03529,ko:K19171 - - - - ko00000,ko02048,ko03036 - - - SMC_N,SMC_hinge SRR21617311_k127_1144552_1 1379698.RBG1_1C00001G0407 2.409e-163 524.0 COG0823@1|root,COG0823@2|Bacteria,2NQA4@2323|unclassified Bacteria 2|Bacteria U Periplasmic component of the Tol biopolymer transport system tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PA,PD40,PDZ_2,Peptidase_M28 SRR21617311_k127_1144552_0 880073.Calab_0163 7.416e-181 582.0 COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria 2|Bacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small SRR21617311_k127_1144552_2 1379698.RBG1_1C00001G1194 6.913e-156 548.0 COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - 3.2.1.91 ko:K14194,ko:K19668 ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CHU_C,DUF11,FlgD_ig,PKD,SdrD_B SRR21617311_k127_1144989_2 986075.CathTA2_1870 2.714e-84 288.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT SRR21617311_k127_1144989_10 653733.Selin_2568 7.818e-22 99.0 COG1837@1|root,COG1837@2|Bacteria 2|Bacteria L Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 SRR21617311_k127_1144989_8 1379698.RBG1_1C00001G0947 1.089e-29 126.0 COG0228@1|root,COG0228@2|Bacteria,2NPWN@2323|unclassified Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 SRR21617311_k127_1144989_1 429009.Adeg_1417 3.696e-142 465.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales 186801|Clostridia U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB SRR21617311_k127_1144989_3 1121346.KB899808_gene3385 8.768e-71 246.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim SRR21617311_k127_1144989_7 1379698.RBG1_1C00001G0942 2.867e-39 157.0 COG2815@1|root,COG2815@2|Bacteria,2NPV8@2323|unclassified Bacteria 2|Bacteria S PASTA prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase SRR21617311_k127_1144989_5 1379698.RBG1_1C00001G0179 1.606e-41 171.0 COG0065@1|root,COG0065@2|Bacteria 2|Bacteria E 3-isopropylmalate dehydratase activity - - 4.2.1.33,4.2.1.35,4.2.1.36 ko:K01703,ko:K01705 ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230 M00030,M00432,M00433,M00535 R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR21617311_k127_1144989_4 760568.Desku_2804 5.103e-54 195.0 COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,24HFR@186801|Clostridia,266WR@186807|Peptococcaceae 186801|Clostridia FG Scavenger mRNA decapping enzyme C-term binding - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT SRR21617311_k127_1144989_11 401526.TcarDRAFT_1987 5.139e-21 109.0 COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes 909932|Negativicutes L AAA domain - - - - - - - - - - - - AAA_23,AAA_27 SRR21617311_k127_1144989_12 1514668.JOOA01000001_gene396 1.32e-15 89.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3WHWS@541000|Ruminococcaceae 186801|Clostridia L Calcineurin-like phosphoesterase superfamily domain - - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos SRR21617311_k127_1144989_14 309807.SRU_2180 0.0004571 53.0 COG0457@1|root,COG0457@2|Bacteria,4PEIW@976|Bacteroidetes,1FJ6Z@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_1144989_0 1047013.AQSP01000105_gene1461 1.251e-151 514.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site dap2 - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 SRR21617311_k127_1144989_9 1047013.AQSP01000115_gene356 3.928e-22 111.0 COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria 2|Bacteria E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS06550 Aminotran_1_2 SRR21617311_k127_1144989_13 1379698.RBG1_1C00001G0536 9.953e-05 48.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SRR21617311_k127_1151578_0 1379698.RBG1_1C00001G1430 2.141e-102 340.0 COG0552@1|root,COG0552@2|Bacteria,2NP66@2323|unclassified Bacteria 2|Bacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N SRR21617311_k127_1151578_2 477974.Daud_0826 2.321e-42 162.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,2629H@186807|Peptococcaceae 186801|Clostridia S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SRR21617311_k127_1151578_1 290397.Adeh_0617 1.722e-101 338.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales 28221|Deltaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis pdp - 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C SRR21617311_k127_1151578_3 1379698.RBG1_1C00001G1563 1.972e-31 126.0 COG0213@1|root,COG0213@2|Bacteria,2NNXJ@2323|unclassified Bacteria 2|Bacteria F Pyrimidine nucleoside phosphorylase C-terminal domain pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS08925 Glycos_trans_3N,Glycos_transf_3,PYNP_C SRR21617311_k127_1152471_1 1379698.RBG1_1C00001G1237 4.765e-06 50.0 COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains zraR GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1152471_0 1379698.RBG1_1C00001G1238 5.483e-146 482.0 COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria 2|Bacteria T COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1 SRR21617311_k127_1154118_0 760192.Halhy_5603 2.632e-35 156.0 COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes 976|Bacteroidetes E regulator of chromosome condensation, RCC1 - - - - - - - - - - - - CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3 SRR21617311_k127_1154118_1 1347369.CCAD010000078_gene2943 7.209e-15 86.0 COG0823@1|root,COG0823@2|Bacteria,1UA2G@1239|Firmicutes 1239|Firmicutes U Periplasmic component of the Tol biopolymer transport system - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SRR21617311_k127_1154343_0 1379698.RBG1_1C00001G0435 4.058e-206 676.0 COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria 2|Bacteria M methyltransferase greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N,SprA_N SRR21617311_k127_1172510_2 497964.CfE428DRAFT_1025 1.814e-41 156.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - 2.1.1.331,2.1.1.332 ko:K13601,ko:K13602 ko00860,ko01110,map00860,map01110 - R11507,R11508,R11509 RC03457,RC03458,RC03459 ko00000,ko00001,ko01000 - - - B12-binding,DUF4070,Radical_SAM SRR21617311_k127_1172510_3 497964.CfE428DRAFT_1024 2.448e-33 132.0 2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - SRR21617311_k127_1172510_0 1123386.AUIW01000010_gene96 6.961e-177 564.0 COG0427@1|root,COG0427@2|Bacteria,1WJIT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro SRR21617311_k127_1172510_1 309799.DICTH_0907 1.256e-94 322.0 COG0686@1|root,COG0686@2|Bacteria 2|Bacteria E alanine dehydrogenase activity ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - iAF987.Gmet_1099 AlaDh_PNT_C,AlaDh_PNT_N SRR21617311_k127_1172510_4 1379698.RBG1_1C00001G0517 1.084e-16 79.0 COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria 2|Bacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SRR21617311_k127_1172724_0 1379698.RBG1_1C00001G0175 2.099e-173 569.0 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,2NRE7@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02022,ko:K16922,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko01002,ko02000 3.A.1.112,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD SRR21617311_k127_1172724_6 1191523.MROS_0472 3.975e-23 111.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - C_GCAxxG_C_C,FlgD_ig,Peptidase_S74 SRR21617311_k127_1172724_1 1347087.CBYO010000004_gene372 5.543e-63 222.0 COG4312@1|root,COG4312@2|Bacteria,1UYI5@1239|Firmicutes,4HF86@91061|Bacilli 91061|Bacilli S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 SRR21617311_k127_1172724_4 1396418.BATQ01000144_gene3442 1.029e-32 136.0 COG3832@1|root,COG3832@2|Bacteria,46XRK@74201|Verrucomicrobia,2IWFC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SRR21617311_k127_1172724_2 391625.PPSIR1_19974 2.96e-35 137.0 COG3070@1|root,COG3070@2|Bacteria,1QEQQ@1224|Proteobacteria,4318J@68525|delta/epsilon subdivisions,2WWGX@28221|Deltaproteobacteria 28221|Deltaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N SRR21617311_k127_1172724_3 1205680.CAKO01000029_gene5240 2.04e-34 133.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S RNA signal recognition particle 4.5S RNA - - - - - - - - - - - - DUF1428 SRR21617311_k127_1176896_4 1379698.RBG1_1C00001G0765 1.567e-15 79.0 COG2132@1|root,COG2132@2|Bacteria,2NPCW@2323|unclassified Bacteria 2|Bacteria PQ Multicopper oxidase aniA - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 SRR21617311_k127_1176896_1 204669.Acid345_0435 1.633e-63 226.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c moxG - - ko:K00406,ko:K16255 ko00190,ko00680,ko01100,ko01120,ko02020,map00190,map00680,map01100,map01120,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3 SRR21617311_k127_1176896_2 330214.NIDE3793 8.952e-53 203.0 29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae 40117|Nitrospirae - - - - - - - - - - - - - - - SRR21617311_k127_1176896_0 1379698.RBG1_1C00001G0005 5.156e-84 285.0 COG3794@1|root,COG3794@2|Bacteria,2NR3M@2323|unclassified Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - CarboxypepD_reg,fn3_3 SRR21617311_k127_1176896_3 1379698.RBG1_1C00001G0345 4.928e-44 164.0 COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SRR21617311_k127_1184192_1 1379698.RBG1_1C00001G0098 8.72e-33 132.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - - - - - - - - - - Response_reg SRR21617311_k127_1184192_0 502558.EGYY_14060 1.167e-34 138.0 COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CUJD@84998|Coriobacteriia 84998|Coriobacteriia S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 SRR21617311_k127_1187400_0 1379698.RBG1_1C00001G0659 6.175e-289 899.0 COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SRR21617311_k127_1191167_0 1379698.RBG1_1C00001G0940 1.368e-76 272.0 COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,2NNKI@2323|unclassified Bacteria 2|Bacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - DUF2344,Radical_SAM SRR21617311_k127_1191167_1 1379698.RBG1_1C00001G0941 2.309e-37 149.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2NP36@2323|unclassified Bacteria 2|Bacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB SRR21617311_k127_1192773_0 1379698.RBG1_1C00001G0399 4.978e-69 243.0 COG0849@1|root,COG0849@2|Bacteria,2NNU2@2323|unclassified Bacteria 2|Bacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SRR21617311_k127_1192773_1 1203622.HMPREF1290_01338 0.0006819 50.0 COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,22MQI@1653|Corynebacteriaceae 201174|Actinobacteria D Cell division protein FtsQ ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 SRR21617311_k127_1195771_0 234267.Acid_6173 3.375e-165 523.0 COG1741@1|root,COG1741@2|Bacteria,3Y367@57723|Acidobacteria 57723|Acidobacteria S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C SRR21617311_k127_1217818_0 1379698.RBG1_1C00001G0646 0.0 1140.0 COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria 2|Bacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C SRR21617311_k127_1217818_7 1379698.RBG1_1C00001G0647 2.336e-33 134.0 COG0071@1|root,COG0071@2|Bacteria,2NRQT@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family MA20_45160 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SRR21617311_k127_1217818_2 1379698.RBG1_1C00001G0197 7.218e-88 298.0 COG1521@1|root,COG1521@2|Bacteria,2NP3Z@2323|unclassified Bacteria 2|Bacteria K Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1986 Pan_kinase SRR21617311_k127_1217818_10 204669.Acid345_4467 2.063e-22 112.0 COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia 204432|Acidobacteriia KT Peptidase M56 - - - - - - - - - - - - - SRR21617311_k127_1217818_11 666686.B1NLA3E_10620 8.215e-06 55.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus 91061|Bacilli CO COG0526 Thiol-disulfide isomerase and thioredoxins stoA - - - - - - - - - - - AhpC-TSA SRR21617311_k127_1217818_5 1297742.A176_02723 6.272e-62 237.0 COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales 28221|Deltaproteobacteria M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT_2,Pro_isomerase SRR21617311_k127_1217818_3 65393.PCC7424_2030 5.451e-70 240.0 COG1839@1|root,COG1839@2|Bacteria,1G575@1117|Cyanobacteria,3KHP9@43988|Cyanothece 1117|Cyanobacteria S Adenosine specific kinase - - - ko:K09129 - - - - ko00000 - - - Adenosine_kin SRR21617311_k127_1217818_8 459349.CLOAM1429 6.838e-28 117.0 29XH8@1|root,30J7X@2|Bacteria,2NS24@2323|unclassified Bacteria 2|Bacteria J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP SRR21617311_k127_1217818_4 1278073.MYSTI_06533 1.226e-69 250.0 COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,433WA@68525|delta/epsilon subdivisions,2X3U0@28221|Deltaproteobacteria,2YX3S@29|Myxococcales 28221|Deltaproteobacteria J Exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07577 - - - - ko00000 - - - - SRR21617311_k127_1217818_1 1379698.RBG1_1C00001G1339 7.176e-226 717.0 COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria 2|Bacteria S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT SRR21617311_k127_1217818_9 1379698.RBG1_1C00001G0468 2.683e-26 114.0 COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria 2|Bacteria S DinB family yrdA - - - - - - - - - - - DinB SRR21617311_k127_1217818_6 1254432.SCE1572_41005 5.763e-56 208.0 COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,1RB92@1224|Proteobacteria,43CMY@68525|delta/epsilon subdivisions,2X7V4@28221|Deltaproteobacteria,2YXBK@29|Myxococcales 28221|Deltaproteobacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS SRR21617311_k127_1224777_1 1051632.TPY_2938 1.594e-110 366.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,2497I@186801|Clostridia 186801|Clostridia E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 SRR21617311_k127_1224777_3 552811.Dehly_1325 1.443e-22 100.0 COG3339@1|root,COG3339@2|Bacteria,2G7DT@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 SRR21617311_k127_1224777_4 479431.Namu_0997 0.0006569 51.0 COG3832@1|root,COG3832@2|Bacteria,2IP40@201174|Actinobacteria 201174|Actinobacteria J glyoxalase III activity - - - - - - - - - - - - - SRR21617311_k127_1224777_2 1379698.RBG1_1C00001G1221 3.758e-104 352.0 COG0620@1|root,COG0620@2|Bacteria 2|Bacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 SRR21617311_k127_1224777_0 1120972.AUMH01000010_gene394 1.235e-126 417.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,2784T@186823|Alicyclobacillaceae 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt SRR21617311_k127_1236191_1 1500890.JQNL01000001_gene1464 2.458e-10 66.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS SRR21617311_k127_1236191_0 1379698.RBG1_1C00001G0971 1.401e-119 392.0 COG0152@1|root,COG0152@2|Bacteria,2NP0V@2323|unclassified Bacteria 2|Bacteria F SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 - - - SAICAR_synt SRR21617311_k127_1238307_0 1379698.RBG1_1C00001G0380 2.28e-107 360.0 COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria 2|Bacteria M Carbon-nitrogen hydrolase lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SRR21617311_k127_1238307_1 1379698.RBG1_1C00001G0381 1.254e-100 354.0 COG3292@1|root,COG3292@2|Bacteria,2NR3S@2323|unclassified Bacteria 2|Bacteria T Two component regulator propeller - - - - - - - - - - - - Reg_prop SRR21617311_k127_1243654_0 1379698.RBG1_1C00001G0341 2.517e-114 375.0 COG0766@1|root,COG0766@2|Bacteria,2NNUV@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase SRR21617311_k127_1243654_1 1379698.RBG1_1C00001G0342 1.904e-66 235.0 COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria 2|Bacteria S Calcineurin-like phosphoesterase lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - iE2348C_1286.E2348C_0457 Metallophos,Metallophos_2 SRR21617311_k127_1248257_3 32057.KB217480_gene7997 2.43e-25 111.0 COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales 1117|Cyanobacteria KLT PFAM KWG Leptospira - - - - - - - - - - - - SLH,WG_beta_rep SRR21617311_k127_1248257_0 1379698.RBG1_1C00001G0201 1.132e-157 503.0 COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria 2|Bacteria O ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SRR21617311_k127_1248257_2 1379698.RBG1_1C00001G0814 7.72e-43 160.0 COG0454@1|root,COG0456@2|Bacteria,2NRWK@2323|unclassified Bacteria 2|Bacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 SRR21617311_k127_1248257_1 1379698.RBG1_1C00001G0202 2.961e-108 355.0 COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SRR21617311_k127_1266098_3 517418.Ctha_1221 1.374e-12 74.0 2ECQK@1|root,336N8@2|Bacteria,1FEWY@1090|Chlorobi 1090|Chlorobi S Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi SRR21617311_k127_1266098_1 518766.Rmar_2753 1.433e-100 336.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 SRR21617311_k127_1266098_0 1047013.AQSP01000114_gene683 8.48e-208 654.0 COG0286@1|root,COG0286@2|Bacteria,2NQG4@2323|unclassified Bacteria 2|Bacteria V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase SRR21617311_k127_1272079_0 1379698.RBG1_1C00001G1545 2.678e-220 694.0 COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria 2|Bacteria KT PglZ domain - - - - - - - - - - - - PglZ,Response_reg SRR21617311_k127_1272079_2 1379698.RBG1_1C00001G1546 1.791e-41 157.0 COG0802@1|root,COG0802@2|Bacteria,2NPU4@2323|unclassified Bacteria 2|Bacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE yjeE - 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 - - - TsaE SRR21617311_k127_1272079_3 498761.HM1_1718 3.886e-28 123.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia 186801|Clostridia O Universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Acetyltransf_1,Peptidase_M22 SRR21617311_k127_1272079_4 1410624.JNKK01000006_gene1931 2.757e-23 106.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,27PG8@186928|unclassified Lachnospiraceae 186801|Clostridia K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 SRR21617311_k127_1272079_1 1379698.RBG1_1C00001G1549 1.425e-119 389.0 COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans SRR21617311_k127_128770_1 1122603.ATVI01000005_gene3501 7.629e-14 81.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SZ6C@1236|Gammaproteobacteria,1XCCV@135614|Xanthomonadales 1236|Gammaproteobacteria T Tetratricopeptide repeat - - - - - - - - - - - - Guanylate_cyc,TPR_19,TPR_2,TPR_8 SRR21617311_k127_128770_0 1121085.AUCI01000005_gene919 1.544e-84 287.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_128798_1 1379698.RBG1_1C00001G1534 7.376e-78 267.0 COG0018@1|root,COG0018@2|Bacteria,2NP0H@2323|unclassified Bacteria 2|Bacteria J Arginyl tRNA synthetase N terminal dom argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_1434,iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR21617311_k127_128798_2 370438.PTH_1623 6.98e-60 218.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,261HU@186807|Peptococcaceae 186801|Clostridia E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA SRR21617311_k127_128798_0 246194.CHY_1582 1.051e-161 516.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,42EWK@68295|Thermoanaerobacterales 186801|Clostridia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR21617311_k127_1291995_1 1385935.N836_32445 5.958e-24 109.0 2ER3Y@1|root,33IPI@2|Bacteria,1GCZW@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_1291995_0 1379698.RBG1_1C00001G1740 1.997e-134 449.0 COG3852@1|root,COG3852@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9 SRR21617311_k127_1293196_1 1379698.RBG1_1C00001G1318 1.365e-12 70.0 COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria 2|Bacteria S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SRR21617311_k127_1293196_0 1379698.RBG1_1C00001G1319 5.093e-118 386.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1302387_0 1121468.AUBR01000026_gene2957 8.386e-155 499.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42FJ7@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 SRR21617311_k127_1302387_1 1191523.MROS_1726 1.094e-73 252.0 COG0176@1|root,COG0176@2|Bacteria 2|Bacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA SRR21617311_k127_1302402_4 1232410.KI421418_gene2291 5.074e-75 263.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43S1F@69541|Desulfuromonadales 28221|Deltaproteobacteria E Semialdehyde dehydrogenase, NAD binding domain argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC SRR21617311_k127_1302402_5 1382359.JIAL01000001_gene2596 2.159e-47 180.0 COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria,2JIE8@204432|Acidobacteriia 204432|Acidobacteriia E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase SRR21617311_k127_1302402_3 720554.Clocl_0490 1.63e-99 338.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae 186801|Clostridia E acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SRR21617311_k127_1302402_0 309801.trd_A0866 3.271e-160 517.0 COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,27XN0@189775|Thermomicrobia 189775|Thermomicrobia E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth SRR21617311_k127_1302402_1 1216007.AOPM01000002_gene2564 8.328e-117 397.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,2Q0IQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E belongs to the lyase 1 family. Argininosuccinate lyase subfamily argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K01755,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844,M00845 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Acetyltransf_1,Lyase_1 SRR21617311_k127_1302402_2 429009.Adeg_1832 4.713e-102 347.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,42F14@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ SRR21617311_k127_1312343_2 1379698.RBG1_1C00001G1782 3.863e-44 172.0 COG4775@1|root,COG4775@2|Bacteria,2NPNI@2323|unclassified Bacteria 2|Bacteria M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SRR21617311_k127_1312343_1 1379698.RBG1_1C00001G1781 1.613e-48 183.0 COG0382@1|root,COG0382@2|Bacteria,2NQZV@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family ubiA - 2.5.1.39,2.5.1.42 ko:K03179,ko:K17105 ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110 M00117 R04520,R05000,R05615 RC00209,RC01171,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA SRR21617311_k127_1312343_0 1379698.RBG1_1C00001G1779 3.232e-120 390.0 COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria 2|Bacteria S ATPase associated with various cellular moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SRR21617311_k127_1316503_5 1217714.F975_00103 1.147e-09 59.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,3NMZY@468|Moraxellaceae 1236|Gammaproteobacteria I Beta-ketoacyl synthase, N-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_1316503_3 1382304.JNIL01000001_gene2953 2.526e-63 226.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,279HF@186823|Alicyclobacillaceae 91061|Bacilli I Enoyl-CoA hydratase/isomerase paaG - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 SRR21617311_k127_1316503_1 1379698.RBG1_1C00001G1630 9.653e-83 287.0 COG1230@1|root,COG1230@2|Bacteria,2NPHK@2323|unclassified Bacteria 2|Bacteria P Cation efflux family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer SRR21617311_k127_1316503_2 273057.SSO1312 2.579e-69 244.0 COG3396@1|root,arCOG04786@2157|Archaea 2157|Archaea S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC SRR21617311_k127_1316503_4 671065.MetMK1DRAFT_00016440 1.911e-52 193.0 COG3396@1|root,arCOG04786@2157|Archaea 2157|Archaea S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC SRR21617311_k127_1316503_0 1121405.dsmv_2388 7.008e-92 308.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales 28221|Deltaproteobacteria I PFAM Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SRR21617311_k127_1316931_1 760568.Desku_1902 7.211e-167 533.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae 186801|Clostridia G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB - 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme SRR21617311_k127_1316931_4 555088.DealDRAFT_0904 4.411e-38 147.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,42K0G@68298|Syntrophomonadaceae 186801|Clostridia F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 SRR21617311_k127_1316931_3 742742.HMPREF9452_01216 3.583e-39 156.0 COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4CVPK@84998|Coriobacteriia 84998|Coriobacteriia F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC SRR21617311_k127_1316931_5 1379698.RBG1_1C00001G0591 4.619e-24 119.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,Cadherin_3,DUF11,FlgD_ig SRR21617311_k127_1316931_0 1379698.RBG1_1C00001G0807 3.28e-206 671.0 COG2706@1|root,COG2706@2|Bacteria,2NR81@2323|unclassified Bacteria 2|Bacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - Big_5,VCBS SRR21617311_k127_1316931_2 1193181.BN10_50002 2.513e-81 301.0 COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria 201174|Actinobacteria M PFAM peptidase M6, immune inhibitor A - - - - - - - - - - - - Peptidase_M6 SRR21617311_k127_1325098_1 1123320.KB889680_gene2700 4.606e-78 277.0 COG0436@1|root,COG0436@2|Bacteria,2IB05@201174|Actinobacteria 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_1325098_0 1379698.RBG1_1C00001G0618 7.797e-255 801.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 SRR21617311_k127_1325098_4 1267534.KB906756_gene106 1.178e-21 109.0 COG1357@1|root,COG1357@2|Bacteria 2|Bacteria S protein homooligomerization - - - - - - - - - - - - Pentapeptide,Pentapeptide_3,Pentapeptide_4 SRR21617311_k127_1325098_3 1379698.RBG1_1C00001G1885 1.18e-30 128.0 COG1267@1|root,COG1267@2|Bacteria 2|Bacteria I phosphatidylglycerophosphatase activity pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA SRR21617311_k127_1325098_2 1379698.RBG1_1C00001G1884 3.109e-39 149.0 COG0558@1|root,COG0558@2|Bacteria,2NPJ9@2323|unclassified Bacteria 2|Bacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf SRR21617311_k127_1330833_3 1379698.RBG1_1C00001G1668 2.48e-110 374.0 COG0577@1|root,COG0577@2|Bacteria,2NQJU@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_1330833_1 1379698.RBG1_1C00001G1667 1.567e-184 583.0 COG0577@1|root,COG0577@2|Bacteria,2NQPT@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_1330833_2 1379698.RBG1_1C00001G1666 6.003e-121 391.0 COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria 2|Bacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_1330833_0 1379698.RBG1_1C00001G1665 7.352e-187 591.0 COG0845@1|root,COG0845@2|Bacteria,2NQ2U@2323|unclassified Bacteria 2|Bacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion acrA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SRR21617311_k127_1351685_7 1121890.AUDO01000010_gene315 1.685e-28 120.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2NSEK@237|Flavobacterium 976|Bacteroidetes C Dehydrogenase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 SRR21617311_k127_1351685_3 401053.AciPR4_1523 3.024e-94 323.0 COG0577@1|root,COG0577@2|Bacteria,3Y2IG@57723|Acidobacteria,2JHUY@204432|Acidobacteriia 204432|Acidobacteriia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_1351685_4 1047013.AQSP01000061_gene1217 3.826e-75 266.0 COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria 2|Bacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_D23 SRR21617311_k127_1351685_0 1379698.RBG1_1C00001G1217 1.738e-236 753.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria 2|Bacteria H Methylenetetrahydrofolate reductase yitJ - 1.5.1.20,2.1.1.10,2.1.1.13 ko:K00297,ko:K00547,ko:K00548 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523 M00017,M00377 R00650,R00946,R01224,R07168,R09365 RC00003,RC00035,RC00081,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0504 MTHFR,S-methyl_trans SRR21617311_k127_1351685_1 1379698.RBG1_1C00001G1066 4.201e-181 580.0 COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria 2|Bacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N SRR21617311_k127_1351685_5 264732.Moth_0431 4.591e-48 182.0 COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,24A0M@186801|Clostridia,42FFW@68295|Thermoanaerobacterales 186801|Clostridia S sugar fermentation stimulation protein sfsA - - ko:K06206 - - - - ko00000 - - - SfsA SRR21617311_k127_1351685_6 330214.NIDE3890 1.227e-32 134.0 COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae 40117|Nitrospirae C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske SRR21617311_k127_1351685_2 330214.NIDE3889 4.9e-108 365.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae 2|Bacteria C Cytochrome b/b6/petB qcrC - - ko:K00412,ko:K03888 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3 SRR21617311_k127_135220_2 1379698.RBG1_1C00001G0147 1.084e-13 72.0 COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C SRR21617311_k127_135220_0 1379698.RBG1_1C00001G0146 1.601e-87 297.0 COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria 2|Bacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A SRR21617311_k127_135220_1 1379698.RBG1_1C00001G0145 6.899e-21 98.0 2EPKR@1|root,33H7C@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_135220_3 1379698.RBG1_1C00001G0144 9.728e-05 45.0 2EQQP@1|root,33IAK@2|Bacteria 2|Bacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 SRR21617311_k127_1352422_2 511051.CSE_09680 1.696e-06 50.0 COG2403@1|root,COG2403@2|Bacteria 2|Bacteria S cyclic 2,3-diphosphoglycerate synthetase activity cpgS - - ko:K05716 - - R03298 RC00900 ko00000,ko01000 - - - cobW SRR21617311_k127_1352422_1 1444309.JAQG01000004_gene3592 2.013e-16 85.0 COG2318@1|root,COG2318@2|Bacteria,1VW3T@1239|Firmicutes,4HWQI@91061|Bacilli,26Y17@186822|Paenibacillaceae 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 SRR21617311_k127_1352422_0 1379698.RBG1_1C00001G0473 4.57e-141 453.0 COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria 2|Bacteria E Amino acid kinase family arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452 AA_kinase SRR21617311_k127_1360839_1 1379698.RBG1_1C00001G0338 2.014e-53 193.0 COG0046@1|root,COG0046@2|Bacteria,2NNPS@2323|unclassified Bacteria 2|Bacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SRR21617311_k127_1360839_3 546414.Deide_15510 8.817e-10 66.0 COG3794@1|root,COG3794@2|Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase_3,Cupredoxin_1 SRR21617311_k127_1360839_2 1379698.RBG1_1C00001G0819 3.074e-31 126.0 COG4911@1|root,COG4911@2|Bacteria,2NQ4H@2323|unclassified Bacteria 2|Bacteria S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 SRR21617311_k127_1360839_0 1379698.RBG1_1C00001G0334 2.703e-200 631.0 COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria 2|Bacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_0688 Urocanase,Urocanase_C,Urocanase_N SRR21617311_k127_1364223_0 485916.Dtox_2855 2.481e-56 202.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,261N7@186807|Peptococcaceae 186801|Clostridia M Polysaccharide biosynthesis protein - - 5.1.3.2,5.1.3.20,5.1.3.7 ko:K01784,ko:K02473,ko:K03274 ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100 M00064,M00361,M00362,M00632 R00291,R00418,R02984,R05176 RC00289,RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase,GDP_Man_Dehyd SRR21617311_k127_1364223_1 118166.JH976537_gene9 7.606e-41 165.0 COG0438@1|root,COG0438@2|Bacteria,1G0HB@1117|Cyanobacteria,1H7DC@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 SRR21617311_k127_1366520_0 1209989.TepiRe1_2353 1.155e-222 709.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales 186801|Clostridia J TIGRFAM Translation elongation factor fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR21617311_k127_1366520_1 1379698.RBG1_1C00001G0963 4.144e-118 387.0 COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria 2|Bacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SRR21617311_k127_1366520_2 1379698.RBG1_1C00001G0964 2.101e-24 104.0 COG2050@1|root,COG2050@2|Bacteria,2NQ0Q@2323|unclassified Bacteria 2|Bacteria Q Thioesterase superfamily - - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - 4HBT SRR21617311_k127_1373156_3 1313421.JHBV01000014_gene3897 2.614e-22 109.0 28JUF@1|root,2Z9JH@2|Bacteria,4NHS3@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - RskA SRR21617311_k127_1373156_1 1379698.RBG1_1C00001G1385 1.92e-110 370.0 COG3391@1|root,COG3391@2|Bacteria,2NQ7V@2323|unclassified Bacteria 2|Bacteria S Lactonase, 7-bladed beta-propeller - - - ko:K07004 - - - - ko00000 - - - Cytochrom_D1,Exo_endo_phos,He_PIG,LTD,Lactonase SRR21617311_k127_1373156_0 1379698.RBG1_1C00001G1384 4.648e-135 457.0 COG4206@1|root,COG4206@2|Bacteria,2NPT3@2323|unclassified Bacteria 2|Bacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec SRR21617311_k127_1373156_4 713586.KB900536_gene1112 1.298e-19 96.0 COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria,1X10E@135613|Chromatiales 135613|Chromatiales S Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH SRR21617311_k127_1373156_2 880073.Calab_0921 5.588e-28 116.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 SRR21617311_k127_137543_4 880073.Calab_2073 1.039e-57 225.0 2E09V@1|root,32VXB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_137543_3 1191523.MROS_0284 2.321e-63 231.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - PorP_SprF SRR21617311_k127_137543_7 665956.HMPREF1032_03141 6.648e-26 109.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae 186801|Clostridia J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 SRR21617311_k127_137543_1 1379698.RBG1_1C00001G0691 1.694e-100 336.0 COG3872@1|root,COG3872@2|Bacteria,2NP59@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF1385) prmC - - ko:K09153 - - - - ko00000 - - - DUF1385 SRR21617311_k127_137543_0 1379698.RBG1_1C00001G0692 5.595e-143 463.0 COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR21617311_k127_137543_6 1166016.W5S_3770 1.927e-39 155.0 COG0744@1|root,COG0744@2|Bacteria,1NXZS@1224|Proteobacteria,1SQRI@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Transglycosylase - - - - - - - - - - - - Transgly SRR21617311_k127_137543_5 1150621.SMUL_1371 1.043e-45 174.0 2E6D1@1|root,3310P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_137543_2 304371.MCP_0995 3.952e-78 275.0 COG0265@1|root,arCOG02833@2157|Archaea,2XT7Y@28890|Euryarchaeota,2NAWS@224756|Methanomicrobia 224756|Methanomicrobia O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 SRR21617311_k127_1386277_0 1499967.BAYZ01000171_gene5617 5.256e-80 275.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 SRR21617311_k127_1386277_2 1197477.IA57_03185 1.142e-25 121.0 COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,1I1H5@117743|Flavobacteriia 976|Bacteroidetes S Putative esterase - - - - - - - - - - - - Esterase SRR21617311_k127_1386277_1 1379698.RBG1_1C00001G0660 8.694e-78 280.0 COG2067@1|root,COG2067@2|Bacteria,2NPN1@2323|unclassified Bacteria 2|Bacteria I Membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X SRR21617311_k127_1388931_0 1379698.RBG1_1C00001G1309 1.448e-123 406.0 COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria 2|Bacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 SRR21617311_k127_1396976_0 656024.FsymDg_3327 9.981e-57 205.0 COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4ES2K@85013|Frankiales 201174|Actinobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2540c Chorismate_synt SRR21617311_k127_1396976_1 1379698.RBG1_1C00001G0159 6.352e-36 140.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1398989_1 266834.SM_b20933 1.575e-11 70.0 COG2202@1|root,COG2203@1|root,COG3290@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3920@2|Bacteria,1QQZ6@1224|Proteobacteria,2U3V1@28211|Alphaproteobacteria,4BFN9@82115|Rhizobiaceae 28211|Alphaproteobacteria T HWE histidine kinase exsG - - - - - - - - - - - GAF_2,HWE_HK,PAS_3,PAS_4,PAS_9 SRR21617311_k127_1398989_0 1242864.D187_009202 1.994e-86 303.0 COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9 SRR21617311_k127_1404389_0 1379698.RBG1_1C00001G0497 3.03e-51 193.0 COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family tolQ - - ko:K03561,ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - MotA_ExbB SRR21617311_k127_140482_1 326427.Cagg_0564 1.201e-18 94.0 COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia 32061|Chloroflexia S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SRR21617311_k127_1407638_0 443143.GM18_0717 0.0008502 50.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SRR21617311_k127_1416452_4 910964.GEAM_3259 1.991e-10 72.0 arCOG14100@1|root,2Z924@2|Bacteria,1R60F@1224|Proteobacteria,1S1CB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SIR2-like domain - - - - - - - - - - - - SIR2_2 SRR21617311_k127_1416452_0 1379698.RBG1_1C00001G0505 2.476e-284 910.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SRR21617311_k127_1416452_2 1125863.JAFN01000001_gene600 1.026e-92 311.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM ABC transporter related - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran SRR21617311_k127_1416452_3 889378.Spiaf_0715 4.655e-56 203.0 COG0765@1|root,COG0765@2|Bacteria,2J5BG@203691|Spirochaetes 203691|Spirochaetes P TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 SRR21617311_k127_1416452_1 1379698.RBG1_1C00001G0606 2.907e-239 753.0 COG0173@1|root,COG0173@2|Bacteria,2NNP3@2323|unclassified Bacteria 2|Bacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN678.aspS,iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon SRR21617311_k127_1417627_2 518766.Rmar_1232 5.769e-06 48.0 COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,4NS7V@976|Bacteroidetes 976|Bacteroidetes L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 SRR21617311_k127_1417627_0 671143.DAMO_2812 5.57e-212 667.0 COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria 2|Bacteria C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt SRR21617311_k127_1417627_1 1123288.SOV_2c08500 1.016e-56 207.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H2ME@909932|Negativicutes 909932|Negativicutes C PFAM FAD linked oxidase domain protein - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 SRR21617311_k127_1421771_4 1157490.EL26_00450 2.815e-30 125.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HJRJ@91061|Bacilli,27A5E@186823|Alicyclobacillaceae 91061|Bacilli L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - - - - - - - - - - DNA_binding_1 SRR21617311_k127_1421771_3 1196323.ALKF01000195_gene1957 6.566e-56 207.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,26S4B@186822|Paenibacillaceae 91061|Bacilli L 8-oxoguanine DNA glycosylase - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD SRR21617311_k127_1421771_1 1304880.JAGB01000003_gene1132 1.989e-115 380.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia 186801|Clostridia O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SRR21617311_k127_1421771_7 485915.Dret_1724 3.482e-07 61.0 COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM YbbR family protein - - - - - - - - - - - - YbbR SRR21617311_k127_1421771_0 1382356.JQMP01000003_gene2007 1.729e-119 395.0 COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi,27XY7@189775|Thermomicrobia 189775|Thermomicrobia P TOBE domain - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 SRR21617311_k127_1421771_6 696747.NIES39_K02130 6.107e-14 85.0 COG0457@1|root,COG0457@2|Bacteria,1G4DA@1117|Cyanobacteria,1HI8X@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_1421771_5 1384054.N790_14660 4.24e-24 112.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1X3SQ@135614|Xanthomonadales 135614|Xanthomonadales C FAD FMN-containing dehydrogenases dld - 1.1.2.4,1.1.5.12 ko:K00102,ko:K03777 ko00620,ko01120,map00620,map01120 - R00197,R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 SRR21617311_k127_1421771_2 243231.GSU0030 9.742e-65 230.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SZJ@69541|Desulfuromonadales 28221|Deltaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM SRR21617311_k127_142730_1 1379698.RBG1_1C00001G1362 1.666e-13 79.0 2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria 2|Bacteria S Yip1 domain - - - - - - - - - - - - Yip1 SRR21617311_k127_142730_0 1379698.RBG1_1C00001G1359 2.71e-205 645.0 COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria 2|Bacteria C pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase SRR21617311_k127_1428220_1 945713.IALB_0362 1.6e-109 376.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter msbA - - ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran SRR21617311_k127_1428220_3 1379698.RBG1_1C00001G1032 2.119e-55 208.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_1428220_2 1379698.RBG1_1C00001G1030 1.098e-64 227.0 COG1994@1|root,COG1994@2|Bacteria,2NPQP@2323|unclassified Bacteria 2|Bacteria S Peptidase family M50 ywhC - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50 SRR21617311_k127_1428220_0 1379698.RBG1_1C00001G1029 1.271e-189 604.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N SRR21617311_k127_1428220_4 945713.IALB_0617 8.541e-54 198.0 COG2094@1|root,COG2094@2|Bacteria 2|Bacteria L Belongs to the DNA glycosylase MPG family mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco SRR21617311_k127_1430996_9 1379698.RBG1_1C00001G0308 3.562e-26 111.0 COG1207@1|root,COG1207@2|Bacteria,2NNPC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 - iJN678.glmU,iLJ478.TM1629 Hexapep,NTP_transf_3,NTP_transferase SRR21617311_k127_1430996_5 1379698.RBG1_1C00001G0306 6.109e-46 168.0 COG0853@1|root,COG0853@2|Bacteria,2NPRF@2323|unclassified Bacteria 2|Bacteria H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox SRR21617311_k127_1430996_1 1379698.RBG1_1C00001G0305 3.197e-103 343.0 COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 ko:K01918,ko:K13799 ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110 M00052,M00119 R00158,R00512,R01665,R02473 RC00002,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin,Pantoate_ligase SRR21617311_k127_1430996_0 1379698.RBG1_1C00001G0304 3.01e-117 383.0 COG0413@1|root,COG0413@2|Bacteria,2NP1G@2323|unclassified Bacteria 2|Bacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf SRR21617311_k127_1430996_6 204669.Acid345_0083 4.081e-45 172.0 COG0801@1|root,COG0801@2|Bacteria,3Y57F@57723|Acidobacteria,2JJMS@204432|Acidobacteriia 204432|Acidobacteriia H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK SRR21617311_k127_1430996_4 1379698.RBG1_1C00001G0302 4.86e-48 174.0 COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria 2|Bacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB SRR21617311_k127_1430996_2 1123376.AUIU01000013_gene1914 3.701e-74 265.0 COG0436@1|root,COG0436@2|Bacteria,3J0G2@40117|Nitrospirae 40117|Nitrospirae E Aminotransferase class I and II - - 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_1430996_3 1121468.AUBR01000005_gene11 9.616e-58 207.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,42FJS@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran SRR21617311_k127_1430996_7 204669.Acid345_4518 1.292e-31 128.0 COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia 204432|Acidobacteriia I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS SRR21617311_k127_1431324_1 1009370.ALO_16362 7.442e-45 176.0 COG0614@1|root,COG1807@1|root,COG0614@2|Bacteria,COG1807@2|Bacteria,1U208@1239|Firmicutes,4H5XY@909932|Negativicutes 909932|Negativicutes M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SRR21617311_k127_1431324_2 1379698.RBG1_1C00001G1063 1.337e-34 137.0 COG0735@1|root,COG0735@2|Bacteria,2NQ8Z@2323|unclassified Bacteria 2|Bacteria P Belongs to the Fur family fur - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR SRR21617311_k127_1431324_0 237368.SCABRO_01997 2.36e-132 437.0 COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes 203682|Planctomycetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M SRR21617311_k127_1431324_3 1379698.RBG1_1C00001G1061 3.267e-07 55.0 COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria 2|Bacteria C NADH-quinone oxidoreductase, chain M nuoM-1 - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M SRR21617311_k127_1433117_1 1304888.ATWF01000001_gene758 0.0001564 51.0 2EJQV@1|root,30UHP@2|Bacteria,2GG2Z@200930|Deferribacteres 200930|Deferribacteres - - - - - - - - - - - - - - - SRR21617311_k127_1433117_0 1379698.RBG1_1C00001G1417 3.183e-20 93.0 COG1204@1|root,COG1204@2|Bacteria,2NS5J@2323|unclassified Bacteria 2|Bacteria L helicase superfamily c-terminal domain - - - ko:K03726 - - - - ko00000,ko01000 - - - DEAD,Helicase_C,Peptidase_C14 SRR21617311_k127_1435994_0 1379698.RBG1_1C00001G0402 1.676e-120 394.0 COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria 2|Bacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge SRR21617311_k127_1435994_1 292459.STH2612 2.909e-99 342.0 COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,24DV3@186801|Clostridia 186801|Clostridia T Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF4173 SRR21617311_k127_1435994_3 1380356.JNIK01000006_gene1530 1.36e-62 239.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales 201174|Actinobacteria KLT Serine threonine protein kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase SRR21617311_k127_1435994_5 593117.TGAM_0799 4.366e-09 68.0 COG0515@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci 183968|Thermococci KLT Serine threonine protein kinase - - - - - - - - - - - - PEGA,Pkinase SRR21617311_k127_1435994_4 1089550.ATTH01000001_gene1531 4.578e-51 208.0 COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes 976|Bacteroidetes U Parallel beta-helix repeats - - - - - - - - - - - - CHU_C,LTD SRR21617311_k127_1435994_2 1379698.RBG1_1C00001G0926 8.35e-80 273.0 COG1028@1|root,COG1028@2|Bacteria,2NPQY@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_1450334_5 1379698.RBG1_1C00001G0231 2.759e-08 59.0 COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria 2|Bacteria C HEAT repeats CP_0755 - - - - - - - - - - - HEAT_2,HEAT_PBS,Response_reg SRR21617311_k127_1450334_3 420324.KI912071_gene8168 5.067e-60 216.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - Rhodanese SRR21617311_k127_1450334_2 204669.Acid345_3766 3.22e-109 369.0 COG0312@1|root,COG0312@2|Bacteria,3Y7SM@57723|Acidobacteria 57723|Acidobacteria L Putative modulator of DNA gyrase - - - - - - - - - - - - PmbA_TldD SRR21617311_k127_1450334_0 204669.Acid345_3767 1.573e-186 594.0 COG0312@1|root,COG0312@2|Bacteria,3Y6TF@57723|Acidobacteria 57723|Acidobacteria L Putative modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SRR21617311_k127_1450334_1 1379698.RBG1_1C00001G0516 3.579e-174 554.0 COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria 2|Bacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SRR21617311_k127_1450334_4 153721.MYP_344 7.655e-09 64.0 2E06J@1|root,32VUI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1455490_0 1379698.RBG1_1C00001G0618 1.18e-83 286.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 SRR21617311_k127_14631_1 459349.CLOAM0099 4.471e-55 214.0 COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria 2|Bacteria S Peptidase family M28 - - 3.4.11.10 ko:K05994 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M28 SRR21617311_k127_14631_2 379066.GAU_1519 7.594e-07 58.0 COG0268@1|root,COG0268@2|Bacteria,1ZU6B@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p SRR21617311_k127_14631_0 1379698.RBG1_1C00001G1752 1.071e-111 368.0 COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria 2|Bacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SRR21617311_k127_1466531_1 498761.HM1_1926 9.613e-42 164.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia 186801|Clostridia E prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - ACT,PDH SRR21617311_k127_1466531_2 635013.TherJR_1608 2.561e-38 147.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,262D3@186807|Peptococcaceae 186801|Clostridia E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH - 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 SRR21617311_k127_1466531_0 1379698.RBG1_1C00001G1650 1.063e-83 285.0 COG0031@1|root,COG0031@2|Bacteria,2NNTU@2323|unclassified Bacteria 2|Bacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR21617311_k127_1475487_1 373903.Hore_02460 1.05e-46 173.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WAPJ@53433|Halanaerobiales 186801|Clostridia J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 SRR21617311_k127_1475487_2 1379698.RBG1_1C00001G1016 2.067e-38 147.0 COG0103@1|root,COG0103@2|Bacteria,2NPN8@2323|unclassified Bacteria 2|Bacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 SRR21617311_k127_1475487_0 1379698.RBG1_1C00001G1017 2.706e-93 312.0 COG0052@1|root,COG0052@2|Bacteria,2NP4M@2323|unclassified Bacteria 2|Bacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 SRR21617311_k127_1480599_0 1379698.RBG1_1C00001G1552 3.373e-69 264.0 COG1657@1|root,COG2931@1|root,COG4625@1|root,COG1657@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - 3.1.3.1,3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01077,ko:K01119,ko:K11751,ko:K20276 ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,ko02024,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020,map02024 M00126 R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02135,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R04620,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Cadherin-like,DUF4430,Flg_new,He_PIG,SLH SRR21617311_k127_1480599_1 1449050.JNLE01000003_gene2230 1.942e-08 68.0 COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1UY76@1239|Firmicutes,25G76@186801|Clostridia,36PFI@31979|Clostridiaceae 186801|Clostridia P Right handed beta helix region - - - - - - - - - - - - Beta_helix SRR21617311_k127_1483253_0 990285.RGCCGE502_20990 5.605e-41 154.0 COG2215@1|root,COG2215@2|Bacteria 2|Bacteria O Belongs to the NiCoT transporter (TC 2.A.52) family ureH - - ko:K07241 - - - - ko00000,ko02000 2.A.52.1 - - DsbD_2,NicO SRR21617311_k127_1483253_2 1267535.KB906767_gene836 1.217e-06 61.0 COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria,2JM3M@204432|Acidobacteriia 204432|Acidobacteriia C Protein of unknown function (DUF1553) - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 SRR21617311_k127_1483253_1 365044.Pnap_4548 4.937e-37 157.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2WEY0@28216|Betaproteobacteria,4AJBU@80864|Comamonadaceae 28216|Betaproteobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - - - - - - - - - - Cytochrom_D1,Lactonase SRR21617311_k127_1498895_0 648996.Theam_0155 1.975e-116 386.0 COG1060@1|root,COG1060@2|Bacteria,2G3U8@200783|Aquificae 200783|Aquificae H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnC - 1.21.98.1 ko:K11784 ko00130,ko01110,map00130,map01110 - R08588 RC02329 ko00000,ko00001,ko01000 - - - Radical_SAM SRR21617311_k127_1498895_1 1121456.ATVA01000011_gene1645 1.438e-16 86.0 COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,2M954@213115|Desulfovibrionales 28221|Deltaproteobacteria S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth SRR21617311_k127_1500057_2 204669.Acid345_2787 2.507e-76 263.0 COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia 204432|Acidobacteriia Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SRR21617311_k127_1500057_0 1379698.RBG1_1C00001G0615 2.093e-225 713.0 COG4805@1|root,COG4805@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 SRR21617311_k127_1500057_1 1379698.RBG1_1C00001G1631 3.992e-131 426.0 COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 SRR21617311_k127_1507587_7 32057.KB217480_gene7997 8.612e-72 251.0 COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales 1117|Cyanobacteria KLT PFAM KWG Leptospira - - - - - - - - - - - - SLH,WG_beta_rep SRR21617311_k127_1507587_11 1229172.JQFA01000002_gene4513 3.791e-12 76.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1G1B2@1117|Cyanobacteria,1H78W@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Peptidase family M23 - - 3.4.24.75 ko:K08259 - - - - ko00000,ko01000,ko01002,ko01011 - - - LysM,Peptidase_M23 SRR21617311_k127_1507587_8 469371.Tbis_3588 6.763e-68 244.0 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4DXY2@85010|Pseudonocardiales 201174|Actinobacteria K Belongs to the ParB family parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SRR21617311_k127_1507587_3 880073.Calab_0243 5.04e-105 347.0 COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria 2|Bacteria D Cobyrinic acid ac-diamide synthase soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SRR21617311_k127_1507587_10 1122947.FR7_4256 2.603e-21 102.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes 909932|Negativicutes J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB SRR21617311_k127_1507587_1 330214.NIDE0362 3.215e-211 675.0 COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae 40117|Nitrospirae D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc SRR21617311_k127_1507587_4 1089548.KI783301_gene2570 7.052e-100 336.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3WFC7@539002|Bacillales incertae sedis 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase trxB5 - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2 SRR21617311_k127_1507587_5 1173028.ANKO01000170_gene3367 4.24e-99 331.0 COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin SRR21617311_k127_1507587_0 1041930.Mtc_2416 2.044e-249 790.0 COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia 224756|Methanomicrobia P ATPase, P-type (transporting), HAD superfamily, subfamily IC copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase SRR21617311_k127_1507587_6 234267.Acid_1248 8.558e-87 295.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria 57723|Acidobacteria P SNARE associated Golgi protein - - - - - - - - - - - - Rhodanese,SNARE_assoc SRR21617311_k127_1507587_12 1267535.KB906767_gene561 5.594e-11 63.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia 204432|Acidobacteriia P SNARE associated Golgi protein - - - - - - - - - - - - Rhodanese,SNARE_assoc SRR21617311_k127_1507587_9 1191523.MROS_0725 1.04e-39 158.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC SRR21617311_k127_1507587_2 1379698.RBG1_1C00001G0178 2.669e-137 450.0 COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria 2|Bacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr SRR21617311_k127_1509271_2 1499967.BAYZ01000008_gene5426 8.014e-40 151.0 COG0324@1|root,COG0324@2|Bacteria,2NP6D@2323|unclassified Bacteria 2|Bacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT SRR21617311_k127_1509271_0 1379698.RBG1_1C00001G1139 1.734e-162 533.0 COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria 2|Bacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C SRR21617311_k127_1509271_1 1379698.RBG1_1C00001G1474 2.914e-62 220.0 COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria 2|Bacteria I Cobalamin B12-binding - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding SRR21617311_k127_1509271_3 639030.JHVA01000001_gene2899 1.814e-19 92.0 COG1943@1|root,COG1943@2|Bacteria,3Y4PK@57723|Acidobacteria,2JJBM@204432|Acidobacteriia 204432|Acidobacteriia L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp SRR21617311_k127_151138_2 1123393.KB891316_gene1452 6.556e-12 77.0 2C76Q@1|root,30D3Y@2|Bacteria,1RF8T@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_151138_1 1379698.RBG1_1C00001G1112 1.629e-18 89.0 COG1551@1|root,COG1551@2|Bacteria,2NQ31@2323|unclassified Bacteria 2|Bacteria J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563,ko:K13626 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko02035,ko03019 - - - CsrA SRR21617311_k127_151138_0 485916.Dtox_0670 2.112e-23 108.0 COG1699@1|root,COG1699@2|Bacteria,1U46U@1239|Firmicutes,259AI@186801|Clostridia,263CI@186807|Peptococcaceae 186801|Clostridia N Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum fliW - - ko:K13626 - - - - ko00000,ko02035 - - - FliW SRR21617311_k127_1513148_0 105559.Nwat_0994 3.342e-26 121.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S479@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - FG-GAP SRR21617311_k127_1513148_1 517418.Ctha_2367 4.778e-08 64.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - STT3 SRR21617311_k127_1516655_2 443143.GM18_3077 5.805e-34 134.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,43TTF@69541|Desulfuromonadales 28221|Deltaproteobacteria IQ KR domain fabG-2 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_1516655_0 1379698.RBG1_1C00001G1827 4.831e-100 335.0 COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria 2|Bacteria I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 SRR21617311_k127_1516655_1 1379698.RBG1_1C00001G1828 5.469e-61 214.0 COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria 2|Bacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SRR21617311_k127_1523089_0 1379698.RBG1_1C00001G0933 9.045e-129 447.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02584,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - FHA,GAF,GAF_2,HTH_8,Sigma54_activat SRR21617311_k127_1523089_1 1379698.RBG1_1C00001G0343 1.066e-48 190.0 COG0286@1|root,COG0286@2|Bacteria 2|Bacteria V site-specific DNA-methyltransferase (adenine-specific) activity - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase SRR21617311_k127_1530383_0 1392489.JPOL01000002_gene2530 1.879e-97 348.0 COG1404@1|root,COG2374@1|root,COG3291@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NGJJ@976|Bacteroidetes,1I3TI@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the peptidase S8 family - - - - - - - - - - - - - SRR21617311_k127_1532949_0 1379698.RBG1_1C00001G1886 1.086e-136 447.0 COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria 2|Bacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth SRR21617311_k127_1535809_0 1379698.RBG1_1C00001G1097 9.81e-118 392.0 COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria 2|Bacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM SRR21617311_k127_1535809_1 234267.Acid_3653 4.346e-05 49.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,Lipase_2 SRR21617311_k127_1536741_1 1379698.RBG1_1C00001G0686 1.169e-87 297.0 COG1252@1|root,COG1252@2|Bacteria,2NP3T@2323|unclassified Bacteria 2|Bacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase ndh GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU12290,iYO844.BSU32100 Pyr_redox_2 SRR21617311_k127_1536741_0 880073.Calab_0005 1.925e-224 716.0 COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria 2|Bacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS SRR21617311_k127_1536741_2 1379698.RBG1_1C00001G1038 3.989e-25 106.0 COG0859@1|root,COG0859@2|Bacteria,2NPXQ@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_1541065_0 1379698.RBG1_1C00001G0186 1.355e-313 973.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria 2|Bacteria G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.3.13,2.7.9.1 ko:K01006,ko:K22424 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N SRR21617311_k127_1541065_1 665571.STHERM_c10350 1.387e-19 93.0 COG0157@1|root,COG0157@2|Bacteria,2J93N@203691|Spirochaetes 203691|Spirochaetes H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767,ko:K03813 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N SRR21617311_k127_1546879_0 1379698.RBG1_1C00001G0460 0.0 1297.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon SRR21617311_k127_1546879_2 323259.Mhun_2196 1.925e-77 265.0 COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2NAKT@224756|Methanomicrobia 224756|Methanomicrobia E ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_1546879_1 1313304.CALK_1725 2.231e-94 323.0 COG4591@1|root,COG4591@2|Bacteria 2|Bacteria M lipoprotein localization to outer membrane - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_1575266_2 1379698.RBG1_1C00001G0504 3.494e-51 185.0 COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria 2|Bacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SRR21617311_k127_1575266_1 1379698.RBG1_1C00001G0503 4.625e-108 373.0 COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria 2|Bacteria M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723,PMT_2 SRR21617311_k127_1575266_3 1379698.RBG1_1C00001G0502 1.572e-44 173.0 COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria 2|Bacteria S Outer membrane lipoprotein cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri SRR21617311_k127_1575266_5 1379698.RBG1_1C00001G0501 3.521e-34 138.0 COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria 2|Bacteria M OmpA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA SRR21617311_k127_1575266_0 1379698.RBG1_1C00001G0500 7.974e-112 379.0 COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria 2|Bacteria U TolB amino-terminal domain tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N SRR21617311_k127_1575266_6 1379698.RBG1_1C00001G0499 1.456e-29 127.0 COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria 2|Bacteria M TonB C terminal - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - CarbopepD_reg_2,TonB_2,TonB_C SRR21617311_k127_1575266_4 1379698.RBG1_1C00001G0498 1.543e-34 136.0 COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria 2|Bacteria U Biopolymer transport protein ExbD/TolR tolR - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD SRR21617311_k127_1576954_1 1379698.RBG1_1C00001G1478 2.012e-77 263.0 COG1704@1|root,COG1704@2|Bacteria,2NPIW@2323|unclassified Bacteria 2|Bacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA SRR21617311_k127_1576954_2 1297570.MESS4_710051 7.89e-08 55.0 2DEJE@1|root,2ZN82@2|Bacteria,1PB33@1224|Proteobacteria,2UY1B@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_1576954_0 1379698.RBG1_1C00001G1477 4.687e-182 587.0 COG0608@1|root,COG0608@2|Bacteria,2NNRX@2323|unclassified Bacteria 2|Bacteria L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SRR21617311_k127_1585857_1 1379698.RBG1_1C00001G0287 5.272e-32 128.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 SRR21617311_k127_1585857_0 235985.BBPN01000033_gene6 2.044e-38 168.0 COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,2NM34@228398|Streptacidiphilus 201174|Actinobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF4352,Pkinase,TPR_10 SRR21617311_k127_1591962_1 1379698.RBG1_1C00001G0548 9.521e-39 151.0 COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria 2|Bacteria S Lipopolysaccharide-assembly, LptC-related lptC - - ko:K09774,ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC SRR21617311_k127_1591962_0 1379698.RBG1_1C00001G0545 5.175e-142 458.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2NNNB@2323|unclassified Bacteria 2|Bacteria M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 2.5.1.55,5.3.1.13 ko:K01627,ko:K03281,ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530,R03254 RC00435,RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 2.A.49 - iAF987.Gmet_1278 CBS,SIS SRR21617311_k127_1602860_1 344747.PM8797T_05200 8.742e-05 55.0 COG1506@1|root,COG1506@2|Bacteria,2IXV8@203682|Planctomycetes 203682|Planctomycetes E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 SRR21617311_k127_1602860_0 1122603.ATVI01000005_gene3605 6.449e-52 188.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X97T@135614|Xanthomonadales 135614|Xanthomonadales M Thrombospondin type 3 repeat - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 SRR21617311_k127_1604413_3 1051632.TPY_1164 2.243e-36 140.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3WCWI@538999|Clostridiales incertae sedis 186801|Clostridia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR21617311_k127_1604413_5 1122939.ATUD01000002_gene1445 7.944e-10 60.0 COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CQBZ@84995|Rubrobacteria 84995|Rubrobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI SRR21617311_k127_1604413_4 945713.IALB_2392 8.893e-35 141.0 COG0135@1|root,COG0135@2|Bacteria 2|Bacteria E phosphoribosylanthranilate isomerase activity trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI SRR21617311_k127_1604413_0 575540.Isop_3670 1.013e-71 251.0 COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes 203682|Planctomycetes E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS SRR21617311_k127_1604413_2 1235279.C772_02726 2.802e-59 222.0 COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,4HCUB@91061|Bacilli,26E16@186818|Planococcaceae 91061|Bacilli EGP MFS_1 like family - - - - - - - - - - - - MFS_1,MFS_1_like SRR21617311_k127_1604413_1 264732.Moth_1340 4.624e-71 246.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 SRR21617311_k127_1613499_2 706587.Desti_2948 1.024e-84 298.0 COG0069@1|root,COG0069@2|Bacteria 2|Bacteria E glutamate synthase activity - - - - - - - - - - - - Fer4,Glu_synthase SRR21617311_k127_1613499_1 880072.Desac_1036 7.863e-165 530.0 COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Glutamate synthase - - - - - - - - - - - - Fer4,Glu_synthase SRR21617311_k127_1613499_0 880072.Desac_1035 2.163e-177 567.0 COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria 28221|Deltaproteobacteria E GXGXG motif - - - - - - - - - - - - GATase_6,GXGXG SRR21617311_k127_1622760_1 1379698.RBG1_1C00001G0164 5.984e-71 249.0 COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria 2|Bacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind SRR21617311_k127_1622760_0 1379698.RBG1_1C00001G0166 9.024e-139 448.0 COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria 2|Bacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR21617311_k127_1622760_2 56780.SYN_00576 1.059e-38 146.0 COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales 28221|Deltaproteobacteria M WxcM-like, C-terminal - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom SRR21617311_k127_1630628_4 373903.Hore_05640 1.711e-38 148.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WAH1@53433|Halanaerobiales 186801|Clostridia J TIGRFAM phenylalanyl-tRNA synthetase, beta subunit pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind SRR21617311_k127_1630628_0 1379698.RBG1_1C00001G1119 1.621e-121 398.0 COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d SRR21617311_k127_1630628_3 1379698.RBG1_1C00001G1118 9.564e-45 164.0 COG0292@1|root,COG0292@2|Bacteria,2NPQQ@2323|unclassified Bacteria 2|Bacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 SRR21617311_k127_1630628_5 269799.Gmet_1413 1.147e-13 75.0 COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WWDG@28221|Deltaproteobacteria,43VD2@69541|Desulfuromonadales 28221|Deltaproteobacteria J structural constituent of ribosome rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p SRR21617311_k127_1630628_2 1379698.RBG1_1C00001G1116 2.184e-66 234.0 COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria 2|Bacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N SRR21617311_k127_1630628_1 1120971.AUCA01000035_gene2795 1.488e-72 249.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,2798N@186823|Alicyclobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD SRR21617311_k127_1631552_0 1379698.RBG1_1C00001G1056 4.646e-219 709.0 COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria 2|Bacteria C Molydopterin dinucleotide binding domain hcnA - 1.17.1.9,1.4.99.5,1.5.3.1 ko:K00123,ko:K00302,ko:K10814 ko00260,ko00460,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,map00260,map00460,map00630,map00680,map01100,map01110,map01120,map01200 - R00374,R00519,R00610,R05704 RC00060,RC00557,RC02796,RC02808 ko00000,ko00001,ko01000,ko02042 - - - Fer2_4 SRR21617311_k127_1631552_1 1379698.RBG1_1C00001G1057 1.131e-140 454.0 COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh SRR21617311_k127_1631552_2 1379698.RBG1_1C00001G1875 1.115e-76 260.0 COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 ko:K00337,ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iNJ661.Rv3153 Fer4 SRR21617311_k127_1631552_3 1379698.RBG1_1C00001G1058 1.092e-42 162.0 COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria 2|Bacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 SRR21617311_k127_1631552_4 1379698.RBG1_1C00001G1059 4.874e-39 148.0 COG0713@1|root,COG0713@2|Bacteria,2NPU2@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 SRR21617311_k127_1637656_2 1379698.RBG1_1C00001G1101 1.266e-23 112.0 COG1404@1|root,COG2911@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,2NP8X@2323|unclassified Bacteria 2|Bacteria O Subtilase family - - - - - - - - - - - - Cohesin,FlgD_ig,Inhibitor_I9,Peptidase_S74,Peptidase_S8 SRR21617311_k127_1637656_5 398512.JQKC01000001_gene2200 1.07e-05 54.0 COG5297@1|root,COG5297@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase family 6 - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Beta-lactamase,CBM60,CBM_2,Cellulase,DUF1593,PSCyt3,fn3 SRR21617311_k127_1637656_1 1284708.HMPREF1634_06545 5.646e-76 274.0 COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia 186801|Clostridia G abc transporter atp-binding protein ecfA - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran SRR21617311_k127_1637656_3 1347087.CBYO010000020_gene2860 8.335e-11 66.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_1637656_0 1459636.NTE_00013 1.182e-80 275.0 COG2085@1|root,arCOG00457@2157|Archaea 2157|Archaea S NADPH-dependent F420 reductase - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored,HTH_10 SRR21617311_k127_1641263_1 1379698.RBG1_1C00001G1156 6.136e-71 246.0 COG0618@1|root,COG0618@2|Bacteria,2NPK0@2323|unclassified Bacteria 2|Bacteria S DHH family nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 - R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 - - - DHH,DHHA1 SRR21617311_k127_1641263_3 443143.GM18_1166 5.24e-67 239.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales 28221|Deltaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N SRR21617311_k127_1641263_2 1379698.RBG1_1C00001G1158 1.768e-68 245.0 COG0196@1|root,COG0196@2|Bacteria,2NPCV@2323|unclassified Bacteria 2|Bacteria H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K07011,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase SRR21617311_k127_1641263_5 1121296.JONJ01000015_gene155 4.206e-26 109.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 186801|Clostridia J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 SRR21617311_k127_1641263_0 1379698.RBG1_1C00001G1160 8.706e-281 880.0 COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria 2|Bacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SRR21617311_k127_1641263_4 1379698.RBG1_1C00001G1161 5.694e-48 173.0 COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria 2|Bacteria S Belongs to the peptidase M16 family pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_1649657_0 1379698.RBG1_1C00001G0334 7.269e-98 322.0 COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria 2|Bacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_0688 Urocanase,Urocanase_C,Urocanase_N SRR21617311_k127_1649657_1 1379698.RBG1_1C00001G0333 1.41e-96 325.0 COG1228@1|root,COG1228@2|Bacteria,2NNTC@2323|unclassified Bacteria 2|Bacteria Q Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 SRR21617311_k127_165209_2 404589.Anae109_1195 1.897e-26 111.0 COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - AhpC-TSA SRR21617311_k127_165209_5 986075.CathTA2_1858 1.94e-09 61.0 COG1225@1|root,COG1225@2|Bacteria,1VGP9@1239|Firmicutes,4HQ3V@91061|Bacilli 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA SRR21617311_k127_165209_0 1379698.RBG1_1C00001G0821 1.611e-172 547.0 COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria 2|Bacteria P Sodium Bile acid symporter family arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 ko:K03325,ko:K03741 - - - - ko00000,ko01000,ko02000 2.A.59 - iYO844.BSU25790 SBF SRR21617311_k127_165209_1 1232410.KI421412_gene349 3.289e-60 217.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,43UU6@69541|Desulfuromonadales 28221|Deltaproteobacteria H Biotin/lipoate A/B protein ligase family lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,NUDIX SRR21617311_k127_165209_3 255470.cbdbA1252 3.764e-22 99.0 2A4E9@1|root,2ZJRI@2|Bacteria,2GAVU@200795|Chloroflexi,34DG2@301297|Dehalococcoidia 301297|Dehalococcoidia - - - - - - - - - - - - - - - SRR21617311_k127_165209_4 886377.Murru_0369 2.96e-14 78.0 COG0346@1|root,COG0346@2|Bacteria,4NX7N@976|Bacteroidetes 976|Bacteroidetes E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase SRR21617311_k127_165209_6 477974.Daud_0515 1.023e-08 56.0 COG1598@1|root,COG1598@2|Bacteria,1VHGY@1239|Firmicutes,24S40@186801|Clostridia,2663A@186807|Peptococcaceae 186801|Clostridia S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox SRR21617311_k127_165211_0 1379698.RBG1_1C00001G1242 3.72e-06 50.0 COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria 2|Bacteria S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22,MFS_1 SRR21617311_k127_165211_1 518766.Rmar_2110 0.0002845 49.0 COG5544@1|root,COG5544@2|Bacteria,4PEU9@976|Bacteroidetes,1FJMF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Lipoprotein - - - - - - - - - - - - - SRR21617311_k127_1657944_0 671143.DAMO_1167 3.232e-139 454.0 COG2982@1|root,COG2982@2|Bacteria 2|Bacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - DUF748 SRR21617311_k127_1658316_1 1379698.RBG1_1C00001G0843 2.72e-24 106.0 COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria 2|Bacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.1.3.5 ko:K07025,ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SRR21617311_k127_1658316_0 1379698.RBG1_1C00001G0842 2.119e-78 266.0 COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SRR21617311_k127_1662637_2 886293.Sinac_0625 6.729e-10 66.0 COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes 2|Bacteria S PFAM Peptidase M16 inactive domain pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_1662637_1 1379698.RBG1_1C00001G0327 5.445e-58 216.0 COG1664@1|root,COG1664@2|Bacteria 2|Bacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin SRR21617311_k127_1662637_0 1499967.BAYZ01000170_gene5483 3.57e-211 687.0 COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_166434_3 634497.HAH_2125 9.766e-15 79.0 COG0438@1|root,arCOG01410@2157|Archaea,2XV5R@28890|Euryarchaeota,23USK@183963|Halobacteria 183963|Halobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_166434_1 397278.JOJN01000001_gene2784 3.1e-89 310.0 COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DSH1@85009|Propionibacteriales 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_166434_2 42256.RradSPS_2706 7.911e-77 284.0 COG4671@1|root,COG4671@2|Bacteria,2IAST@201174|Actinobacteria 201174|Actinobacteria S Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C SRR21617311_k127_166434_0 667014.Thein_1210 9.46e-123 409.0 COG1004@1|root,COG1004@2|Bacteria,2GGQN@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR21617311_k127_1664569_0 1379698.RBG1_1C00001G1317 8.138e-44 176.0 COG1361@1|root,COG3391@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - - SRR21617311_k127_1664569_1 391625.PPSIR1_03608 3.052e-18 91.0 COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,2Z164@29|Myxococcales 28221|Deltaproteobacteria S Uncharacterised protein family (UPF0158) - - - - - - - - - - - - UPF0158 SRR21617311_k127_1664837_0 1379698.RBG1_1C00001G1659 3.004e-132 441.0 COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 SRR21617311_k127_1664837_3 1131269.AQVV01000046_gene2111 1.257e-29 121.0 COG0718@1|root,COG0718@2|Bacteria 2|Bacteria S YbaB/EbfC DNA-binding family ybaB - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd SRR21617311_k127_1664837_2 1379698.RBG1_1C00001G1657 6.177e-83 283.0 COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria 2|Bacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 SRR21617311_k127_1664837_4 1125863.JAFN01000001_gene3181 6.934e-27 110.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria 28221|Deltaproteobacteria K cold-shock protein cspD - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SRR21617311_k127_1664837_1 1379698.RBG1_1C00001G1656 1.396e-99 327.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW SRR21617311_k127_1668505_0 1379698.RBG1_1C00001G0195 3.129e-285 889.0 COG1048@1|root,COG1048@2|Bacteria,2NNWW@2323|unclassified Bacteria 2|Bacteria C Aconitase C-terminal domain dmdA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2763 Aconitase,Aconitase_C SRR21617311_k127_167169_2 1379698.RBG1_1C00001G1209 2.145e-19 94.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - DUF2723,PMT_2 SRR21617311_k127_167169_0 1379698.RBG1_1C00001G1210 3.192e-196 624.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family nla19 - - ko:K02667,ko:K07713,ko:K07714,ko:K19641 ko02020,map02020 M00499,M00500,M00501,M00772 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1688236_0 1379698.RBG1_1C00001G0635 1.535e-161 513.0 COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria 2|Bacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SRR21617311_k127_1702005_8 1379698.RBG1_1C00001G1567 1.13e-36 144.0 COG0203@1|root,COG0203@2|Bacteria,2NPYQ@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein L17 rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879,ko:K16193 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 SRR21617311_k127_1702005_1 1379698.RBG1_1C00001G1568 7.492e-122 399.0 COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SRR21617311_k127_1702005_3 1379698.RBG1_1C00001G1569 1.514e-76 267.0 COG0522@1|root,COG0522@2|Bacteria,2NPCC@2323|unclassified Bacteria 2|Bacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 SRR21617311_k127_1702005_5 1379698.RBG1_1C00001G1570 5.749e-56 198.0 COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria 2|Bacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 SRR21617311_k127_1702005_6 1379698.RBG1_1C00001G1571 1.496e-54 194.0 COG0099@1|root,COG0099@2|Bacteria,2NPKH@2323|unclassified Bacteria 2|Bacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 SRR21617311_k127_1702005_9 926550.CLDAP_03870 2.74e-12 68.0 COG0257@1|root,COG0257@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 SRR21617311_k127_1702005_7 1379698.RBG1_1C00001G1573 5.696e-40 148.0 COG0361@1|root,COG0361@2|Bacteria,2NPNU@2323|unclassified Bacteria 2|Bacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a SRR21617311_k127_1702005_2 1089553.Tph_c25640 2.296e-90 308.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,42F6V@68295|Thermoanaerobacterales 186801|Clostridia J TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SRR21617311_k127_1702005_4 1321782.HMPREF1986_00986 3.011e-60 215.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,2PQTX@265975|Oribacterium 186801|Clostridia F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iHN637.CLJU_RS20110 ADK,ADK_lid SRR21617311_k127_1702005_0 1379698.RBG1_1C00001G1576 9.292e-145 464.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SRR21617311_k127_1704395_2 398578.Daci_2521 3.617e-10 63.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VPNU@28216|Betaproteobacteria,4AFGQ@80864|Comamonadaceae 28216|Betaproteobacteria M TIGRFAM YD repeat protein - - - - - - - - - - - - Ntox16,RHS,RHS_repeat SRR21617311_k127_1704395_0 1379698.RBG1_1C00001G1274 1.166e-163 532.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family atoC - - ko:K07712,ko:K07713,ko:K07714,ko:K10943 ko02020,ko05111,map02020,map05111 M00497,M00499,M00500,M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1704395_1 1379698.RBG1_1C00001G1275 4.02e-42 162.0 COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria 2|Bacteria T Signal transduction histidine kinase, nitrogen specific, NtrB atoS - 2.7.13.3 ko:K07708,ko:K07710,ko:K10942 ko02020,ko05111,map02020,map05111 M00497,M00500,M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_8,PAS_9 SRR21617311_k127_1705456_3 858215.Thexy_0225 0.0003345 45.0 COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42GA1@68295|Thermoanaerobacterales 186801|Clostridia E HAD-superfamily hydrolase, subfamily IB, PSPase-like mtnX - - - - - - - - - - - HAD,Put_Phosphatase SRR21617311_k127_1705456_0 1519464.HY22_12340 3.356e-233 748.0 COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1FEI3@1090|Chlorobi 1090|Chlorobi GJM Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - 2.7.7.13,5.4.2.8 ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III SRR21617311_k127_1705456_2 1379698.RBG1_1C00001G1104 1.836e-38 153.0 2B0A3@1|root,31SM2@2|Bacteria,2NRWJ@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 SRR21617311_k127_1705456_1 215803.DB30_0369 2.675e-108 364.0 COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YTZR@29|Myxococcales 28221|Deltaproteobacteria EK Pyridoxal-phosphate dependent enzyme - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP SRR21617311_k127_1706468_0 1379698.RBG1_1C00001G0726 1.574e-136 447.0 COG1063@1|root,COG1063@2|Bacteria,2NPK3@2323|unclassified Bacteria 2|Bacteria E Zinc-binding dehydrogenase tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SRR21617311_k127_1706468_1 929703.KE386491_gene4159 6.228e-08 54.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia 976|Bacteroidetes H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_1708271_3 1379698.RBG1_1C00001G0185 0.0001913 53.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Cadherin,DUF285,GON,Reprolysin_5 SRR21617311_k127_1708271_1 748449.Halha_1884 1.617e-57 216.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales 186801|Clostridia S CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SRR21617311_k127_1708271_2 1379698.RBG1_1C00001G0610 5.374e-31 127.0 COG0319@1|root,COG0319@2|Bacteria,2NQ0W@2323|unclassified Bacteria 2|Bacteria S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 - - - UPF0054 SRR21617311_k127_1708271_0 1379698.RBG1_1C00001G0609 2.259e-114 373.0 COG1702@1|root,COG1702@2|Bacteria,2NNZF@2323|unclassified Bacteria 2|Bacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH SRR21617311_k127_1711537_13 1379698.RBG1_1C00001G0222 7.329e-41 154.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria 2|Bacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N SRR21617311_k127_1711537_2 1379698.RBG1_1C00001G0426 4.619e-187 593.0 2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1711537_18 247490.KSU1_D0989 5.708e-26 115.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - - - - - - - - - - EAL,GGDEF,HATPase_c,HTH_3,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg SRR21617311_k127_1711537_19 1379698.RBG1_1C00001G0683 5.823e-18 88.0 COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria 2|Bacteria P (Rieske (2Fe-2S) domain) - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske SRR21617311_k127_1711537_15 1267535.KB906767_gene424 3.66e-31 126.0 COG0494@1|root,COG0494@2|Bacteria,3Y55X@57723|Acidobacteria 57723|Acidobacteria L Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX SRR21617311_k127_1711537_9 1128421.JAGA01000002_gene614 3.906e-82 282.0 COG1194@1|root,COG1194@2|Bacteria,2NPAU@2323|unclassified Bacteria 2|Bacteria L endonuclease III mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 SRR21617311_k127_1711537_17 1379698.RBG1_1C00001G1559 8.639e-28 123.0 COG0671@1|root,COG0671@2|Bacteria,2NPZH@2323|unclassified Bacteria 2|Bacteria I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - DUF3703,PAP2 SRR21617311_k127_1711537_21 1121878.AUGL01000005_gene2608 1.204e-08 62.0 COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SBEZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase SRR21617311_k127_1711537_11 1379698.RBG1_1C00001G1086 8.152e-76 264.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase nueM - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 SRR21617311_k127_1711537_5 1379698.RBG1_1C00001G1096 4.559e-140 458.0 COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SRR21617311_k127_1711537_1 1379698.RBG1_1C00001G0645 3.62e-187 594.0 COG2031@1|root,COG2031@2|Bacteria 2|Bacteria I Short chain fatty acid transporter atoE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - iECUMN_1333.ECUMN_2561 SCFA_trans SRR21617311_k127_1711537_12 1379698.RBG1_1C00001G0649 2.759e-68 240.0 COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria 2|Bacteria H Belongs to the ComB family comB GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp SRR21617311_k127_1711537_4 1379698.RBG1_1C00001G0650 8.125e-158 507.0 COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C SRR21617311_k127_1711537_8 370438.PTH_0927 3.993e-91 312.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae 186801|Clostridia J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C SRR21617311_k127_1711537_0 748247.AZKH_2015 1.113e-213 672.0 COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C SRR21617311_k127_1711537_14 1121472.AQWN01000005_gene2505 2.788e-31 126.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,261QI@186807|Peptococcaceae 186801|Clostridia C FeS cluster assembly scaffold protein NifU nifU - - ko:K04488 - - - - ko00000 - - - NifU_N SRR21617311_k127_1711537_16 555088.DealDRAFT_1165 4.86e-29 126.0 COG0664@1|root,COG0664@2|Bacteria,1V8FC@1239|Firmicutes,25MZJ@186801|Clostridia,42KUQ@68298|Syntrophomonadaceae 186801|Clostridia K Cyclic nucleotide-monophosphate binding domain - - - ko:K09766 - - - - ko00000 - - - HTH_Crp_2,cNMP_binding SRR21617311_k127_1711537_3 1283299.AUKG01000002_gene3857 1.32e-162 529.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria 84995|Rubrobacteria C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2 SRR21617311_k127_1711537_10 176280.SE_0324 2.056e-79 272.0 COG1028@1|root,COG1028@2|Bacteria,1UU2F@1239|Firmicutes,4HCVI@91061|Bacilli,4GY0R@90964|Staphylococcaceae 91061|Bacilli IQ KR domain fabG5 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_1711537_6 1379698.RBG1_1C00001G1544 7.969e-131 429.0 COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria 2|Bacteria T Integral membrane sensor signal transduction histidine kinase vicK - 2.1.1.80,2.7.13.3,3.1.1.61 ko:K07709,ko:K13924 ko02020,ko02030,map02020,map02030 M00499,M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA SRR21617311_k127_1711537_7 1379698.RBG1_1C00001G1543 6.158e-99 325.0 COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SRR21617311_k127_171179_3 1379698.RBG1_1C00001G1299 5.078e-16 79.0 COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria 2|Bacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 SRR21617311_k127_171179_1 1379698.RBG1_1C00001G1300 2.635e-94 319.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c pbrT - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrom_C,Cytochrome_CBB3,FTR1 SRR21617311_k127_171179_0 1379698.RBG1_1C00001G1301 7.16e-159 510.0 COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria 2|Bacteria P ABC-type Zn2 transport system, periplasmic component surface adhesin actF - - - - - - - - - - - - SRR21617311_k127_171179_2 1379698.RBG1_1C00001G1302 1.827e-25 106.0 COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria 2|Bacteria C Cytochrome C oxidase, cbb3-type, subunit III actE - - - - - - - - - - - Cytochrome_CBB3 SRR21617311_k127_1717711_0 1379698.RBG1_1C00001G1453 5.62e-177 558.0 COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria 2|Bacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_3081,iIT341.HP0183 SHMT SRR21617311_k127_1717711_6 300852.55772738 2.065e-29 120.0 COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P PFAM CutA1 divalent ion tolerance protein cutA - - ko:K03926 - - - - ko00000 - - - CutA1 SRR21617311_k127_1717711_5 403833.Pmob_0052 8.087e-30 123.0 COG1661@1|root,COG1661@2|Bacteria,2GDE0@200918|Thermotogae 200918|Thermotogae S Domain of unknown function (DUF296) - - - ko:K06934 - - - - ko00000 - - - DUF296 SRR21617311_k127_1717711_3 706587.Desti_3034 8.01e-58 212.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2MQGS@213462|Syntrophobacterales 28221|Deltaproteobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans SRR21617311_k127_1717711_2 1379698.RBG1_1C00001G1448 2.185e-62 220.0 COG1327@1|root,COG1327@2|Bacteria,2NPEU@2323|unclassified Bacteria 2|Bacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone SRR21617311_k127_1717711_1 1379698.RBG1_1C00001G1447 3.218e-89 301.0 COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria 2|Bacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC SRR21617311_k127_1717711_4 1121101.HMPREF1532_00916 3.702e-42 162.0 COG0330@1|root,COG1073@1|root,COG0330@2|Bacteria,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,2FP0D@200643|Bacteroidia,4AP50@815|Bacteroidaceae 976|Bacteroidetes O COG COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - DLH,DUF3887,Hydrolase_4,Peptidase_S9 SRR21617311_k127_171864_0 269798.CHU_1442 1.597e-88 304.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SRR21617311_k127_1719561_2 742726.HMPREF9448_00739 6.197e-57 225.0 COG4870@1|root,COG4870@2|Bacteria,4PNXD@976|Bacteroidetes,2G101@200643|Bacteroidia 976|Bacteroidetes O Propeptide_C25 - - - - - - - - - - - - Peptidase_C25,Propeptide_C25 SRR21617311_k127_1719561_3 1379698.RBG1_1C00001G0386 7.061e-50 188.0 COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria 2|Bacteria GM Glycosyltransferase like family 2 wbbL - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 SRR21617311_k127_1719561_6 383372.Rcas_1439 5.072e-07 62.0 COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia 32061|Chloroflexia O C-terminal four TMM region of protein-O-mannosyltransferase - - - - - - - - - - - - - SRR21617311_k127_1719561_0 1379698.RBG1_1C00001G0384 5.385e-86 302.0 COG0438@1|root,COG0438@2|Bacteria,2NPP9@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1719561_1 1379698.RBG1_1C00001G0383 2.312e-78 277.0 COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 remC - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1719561_4 1379698.RBG1_1C00001G0382 6.585e-49 188.0 COG5653@1|root,COG5653@2|Bacteria 2|Bacteria M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 SRR21617311_k127_1719561_5 1379698.RBG1_1C00001G0381 3.385e-20 94.0 COG3292@1|root,COG3292@2|Bacteria,2NR3S@2323|unclassified Bacteria 2|Bacteria T Two component regulator propeller - - - - - - - - - - - - Reg_prop SRR21617311_k127_1721940_3 1382356.JQMP01000001_gene1206 6.028e-31 134.0 COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia 189775|Thermomicrobia S BioY family - - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY SRR21617311_k127_1721940_1 857293.CAAU_1747 8.114e-212 673.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,36EI0@31979|Clostridiaceae 186801|Clostridia F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS SRR21617311_k127_1721940_0 1379698.RBG1_1C00001G0805 2.463e-245 771.0 COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria 2|Bacteria C Belongs to the aldehyde dehydrogenase family aldH - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SRR21617311_k127_1721940_2 1379698.RBG1_1C00001G0806 5.559e-43 158.0 COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria 2|Bacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 SRR21617311_k127_1727733_3 1379698.RBG1_1C00001G1179 3.029e-49 183.0 COG0344@1|root,COG0344@2|Bacteria,2NPME@2323|unclassified Bacteria 2|Bacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SRR21617311_k127_1727733_0 1379698.RBG1_1C00001G1178 2.198e-124 406.0 COG0240@1|root,COG0240@2|Bacteria,2NP1N@2323|unclassified Bacteria 2|Bacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N SRR21617311_k127_1727733_5 1379698.RBG1_1C00001G1177 8.334e-28 116.0 COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria 2|Bacteria K helix_turn_helix, mercury resistance ycgE - - ko:K19591,ko:K22491 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR_1 SRR21617311_k127_1727733_1 1379698.RBG1_1C00001G1176 3.713e-71 247.0 COG1216@1|root,COG1216@2|Bacteria,2NS4X@2323|unclassified Bacteria 2|Bacteria S Glycosyl transferase family 2 XK27_08075 - - - - - - - - - - - DUF2062,Glycos_transf_2,GtrA,Lip_A_acyltrans SRR21617311_k127_1727733_2 316067.Geob_3335 2.395e-69 243.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales 28221|Deltaproteobacteria F Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE SRR21617311_k127_1727733_4 1379698.RBG1_1C00001G0505 1.457e-40 162.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SRR21617311_k127_1737377_3 1458275.AZ34_09095 1.568e-07 54.0 2C2YT@1|root,32RB7@2|Bacteria,1RJEN@1224|Proteobacteria,2W1JX@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_1737377_1 1242864.D187_003284 5.815e-54 193.0 COG5646@1|root,COG5646@2|Bacteria 2|Bacteria S Domain of unknown function (DU1801) XK27_02315 - - - - - - - - - - - DUF1801 SRR21617311_k127_1737377_2 484770.UFO1_4296 1.677e-45 175.0 COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes 909932|Negativicutes G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 SRR21617311_k127_1737377_0 290397.Adeh_2418 7.086e-92 315.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase, group 1 - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1743235_0 1379698.RBG1_1C00001G0761 2.16e-117 398.0 COG0008@1|root,COG0008@2|Bacteria,2NNMZ@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SRR21617311_k127_1743235_1 1382359.JIAL01000001_gene2644 9.719e-23 100.0 COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia 204432|Acidobacteriia Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SRR21617311_k127_1745636_1 1379698.RBG1_1C00001G0596 1.455e-150 484.0 COG0265@1|root,COG0265@2|Bacteria,2NQK9@2323|unclassified Bacteria 2|Bacteria O Trypsin degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR21617311_k127_1745636_3 1356852.N008_04505 1.259e-31 129.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase icaB - - - - - - - - - - - Polysacc_deac_1 SRR21617311_k127_1745636_2 1408439.JHXW01000003_gene1521 5.748e-74 265.0 COG0726@1|root,COG0726@2|Bacteria,379I2@32066|Fusobacteria 32066|Fusobacteria G Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_transf_4,Polysacc_deac_1 SRR21617311_k127_1745636_0 1379698.RBG1_1C00001G0379 3.658e-197 626.0 COG0696@1|root,COG0696@2|Bacteria,2NP1Y@2323|unclassified Bacteria 2|Bacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N SRR21617311_k127_1745636_4 118005.AWNK01000013_gene905 8.545e-05 51.0 COG0815@1|root,COG0815@2|Bacteria 2|Bacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SRR21617311_k127_1751453_14 1379698.RBG1_1C00001G1256 4.963e-38 147.0 COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria 2|Bacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO SRR21617311_k127_1751453_12 1379698.RBG1_1C00001G1257 3.358e-42 170.0 COG3166@1|root,COG3166@2|Bacteria 2|Bacteria NU PFAM Fimbrial assembly family protein pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN SRR21617311_k127_1751453_1 1379698.RBG1_1C00001G1258 2.043e-158 505.0 COG4972@1|root,COG4972@2|Bacteria,2NPF6@2323|unclassified Bacteria 2|Bacteria NU Type IV pilus assembly protein PilM; pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 SRR21617311_k127_1751453_21 1255043.TVNIR_1921 8.862e-08 60.0 COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales 135613|Chromatiales U General secretion pathway protein H - - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl SRR21617311_k127_1751453_2 1379698.RBG1_1C00001G1260 5.662e-154 503.0 2DRGI@1|root,33BMN@2|Bacteria 2|Bacteria S PilX N-terminal - - - - - - - - - - - - PilX_N SRR21617311_k127_1751453_15 1379698.RBG1_1C00001G1261 6.113e-30 131.0 COG4966@1|root,COG4966@2|Bacteria 2|Bacteria NU pilus assembly protein PilW pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW SRR21617311_k127_1751453_16 1379698.RBG1_1C00001G1262 1.063e-29 123.0 COG4967@1|root,COG4967@2|Bacteria 2|Bacteria NU type IV pilus modification protein PilV - - - ko:K02458,ko:K02671 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 - - N_methyl SRR21617311_k127_1751453_0 1379698.RBG1_1C00001G1265 3.508e-219 687.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1751453_8 1123504.JQKD01000030_gene4596 2.33e-52 190.0 COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,2VT4V@28216|Betaproteobacteria,4AFU0@80864|Comamonadaceae 28216|Betaproteobacteria O Ergosterol biosynthesis ERG4/ERG24 family - - - - - - - - - - - - PEMT SRR21617311_k127_1751453_9 880073.Calab_2347 6.516e-51 188.0 COG2386@1|root,COG2386@2|Bacteria,2NPHG@2323|unclassified Bacteria 2|Bacteria O CcmB protein ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193,ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iECO111_1330.ECO111_2936,iYL1228.KPN_02080 CcmB SRR21617311_k127_1751453_7 1379698.RBG1_1C00001G0424 1.193e-56 203.0 COG1131@1|root,COG1131@2|Bacteria,2NPQ3@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities ccmA - 3.6.3.41 ko:K01990,ko:K02193 ko02010,map02010 M00254,M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.107 - - ABC_tran SRR21617311_k127_1751453_19 290397.Adeh_2816 2.908e-20 103.0 COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales 28221|Deltaproteobacteria C TIGRFAM cytochrome C family protein - - - - - - - - - - - - GSu_C4xC__C2xCH SRR21617311_k127_1751453_13 378806.STAUR_3725 1.035e-41 165.0 COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,2YUR5@29|Myxococcales 28221|Deltaproteobacteria C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 SRR21617311_k127_1751453_22 398767.Glov_2293 3.175e-07 63.0 2B8GB@1|root,321RF@2|Bacteria,1RIVE@1224|Proteobacteria,42SWQ@68525|delta/epsilon subdivisions,2WPWX@28221|Deltaproteobacteria,43V4P@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_1751453_18 251221.35210810 2.297e-22 99.0 COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria 1117|Cyanobacteria UW Hep Hag repeat protein - - - - - - - - - - - - - SRR21617311_k127_1751453_20 1457250.BBMO01000002_gene2310 6.241e-14 83.0 COG0419@1|root,arCOG00368@2157|Archaea 2157|Archaea L Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - - - - - - - - - - MMPL,PQQ_2,Peptidase_S74,Pkinase SRR21617311_k127_1751453_17 1379698.RBG1_1C00001G0282 3.399e-29 130.0 COG5276@1|root,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria 2|Bacteria M Hep Hag repeat protein - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Calx-beta,LVIVD SRR21617311_k127_1751453_6 1379698.RBG1_1C00001G0425 4.712e-94 314.0 COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria 2|Bacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 SRR21617311_k127_1751453_4 1379698.RBG1_1C00001G0410 5.281e-128 419.0 COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria 2|Bacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 SRR21617311_k127_1751453_3 1379698.RBG1_1C00001G0409 4.074e-128 421.0 COG0743@1|root,COG0743@2|Bacteria,2NNW2@2323|unclassified Bacteria 2|Bacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM0889 DXPR_C,DXP_redisom_C,DXP_reductoisom SRR21617311_k127_1751453_11 314345.SPV1_07621 7.385e-46 172.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria 1224|Proteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768,ko:K09565 ko01503,ko04020,ko04022,ko04217,ko05012,ko05016,ko05145,map01503,map04020,map04022,map04217,map05012,map05016,map05145 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase SRR21617311_k127_1751453_10 1121920.AUAU01000006_gene301 3.599e-47 176.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1751453_5 1379698.RBG1_1C00001G0419 4.775e-125 406.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 ko:K00260,ko:K00261,ko:K00262 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.gdhA ELFV_dehydrog,ELFV_dehydrog_N SRR21617311_k127_1754880_6 1267535.KB906767_gene5535 8.517e-45 177.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria 57723|Acidobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,GAF_3,SpoIIE SRR21617311_k127_1754880_4 1379698.RBG1_1C00001G0929 1.402e-49 182.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB,DinB_2 SRR21617311_k127_1754880_2 1379698.RBG1_1C00001G0930 1.422e-76 257.0 COG0432@1|root,COG0432@2|Bacteria,2NPB7@2323|unclassified Bacteria 2|Bacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SRR21617311_k127_1754880_5 945713.IALB_1083 1.126e-48 193.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Calx-beta,CarboxypepD_reg,LVIVD,TSP_3 SRR21617311_k127_1754880_3 1379698.RBG1_1C00001G1862 4.974e-55 199.0 COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria 2|Bacteria K Sigma-70 region 2 rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_1754880_10 1394178.AWOO02000065_gene118 0.000207 52.0 COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria,4EKFN@85012|Streptosporangiales 201174|Actinobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 SRR21617311_k127_1754880_8 1379698.RBG1_1C00001G1864 2.097e-09 67.0 2DGXT@1|root,2ZXPG@2|Bacteria,2NRPI@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1754880_0 1379698.RBG1_1C00001G1865 9.63e-243 770.0 COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria 2|Bacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 SRR21617311_k127_1754880_1 1379698.RBG1_1C00001G1866 1.242e-140 464.0 COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria 2|Bacteria T Sigma-54 interaction domain fhlA - - ko:K03413,ko:K13589 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506,M00512 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1754880_9 349521.HCH_06386 7.246e-06 56.0 2C721@1|root,33JSW@2|Bacteria,1NIWE@1224|Proteobacteria,1SIEY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_1756514_1 1379698.RBG1_1C00001G1531 6.19e-102 340.0 COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria 2|Bacteria BQ Histone deacetylase domain acuC - - - - - - - - - - - Hist_deacetyl SRR21617311_k127_1756514_0 1379698.RBG1_1C00001G1614 8.897e-141 460.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme metB - 2.5.1.48,4.4.1.11,4.4.1.8 ko:K01739,ko:K01760,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP SRR21617311_k127_1756514_3 204669.Acid345_4403 1.107e-57 212.0 COG2206@1|root,COG2206@2|Bacteria 2|Bacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - HAMP,HD,HD_5 SRR21617311_k127_1756514_4 1303518.CCALI_02387 2.688e-54 195.0 COG0757@1|root,COG0757@2|Bacteria 2|Bacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM0349 DHquinase_II SRR21617311_k127_1756514_2 1158150.KB906241_gene1044 9.295e-79 273.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase SRR21617311_k127_1777795_0 1379698.RBG1_1C00001G0885 2.672e-88 298.0 COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria 2|Bacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338,ko:K08675 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002,ko03029 - - - AAA,LON_substr_bdg,Lon_C SRR21617311_k127_1777795_1 693661.Arcve_1197 1.339e-58 213.0 COG0382@1|root,arCOG00477@2157|Archaea,2XW9S@28890|Euryarchaeota,24617@183980|Archaeoglobi 183980|Archaeoglobi H 4-hydroxybenzoate polyprenyltransferase - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA SRR21617311_k127_1784715_2 1379698.RBG1_1C00001G0608 1.531e-14 74.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N SRR21617311_k127_1784715_1 1379698.RBG1_1C00001G0520 1.085e-106 361.0 COG2208@1|root,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE SRR21617311_k127_1784715_0 1379698.RBG1_1C00001G1211 2.367e-212 668.0 COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria 2|Bacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran SRR21617311_k127_1788737_0 665942.HMPREF1022_00535 1.266e-106 353.0 COG1746@1|root,COG1746@2|Bacteria,1RIPX@1224|Proteobacteria 1224|Proteobacteria J tRNA cytidylyltransferase activity - - - - - - - - - - - - - SRR21617311_k127_1788737_1 1379698.RBG1_1C00001G1442 1.654e-47 175.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family hsp - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SRR21617311_k127_1788737_3 1070774.J07HN4v3_00316 2.237e-10 65.0 COG1520@1|root,arCOG02492@2157|Archaea 2157|Archaea M COG1520 FOG WD40-like repeat - - - - - - - - - - - - PKD,PQQ_3 SRR21617311_k127_1791957_0 1379698.RBG1_1C00001G1233 1.509e-92 311.0 COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 SRR21617311_k127_1801730_1 880073.Calab_2282 2.993e-62 219.0 COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,2NNKI@2323|unclassified Bacteria 2|Bacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - DUF2344,Radical_SAM SRR21617311_k127_1801730_2 880073.Calab_0921 8.914e-25 122.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 SRR21617311_k127_1801730_0 1379698.RBG1_1C00001G0069 1.997e-175 581.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria 2|Bacteria O Subtilase family - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CHU_C,FlgD_ig,PKD,Peptidase_S8 SRR21617311_k127_1803592_0 1379698.RBG1_1C00001G0961 3.537e-300 937.0 COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria 2|Bacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom SRR21617311_k127_1803592_2 696281.Desru_1865 2.048e-57 210.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae 186801|Clostridia D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR21617311_k127_1803592_1 945713.IALB_3000 4.33e-60 211.0 COG5405@1|root,COG5405@2|Bacteria 2|Bacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome SRR21617311_k127_1804191_1 1144275.COCOR_02322 4.152e-68 253.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 SRR21617311_k127_1804191_0 518766.Rmar_1797 1.961e-125 423.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes T Bacterial regulatory protein, Fis family ntrX - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_1805695_0 1379698.RBG1_1C00001G0584 2.265e-216 703.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL SRR21617311_k127_1810349_2 1379698.RBG1_1C00001G1349 2.653e-23 107.0 COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria 2|Bacteria U Branched-chain amino acid transport system / permease component - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SRR21617311_k127_1810349_0 1379698.RBG1_1C00001G1350 6.8e-124 403.0 COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria 2|Bacteria E Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SRR21617311_k127_1810349_1 1379698.RBG1_1C00001G1351 1.431e-114 375.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SRR21617311_k127_1823003_1 338966.Ppro_2404 1.282e-20 93.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales 28221|Deltaproteobacteria H Polyprenyl synthetase ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt SRR21617311_k127_1823003_2 1379698.RBG1_1C00001G1128 5.06e-18 86.0 COG1722@1|root,COG1722@2|Bacteria,2NQ5X@2323|unclassified Bacteria 2|Bacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S SRR21617311_k127_1823003_0 1379698.RBG1_1C00001G1127 2.505e-131 431.0 COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria 2|Bacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6,3.4.21.102 ko:K03601,ko:K03797 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko01002,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 SRR21617311_k127_1825829_0 443144.GM21_2274 5.058e-274 868.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - - ACR_tran SRR21617311_k127_1825829_2 649747.HMPREF0083_01770 3.076e-84 286.0 COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,2729A@186822|Paenibacillaceae 91061|Bacilli S Uncharacterised ArCR, COG2043 - - - - - - - - - - - - DUF169 SRR21617311_k127_1825829_1 1379698.RBG1_1C00001G1216 4.933e-111 369.0 COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria 2|Bacteria H Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D SRR21617311_k127_1825829_3 1379698.RBG1_1C00001G1223 3.294e-67 235.0 COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria 2|Bacteria E FAD dependent oxidoreductase - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO SRR21617311_k127_1826770_1 634177.GLX_19840 5.077e-69 242.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2JQ3A@204441|Rhodospirillales 204441|Rhodospirillales C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpd - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim SRR21617311_k127_1826770_0 1379698.RBG1_1C00001G0508 1.707e-160 513.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family bktB - 2.3.1.16,2.3.1.9 ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00085,M00087,M00088,M00095,M00373,M00374,M00375 R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_182719_2 518766.Rmar_2301 0.0002688 47.0 COG0457@1|root,COG0457@2|Bacteria 518766.Rmar_2301|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SRR21617311_k127_182719_0 1379698.RBG1_1C00001G1345 4.76e-180 581.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - GAF,GAF_2,HATPase_c_2,SSF,SpoIIE SRR21617311_k127_182719_1 945713.IALB_0831 8.531e-47 192.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_2,GAF_3,SpoIIE SRR21617311_k127_1832670_0 1379698.RBG1_1C00001G0395 1.902e-76 264.0 COG0772@1|root,COG0772@2|Bacteria,2NP3P@2323|unclassified Bacteria 2|Bacteria D Belongs to the SEDS family ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 - FTSW_RODA_SPOVE SRR21617311_k127_1832670_1 401526.TcarDRAFT_0182 1.013e-54 199.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4H294@909932|Negativicutes 909932|Negativicutes M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 SRR21617311_k127_1833492_0 62928.azo1490 4.911e-39 156.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV1U@206389|Rhodocyclales 206389|Rhodocyclales T GGDEF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9,Response_reg SRR21617311_k127_1833492_1 443143.GM18_4020 6.061e-10 59.0 COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria 1224|Proteobacteria T Response regulator, receiver - - 2.7.7.65 ko:K02488,ko:K11443 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - Response_reg SRR21617311_k127_1836937_2 1279009.ADICEAN_02760 1.001e-43 164.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 SRR21617311_k127_1836937_1 1379698.RBG1_1C00001G0244 7.722e-69 236.0 COG1764@1|root,COG1764@2|Bacteria,2NQ0N@2323|unclassified Bacteria 2|Bacteria O OsmC-like protein osmC GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - ko:K04063 - - - - ko00000 - - - OsmC SRR21617311_k127_1836937_0 1379698.RBG1_1C00001G1726 8.582e-86 303.0 29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria 2|Bacteria S Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi SRR21617311_k127_1836937_3 1123376.AUIU01000016_gene334 1.832e-39 154.0 COG1947@1|root,COG1947@2|Bacteria,3J0N1@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N SRR21617311_k127_1840853_1 195522.BD01_1491 3.747e-53 202.0 COG0438@1|root,arCOG01411@2157|Archaea,2Y8B0@28890|Euryarchaeota 28890|Euryarchaeota M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1840853_2 1485545.JQLW01000008_gene1987 3.497e-33 140.0 COG4627@1|root,COG4627@2|Bacteria,1RKW8@1224|Proteobacteria 1224|Proteobacteria S Pfam Methyltransferase - - - - - - - - - - - - Methyltransf_11 SRR21617311_k127_1840853_3 452637.Oter_1766 4.284e-30 136.0 COG2244@1|root,COG2244@2|Bacteria,46T3R@74201|Verrucomicrobia 74201|Verrucomicrobia S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SRR21617311_k127_1840853_4 243365.CV_0772 4.613e-12 78.0 COG3206@1|root,COG3206@2|Bacteria,1QUY4@1224|Proteobacteria,2VMTT@28216|Betaproteobacteria 28216|Betaproteobacteria M Chain length determinant protein - - - - - - - - - - - - GNVR,Wzz SRR21617311_k127_1840853_0 269799.Gmet_2184 3.539e-118 411.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2WJ83@28221|Deltaproteobacteria,43U6W@69541|Desulfuromonadales 28221|Deltaproteobacteria M Capsule biosynthesis GfcC - - - - - - - - - - - - Caps_synth_GfcC,Poly_export,SLBB SRR21617311_k127_1840853_5 1165096.ARWF01000001_gene1201 9.26e-07 55.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,2KKTE@206350|Nitrosomonadales 206350|Nitrosomonadales L TIGRFAM DNA repair protein RadC - - - ko:K03630 - - - - ko00000 - - - RadC SRR21617311_k127_1844878_1 1379698.RBG1_1C00001G0069 1.043e-56 207.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria 2|Bacteria O Subtilase family - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CHU_C,FlgD_ig,PKD,Peptidase_S8 SRR21617311_k127_1844878_0 1379698.RBG1_1C00001G0069 2.397e-138 461.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria 2|Bacteria O Subtilase family - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CHU_C,FlgD_ig,PKD,Peptidase_S8 SRR21617311_k127_1850698_3 518766.Rmar_1577 2.8e-17 91.0 COG2834@1|root,COG2834@2|Bacteria,4PESZ@976|Bacteroidetes,1FJJM@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M outer membrane lipoprotein carrier protein LolA - - - ko:K03634 - - - - ko00000 - - - LolA SRR21617311_k127_1850698_0 1379698.RBG1_1C00001G0866 4.683e-215 692.0 COG1674@1|root,COG1674@2|Bacteria,2NNVB@2323|unclassified Bacteria 2|Bacteria D Ftsk_gamma ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SRR21617311_k127_1850698_2 1379698.RBG1_1C00001G0865 2.643e-30 121.0 COG0776@1|root,COG0776@2|Bacteria,2NPTH@2323|unclassified Bacteria 2|Bacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530,ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SRR21617311_k127_1850698_1 1379698.RBG1_1C00001G0864 3.128e-85 297.0 COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria 2|Bacteria M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744,ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC,OstA,OstA_C SRR21617311_k127_1852153_0 1379698.RBG1_1C00001G1038 6.26e-73 259.0 COG0859@1|root,COG0859@2|Bacteria,2NPXQ@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_1852153_1 1379698.RBG1_1C00001G1037 5.968e-21 95.0 COG0463@1|root,COG0463@2|Bacteria,2NPA5@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 kdtX - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 SRR21617311_k127_1854667_1 604331.AUHY01000058_gene1343 3.782e-60 214.0 2CEY7@1|root,2Z8CG@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - - SRR21617311_k127_1854667_0 1379698.RBG1_1C00001G1551 0.0 1019.0 COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria 2|Bacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB SRR21617311_k127_1854667_4 1379698.RBG1_1C00001G1830 1.481e-25 112.0 COG1399@1|root,COG1399@2|Bacteria,2NPVD@2323|unclassified Bacteria 2|Bacteria S Uncharacterized ACR, COG1399 yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 SRR21617311_k127_1854667_3 1379698.RBG1_1C00001G1829 1.468e-26 109.0 COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria 2|Bacteria J Ribosomal L32p protein family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p SRR21617311_k127_1854667_2 1379698.RBG1_1C00001G1828 3.344e-51 187.0 COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria 2|Bacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SRR21617311_k127_186669_0 1379698.RBG1_1C00001G1445 7.364e-155 502.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - BSP,Bac_surface_Ag,PD40,Peptidase_MA_2 SRR21617311_k127_1869548_0 945713.IALB_2638 8.59e-197 628.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SRR21617311_k127_1869993_0 1379698.RBG1_1C00001G0698 5e-324 1005.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria 2|Bacteria C Malic enzyme, NAD binding domain maeB GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1637 Malic_M,PTA_PTB,malic SRR21617311_k127_1869993_1 1379698.RBG1_1C00001G0849 4.352e-31 126.0 COG1959@1|root,COG1959@2|Bacteria,2NQ8B@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulator, BadM Rrf2 family iscR - - - - - - - - - - - Rrf2 SRR21617311_k127_1872040_0 880073.Calab_3296 4.318e-24 109.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SRR21617311_k127_1872040_1 1047013.AQSP01000100_gene582 5.159e-21 96.0 COG1708@1|root,COG1708@2|Bacteria,2NQ4R@2323|unclassified Bacteria 2|Bacteria S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 SRR21617311_k127_1887045_0 1379698.RBG1_1C00001G0466 2.096e-126 411.0 COG2008@1|root,COG2008@2|Bacteria,2NNMP@2323|unclassified Bacteria 2|Bacteria E aromatic amino acid beta-eliminating lyase threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase SRR21617311_k127_1887045_1 1379698.RBG1_1C00001G1492 1.46e-21 96.0 COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria 2|Bacteria K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SRR21617311_k127_1890429_2 1379698.RBG1_1C00001G1347 1.429e-53 192.0 COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria 2|Bacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SRR21617311_k127_1890429_1 913865.DOT_3189 5.027e-99 330.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,260FQ@186807|Peptococcaceae 186801|Clostridia E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SRR21617311_k127_1890429_0 1379698.RBG1_1C00001G1349 2.193e-131 428.0 COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria 2|Bacteria U Branched-chain amino acid transport system / permease component - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SRR21617311_k127_1904968_1 1379698.RBG1_1C00001G0175 7.685e-37 146.0 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,2NRE7@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02022,ko:K16922,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko01002,ko02000 3.A.1.112,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD SRR21617311_k127_1904968_0 1379698.RBG1_1C00001G0071 4.249e-135 441.0 COG0475@1|root,COG0475@2|Bacteria 2|Bacteria P glutathione-regulated potassium exporter activity kefB - - - - - - - - - - - Na_H_Exchanger,PTS_EIIA_2 SRR21617311_k127_1915923_5 686340.Metal_1232 6.5e-27 114.0 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales 135618|Methylococcales L Protein of unknown function (DUF559) - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - DUF559 SRR21617311_k127_1915923_0 1379698.RBG1_1C00001G1870 1.082e-158 509.0 COG0232@1|root,COG0232@2|Bacteria,2NP3S@2323|unclassified Bacteria 2|Bacteria F Phosphohydrolase-associated domain dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc SRR21617311_k127_1915923_4 635013.TherJR_2462 5.694e-32 139.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,260KF@186807|Peptococcaceae 186801|Clostridia L TIGRFAM DNA polymerase III, delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta SRR21617311_k127_1915923_3 1379698.RBG1_1C00001G0627 2.968e-34 139.0 COG1595@1|root,COG1595@2|Bacteria,2NQ4E@2323|unclassified Bacteria 2|Bacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_1915923_6 58123.JOFJ01000016_gene4067 0.000808 51.0 COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria,4EKFN@85012|Streptosporangiales 201174|Actinobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 SRR21617311_k127_1915923_1 1379698.RBG1_1C00001G0062 5.968e-48 179.0 COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT SRR21617311_k127_1916939_1 1379698.RBG1_1C00001G1848 4.307e-100 334.0 COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria 2|Bacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD SRR21617311_k127_1916939_2 1379698.RBG1_1C00001G1847 6.433e-36 143.0 COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria 2|Bacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH SRR21617311_k127_1916939_0 1379698.RBG1_1C00001G1846 1.719e-250 797.0 COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria 2|Bacteria M Surface antigen bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SRR21617311_k127_1916939_3 1379698.RBG1_1C00001G1845 1.864e-29 121.0 COG0261@1|root,COG0261@2|Bacteria,2NPSX@2323|unclassified Bacteria 2|Bacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p SRR21617311_k127_1916939_4 383372.Rcas_2505 4.379e-16 92.0 COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - SRR21617311_k127_191797_1 1267534.KB906759_gene1791 1.881e-38 146.0 2CEY7@1|root,2Z8CG@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - - SRR21617311_k127_191797_0 1303518.CCALI_00474 2.169e-217 683.0 COG1053@1|root,COG1053@2|Bacteria 2|Bacteria C succinate dehydrogenase sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SRR21617311_k127_1921261_0 1379698.RBG1_1C00001G0122 7.801e-312 965.0 COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria 2|Bacteria G MutL protein - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N,MutL SRR21617311_k127_1921261_1 1379698.RBG1_1C00001G0125 1.018e-29 126.0 2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1921261_2 1379698.RBG1_1C00001G0126 4.175e-28 119.0 2C451@1|root,2ZRAU@2|Bacteria,2NS2X@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1921261_4 710696.Intca_0038 0.000945 43.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SRR21617311_k127_1931529_0 1379698.RBG1_1C00001G1743 1.577e-108 355.0 COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria 2|Bacteria NU Type II secretion system (T2SS), protein E, N-terminal domain pilB - - ko:K02454,ko:K02504,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N SRR21617311_k127_1931529_4 1379698.RBG1_1C00001G1744 1.876e-67 235.0 COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria 2|Bacteria S Roadblock/LC7 domain mglB - - - - - - - - - - - Robl_LC7 SRR21617311_k127_1931529_2 1379698.RBG1_1C00001G1745 7.373e-88 302.0 COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria 2|Bacteria K - Catabolite gene activator and regulatory subunit of cAMP-dependent protein mglA GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - ko:K06883 - - - - ko00000 - - - Arf,DUF697,MMR_HSR1 SRR21617311_k127_1931529_7 1379698.RBG1_1C00001G1746 5.607e-41 154.0 COG2018@1|root,COG2018@2|Bacteria,2NRUR@2323|unclassified Bacteria 2|Bacteria S Roadblock/LC7 domain - - - ko:K07131 - - - - ko00000 - - - Robl_LC7 SRR21617311_k127_1931529_6 1379698.RBG1_1C00001G1748 4.29e-47 183.0 COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria 2|Bacteria M Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_1931529_1 1379698.RBG1_1C00001G1750 2.621e-97 332.0 COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - DUF4388 SRR21617311_k127_1931529_3 1379698.RBG1_1C00001G1751 1.399e-75 281.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria 2|Bacteria U Metallo-beta-lactamase superfamily comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B SRR21617311_k127_1931529_5 1379698.RBG1_1C00001G1752 4.34e-57 214.0 COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria 2|Bacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SRR21617311_k127_1938061_5 1379698.RBG1_1C00001G1487 1.042e-49 187.0 COG2264@1|root,COG2264@2|Bacteria,2NPP7@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA SRR21617311_k127_1938061_2 1304284.L21TH_1367 4.168e-117 388.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG SRR21617311_k127_1938061_4 661478.OP10G_4004 7.362e-53 196.0 COG5588@1|root,COG5588@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 SRR21617311_k127_1938061_6 1379698.RBG1_1C00001G1490 2.861e-44 168.0 COG0576@1|root,COG0576@2|Bacteria,2NPSS@2323|unclassified Bacteria 2|Bacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE SRR21617311_k127_1938061_1 1379698.RBG1_1C00001G1491 1.127e-126 413.0 COG1420@1|root,COG1420@2|Bacteria,2NPAK@2323|unclassified Bacteria 2|Bacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HTH_DeoR,HrcA,HrcA_DNA-bdg SRR21617311_k127_1938061_0 1379698.RBG1_1C00001G1239 9.92e-157 504.0 COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria 2|Bacteria P Natural resistance-associated macrophage protein - - - - - - - - - - - iHN637.CLJU_RS07840 Nramp SRR21617311_k127_1938061_3 635013.TherJR_1583 1.974e-62 225.0 COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae 186801|Clostridia C Fe-S oxidoreductase - - - - - - - - - - - - DUF512,PDZ SRR21617311_k127_1938461_1 1379698.RBG1_1C00001G1459 8.162e-23 99.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_1938461_0 1379698.RBG1_1C00001G1460 7.25e-101 333.0 COG2057@1|root,COG2057@2|Bacteria,2NP63@2323|unclassified Bacteria 2|Bacteria I Coenzyme A transferase scoB - 2.8.3.12,2.8.3.5 ko:K01027,ko:K01029,ko:K01040 ko00072,ko00280,ko00643,ko00650,ko01120,map00072,map00280,map00643,map00650,map01120 - R00410,R04000,R05509 RC00012,RC00014,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SRR21617311_k127_1942593_3 1089553.Tph_c12950 1.425e-06 55.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42FW0@68295|Thermoanaerobacterales 186801|Clostridia M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_1942593_1 1209989.TepiRe1_0702 1.263e-136 449.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,42FS1@68295|Thermoanaerobacterales 186801|Clostridia E PFAM fumarate lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 SRR21617311_k127_1942593_2 1128421.JAGA01000003_gene2928 1.884e-34 138.0 COG3059@1|root,COG3059@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - DUF417,DoxX SRR21617311_k127_1942593_0 1379698.RBG1_1C00001G0430 1.036e-293 909.0 COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria 2|Bacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C SRR21617311_k127_1949363_1 1379698.RBG1_1C00001G1716 1.231e-80 283.0 COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria 2|Bacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SRR21617311_k127_1949363_0 1379698.RBG1_1C00001G1715 5.592e-96 318.0 COG0740@1|root,COG0740@2|Bacteria,2NNPA@2323|unclassified Bacteria 2|Bacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease SRR21617311_k127_1949363_2 313595.P700755_001141 6.814e-25 113.0 COG0739@1|root,COG0739@2|Bacteria,4NJUQ@976|Bacteroidetes,1HZ3C@117743|Flavobacteriia 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - DUF3887,Peptidase_M23 SRR21617311_k127_1950724_0 1379698.RBG1_1C00001G0808 1.766e-227 724.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NQNK@2323|unclassified Bacteria 2|Bacteria EU Peptidase S9 prolyl oligopeptidase active site - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N SRR21617311_k127_1950724_2 1379698.RBG1_1C00001G0120 2.657e-56 198.0 28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - SRR21617311_k127_1955093_0 1379698.RBG1_1C00001G1819 2.127e-168 557.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_1955093_1 1379698.RBG1_1C00001G1818 4.83e-83 289.0 COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SRR21617311_k127_1955093_2 1379698.RBG1_1C00001G1817 1.701e-14 77.0 COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria 2|Bacteria E aminopeptidase N - - - - - - - - - - - - CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B SRR21617311_k127_1960432_1 398767.Glov_2172 1.218e-91 308.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria 28221|Deltaproteobacteria M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 SRR21617311_k127_1960432_7 867903.ThesuDRAFT_00973 0.0001966 51.0 COG2834@1|root,COG2834@2|Bacteria,1UB6P@1239|Firmicutes,24DTV@186801|Clostridia 186801|Clostridia M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - MucB_RseB SRR21617311_k127_1960432_0 1379698.RBG1_1C00001G0542 3.95e-258 809.0 COG0504@1|root,COG0504@2|Bacteria,2NNVG@2323|unclassified Bacteria 2|Bacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 CTP_synth_N,GATase SRR21617311_k127_1960432_3 748449.Halha_2419 6.332e-68 239.0 COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales 186801|Clostridia M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 SRR21617311_k127_1960432_6 706587.Desti_2940 2.267e-20 94.0 COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - iAF987.Gmet_0076 Glu-tRNAGln SRR21617311_k127_1960432_2 1379698.RBG1_1C00001G1630 9.627e-76 268.0 COG1230@1|root,COG1230@2|Bacteria,2NPHK@2323|unclassified Bacteria 2|Bacteria P Cation efflux family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer SRR21617311_k127_1960432_4 1210046.B277_08255 1.48e-25 119.0 2EG29@1|root,339U9@2|Bacteria,2GPUY@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (Hypoth_ymh) - - - - - - - - - - - - Hypoth_Ymh SRR21617311_k127_1960432_5 309807.SRU_2828 1.58e-21 100.0 2DBIE@1|root,32ZYG@2|Bacteria,4PM6T@976|Bacteroidetes,1FJJR@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_1960432_8 29850.GGTG_07040T0 0.0007844 42.0 2DJDP@1|root,2S60G@2759|Eukaryota,38GS4@33154|Opisthokonta,3P12J@4751|Fungi,3QJEH@4890|Ascomycota,211JA@147550|Sordariomycetes,41NF6@639021|Magnaporthales 4751|Fungi S zinc finger - - - - - - - - - - - - - SRR21617311_k127_1964834_0 1379698.RBG1_1C00001G0659 4.566e-237 738.0 COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SRR21617311_k127_1964834_3 469615.FGAG_01572 1.519e-09 62.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin SRR21617311_k127_1964834_4 330214.NIDE1373 8.048e-08 57.0 COG2161@1|root,COG2161@2|Bacteria 2|Bacteria D toxin-antitoxin pair type II binding relF GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 ko:K08591,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 - - - PhdYeFM_antitox SRR21617311_k127_1964834_1 1379698.RBG1_1C00001G1772 1.102e-36 151.0 COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SRR21617311_k127_1964834_2 247490.KSU1_C0864 5.16e-18 91.0 COG0457@1|root,COG0457@2|Bacteria,2IWZ3@203682|Planctomycetes 203682|Planctomycetes S Oxygen tolerance - - - - - - - - - - - - BatD SRR21617311_k127_196939_0 945713.IALB_1831 3.383e-47 195.0 COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CelD_N,Glyco_hydro_9 SRR21617311_k127_1972023_1 1379698.RBG1_1C00001G1642 3.969e-115 381.0 COG0029@1|root,COG0029@2|Bacteria,2NNMD@2323|unclassified Bacteria 2|Bacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C SRR21617311_k127_1972023_0 1379698.RBG1_1C00001G1641 9.356e-209 662.0 COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria 2|Bacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 - - iLJ478.TM1820 GATase,GMP_synt_C,NAD_synthase SRR21617311_k127_1972023_2 1379698.RBG1_1C00001G1640 7.188e-77 268.0 COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_1977434_1 1379698.RBG1_1C00001G0378 2.328e-117 385.0 COG0150@1|root,COG0150@2|Bacteria,2NNUJ@2323|unclassified Bacteria 2|Bacteria F AIR synthase related protein, N-terminal domain purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1844,iECSF_1327.ECSF_2340 AIRS,AIRS_C SRR21617311_k127_1977434_2 1379698.RBG1_1C00001G0377 1.241e-100 335.0 COG3294@1|root,COG3294@2|Bacteria,2NQWX@2323|unclassified Bacteria 2|Bacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K09163 - - - - ko00000 - - - HD SRR21617311_k127_1977434_0 1379698.RBG1_1C00001G0417 4.342e-168 544.0 COG1198@1|root,COG1198@2|Bacteria,2NNQ3@2323|unclassified Bacteria 2|Bacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII SRR21617311_k127_198180_2 316067.Geob_3739 1.335e-13 80.0 COG3880@1|root,COG3880@2|Bacteria 2|Bacteria E PFAM UvrB UvrC protein mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K08999,ko:K19405,ko:K19411 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - Cytochrom_CIII,Cytochrome_C7,UVR SRR21617311_k127_198180_5 1121918.ARWE01000001_gene1133 6.106e-11 71.0 COG4380@1|root,COG4380@2|Bacteria 2|Bacteria D Lipoprotein - - - - - - - - - - - - CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2 SRR21617311_k127_198180_1 290397.Adeh_3071 2.375e-14 81.0 COG4380@1|root,COG4380@2|Bacteria,1NJYS@1224|Proteobacteria,42X1E@68525|delta/epsilon subdivisions,2WTEE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Putative bacterial lipoprotein (DUF799) - - - - - - - - - - - - DUF799 SRR21617311_k127_198180_3 6500.XP_005094396.1 1.403e-12 79.0 KOG2177@1|root,KOG2177@2759|Eukaryota,38F95@33154|Opisthokonta,3BA7J@33208|Metazoa,3CZWX@33213|Bilateria 33208|Metazoa O tripartite motif containing 71, E3 ubiquitin protein ligase nhl-1 GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564 2.3.2.27 ko:K11997,ko:K12035 ko05206,map05206 - - - ko00000,ko00001,ko01000,ko03019,ko04121 - - - NHL,zf-B_box,zf-C3HC4,zf-RING_UBOX SRR21617311_k127_198180_4 161156.JQKW01000006_gene1249 1.632e-11 76.0 28WYN@1|root,2ZIXP@2|Bacteria,2GHSR@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria - - - - - - - - - - - - - - Paired_CXXCH_1 SRR21617311_k127_198180_0 877455.Metbo_0048 4.34e-82 281.0 COG0477@1|root,arCOG02682@2157|Archaea,2XWP6@28890|Euryarchaeota,23PB6@183925|Methanobacteria 183925|Methanobacteria G Sugar (and other) transporter - - - - - - - - - - - - - SRR21617311_k127_198308_5 235985.BBPN01000007_gene3317 1.402e-18 89.0 COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,2NH9M@228398|Streptacidiphilus 201174|Actinobacteria S Beta-lactamase superfamily domain rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 SRR21617311_k127_198308_2 945713.IALB_1953 1.58e-33 138.0 COG2353@1|root,COG2353@2|Bacteria 2|Bacteria O YceI-like domain - - - - - - - - - - - - YceI SRR21617311_k127_198308_1 1379698.RBG1_1C00001G1804 4.033e-53 190.0 2E8AI@1|root,332PD@2|Bacteria,2NRHQ@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_198308_6 1379698.RBG1_1C00001G1805 1.004e-15 79.0 COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria 2|Bacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SRR21617311_k127_198308_0 1379698.RBG1_1C00001G1807 3.854e-103 341.0 COG0047@1|root,COG0047@2|Bacteria,2NP46@2323|unclassified Bacteria 2|Bacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 SRR21617311_k127_198308_4 349102.Rsph17025_0712 7.743e-21 94.0 COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,1FC0Z@1060|Rhodobacter 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS SRR21617311_k127_200160_3 945713.IALB_1642 3.47e-08 58.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - CHU_C,HYR,SLH,VCBS SRR21617311_k127_200160_2 521011.Mpal_1345 1.479e-09 68.0 COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia 224756|Methanomicrobia P PFAM NHL repeat containing protein - - - - - - - - - - - - FlgD_ig,NHL SRR21617311_k127_200160_0 204669.Acid345_3322 1.463e-17 96.0 COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia 204432|Acidobacteriia KT Peptidase M56 - - - - - - - - - - - - - SRR21617311_k127_200160_1 234267.Acid_1509 4.936e-13 81.0 COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria 57723|Acidobacteria KT Peptidase M56 - - - - - - - - - - - - - SRR21617311_k127_2004430_2 1379698.RBG1_1C00001G0897 4.775e-118 388.0 COG1924@1|root,COG1924@2|Bacteria,2NPG0@2323|unclassified Bacteria 2|Bacteria I BadF/BadG/BcrA/BcrD ATPase family hgdC - 1.3.7.8 ko:K04114 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG SRR21617311_k127_2004430_1 1379698.RBG1_1C00001G0896 6.029e-119 386.0 COG1924@1|root,COG1924@2|Bacteria,2NPG0@2323|unclassified Bacteria 2|Bacteria I BadF/BadG/BcrA/BcrD ATPase family - - 1.3.7.8 ko:K04115 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG SRR21617311_k127_2004430_0 1379698.RBG1_1C00001G0895 2.238e-254 785.0 COG1775@1|root,COG1775@2|Bacteria 2|Bacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D SRR21617311_k127_2006002_6 1548153.LR59_04270 7.531e-08 53.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2YMES@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_2006002_4 1499967.BAYZ01000028_gene1230 5.647e-59 214.0 COG0726@1|root,COG0726@2|Bacteria,2NPFG@2323|unclassified Bacteria 2|Bacteria G Domain of unknown function (DUF3473) - - - - - - - - - - - - DUF3473,Polysacc_deac_1 SRR21617311_k127_2006002_5 459349.CLOAM1842 6.543e-32 134.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_23,Methyltransf_31 SRR21617311_k127_2006002_0 1379698.RBG1_1C00001G0509 2e-288 900.0 COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria 2|Bacteria C synthetase (ADP forming), alpha - - 6.2.1.13 ko:K01905,ko:K09181,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig SRR21617311_k127_2006002_2 264732.Moth_0874 4.641e-99 332.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,42FQ5@68295|Thermoanaerobacterales 186801|Clostridia V pfam abc - - - ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC_tran SRR21617311_k127_2006002_3 1379698.RBG1_1C00001G0299 1.913e-87 295.0 COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria 2|Bacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - LysM,Sod_Fe_C,Sod_Fe_N SRR21617311_k127_2006002_1 1379698.RBG1_1C00001G1186 4.723e-144 466.0 COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria 2|Bacteria E Threonine synthase MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR21617311_k127_2010316_3 1379698.RBG1_1C00001G0211 1.389e-50 191.0 COG0457@1|root,COG0457@2|Bacteria,2NQ8S@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_2010316_4 266264.Rmet_5690 1.132e-21 106.0 2DBPG@1|root,2ZA96@2|Bacteria,1QVNF@1224|Proteobacteria,2VP5D@28216|Betaproteobacteria,1K3DF@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4382) - - - - - - - - - - - - CarboxypepD_reg,DUF4382 SRR21617311_k127_2010316_2 1379698.RBG1_1C00001G1343 3.713e-89 304.0 COG2199@1|root,COG2199@2|Bacteria,2NS3Z@2323|unclassified Bacteria 2|Bacteria T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,HAMP SRR21617311_k127_2010316_1 1379698.RBG1_1C00001G1344 5.223e-91 310.0 COG4974@1|root,COG4974@2|Bacteria,2NNN8@2323|unclassified Bacteria 2|Bacteria L Phage integrase, N-terminal SAM-like domain xerC - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR21617311_k127_2010316_0 449447.MAE_55980 2.222e-266 829.0 COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,1G70A@1117|Cyanobacteria 1117|Cyanobacteria V Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HSDR_N_2,N6_Mtase SRR21617311_k127_2011371_0 1121430.JMLG01000001_gene2276 1.639e-67 240.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25ZY0@186807|Peptococcaceae 186801|Clostridia J MiaB-like tRNA modifying enzyme yqeV - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SRR21617311_k127_2011371_2 871968.DESME_02605 4.579e-17 88.0 COG1246@1|root,COG1246@2|Bacteria,1V9D3@1239|Firmicutes,25DDN@186801|Clostridia 186801|Clostridia E Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SRR21617311_k127_2011371_1 1379698.RBG1_1C00001G0820 2.108e-48 177.0 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SRR21617311_k127_2011411_0 1379698.RBG1_1C00001G0446 3.306e-137 445.0 COG3869@1|root,COG3869@2|Bacteria,2NR28@2323|unclassified Bacteria 2|Bacteria E ATP:guanido phosphotransferase, C-terminal catalytic domain mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 ko:K00933,ko:K00934,ko:K19405 ko00330,ko01100,map00330,map01100 M00047 R00554,R01881,R11090 RC00002,RC00203 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ATP-gua_Ptrans SRR21617311_k127_2011411_1 1379698.RBG1_1C00001G0447 1.15e-44 166.0 COG3880@1|root,COG3880@2|Bacteria,2NRIE@2323|unclassified Bacteria 2|Bacteria S UvrB/uvrC motif CP_0046 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405,ko:K19411 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - GSu_C4xC__C2xCH,UVR SRR21617311_k127_2014762_1 1379698.RBG1_1C00001G1496 7.64e-65 226.0 COG2065@1|root,COG2065@2|Bacteria,2NPF2@2323|unclassified Bacteria 2|Bacteria F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran SRR21617311_k127_2014762_0 1379698.RBG1_1C00001G1495 1.214e-127 413.0 COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria 2|Bacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N SRR21617311_k127_2018326_5 324925.Ppha_1063 0.0002535 46.0 COG1947@1|root,COG1947@2|Bacteria,1FDN3@1090|Chlorobi 1090|Chlorobi F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N SRR21617311_k127_2018326_4 1379698.RBG1_1C00001G0639 7.657e-29 118.0 COG2088@1|root,COG2088@2|Bacteria,2NQ05@2323|unclassified Bacteria 2|Bacteria D SpoVG spoVG - - ko:K06412 - - - - ko00000 - - - SpoVG SRR21617311_k127_2018326_2 929556.Solca_1278 4.638e-73 250.0 COG3631@1|root,COG3631@2|Bacteria,4NP0M@976|Bacteroidetes,1IY2J@117747|Sphingobacteriia 976|Bacteroidetes S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL SRR21617311_k127_2018326_1 1379698.RBG1_1C00001G1676 5.676e-143 461.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2NPBE@2323|unclassified Bacteria 2|Bacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR SRR21617311_k127_2018326_0 1379698.RBG1_1C00001G0643 3.764e-143 462.0 COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria 2|Bacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2848 Pribosyl_synth,Pribosyltran_N SRR21617311_k127_2018326_3 1379698.RBG1_1C00001G0172 7.447e-40 153.0 COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria 2|Bacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SRR21617311_k127_2018942_2 485914.Hmuk_2893 7.867e-07 57.0 COG1246@1|root,arCOG00840@2157|Archaea,2XUNS@28890|Euryarchaeota,23U6T@183963|Halobacteria 183963|Halobacteria E COG1246 N-acetylglutamate synthase and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 SRR21617311_k127_2018942_0 1313301.AUGC01000001_gene1411 3.882e-236 739.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes 976|Bacteroidetes I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SRR21617311_k127_2018942_1 1379698.RBG1_1C00001G1472 1.394e-93 313.0 COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria 2|Bacteria S Metallo-beta-lactamase superfamily ytnP - - - - - - - - - - - Lactamase_B SRR21617311_k127_2022818_0 1379698.RBG1_1C00001G0078 0.0 1116.0 COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria 2|Bacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547,iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536 ACR_tran SRR21617311_k127_2022818_1 1173028.ANKO01000189_gene393 0.0001077 50.0 2CEMI@1|root,331MB@2|Bacteria,1G8M0@1117|Cyanobacteria,1HDYV@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2024590_3 459349.CLOAM1198 1.219e-10 64.0 2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2024590_1 671143.DAMO_0350 4.003e-64 229.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2024590_2 247490.KSU1_B0649 1.013e-40 161.0 29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SRR21617311_k127_2024590_0 1379698.RBG1_1C00001G0119 1.372e-103 349.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2030739_4 1519464.HY22_02995 1.502e-14 85.0 COG0823@1|root,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N SRR21617311_k127_2030739_0 1379698.RBG1_1C00001G1507 5.098e-113 376.0 COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria 2|Bacteria M pfkB family carbohydrate kinase rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB SRR21617311_k127_2030739_1 485913.Krac_9502 9.059e-81 281.0 COG0604@1|root,COG0604@2|Bacteria 2|Bacteria C NADPH:quinone reductase activity fadB5 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 SRR21617311_k127_2030739_2 667014.Thein_1023 1.173e-49 181.0 COG0388@1|root,COG0615@1|root,COG0388@2|Bacteria,COG0615@2|Bacteria,2GHDJ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria IM Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CN_hydrolase,CTP_transf_like SRR21617311_k127_2030739_3 1192034.CAP_4458 1.017e-15 88.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,43CW4@68525|delta/epsilon subdivisions,2WVX0@28221|Deltaproteobacteria,2YVBV@29|Myxococcales 28221|Deltaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - SRR21617311_k127_2039590_0 1379698.RBG1_1C00001G0983 1.344e-169 554.0 COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria 2|Bacteria J Ribonuclease E/G family rng - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 SRR21617311_k127_2039590_1 1379698.RBG1_1C00001G0982 1.488e-90 307.0 COG0223@1|root,COG0223@2|Bacteria,2NP7J@2323|unclassified Bacteria 2|Bacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N SRR21617311_k127_2039590_2 1379698.RBG1_1C00001G0981 7.242e-47 173.0 COG0242@1|root,COG0242@2|Bacteria,2NPNH@2323|unclassified Bacteria 2|Bacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 ko:K01462,ko:K07391 - - - - ko00000,ko01000 - - - Pep_deformylase SRR21617311_k127_2039590_3 1379698.RBG1_1C00001G0980 2.044e-30 122.0 COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria 2|Bacteria U Preprotein translocase, YajC yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC SRR21617311_k127_2046161_0 1379698.RBG1_1C00001G0686 1.031e-70 243.0 COG1252@1|root,COG1252@2|Bacteria,2NP3T@2323|unclassified Bacteria 2|Bacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase ndh GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU12290,iYO844.BSU32100 Pyr_redox_2 SRR21617311_k127_2046161_2 709991.Odosp_3098 5.443e-31 135.0 COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,2FN7X@200643|Bacteroidia,22XMH@171551|Porphyromonadaceae 976|Bacteroidetes S Belongs to the multicopper oxidase YfiH RL5 family - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 SRR21617311_k127_2047334_0 1120973.AQXL01000099_gene3276 9.923e-195 620.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,2798N@186823|Alicyclobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD SRR21617311_k127_2055079_0 1379698.RBG1_1C00001G1627 3.043e-288 892.0 COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SRR21617311_k127_2056130_0 643867.Ftrac_3196 2.908e-59 215.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia 976|Bacteroidetes H Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA SRR21617311_k127_2056130_3 1453503.AU05_03180 5.472e-37 149.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1YCYB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D ATP-binding protein ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran SRR21617311_k127_2056130_5 1379698.RBG1_1C00001G0314 5.516e-22 107.0 COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria 2|Bacteria D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - ko:K09811,ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX SRR21617311_k127_2056130_2 1379698.RBG1_1C00001G0315 5.012e-46 184.0 COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria 2|Bacteria D Peptidase family M23 envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SRR21617311_k127_2056130_1 1379698.RBG1_1C00001G0316 6.973e-51 195.0 COG2812@1|root,COG2812@2|Bacteria,2NPH0@2323|unclassified Bacteria 2|Bacteria L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C SRR21617311_k127_2056130_4 1379698.RBG1_1C00001G0428 7.006e-28 115.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - ko:K20952 ko05111,map05111 - - - ko00000,ko00001 - - - B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS SRR21617311_k127_2056130_6 886293.Sinac_4765 0.0007589 51.0 COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes 203682|Planctomycetes U Pkd domain containing protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - - SRR21617311_k127_2056137_3 485914.Hmuk_0138 1.759e-09 66.0 COG3391@1|root,arCOG14289@1|root,arCOG02562@2157|Archaea,arCOG14289@2157|Archaea,2XX0P@28890|Euryarchaeota,23VHS@183963|Halobacteria 183963|Halobacteria S FG-GAP repeat - - - - - - - - - - - - FG-GAP SRR21617311_k127_2056137_0 1303518.CCALI_02107 9.76e-187 600.0 COG1543@1|root,COG1543@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 57 family - GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K03406,ko:K16149 ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko02035 - GH57 - DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2056137_2 1379698.RBG1_1C00001G1508 2.948e-41 157.0 2E4KV@1|root,32ZFU@2|Bacteria,2NQ0D@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 SRR21617311_k127_2056137_1 1089548.KI783301_gene405 4.195e-95 323.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3WE5K@539002|Bacillales incertae sedis 91061|Bacilli H Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK SRR21617311_k127_2057337_1 1379698.RBG1_1C00001G0864 8.009e-17 87.0 COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria 2|Bacteria M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744,ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC,OstA,OstA_C SRR21617311_k127_2057337_0 1379698.RBG1_1C00001G0859 1.185e-26 116.0 COG0697@1|root,COG0697@2|Bacteria,2NPMX@2323|unclassified Bacteria 2|Bacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SRR21617311_k127_2060023_0 1379698.RBG1_1C00001G1890 7.753e-93 322.0 COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD SRR21617311_k127_2060023_1 1379698.RBG1_1C00001G1891 9.833e-76 265.0 COG1646@1|root,COG1646@2|Bacteria,2NQW0@2323|unclassified Bacteria 2|Bacteria I PcrB family pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB SRR21617311_k127_2060023_2 932678.THERU_01010 4.993e-45 178.0 COG0279@1|root,COG0279@2|Bacteria,2G410@200783|Aquificae 200783|Aquificae G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 SRR21617311_k127_2063383_2 518766.Rmar_1306 4.397e-44 166.0 COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1FIY2@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Fumarate reductase flavoprotein C-term nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SRR21617311_k127_2063383_0 1379698.RBG1_1C00001G1643 1.691e-53 201.0 COG1663@1|root,COG1663@2|Bacteria,2NPF0@2323|unclassified Bacteria 2|Bacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 LpxK SRR21617311_k127_2063383_1 1379698.RBG1_1C00001G1644 1.253e-44 170.0 COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria 2|Bacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) lpxK - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,LpxK SRR21617311_k127_2073720_0 1379698.RBG1_1C00001G0782 4.318e-141 454.0 COG0065@1|root,COG0065@2|Bacteria,2NP32@2323|unclassified Bacteria 2|Bacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC1 - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR21617311_k127_2073720_1 1379698.RBG1_1C00001G0782 3.242e-36 140.0 COG0065@1|root,COG0065@2|Bacteria,2NP32@2323|unclassified Bacteria 2|Bacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC1 - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR21617311_k127_2073734_0 1379698.RBG1_1C00001G0338 8.667e-214 670.0 COG0046@1|root,COG0046@2|Bacteria,2NNPS@2323|unclassified Bacteria 2|Bacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SRR21617311_k127_2079420_5 1379698.RBG1_1C00001G0164 0.0001222 46.0 COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria 2|Bacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind SRR21617311_k127_2079420_0 1379698.RBG1_1C00001G0715 3.301e-157 506.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SRR21617311_k127_2079420_2 290397.Adeh_2849 3.06e-57 209.0 COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2X5KV@28221|Deltaproteobacteria,2YY40@29|Myxococcales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SRR21617311_k127_2079420_3 1379698.RBG1_1C00001G0716 1.64e-23 107.0 COG2050@1|root,COG2050@2|Bacteria,2NRYC@2323|unclassified Bacteria 2|Bacteria Q Domain of unknown function (DUF4442) - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT SRR21617311_k127_2079420_1 1379698.RBG1_1C00001G0468 9.499e-74 251.0 COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria 2|Bacteria S DinB family yrdA - - - - - - - - - - - DinB SRR21617311_k127_2079420_4 446470.Snas_5727 5.897e-15 76.0 COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4F08K@85014|Glycomycetales 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 SRR21617311_k127_208232_2 1379698.RBG1_1C00001G1360 1.508e-16 81.0 COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria 2|Bacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SRR21617311_k127_208232_0 1379698.RBG1_1C00001G1697 2.678e-165 527.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme metC GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP SRR21617311_k127_208232_1 1379698.RBG1_1C00001G0937 1.655e-35 136.0 COG1635@1|root,COG1635@2|Bacteria,2NR92@2323|unclassified Bacteria 2|Bacteria H Thi4 family thi4 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K03146 ko00730,ko01100,map00730,map01100 - R10685 RC00033,RC03253,RC03254 ko00000,ko00001 - - - FAD_oxidored,Thi4 SRR21617311_k127_2103274_8 945713.IALB_2853 2.71e-25 111.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - - - - - - - - - - OEP SRR21617311_k127_2103274_7 690850.Desaf_1341 1.193e-32 140.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2MCY6@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585,ko:K07799 ko01501,ko01503,ko02020,map01501,map01503,map02020 M00646,M00647,M00648,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1,8.A.1.6 - - HlyD_D23 SRR21617311_k127_2103274_0 1122947.FR7_0621 2.577e-283 902.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes 909932|Negativicutes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran SRR21617311_k127_2103274_2 1379698.RBG1_1C00001G1766 6.749e-136 450.0 COG4365@1|root,COG4365@2|Bacteria,2NP8Q@2323|unclassified Bacteria 2|Bacteria S Bacillithiol biosynthesis BshC bshC - - ko:K22136 - - - - ko00000 - - - BshC SRR21617311_k127_2103274_1 1379698.RBG1_1C00001G1765 9.631e-151 485.0 COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferases group 1 bshA GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2103274_3 1379698.RBG1_1C00001G1764 2.751e-104 343.0 COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria 2|Bacteria S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L SRR21617311_k127_2103274_4 1303518.CCALI_01929 5.424e-64 228.0 COG5424@1|root,COG5424@2|Bacteria 2|Bacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ CP_1111 GO:0005575,GO:0005576 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2,TENA_THI-4 SRR21617311_k127_2103274_6 643648.Slip_1894 1.069e-32 134.0 28JE3@1|root,2Z98B@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - AbiEii SRR21617311_k127_2103274_5 1379698.RBG1_1C00001G1763 5.732e-58 209.0 COG1921@1|root,COG1921@2|Bacteria,2NNT6@2323|unclassified Bacteria 2|Bacteria J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006 Se-cys_synth_N,SelA SRR21617311_k127_2109923_4 945713.IALB_2117 1.642e-08 58.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Peptidase_C10,Phage-tail_3,Prophage_tail,SLH SRR21617311_k127_2109923_0 1379698.RBG1_1C00001G1833 1.071e-178 569.0 COG1379@1|root,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria 2|Bacteria L DNA helicase yqxK - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4178,PHP_C,UvrD-helicase,UvrD_C SRR21617311_k127_2109923_3 1123371.ATXH01000045_gene1871 4.03e-65 233.0 28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2109923_1 1379698.RBG1_1C00001G1510 1.236e-111 375.0 COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria 2|Bacteria S Putative modulator of DNA gyrase tldE2 - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD SRR21617311_k127_2109923_2 1382306.JNIM01000001_gene332 9.17e-104 346.0 COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi 200795|Chloroflexi I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SRR21617311_k127_2120975_1 1235802.C823_04138 3.133e-18 88.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,25WJI@186806|Eubacteriaceae 186801|Clostridia D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf SRR21617311_k127_2120975_2 1460634.JCM19037_193 8.431e-11 72.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 SRR21617311_k127_2120975_0 1379698.RBG1_1C00001G1432 1.07e-104 364.0 COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria 2|Bacteria D Required for chromosome condensation and partitioning smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03529,ko:K19171 - - - - ko00000,ko02048,ko03036 - - - SMC_N,SMC_hinge SRR21617311_k127_2127831_1 1231057.AMGD01000021_gene3247 5.673e-10 69.0 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,26DTC@186818|Planococcaceae 91061|Bacilli S Tetratricopeptide repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 SRR21617311_k127_2127831_0 1499967.BAYZ01000172_gene5776 4.519e-29 124.0 COG1198@1|root,COG1198@2|Bacteria,2NNQ3@2323|unclassified Bacteria 2|Bacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII SRR21617311_k127_2127893_1 1382356.JQMP01000003_gene1858 5.595e-99 329.0 COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia 189775|Thermomicrobia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SRR21617311_k127_2127893_2 518766.Rmar_2216 1.859e-44 167.0 COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1FJES@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SRR21617311_k127_2127893_0 1379698.RBG1_1C00001G1803 7.546e-135 438.0 COG0039@1|root,COG0039@2|Bacteria,2NNY8@2323|unclassified Bacteria 2|Bacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1360 Ldh_1_C,Ldh_1_N SRR21617311_k127_2127893_3 646529.Desaci_0056 1.075e-18 87.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae 186801|Clostridia M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase SRR21617311_k127_2134592_0 416591.Tlet_0400 7.079e-07 57.0 COG1470@1|root,COG1470@2|Bacteria,2GCQ8@200918|Thermotogae 200918|Thermotogae S PFAM PEGA domain - - - - - - - - - - - - DUF4384,PEGA SRR21617311_k127_2136460_2 1379698.RBG1_1C00001G0103 3.797e-105 346.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 SRR21617311_k127_2136460_1 1379698.RBG1_1C00001G0102 3.361e-131 424.0 COG0005@1|root,COG0005@2|Bacteria,2NP5F@2323|unclassified Bacteria 2|Bacteria F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 SRR21617311_k127_2136460_8 1460640.JCM19046_902 1.601e-18 93.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA SRR21617311_k127_2136460_5 1379698.RBG1_1C00001G0100 1.482e-56 205.0 COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria 2|Bacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N SRR21617311_k127_2136460_6 1379698.RBG1_1C00001G0464 2.074e-48 181.0 COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria 2|Bacteria I dolichyl monophosphate biosynthetic process sec59 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SRR21617311_k127_2136460_3 1379698.RBG1_1C00001G0463 1.265e-81 293.0 COG0760@1|root,COG0760@2|Bacteria,2NPFB@2323|unclassified Bacteria 2|Bacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769,ko:K03770,ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 SRR21617311_k127_2136460_4 1379698.RBG1_1C00001G0462 1.985e-75 265.0 COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SRR21617311_k127_2136460_0 1379698.RBG1_1C00001G0603 4.624e-140 452.0 COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SRR21617311_k127_2136460_7 1379698.RBG1_1C00001G0602 1.181e-28 117.0 COG0842@1|root,COG0842@2|Bacteria,2NQCU@2323|unclassified Bacteria 2|Bacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SRR21617311_k127_2136540_0 1191523.MROS_2693 1.743e-255 796.0 COG0459@1|root,COG0459@2|Bacteria 2|Bacteria O protein refolding groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SRR21617311_k127_2136540_5 1379698.RBG1_1C00001G0288 4.637e-38 145.0 COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 SRR21617311_k127_2136540_7 67332.FM21_06650 2.183e-14 82.0 COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria 201174|Actinobacteria Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 SRR21617311_k127_2136540_2 1379698.RBG1_1C00001G0995 1.069e-114 400.0 COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria 2|Bacteria E Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO SRR21617311_k127_2136540_6 1379698.RBG1_1C00001G0552 1.191e-21 98.0 COG1544@1|root,COG1544@2|Bacteria 2|Bacteria J regulation of translation hpf GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808,ko:K05809 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE SRR21617311_k127_2136540_1 1379698.RBG1_1C00001G0553 7.544e-143 460.0 COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria 2|Bacteria T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N SRR21617311_k127_2136540_3 1379698.RBG1_1C00001G0556 4.334e-76 265.0 COG1463@1|root,COG1463@2|Bacteria,2NPXB@2323|unclassified Bacteria 2|Bacteria Q MlaD protein ttg2C - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SRR21617311_k127_2136540_4 255470.cbdbA1071 7.107e-66 241.0 COG0726@1|root,COG1215@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,2G76U@200795|Chloroflexi,34CUR@301297|Dehalococcoidia 301297|Dehalococcoidia GM Polysaccharide deacetylase - - - - - - - - - - - - Glycos_transf_2,Polysacc_deac_1 SRR21617311_k127_213674_0 1379698.RBG1_1C00001G1099 5.076e-50 188.0 COG1512@1|root,COG1512@2|Bacteria,2NQ0J@2323|unclassified Bacteria 2|Bacteria S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase SRR21617311_k127_213674_1 909663.KI867150_gene67 6.308e-06 52.0 COG3937@1|root,COG3937@2|Bacteria,1Q1WC@1224|Proteobacteria,437II@68525|delta/epsilon subdivisions,2WYKH@28221|Deltaproteobacteria,2MQQX@213462|Syntrophobacterales 28221|Deltaproteobacteria S granule-associated protein - - - - - - - - - - - - - SRR21617311_k127_2137198_2 1379698.RBG1_1C00001G0435 6.081e-10 67.0 COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria 2|Bacteria M methyltransferase greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N,SprA_N SRR21617311_k127_2137198_0 1379698.RBG1_1C00001G0434 4.4e-84 289.0 COG0812@1|root,COG0812@2|Bacteria,2NPHQ@2323|unclassified Bacteria 2|Bacteria M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C SRR21617311_k127_2137198_1 765420.OSCT_0965 6.485e-29 133.0 28M0D@1|root,2ZAFE@2|Bacteria,2G9HQ@200795|Chloroflexi 200795|Chloroflexi S Putative ATP-binding cassette - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran_2 SRR21617311_k127_2152714_1 28072.Nos7524_4598 0.0001553 53.0 COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,1HJJ5@1161|Nostocales 1117|Cyanobacteria S ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane_2 SRR21617311_k127_2152714_0 1123508.JH636441_gene3158 7.724e-41 156.0 COG1131@1|root,COG1131@2|Bacteria,2IZ31@203682|Planctomycetes 203682|Planctomycetes V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_2158156_1 1410618.JNKI01000012_gene624 8.17e-08 54.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4H2FF@909932|Negativicutes 909932|Negativicutes G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 SRR21617311_k127_2158156_0 1379698.RBG1_1C00001G0069 4.191e-54 199.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria 2|Bacteria O Subtilase family - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CHU_C,FlgD_ig,PKD,Peptidase_S8 SRR21617311_k127_2166987_1 1453498.LG45_01660 3.09e-11 68.0 COG4675@1|root,COG5295@1|root,COG4675@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia,2NUBX@237|Flavobacterium 976|Bacteroidetes UW arginyl-trna synthetase - - - - - - - - - - - - - SRR21617311_k127_2166987_0 1379698.RBG1_1C00001G1235 1.281e-41 171.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CarbopepD_reg_2 SRR21617311_k127_2175106_0 1121430.JMLG01000013_gene1898 1.377e-78 271.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,26109@186807|Peptococcaceae 186801|Clostridia I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB SRR21617311_k127_2175106_1 1379698.RBG1_1C00001G0841 5.523e-44 168.0 COG0586@1|root,COG0586@2|Bacteria,2NREP@2323|unclassified Bacteria 2|Bacteria S SNARE associated Golgi protein yngC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc SRR21617311_k127_2178777_4 1379698.RBG1_1C00001G0387 2.478e-36 142.0 COG2001@1|root,COG2001@2|Bacteria,2NPTY@2323|unclassified Bacteria 2|Bacteria K MraZ protein, putative antitoxin-like mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ SRR21617311_k127_2178777_3 1120973.AQXL01000130_gene1217 9.261e-83 285.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,2797Y@186823|Alicyclobacillaceae 91061|Bacilli M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 SRR21617311_k127_2178777_1 1379698.RBG1_1C00001G0390 2.215e-136 466.0 COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding Protein dimerisation domain ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PASTA,PBP_dimer,Transpeptidase SRR21617311_k127_2178777_0 1379698.RBG1_1C00001G0391 6.132e-140 467.0 COG0769@1|root,COG0769@2|Bacteria,2NNZM@2323|unclassified Bacteria 2|Bacteria M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 - R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR21617311_k127_2178777_2 1379698.RBG1_1C00001G0392 7.341e-108 364.0 COG0770@1|root,COG0770@2|Bacteria,2NP4Q@2323|unclassified Bacteria 2|Bacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR21617311_k127_2183958_1 1379698.RBG1_1C00001G0979 7.246e-108 355.0 COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SRR21617311_k127_2183958_2 1379698.RBG1_1C00001G0978 7.234e-79 271.0 COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE SRR21617311_k127_2183958_0 1379698.RBG1_1C00001G0977 8.69e-169 541.0 COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C SRR21617311_k127_2183958_3 1379698.RBG1_1C00001G0976 3.598e-35 136.0 COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria 2|Bacteria L Uracil DNA glycosylase superfamily ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SRR21617311_k127_2184921_3 1379698.RBG1_1C00001G0883 1.173e-108 358.0 COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria 2|Bacteria G binding-protein-dependent transport systems inner membrane component - - - ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 SRR21617311_k127_2184921_2 1379698.RBG1_1C00001G0884 1.469e-127 420.0 COG2182@1|root,COG2182@2|Bacteria 2|Bacteria G maltose binding - - - ko:K02027,ko:K17329 ko02010,map02010 M00207,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.33 - - SBP_bac_1,SBP_bac_8 SRR21617311_k127_2184921_5 671143.DAMO_0348 5.464e-68 241.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2184921_9 247490.KSU1_B0649 1.428e-46 175.0 29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SRR21617311_k127_2184921_8 671143.DAMO_0350 1.744e-54 201.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2184921_10 237368.SCABRO_03012 6.16e-45 171.0 2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SRR21617311_k127_2184921_6 1379698.RBG1_1C00001G0886 7.825e-60 222.0 COG1686@1|root,COG1686@2|Bacteria,2NPJT@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S11 family pbpG GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 ko:K01286,ko:K07258,ko:K07262 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iECO103_1326.ECO103_2610,iYL1228.KPN_02573 Peptidase_S11 SRR21617311_k127_2184921_7 1379698.RBG1_1C00001G0422 1.857e-57 207.0 COG0755@1|root,COG0755@2|Bacteria,2NPGT@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm SRR21617311_k127_2184921_11 1379698.RBG1_1C00001G0421 4.671e-40 151.0 COG2332@1|root,COG2332@2|Bacteria,2NQ2A@2323|unclassified Bacteria 2|Bacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE SRR21617311_k127_2184921_0 1379698.RBG1_1C00001G1882 5.853e-161 534.0 COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm SRR21617311_k127_2184921_4 1379698.RBG1_1C00001G0157 3.9e-106 359.0 COG0642@1|root,COG2205@2|Bacteria 1379698.RBG1_1C00001G0157|- T PhoQ Sensor - - - - - - - - - - - - - SRR21617311_k127_2184921_1 1379698.RBG1_1C00001G0158 1.602e-145 480.0 COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria 2|Bacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Response_reg SRR21617311_k127_2186156_0 1379698.RBG1_1C00001G1470 3.388e-127 415.0 COG0439@1|root,COG0439@2|Bacteria,2NNKD@2323|unclassified Bacteria 2|Bacteria I carboxylase, biotin carboxylase pccA - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 ko:K01961,ko:K01968,ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00036,M00082,M00376,M00741 R00742,R01859,R04138,R04385 RC00040,RC00097,RC00253,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 SRR21617311_k127_2186156_1 1379698.RBG1_1C00001G1253 2.328e-44 166.0 COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria 2|Bacteria I COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR21617311_k127_2188968_0 29581.BW37_05166 2.667e-42 157.0 2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2VXKG@28216|Betaproteobacteria,477HG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 SRR21617311_k127_2188968_1 404380.Gbem_2520 4.447e-28 114.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales 28221|Deltaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 SRR21617311_k127_2194133_0 1379698.RBG1_1C00001G1511 3.593e-208 657.0 COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria 2|Bacteria S Putative modulator of DNA gyrase tldD2 - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SRR21617311_k127_2194133_1 1379698.RBG1_1C00001G1510 8.033e-175 560.0 COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria 2|Bacteria S Putative modulator of DNA gyrase tldE2 - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD SRR21617311_k127_2194133_2 880073.Calab_0513 6.884e-63 233.0 2C3GN@1|root,31EWU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2197764_3 635013.TherJR_1870 3.889e-71 253.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae 186801|Clostridia J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind SRR21617311_k127_2197764_6 1379698.RBG1_1C00001G1122 4.747e-25 108.0 COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria 2|Bacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA SRR21617311_k127_2197764_0 1379698.RBG1_1C00001G1123 1.574e-225 709.0 COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria 2|Bacteria S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 SRR21617311_k127_2197764_4 1216007.AOPM01000075_gene1244 9.048e-42 162.0 COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,2Q0M8@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1287) - - - ko:K09974 - - - - ko00000 - - - DUF1287 SRR21617311_k127_2197764_1 373994.Riv7116_0186 2.148e-138 458.0 COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1HII6@1161|Nostocales 1117|Cyanobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB SRR21617311_k127_2197764_5 1382356.JQMP01000004_gene540 6.798e-33 132.0 COG3288@1|root,COG3288@2|Bacteria,2GBAD@200795|Chloroflexi,27YI1@189775|Thermomicrobia 189775|Thermomicrobia C 4TM region of pyridine nucleotide transhydrogenase, mitoch - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM SRR21617311_k127_2197764_2 118163.Ple7327_1113 9.168e-77 265.0 COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3VI0U@52604|Pleurocapsales 1117|Cyanobacteria C PFAM Alanine dehydrogenase PNT, C-terminal domain pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N SRR21617311_k127_2204940_0 459349.CLOAM1546 1.169e-77 290.0 COG0457@1|root,COG3604@1|root,COG0457@2|Bacteria,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding nifA - - ko:K02584,ko:K11914 ko02020,map02020 - - - ko00000,ko00001,ko02044,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat SRR21617311_k127_2210194_0 269799.Gmet_2497 1.134e-102 352.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales 28221|Deltaproteobacteria H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657,ko:K13503 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SRR21617311_k127_2210194_1 563192.HMPREF0179_02499 4.49e-58 209.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMIV@28221|Deltaproteobacteria,2MGEF@213115|Desulfovibrionales 28221|Deltaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase SRR21617311_k127_2229074_0 1140.Synpcc7942_1337 1.445e-51 199.0 COG2273@1|root,COG2931@1|root,COG2273@2|Bacteria,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus 1117|Cyanobacteria Q Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Calx-beta,FG-GAP SRR21617311_k127_2229074_1 1379698.RBG1_1C00001G1485 5.986e-21 93.0 COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S21 rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 SRR21617311_k127_2239286_2 243231.GSU0016 4.154e-06 56.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03769,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 SRR21617311_k127_2239286_1 1379698.RBG1_1C00001G1776 3.786e-63 229.0 COG3088@1|root,COG3088@2|Bacteria,2NS4V@2323|unclassified Bacteria 2|Bacteria O subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018 - - R05712 RC00176 ko00000,ko02000 9.B.14.1 - - CcmH SRR21617311_k127_2239286_0 1379698.RBG1_1C00001G1775 1.05e-117 387.0 COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria 2|Bacteria NU von Willebrand factor (vWF) type A domain batA - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA SRR21617311_k127_2241923_11 1499967.BAYZ01000147_gene720 1.418e-05 50.0 COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria 2|Bacteria M rod shape-determining protein MreD mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD SRR21617311_k127_2241923_8 1379698.RBG1_1C00001G1001 2.863e-42 166.0 COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria 2|Bacteria M Cell shape-determining protein MreC mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC SRR21617311_k127_2241923_6 1379698.RBG1_1C00001G1000 1.616e-61 215.0 COG1762@1|root,COG1762@2|Bacteria,2NPVC@2323|unclassified Bacteria 2|Bacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 SRR21617311_k127_2241923_10 648996.Theam_1326 9.124e-15 75.0 COG2835@1|root,COG2835@2|Bacteria,2G4D1@200783|Aquificae 200783|Aquificae S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p SRR21617311_k127_2241923_0 1379698.RBG1_1C00001G0998 4.406e-139 449.0 COG0825@1|root,COG0825@2|Bacteria,2NNVQ@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN678.accA ACCA SRR21617311_k127_2241923_5 1009370.ALO_09919 7.105e-69 247.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H2U9@909932|Negativicutes 909932|Negativicutes M Glycosyltransferase, group 4 family tagO - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 SRR21617311_k127_2241923_7 1122918.KB907246_gene1454 1.659e-54 203.0 COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,26TD7@186822|Paenibacillaceae 91061|Bacilli S glycosyl transferase family 2 galnac-T15 - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2 SRR21617311_k127_2241923_1 1379698.RBG1_1C00001G0996 1.461e-116 380.0 COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase like family 2 dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SRR21617311_k127_2241923_9 42256.RradSPS_0752 1.083e-23 111.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027,ko:K20468 - - - - ko00000,ko02000 4.D.2,4.D.2.4.1 - - LPG_synthase_TM SRR21617311_k127_2241923_2 1379698.RBG1_1C00001G1315 1.102e-100 340.0 COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase like family 2 arnC - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SRR21617311_k127_2241923_4 1379698.RBG1_1C00001G1090 8.357e-87 299.0 COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria 2|Bacteria S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 SRR21617311_k127_2241923_3 1125863.JAFN01000001_gene3034 1.276e-93 328.0 COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria 28221|Deltaproteobacteria T metal-dependent phosphohydrolase HD region - - - - - - - - - - - - GAF_2,GAF_3,HD,Response_reg SRR21617311_k127_2244533_0 1379698.RBG1_1C00001G1789 2.761e-279 894.0 COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria 2|Bacteria S Propeptide_C25 porU - - - - - - - - - - - Peptidase_C25 SRR21617311_k127_2244533_1 1379698.RBG1_1C00001G1788 3.748e-227 731.0 COG2067@1|root,COG3292@1|root,COG2067@2|Bacteria,COG3292@2|Bacteria,2NPQZ@2323|unclassified Bacteria 2|Bacteria I Two component regulator propeller - - - - - - - - - - - - CHB_HEX_C_1,Reg_prop,Reprolysin_5,VCBS SRR21617311_k127_2244533_2 1379698.RBG1_1C00001G1787 1.561e-42 164.0 COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - DUF1863,PQQ_2 SRR21617311_k127_2246925_0 1379698.RBG1_1C00001G0449 2.62e-140 456.0 COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria 2|Bacteria M ABC-type transport system involved in lipoprotein release permease component lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 - - FtsX,MacB_PCD SRR21617311_k127_2246925_1 880073.Calab_1380 3.009e-118 386.0 COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DUF4332,tRNA-synt_2,tRNA_anti-codon SRR21617311_k127_2250660_0 945713.IALB_3000 8.706e-66 227.0 COG5405@1|root,COG5405@2|Bacteria 2|Bacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome SRR21617311_k127_2250660_2 1121324.CLIT_11c02670 1.089e-40 154.0 2E74N@1|root,331P2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2250660_3 1122185.N792_08685 1.075e-34 140.0 COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria,1XC40@135614|Xanthomonadales 135614|Xanthomonadales S Cysteine dioxygenase type I - - - - - - - - - - - - CDO_I SRR21617311_k127_2250660_1 661478.OP10G_1618 2.516e-47 173.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase SRR21617311_k127_2252104_3 1191523.MROS_0259 2.357e-05 53.0 COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria 2|Bacteria L chaperone-mediated protein folding - - 2.7.8.12 ko:K09809,ko:K20543 - - - - ko00000,ko01000,ko02000 1.B.55.3 - - BCSC_C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 SRR21617311_k127_2252104_1 1379698.RBG1_1C00001G0415 1.49e-146 477.0 COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 SRR21617311_k127_2252104_0 1379698.RBG1_1C00001G0414 0.0 1075.0 COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria 2|Bacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iLJ478.TM1817 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 SRR21617311_k127_2252104_2 868864.Dester_1329 1.877e-71 250.0 COG1694@1|root,COG3956@2|Bacteria,2G3T8@200783|Aquificae 200783|Aquificae S TIGRFAM MazG family protein mazG - - ko:K02499 - - - - ko00000,ko03036 - - - MazG SRR21617311_k127_2252104_4 83406.HDN1F_23590 0.000695 46.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S479@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q SMART Integrin alpha beta-propellor repeat protein - - 3.1.4.50 ko:K01127 ko00563,map00563 - R06623 - ko00000,ko00001,ko01000 - - - FG-GAP SRR21617311_k127_225597_3 234267.Acid_0827 1.042e-44 173.0 COG1108@1|root,COG1108@2|Bacteria,3Y93X@57723|Acidobacteria 57723|Acidobacteria P ABC 3 transport family - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 SRR21617311_k127_225597_4 671143.DAMO_1981 1.264e-26 114.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA SRR21617311_k127_225597_2 234267.Acid_0826 1.776e-48 179.0 COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria 57723|Acidobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA SRR21617311_k127_225597_0 671143.DAMO_1980 6.374e-107 359.0 COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria 2|Bacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - SRR21617311_k127_225597_1 555779.Dthio_PD1455 1.775e-70 244.0 2B1WT@1|root,31UCY@2|Bacteria,1NK5F@1224|Proteobacteria,43055@68525|delta/epsilon subdivisions,2WV87@28221|Deltaproteobacteria,2MEXM@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2265350_0 671143.DAMO_2785 4.873e-84 288.0 COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria 2|Bacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 SRR21617311_k127_2265350_1 439481.Aboo_1349 1.926e-47 173.0 COG4275@1|root,arCOG10427@2157|Archaea,2XXPQ@28890|Euryarchaeota 28890|Euryarchaeota S Chromate resistance - - - - - - - - - - - - Chrome_Resist SRR21617311_k127_2265350_2 1379698.RBG1_1C00001G0536 3.387e-34 134.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SRR21617311_k127_2268497_0 1379698.RBG1_1C00001G0777 0.0 1622.0 COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria 2|Bacteria P Prokaryotic cytochrome b561 cbcY - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese SRR21617311_k127_2268497_1 1379698.RBG1_1C00001G0778 2.153e-18 84.0 COG3005@1|root,COG3005@2|Bacteria,2NQ9M@2323|unclassified Bacteria 2|Bacteria C NapC/NirT cytochrome c family, N-terminal region - - - - - - - - - - - - Cytochrom_NNT,Cytochrom_c3_2 SRR21617311_k127_226867_2 1379698.RBG1_1C00001G0976 9.69e-77 263.0 COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria 2|Bacteria L Uracil DNA glycosylase superfamily ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SRR21617311_k127_226867_1 401526.TcarDRAFT_2084 1.879e-118 394.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes 909932|Negativicutes H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein SRR21617311_k127_226867_0 1379698.RBG1_1C00001G0972 1.216e-122 404.0 COG0138@1|root,COG0138@2|Bacteria,2NNQ2@2323|unclassified Bacteria 2|Bacteria F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS SRR21617311_k127_2270959_4 1237149.C900_05654 7.309e-59 206.0 2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,47RDY@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 SRR21617311_k127_2270959_2 1379698.RBG1_1C00001G0488 7.042e-74 279.0 COG4447@1|root,COG4447@2|Bacteria,2NRAH@2323|unclassified Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CHU_C,Cu_amine_oxidN1,F5_F8_type_C SRR21617311_k127_2270959_3 1379698.RBG1_1C00001G0489 2.115e-65 237.0 COG2067@1|root,COG2067@2|Bacteria,2NRFG@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SRR21617311_k127_2270959_5 1379698.RBG1_1C00001G0490 2.407e-48 184.0 COG2067@1|root,COG2067@2|Bacteria,2NR8A@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SRR21617311_k127_2270959_6 397278.JOJN01000002_gene86 6.902e-15 87.0 COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria 201174|Actinobacteria D Ribonuclease bn - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB SRR21617311_k127_2270959_1 1379698.RBG1_1C00001G0492 5.383e-103 345.0 COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria 2|Bacteria S AI-2E family transporter tqsA - - - - - - - - - - - AI-2E_transport SRR21617311_k127_2270959_0 1379698.RBG1_1C00001G0494 6.408e-294 915.0 COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria 2|Bacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 SRR21617311_k127_2270959_7 545243.BAEV01000034_gene1712 5.574e-09 58.0 COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia,36W87@31979|Clostridiaceae 186801|Clostridia E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR21617311_k127_2271539_1 401526.TcarDRAFT_0216 7.883e-86 292.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,4H2B6@909932|Negativicutes 909932|Negativicutes J Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - LYTB,S1 SRR21617311_k127_2271539_6 1379698.RBG1_1C00001G1226 4.994e-44 171.0 COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria 2|Bacteria I Phosphate acyltransferases cmk - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SRR21617311_k127_2271539_3 1173028.ANKO01000106_gene365 5.465e-56 203.0 COG0283@1|root,COG0414@1|root,COG0283@2|Bacteria,COG0414@2|Bacteria,1G1BX@1117|Cyanobacteria,1H7SQ@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC/cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 ko:K13799 ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110 M00052,M00119 R00158,R00512,R01665,R02473 RC00002,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin,Pantoate_ligase SRR21617311_k127_2271539_4 1379698.RBG1_1C00001G1228 2.825e-52 192.0 COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria 2|Bacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB SRR21617311_k127_2271539_5 1379698.RBG1_1C00001G1229 5.659e-52 196.0 COG1354@1|root,COG1354@2|Bacteria,2NPM8@2323|unclassified Bacteria 2|Bacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA SRR21617311_k127_2271539_0 1379698.RBG1_1C00001G1230 1.775e-157 505.0 COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class I (W and Y) trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b SRR21617311_k127_2271539_2 1379698.RBG1_1C00001G1232 1.688e-80 271.0 COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria 2|Bacteria L HNH endonuclease mcrA - - - - - - - - - - - HNH,HNH_4,HNH_5 SRR21617311_k127_228334_2 880073.Calab_3408 1.65e-41 160.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Cytochrome_C554,DUF11,SLH SRR21617311_k127_228334_1 1379698.RBG1_1C00001G0781 1.909e-52 190.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain petA - 1.10.2.2,1.10.9.1 ko:K00411,ko:K02636,ko:K03886 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - iAF987.Gmet_1922 CytB6-F_Fe-S,Rieske,UCR_Fe-S_N SRR21617311_k127_228334_0 1379698.RBG1_1C00001G0780 1.838e-53 190.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B SRR21617311_k127_2315812_1 1207063.P24_18764 1.273e-10 68.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2JPYC@204441|Rhodospirillales 204441|Rhodospirillales O COG0457 FOG TPR repeat - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 SRR21617311_k127_2315812_0 1379698.RBG1_1C00001G1817 2.08e-59 225.0 COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria 2|Bacteria E aminopeptidase N - - - - - - - - - - - - CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B SRR21617311_k127_2320220_1 926692.AZYG01000019_gene272 6.566e-56 207.0 COG0834@1|root,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,25C2V@186801|Clostridia,3WBAA@53433|Halanaerobiales 186801|Clostridia ET Bacterial periplasmic substrate-binding proteins glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 SRR21617311_k127_2320220_3 1379698.RBG1_1C00001G1696 2.154e-55 199.0 COG0590@1|root,COG0590@2|Bacteria,2NPM7@2323|unclassified Bacteria 2|Bacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam SRR21617311_k127_2320220_2 913325.N799_13835 2.114e-55 200.0 COG4430@1|root,COG4430@2|Bacteria,1N8ME@1224|Proteobacteria,1T0U8@1236|Gammaproteobacteria,1XD1S@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905,OmdA SRR21617311_k127_2320220_0 265729.GS18_0219295 2.338e-63 222.0 COG3832@1|root,COG3832@2|Bacteria,1VW43@1239|Firmicutes 1239|Firmicutes J glyoxalase III activity - - - - - - - - - - - - - SRR21617311_k127_2320220_4 1379698.RBG1_1C00001G0789 3.052e-53 188.0 COG2081@1|root,COG2081@2|Bacteria,2NPCB@2323|unclassified Bacteria 2|Bacteria S HI0933-like protein yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like SRR21617311_k127_2320220_6 1379698.RBG1_1C00001G0789 1.942e-08 56.0 COG2081@1|root,COG2081@2|Bacteria,2NPCB@2323|unclassified Bacteria 2|Bacteria S HI0933-like protein yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like SRR21617311_k127_2324971_1 1379698.RBG1_1C00001G0311 4.04e-38 147.0 COG0799@1|root,COG0799@2|Bacteria,2NPYI@2323|unclassified Bacteria 2|Bacteria S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 - - - RsfS SRR21617311_k127_2324971_0 1379698.RBG1_1C00001G0312 6.365e-226 708.0 COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria 2|Bacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind SRR21617311_k127_2328166_4 404380.Gbem_3422 1.156e-80 279.0 COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,42T6J@68525|delta/epsilon subdivisions,2WPVY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase SRR21617311_k127_2328166_2 944479.JQLX01000015_gene28 4.813e-87 298.0 COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2M6IZ@213113|Desulfurellales 28221|Deltaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE - 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase SRR21617311_k127_2328166_3 1379698.RBG1_1C00001G0056 9.454e-82 277.0 COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria 2|Bacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase SRR21617311_k127_2328166_6 1379698.RBG1_1C00001G0055 2.95e-70 249.0 COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria 2|Bacteria I PAP2 superfamily - - - - - - - - - - - - PAP2_3 SRR21617311_k127_2328166_7 1379698.RBG1_1C00001G1006 2.242e-63 230.0 COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria 2|Bacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT SRR21617311_k127_2328166_9 42256.RradSPS_0259 3.328e-32 134.0 COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria 84995|Rubrobacteria I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SRR21617311_k127_2328166_0 1379698.RBG1_1C00001G1837 1.969e-214 671.0 COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria 2|Bacteria I Myo-inositol-1-phosphate synthase ino1 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth SRR21617311_k127_2328166_11 1229172.JQFA01000002_gene2339 3.007e-14 74.0 2C7RX@1|root,32RJP@2|Bacteria,1G859@1117|Cyanobacteria,1HC7Z@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2328166_13 102129.Lepto7375DRAFT_7165 7.864e-10 63.0 2C7RX@1|root,32RJP@2|Bacteria,1G859@1117|Cyanobacteria,1HC7Z@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2328166_12 313612.L8106_13450 4.533e-10 64.0 2C4F2@1|root,331RG@2|Bacteria,1G9S1@1117|Cyanobacteria,1HDB3@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2328166_8 264732.Moth_0042 3.163e-55 201.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,42GBY@68295|Thermoanaerobacterales 186801|Clostridia F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin SRR21617311_k127_2328166_1 1379698.RBG1_1C00001G1839 5.139e-142 470.0 COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 SRR21617311_k127_2328166_10 1379698.RBG1_1C00001G1840 2.598e-14 78.0 COG0730@1|root,COG0730@2|Bacteria,2NQ5J@2323|unclassified Bacteria 2|Bacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SRR21617311_k127_2329677_1 1379698.RBG1_1C00001G0581 8.366e-30 134.0 COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - - - - - - - - - - - ASH,Cohesin,FlgD_ig,Peptidase_S74 SRR21617311_k127_2329677_0 1379698.RBG1_1C00001G1194 7.728e-30 126.0 COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - 3.2.1.91 ko:K14194,ko:K19668 ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CHU_C,DUF11,FlgD_ig,PKD,SdrD_B SRR21617311_k127_2329928_3 706587.Desti_2948 7.075e-40 158.0 COG0069@1|root,COG0069@2|Bacteria 2|Bacteria E glutamate synthase activity - - - - - - - - - - - - Fer4,Glu_synthase SRR21617311_k127_2329928_2 7739.XP_002595227.1 1.575e-51 196.0 COG1607@1|root,KOG2763@2759|Eukaryota,38EDX@33154|Opisthokonta,3B9Y2@33208|Metazoa,3CS4E@33213|Bilateria,488ZX@7711|Chordata 33208|Metazoa I acetyl-CoA hydrolase activity ACOT9 GO:0003674,GO:0003824,GO:0003986,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0031974,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - ko:K17361 - - - - ko00000,ko01000,ko01004 - - - - SRR21617311_k127_2329928_5 565033.GACE_0073 1.607e-09 62.0 COG1145@1|root,arCOG00958@2157|Archaea,2Y00E@28890|Euryarchaeota,246H0@183980|Archaeoglobi 183980|Archaeoglobi C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4 SRR21617311_k127_2329928_0 589924.Ferp_0366 5.8e-94 322.0 COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,245QU@183980|Archaeoglobi 183980|Archaeoglobi C Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - 1.3.1.101,1.3.7.11 ko:K17830 ko00564,map00564 - R10325,R10326,R10331 RC03134 ko00000,ko00001,ko01000 - - - FAD_binding_3 SRR21617311_k127_2329928_1 1121481.AUAS01000006_gene877 3.175e-54 211.0 COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia 976|Bacteroidetes Q SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - CHU_C,FG-GAP,HYR,VCBS SRR21617311_k127_2329928_4 316067.Geob_2631 4.781e-21 98.0 COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43UWZ@69541|Desulfuromonadales 28221|Deltaproteobacteria K transcriptional regulator, Rrf2 family - - - - - - - - - - - - Rrf2 SRR21617311_k127_2330507_0 1379698.RBG1_1C00001G0881 8.732e-174 564.0 COG0860@1|root,COG0860@2|Bacteria,2NQ79@2323|unclassified Bacteria 2|Bacteria M Ami_3 amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,GHL10,SpoIID SRR21617311_k127_2330507_1 1379698.RBG1_1C00001G0882 1.532e-94 317.0 COG0395@1|root,COG0395@2|Bacteria,2NPFW@2323|unclassified Bacteria 2|Bacteria U binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SRR21617311_k127_2349988_1 592015.HMPREF1705_00603 2.5e-77 266.0 COG0177@1|root,COG0177@2|Bacteria 2|Bacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K07457,ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD SRR21617311_k127_2349988_2 309800.C498_18308 4.57e-05 55.0 COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,23SJ7@183963|Halobacteria 183963|Halobacteria L DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks hel308 - - ko:K03726 - - - - ko00000,ko01000 - - - DEAD,HHH_5,Helicase_C SRR21617311_k127_235584_1 589924.Ferp_1774 4.593e-15 84.0 COG0388@1|root,arCOG00062@2157|Archaea,2XVR0@28890|Euryarchaeota,245Z8@183980|Archaeoglobi 183980|Archaeoglobi S Carbon-nitrogen hydrolase - - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase SRR21617311_k127_235584_0 290512.Paes_0269 7.578e-33 132.0 COG0744@1|root,COG0744@2|Bacteria,1FDQX@1090|Chlorobi 1090|Chlorobi M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly SRR21617311_k127_2356239_2 1379698.RBG1_1C00001G0153 6.875e-17 82.0 COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N SRR21617311_k127_2356239_0 1379698.RBG1_1C00001G0152 6.907e-89 301.0 COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt SRR21617311_k127_2356239_1 1379698.RBG1_1C00001G0150 3.921e-59 207.0 COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N SRR21617311_k127_2357044_2 1379698.RBG1_1C00001G0970 9.55e-10 61.0 COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PMT_2 SRR21617311_k127_2357044_0 1379698.RBG1_1C00001G0971 1.485e-115 384.0 COG0152@1|root,COG0152@2|Bacteria,2NP0V@2323|unclassified Bacteria 2|Bacteria F SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 - - - SAICAR_synt SRR21617311_k127_2357044_1 671143.DAMO_1629 9.735e-34 136.0 COG0138@1|root,COG0138@2|Bacteria,2NNQ2@2323|unclassified Bacteria 2|Bacteria F Bifunctional purine biosynthesis protein PurH purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS SRR21617311_k127_236457_2 397278.JOJN01000019_gene2333 7.913e-09 68.0 COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria 201174|Actinobacteria Q PA14 domain - - - - - - - - - - - - Malectin,PA14 SRR21617311_k127_236457_0 1379698.RBG1_1C00001G1092 1.402e-225 720.0 COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria 2|Bacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.4.17.18,3.4.17.22 ko:K05996,ko:K07752 - - - - ko00000,ko01000,ko01002 - - - F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3 SRR21617311_k127_236457_1 1379698.RBG1_1C00001G1199 5.427e-51 192.0 COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria 2|Bacteria T Signal transduction histidine kinase, nitrogen specific, NtrB - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9 SRR21617311_k127_2373051_0 671143.DAMO_1500 5.892e-146 477.0 COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria 2|Bacteria C pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase SRR21617311_k127_2373051_1 1379698.RBG1_1C00001G1725 6.623e-13 70.0 COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria 2|Bacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrD - - ko:K03296,ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran SRR21617311_k127_239345_1 397945.Aave_2829 0.0005538 45.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,4AAI2@80864|Comamonadaceae 28216|Betaproteobacteria G glucose sorbosone yliI - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH SRR21617311_k127_239345_0 1379698.RBG1_1C00001G0287 8.144e-151 492.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 SRR21617311_k127_239721_0 1379698.RBG1_1C00001G1762 6.92e-180 582.0 COG3276@1|root,COG3276@2|Bacteria,2NNQU@2323|unclassified Bacteria 2|Bacteria J Elongation factor SelB, winged helix selB GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 SRR21617311_k127_239721_1 1379698.RBG1_1C00001G1763 1.504e-60 216.0 COG1921@1|root,COG1921@2|Bacteria,2NNT6@2323|unclassified Bacteria 2|Bacteria J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006 Se-cys_synth_N,SelA SRR21617311_k127_2397978_2 1379698.RBG1_1C00001G1716 6.748e-15 76.0 COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria 2|Bacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SRR21617311_k127_2397978_1 234267.Acid_2818 5.508e-21 102.0 2EPXQ@1|root,33HI8@2|Bacteria,3Y5ZD@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2397978_0 867903.ThesuDRAFT_00368 6.022e-138 455.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,3WCEP@538999|Clostridiales incertae sedis 186801|Clostridia E Aromatic amino acid lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic SRR21617311_k127_2398362_0 1308866.J416_02034 7.552e-75 266.0 COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,4HKSK@91061|Bacilli 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2398362_1 1273538.G159_16625 1.275e-71 249.0 COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,26F6V@186818|Planococcaceae 91061|Bacilli M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB SRR21617311_k127_2398362_4 522306.CAP2UW1_0479 3.483e-05 56.0 COG4675@1|root,COG4675@2|Bacteria,1NHDM@1224|Proteobacteria,2W6BN@28216|Betaproteobacteria 28216|Betaproteobacteria S tail collar domain protein - - - - - - - - - - - - - SRR21617311_k127_2398362_3 1237149.C900_01790 1.213e-15 90.0 COG0729@1|root,COG2911@1|root,COG0729@2|Bacteria,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - Bac_surface_Ag,Haemagg_act,Peptidase_S74 SRR21617311_k127_2398362_2 526227.Mesil_3344 4.73e-24 117.0 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein yeeJ - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF5122,Peptidase_S74,YadA_head,YadA_stalk SRR21617311_k127_240024_1 1379698.RBG1_1C00001G1481 3.898e-131 439.0 COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria 2|Bacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 SRR21617311_k127_240024_0 401526.TcarDRAFT_1802 2.241e-152 510.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H2Z9@909932|Negativicutes 909932|Negativicutes L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr SRR21617311_k127_240024_2 1379698.RBG1_1C00001G0321 8.419e-33 141.0 COG1629@1|root,COG4771@2|Bacteria,2NRBR@2323|unclassified Bacteria 2|Bacteria P TonB dependent receptor oprC - - ko:K02014,ko:K16087 - - - - ko00000,ko02000 1.B.14,1.B.14.2 - - Plug,TonB_dep_Rec SRR21617311_k127_2409052_0 1379698.RBG1_1C00001G1633 2.032e-188 595.0 COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSB619.SA_RS07880 HGTP_anticodon,tRNA-synt_2b SRR21617311_k127_2409052_1 1379698.RBG1_1C00001G1634 9.037e-43 168.0 COG1381@1|root,COG1381@2|Bacteria,2NPV3@2323|unclassified Bacteria 2|Bacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N SRR21617311_k127_2409052_3 56780.SYN_01733 1.288e-05 48.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2MQ9W@213462|Syntrophobacterales 28221|Deltaproteobacteria F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SRR21617311_k127_2410081_1 1379698.RBG1_1C00001G1707 1.376e-95 317.0 COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria 2|Bacteria P TrkA-C domain trkA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N SRR21617311_k127_2410081_3 1382356.JQMP01000004_gene330 1.612e-36 144.0 COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,27YE9@189775|Thermomicrobia 189775|Thermomicrobia C Putative NAD(P)-binding - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_N SRR21617311_k127_2410081_2 1379698.RBG1_1C00001G1709 5.151e-70 242.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - - - - - - - - - - Usp SRR21617311_k127_2410081_0 264732.Moth_1345 7.201e-240 751.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,42HW4@68295|Thermoanaerobacterales 1239|Firmicutes E Amino acid polyamine organocation transporter, APC superfamily - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease,AA_permease_2 SRR21617311_k127_2412763_1 1379698.RBG1_1C00001G0432 7.218e-60 223.0 2BV2G@1|root,32QFC@2|Bacteria,2NR6X@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2412763_0 1379698.RBG1_1C00001G0285 2.166e-84 285.0 COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria 2|Bacteria K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N SRR21617311_k127_2412763_2 745014.OMB55_00018660 8.363e-10 60.0 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_2416105_0 1379698.RBG1_1C00001G1032 2.06e-50 193.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_2420710_0 1379698.RBG1_1C00001G1061 1.38e-222 701.0 COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria 2|Bacteria C NADH-quinone oxidoreductase, chain M nuoM-1 - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M SRR21617311_k127_2420710_1 1379698.RBG1_1C00001G1062 2.72e-15 81.0 COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN-1 - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M SRR21617311_k127_2430511_0 1379698.RBG1_1C00001G1366 3.681e-106 355.0 COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_2430511_1 1379698.RBG1_1C00001G1367 5.628e-85 287.0 COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria 2|Bacteria V COGs COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_2431664_0 1379698.RBG1_1C00001G1879 6.607e-209 661.0 COG1154@1|root,COG1154@2|Bacteria,2NNNA@2323|unclassified Bacteria 2|Bacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C SRR21617311_k127_2440284_0 1232410.KI421415_gene3125 9.344e-50 184.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_2440284_1 1144275.COCOR_02322 5.578e-44 167.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 SRR21617311_k127_2440517_1 1379698.RBG1_1C00001G0985 6.207e-44 166.0 COG1402@1|root,COG1402@2|Bacteria,2NRF3@2323|unclassified Bacteria 2|Bacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase SRR21617311_k127_2440517_0 1379698.RBG1_1C00001G1108 1.127e-107 355.0 COG1191@1|root,COG1191@2|Bacteria,2NPMN@2323|unclassified Bacteria 2|Bacteria K Sigma-70 region 3 - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR21617311_k127_2440517_3 1278309.KB907108_gene1558 4.109e-07 63.0 COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria 1224|Proteobacteria S Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh SRR21617311_k127_2448313_3 1499967.BAYZ01000090_gene4941 3.967e-20 103.0 2DDA6@1|root,2ZH98@2|Bacteria 2|Bacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT SRR21617311_k127_2448313_1 1123276.KB893276_gene2365 2.462e-61 220.0 COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47UDR@768503|Cytophagia 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SRR21617311_k127_2448313_0 1379698.RBG1_1C00001G1254 1.809e-140 459.0 COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria 2|Bacteria U Secretin and TonB N terminus short domain - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N SRR21617311_k127_2448313_4 1379698.RBG1_1C00001G1256 1.45e-14 75.0 COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria 2|Bacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO SRR21617311_k127_2459926_0 1379698.RBG1_1C00001G0519 1.407e-73 255.0 COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria 2|Bacteria EG EamA-like transporter family pagO - - ko:K07790 ko02020,map02020 - - - ko00000,ko00001 2.A.7 - - EamA SRR21617311_k127_2459926_3 518766.Rmar_2626 2.437e-21 109.0 COG0729@1|root,COG0729@2|Bacteria 2|Bacteria M surface antigen - - - ko:K07277,ko:K07278 - - - - ko00000,ko02000,ko03029 1.B.33,1.B.33.2.4 - - Bac_surface_Ag,POTRA,Peptidase_S74 SRR21617311_k127_2459926_4 382245.ASA_0977 6.108e-19 95.0 2DZND@1|root,32VEJ@2|Bacteria,1N2ZR@1224|Proteobacteria,1S9ST@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - NIPSNAP SRR21617311_k127_2459926_1 1267534.KB906757_gene1165 5.056e-28 115.0 2B1QU@1|root,31U6H@2|Bacteria,3Y5EE@57723|Acidobacteria,2JJUF@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF3224) - - - - - - - - - - - - DUF3224 SRR21617311_k127_246175_0 1379698.RBG1_1C00001G0445 0.0 1247.0 COG0542@1|root,COG0542@2|Bacteria,2NNKN@2323|unclassified Bacteria 2|Bacteria O C-terminal, D2-small domain, of ClpB protein clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR SRR21617311_k127_246175_1 1379698.RBG1_1C00001G0479 3.797e-183 596.0 COG0515@1|root,COG0515@2|Bacteria 1379698.RBG1_1C00001G0479|- KLT protein kinase activity - - - - - - - - - - - - - SRR21617311_k127_2480295_0 1379698.RBG1_1C00001G1654 6.407e-85 284.0 COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria 2|Bacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SRR21617311_k127_2480295_6 391596.PBAL39_11170 3.224e-27 119.0 COG3620@1|root,COG3620@2|Bacteria,4NW4Z@976|Bacteroidetes,1IZCW@117747|Sphingobacteriia 976|Bacteroidetes K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 SRR21617311_k127_2480295_10 1122604.JONR01000034_gene418 0.0002488 47.0 295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2480295_4 450851.PHZ_c2869 8.418e-32 136.0 COG1266@1|root,COG1266@2|Bacteria,1NXKQ@1224|Proteobacteria 1224|Proteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi SRR21617311_k127_2480295_3 102232.GLO73106DRAFT_00031820 5.38e-51 196.0 COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria 1117|Cyanobacteria Q FG-GAP repeat - - - - - - - - - - - - FG-GAP SRR21617311_k127_2480295_2 945713.IALB_0843 4.173e-75 290.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - CelD_N,Glyco_hydro_9,Laminin_G_3 SRR21617311_k127_2480295_5 449447.MAE_21930 1.756e-29 139.0 2DU7S@1|root,33P96@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2480295_1 1379698.RBG1_1C00001G1654 4.843e-84 281.0 COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria 2|Bacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SRR21617311_k127_2480295_7 391596.PBAL39_11170 1.512e-09 64.0 COG3620@1|root,COG3620@2|Bacteria,4NW4Z@976|Bacteroidetes,1IZCW@117747|Sphingobacteriia 976|Bacteroidetes K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 SRR21617311_k127_2480295_8 509635.N824_11095 5.398e-09 60.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding mutR - - ko:K20373,ko:K20374 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3,HTH_31 SRR21617311_k127_2486559_0 1123376.AUIU01000014_gene636 7.615e-141 471.0 COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae 40117|Nitrospirae G Glycosyl hydrolase family 57 - - - - - - - - - - - - Glyco_hydro_57 SRR21617311_k127_2486559_1 1379698.RBG1_1C00001G0405 2.025e-80 277.0 COG4784@1|root,COG4784@2|Bacteria,2NS4E@2323|unclassified Bacteria 2|Bacteria S Peptidase family M48 MA20_40030 - - - - - - - - - - - LysM,Peptidase_M48 SRR21617311_k127_2487692_1 1296416.JACB01000029_gene4193 0.0005965 51.0 COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1HYSA@117743|Flavobacteriia,2YHCW@290174|Aquimarina 976|Bacteroidetes M Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157,Endonuclea_NS_2 SRR21617311_k127_2487692_0 1122604.JONR01000001_gene1733 2.755e-14 76.0 COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,1S7VY@1236|Gammaproteobacteria,1X7TZ@135614|Xanthomonadales 135614|Xanthomonadales S Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_2 SRR21617311_k127_2515486_2 906968.Trebr_2205 0.0007936 44.0 COG1472@1|root,COG1472@2|Bacteria,2J5CS@203691|Spirochaetes 203691|Spirochaetes G Glycosyl hydrolase family 3 - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 SRR21617311_k127_2515486_0 1379698.RBG1_1C00001G0325 7.417e-125 417.0 COG2199@1|root,COG3706@2|Bacteria,2NPJ3@2323|unclassified Bacteria 2|Bacteria T diguanylate cyclase - - - - - - - - - - - - GAF,GAF_2,GAF_3,GGDEF,MASE3,PAS_3,PAS_4,Response_reg SRR21617311_k127_2515486_1 307480.IW16_10995 1.564e-08 61.0 29C0C@1|root,2ZYYV@2|Bacteria,4NVSG@976|Bacteroidetes,1II9S@117743|Flavobacteriia,3ZSB0@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_2515691_1 1379698.RBG1_1C00001G1883 7.179e-52 192.0 COG4932@1|root,COG4932@2|Bacteria,2NRTX@2323|unclassified Bacteria 2|Bacteria M Carboxypeptidase regulatory-like domain - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CarboxypepD_reg,Cna_B SRR21617311_k127_2515691_0 309799.DICTH_0388 4.855e-96 326.0 COG1249@1|root,COG1249@2|Bacteria 2|Bacteria C cell redox homeostasis lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0015036,GO:0016020,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035639,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044455,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0045271,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046686,GO:0046872,GO:0046914,GO:0048037,GO:0048046,GO:0050660,GO:0050662,GO:0050896,GO:0050897,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0070469,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.16.1.1,1.8.1.4 ko:K00382,ko:K00520 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_1869,iE2348C_1286.E2348C_4372,iEcolC_1368.EcolC_3543,iJN746.PP_4187,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim SRR21617311_k127_2545364_2 1379698.RBG1_1C00001G1789 4.302e-40 160.0 COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria 2|Bacteria S Propeptide_C25 porU - - - - - - - - - - - Peptidase_C25 SRR21617311_k127_2545364_0 1303518.CCALI_01682 9.601e-144 462.0 COG1830@1|root,COG1830@2|Bacteria 2|Bacteria G lyase activity fbaB - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC SRR21617311_k127_2545364_1 880073.Calab_3483 3.33e-133 433.0 COG3033@1|root,COG3033@2|Bacteria,2NNZV@2323|unclassified Bacteria 2|Bacteria E Beta-eliminating lyase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase SRR21617311_k127_2560618_1 1379698.RBG1_1C00001G0235 1.392e-37 147.0 COG0607@1|root,COG0607@2|Bacteria,2NRY7@2323|unclassified Bacteria 2|Bacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese SRR21617311_k127_2560618_2 1121405.dsmv_3549 8.882e-30 124.0 COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria,2MPU2@213118|Desulfobacterales 28221|Deltaproteobacteria S DoxX - - - - - - - - - - - - MauE SRR21617311_k127_2560618_4 593750.Metfor_1912 1.43e-23 114.0 arCOG00787@1|root,arCOG00787@2157|Archaea 2157|Archaea L UvrD REP helicase - - - ko:K07465 - - - - ko00000 - - - PDDEXK_1 SRR21617311_k127_2560618_0 760568.Desku_0507 6.58e-65 232.0 COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae 186801|Clostridia S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC SRR21617311_k127_2560618_3 316067.Geob_1385 4.271e-29 117.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales 28221|Deltaproteobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC SRR21617311_k127_2561407_0 929562.Emtol_2801 6.222e-47 175.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SRR21617311_k127_2564863_0 635013.TherJR_2221 3.063e-39 168.0 COG4409@1|root,COG4733@1|root,COG4409@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - ASH,BNR_2,CBM_35,DUF1080,F5_F8_type_C,PKD SRR21617311_k127_2564863_1 665959.HMPREF1013_03085 4.643e-17 92.0 COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes,4IQ7U@91061|Bacilli,1ZRHV@1386|Bacillus 91061|Bacilli S NHL repeat - - - - - - - - - - - - NHL SRR21617311_k127_2569973_0 1379698.RBG1_1C00001G1263 4.567e-97 339.0 COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria 2|Bacteria O Subtilase family aprN - - - - - - - - - - - Peptidase_S8 SRR21617311_k127_2569973_3 880073.Calab_3451 0.0001021 55.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane SRR21617311_k127_2569973_1 224325.AF_1483 2.499e-36 156.0 arCOG03567@1|root,arCOG07605@1|root,arCOG03567@2157|Archaea,arCOG07605@2157|Archaea,2Y7PW@28890|Euryarchaeota 28890|Euryarchaeota T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 SRR21617311_k127_2569973_2 439235.Dalk_4189 2.589e-06 59.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 SRR21617311_k127_2570145_0 1379698.RBG1_1C00001G0864 1.193e-81 282.0 COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria 2|Bacteria M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744,ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC,OstA,OstA_C SRR21617311_k127_2570724_1 1437425.CSEC_0969 8.57e-116 381.0 COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae 204428|Chlamydiae P Phosphate transporter family - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 SRR21617311_k127_2570724_2 1379698.RBG1_1C00001G0363 1.481e-73 253.0 COG1392@1|root,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria 2|Bacteria P Protein of unknown function DUF47 MA20_27875 - - ko:K02039,ko:K07220 - - - - ko00000 - - - PhoU_div SRR21617311_k127_2570724_0 1379698.RBG1_1C00001G0361 1.911e-133 439.0 COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria 2|Bacteria P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex SRR21617311_k127_2570724_4 642492.Clole_3019 4.009e-12 75.0 COG3448@1|root,COG3448@2|Bacteria,1UJ4A@1239|Firmicutes 1239|Firmicutes T PFAM CBS domain containing protein - - - - - - - - - - - - CBS SRR21617311_k127_2576746_0 1379698.RBG1_1C00001G1795 1.21e-185 592.0 COG0160@1|root,COG0160@2|Bacteria,2NNRV@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class-III argD - 2.6.1.19,2.6.1.33,2.6.1.36 ko:K00823,ko:K03918,ko:K20428 ko00250,ko00410,ko00525,ko00640,ko00650,ko01100,ko01120,ko01130,map00250,map00410,map00525,map00640,map00650,map01100,map01120,map01130 M00027 R00457,R00908,R01648,R02773 RC00006,RC00062,RC00781 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SRR21617311_k127_2576746_1 1379698.RBG1_1C00001G1794 6.105e-92 314.0 COG4448@1|root,COG4448@2|Bacteria 2|Bacteria E L-asparaginase II ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase_II SRR21617311_k127_2576746_2 1121121.KB894310_gene3895 5.466e-29 117.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,4HEYP@91061|Bacilli,271RB@186822|Paenibacillaceae 91061|Bacilli E Beta-eliminating lyase - - - - - - - - - - - - Beta_elim_lyase SRR21617311_k127_2578286_2 696369.KI912183_gene704 2.67e-10 62.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae 186801|Clostridia F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SRR21617311_k127_2578286_1 1379698.RBG1_1C00001G1132 1.137e-30 128.0 COG0558@1|root,COG0558@2|Bacteria,2NQ32@2323|unclassified Bacteria 2|Bacteria I CDP-alcohol phosphatidyltransferase pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SRR21617311_k127_2578286_0 1379698.RBG1_1C00001G1131 1.593e-133 448.0 COG0497@1|root,COG0497@2|Bacteria,2NNUS@2323|unclassified Bacteria 2|Bacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631,ko:K07459,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000,ko03400 3.A.1.112,8.A.1 - - SMC_N,YkyA SRR21617311_k127_2588308_7 1379698.RBG1_1C00001G1853 9.128e-29 119.0 COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria 2|Bacteria M Nucleotidyl transferase - - 2.3.1.157,2.7.7.23,2.7.7.24 ko:K00973,ko:K04042 ko00520,ko00521,ko00523,ko00525,ko01100,ko01130,map00520,map00521,map00523,map00525,map01100,map01130 M00362,M00793 R00416,R02328,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SRR21617311_k127_2588308_4 1379698.RBG1_1C00001G1620 1.573e-89 308.0 COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria 2|Bacteria M Bacterial phospho-glucose isomerase C-terminal SIS domain pgi - 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - SIS,bact-PGI_C SRR21617311_k127_2588308_1 521098.Aaci_0225 2.328e-114 389.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C SRR21617311_k127_2588308_8 1379698.RBG1_1C00001G1622 3.31e-25 114.0 COG1925@1|root,COG1925@2|Bacteria,2NQ6X@2323|unclassified Bacteria 2|Bacteria G PTS HPr component phosphorylation site ptsH - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr SRR21617311_k127_2588308_2 1379698.RBG1_1C00001G1623 9.263e-103 354.0 COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria 2|Bacteria LU DNA recombination-mediator protein A dprA - 5.99.1.2 ko:K03168,ko:K04096 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_processg_A SRR21617311_k127_2588308_0 1121430.JMLG01000002_gene982 1.288e-115 381.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae 186801|Clostridia S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 SRR21617311_k127_2588308_6 1123376.AUIU01000011_gene928 2.873e-65 231.0 COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae 40117|Nitrospirae S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N SRR21617311_k127_2588308_3 1379698.RBG1_1C00001G1625 1.78e-93 316.0 COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind SRR21617311_k127_2588308_5 246194.CHY_0955 2.402e-68 236.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,42EVI@68295|Thermoanaerobacterales 186801|Clostridia H PFAM GTP cyclohydrolase I Nitrile oxidoreductase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI SRR21617311_k127_2588308_9 1379698.RBG1_1C00001G1627 1.475e-19 90.0 COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SRR21617311_k127_2589705_0 880072.Desac_0946 2.261e-50 185.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MRJB@213462|Syntrophobacterales 28221|Deltaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SRR21617311_k127_2589705_2 1379698.RBG1_1C00001G1035 4.722e-46 184.0 COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2589705_4 1136417.AZWE01000039_gene1340 6.219e-05 55.0 COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D9MF@85008|Micromonosporales 201174|Actinobacteria NU Glycosyltransferase family 87 - - - ko:K13671 - - - - ko00000,ko01000,ko01003 - GT87 - GT87 SRR21617311_k127_2589705_1 1249627.D779_0808 1.186e-46 184.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RZRG@1236|Gammaproteobacteria,1WVXI@135613|Chromatiales 135613|Chromatiales M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2589705_3 926566.Terro_2757 2.814e-19 88.0 COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran SRR21617311_k127_2590277_3 1232410.KI421419_gene2513 1.204e-71 252.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,43SAR@69541|Desulfuromonadales 28221|Deltaproteobacteria C FAD linked oxidases, C-terminal domain larD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iAF987.Gmet_3245 FAD-oxidase_C,FAD_binding_4 SRR21617311_k127_2590277_4 562743.JH976443_gene3474 4.266e-09 64.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP SRR21617311_k127_2590277_1 880073.Calab_1379 1.459e-127 417.0 COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR21617311_k127_2590277_0 1444309.JAQG01000004_gene3593 2.149e-137 455.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,26QDD@186822|Paenibacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SRR21617311_k127_2590277_2 1265505.ATUG01000001_gene3729 2.9e-118 402.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MPQ1@213118|Desulfobacterales 28221|Deltaproteobacteria M Transglycosylase mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase SRR21617311_k127_2592629_2 1121430.JMLG01000013_gene1898 6.557e-84 292.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,26109@186807|Peptococcaceae 186801|Clostridia I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB SRR21617311_k127_2592629_10 264732.Moth_1827 4.608e-05 55.0 COG1396@1|root,COG1396@2|Bacteria,1V0UH@1239|Firmicutes,24F2M@186801|Clostridia,42FSQ@68295|Thermoanaerobacterales 186801|Clostridia K transcriptional regulator, XRE family - - - - - - - - - - - - HTH_3 SRR21617311_k127_2592629_8 864564.HMPREF0620_0952 2.629e-11 70.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR21617311_k127_2592629_0 1379698.RBG1_1C00001G0838 6.906e-149 480.0 COG2255@1|root,COG2255@2|Bacteria,2NNUG@2323|unclassified Bacteria 2|Bacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N SRR21617311_k127_2592629_4 1379698.RBG1_1C00001G0837 1.414e-47 178.0 COG0632@1|root,COG0632@2|Bacteria,2NPR6@2323|unclassified Bacteria 2|Bacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N SRR21617311_k127_2592629_5 880073.Calab_2589 1.808e-32 134.0 COG0817@1|root,COG0817@2|Bacteria,2NPKS@2323|unclassified Bacteria 2|Bacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC SRR21617311_k127_2592629_1 1379698.RBG1_1C00001G0835 3.212e-107 352.0 COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg SRR21617311_k127_2592629_3 1379698.RBG1_1C00001G0834 6.339e-69 244.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 SRR21617311_k127_2592629_11 521097.Coch_0811 0.0001963 51.0 COG3637@1|root,COG3637@2|Bacteria,4NRH8@976|Bacteroidetes,1I36J@117743|Flavobacteriia,1ES0D@1016|Capnocytophaga 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - ko:K07275 - - - - ko00000 - - - OMP_b-brl SRR21617311_k127_2592629_7 861299.J421_1299 6.871e-16 86.0 2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl SRR21617311_k127_2592629_12 926562.Oweho_2641 0.0001993 51.0 2DRPR@1|root,33CHJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - OMP_b-brl SRR21617311_k127_2592629_9 1379698.RBG1_1C00001G0830 4.214e-10 60.0 COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria 2|Bacteria J elongation factor G fusA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR21617311_k127_2593430_4 661367.LLO_3373 1.355e-05 51.0 COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,1SGI6@1236|Gammaproteobacteria,1JDMF@118969|Legionellales 118969|Legionellales C Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - - SRR21617311_k127_2593430_1 28072.Nos7524_0032 7.52e-95 336.0 COG2931@1|root,COG2931@2|Bacteria,1GIZT@1117|Cyanobacteria,1HMI7@1161|Nostocales 1117|Cyanobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind,VCBS SRR21617311_k127_2593430_3 1137269.AZWL01000015_gene738 1.816e-24 104.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria 201174|Actinobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SRR21617311_k127_2593430_0 498761.HM1_0977 1.719e-146 475.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia 186801|Clostridia F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt SRR21617311_k127_2593430_2 555088.DealDRAFT_1047 4.971e-33 133.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,42JZD@68298|Syntrophomonadaceae 186801|Clostridia D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 SRR21617311_k127_2607556_1 1379698.RBG1_1C00001G1494 1.31e-122 400.0 COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria 2|Bacteria F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SRR21617311_k127_2607556_3 1396141.BATP01000056_gene3118 3.291e-33 134.0 COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae 203494|Verrucomicrobiae KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase SRR21617311_k127_2607556_6 1121904.ARBP01000002_gene6681 6.554e-26 114.0 COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 SRR21617311_k127_2607556_4 1031711.RSPO_c03231 1.951e-30 122.0 COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria,1K8BT@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM GYD family protein - - - - - - - - - - - - GYD SRR21617311_k127_2607556_5 1089544.KB912942_gene490 1.504e-28 118.0 COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales 201174|Actinobacteria S PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily - - - ko:K06996 - - - - ko00000 - - - Glyoxalase SRR21617311_k127_2607556_0 1232410.KI421428_gene1205 7.169e-132 430.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,43S43@69541|Desulfuromonadales 28221|Deltaproteobacteria I GcpE protein ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE SRR21617311_k127_2607556_7 1379698.RBG1_1C00001G0953 5.376e-21 101.0 COG0792@1|root,COG0792@2|Bacteria,2NPW8@2323|unclassified Bacteria 2|Bacteria L Nuclease-related domain yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 SRR21617311_k127_2607556_2 1379698.RBG1_1C00001G0952 5.168e-54 198.0 COG0164@1|root,COG0164@2|Bacteria,2NPD1@2323|unclassified Bacteria 2|Bacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SRR21617311_k127_2623291_2 1379698.RBG1_1C00001G0211 6.651e-21 96.0 COG0457@1|root,COG0457@2|Bacteria,2NQ8S@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_2623291_0 1047013.AQSP01000104_gene1408 2.996e-99 341.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain pepN - - - - - - - - - - - Peptidase_M1 SRR21617311_k127_2623427_3 644283.Micau_2499 3.659e-21 101.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1 SRR21617311_k127_2623427_2 1379698.RBG1_1C00001G0336 2.317e-56 205.0 COG5588@1|root,COG5588@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 SRR21617311_k127_2623427_0 1379698.RBG1_1C00001G0513 3.579e-161 518.0 COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria 2|Bacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA3 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like SRR21617311_k127_2623427_1 1379698.RBG1_1C00001G0512 7.144e-139 451.0 COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria 2|Bacteria I Dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SRR21617311_k127_262470_1 1492737.FEM08_06580 3.684e-67 235.0 COG0573@1|root,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,1HYFF@117743|Flavobacteriia,2NS7H@237|Flavobacterium 976|Bacteroidetes P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,PBP_like_2 SRR21617311_k127_262470_0 290397.Adeh_4004 6.677e-106 353.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales 28221|Deltaproteobacteria P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 SRR21617311_k127_2627650_0 1379698.RBG1_1C00001G1326 1.867e-159 511.0 COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria 2|Bacteria C Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362,Fer4 SRR21617311_k127_2627650_2 1501269.EW15_0049 1.07e-14 86.0 COG0457@1|root,COG4122@1|root,COG0457@2|Bacteria,COG4122@2|Bacteria,1G1UY@1117|Cyanobacteria,1MKXP@1212|Prochloraceae 1117|Cyanobacteria S Alternative locus ID - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_11,TPR_2,TPR_8 SRR21617311_k127_2627650_1 1379698.RBG1_1C00001G1332 2.174e-51 190.0 COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria 2|Bacteria T Anti-sigma factor antagonist - - - ko:K04749,ko:K06378 - - - - ko00000,ko03021 - - - STAS,STAS_2 SRR21617311_k127_2627650_3 929562.Emtol_4206 5.747e-10 64.0 COG1192@1|root,COG1192@2|Bacteria,4NTB9@976|Bacteroidetes,47RPG@768503|Cytophagia 976|Bacteroidetes D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SRR21617311_k127_2631438_5 1379698.RBG1_1C00001G1170 3.335e-25 113.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization CP_0079 - - ko:K15368 - - - - ko00000 - - - TPR_16,TPR_21,TPR_6 SRR21617311_k127_2631438_3 1379698.RBG1_1C00001G1171 4.374e-48 191.0 COG2067@1|root,COG2067@2|Bacteria,2NRR0@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X SRR21617311_k127_2631438_2 330214.NIDE0858 6.211e-68 238.0 COG0745@1|root,COG0745@2|Bacteria,3J0JU@40117|Nitrospirae 40117|Nitrospirae K Transcriptional regulatory protein, C terminal - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SRR21617311_k127_2631438_1 443143.GM18_1480 2.078e-88 314.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales 28221|Deltaproteobacteria T Phosphate sensor histidine kinase, HAMP and PAS domain-containing phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like SRR21617311_k127_2631438_4 215803.DB30_0085 2.55e-41 168.0 COG3746@1|root,COG3746@2|Bacteria,1PBWD@1224|Proteobacteria,433TT@68525|delta/epsilon subdivisions,2X3F8@28221|Deltaproteobacteria,2YVU2@29|Myxococcales 28221|Deltaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - SRR21617311_k127_2631438_0 290397.Adeh_4006 8.604e-107 353.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales 28221|Deltaproteobacteria P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 SRR21617311_k127_2631438_6 498761.HM1_2083 4.152e-09 61.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia 186801|Clostridia P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SRR21617311_k127_2634331_3 1379698.RBG1_1C00001G1180 1.096e-28 117.0 COG1160@1|root,COG1160@2|Bacteria,2NNTW@2323|unclassified Bacteria 2|Bacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 SRR21617311_k127_2634331_1 1379698.RBG1_1C00001G1240 1.958e-135 445.0 COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria 2|Bacteria P MgtE intracellular N domain opuCA - 3.6.3.32 ko:K02000,ko:K05847 ko02010,map02010 M00208,M00209 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - iSB619.SA_RS12845 ABC_tran,CBS,MgtE_N,PRC SRR21617311_k127_2634331_4 84531.JMTZ01000033_gene282 0.0002281 47.0 2ASNB@1|root,31I32@2|Bacteria,1QFS7@1224|Proteobacteria,1TD1Z@1236|Gammaproteobacteria,1X8TG@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR21617311_k127_2634331_0 1379698.RBG1_1C00001G1241 5.051e-137 449.0 COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria 2|Bacteria S PHP domain protein - - - - - - - - - - - - PHP SRR21617311_k127_2634331_2 1379698.RBG1_1C00001G1242 1.505e-29 121.0 COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria 2|Bacteria S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22,MFS_1 SRR21617311_k127_2641096_11 1247024.JRLH01000001_gene1010 1.112e-08 60.0 2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2641096_10 1137281.D778_02430 4.33e-10 63.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_2641096_2 1379698.RBG1_1C00001G0208 7.747e-122 416.0 COG2304@1|root,COG2304@2|Bacteria,2NPT8@2323|unclassified Bacteria 2|Bacteria S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA SRR21617311_k127_2641096_4 1379698.RBG1_1C00001G0213 2.404e-89 304.0 COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria 2|Bacteria EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iHN637.CLJU_RS07505,iIT341.HP0330,iLF82_1304.LF82_1103 IlvC,IlvN SRR21617311_k127_2641096_0 1379698.RBG1_1C00001G0215 4.217e-148 479.0 COG0577@1|root,COG0577@2|Bacteria,2NP20@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_2641096_3 1379698.RBG1_1C00001G0216 2.013e-102 349.0 COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria 2|Bacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_D23 SRR21617311_k127_2641096_8 525904.Tter_0166 5.82e-22 102.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase - - 3.6.1.13,3.6.1.67 ko:K01515,ko:K08310 ko00230,ko00790,map00230,map00790 M00126 R01054,R04638 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NUDIX SRR21617311_k127_2641096_1 768710.DesyoDRAFT_3280 4.906e-129 436.0 COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,261CV@186807|Peptococcaceae 186801|Clostridia C UPF0313 protein - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N SRR21617311_k127_2641096_6 574087.Acear_0301 2.008e-43 167.0 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,24J1S@186801|Clostridia 186801|Clostridia S PFAM LmbE family protein - - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L SRR21617311_k127_2641096_5 1379698.RBG1_1C00001G1771 1.259e-61 227.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SRR21617311_k127_2641096_9 439235.Dalk_2686 5.359e-13 77.0 COG1225@1|root,COG3832@1|root,COG1225@2|Bacteria,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity - - - - - - - - - - - - AhpC-TSA,Polyketide_cyc2 SRR21617311_k127_2641096_7 1047013.AQSP01000138_gene1077 3.876e-30 132.0 COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria 2|Bacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP SRR21617311_k127_2643720_2 1379698.RBG1_1C00001G0632 1.581e-17 83.0 COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria 2|Bacteria T STAS domain rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 SRR21617311_k127_2643720_4 264732.Moth_0242 7.568e-06 55.0 COG5492@1|root,COG5492@2|Bacteria,1VX4D@1239|Firmicutes,252B8@186801|Clostridia 186801|Clostridia N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,TIG SRR21617311_k127_2643720_0 670487.Ocepr_2229 3.695e-52 192.0 COG1943@1|root,COG1943@2|Bacteria,1WMVN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase IS200 like - - - - - - - - - - - - - SRR21617311_k127_2643720_1 269799.Gmet_2517 5.415e-32 141.0 COG1538@1|root,COG1538@2|Bacteria,1QY91@1224|Proteobacteria,42Q4F@68525|delta/epsilon subdivisions,2WJMF@28221|Deltaproteobacteria 28221|Deltaproteobacteria MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP SRR21617311_k127_2646994_2 1379698.RBG1_1C00001G0736 1.666e-99 327.0 COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria 2|Bacteria O FeS assembly protein SufB sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 SRR21617311_k127_2646994_1 1379698.RBG1_1C00001G0735 2.851e-121 393.0 COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria 2|Bacteria O ABC transporter sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran SRR21617311_k127_2646994_3 1379698.RBG1_1C00001G0734 1.265e-57 205.0 COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 SRR21617311_k127_2646994_5 316056.RPC_3289 1.965e-48 182.0 28QM9@1|root,2ZD31@2|Bacteria,1NUK0@1224|Proteobacteria,2URK9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 SRR21617311_k127_2646994_4 1144275.COCOR_07943 8.208e-52 189.0 COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SRR21617311_k127_2646994_0 1379698.RBG1_1C00001G1237 5.436e-143 462.0 COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains zraR GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_2648313_1 1379698.RBG1_1C00001G1324 5.199e-116 384.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2NNZJ@2323|unclassified Bacteria 2|Bacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K00082,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1624 RibD_C,dCMP_cyt_deam_1 SRR21617311_k127_2648313_2 517417.Cpar_1317 3.439e-57 206.0 COG0307@1|root,COG0307@2|Bacteria,1FDVH@1090|Chlorobi 1090|Chlorobi H TIGRFAM riboflavin synthase, alpha subunit - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding SRR21617311_k127_2648313_0 1379698.RBG1_1C00001G1322 4.306e-153 496.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2NNKV@2323|unclassified Bacteria 2|Bacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS10830,iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 SRR21617311_k127_2648313_3 1191523.MROS_1962 7.345e-57 202.0 COG0054@1|root,COG0054@2|Bacteria 2|Bacteria H 6,7-dimethyl-8-ribityllumazine synthase activity ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 DMRL_synthase SRR21617311_k127_2648313_4 1379698.RBG1_1C00001G1320 7.146e-30 123.0 COG0781@1|root,COG0781@2|Bacteria,2NPZI@2323|unclassified Bacteria 2|Bacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB SRR21617311_k127_2648313_5 1379698.RBG1_1C00001G0356 8.889e-23 100.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria 2|Bacteria EG Protein of unknown function (DUF2723) - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT SRR21617311_k127_2654583_0 1379698.RBG1_1C00001G1206 8.325e-108 362.0 COG1215@1|root,COG1215@2|Bacteria,2NQN7@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase like family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SRR21617311_k127_2656069_2 1379698.RBG1_1C00001G1351 9.167e-38 145.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SRR21617311_k127_2656069_1 1379698.RBG1_1C00001G1352 1.796e-74 258.0 COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria 2|Bacteria P ZIP Zinc transporter zupT - - ko:K07238,ko:K11021,ko:K16267 - - - - ko00000,ko02000,ko02042 2.A.5.4.11,2.A.5.5 - - Zip SRR21617311_k127_2656069_0 1116375.VEJY3_23976 2.451e-82 299.0 COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria,1XTRH@135623|Vibrionales 135623|Vibrionales M Immune inhibitor A peptidase M6 prtV GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - PKD,Peptidase_M6 SRR21617311_k127_2663247_2 1379698.RBG1_1C00001G1516 1.748e-64 234.0 COG2982@1|root,COG2982@2|Bacteria,2NRT5@2323|unclassified Bacteria 2|Bacteria M AsmA-like C-terminal region - - - ko:K07289,ko:K09800 - - - - ko00000,ko02000 - - - AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH SRR21617311_k127_2663247_4 1379698.RBG1_1C00001G1515 9.671e-41 166.0 COG0457@1|root,COG0457@2|Bacteria 1379698.RBG1_1C00001G1515|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SRR21617311_k127_2663247_3 1379698.RBG1_1C00001G1514 1.837e-54 203.0 COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria 2|Bacteria M Lipid A biosynthesis htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SRR21617311_k127_2663247_1 880073.Calab_1580 1.721e-68 248.0 COG0845@1|root,COG0845@2|Bacteria,2NR8R@2323|unclassified Bacteria 2|Bacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23 SRR21617311_k127_2663247_0 1499967.BAYZ01000019_gene6326 3.717e-104 353.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,2NP20@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain macB_1 - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD SRR21617311_k127_2663438_0 1379698.RBG1_1C00001G1619 1.078e-95 319.0 COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria 2|Bacteria O Cytochrome C biogenesis protein transmembrane region ccdA - 1.8.4.11,1.8.4.12 ko:K06196,ko:K12267 - - - - ko00000,ko01000,ko02000 5.A.1.2 - - AhpC-TSA,DsbD SRR21617311_k127_2663438_2 1379698.RBG1_1C00001G1618 5.209e-55 199.0 COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma factor sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_2663438_4 1463845.JOIG01000006_gene902 4.795e-06 54.0 COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria 201174|Actinobacteria K AntiSigma factor rsrA GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - - - - - - - - - - zf-HC2 SRR21617311_k127_2663438_3 237368.SCABRO_03987 3.104e-39 156.0 COG3222@1|root,COG3222@2|Bacteria,2J0B9@203682|Planctomycetes 203682|Planctomycetes S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 SRR21617311_k127_2663438_1 1340493.JNIF01000004_gene858 2.778e-57 207.0 COG1402@1|root,COG1402@2|Bacteria 2|Bacteria I creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase SRR21617311_k127_2664176_1 1191523.MROS_1825 8.769e-25 114.0 COG4412@1|root,COG4447@1|root,COG4412@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - DUF4859,FlgD_ig,PSII_BNR SRR21617311_k127_2664176_0 1379698.RBG1_1C00001G0581 6.461e-68 258.0 COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - - - - - - - - - - - ASH,Cohesin,FlgD_ig,Peptidase_S74 SRR21617311_k127_2666961_2 643867.Ftrac_3722 6.474e-20 93.0 COG1932@1|root,COG1932@2|Bacteria,4PM2C@976|Bacteroidetes,47Y07@768503|Cytophagia 976|Bacteroidetes EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 SRR21617311_k127_2666961_1 1089547.KB913013_gene2734 1.671e-124 430.0 COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia 976|Bacteroidetes EH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,HAD SRR21617311_k127_2666961_0 1379698.RBG1_1C00001G0608 2.756e-197 624.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N SRR21617311_k127_2673602_0 1379698.RBG1_1C00001G1815 1.83e-86 299.0 COG0477@1|root,COG2814@2|Bacteria,2NPJ1@2323|unclassified Bacteria 2|Bacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SRR21617311_k127_2673602_3 1497679.EP56_00605 8.15e-31 132.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,26IXZ@186820|Listeriaceae 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ SRR21617311_k127_2673602_1 1379698.RBG1_1C00001G1813 4.955e-58 210.0 COG0101@1|root,COG0101@2|Bacteria,2NPEC@2323|unclassified Bacteria 2|Bacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 SRR21617311_k127_2673602_2 1191523.MROS_1726 3.267e-33 130.0 COG0176@1|root,COG0176@2|Bacteria 2|Bacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA SRR21617311_k127_2677940_1 1267535.KB906767_gene3079 4.212e-79 276.0 COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia 204432|Acidobacteriia E NeuB family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 SRR21617311_k127_2677940_0 1379698.RBG1_1C00001G1534 5.937e-144 466.0 COG0018@1|root,COG0018@2|Bacteria,2NP0H@2323|unclassified Bacteria 2|Bacteria J Arginyl tRNA synthetase N terminal dom argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_1434,iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR21617311_k127_2679375_0 1379698.RBG1_1C00001G1367 1.558e-139 451.0 COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria 2|Bacteria V COGs COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_2679375_1 1379698.RBG1_1C00001G1368 3.746e-79 281.0 COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria 2|Bacteria KT Peptidase M56 - - - - - - - - - - - - Amidase_6,DUF4309,DUF5301 SRR21617311_k127_2681269_0 1379698.RBG1_1C00001G1476 4.84e-99 332.0 COG1703@1|root,COG1703@2|Bacteria,2NP56@2323|unclassified Bacteria 2|Bacteria E LAO AO transport system ATPase argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK SRR21617311_k127_2681269_1 1379698.RBG1_1C00001G1475 7.503e-68 240.0 COG1884@1|root,COG1884@2|Bacteria,2NNZ9@2323|unclassified Bacteria 2|Bacteria I Methylmalonyl-CoA mutase icmA - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase SRR21617311_k127_2683683_2 395493.BegalDRAFT_2517 4.666e-60 231.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - 3.4.24.3 ko:K01387,ko:K03301 - - - - ko00000,ko01000,ko01002,ko02042 2.A.12 - - DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase SRR21617311_k127_2683683_5 1174504.AJTN02000120_gene4835 6.978e-06 48.0 2BR4S@1|root,32K2S@2|Bacteria,1U1SU@1239|Firmicutes,4IB95@91061|Bacilli,1ZKR2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - SRR21617311_k127_2683683_3 192952.MM_3075 7.896e-43 161.0 COG1611@1|root,arCOG02431@2157|Archaea,2XXTK@28890|Euryarchaeota,2N9VX@224756|Methanomicrobia 224756|Methanomicrobia S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox SRR21617311_k127_2683683_4 945713.IALB_2263 6.758e-20 93.0 COG1254@1|root,COG1254@2|Bacteria 2|Bacteria C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase SRR21617311_k127_2683683_1 1379698.RBG1_1C00001G1172 2.067e-62 220.0 COG0503@1|root,COG0503@2|Bacteria,2NPGX@2323|unclassified Bacteria 2|Bacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - PRTase_2,Pribosyltran,TRSP SRR21617311_k127_2683683_0 1379698.RBG1_1C00001G0885 4.455e-146 481.0 COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria 2|Bacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338,ko:K08675 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002,ko03029 - - - AAA,LON_substr_bdg,Lon_C SRR21617311_k127_2690194_0 401526.TcarDRAFT_1870 5.453e-31 129.0 COG1376@1|root,COG1376@2|Bacteria,1TQAB@1239|Firmicutes,4H267@909932|Negativicutes 909932|Negativicutes S ErfK YbiS YcfS YnhG erfK - - - - - - - - - - - Cu_amine_oxidN1,YkuD SRR21617311_k127_2691311_1 665942.HMPREF1022_00536 8.734e-65 228.0 2E6F8@1|root,3312N@2|Bacteria,1NPJ2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2691311_0 1379698.RBG1_1C00001G1441 7.585e-309 956.0 COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria 2|Bacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 SRR21617311_k127_2691311_3 1379698.RBG1_1C00001G1439 4.667e-27 113.0 COG2331@1|root,COG2331@2|Bacteria,2NQ36@2323|unclassified Bacteria 2|Bacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 SRR21617311_k127_2691311_4 880073.Calab_2464 1.772e-13 76.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Beta-lactamase,DUF3471,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 SRR21617311_k127_2691311_2 292459.STH2430 4.357e-50 182.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia 186801|Clostridia J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase SRR21617311_k127_2691311_5 498761.HM1_2733 1.334e-07 61.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia 186801|Clostridia D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf SRR21617311_k127_2691384_2 1192034.CAP_8957 1.369e-40 161.0 COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales 28221|Deltaproteobacteria D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SRR21617311_k127_2691384_0 880073.Calab_0681 6.113e-170 568.0 COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria 2|Bacteria KT Sigma factor PP2C-like phosphatases pkn5 - 2.7.11.1,3.1.3.3 ko:K04757,ko:K07315 - - - - ko00000,ko01000,ko01001,ko03021 - - - AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1 SRR21617311_k127_2691384_1 1379698.RBG1_1C00001G1334 1.974e-59 222.0 COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria 2|Bacteria I Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SRR21617311_k127_2696074_0 1379698.RBG1_1C00001G0844 3.783e-171 546.0 COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c DALR_2,tRNA-synt_1e,tRNA-synt_1g SRR21617311_k127_2696074_2 1382358.JHVN01000020_gene1410 4.088e-113 380.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,21V1J@150247|Anoxybacillus 91061|Bacilli G M42 glutamyl aminopeptidase ysdC - - - - - - - - - - - Peptidase_M42 SRR21617311_k127_2696074_3 1379698.RBG1_1C00001G0843 4.922e-62 222.0 COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria 2|Bacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.1.3.5 ko:K07025,ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SRR21617311_k127_2696074_1 1379698.RBG1_1C00001G0842 5.886e-124 407.0 COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SRR21617311_k127_2696074_4 1379698.RBG1_1C00001G0841 6.524e-40 154.0 COG0586@1|root,COG0586@2|Bacteria,2NREP@2323|unclassified Bacteria 2|Bacteria S SNARE associated Golgi protein yngC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc SRR21617311_k127_2696677_0 589924.Ferp_0317 5.289e-126 413.0 COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi 183980|Archaeoglobi F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS SRR21617311_k127_2696677_2 1131814.JAFO01000001_gene4568 2.26e-26 111.0 COG0316@1|root,COG0316@2|Bacteria,1MZTE@1224|Proteobacteria,2UC0W@28211|Alphaproteobacteria,3F1IH@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Iron-sulphur cluster biosynthesis iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SRR21617311_k127_2696677_1 1379698.RBG1_1C00001G1873 5.721e-38 148.0 COG0379@1|root,COG0379@2|Bacteria,2NP47@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SRR21617311_k127_270095_1 1379698.RBG1_1C00001G1238 6.165e-16 85.0 COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria 2|Bacteria T COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1 SRR21617311_k127_270095_0 66429.JOFL01000003_gene3352 3.807e-24 107.0 COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria 201174|Actinobacteria L Belongs to the FPG family mutM1 - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SRR21617311_k127_2704420_1 1379698.RBG1_1C00001G0782 4.516e-109 360.0 COG0065@1|root,COG0065@2|Bacteria,2NP32@2323|unclassified Bacteria 2|Bacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC1 - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR21617311_k127_2704420_0 204669.Acid345_2713 4.35e-171 554.0 COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria 57723|Acidobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Cytochrom_c3_2,Ni_hydr_CYTB SRR21617311_k127_2708930_3 1379698.RBG1_1C00001G0519 5.06e-18 86.0 COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria 2|Bacteria EG EamA-like transporter family pagO - - ko:K07790 ko02020,map02020 - - - ko00000,ko00001 2.A.7 - - EamA SRR21617311_k127_2708930_1 1379698.RBG1_1C00001G0372 3.407e-158 533.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,2NP45@2323|unclassified Bacteria 2|Bacteria M Patatin-like phospholipase plpD - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin SRR21617311_k127_2708930_2 1379698.RBG1_1C00001G0371 1.364e-55 206.0 COG0566@1|root,COG0566@2|Bacteria,2NPZQ@2323|unclassified Bacteria 2|Bacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - 2.1.1.185 ko:K03218,ko:K03437 - - - - ko00000,ko01000,ko03009,ko03016 - - - SpoU_methylase,SpoU_sub_bind SRR21617311_k127_2708930_0 1379698.RBG1_1C00001G0370 4.918e-213 688.0 COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria 2|Bacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 SRR21617311_k127_2711655_2 1042877.GQS_09000 0.000808 52.0 arCOG02559@1|root,arCOG03264@1|root,arCOG08609@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG08609@2157|Archaea,2Y0CM@28890|Euryarchaeota,245E0@183968|Thermococci 183968|Thermococci S by modhmm - - - - - - - - - - - - DUF5122,PEGA SRR21617311_k127_2711655_0 404589.Anae109_3817 1.75e-55 206.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales 28221|Deltaproteobacteria T Protein serine threonine phosphatase pph1 - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 SRR21617311_k127_2711655_1 1348583.ATLH01000029_gene1170 3.63e-14 75.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia,1FAHT@104264|Cellulophaga 976|Bacteroidetes L PFAM Excinuclease ABC, C subunit, N-terminal - - - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_2722477_0 243231.GSU3608 1.015e-94 319.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter ybhF-N - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SRR21617311_k127_2722477_1 1449126.JQKL01000036_gene1950 1.547e-54 203.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_2723021_4 1191523.MROS_1662 3.408e-42 161.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 - R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 SRR21617311_k127_2723021_3 1379698.RBG1_1C00001G1426 3.258e-57 203.0 COG0251@1|root,COG0251@2|Bacteria,2NR4K@2323|unclassified Bacteria 2|Bacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Aldo_ket_red,Ribonuc_L-PSP SRR21617311_k127_2723021_5 518766.Rmar_1989 3.431e-32 133.0 COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1FJ9B@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Domain of unknown function (DUF1949) yigZ - - - - - - - - - - - UPF0029 SRR21617311_k127_2723021_1 1379698.RBG1_1C00001G0664 7.319e-70 247.0 COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria 2|Bacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A SRR21617311_k127_2723021_0 383372.Rcas_0343 4.275e-91 310.0 COG1446@1|root,COG1446@2|Bacteria,2G6AS@200795|Chloroflexi,37501@32061|Chloroflexia 32061|Chloroflexia E PFAM peptidase T2 asparaginase 2 - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 SRR21617311_k127_2723021_2 1191523.MROS_1741 1.69e-60 218.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria 2|Bacteria J transcription antitermination sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB SRR21617311_k127_2727124_0 118161.KB235922_gene927 7.672e-181 572.0 COG0156@1|root,COG0156@2|Bacteria,1GC2I@1117|Cyanobacteria,3VIWQ@52604|Pleurocapsales 1117|Cyanobacteria H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_2727124_1 1379698.RBG1_1C00001G0291 1.012e-48 179.0 COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria 2|Bacteria E Peptidase family M20/M25/M40 - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42 SRR21617311_k127_273073_3 1379698.RBG1_1C00001G1249 4.658e-73 256.0 COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria 2|Bacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 SRR21617311_k127_273073_2 1379698.RBG1_1C00001G1248 3.962e-84 295.0 COG1899@1|root,COG1899@2|Bacteria,2NP1S@2323|unclassified Bacteria 2|Bacteria O peptidyl-lysine modification to peptidyl-hypusine - - - - - - - - - - - - - SRR21617311_k127_273073_0 1379698.RBG1_1C00001G1247 3.329e-186 594.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria 2|Bacteria E Formiminotransferase-cyclodeaminase ftcD - 2.1.2.5,4.3.1.4 ko:K00603,ko:K01746,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N SRR21617311_k127_273073_1 1379698.RBG1_1C00001G1245 1.933e-85 307.0 COG1629@1|root,COG4771@2|Bacteria,2NRGW@2323|unclassified Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec SRR21617311_k127_273073_5 1121423.JONT01000032_gene2570 6.774e-06 55.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt SRR21617311_k127_2730751_3 1121413.JMKT01000001_gene1760 6.042e-62 222.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2M98I@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM oxidoreductase domain protein gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C SRR21617311_k127_2730751_2 1379698.RBG1_1C00001G1648 2.394e-105 347.0 COG1043@1|root,COG1043@2|Bacteria,2NP5V@2323|unclassified Bacteria 2|Bacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep SRR21617311_k127_2730751_0 1379698.RBG1_1C00001G1649 6.196e-218 684.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria 2|Bacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 - - - FabA,LpxC SRR21617311_k127_2730751_4 858619.CVAR_2228 1.446e-09 66.0 COG4758@1|root,COG4758@2|Bacteria,2GU2Z@201174|Actinobacteria,22NRZ@1653|Corynebacteriaceae 201174|Actinobacteria S membrane - - - - - - - - - - - - DUF1707,DUF2154 SRR21617311_k127_2730751_1 1379698.RBG1_1C00001G0907 1.311e-171 539.0 COG1024@1|root,COG1024@2|Bacteria 2|Bacteria I Enoyl-CoA hydratase bamA GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 ko:K07539,ko:K18570 ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220 M00541 R05593,R05594,R10696,R10750 RC01430,RC01431,RC03237,RC03270 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SRR21617311_k127_2744620_4 1379698.RBG1_1C00001G0479 9.959e-12 67.0 COG0515@1|root,COG0515@2|Bacteria 1379698.RBG1_1C00001G0479|- KLT protein kinase activity - - - - - - - - - - - - - SRR21617311_k127_2744620_1 1379698.RBG1_1C00001G0480 5.535e-83 282.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain apaH - - - - - - - - - - - Metallophos_2 SRR21617311_k127_2744620_0 1379698.RBG1_1C00001G0481 7.555e-95 316.0 COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria 2|Bacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - DUF3662,DUF4388,FHA,Yop-YscD_cpl SRR21617311_k127_2744620_2 1379698.RBG1_1C00001G0482 1.495e-77 274.0 COG1691@1|root,COG1691@2|Bacteria,2NPQT@2323|unclassified Bacteria 2|Bacteria S AIR carboxylase cpmA - - ko:K06898 - - - - ko00000 - - - AIRC SRR21617311_k127_2744620_3 871963.Desdi_2304 5.393e-29 122.0 COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,260FF@186807|Peptococcaceae 186801|Clostridia S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 SRR21617311_k127_2746828_0 1379698.RBG1_1C00001G0402 4.237e-126 419.0 COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria 2|Bacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge SRR21617311_k127_2746828_2 471853.Bcav_1599 1.014e-19 89.0 COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 SRR21617311_k127_2746828_1 1379698.RBG1_1C00001G0745 5.688e-116 383.0 COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 SRR21617311_k127_2760767_3 1379698.RBG1_1C00001G1299 1.05e-95 317.0 COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria 2|Bacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 SRR21617311_k127_2760767_0 1379698.RBG1_1C00001G1298 3.366e-267 831.0 COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria 2|Bacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cyoB GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0040007,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 ko:K02274,ko:K02298,ko:K02827,ko:K15408 ko00190,ko01100,map00190,map01100 M00155,M00416,M00417 R00081,R09492,R11335 RC00016,RC00061,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 - - COX1 SRR21617311_k127_2760767_6 1415778.JQMM01000001_gene1698 5.619e-39 161.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1TH2Y@1236|Gammaproteobacteria,1J4CC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA SRR21617311_k127_2760767_1 1379698.RBG1_1C00001G1296 2.437e-120 392.0 COG0109@1|root,COG0109@2|Bacteria,2NPBW@2323|unclassified Bacteria 2|Bacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA SRR21617311_k127_2760767_4 1379698.RBG1_1C00001G1295 5.375e-59 209.0 COG3175@1|root,COG3175@2|Bacteria 2|Bacteria O copper ion binding ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 SRR21617311_k127_2760767_2 1379698.RBG1_1C00001G1293 6.198e-101 335.0 COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria 2|Bacteria C cytochrome c oxidase subunit III ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - iJN678.ctaE COX3 SRR21617311_k127_2760767_5 264732.Moth_0875 5.023e-57 207.0 COG0842@1|root,COG0842@2|Bacteria,1TSWD@1239|Firmicutes,24EPB@186801|Clostridia 186801|Clostridia V PFAM ABC-2 type transporter - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane SRR21617311_k127_2762903_0 1379698.RBG1_1C00001G1085 8.07e-67 231.0 COG2109@1|root,COG2109@2|Bacteria,2NPNR@2323|unclassified Bacteria 2|Bacteria H ATP:corrinoid adenosyltransferase BtuR/CobO/CobP - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - CobA_CobO_BtuR SRR21617311_k127_2762903_6 379066.GAU_0585 1.07e-18 94.0 COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf SRR21617311_k127_2762903_4 411463.EUBVEN_00788 6.916e-25 108.0 2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes,251YU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SRR21617311_k127_2762903_3 498761.HM1_3148 8.672e-28 114.0 2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SRR21617311_k127_2762903_5 1131269.AQVV01000018_gene1940 2.347e-20 92.0 2DPX5@1|root,333S8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_9 1304875.JAFZ01000002_gene1 7.462e-13 70.0 2DMHR@1|root,32RMI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_1 1379698.RBG1_1C00001G0917 1.137e-34 136.0 2DMNG@1|root,32SP1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_14 927658.AJUM01000039_gene587 5.593e-07 55.0 2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,2FU6R@200643|Bacteroidia,3XKC9@558415|Marinilabiliaceae 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_2762903_17 411463.EUBVEN_00522 3.95e-05 46.0 2AWWH@1|root,31NU1@2|Bacteria,1TZQE@1239|Firmicutes,24VTK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SRR21617311_k127_2762903_12 880073.Calab_0119 5.282e-11 75.0 2F9BU@1|root,341NU@2|Bacteria,2NR9C@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_8 498761.HM1_3125 3.322e-16 85.0 2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia 186801|Clostridia S ORF located using Blastx - - - - - - - - - - - - - SRR21617311_k127_2762903_11 525255.HMPREF0077_1527 5.704e-12 72.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,25HQ1@186801|Clostridia 186801|Clostridia S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - SRR21617311_k127_2762903_7 211165.AJLN01000021_gene2775 1.225e-16 85.0 2A7FA@1|root,30WCV@2|Bacteria,1GFDD@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_18 72658.Bostr.14018s0001.1.p 4.851e-05 46.0 2E30T@1|root,2SA69@2759|Eukaryota,37XUE@33090|Viridiplantae,3GMF3@35493|Streptophyta 35493|Streptophyta - - - - - - - - - - - - - - - SRR21617311_k127_2762903_10 1150469.RSPPHO_03279 3.676e-12 71.0 2DTV2@1|root,33MS7@2|Bacteria,1NKAB@1224|Proteobacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2762903_2 1304875.JAFZ01000002_gene400 1.368e-34 135.0 2B9ZZ@1|root,323DM@2|Bacteria 2|Bacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - SRR21617311_k127_2767406_0 1121468.AUBR01000004_gene105 1.598e-273 856.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,42EPA@68295|Thermoanaerobacterales 186801|Clostridia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim SRR21617311_k127_2767406_2 1160137.KB907309_gene5979 5.12e-10 64.0 COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae 201174|Actinobacteria S Belongs to the UPF0232 family - - - - - - - - - - - - DUF721 SRR21617311_k127_2767406_1 1379698.RBG1_1C00001G0265 1.286e-107 355.0 COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria 2|Bacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338,ko:K03610 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400,ko04812 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 SRR21617311_k127_2773938_0 1379698.RBG1_1C00001G0582 3.249e-97 343.0 COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - - - - - - - - - - - ASH,Cohesin,FlgD_ig,Peptidase_S74 SRR21617311_k127_2773938_1 1379698.RBG1_1C00001G1194 5.513e-69 265.0 COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - 3.2.1.91 ko:K14194,ko:K19668 ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CHU_C,DUF11,FlgD_ig,PKD,SdrD_B SRR21617311_k127_2773938_3 411473.RUMCAL_02102 0.0006586 51.0 COG3209@1|root,COG3209@2|Bacteria,1V7WC@1239|Firmicutes,24JJX@186801|Clostridia 186801|Clostridia M COG3209 Rhs family protein - - - - - - - - - - - - PG_binding_1,Peptidase_C14 SRR21617311_k127_2773938_2 204669.Acid345_0757 4.334e-12 75.0 COG0457@1|root,COG0457@2|Bacteria,3Y986@57723|Acidobacteria 204669.Acid345_0757|- S Tetratricopeptide repeat - - - - - - - - - - - - - SRR21617311_k127_2774056_6 391038.Bphy_3423 3.784e-20 90.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SRR21617311_k127_2774056_0 1379698.RBG1_1C00001G0128 7.721e-97 323.0 COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria 2|Bacteria L tRNA processing larE - - ko:K06864 - - - - ko00000 - - - ATP_bind_3,Asn_synthase,NAD_synthase,QueC SRR21617311_k127_2774056_1 1379698.RBG1_1C00001G0129 9.791e-70 241.0 COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria 2|Bacteria S Bifunctional nuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03617,ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR SRR21617311_k127_2774056_2 1379698.RBG1_1C00001G0130 1.27e-51 189.0 COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N SRR21617311_k127_2774056_4 1379698.RBG1_1C00001G0131 1.55e-23 101.0 COG0238@1|root,COG0238@2|Bacteria,2NPTU@2323|unclassified Bacteria 2|Bacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 SRR21617311_k127_2774056_5 1499967.BAYZ01000179_gene4640 2.077e-20 95.0 COG0360@1|root,COG0360@2|Bacteria,2NQ1Q@2323|unclassified Bacteria 2|Bacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 SRR21617311_k127_2774056_3 1379698.RBG1_1C00001G0134 1.156e-50 186.0 COG0193@1|root,COG0193@2|Bacteria,2NPQ7@2323|unclassified Bacteria 2|Bacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro SRR21617311_k127_2774056_7 316274.Haur_4277 0.0008302 46.0 COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia 32061|Chloroflexia S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SRR21617311_k127_2782422_0 316067.Geob_1385 3.968e-69 242.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales 28221|Deltaproteobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC SRR21617311_k127_2782422_2 1379698.RBG1_1C00001G1856 7.433e-30 131.0 COG3746@1|root,COG3746@2|Bacteria,2NRQ1@2323|unclassified Bacteria 2|Bacteria P phosphate-selective porin O and P oprP - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_4,Porin_O_P SRR21617311_k127_2782422_1 1379698.RBG1_1C00001G1266 1.313e-47 179.0 COG1525@1|root,COG1525@2|Bacteria,2NQ3M@2323|unclassified Bacteria 2|Bacteria L Staphylococcal nuclease homologues - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - Ada_Zn_binding,SNase SRR21617311_k127_2782422_3 411489.CLOL250_02453 3.49e-12 71.0 COG2801@1|root,COG2801@2|Bacteria,1TSXX@1239|Firmicutes,24C90@186801|Clostridia,36JFR@31979|Clostridiaceae 186801|Clostridia L COG COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_28,rve SRR21617311_k127_2782422_5 1121272.KB903249_gene1924 0.0008503 49.0 COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DATE@85008|Micromonosporales 201174|Actinobacteria L Transposase and inactivated derivatives tnp - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - HTH_23,LZ_Tnp_IS481,rve,rve_3 SRR21617311_k127_2782422_4 1047013.AQSP01000030_gene1751 0.0001643 45.0 COG0399@1|root,COG2801@1|root,COG0399@2|Bacteria,COG2801@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - DegT_DnrJ_EryC1,HTH_32 SRR21617311_k127_278680_2 1379698.RBG1_1C00001G1576 3.86e-82 276.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SRR21617311_k127_278680_8 1379698.RBG1_1C00001G1577 2.388e-46 175.0 COG0200@1|root,COG0200@2|Bacteria,2NPNV@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A SRR21617311_k127_278680_18 309801.trd_0967 8.752e-11 65.0 COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia 189775|Thermomicrobia J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 SRR21617311_k127_278680_7 1379698.RBG1_1C00001G1579 2.718e-54 196.0 COG0098@1|root,COG0098@2|Bacteria,2NPGN@2323|unclassified Bacteria 2|Bacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C SRR21617311_k127_278680_12 1519464.HY22_03295 2.033e-29 121.0 COG0256@1|root,COG0256@2|Bacteria,1FE5N@1090|Chlorobi 1090|Chlorobi J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p SRR21617311_k127_278680_5 1379698.RBG1_1C00001G1581 3.245e-65 227.0 COG0097@1|root,COG0097@2|Bacteria,2NPAS@2323|unclassified Bacteria 2|Bacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 SRR21617311_k127_278680_11 521098.Aaci_2697 6.598e-32 129.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,278BE@186823|Alicyclobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 SRR21617311_k127_278680_14 760568.Desku_3044 3.718e-24 104.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,262RF@186807|Peptococcaceae 186801|Clostridia J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 SRR21617311_k127_278680_3 1379698.RBG1_1C00001G1584 2.326e-76 266.0 COG0094@1|root,COG0094@2|Bacteria,2NP65@2323|unclassified Bacteria 2|Bacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C SRR21617311_k127_278680_13 1121468.AUBR01000044_gene1850 3.538e-29 120.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales 186801|Clostridia J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 SRR21617311_k127_278680_6 1379698.RBG1_1C00001G1586 4.952e-59 206.0 COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria 2|Bacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 SRR21617311_k127_278680_15 648996.Theam_0266 4.687e-21 100.0 COG0186@1|root,COG0186@2|Bacteria,2G49I@200783|Aquificae 200783|Aquificae J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 SRR21617311_k127_278680_17 1379698.RBG1_1C00001G1588 7.962e-14 77.0 COG0255@1|root,COG0255@2|Bacteria,2NQ49@2323|unclassified Bacteria 2|Bacteria J Ribosomal L29 protein rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 SRR21617311_k127_278680_4 1379698.RBG1_1C00001G1589 3.129e-65 232.0 COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria 2|Bacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 SRR21617311_k127_278680_1 1379698.RBG1_1C00001G1590 1.256e-97 330.0 COG0092@1|root,COG0092@2|Bacteria,2NP6J@2323|unclassified Bacteria 2|Bacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C SRR21617311_k127_278680_10 1379698.RBG1_1C00001G1591 1.608e-37 145.0 COG0091@1|root,COG0091@2|Bacteria,2NPNW@2323|unclassified Bacteria 2|Bacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 SRR21617311_k127_278680_9 880073.Calab_2130 3.565e-40 152.0 COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria 2|Bacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 SRR21617311_k127_278680_0 1379698.RBG1_1C00001G1593 9.982e-138 441.0 COG0090@1|root,COG0090@2|Bacteria,2NNR3@2323|unclassified Bacteria 2|Bacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C SRR21617311_k127_278680_16 555088.DealDRAFT_1521 1.034e-18 89.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,42K40@68298|Syntrophomonadaceae 186801|Clostridia J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 SRR21617311_k127_278680_19 1120973.AQXL01000112_gene1074 1.11e-06 51.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,2789A@186823|Alicyclobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 SRR21617311_k127_2788997_1 1379698.RBG1_1C00001G0958 4.492e-19 87.0 COG1561@1|root,COG1561@2|Bacteria,2NPG5@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF1732) yicC - - ko:K03316 - - - - ko00000 2.A.36 - - DUF1732,YicC_N SRR21617311_k127_2788997_0 1158318.ATXC01000002_gene1464 4.345e-45 170.0 COG0194@1|root,COG0194@2|Bacteria,2G3ZQ@200783|Aquificae 200783|Aquificae F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin SRR21617311_k127_2793346_1 671143.DAMO_0100 2.756e-136 448.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system atoC - - ko:K02481,ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_2793346_3 671143.DAMO_0099 4.309e-73 267.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - 4HB_MCP_1,HAMP,HATPase_c,HisKA,TarH SRR21617311_k127_2793346_2 1125863.JAFN01000001_gene322 2.446e-84 290.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR21617311_k127_2793346_0 1379698.RBG1_1C00001G1654 5.461e-265 823.0 COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria 2|Bacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SRR21617311_k127_2793346_4 1379698.RBG1_1C00001G0331 5.594e-73 257.0 COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein porQ - - - - - - - - - - - PorP_SprF SRR21617311_k127_2793346_6 1379698.RBG1_1C00001G0332 2.247e-07 53.0 COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 LptE SRR21617311_k127_2800540_0 697303.Thewi_0235 8.383e-84 285.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,24DS0@186801|Clostridia 186801|Clostridia S Peptidoglycan binding - - - - - - - - - - - - DUF1028,PG_binding_2 SRR21617311_k127_2805043_0 1379698.RBG1_1C00001G0820 9.062e-156 499.0 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SRR21617311_k127_2805043_1 316274.Haur_4656 1.207e-05 57.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia 32061|Chloroflexia T SMART PAS domain containing protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4 SRR21617311_k127_2805447_4 945713.IALB_0461 5.904e-11 68.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family aprN - - - - - - - - - - - Peptidase_S8 SRR21617311_k127_2805447_0 756067.MicvaDRAFT_5451 1.085e-131 449.0 COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales 1117|Cyanobacteria MQ PFAM Collagen-binding surface protein Cna-like, B-type domain - - - - - - - - - - - - DUF4347,HemolysinCabind,SdrD_B SRR21617311_k127_2805447_2 1379698.RBG1_1C00001G1831 9.449e-72 269.0 COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria 2|Bacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - PKD,VCBS SRR21617311_k127_2805447_3 103372.F4X1C1 1.142e-11 78.0 KOG3637@1|root,KOG3637@2759|Eukaryota,38CFX@33154|Opisthokonta,3B96W@33208|Metazoa,3CUDX@33213|Bilateria,41VRB@6656|Arthropoda,3SGM1@50557|Insecta,46HSR@7399|Hymenoptera 33208|Metazoa W Integrin alpha ITGAV GO:0000003,GO:0000165,GO:0000302,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001655,GO:0001656,GO:0001667,GO:0001701,GO:0001704,GO:0001706,GO:0001707,GO:0001708,GO:0001726,GO:0001775,GO:0001816,GO:0001822,GO:0001890,GO:0001892,GO:0001894,GO:0001932,GO:0001934,GO:0001944,GO:0001968,GO:0002009,GO:0002011,GO:0002020,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002165,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002474,GO:0002478,GO:0002479,GO:0002520,GO:0002790,GO:0003006,GO:0003008,GO:0003674,GO:0004888,GO:0005102,GO:0005126,GO:0005154,GO:0005161,GO:0005172,GO:0005178,GO:0005215,GO:0005216,GO:0005244,GO:0005245,GO:0005261,GO:0005262,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0005902,GO:0005912,GO:0005924,GO:0005925,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006887,GO:0006897,GO:0006909,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0006996,GO:0007010,GO:0007044,GO:0007045,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007160,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007204,GO:0007229,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007414,GO:0007417,GO:0007419,GO:0007423,GO:0007424,GO:0007426,GO:0007427,GO:0007431,GO:0007435,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007492,GO:0007494,GO:0007498,GO:0007517,GO:0007548,GO:0007552,GO:0007560,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007611,GO:0007613,GO:0008037,GO:0008038,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008305,GO:0008324,GO:0008406,GO:0008587,GO:0009306,GO:0009566,GO:0009593,GO:0009595,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009925,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010628,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010669,GO:0010743,GO:0010745,GO:0010810,GO:0010811,GO:0010869,GO:0010871,GO:0010883,GO:0010888,GO:0010927,GO:0010941,GO:0012501,GO:0012505,GO:0012506,GO:0014069,GO:0015026,GO:0015031,GO:0015075,GO:0015085,GO:0015267,GO:0015318,GO:0015833,GO:0016020,GO:0016021,GO:0016032,GO:0016043,GO:0016192,GO:0016203,GO:0016310,GO:0016323,GO:0016477,GO:0017015,GO:0019058,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019838,GO:0019882,GO:0019884,GO:0019899,GO:0019953,GO:0019955,GO:0021551,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022610,GO:0022612,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030097,GO:0030100,GO:0030139,GO:0030141,GO:0030154,GO:0030155,GO:0030175,GO:0030182,GO:0030198,GO:0030239,GO:0030260,GO:0030334,GO:0030335,GO:0030425,GO:0030511,GO:0030659,GO:0030667,GO:0030707,GO:0030855,GO:0030947,GO:0030949,GO:0031032,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031253,GO:0031256,GO:0031258,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031430,GO:0031527,GO:0031528,GO:0031589,GO:0031672,GO:0031982,GO:0032231,GO:0032268,GO:0032270,GO:0032279,GO:0032368,GO:0032369,GO:0032490,GO:0032501,GO:0032502,GO:0032504,GO:0032587,GO:0032589,GO:0032590,GO:0032591,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033218,GO:0033627,GO:0033631,GO:0033688,GO:0033690,GO:0034103,GO:0034113,GO:0034220,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0034446,GO:0034678,GO:0034683,GO:0034684,GO:0034685,GO:0034686,GO:0035099,GO:0035107,GO:0035114,GO:0035120,GO:0035152,GO:0035160,GO:0035162,GO:0035220,GO:0035239,GO:0035262,GO:0035272,GO:0035295,GO:0035313,GO:0035556,GO:0035579,GO:0035821,GO:0035866,GO:0035867,GO:0035868,GO:0035987,GO:0036211,GO:0036230,GO:0036477,GO:0038023,GO:0038027,GO:0038034,GO:0038044,GO:0040011,GO:0040012,GO:0040017,GO:0040025,GO:0040028,GO:0042058,GO:0042059,GO:0042060,GO:0042110,GO:0042119,GO:0042127,GO:0042221,GO:0042277,GO:0042325,GO:0042327,GO:0042330,GO:0042383,GO:0042471,GO:0042472,GO:0042493,GO:0042581,GO:0042590,GO:0042592,GO:0042692,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043184,GO:0043197,GO:0043204,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043235,GO:0043277,GO:0043292,GO:0043299,GO:0043312,GO:0043408,GO:0043410,GO:0043412,GO:0043542,GO:0043583,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044309,GO:0044319,GO:0044403,GO:0044409,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045055,GO:0045124,GO:0045137,GO:0045165,GO:0045177,GO:0045178,GO:0045184,GO:0045185,GO:0045202,GO:0045214,GO:0045216,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045714,GO:0045715,GO:0045765,GO:0045766,GO:0045785,GO:0045807,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0046649,GO:0046718,GO:0046850,GO:0046873,GO:0046903,GO:0046982,GO:0046983,GO:0048002,GO:0048010,GO:0048041,GO:0048332,GO:0048333,GO:0048468,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048562,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048745,GO:0048812,GO:0048839,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0048878,GO:0050431,GO:0050663,GO:0050730,GO:0050731,GO:0050746,GO:0050748,GO:0050764,GO:0050766,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050839,GO:0050840,GO:0050877,GO:0050890,GO:0050896,GO:0050900,GO:0050919,GO:0051049,GO:0051050,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051145,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051209,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051270,GO:0051272,GO:0051282,GO:0051283,GO:0051480,GO:0051492,GO:0051493,GO:0051606,GO:0051641,GO:0051649,GO:0051674,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051817,GO:0051828,GO:0052066,GO:0052190,GO:0052191,GO:0052231,GO:0052370,GO:0052522,GO:0055001,GO:0055002,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0055120,GO:0055123,GO:0060089,GO:0060099,GO:0060100,GO:0060249,GO:0060255,GO:0060401,GO:0060402,GO:0060429,GO:0060537,GO:0060538,GO:0060541,GO:0060548,GO:0060562,GO:0060627,GO:0060706,GO:0060707,GO:0061061,GO:0061062,GO:0061458,GO:0061564,GO:0065007,GO:0065008,GO:0070161,GO:0070371,GO:0070588,GO:0070838,GO:0070851,GO:0070925,GO:0071062,GO:0071702,GO:0071704,GO:0071705,GO:0071731,GO:0071840,GO:0071944,GO:0072001,GO:0072325,GO:0072327,GO:0072358,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0080090,GO:0090092,GO:0090100,GO:0090130,GO:0090132,GO:0090287,GO:0090504,GO:0090505,GO:0090596,GO:0097060,GO:0097190,GO:0097191,GO:0097192,GO:0097366,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097553,GO:0097708,GO:0098552,GO:0098581,GO:0098588,GO:0098590,GO:0098609,GO:0098636,GO:0098655,GO:0098657,GO:0098660,GO:0098662,GO:0098742,GO:0098771,GO:0098794,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0098858,GO:0098984,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099572,GO:0110020,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1901074,GO:1901076,GO:1901184,GO:1901185,GO:1901342,GO:1901564,GO:1901698,GO:1901700,GO:1902531,GO:1902533,GO:1902680,GO:1902903,GO:1903506,GO:1903508,GO:1903670,GO:1903672,GO:1903844,GO:1903846,GO:1904018,GO:1905153,GO:1905155,GO:1905952,GO:1905953,GO:1990430,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000209,GO:2000425,GO:2000427,GO:2000535,GO:2000536,GO:2000721,GO:2000811,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237 - ko:K06484,ko:K06487,ko:K06584 ko04145,ko04151,ko04510,ko04512,ko04514,ko04640,ko04810,ko04919,ko05100,ko05131,ko05133,ko05165,ko05200,ko05205,ko05206,ko05222,ko05410,ko05412,ko05414,ko05418,map04145,map04151,map04510,map04512,map04514,map04640,map04810,map04919,map05100,map05131,map05133,map05165,map05200,map05205,map05206,map05222,map05410,map05412,map05414,map05418 - - - ko00000,ko00001,ko04090,ko04131,ko04147,ko04516 - - - FG-GAP,Integrin_alpha,Integrin_alpha2 SRR21617311_k127_2805447_1 886293.Sinac_4765 1.616e-102 352.0 COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes 203682|Planctomycetes U Pkd domain containing protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - - SRR21617311_k127_2815078_3 1379698.RBG1_1C00001G0116 1.847e-72 251.0 2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2815078_1 1379698.RBG1_1C00001G0117 2.168e-92 312.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2815078_2 1379698.RBG1_1C00001G0118 1.433e-81 276.0 29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2815078_0 1379698.RBG1_1C00001G0119 8.929e-135 441.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SRR21617311_k127_2824672_0 1379698.RBG1_1C00001G0625 1.784e-187 603.0 COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria 2|Bacteria S Vault protein inter-alpha-trypsin domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - FecR,VIT,VWA,VWA_3 SRR21617311_k127_2824672_2 1379270.AUXF01000001_gene2333 4.147e-31 124.0 COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes 142182|Gemmatimonadetes B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB SRR21617311_k127_2824672_3 314256.OG2516_10044 1.283e-11 72.0 COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria,2PDTT@252301|Oceanicola 28211|Alphaproteobacteria N Flagellar basal body rod FlgEFG protein C-terminal flgF - - ko:K02391,ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C SRR21617311_k127_2824672_1 1379698.RBG1_1C00001G0745 8.678e-65 231.0 COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 SRR21617311_k127_2826394_5 1047013.AQSP01000114_gene683 2.836e-21 93.0 COG0286@1|root,COG0286@2|Bacteria,2NQG4@2323|unclassified Bacteria 2|Bacteria V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase SRR21617311_k127_2826394_3 1173027.Mic7113_1696 1.444e-39 150.0 COG2852@1|root,COG2852@2|Bacteria,1G6T3@1117|Cyanobacteria,1HBZY@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF559) - - - - - - - - - - - - DUF559 SRR21617311_k127_2826394_0 1379698.RBG1_1C00001G0427 7.644e-168 541.0 COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria 2|Bacteria L MgsA AAA+ ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N SRR21617311_k127_2826394_1 1379698.RBG1_1C00001G0220 9.37e-118 396.0 COG3292@1|root,COG3292@2|Bacteria,2NR5N@2323|unclassified Bacteria 2|Bacteria T Two component regulator propeller - - - ko:K19693 - - - - ko00000,ko03000 - - - HATPase_c,HTH_18,HisKA,Response_reg SRR21617311_k127_2826394_2 1379698.RBG1_1C00001G0219 1.979e-76 267.0 COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria 2|Bacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946,ko:K07123 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2977c,iSFV_1184.SFV_0382,iYO844.BSU05900 AIRS,AIRS_C SRR21617311_k127_2826394_4 374847.Kcr_0583 1.016e-23 106.0 COG2193@1|root,arCOG01094@2157|Archaea 2157|Archaea P Ferritin-like domain bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin SRR21617311_k127_2826405_2 479434.Sthe_1281 1.916e-09 66.0 COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia 189775|Thermomicrobia S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 SRR21617311_k127_2826405_0 1379698.RBG1_1C00001G1142 3.791e-102 340.0 COG0616@1|root,COG0616@2|Bacteria,2NPIE@2323|unclassified Bacteria 2|Bacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 SRR21617311_k127_2826405_1 180281.CPCC7001_398 3.21e-19 93.0 COG1388@1|root,COG1388@2|Bacteria,1GM7W@1117|Cyanobacteria,22SWZ@167375|Cyanobium 1117|Cyanobacteria M Lysin motif - - - - - - - - - - - - LysM SRR21617311_k127_2829904_2 1379698.RBG1_1C00001G1327 2.25e-57 202.0 COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family ubiA - - - - - - - - - - - UbiA SRR21617311_k127_2829904_0 1379698.RBG1_1C00001G0533 2.344e-137 446.0 COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria 2|Bacteria K acetyltransferase yghO - - - - - - - - - - - Acetyltransf_1 SRR21617311_k127_2829904_1 1379698.RBG1_1C00001G0532 8.443e-122 394.0 COG0156@1|root,COG0156@2|Bacteria,2NNMX@2323|unclassified Bacteria 2|Bacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_2832378_1 479434.Sthe_2120 4.615e-37 142.0 COG0309@1|root,COG0309@2|Bacteria,2G7TM@200795|Chloroflexi,27XK5@189775|Thermomicrobia 189775|Thermomicrobia O AIR synthase related protein, C-terminal domain - - - - - - - - - - - - AIRS,AIRS_C SRR21617311_k127_2832378_0 1232410.KI421416_gene2561 3.525e-65 232.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 SRR21617311_k127_2832378_2 1379698.RBG1_1C00001G1201 1.836e-11 68.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase crtF - - - - - - - - - - - Methyltransf_11,Methyltransf_2,Methyltransf_23 SRR21617311_k127_2835346_2 926569.ANT_03070 7.846e-06 57.0 COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi 200795|Chloroflexi UW Hep Hag repeat protein - - - - - - - - - - - - - SRR21617311_k127_2835346_1 1379698.RBG1_1C00001G0282 2.898e-37 154.0 COG5276@1|root,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria 2|Bacteria M Hep Hag repeat protein - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Calx-beta,LVIVD SRR21617311_k127_2835346_0 1047013.AQSP01000112_gene393 1.14e-105 360.0 COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria 2|Bacteria M Bacterial sugar transferase cpsE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Bac_transf,CoA_binding_3,STAS SRR21617311_k127_2837993_0 1379698.RBG1_1C00001G0871 1.693e-159 513.0 COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SRR21617311_k127_2840406_0 1379698.RBG1_1C00001G1479 1.025e-193 612.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria 2|Bacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO SRR21617311_k127_2843205_6 266117.Rxyl_1332 1.642e-08 64.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator - - - ko:K01420,ko:K10914,ko:K21561,ko:K21564 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding SRR21617311_k127_2843205_4 1379698.RBG1_1C00001G1088 9.148e-103 350.0 COG0320@1|root,COG0320@2|Bacteria,2NNPI@2323|unclassified Bacteria 2|Bacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Lip_prot_lig_C,Radical_SAM SRR21617311_k127_2843205_5 1134413.ANNK01000040_gene1335 1.725e-102 342.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SRR21617311_k127_2843205_0 1379698.RBG1_1C00001G0688 5.934e-298 923.0 COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS SRR21617311_k127_2843205_1 1379698.RBG1_1C00001G0687 3.201e-145 473.0 COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria 2|Bacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III glmM - 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SRR21617311_k127_2843205_3 1123371.ATXH01000015_gene1672 1.28e-112 378.0 COG1030@1|root,COG1030@2|Bacteria,2GH7J@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD SRR21617311_k127_2843205_2 1379698.RBG1_1C00001G1759 8.702e-120 389.0 COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria 2|Bacteria O prohibitin homologues hflC - - - - - - - - - - - Band_7 SRR21617311_k127_2843273_4 1379698.RBG1_1C00001G1613 2.427e-66 235.0 COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria 2|Bacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,PEGA,Pkinase SRR21617311_k127_2843273_3 1379698.RBG1_1C00001G0237 3.346e-78 280.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Calx-beta,LVIVD SRR21617311_k127_2843273_0 1379698.RBG1_1C00001G0278 0.0 1221.0 COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria 2|Bacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SRR21617311_k127_2843273_7 216591.BCAL3319 4.71e-09 64.0 COG3832@1|root,COG3832@2|Bacteria,1RDXJ@1224|Proteobacteria,2WFS3@28216|Betaproteobacteria,1KI5A@119060|Burkholderiaceae 28216|Betaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SRR21617311_k127_2843273_1 123214.PERMA_1630 6.052e-114 376.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd SRR21617311_k127_2843273_2 1379698.RBG1_1C00001G1203 1.439e-79 273.0 COG1208@1|root,COG1208@2|Bacteria,2NPHW@2323|unclassified Bacteria 2|Bacteria JM Nucleotidyl transferase mpg2 - 2.7.7.13 ko:K00966,ko:K21210 ko00051,ko00520,ko01059,ko01100,ko01110,ko01130,map00051,map00520,map01059,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R11429 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SRR21617311_k127_2843273_5 326427.Cagg_0564 9.978e-21 101.0 COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia 32061|Chloroflexia S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SRR21617311_k127_2843663_1 1379698.RBG1_1C00001G0601 3.676e-72 252.0 COG0842@1|root,COG0842@2|Bacteria,2NQYW@2323|unclassified Bacteria 2|Bacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SRR21617311_k127_2843663_0 443143.GM18_4024 1.79e-87 295.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,43UYD@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 SRR21617311_k127_2843663_2 596152.DesU5LDRAFT_2125 2.317e-24 110.0 COG1988@1|root,COG1988@2|Bacteria,1N7RW@1224|Proteobacteria,42WGG@68525|delta/epsilon subdivisions,2WSG3@28221|Deltaproteobacteria,2MFXP@213115|Desulfovibrionales 28221|Deltaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM SRR21617311_k127_2858195_3 153948.NAL212_3132 1.378e-11 74.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,371VE@32003|Nitrosomonadales 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SRR21617311_k127_2858195_0 1379698.RBG1_1C00001G1524 4.473e-205 680.0 COG2911@1|root,COG2911@2|Bacteria,2NQ89@2323|unclassified Bacteria 2|Bacteria S TamB, inner membrane protein subunit of TAM complex - - - ko:K07277,ko:K09800 - - - - ko00000,ko02000,ko03029 1.B.33 - - AsmA_2,DUF748,TamB SRR21617311_k127_2858195_1 1203554.HMPREF1476_02365 8.096e-40 165.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4PQJ7@995019|Sutterellaceae 28216|Betaproteobacteria M Trypsin mucD - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR21617311_k127_2858195_2 880073.Calab_0781 1.542e-37 147.0 COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria 2|Bacteria K TIGRFAM RNA polymerase sigma factor, sigma-70 family sigG - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_2872518_0 1379698.RBG1_1C00001G1816 6.328e-87 299.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - DUF2723,PMT_2,TPR_8 SRR21617311_k127_2872518_1 479431.Namu_2374 2.986e-72 275.0 COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4EUZ4@85013|Frankiales 201174|Actinobacteria S Immune inhibitor A peptidase M6 - - - - - - - - - - - - Peptidase_M6 SRR21617311_k127_2872518_2 1121403.AUCV01000003_gene1860 3.971e-68 240.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MIJ9@213118|Desulfobacterales 28221|Deltaproteobacteria KT Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat SRR21617311_k127_2874720_0 1122603.ATVI01000006_gene7 2.325e-114 375.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales 135614|Xanthomonadales G Dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH SRR21617311_k127_2874720_1 1380394.JADL01000009_gene3305 2.887e-78 263.0 COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TUKD@28211|Alphaproteobacteria,2JRK5@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 SRR21617311_k127_2875920_1 350688.Clos_2332 2.925e-52 192.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,36FQU@31979|Clostridiaceae 186801|Clostridia I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase SRR21617311_k127_2875920_0 1121121.KB894307_gene2049 1.312e-77 273.0 COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli 91061|Bacilli I Protein of unknown function (DUF3419) - - - ko:K13622 ko00564,map00564 - R09072 RC00021,RC01091 ko00000,ko00001 - - - DUF3419 SRR21617311_k127_2875920_2 56110.Oscil6304_1395 1.936e-46 179.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_2879538_0 204669.Acid345_4501 1.112e-119 400.0 COG1228@1|root,COG1228@2|Bacteria,3Y6Y2@57723|Acidobacteria,2JK82@204432|Acidobacteriia 204432|Acidobacteriia Q Amidohydrolase family - - - - - - - - - - - - - SRR21617311_k127_2879538_3 224911.27354539 6.96e-19 93.0 COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U5Y2@28211|Alphaproteobacteria,3JY31@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 SRR21617311_k127_2879538_1 204669.Acid345_4500 2.396e-96 331.0 COG1228@1|root,COG1228@2|Bacteria,3Y69U@57723|Acidobacteria,2JMB0@204432|Acidobacteriia 204432|Acidobacteriia Q Amidohydrolase family - - - - - - - - - - - - - SRR21617311_k127_2879538_2 370438.PTH_1977 5.062e-19 92.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae 186801|Clostridia L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SRR21617311_k127_2888192_1 1033734.CAET01000049_gene1620 1.757e-129 429.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N SRR21617311_k127_2888192_0 1379698.RBG1_1C00001G0935 1.787e-212 671.0 COG0422@1|root,COG0422@2|Bacteria,2NNV7@2323|unclassified Bacteria 2|Bacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c45100,iYO844.BSU08790 ThiC-associated,ThiC_Rad_SAM SRR21617311_k127_2888192_3 556261.HMPREF0240_04300 3.565e-25 117.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25F0H@186801|Clostridia,36UU5@31979|Clostridiaceae 186801|Clostridia H Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2888192_4 1134413.ANNK01000031_gene1427 4.971e-06 55.0 COG0438@1|root,COG0438@2|Bacteria,1UXEH@1239|Firmicutes,4HATX@91061|Bacilli,1ZEKD@1386|Bacillus 91061|Bacilli M Glycosyltransferase Family 4 - - - ko:K16697 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_2888192_2 1379698.RBG1_1C00001G0937 2.057e-88 296.0 COG1635@1|root,COG1635@2|Bacteria,2NR92@2323|unclassified Bacteria 2|Bacteria H Thi4 family thi4 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K03146 ko00730,ko01100,map00730,map01100 - R10685 RC00033,RC03253,RC03254 ko00000,ko00001 - - - FAD_oxidored,Thi4 SRR21617311_k127_2890606_0 1379698.RBG1_1C00001G1558 9.067e-74 253.0 COG1974@1|root,COG1974@2|Bacteria,2NPJG@2323|unclassified Bacteria 2|Bacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SRR21617311_k127_2890606_1 1379698.RBG1_1C00001G1369 7.02e-55 201.0 COG4219@1|root,COG4219@2|Bacteria,2NR11@2323|unclassified Bacteria 2|Bacteria KT Peptidase M56 - - - - - - - - - - - - Amidase_6,DUF4309,DUF5301 SRR21617311_k127_290256_6 1254432.SCE1572_15335 4.351e-21 99.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales 28221|Deltaproteobacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_290256_7 338969.Rfer_2737 6.533e-18 87.0 COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria 1224|Proteobacteria T Pfam Response regulator receiver - - - - - - - - - - - - Response_reg SRR21617311_k127_290256_5 880073.Calab_0921 1.466e-25 123.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 SRR21617311_k127_290256_4 543734.LCABL_29620 5.032e-35 138.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc SRR21617311_k127_290256_0 1379698.RBG1_1C00001G0297 3.346e-156 504.0 COG4881@1|root,COG4881@2|Bacteria 2|Bacteria - - cbcU - - - - - - - - - - - NrfD SRR21617311_k127_290256_1 1379698.RBG1_1C00001G0296 2.208e-95 318.0 COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S binding domain ttrB - - ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Fer4_11,Fer4_3,Fer4_7 SRR21617311_k127_290256_3 1379698.RBG1_1C00001G0295 8.209e-64 226.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - ko:K04013,ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_C552,Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1 SRR21617311_k127_290256_2 634498.mru_1002 1.9e-66 230.0 COG0477@1|root,arCOG02682@2157|Archaea,2XWP6@28890|Euryarchaeota,23PB6@183925|Methanobacteria 183925|Methanobacteria G Sugar (and other) transporter - - - - - - - - - - - - - SRR21617311_k127_2902913_2 1191523.MROS_0058 2.866e-32 142.0 COG2372@1|root,COG2372@2|Bacteria 2|Bacteria C response to copper ion - - - ko:K07156 - - - - ko00000,ko02000 9.B.62.2 - - Big_5,DUF4082,SLH SRR21617311_k127_2902913_3 1278073.MYSTI_00326 0.0001372 55.0 COG2319@1|root,COG2319@2|Bacteria 2|Bacteria S anaphase-promoting complex binding - - - - - - - - - - - - Beta_helix,Big_5,DUF4082,F5_F8_type_C,Glyco_hydro_81,KAP_NTPase,WD40 SRR21617311_k127_2902913_0 1379698.RBG1_1C00001G1335 1.688e-48 199.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - - SRR21617311_k127_2902913_1 1379698.RBG1_1C00001G1334 1.688e-42 168.0 COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria 2|Bacteria I Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SRR21617311_k127_2905100_0 1379698.RBG1_1C00001G1263 6.655e-102 347.0 COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria 2|Bacteria O Subtilase family aprN - - - - - - - - - - - Peptidase_S8 SRR21617311_k127_2905100_2 861299.J421_3537 8.879e-18 96.0 COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 SRR21617311_k127_2905100_1 1379698.RBG1_1C00001G1504 1.54e-88 304.0 COG0006@1|root,COG0006@2|Bacteria,2NP41@2323|unclassified Bacteria 2|Bacteria E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 SRR21617311_k127_292023_2 1379698.RBG1_1C00001G0226 2.122e-28 121.0 COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 SRR21617311_k127_292023_1 1379698.RBG1_1C00001G0227 2.5e-40 159.0 COG1708@1|root,COG1708@2|Bacteria,2NRPC@2323|unclassified Bacteria 2|Bacteria S nucleotidyltransferase activity - - - - - - - - - - - - KNTase_C,NTP_transf_2 SRR21617311_k127_292023_0 1379698.RBG1_1C00001G0228 2.522e-84 286.0 COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria 2|Bacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 SRR21617311_k127_2921080_3 179408.Osc7112_5435 3.763e-36 141.0 COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria 1117|Cyanobacteria P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 SRR21617311_k127_2921080_0 1157490.EL26_09005 1.118e-172 548.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,2785R@186823|Alicyclobacillaceae 91061|Bacilli Q homogentisate 1,2-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA SRR21617311_k127_2921080_2 358681.BBR47_40870 3.709e-109 361.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,26UR6@186822|Paenibacillaceae 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase SRR21617311_k127_2921080_1 1267533.KB906735_gene4693 6.186e-128 413.0 COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia 204432|Acidobacteriia E Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase SRR21617311_k127_2924749_10 1379698.RBG1_1C00001G0457 2.563e-52 188.0 COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria 2|Bacteria S (Rhomboid) family GlpG - - ko:K07059 - - - - ko00000 - - - Rhomboid SRR21617311_k127_2924749_2 1379698.RBG1_1C00001G1802 1.73e-192 608.0 COG0538@1|root,COG0538@2|Bacteria,2NS4M@2323|unclassified Bacteria 2|Bacteria C Isocitrate/isopropylmalate dehydrogenase icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Iso_dh SRR21617311_k127_2924749_13 289376.THEYE_A0330 2.286e-39 158.0 COG1463@1|root,COG1463@2|Bacteria,3J164@40117|Nitrospirae 40117|Nitrospirae Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SRR21617311_k127_2924749_7 1009370.ALO_15777 7.302e-59 219.0 COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes 909932|Negativicutes Q ABC transporter, ATP-binding protein ttg2A - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SRR21617311_k127_2924749_9 316067.Geob_1939 6.287e-58 210.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,43B0R@68525|delta/epsilon subdivisions,2X6ET@28221|Deltaproteobacteria,43TJD@69541|Desulfuromonadales 28221|Deltaproteobacteria P Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE SRR21617311_k127_2924749_12 880073.Calab_0150 3.021e-51 195.0 COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria 2|Bacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat SRR21617311_k127_2924749_14 1379698.RBG1_1C00001G0229 5.215e-31 128.0 2BIY5@1|root,32D6E@2|Bacteria,2NRW7@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_2924749_5 645991.Sgly_0958 1.011e-90 309.0 COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,261W0@186807|Peptococcaceae 186801|Clostridia E PFAM Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP SRR21617311_k127_2924749_1 1379698.RBG1_1C00001G0248 4.184e-218 683.0 COG3391@1|root,COG3391@2|Bacteria,2NQ4U@2323|unclassified Bacteria 2|Bacteria S 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56,SHD1 SRR21617311_k127_2924749_4 1379698.RBG1_1C00001G0708 1.18e-107 356.0 COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria 2|Bacteria E Arginase family speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase SRR21617311_k127_2924749_8 1379698.RBG1_1C00001G0707 4.004e-58 219.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 2|Bacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 - GT51 - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SRR21617311_k127_2924749_0 1379698.RBG1_1C00001G0707 1.669e-257 811.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 2|Bacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 - GT51 - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SRR21617311_k127_2924749_16 1196029.ALIM01000032_gene1373 1.563e-10 74.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C SRR21617311_k127_2924749_15 1410653.JHVC01000012_gene2315 3.876e-15 89.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,36G5K@31979|Clostridiaceae 186801|Clostridia M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K03769,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3 SRR21617311_k127_2924749_3 1379698.RBG1_1C00001G0705 1.544e-125 417.0 COG0760@1|root,COG0760@2|Bacteria,2NPFB@2323|unclassified Bacteria 2|Bacteria O PPIC-type PPIASE domain surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N_3 SRR21617311_k127_2924749_11 234267.Acid_6893 2.805e-52 194.0 COG1388@1|root,COG1388@2|Bacteria,3Y4VG@57723|Acidobacteria 57723|Acidobacteria M Domain of Unknown Function (DUF1259) - - - - - - - - - - - - DUF1529 SRR21617311_k127_2928594_2 1379698.RBG1_1C00001G0593 7.095e-33 132.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,Cadherin_3,DUF11,FlgD_ig SRR21617311_k127_2928594_0 1379698.RBG1_1C00001G0595 1.258e-134 455.0 COG1874@1|root,COG1874@2|Bacteria,2NRR5@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolases family 35 - - 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Sulfotransfer_2 SRR21617311_k127_2928594_3 1144275.COCOR_03995 2.216e-08 66.0 COG1664@1|root,COG4796@1|root,COG1664@2|Bacteria,COG4796@2|Bacteria,1MUS9@1224|Proteobacteria,43BNZ@68525|delta/epsilon subdivisions,2X70B@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - - SRR21617311_k127_2928594_4 1380354.JIAN01000009_gene3812 6.167e-05 55.0 COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,4F2CN@85016|Cellulomonadaceae 201174|Actinobacteria S Putative adhesin - - - - - - - - - - - - DUF4097 SRR21617311_k127_2928594_1 1379698.RBG1_1C00001G1704 1.078e-65 231.0 COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria 2|Bacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR21617311_k127_2941553_0 1379698.RBG1_1C00001G1305 8.463e-226 706.0 COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain actB - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molybdop_Fe4S4,Molydop_binding SRR21617311_k127_2941553_1 1379698.RBG1_1C00001G1304 4.762e-218 687.0 COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria 2|Bacteria C Polysulphide reductase, NrfD actC - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD SRR21617311_k127_2941553_2 1379698.RBG1_1C00001G1303 1.609e-62 220.0 COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria 2|Bacteria C Protein of unknown function (DUF3341) actD - - - - - - - - - - - DUF3341 SRR21617311_k127_2941553_3 264462.Bd1611 9.251e-25 109.0 COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,42XMG@68525|delta/epsilon subdivisions,2MTWQ@213481|Bdellovibrionales,2WSJM@28221|Deltaproteobacteria 213481|Bdellovibrionales C cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 SRR21617311_k127_2942406_3 926550.CLDAP_07830 3.991e-80 290.0 COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi 200795|Chloroflexi G glycosyl hydrolase, BNR repeat-containing protein - - - - - - - - - - - - Sortilin-Vps10 SRR21617311_k127_2942406_2 740709.A10D4_05217 2.046e-92 317.0 COG0769@1|root,COG0769@2|Bacteria,1QYFB@1224|Proteobacteria,1T3Q5@1236|Gammaproteobacteria,2QGQ5@267893|Idiomarinaceae 1236|Gammaproteobacteria M Mur ligase middle domain - - - ko:K01932 - - - - ko00000,ko01000 - - - Mur_ligase_M SRR21617311_k127_2942406_6 459349.CLOAM0865 4.441e-36 142.0 29EG8@1|root,334DW@2|Bacteria,2NPTE@2323|unclassified Bacteria 2|Bacteria S Capsule biosynthesis CapC capC - - ko:K22116 - - - - ko00000 - - - Caps_synth_CapC SRR21617311_k127_2942406_5 459349.CLOAM0866 8.316e-60 227.0 28JNG@1|root,2Z9ES@2|Bacteria,2NPDF@2323|unclassified Bacteria 2|Bacteria - - pgsW - - - - - - - - - - - - SRR21617311_k127_2942406_0 1379698.RBG1_1C00001G0892 1.23e-188 596.0 COG1062@1|root,COG1062@2|Bacteria 2|Bacteria C S-(hydroxymethyl)glutathione dehydrogenase activity - - - - - - - - - - - - ADH_N SRR21617311_k127_2942406_4 1379698.RBG1_1C00001G0893 1.827e-78 267.0 COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria 2|Bacteria K Bacterial regulatory proteins, tetR family - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N SRR21617311_k127_2942406_1 1379698.RBG1_1C00001G0894 2.491e-172 544.0 COG1775@1|root,COG1775@2|Bacteria,2NRF8@2323|unclassified Bacteria 2|Bacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D SRR21617311_k127_2942443_0 1379698.RBG1_1C00001G0712 1.081e-154 502.0 COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_2942443_1 195522.BD01_0726 1.178e-05 51.0 COG0515@1|root,COG3889@1|root,arCOG03264@1|root,arCOG01672@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2Y2TW@28890|Euryarchaeota,243EY@183968|Thermococci 183968|Thermococci E solute binding protein - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SRR21617311_k127_2951605_0 945713.IALB_2995 3.757e-31 139.0 COG4288@1|root,COG4288@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Amidase_2,Big_5,CHU_C,FlgD_ig,LTD SRR21617311_k127_2951605_2 517418.Ctha_2258 1.998e-07 55.0 COG4288@1|root,COG4288@2|Bacteria,1FE3D@1090|Chlorobi 1090|Chlorobi S Lamin Tail Domain - - - - - - - - - - - - CHU_C,FlgD_ig,LTD SRR21617311_k127_2951605_1 1089550.ATTH01000001_gene1676 1.684e-11 74.0 COG1555@1|root,COG1555@2|Bacteria,4NVH1@976|Bacteroidetes,1FJFW@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L photosystem II stabilization - - - - - - - - - - - - - SRR21617311_k127_296280_4 1121957.ATVL01000003_gene2428 6.814e-10 60.0 COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NT8Z@976|Bacteroidetes,47UGR@768503|Cytophagia 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - IgGFc_binding SRR21617311_k127_296280_3 1379698.RBG1_1C00001G0356 6.701e-45 173.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria 2|Bacteria EG Protein of unknown function (DUF2723) - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT SRR21617311_k127_296280_1 1047013.AQSP01000084_gene763 1.812e-78 278.0 COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SRR21617311_k127_296280_2 243365.CV_0843 6.259e-49 186.0 2E06J@1|root,32VUI@2|Bacteria,1NVM1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_296280_0 1047013.AQSP01000142_gene165 1.848e-286 895.0 COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria 2|Bacteria E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 SRR21617311_k127_296280_5 1008457.BAEX01000054_gene638 2.09e-07 54.0 COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,47HBR@76831|Myroides 976|Bacteroidetes I UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD lpxD1 - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD SRR21617311_k127_302621_1 693661.Arcve_1836 7.841e-50 189.0 COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,245VV@183980|Archaeoglobi 183980|Archaeoglobi H UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD SRR21617311_k127_302621_0 1123325.JHUV01000012_gene1032 4.644e-125 411.0 COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae 200783|Aquificae H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate mqnE - 2.5.1.120 ko:K18285 ko00130,ko01110,map00130,map01110 - R10667 RC00021,RC03234 ko00000,ko00001,ko01000 - - - Fer4_14,Radical_SAM SRR21617311_k127_302621_2 1210884.HG799462_gene8087 0.000134 47.0 COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth SRR21617311_k127_303930_1 1449126.JQKL01000036_gene1950 9.322e-51 200.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_303930_0 234267.Acid_4124 4.441e-110 386.0 COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS SRR21617311_k127_303930_2 313596.RB2501_12904 4.352e-33 149.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - ko:K08738,ko:K20276 ko00920,ko01100,ko01120,ko01524,ko02020,ko02024,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map02024,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Beta_helix,CBM_6,CHU_C,CW_binding_2,DUF11,GSDH,MAM,Malectin,PKD,fn3 SRR21617311_k127_30895_0 945713.IALB_0909 1.329e-103 341.0 COG0480@1|root,COG0480@2|Bacteria 2|Bacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR21617311_k127_30895_1 335543.Sfum_1552 6.467e-58 205.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MRJC@213462|Syntrophobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 SRR21617311_k127_30895_2 1379698.RBG1_1C00001G1603 6.674e-53 187.0 COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria 2|Bacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 SRR21617311_k127_310478_0 1379698.RBG1_1C00001G1364 2.934e-131 432.0 COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005,ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP SRR21617311_k127_310478_1 1379698.RBG1_1C00001G1363 6.656e-76 271.0 COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria 2|Bacteria MU Outer membrane efflux protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP SRR21617311_k127_312862_0 1379698.RBG1_1C00001G0703 1.179e-132 435.0 COG0124@1|root,COG0124@2|Bacteria,2NNZ7@2323|unclassified Bacteria 2|Bacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His SRR21617311_k127_312862_2 204669.Acid345_1829 3.183e-24 115.0 COG0457@1|root,COG0457@2|Bacteria,3Y4RD@57723|Acidobacteria,2JJAQ@204432|Acidobacteriia 204432|Acidobacteriia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8 SRR21617311_k127_312862_3 880073.Calab_2081 4.011e-16 92.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD SRR21617311_k127_312862_1 1379698.RBG1_1C00001G0429 1.499e-75 259.0 COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria 2|Bacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 SRR21617311_k127_313373_2 459349.CLOAM0985 8.812e-10 59.0 COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 SRR21617311_k127_313373_0 671143.DAMO_1170 4.367e-61 214.0 COG1970@1|root,COG1970@2|Bacteria,2NPH6@2323|unclassified Bacteria 2|Bacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL SRR21617311_k127_313373_1 1379698.RBG1_1C00001G1798 1.127e-49 181.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization - - - - - - - - - - - - - SRR21617311_k127_314343_1 1379698.RBG1_1C00001G0394 6.683e-109 364.0 COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M SRR21617311_k127_314343_0 1379698.RBG1_1C00001G0393 4.256e-170 540.0 COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria 2|Bacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Glycos_transf_4,MraY_sig1 SRR21617311_k127_314343_2 1379698.RBG1_1C00001G0392 5.875e-21 96.0 COG0770@1|root,COG0770@2|Bacteria,2NP4Q@2323|unclassified Bacteria 2|Bacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR21617311_k127_320140_0 1379698.RBG1_1C00001G1850 8.584e-95 319.0 COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria 2|Bacteria S Rhomboid family - - - - - - - - - - - - Rhomboid SRR21617311_k127_320140_1 1232410.KI421424_gene1655 6.093e-11 75.0 COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,43S2C@69541|Desulfuromonadales 28221|Deltaproteobacteria T histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg SRR21617311_k127_32412_1 888060.HMPREF9081_1514 3.207e-36 141.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4H4MK@909932|Negativicutes 909932|Negativicutes S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY SRR21617311_k127_32412_2 1379698.RBG1_1C00001G1483 7.355e-34 139.0 COG1286@1|root,COG1286@2|Bacteria,2NQ58@2323|unclassified Bacteria 2|Bacteria S Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V SRR21617311_k127_32412_3 258594.RPA2307 1.76e-26 122.0 COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2TXET@28211|Alphaproteobacteria,3K6U1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P TonB dependent receptor - - - ko:K16087,ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10,1.B.14.2 - - Plug,TonB_dep_Rec SRR21617311_k127_324581_0 1379698.RBG1_1C00001G1526 1.926e-67 241.0 2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria 2|Bacteria S Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - YjbH SRR21617311_k127_331582_6 935261.JAGL01000019_gene570 4.446e-19 93.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,43I6J@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI SRR21617311_k127_331582_3 1121430.JMLG01000021_gene1380 9.133e-32 131.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,261RC@186807|Peptococcaceae 186801|Clostridia F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CM_2,SKI SRR21617311_k127_331582_5 525903.Taci_0185 6.484e-29 121.0 COG0370@1|root,COG0370@2|Bacteria,3TC88@508458|Synergistetes 508458|Synergistetes P PFAM Nucleoside recognition - - - - - - - - - - - - Gate SRR21617311_k127_331582_4 1379698.RBG1_1C00001G1533 3.832e-31 128.0 COG0370@1|root,COG0370@2|Bacteria 2|Bacteria P ferrous iron transmembrane transporter activity yvoD - - - - - - - - - - - Gate SRR21617311_k127_331582_2 264732.Moth_1558 1.498e-61 224.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,42ES9@68295|Thermoanaerobacterales 186801|Clostridia E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N SRR21617311_k127_331582_0 315730.BcerKBAB4_2747 4.417e-118 401.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase SRR21617311_k127_331582_1 1382359.JIAL01000001_gene383 4.36e-76 257.0 COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia 204432|Acidobacteriia E NeuB family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 SRR21617311_k127_333173_1 1379698.RBG1_1C00001G1824 5.269e-32 126.0 COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt SRR21617311_k127_333173_0 1379698.RBG1_1C00001G1823 1.535e-69 246.0 COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria 2|Bacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm SRR21617311_k127_340140_0 1379698.RBG1_1C00001G0696 1.607e-226 707.0 COG1301@1|root,COG1301@2|Bacteria,2NP6X@2323|unclassified Bacteria 2|Bacteria U Sodium:dicarboxylate symporter family gltP - - ko:K03309 - - - - ko00000 2.A.23 - - SDF SRR21617311_k127_340140_2 42256.RradSPS_2906 1.169e-124 418.0 COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria 201174|Actinobacteria S Uncharacterised conserved protein (DUF2156) lysX - 2.3.2.3,6.1.1.6 ko:K04567,ko:K14205 ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150 M00359,M00360,M00726 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016 2.A.1.3.37 - - DUF2156,tRNA-synt_2_TM SRR21617311_k127_340140_7 717785.HYPMC_0776 0.000402 53.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,3N72Y@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 SRR21617311_k127_340140_4 234267.Acid_5547 2.711e-60 222.0 COG0392@1|root,COG0392@2|Bacteria,3Y7S6@57723|Acidobacteria 57723|Acidobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM SRR21617311_k127_340140_3 1379698.RBG1_1C00001G0252 2.375e-75 258.0 COG2323@1|root,COG2323@2|Bacteria,2NR09@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 SRR21617311_k127_340140_1 1254432.SCE1572_04890 1.679e-167 537.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 SRR21617311_k127_340140_6 1379698.RBG1_1C00001G0407 7.598e-52 184.0 COG0823@1|root,COG0823@2|Bacteria,2NQA4@2323|unclassified Bacteria 2|Bacteria U Periplasmic component of the Tol biopolymer transport system tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PA,PD40,PDZ_2,Peptidase_M28 SRR21617311_k127_360765_0 56780.SYN_01854 5.209e-91 324.0 COG1204@1|root,COG1204@2|Bacteria,1MW4Z@1224|Proteobacteria,42TK8@68525|delta/epsilon subdivisions,2WQUX@28221|Deltaproteobacteria 28221|Deltaproteobacteria L helicase superfamily c-terminal domain - - - ko:K03726 - - - - ko00000,ko01000 - - - DEAD,Helicase_C SRR21617311_k127_365901_0 1379698.RBG1_1C00001G0095 3.1e-36 140.0 COG0316@1|root,COG0316@2|Bacteria,2NPZK@2323|unclassified Bacteria 2|Bacteria S Belongs to the HesB IscA family ycf57 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SRR21617311_k127_365901_1 1379698.RBG1_1C00001G0093 1.46e-30 128.0 COG0633@1|root,COG0633@2|Bacteria 2|Bacteria C Ferredoxin fdx GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - ko:K04755 - - - - ko00000 - - - Fer2 SRR21617311_k127_379723_0 1379698.RBG1_1C00001G0078 1.138e-154 491.0 COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria 2|Bacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547,iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536 ACR_tran SRR21617311_k127_379723_1 1379698.RBG1_1C00001G0079 2.704e-106 359.0 COG0845@1|root,COG0845@2|Bacteria,2NP3Y@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23,HlyD_D4 SRR21617311_k127_379723_2 404380.Gbem_2166 6.484e-65 239.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity cebC - - - - - - - - - - - OEP SRR21617311_k127_386913_0 1379698.RBG1_1C00001G0584 1.156e-74 270.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL SRR21617311_k127_387978_2 880073.Calab_2485 5.342e-19 88.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - FlgD_ig,Fn3-like,Glyco_hydro_3_C,SLH SRR21617311_k127_387978_0 1379698.RBG1_1C00001G1004 5.951e-135 441.0 COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria 2|Bacteria D Peptidoglycan polymerase that is essential for cell wall elongation rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE SRR21617311_k127_387978_1 1379698.RBG1_1C00001G1003 3.483e-121 400.0 COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding protein 2 mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase SRR21617311_k127_388398_0 509635.N824_22580 3.473e-88 306.0 COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1IQZS@117747|Sphingobacteriia 976|Bacteroidetes E PFAM peptidase T2 asparaginase 2 aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 ko:K01444,ko:K13051 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 SRR21617311_k127_388398_2 1379698.RBG1_1C00001G0668 1.888e-24 120.0 COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria 2|Bacteria M Hep Hag repeat protein - - 3.4.24.40 ko:K01406,ko:K21449 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - DUF1566,Phenol_MetA_deg SRR21617311_k127_388398_4 1457250.BBMO01000002_gene2310 1.005e-23 118.0 COG0419@1|root,arCOG00368@2157|Archaea 2157|Archaea L Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - - - - - - - - - - MMPL,PQQ_2,Peptidase_S74,Pkinase SRR21617311_k127_388398_3 1121957.ATVL01000008_gene4553 6.579e-24 105.0 COG5295@1|root,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia 976|Bacteroidetes MUW domain, Protein - - - - - - - - - - - - Peptidase_S74 SRR21617311_k127_388398_1 471854.Dfer_2527 1.954e-46 186.0 COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia 976|Bacteroidetes Q SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - CHU_C,FG-GAP,HYR,VCBS SRR21617311_k127_393182_1 945713.IALB_2070 3.266e-29 131.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - TraF_2 SRR21617311_k127_393182_0 290402.Cbei_4620 1.596e-45 173.0 COG2148@1|root,COG2148@2|Bacteria,1TP7V@1239|Firmicutes,25AZD@186801|Clostridia,36FX6@31979|Clostridiaceae 186801|Clostridia M Bacterial sugar transferase pglB - - - - - - - - - - - Bac_transf SRR21617311_k127_397320_1 1379698.RBG1_1C00001G1773 1.771e-67 239.0 COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria 2|Bacteria S Oxygen tolerance - - - - - - - - - - - - BatD SRR21617311_k127_397320_3 435591.BDI_0950 3.255e-15 86.0 COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,2FN6E@200643|Bacteroidia,22XZA@171551|Porphyromonadaceae 976|Bacteroidetes S Tetratricopeptide repeat batC - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 SRR21617311_k127_397320_0 1379698.RBG1_1C00001G1774 4.054e-109 365.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria 2|Bacteria S von Willebrand factor (vWF) type A domain batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 SRR21617311_k127_397320_2 1379698.RBG1_1C00001G1775 9.603e-19 87.0 COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria 2|Bacteria NU von Willebrand factor (vWF) type A domain batA - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA SRR21617311_k127_401206_1 1379698.RBG1_1C00001G1628 3.258e-66 230.0 COG0634@1|root,COG0634@2|Bacteria,2NPER@2323|unclassified Bacteria 2|Bacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 ko:K00760,ko:K00939,ko:K15780 ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130 M00049 R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319 RC00002,RC00063,RC00122 ko00000,ko00001,ko00002,ko01000,ko03016,ko04147 - - iHN637.CLJU_RS16720 ADK,Pribosyltran SRR21617311_k127_401206_0 1379698.RBG1_1C00001G1629 3.86e-104 357.0 COG0037@1|root,COG0037@2|Bacteria,2NPAZ@2323|unclassified Bacteria 2|Bacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS_C SRR21617311_k127_401206_2 671143.DAMO_0227 8.775e-05 46.0 COG2852@1|root,COG2852@2|Bacteria,2NQ8X@2323|unclassified Bacteria 2|Bacteria V Protein of unknown function (DUF559) - - - - - - - - - - - - DUF559 SRR21617311_k127_401595_2 1519464.HY22_02585 2.405e-85 293.0 COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi 1090|Chlorobi M Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SRR21617311_k127_401595_0 1379698.RBG1_1C00001G1854 1.623e-183 580.0 COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria 2|Bacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N SRR21617311_k127_401595_1 868864.Dester_1104 5.425e-177 563.0 COG0499@1|root,COG0499@2|Bacteria,2G3TI@200783|Aquificae 200783|Aquificae H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD SRR21617311_k127_408002_0 1379698.RBG1_1C00001G0877 2.571e-82 284.0 COG2027@1|root,COG2027@2|Bacteria,2NP5E@2323|unclassified Bacteria 2|Bacteria M COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 SRR21617311_k127_408002_1 1379698.RBG1_1C00001G0878 1.336e-48 185.0 COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria 2|Bacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N SRR21617311_k127_415820_4 742767.HMPREF9456_01678 7.811e-42 160.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FME3@200643|Bacteroidia,22X07@171551|Porphyromonadaceae 976|Bacteroidetes M Peptidase, M23 - - - - - - - - - - - - Peptidase_M23 SRR21617311_k127_415820_2 1379698.RBG1_1C00001G1702 2.663e-60 218.0 COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 SRR21617311_k127_415820_3 1379698.RBG1_1C00001G1700 1.413e-54 206.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity MA20_20705 - 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR21617311_k127_415820_1 401526.TcarDRAFT_2677 5.215e-203 654.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4H28C@909932|Negativicutes 909932|Negativicutes L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C SRR21617311_k127_415820_0 1379698.RBG1_1C00001G1698 3.715e-204 644.0 COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria 2|Bacteria E Pyridoxal-phosphate dependent enzyme cysK - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP SRR21617311_k127_415820_5 1379698.RBG1_1C00001G0683 1.708e-29 121.0 COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria 2|Bacteria P (Rieske (2Fe-2S) domain) - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske SRR21617311_k127_415820_6 1379698.RBG1_1C00001G0730 2.571e-28 117.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS SRR21617311_k127_419047_3 1379698.RBG1_1C00001G1502 1.51e-07 52.0 COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria 2|Bacteria NU Type II/IV secretion system protein pilT-1 - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SRR21617311_k127_419047_0 1379698.RBG1_1C00001G1501 4.425e-201 636.0 COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria 2|Bacteria I acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 SRR21617311_k127_419047_2 1379698.RBG1_1C00001G1500 1.247e-52 189.0 COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H SRR21617311_k127_419047_1 1379698.RBG1_1C00001G1499 4.102e-173 555.0 COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P SRR21617311_k127_421066_0 1379698.RBG1_1C00001G1136 5.738e-100 338.0 COG2956@1|root,COG2956@2|Bacteria 2|Bacteria G lipopolysaccharide metabolic process ciaB - - ko:K07502,ko:K08309,ko:K19804,ko:K21572 - - - - ko00000,ko01000,ko01011,ko02000 8.A.46.1,8.A.46.3 GH23 - SusD-like_3,SusD_RagB,TPR_16,TPR_6,TPR_8 SRR21617311_k127_42108_3 1211817.CCAT010000007_gene1134 8.437e-71 250.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,36DEJ@31979|Clostridiaceae 186801|Clostridia J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS SRR21617311_k127_42108_1 1379698.RBG1_1C00001G1019 1.089e-98 330.0 COG0528@1|root,COG0528@2|Bacteria,2NNRY@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase SRR21617311_k127_42108_2 1379698.RBG1_1C00001G1020 1.82e-71 249.0 COG0233@1|root,COG0233@2|Bacteria,2NPEP@2323|unclassified Bacteria 2|Bacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF SRR21617311_k127_42108_9 1173022.Cri9333_2967 2.211e-17 86.0 COG1943@1|root,COG1943@2|Bacteria,1G5Y7@1117|Cyanobacteria,1HCR7@1150|Oscillatoriales 1117|Cyanobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp SRR21617311_k127_42108_0 1379698.RBG1_1C00001G1021 4.036e-102 338.0 COG0020@1|root,COG0020@2|Bacteria,2NP9M@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 ko:K00806,ko:K12503 ko00900,ko01110,map00900,map01110 - R06447,R08528 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf SRR21617311_k127_42108_5 1379698.RBG1_1C00001G1022 3.408e-64 235.0 COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria 2|Bacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 SRR21617311_k127_42108_6 1379698.RBG1_1C00001G1024 8.655e-56 206.0 COG0382@1|root,COG0382@2|Bacteria,2NRJ9@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family - - 2.5.1.133,2.5.1.39,2.5.1.62 ko:K03179,ko:K04040 ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110 M00117 R05000,R05615,R06284,R09067,R11514,R11517 RC00020,RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA SRR21617311_k127_42108_7 324057.Pjdr2_0116 1.838e-24 109.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HH84@91061|Bacilli,26SGY@186822|Paenibacillaceae 91061|Bacilli M Hydrolase spr1 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,SH3_3 SRR21617311_k127_42108_8 1033743.CAES01000019_gene3249 4.037e-21 96.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,26RB9@186822|Paenibacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N SRR21617311_k127_42108_4 1379698.RBG1_1C00001G1025 1.852e-70 242.0 COG0322@1|root,COG0322@2|Bacteria,2NNQ4@2323|unclassified Bacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N SRR21617311_k127_42754_0 1379698.RBG1_1C00001G1601 2.033e-232 726.0 COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria 2|Bacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR21617311_k127_42754_3 1379698.RBG1_1C00001G1598 2.819e-42 159.0 COG0051@1|root,COG0051@2|Bacteria,2NPJY@2323|unclassified Bacteria 2|Bacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 SRR21617311_k127_42754_1 1379698.RBG1_1C00001G1596 7.476e-73 258.0 COG0087@1|root,COG0087@2|Bacteria,2NPAI@2323|unclassified Bacteria 2|Bacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 SRR21617311_k127_42754_2 1379698.RBG1_1C00001G1595 5.857e-55 205.0 COG0088@1|root,COG0088@2|Bacteria,2NPF3@2323|unclassified Bacteria 2|Bacteria J Forms part of the polypeptide exit tunnel rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926,ko:K16193 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 SRR21617311_k127_427872_1 1140.Synpcc7942_1337 1.986e-52 201.0 COG2273@1|root,COG2931@1|root,COG2273@2|Bacteria,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus 1117|Cyanobacteria Q Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Calx-beta,FG-GAP SRR21617311_k127_427872_0 1379698.RBG1_1C00001G0322 4.34e-77 275.0 COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria 2|Bacteria D Stage II sporulation protein - - - ko:K06381 - - - - ko00000 - - - SpoIID SRR21617311_k127_427872_2 1297617.JPJD01000007_gene73 1.013e-30 125.0 COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,26AKN@186813|unclassified Clostridiales 186801|Clostridia F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK SRR21617311_k127_429880_3 1379698.RBG1_1C00001G0419 2.556e-51 185.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 ko:K00260,ko:K00261,ko:K00262 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.gdhA ELFV_dehydrog,ELFV_dehydrog_N SRR21617311_k127_429880_1 1379698.RBG1_1C00001G0400 3.971e-137 446.0 COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria 2|Bacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin SRR21617311_k127_429880_2 1379698.RBG1_1C00001G0399 2.268e-104 354.0 COG0849@1|root,COG0849@2|Bacteria,2NNU2@2323|unclassified Bacteria 2|Bacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SRR21617311_k127_429880_5 1379698.RBG1_1C00001G0398 1.474e-25 115.0 COG1589@1|root,COG1589@2|Bacteria,2NQ2T@2323|unclassified Bacteria 2|Bacteria D Essential cell division protein ftsQ - - ko:K03589,ko:K06438 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1,YqfD SRR21617311_k127_429880_0 1379698.RBG1_1C00001G0397 2.631e-182 582.0 COG0773@1|root,COG0773@2|Bacteria,2NNPU@2323|unclassified Bacteria 2|Bacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093,iJN678.murC Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR21617311_k127_429880_4 1379698.RBG1_1C00001G0396 1.96e-46 175.0 COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 SRR21617311_k127_43092_2 926569.ANT_28870 2.226e-75 267.0 COG0863@1|root,COG0863@2|Bacteria,2G7IH@200795|Chloroflexi 200795|Chloroflexi L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SRR21617311_k127_43092_1 1379698.RBG1_1C00001G0710 6.115e-91 302.0 COG1945@1|root,COG1945@2|Bacteria,2NP74@2323|unclassified Bacteria 2|Bacteria S Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) pdaD - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC SRR21617311_k127_43092_0 1379698.RBG1_1C00001G0711 2.766e-176 565.0 COG0612@1|root,COG0612@2|Bacteria,2NQHV@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) ymxG - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_43092_3 1379698.RBG1_1C00001G0712 6.947e-31 125.0 COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_434458_1 1449126.JQKL01000036_gene1950 2.448e-62 237.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_434458_0 1379270.AUXF01000004_gene3268 3.077e-128 429.0 COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes 142182|Gemmatimonadetes P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate SRR21617311_k127_44386_1 1379698.RBG1_1C00001G1858 7.02e-128 421.0 COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria 2|Bacteria S Permease YjgP YjgQ family protein lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K07091,ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 YjgP_YjgQ SRR21617311_k127_44386_3 1379698.RBG1_1C00001G1859 2.835e-105 350.0 COG3481@1|root,COG3481@2|Bacteria,2NPNP@2323|unclassified Bacteria 2|Bacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM - - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon SRR21617311_k127_44386_0 1379698.RBG1_1C00001G1860 1.211e-186 587.0 COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria 2|Bacteria D MreB/Mbl protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SRR21617311_k127_44386_2 1379698.RBG1_1C00001G1253 3.048e-116 389.0 COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria 2|Bacteria I COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR21617311_k127_444173_5 1265505.ATUG01000002_gene1765 8.899e-47 171.0 COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria,2MN6R@213118|Desulfobacterales 28221|Deltaproteobacteria E GXGXG motif - - - - - - - - - - - - GATase_6,GXGXG SRR21617311_k127_444173_2 1283299.AUKG01000001_gene3451 3.221e-61 230.0 COG1361@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - DUF11,FG-GAP,HemolysinCabind SRR21617311_k127_444173_6 1379698.RBG1_1C00001G0697 1.972e-36 141.0 29XH8@1|root,30J7X@2|Bacteria,2NS24@2323|unclassified Bacteria 2|Bacteria J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP SRR21617311_k127_444173_7 1121355.KB903379_gene745 0.0001071 44.0 COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae 201174|Actinobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SRR21617311_k127_444173_3 1121468.AUBR01000001_gene469 2.404e-59 213.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42GAD@68295|Thermoanaerobacterales 186801|Clostridia F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like SRR21617311_k127_444173_1 1379698.RBG1_1C00001G0722 1.948e-91 308.0 COG0796@1|root,COG0796@2|Bacteria,2NP3D@2323|unclassified Bacteria 2|Bacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race SRR21617311_k127_444173_0 1379698.RBG1_1C00001G0723 1.05e-111 379.0 COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria 2|Bacteria M Ami_3 amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 SRR21617311_k127_444173_4 1033734.CAET01000035_gene3219 1.833e-50 184.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus 91061|Bacilli O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB SRR21617311_k127_453267_1 243231.GSU0434 9.438e-90 308.0 COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,43T42@69541|Desulfuromonadales 28221|Deltaproteobacteria H Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - DUF814,ThiI SRR21617311_k127_453267_2 247490.KSU1_B0729 8.209e-64 226.0 COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes 203682|Planctomycetes P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU SRR21617311_k127_453267_0 330214.NIDE2417 1.53e-101 337.0 COG1117@1|root,COG1117@2|Bacteria,3J0EU@40117|Nitrospirae 40117|Nitrospirae P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran SRR21617311_k127_453952_0 1382306.JNIM01000001_gene2893 2.316e-90 310.0 COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi 200795|Chloroflexi M PFAM Mandelate racemase muconate lactonizing protein - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N SRR21617311_k127_453952_1 1379698.RBG1_1C00001G0879 1.268e-87 300.0 COG1619@1|root,COG1619@2|Bacteria,2NPYN@2323|unclassified Bacteria 2|Bacteria V LD-carboxypeptidase ldcA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 SRR21617311_k127_453952_2 697281.Mahau_2177 1.44e-40 153.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,42EZ0@68295|Thermoanaerobacterales 186801|Clostridia M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N SRR21617311_k127_454158_1 1379698.RBG1_1C00001G0172 2.999e-48 177.0 COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria 2|Bacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SRR21617311_k127_454158_0 1379698.RBG1_1C00001G0168 1.441e-108 356.0 COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria 2|Bacteria M Nucleotidyl transferase spsI - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SRR21617311_k127_454158_3 1206725.BAFU01000064_gene317 0.0001413 51.0 COG3832@1|root,COG3832@2|Bacteria,2I4FM@201174|Actinobacteria 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SRR21617311_k127_454158_2 1379698.RBG1_1C00001G0167 1.764e-20 94.0 COG1898@1|root,COG1898@2|Bacteria,2NP7U@2323|unclassified Bacteria 2|Bacteria M dTDP-4-dehydrorhamnose 3,5-epimerase - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom SRR21617311_k127_460484_6 1379698.RBG1_1C00001G1337 2.358e-08 58.0 COG2372@1|root,COG2372@2|Bacteria,2NQ3Q@2323|unclassified Bacteria 2|Bacteria S Bacterial Ig-like domain - - - ko:K07156 - - - - ko00000,ko02000 9.B.62.2 - - Big_5,DUF4082,SLH SRR21617311_k127_460484_2 1379698.RBG1_1C00001G1338 1.191e-69 256.0 COG0457@1|root,COG0457@2|Bacteria,2NPEN@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_8 SRR21617311_k127_460484_5 1499967.BAYZ01000190_gene3859 6.164e-11 74.0 COG3227@1|root,COG4447@1|root,COG3227@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 2.7.11.1,3.4.24.25 ko:K08604,ko:K12132 ko05110,ko05111,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko01002 - - - ChW,Cu_amine_oxidN1,F5_F8_type_C,Peptidase_M4,Peptidase_M4_C SRR21617311_k127_460484_3 1379698.RBG1_1C00001G0593 5.648e-35 145.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,Cadherin_3,DUF11,FlgD_ig SRR21617311_k127_460484_4 269797.Mbar_A2963 6.556e-35 135.0 COG2151@1|root,arCOG01845@2157|Archaea,2Y0P6@28890|Euryarchaeota 28890|Euryarchaeota S metal-sulfur cluster biosynthetic enzyme - - - - - - - - - - - - FeS_assembly_P SRR21617311_k127_460484_1 1379698.RBG1_1C00001G1874 2.02e-88 302.0 COG0351@1|root,COG0351@2|Bacteria,2NP3M@2323|unclassified Bacteria 2|Bacteria H Phosphomethylpyrimidine kinase thiD - 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2909 Phos_pyr_kin,TMP-TENI SRR21617311_k127_460484_0 1379698.RBG1_1C00001G1873 1.084e-106 350.0 COG0379@1|root,COG0379@2|Bacteria,2NP47@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SRR21617311_k127_462906_1 502025.Hoch_6792 6.927e-42 160.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF4388,PEGA,Pkinase SRR21617311_k127_462906_0 1047013.AQSP01000108_gene2058 2.89e-123 405.0 COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 SRR21617311_k127_46912_0 1379698.RBG1_1C00001G1107 8.671e-69 244.0 COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria 2|Bacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_4 SRR21617311_k127_46912_1 386456.JQKN01000015_gene2945 7.569e-51 186.0 COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria 183925|Methanobacteria S PFAM LemA - - - - - - - - - - - - LemA SRR21617311_k127_46912_2 378806.STAUR_1951 3.134e-08 60.0 COG0457@1|root,COG0457@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YZCB@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_14,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8 SRR21617311_k127_470448_2 1379698.RBG1_1C00001G0202 1.242e-46 169.0 COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SRR21617311_k127_470448_4 1170562.Cal6303_2768 9.444e-33 131.0 COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales 1117|Cyanobacteria J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP SRR21617311_k127_470448_5 1229909.NSED_09230 0.0007678 48.0 COG5615@1|root,arCOG05392@2157|Archaea,41T4B@651137|Thaumarchaeota 651137|Thaumarchaeota S Copper resistance protein D - - - - - - - - - - - - CopD SRR21617311_k127_470448_1 399549.Msed_2173 9.238e-52 196.0 COG0489@1|root,arCOG00585@2157|Archaea,2XPV2@28889|Crenarchaeota 28889|Crenarchaeota D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - ParA SRR21617311_k127_470448_3 266117.Rxyl_0137 4.681e-44 175.0 COG0449@1|root,COG0449@2|Bacteria,2IIQ7@201174|Actinobacteria,4CQF9@84995|Rubrobacteria 84995|Rubrobacteria M glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - - SRR21617311_k127_470448_0 1379698.RBG1_1C00001G0291 1.98e-92 311.0 COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria 2|Bacteria E Peptidase family M20/M25/M40 - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42 SRR21617311_k127_473025_2 1379698.RBG1_1C00001G0456 9.132e-118 400.0 COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria 2|Bacteria O Peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3 SRR21617311_k127_473025_5 1094980.Mpsy_3016 4.431e-20 94.0 COG4892@1|root,arCOG02922@2157|Archaea 2157|Archaea S Cytochrome b5-like Heme/Steroid binding domain - - - - - - - - - - - - Cyt-b5 SRR21617311_k127_473025_3 1379698.RBG1_1C00001G0521 5.33e-116 384.0 COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria 2|Bacteria C Dehydrogenase E1 component bfmBA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C SRR21617311_k127_473025_0 1379698.RBG1_1C00001G0522 2.716e-154 492.0 COG0022@1|root,COG0022@2|Bacteria,2NNT2@2323|unclassified Bacteria 2|Bacteria C Transketolase, pyrimidine binding domain pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 ko:K00162,ko:K00167,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2496c,iSB619.SA_RS05355,iYO844.BSU14590,iYO844.BSU24040 Transket_pyr,Transketolase_C SRR21617311_k127_473025_1 1379698.RBG1_1C00001G0523 1.159e-139 455.0 COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria 2|Bacteria C e3 binding domain sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding SRR21617311_k127_473025_4 765912.Thimo_3174 2.827e-111 370.0 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr SRR21617311_k127_473400_0 1379698.RBG1_1C00001G0970 1.37e-71 256.0 COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PMT_2 SRR21617311_k127_473400_1 1379698.RBG1_1C00001G0829 1.456e-59 226.0 COG4775@1|root,COG4775@2|Bacteria,2NRXR@2323|unclassified Bacteria 2|Bacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SRR21617311_k127_475053_4 1173028.ANKO01000159_gene5219 4.171e-13 72.0 COG0642@1|root,COG2205@2|Bacteria,1G3AM@1117|Cyanobacteria,1HA0Y@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,cNMP_binding SRR21617311_k127_475053_3 1123368.AUIS01000001_gene1898 2.916e-16 91.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2NE6V@225057|Acidithiobacillales 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 SRR21617311_k127_475053_0 1379698.RBG1_1C00001G0675 9.849e-121 399.0 COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria 2|Bacteria E Saccharopine dehydrogenase C-terminal domain lysDH - 1.4.1.18 ko:K19064 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R00446,R02317 RC00062,RC00694 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP SRR21617311_k127_475053_1 402777.KB235904_gene3532 3.533e-91 306.0 COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales 1117|Cyanobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 SRR21617311_k127_475053_2 1429916.X566_09325 8.425e-44 165.0 2BZ9H@1|root,33PVS@2|Bacteria,1NRJ5@1224|Proteobacteria,2UQ2G@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_480732_1 1535422.ND16A_1227 1.584e-07 60.0 COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1T8KC@1236|Gammaproteobacteria,2Q8A4@267889|Colwelliaceae 1236|Gammaproteobacteria S cellulase activity - - - - - - - - - - - - - SRR21617311_k127_480732_0 1229172.JQFA01000002_gene2792 1.397e-19 102.0 COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales 1117|Cyanobacteria M Phosphotransferase enzyme family - - - - - - - - - - - - APH SRR21617311_k127_482184_1 485913.Krac_9046 1.792e-34 134.0 COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB SRR21617311_k127_482184_0 1379698.RBG1_1C00001G1054 2.004e-49 182.0 COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria 2|Bacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx SRR21617311_k127_482322_3 1379698.RBG1_1C00001G0560 7.681e-87 294.0 COG0483@1|root,COG0483@2|Bacteria,2NP94@2323|unclassified Bacteria 2|Bacteria G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 - - - Inositol_P SRR21617311_k127_482322_8 1379698.RBG1_1C00001G0559 1.211e-42 161.0 COG1656@1|root,COG1656@2|Bacteria,2NPUJ@2323|unclassified Bacteria 2|Bacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C SRR21617311_k127_482322_6 1379698.RBG1_1C00001G0561 1.513e-45 174.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02490 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c,HisKA_2,PAS_3,PAS_9,Response_reg,SpoIIE SRR21617311_k127_482322_1 1379698.RBG1_1C00001G0568 7.085e-192 608.0 COG1109@1|root,COG1109@2|Bacteria,2NNRE@2323|unclassified Bacteria 2|Bacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III manB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SRR21617311_k127_482322_2 1379698.RBG1_1C00001G1801 1.027e-130 420.0 COG1028@1|root,COG1028@2|Bacteria,2NPES@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 SRR21617311_k127_482322_5 247490.KSU1_D0846 1.064e-58 207.0 2B5RU@1|root,31YMF@2|Bacteria,2J42A@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SRR21617311_k127_482322_4 909663.KI867150_gene69 6.038e-78 267.0 arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SRR21617311_k127_482322_0 56780.SYN_01455 1.007e-221 696.0 COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,42QJ3@68525|delta/epsilon subdivisions,2WKUT@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Beta-eliminating lyase - - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase SRR21617311_k127_482322_7 1121878.AUGL01000006_gene674 1.052e-44 163.0 COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Seven times multi-haem cytochrome CxxCH - - 1.7.2.6 ko:K10535 ko00910,ko01120,map00910,map01120 M00528,M00804 R10164 RC00383 ko00000,ko00001,ko00002,ko01000 - - - Multi-haem_cyto SRR21617311_k127_48392_2 1283299.AUKG01000005_gene1 3.566e-10 73.0 COG3055@1|root,COG3055@2|Bacteria,2HRRN@201174|Actinobacteria,4CTUC@84995|Rubrobacteria 84995|Rubrobacteria U Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - - SRR21617311_k127_48392_1 1379698.RBG1_1C00001G0592 1.407e-20 106.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - HemolysinCabind SRR21617311_k127_48392_0 365044.Pnap_2178 1.618e-42 170.0 2A2RR@1|root,30R50@2|Bacteria,1RF6F@1224|Proteobacteria,2VYJ0@28216|Betaproteobacteria 28216|Betaproteobacteria S Alginate export - - - ko:K16081 - - - - ko00000,ko02000 1.B.13.1 - - Alginate_exp SRR21617311_k127_492435_0 1379698.RBG1_1C00001G1820 8.847e-313 992.0 COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec SRR21617311_k127_492435_1 1399115.U719_04675 1.311e-08 61.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3WEEU@539002|Bacillales incertae sedis 91061|Bacilli H Lipoate--protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SRR21617311_k127_516669_0 1121405.dsmv_2388 1.255e-73 252.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales 28221|Deltaproteobacteria I PFAM Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SRR21617311_k127_516669_1 671065.MetMK1DRAFT_00016440 7.527e-35 137.0 COG3396@1|root,arCOG04786@2157|Archaea 2157|Archaea S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC SRR21617311_k127_528304_0 1379698.RBG1_1C00001G1138 6.207e-298 938.0 COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria 2|Bacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V SRR21617311_k127_528304_1 945713.IALB_1261 1.751e-24 109.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 SRR21617311_k127_531420_2 266117.Rxyl_0166 1.654e-29 119.0 COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria 84995|Rubrobacteria E Aminotransferase class-V - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 SRR21617311_k127_531420_0 1379698.RBG1_1C00001G0740 1.113e-60 214.0 COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria 2|Bacteria C NifU-like N terminal domain iscU - - ko:K04488 - - - - ko00000 - - - NifU_N SRR21617311_k127_531420_3 1379698.RBG1_1C00001G0741 2.92e-27 115.0 COG2151@1|root,COG2151@2|Bacteria 2|Bacteria L metal-sulfur cluster biosynthetic enzyme yitW - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P SRR21617311_k127_531420_1 880073.Calab_0035 1.474e-35 153.0 COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Big_2,FlgD_ig,SLH SRR21617311_k127_533548_0 1379698.RBG1_1C00001G0222 5.227e-114 378.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria 2|Bacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N SRR21617311_k127_533548_2 1379698.RBG1_1C00001G0223 2.308e-86 296.0 COG0284@1|root,COG0284@2|Bacteria,2NP92@2323|unclassified Bacteria 2|Bacteria F Belongs to the OMP decarboxylase family. Type 2 subfamily pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS17585 OMPdecase SRR21617311_k127_533548_1 1121403.AUCV01000004_gene2028 5.624e-97 326.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MIHH@213118|Desulfobacterales 28221|Deltaproteobacteria F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SRR21617311_k127_533548_5 694431.DESACE_04480 4.779e-12 71.0 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,2M6WQ@213113|Desulfurellales 28221|Deltaproteobacteria CH Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 SRR21617311_k127_533548_4 1121468.AUBR01000005_gene6 3.092e-33 139.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GEQ@68295|Thermoanaerobacterales 186801|Clostridia C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 SRR21617311_k127_533548_3 1379698.RBG1_1C00001G0226 6.513e-85 299.0 COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 SRR21617311_k127_540780_2 1379698.RBG1_1C00001G1420 2.28e-59 230.0 COG0457@1|root,COG0457@2|Bacteria 1379698.RBG1_1C00001G1420|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SRR21617311_k127_540780_1 1379698.RBG1_1C00001G1421 6.669e-173 567.0 COG4191@1|root,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria 2|Bacteria T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS_4,PAS_8,PAS_9,Response_reg SRR21617311_k127_540780_3 1379698.RBG1_1C00001G1423 1.092e-39 166.0 COG2203@1|root,COG2203@2|Bacteria 2|Bacteria T Gaf domain - - - - - - - - - - - - GAF,GAF_2,GGDEF,HD,HD_5 SRR21617311_k127_546576_0 1379698.RBG1_1C00001G1787 4.381e-191 630.0 COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - DUF1863,PQQ_2 SRR21617311_k127_546576_3 1379698.RBG1_1C00001G1786 1.307e-42 169.0 2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_546576_2 1379698.RBG1_1C00001G1785 1.157e-44 172.0 2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_546576_4 1379698.RBG1_1C00001G1784 1.648e-31 136.0 COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria 2|Bacteria O NHL repeat - - - - - - - - - - - - Cu_amine_oxidN1,DUF5128,NHL SRR21617311_k127_546576_1 1379698.RBG1_1C00001G1783 5.047e-51 208.0 COG5448@1|root,COG5448@2|Bacteria,2NPPC@2323|unclassified Bacteria 2|Bacteria S Glycoside hydrolase family 24 - - - - - - - - - - - - DUF2460 SRR21617311_k127_550383_2 1379698.RBG1_1C00001G1640 4.352e-10 61.0 COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_550383_1 1379698.RBG1_1C00001G1640 5.43e-49 177.0 COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_550383_0 1379698.RBG1_1C00001G1639 2.224e-75 265.0 COG0142@1|root,COG0142@2|Bacteria,2NP7G@2323|unclassified Bacteria 2|Bacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 - R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt SRR21617311_k127_564251_0 1379698.RBG1_1C00001G0807 7.094e-195 644.0 COG2706@1|root,COG2706@2|Bacteria,2NR81@2323|unclassified Bacteria 2|Bacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - Big_5,VCBS SRR21617311_k127_564251_3 1379698.RBG1_1C00001G0428 1.28e-22 115.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - ko:K20952 ko05111,map05111 - - - ko00000,ko00001 - - - B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS SRR21617311_k127_564251_1 1379698.RBG1_1C00001G1486 4.753e-51 192.0 COG1385@1|root,COG1385@2|Bacteria,2NPYU@2323|unclassified Bacteria 2|Bacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA SRR21617311_k127_564251_2 521098.Aaci_1994 2.516e-23 104.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,278D7@186823|Alicyclobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA SRR21617311_k127_565228_0 1379698.RBG1_1C00001G1225 5.571e-234 742.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 - - - S1 SRR21617311_k127_565228_2 1459636.NTE_03052 3.843e-48 177.0 COG0346@1|root,arCOG02708@2157|Archaea 2157|Archaea E COG0346 Lactoylglutathione lyase and related lyases - - - ko:K07032 - - - - ko00000 - - - Glyoxalase SRR21617311_k127_565228_1 1379698.RBG1_1C00001G0272 5.1e-60 213.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1,DUF2505 SRR21617311_k127_576671_3 1379698.RBG1_1C00001G0987 4.348e-41 158.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02481,ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR21617311_k127_576671_1 1379698.RBG1_1C00001G0990 8.272e-60 225.0 COG3359@1|root,COG3359@2|Bacteria,2NPCP@2323|unclassified Bacteria 2|Bacteria L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 SRR21617311_k127_576671_5 521011.Mpal_2732 2.497e-11 75.0 COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota 28890|Euryarchaeota T PBS lyase HEAT domain protein repeat-containing protein - - - ko:K22221 - - - - ko00000 - - - HEAT_2,HEAT_PBS,NACHT SRR21617311_k127_576671_0 1379698.RBG1_1C00001G0988 5.585e-173 565.0 COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria 2|Bacteria C lyase activity - - 3.4.24.3 ko:K01387,ko:K03301 - - - - ko00000,ko01000,ko01002,ko02042 2.A.12 - - DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase SRR21617311_k127_576671_4 1379698.RBG1_1C00001G1312 1.513e-37 151.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity plnP - - ko:K07052 - - - - ko00000 - - - Abi SRR21617311_k127_576671_2 1239962.C943_00706 3.748e-54 209.0 COG2866@1|root,COG2866@2|Bacteria,4NH4I@976|Bacteroidetes,47MEA@768503|Cytophagia 976|Bacteroidetes E Zn_pept - - - - - - - - - - - - Peptidase_M14 SRR21617311_k127_577154_0 1379698.RBG1_1C00001G1459 1.279e-166 529.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_577154_4 868595.Desca_2639 3.273e-13 74.0 2DNS7@1|root,32YWC@2|Bacteria,1VAUX@1239|Firmicutes 1239|Firmicutes S S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP SRR21617311_k127_577154_1 1379698.RBG1_1C00001G1458 1.233e-151 489.0 COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria 2|Bacteria I Dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SRR21617311_k127_577154_2 1379698.RBG1_1C00001G1457 1.351e-128 421.0 COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria 2|Bacteria I Dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SRR21617311_k127_577154_3 1128421.JAGA01000001_gene2171 4.717e-106 351.0 COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria 2|Bacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 SRR21617311_k127_59046_1 1382306.JNIM01000001_gene239 1.226e-26 115.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity ysfE - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234 ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100 M00127 R02530,R03471,R04509,R04734 RC00002,RC00004,RC00017,RC00740,RC01208 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase SRR21617311_k127_59046_0 1379698.RBG1_1C00001G0761 1.104e-74 257.0 COG0008@1|root,COG0008@2|Bacteria,2NNMZ@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SRR21617311_k127_592593_1 1379698.RBG1_1C00001G1647 2.692e-39 151.0 COG0673@1|root,COG0673@2|Bacteria,2NNUQ@2323|unclassified Bacteria 2|Bacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA SRR21617311_k127_592593_3 1379698.RBG1_1C00001G1646 6.799e-21 94.0 COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria 2|Bacteria I Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB SRR21617311_k127_592593_0 1379698.RBG1_1C00001G1646 8.334e-77 267.0 COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria 2|Bacteria I Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB SRR21617311_k127_592593_2 1379698.RBG1_1C00001G1644 7.014e-38 149.0 COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria 2|Bacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) lpxK - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,LpxK SRR21617311_k127_617220_1 1379698.RBG1_1C00001G0486 5.147e-83 286.0 COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria 2|Bacteria J S-adenosylmethionine-dependent methyltransferase rlmI - 2.1.1.173,2.1.1.191,2.1.1.264,2.1.1.72 ko:K00571,ko:K06969,ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko02048,ko03009 - - - Methyltrans_SAM SRR21617311_k127_617220_0 1379698.RBG1_1C00001G0485 9.33e-107 355.0 COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria 2|Bacteria C Electron transfer flavoprotein fixB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 ko:K03522,ko:K22432 - - - - ko00000,ko01000,ko04147 - - iAF987.Gmet_2066,iAF987.Gmet_2257 ETF,ETF_alpha,Fer4 SRR21617311_k127_617220_2 1379698.RBG1_1C00001G0484 3.829e-73 254.0 COG1641@1|root,COG1641@2|Bacteria,2NNX0@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF111 larC - 4.99.1.12 ko:K06898,ko:K09121 - - - - ko00000,ko01000 - - - DUF111 SRR21617311_k127_627719_2 1499967.BAYZ01000080_gene910 9.385e-08 57.0 COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2NRZP@2323|unclassified Bacteria 2|Bacteria M Hep Hag repeat protein - - - - - - - - - - - - Big_5,ESPR,LVIVD,YadA_anchor,YadA_head,YadA_stalk SRR21617311_k127_627719_0 926550.CLDAP_26360 2.738e-63 235.0 COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi 200795|Chloroflexi UW Hep Hag repeat protein - - - - - - - - - - - - - SRR21617311_k127_627719_1 204669.Acid345_1334 9.084e-30 122.0 COG5295@1|root,COG5295@2|Bacteria,3Y72W@57723|Acidobacteria,2JM9T@204432|Acidobacteriia 2|Bacteria UW Hep Hag repeat protein yeeJ - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF5122,Peptidase_S74,YadA_head,YadA_stalk SRR21617311_k127_630136_0 1379698.RBG1_1C00001G1743 2.842e-180 570.0 COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria 2|Bacteria NU Type II secretion system (T2SS), protein E, N-terminal domain pilB - - ko:K02454,ko:K02504,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N SRR21617311_k127_630136_1 945713.IALB_0757 1.562e-124 435.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec SRR21617311_k127_630136_2 1191523.MROS_0285 1.403e-49 190.0 2E09V@1|root,32VXB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_637281_4 105559.Nwat_0994 5.32e-22 101.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S479@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - FG-GAP SRR21617311_k127_637281_0 1047013.AQSP01000052_gene2600 7.601e-104 346.0 COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4162) natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SRR21617311_k127_637281_1 1047013.AQSP01000052_gene2599 7.445e-70 254.0 COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria 2|Bacteria CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SRR21617311_k127_637281_3 498761.HM1_0800 2.277e-48 179.0 COG1432@1|root,COG1432@2|Bacteria,1V1JD@1239|Firmicutes,24V8S@186801|Clostridia 186801|Clostridia S NYN domain - - - - - - - - - - - - NYN SRR21617311_k127_637281_5 1379698.RBG1_1C00001G1012 3.841e-21 97.0 COG1314@1|root,COG1314@2|Bacteria,2NQ7S@2323|unclassified Bacteria 2|Bacteria U Preprotein translocase SecG subunit secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG SRR21617311_k127_637281_2 1191523.MROS_1843 2.872e-55 199.0 COG0149@1|root,COG0149@2|Bacteria 2|Bacteria G triose-phosphate isomerase activity tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM SRR21617311_k127_644701_1 552811.Dehly_0247 1.146e-64 225.0 COG0309@1|root,COG0309@2|Bacteria,2G7TM@200795|Chloroflexi,34CX4@301297|Dehalococcoidia 301297|Dehalococcoidia O AIR synthase related protein, C-terminal domain - - - - - - - - - - - - AIRS,AIRS_C SRR21617311_k127_644701_0 264732.Moth_1652 5.272e-142 460.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales 186801|Clostridia H Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SRR21617311_k127_644701_2 1229172.JQFA01000004_gene1626 5.414e-38 148.0 COG0702@1|root,COG0702@2|Bacteria,1G3PB@1117|Cyanobacteria,1HA8X@1150|Oscillatoriales 1117|Cyanobacteria GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 SRR21617311_k127_651080_1 671143.DAMO_2060 1.179e-07 53.0 COG0816@1|root,COG0816@2|Bacteria,2NPSR@2323|unclassified Bacteria 2|Bacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX SRR21617311_k127_651080_0 290397.Adeh_0307 2.894e-77 272.0 COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria 1224|Proteobacteria S major pilin protein fima MA20_16755 - - - - - - - - - - - DUF1028 SRR21617311_k127_656356_0 1379698.RBG1_1C00001G0822 1.104e-74 257.0 COG0580@1|root,COG0580@2|Bacteria,2NQ7N@2323|unclassified Bacteria 2|Bacteria U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440,ko:K06188,ko:K09874 - - - - ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.12,1.A.8.2 - - MIP SRR21617311_k127_656356_3 1123261.AXDW01000023_gene3556 7.089e-13 77.0 COG2885@1|root,COG2885@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 1224|Proteobacteria M Belongs to the ompA family - - - - - - - - - - - - OmpA SRR21617311_k127_656356_1 485913.Krac_11442 1.885e-45 174.0 COG0580@1|root,COG0580@2|Bacteria 2|Bacteria U water channel activity glpF - - ko:K02440,ko:K06188,ko:K09874 - - - - ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.12,1.A.8.2 - - MIP SRR21617311_k127_65727_2 1122947.FR7_3296 7.499e-37 147.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4H4JF@909932|Negativicutes 909932|Negativicutes L RNA methyltransferase RsmD family rsmD - - - - - - - - - - - Cons_hypoth95 SRR21617311_k127_65727_1 1379698.RBG1_1C00001G0439 1.062e-57 208.0 COG0669@1|root,COG0669@2|Bacteria,2NPDV@2323|unclassified Bacteria 2|Bacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SRR21617311_k127_65727_0 1379698.RBG1_1C00001G1218 1.47e-282 884.0 COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria 2|Bacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase,TPR_8 SRR21617311_k127_660121_2 671143.DAMO_1830 5.883e-30 138.0 COG0745@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria 2|Bacteria T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology nifL - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1 SRR21617311_k127_660121_0 1379698.RBG1_1C00001G0796 5.244e-71 243.0 COG1956@1|root,COG1956@2|Bacteria 2|Bacteria T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF,GAF_2 SRR21617311_k127_660121_1 1379698.RBG1_1C00001G0797 3.099e-62 223.0 COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg SRR21617311_k127_663105_1 1379698.RBG1_1C00001G0682 1.61e-78 273.0 COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - ko:K20306 - - - - ko00000,ko04131 - - - Lipase_GDSL,Lipase_GDSL_2 SRR21617311_k127_663105_3 1191523.MROS_1643 1.446e-11 66.0 2EGPU@1|root,33AFZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_663105_0 1379698.RBG1_1C00001G0679 1.91e-255 800.0 COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria 2|Bacteria O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N SRR21617311_k127_663105_2 1379698.RBG1_1C00001G0678 3.598e-15 78.0 294GU@1|root,2ZRWK@2|Bacteria,2NRXQ@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_664068_1 1379698.RBG1_1C00001G0535 1.53e-76 265.0 COG0266@1|root,COG0266@2|Bacteria,2NPGY@2323|unclassified Bacteria 2|Bacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SRR21617311_k127_664068_4 1379698.RBG1_1C00001G0604 1.499e-18 92.0 COG5652@1|root,COG5652@2|Bacteria,2NRYG@2323|unclassified Bacteria 2|Bacteria S VanZ like family - - - - - - - - - - - - VanZ SRR21617311_k127_664068_0 1379698.RBG1_1C00001G1834 9.203e-103 341.0 COG1028@1|root,COG1028@2|Bacteria,2NQVI@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR21617311_k127_664068_2 1379698.RBG1_1C00001G1285 3.265e-59 210.0 COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria 2|Bacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SRR21617311_k127_664068_3 1234364.AMSF01000061_gene2084 2.988e-57 222.0 COG0793@1|root,COG0793@2|Bacteria,1N4T9@1224|Proteobacteria,1SE36@1236|Gammaproteobacteria,1X70X@135614|Xanthomonadales 135614|Xanthomonadales M Aspartyl protease - - - - - - - - - - - - Asp_protease_2,PDZ_2 SRR21617311_k127_667186_1 555079.Toce_0765 1.276e-30 122.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,42GQM@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 SRR21617311_k127_667186_2 406818.XBJ1_3855 5.104e-26 115.0 COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate elbB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - - - - - - - - - - DJ-1_PfpI SRR21617311_k127_667186_0 926569.ANT_07380 6.056e-141 458.0 COG1321@1|root,COG1914@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1914@2|Bacteria,COG1918@2|Bacteria,2G67K@200795|Chloroflexi 200795|Chloroflexi P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp SRR21617311_k127_671545_1 1379698.RBG1_1C00001G0810 1.113e-46 171.0 COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria 2|Bacteria S Methyltransferase domain yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 SRR21617311_k127_671545_0 1379698.RBG1_1C00001G0812 2.91e-86 290.0 COG0177@1|root,COG0177@2|Bacteria,2NPBI@2323|unclassified Bacteria 2|Bacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD SRR21617311_k127_671545_2 1379698.RBG1_1C00001G0813 1.412e-13 73.0 COG0667@1|root,COG0667@2|Bacteria 2|Bacteria C Aldo Keto reductase - - - ko:K07079 - - - - ko00000 - - - Aldo_ket_red SRR21617311_k127_674462_2 518766.Rmar_1872 2.978e-67 235.0 COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N SRR21617311_k127_674462_0 1379698.RBG1_1C00001G0968 1.14e-212 670.0 COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GatB_N,GatB_Yqey SRR21617311_k127_674462_1 1379698.RBG1_1C00001G0966 7.091e-178 571.0 COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase SRR21617311_k127_674462_3 1379698.RBG1_1C00001G1762 1.21e-15 79.0 COG3276@1|root,COG3276@2|Bacteria,2NNQU@2323|unclassified Bacteria 2|Bacteria J Elongation factor SelB, winged helix selB GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 SRR21617311_k127_675784_3 330214.NIDE0884 1.883e-39 152.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase rhiI GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - ko:K15471 - - - - ko00000,ko01000,ko01008 - - - Methyltransf_11,Methyltransf_25 SRR21617311_k127_675784_1 768704.Desmer_4328 3.179e-134 438.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae 186801|Clostridia E Belongs to the DegT DnrJ EryC1 family spsC - - - - - - - - - - - DegT_DnrJ_EryC1 SRR21617311_k127_675784_0 1089553.Tph_c02680 1.388e-159 531.0 COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42EJW@68295|Thermoanaerobacterales 186801|Clostridia GM PFAM Polysaccharide biosynthesis protein epsC - - - - - - - - - - - CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2 SRR21617311_k127_675784_2 1379698.RBG1_1C00001G1543 1.189e-117 396.0 COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SRR21617311_k127_677605_1 1379698.RBG1_1C00001G1140 4.094e-57 205.0 COG0324@1|root,COG0324@2|Bacteria,2NP6D@2323|unclassified Bacteria 2|Bacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT SRR21617311_k127_677605_0 1379698.RBG1_1C00001G1141 1.047e-105 361.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria 2|Bacteria M Transglycosylase SLT domain CP_0155 - - ko:K08307,ko:K12204 - - - - ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,SLT,T4SS_TraI SRR21617311_k127_692826_0 1379698.RBG1_1C00001G0210 9.56e-142 460.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.2,3.6.1.27 ko:K09474,ko:K19302 ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020 - R00548,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 SRR21617311_k127_692826_1 1121468.AUBR01000025_gene2988 2.291e-120 397.0 COG3177@1|root,COG3177@2|Bacteria,1TV5J@1239|Firmicutes,24CRC@186801|Clostridia 186801|Clostridia S PFAM Fic DOC family - - - - - - - - - - - - Fic,Fic_N,HTH_24,TrmB SRR21617311_k127_697022_3 1379698.RBG1_1C00001G0876 5.472e-141 456.0 COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria 2|Bacteria E Aminotransferase aspC - 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SRR21617311_k127_697022_1 1379698.RBG1_1C00001G0875 4.225e-153 488.0 COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria 2|Bacteria G Transketolase, pyrimidine binding domain tktC - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SRR21617311_k127_697022_2 1379698.RBG1_1C00001G0874 5.173e-145 464.0 COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria 2|Bacteria G Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N SRR21617311_k127_697022_4 1379698.RBG1_1C00001G0873 9.263e-51 188.0 COG0237@1|root,COG0237@2|Bacteria,2NPMB@2323|unclassified Bacteria 2|Bacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 ko:K00859,ko:K07566 ko00770,ko01100,map00770,map01100 M00120 R00130,R10463 RC00002,RC00078,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 - - - CoaE SRR21617311_k127_697022_0 1379698.RBG1_1C00001G0871 9.934e-239 753.0 COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SRR21617311_k127_69820_1 1379698.RBG1_1C00001G0103 5.372e-277 870.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 SRR21617311_k127_69820_4 1379698.RBG1_1C00001G0104 3.366e-61 213.0 COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria 2|Bacteria T Transcriptional regulator, TraR DksA family dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR SRR21617311_k127_69820_5 1379698.RBG1_1C00001G0105 6.654e-42 160.0 COG0597@1|root,COG0597@2|Bacteria,2NPU1@2323|unclassified Bacteria 2|Bacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 SRR21617311_k127_69820_3 246194.CHY_1505 9.068e-82 283.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales 186801|Clostridia J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SRR21617311_k127_69820_2 1379698.RBG1_1C00001G0110 2.536e-163 525.0 COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria 2|Bacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1383 CPSase_sm_chain,GATase SRR21617311_k127_69820_0 1379698.RBG1_1C00001G0111 3.536e-279 871.0 COG0458@1|root,COG0458@2|Bacteria,2NNPB@2323|unclassified Bacteria 2|Bacteria EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS SRR21617311_k127_703793_0 697281.Mahau_1477 6.804e-133 432.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,42ER3@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SRR21617311_k127_703793_3 498761.HM1_2282 3.296e-42 165.0 COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,1V7I1@1239|Firmicutes,24GQ3@186801|Clostridia 186801|Clostridia I Integral membrane protein DUF92 - - - - - - - - - - - - DUF92 SRR21617311_k127_703793_2 404589.Anae109_2548 5.306e-57 224.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales 28221|Deltaproteobacteria S Putative glutamine amidotransferase - - - - - - - - - - - - GATase1_like SRR21617311_k127_703793_1 1379698.RBG1_1C00001G1639 6.76e-87 297.0 COG0142@1|root,COG0142@2|Bacteria,2NP7G@2323|unclassified Bacteria 2|Bacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 - R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt SRR21617311_k127_703928_0 1379698.RBG1_1C00001G0517 2.206e-213 670.0 COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria 2|Bacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SRR21617311_k127_703928_1 91464.S7335_3871 3.468e-07 55.0 COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria 1117|Cyanobacteria S sulfuric ester hydrolase activity - - - - - - - - - - - - - SRR21617311_k127_71992_0 1379698.RBG1_1C00001G0231 6.199e-64 239.0 COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria 2|Bacteria C HEAT repeats CP_0755 - - - - - - - - - - - HEAT_2,HEAT_PBS,Response_reg SRR21617311_k127_720347_1 69781.S8BH90 1.821e-05 53.0 2CZ1E@1|root,2S7T1@2759|Eukaryota,3A3ZM@33154|Opisthokonta,3P4JR@4751|Fungi,3QW3R@4890|Ascomycota,20I3D@147545|Eurotiomycetes,3S933@5042|Eurotiales 4751|Fungi S Disease resistance protein Aig2 - - - - - - - - - - - - GGACT SRR21617311_k127_720347_0 1379698.RBG1_1C00001G0804 2.008e-46 170.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_727064_0 1379698.RBG1_1C00001G1833 2.695e-34 134.0 COG1379@1|root,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria 2|Bacteria L DNA helicase yqxK - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4178,PHP_C,UvrD-helicase,UvrD_C SRR21617311_k127_727064_1 1173027.Mic7113_1777 7.639e-07 61.0 COG1196@1|root,COG4677@1|root,COG1196@2|Bacteria,COG4677@2|Bacteria,1GR7B@1117|Cyanobacteria,1HI9P@1150|Oscillatoriales 1117|Cyanobacteria G Pectinesterase - - - - - - - - - - - - Beta_helix SRR21617311_k127_729962_1 326424.FRAAL2823 3.921e-10 63.0 COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria 201174|Actinobacteria S Activator of hsp90 atpase 1 family protein - - - - - - - - - - - - AHSA1 SRR21617311_k127_729962_0 673860.AciM339_1039 8.277e-140 458.0 COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,3F2G3@33867|unclassified Euryarchaeota 28890|Euryarchaeota E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.114,4.2.1.33,4.2.1.35 ko:K01703,ko:K16792 ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230 M00432,M00433,M00535,M00608 R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396 RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase SRR21617311_k127_742541_1 2325.TKV_c05660 7.452e-15 75.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,42FF8@68295|Thermoanaerobacterales 186801|Clostridia S PFAM Xanthine uracil vitamin C permease - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease SRR21617311_k127_742541_0 1379698.RBG1_1C00001G0733 2.881e-76 277.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_755207_0 1379698.RBG1_1C00001G1025 2.769e-104 347.0 COG0322@1|root,COG0322@2|Bacteria,2NNQ4@2323|unclassified Bacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N SRR21617311_k127_755207_1 1379698.RBG1_1C00001G1027 1.823e-65 230.0 COG0491@1|root,COG0491@2|Bacteria,2NPD5@2323|unclassified Bacteria 2|Bacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SRR21617311_k127_757071_0 1121468.AUBR01000017_gene2358 7.531e-110 364.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N SRR21617311_k127_757071_2 1401067.HMPREF0872_08050 2.662e-13 72.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes 909932|Negativicutes F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N SRR21617311_k127_757071_1 1410638.JHXJ01000030_gene275 6.925e-39 150.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae 186801|Clostridia F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC SRR21617311_k127_757071_3 404380.Gbem_2645 1.883e-08 65.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,43U1H@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 SRR21617311_k127_771278_0 1379698.RBG1_1C00001G0608 1.589e-155 510.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N SRR21617311_k127_773777_0 1379698.RBG1_1C00001G1599 4.719e-233 724.0 COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria 2|Bacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - iSB619.SA_RS02960 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SRR21617311_k127_773777_7 1123325.JHUV01000003_gene1570 2.588e-17 81.0 COG0267@1|root,COG0267@2|Bacteria,2G493@200783|Aquificae 200783|Aquificae J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 SRR21617311_k127_773777_8 518766.Rmar_1102 1.007e-06 54.0 COG0690@1|root,COG0690@2|Bacteria,4PEVK@976|Bacteroidetes,1FJPC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE SRR21617311_k127_773777_3 1379698.RBG1_1C00001G1610 4.047e-73 250.0 COG0250@1|root,COG0250@2|Bacteria,2NPAP@2323|unclassified Bacteria 2|Bacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG SRR21617311_k127_773777_4 1379698.RBG1_1C00001G1609 2.707e-65 226.0 COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria 2|Bacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N SRR21617311_k127_773777_2 1379698.RBG1_1C00001G1608 3.126e-103 340.0 COG0081@1|root,COG0081@2|Bacteria,2NNK6@2323|unclassified Bacteria 2|Bacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 SRR21617311_k127_773777_6 880073.Calab_2117 6.104e-37 146.0 COG0244@1|root,COG0244@2|Bacteria,2NPYE@2323|unclassified Bacteria 2|Bacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 SRR21617311_k127_773777_5 1379698.RBG1_1C00001G1606 2.736e-43 161.0 COG0222@1|root,COG0222@2|Bacteria,2NPJ4@2323|unclassified Bacteria 2|Bacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N SRR21617311_k127_773777_1 880073.Calab_2119 4.654e-148 481.0 COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 SRR21617311_k127_782100_1 1379698.RBG1_1C00001G1084 1.917e-92 306.0 COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria 2|Bacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase SRR21617311_k127_782100_3 1382356.JQMP01000001_gene991 1.017e-17 96.0 COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia 189775|Thermomicrobia U Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SRR21617311_k127_782100_0 1379698.RBG1_1C00001G1421 3.636e-93 331.0 COG4191@1|root,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria 2|Bacteria T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS_4,PAS_8,PAS_9,Response_reg SRR21617311_k127_782100_2 1379698.RBG1_1C00001G1223 3.437e-27 111.0 COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria 2|Bacteria E FAD dependent oxidoreductase - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO SRR21617311_k127_788162_0 1121481.AUAS01000006_gene877 2.185e-57 216.0 COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia 976|Bacteroidetes Q SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - CHU_C,FG-GAP,HYR,VCBS SRR21617311_k127_806720_0 1379698.RBG1_1C00001G1523 4.016e-117 391.0 COG4775@1|root,COG4775@2|Bacteria,2NQXR@2323|unclassified Bacteria 2|Bacteria M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SRR21617311_k127_806720_1 1379698.RBG1_1C00001G1522 4.648e-63 224.0 COG2071@1|root,COG2071@2|Bacteria,2NPQK@2323|unclassified Bacteria 2|Bacteria S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 SRR21617311_k127_806720_2 1121430.JMLG01000025_gene95 6.466e-47 177.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,261I7@186807|Peptococcaceae 186801|Clostridia H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI SRR21617311_k127_812362_3 1379698.RBG1_1C00001G0777 1.908e-19 89.0 COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria 2|Bacteria P Prokaryotic cytochrome b561 cbcY - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese SRR21617311_k127_812362_0 1379698.RBG1_1C00001G0778 8.65e-233 730.0 COG3005@1|root,COG3005@2|Bacteria,2NQ9M@2323|unclassified Bacteria 2|Bacteria C NapC/NirT cytochrome c family, N-terminal region - - - - - - - - - - - - Cytochrom_NNT,Cytochrom_c3_2 SRR21617311_k127_812362_2 1379698.RBG1_1C00001G0779 8.226e-135 441.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB SRR21617311_k127_812362_1 1379698.RBG1_1C00001G0780 5.514e-149 478.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B SRR21617311_k127_812729_0 1379698.RBG1_1C00001G0426 9.987e-118 388.0 2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_812729_1 1392487.JIAD01000001_gene754 1.038e-09 60.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,25UYP@186806|Eubacteriaceae 186801|Clostridia H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - ACPS,Carb_kinase,YjeF_N SRR21617311_k127_825518_0 1162668.LFE_2206 7.967e-139 448.0 COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae 40117|Nitrospirae H Galactose-1-phosphate uridyl transferase, N-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf SRR21617311_k127_825518_1 1379698.RBG1_1C00001G1107 7.908e-93 312.0 COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria 2|Bacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_4 SRR21617311_k127_829330_3 518766.Rmar_1232 5.46e-06 48.0 COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,4NS7V@976|Bacteroidetes 976|Bacteroidetes L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 SRR21617311_k127_829330_0 1379698.RBG1_1C00001G1395 9.728e-160 511.0 28IS3@1|root,2Z8R9@2|Bacteria 2|Bacteria S Psort location Cytoplasmic, score - - - - - - - - - - - - Phage_capsid SRR21617311_k127_829442_1 1379698.RBG1_1C00001G1319 1.294e-133 438.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR21617311_k127_829442_2 1379698.RBG1_1C00001G1318 1.031e-70 251.0 COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria 2|Bacteria S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SRR21617311_k127_829442_0 1379698.RBG1_1C00001G1252 7.79e-146 470.0 COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria 2|Bacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8,5.4.2.8 ko:K00971,ko:K01840,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01818,R01819 RC00002,RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00940 MannoseP_isomer,NTP_transferase SRR21617311_k127_829442_3 1125863.JAFN01000001_gene2042 2.84e-28 124.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Sua5 YciO YrdC YwlC family protein yrdC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC SRR21617311_k127_829442_4 429009.Adeg_0069 6.465e-27 115.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales 186801|Clostridia T PFAM Protein-tyrosine phosphatase, low molecular weight ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc SRR21617311_k127_830717_0 635013.TherJR_1075 2.192e-80 282.0 COG2856@1|root,COG2944@1|root,COG2856@2|Bacteria,COG2944@2|Bacteria,1TQAC@1239|Firmicutes,24AMH@186801|Clostridia 186801|Clostridia E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 SRR21617311_k127_830717_4 114615.BRADO6391 2.204e-28 121.0 COG1439@1|root,COG1439@2|Bacteria,1Q0CP@1224|Proteobacteria,2USMZ@28211|Alphaproteobacteria,3K401@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4411) - - - - - - - - - - - - DUF4411 SRR21617311_k127_830717_2 251221.35212829 9.907e-58 220.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - CBM9_1,CBM_6 SRR21617311_k127_830717_1 1379698.RBG1_1C00001G0713 9.871e-67 235.0 COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria 2|Bacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short SRR21617311_k127_830717_6 1123319.AUBE01000031_gene5059 0.0009052 49.0 COG1316@1|root,COG1316@2|Bacteria,2H6VU@201174|Actinobacteria 201174|Actinobacteria K LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C SRR21617311_k127_831131_1 1379698.RBG1_1C00001G1535 5.643e-44 166.0 COG0253@1|root,COG0253@2|Bacteria,2NPFA@2323|unclassified Bacteria 2|Bacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase SRR21617311_k127_831131_2 1379698.RBG1_1C00001G0155 1.318e-42 161.0 COG0355@1|root,COG0355@2|Bacteria,2NPSQ@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 ATP-synt_DE,ATP-synt_DE_N SRR21617311_k127_831131_0 1379698.RBG1_1C00001G0153 6.142e-250 775.0 COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N SRR21617311_k127_833993_1 1379698.RBG1_1C00001G1188 5.362e-62 220.0 COG1321@1|root,COG1321@2|Bacteria,2NRDQ@2323|unclassified Bacteria 2|Bacteria K FeoA sirR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SRR21617311_k127_833993_3 1121456.ATVA01000017_gene121 2.143e-35 154.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales 28221|Deltaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SRR21617311_k127_833993_0 1303518.CCALI_00475 1.792e-107 352.0 COG0479@1|root,COG0479@2|Bacteria 2|Bacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB1 - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0247c Fer2_3,Fer4_8 SRR21617311_k127_833993_2 1303518.CCALI_00474 5.605e-43 164.0 COG1053@1|root,COG1053@2|Bacteria 2|Bacteria C succinate dehydrogenase sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SRR21617311_k127_836124_4 1379698.RBG1_1C00001G0608 7.151e-10 59.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N SRR21617311_k127_836124_2 1379698.RBG1_1C00001G0861 9.752e-35 137.0 COG0735@1|root,COG0735@2|Bacteria,2NQ2N@2323|unclassified Bacteria 2|Bacteria P Belongs to the Fur family fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K03711 - - - - ko00000,ko03000 - - - FUR SRR21617311_k127_836124_0 472759.Nhal_0414 1.415e-54 207.0 COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - SRR21617311_k127_836124_3 1009370.ALO_16607 2.177e-12 70.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4H5TI@909932|Negativicutes 909932|Negativicutes P FeoA family - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA SRR21617311_k127_836124_1 1210884.HG799468_gene13632 3.146e-53 201.0 COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes 203682|Planctomycetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate SRR21617311_k127_849734_0 309801.trd_A0299 3.229e-119 396.0 COG2252@1|root,COG2252@2|Bacteria,2G7JW@200795|Chloroflexi,27XP4@189775|Thermomicrobia 189775|Thermomicrobia S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease SRR21617311_k127_849734_1 1379698.RBG1_1C00001G0505 6.869e-63 235.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SRR21617311_k127_850773_0 1379698.RBG1_1C00001G0435 1.461e-112 383.0 COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria 2|Bacteria M methyltransferase greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N,SprA_N SRR21617311_k127_852099_1 760142.Hipma_0811 2.219e-39 156.0 COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42S3A@68525|delta/epsilon subdivisions,2X6UX@28221|Deltaproteobacteria,2M6MD@213113|Desulfurellales 28221|Deltaproteobacteria F Thymidylate synthase complementing protein thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 SRR21617311_k127_852099_0 246197.MXAN_2925 8.487e-294 915.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA1 - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC SRR21617311_k127_854451_6 1128421.JAGA01000001_gene2145 5.203e-18 89.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity MA20_05735 - - - - - - - - - - - HTH_34 SRR21617311_k127_854451_2 1128421.JAGA01000001_gene2144 5.317e-62 219.0 COG3127@1|root,COG3127@2|Bacteria 2|Bacteria Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR21617311_k127_854451_3 1379698.RBG1_1C00001G1687 2.674e-51 185.0 2DNQ8@1|root,32YJ3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_854451_1 1121920.AUAU01000001_gene2168 8.711e-88 298.0 COG2519@1|root,COG2519@2|Bacteria,3Y5T2@57723|Acidobacteria 57723|Acidobacteria J Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 SRR21617311_k127_854451_4 1196323.ALKF01000203_gene3746 1.449e-47 176.0 COG3797@1|root,COG3797@2|Bacteria,1VJ1T@1239|Firmicutes,4HQ2E@91061|Bacilli,274WH@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 SRR21617311_k127_854451_8 368407.Memar_2438 3.853e-05 52.0 arCOG04662@1|root,arCOG04662@2157|Archaea,2XU93@28890|Euryarchaeota,2NBCG@224756|Methanomicrobia 224756|Methanomicrobia - - - - - - - - - - - - - - - SRR21617311_k127_854451_5 1191523.MROS_1047 5.072e-20 95.0 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_854451_7 880073.Calab_0295 3.059e-10 65.0 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG SRR21617311_k127_854451_0 247490.KSU1_C0659 1.475e-110 385.0 COG0612@1|root,COG0612@2|Bacteria,2IWSI@203682|Planctomycetes 203682|Planctomycetes S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_856571_4 1379698.RBG1_1C00001G1472 1.047e-31 126.0 COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria 2|Bacteria S Metallo-beta-lactamase superfamily ytnP - - - - - - - - - - - Lactamase_B SRR21617311_k127_856571_2 580327.Tthe_1660 2.99e-98 336.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales 186801|Clostridia C PFAM Acyl-CoA dehydrogenase bcd GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 ko:K00248,ko:K22430 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SRR21617311_k127_856571_0 671143.DAMO_0652 3.156e-227 711.0 COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR21617311_k127_856571_3 370438.PTH_1363 1.976e-39 150.0 COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia,261ZX@186807|Peptococcaceae 186801|Clostridia E PFAM Glyoxalase bleomycin resistance protein dioxygenase mce - 4.4.1.5,5.1.99.1 ko:K01759,ko:K05606 ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02530,R02765,R09979 RC00004,RC00740,RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 SRR21617311_k127_856571_1 1379698.RBG1_1C00001G1468 8.21e-133 430.0 COG1884@1|root,COG1884@2|Bacteria,2NNP5@2323|unclassified Bacteria 2|Bacteria I Methylmalonyl-CoA mutase bhbA - 5.4.99.2 ko:K01847,ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase SRR21617311_k127_862781_1 1303518.CCALI_02898 3.012e-84 284.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC SRR21617311_k127_862781_2 1379698.RBG1_1C00001G0766 5.654e-39 155.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - ko:K12057 - - - - ko00000,ko02044 3.A.7.11.1 - - AhpC-TSA,DUF4369,Thioredoxin_8,TraF SRR21617311_k127_862781_0 1379698.RBG1_1C00001G0765 1.431e-159 509.0 COG2132@1|root,COG2132@2|Bacteria,2NPCW@2323|unclassified Bacteria 2|Bacteria PQ Multicopper oxidase aniA - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 SRR21617311_k127_871797_4 498761.HM1_1313 5.111e-27 113.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia 186801|Clostridia G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - iHN637.CLJU_RS19265 TIM SRR21617311_k127_871797_0 945713.IALB_1271 5.842e-157 504.0 COG0126@1|root,COG0126@2|Bacteria 2|Bacteria F phosphoglycerate kinase activity pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK SRR21617311_k127_871797_1 1379698.RBG1_1C00001G1009 1.4e-147 474.0 COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria 2|Bacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0022610,GO:0030246,GO:0030247,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:2001065 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iJR904.b1416,iJR904.b1417 Gp_dh_C,Gp_dh_N SRR21617311_k127_871797_3 351160.RCIX924 2.899e-31 132.0 COG1011@1|root,arCOG02291@2157|Archaea 2157|Archaea S hydrolase (HAD superfamily) - - - ko:K07025 - - - - ko00000 - - - HAD_2 SRR21617311_k127_871797_2 945713.IALB_0831 3.946e-60 230.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_2,GAF_3,SpoIIE SRR21617311_k127_872264_0 1379698.RBG1_1C00001G0230 3.182e-122 409.0 COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria 2|Bacteria T Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD SRR21617311_k127_872264_1 1128427.KB904821_gene3113 2.927e-07 57.0 COG2217@1|root,COG2217@2|Bacteria,1G05S@1117|Cyanobacteria,1H715@1150|Oscillatoriales 1117|Cyanobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC zntA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase SRR21617311_k127_882655_0 1379698.RBG1_1C00001G0054 8.349e-229 710.0 COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria 2|Bacteria E Aspartate-ammonia ligase asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 AsnA SRR21617311_k127_882655_1 234267.Acid_6967 3.921e-108 358.0 COG1131@1|root,COG1131@2|Bacteria,3Y78D@57723|Acidobacteria 57723|Acidobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR21617311_k127_882655_2 1382356.JQMP01000003_gene1542 4.557e-71 250.0 COG0842@1|root,COG0842@2|Bacteria,2G9U5@200795|Chloroflexi,27Z6S@189775|Thermomicrobia 189775|Thermomicrobia V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SRR21617311_k127_882655_4 1349785.BAUG01000028_gene1680 2.531e-15 81.0 COG2259@1|root,COG2259@2|Bacteria,4NVWM@976|Bacteroidetes,1I5GY@117743|Flavobacteriia 976|Bacteroidetes S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SRR21617311_k127_882655_3 1379698.RBG1_1C00001G0625 2.236e-22 102.0 COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria 2|Bacteria S Vault protein inter-alpha-trypsin domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - FecR,VIT,VWA,VWA_3 SRR21617311_k127_893958_0 1379698.RBG1_1C00001G0602 6.814e-78 265.0 COG0842@1|root,COG0842@2|Bacteria,2NQCU@2323|unclassified Bacteria 2|Bacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SRR21617311_k127_893958_1 927658.AJUM01000034_gene524 4.667e-05 52.0 COG4912@1|root,COG4912@2|Bacteria,4NHAJ@976|Bacteroidetes,2G32T@200643|Bacteroidia 976|Bacteroidetes L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation SRR21617311_k127_896587_6 1232447.BAHW02000019_gene1257 0.0002447 49.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,268GS@186813|unclassified Clostridiales 186801|Clostridia J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N SRR21617311_k127_896587_2 1379698.RBG1_1C00001G1152 1.595e-146 477.0 COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria 2|Bacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 SRR21617311_k127_896587_5 309799.DICTH_1080 3.452e-25 111.0 COG0779@1|root,COG0779@2|Bacteria 2|Bacteria S ribosomal small subunit biogenesis rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C SRR21617311_k127_896587_0 1379698.RBG1_1C00001G1150 2.678e-246 772.0 COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN678.proS,iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit SRR21617311_k127_896587_1 1379698.RBG1_1C00001G0798 4.463e-233 749.0 COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria 2|Bacteria E aminopeptidase pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - HEAT_2,Peptidase_M1 SRR21617311_k127_896587_3 1379698.RBG1_1C00001G1144 5.649e-44 165.0 COG0622@1|root,COG0622@2|Bacteria,2NQ04@2323|unclassified Bacteria 2|Bacteria S Calcineurin-like phosphoesterase superfamily domain ysnB - - ko:K07095 - - - - ko00000 - - - Metallophos_2 SRR21617311_k127_896587_4 1379698.RBG1_1C00001G1143 4.461e-43 158.0 COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria 2|Bacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup_1 - - ko:K03530,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SRR21617311_k127_898484_0 1379698.RBG1_1C00001G1656 0.0 1016.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW SRR21617311_k127_900105_0 1379698.RBG1_1C00001G0637 7.87e-200 630.0 COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria 2|Bacteria M UDP binding domain - - 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 - R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR21617311_k127_900105_1 1379698.RBG1_1C00001G0636 1.476e-88 303.0 COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein wcbK - 1.1.1.281,4.2.1.47 ko:K01711,ko:K15856 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888,R03397,R03399 RC00182,RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SRR21617311_k127_900105_2 1379698.RBG1_1C00001G1847 5.987e-33 135.0 COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria 2|Bacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH SRR21617311_k127_90981_1 880073.Calab_0513 2.114e-43 163.0 2C3GN@1|root,31EWU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_90981_0 323261.Noc_2093 3.945e-53 203.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S479@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q SMART Integrin alpha beta-propellor repeat protein - - 3.1.4.50 ko:K01127 ko00563,map00563 - R06623 - ko00000,ko00001,ko01000 - - - FG-GAP SRR21617311_k127_90981_2 1379698.RBG1_1C00001G0698 2.331e-38 145.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria 2|Bacteria C Malic enzyme, NAD binding domain maeB GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1637 Malic_M,PTA_PTB,malic SRR21617311_k127_909910_2 1140.Synpcc7942_1337 3.097e-57 214.0 COG2273@1|root,COG2931@1|root,COG2273@2|Bacteria,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus 1117|Cyanobacteria Q Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Calx-beta,FG-GAP SRR21617311_k127_909910_4 1379698.RBG1_1C00001G0593 4.222e-22 109.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,Cadherin_3,DUF11,FlgD_ig SRR21617311_k127_909910_0 1379698.RBG1_1C00001G1193 1.269e-121 402.0 COG0006@1|root,COG0006@2|Bacteria,2NQIC@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 SRR21617311_k127_909910_1 880073.Calab_0201 3.254e-120 412.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2NNYS@2323|unclassified Bacteria 2|Bacteria L DNA polymerase III, epsilon subunit dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII SRR21617311_k127_909910_3 443144.GM21_0971 3.071e-53 198.0 COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria 28221|Deltaproteobacteria V PFAM secretion protein HlyD family protein ybhG - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SRR21617311_k127_909910_5 1449126.JQKL01000036_gene1950 2.555e-20 95.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SRR21617311_k127_915300_0 398767.Glov_0772 4.529e-51 195.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales 28221|Deltaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SRR21617311_k127_915300_1 1123008.KB905697_gene3215 9.713e-12 78.0 COG1538@1|root,COG1538@2|Bacteria,4P2W9@976|Bacteroidetes,2FXFX@200643|Bacteroidia,23040@171551|Porphyromonadaceae 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP SRR21617311_k127_937056_1 936455.KI421499_gene3001 3.203e-18 95.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8 SRR21617311_k127_937056_0 313606.M23134_05923 2.955e-33 137.0 COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, Crp Fnr family - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding SRR21617311_k127_939268_1 1379698.RBG1_1C00001G1357 6.509e-47 172.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein exbD2 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD SRR21617311_k127_939268_2 1379698.RBG1_1C00001G1356 2.094e-45 169.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein exbD1 - - - - - - - - - - - ExbD SRR21617311_k127_939268_0 1379698.RBG1_1C00001G1355 3.635e-99 328.0 COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB SRR21617311_k127_939268_3 313612.L8106_27052 5.578e-14 85.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G3KK@1117|Cyanobacteria,1HAD4@1150|Oscillatoriales 1117|Cyanobacteria O Glycosyl transferase family 41 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 SRR21617311_k127_944131_0 1379698.RBG1_1C00001G1163 1.221e-178 567.0 COG0017@1|root,COG0017@2|Bacteria,2NNQM@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class II (D, K and N) asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SRR21617311_k127_944131_2 1379698.RBG1_1C00001G1162 6.235e-55 203.0 COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria 2|Bacteria G Polysaccharide deacetylase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1 SRR21617311_k127_944131_1 1379698.RBG1_1C00001G1161 5.58e-126 412.0 COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria 2|Bacteria S Belongs to the peptidase M16 family pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_950372_0 555088.DealDRAFT_2566 8.74e-157 516.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42JKJ@68298|Syntrophomonadaceae 186801|Clostridia J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind SRR21617311_k127_950372_1 880073.Calab_1952 4.791e-62 225.0 COG1774@1|root,COG1774@2|Bacteria,2NPEB@2323|unclassified Bacteria 2|Bacteria S PSP1 C-terminal conserved region yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 SRR21617311_k127_950372_2 330214.NIDE1739 1.461e-60 220.0 COG0534@1|root,COG0534@2|Bacteria 2|Bacteria V drug transmembrane transporter activity norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE SRR21617311_k127_952196_2 401526.TcarDRAFT_1987 1.694e-09 61.0 COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes 909932|Negativicutes L AAA domain - - - - - - - - - - - - AAA_23,AAA_27 SRR21617311_k127_952196_0 1163730.FFONT_0979 5.728e-52 192.0 COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota 28889|Crenarchaeota F PFAM histidine triad (HIT) protein - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT SRR21617311_k127_952196_1 1379698.RBG1_1C00001G0179 5.343e-13 73.0 COG0065@1|root,COG0065@2|Bacteria 2|Bacteria E 3-isopropylmalate dehydratase activity - - 4.2.1.33,4.2.1.35,4.2.1.36 ko:K01703,ko:K01705 ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230 M00030,M00432,M00433,M00535 R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR21617311_k127_959531_1 1379698.RBG1_1C00001G0367 2.743e-130 429.0 COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria 2|Bacteria S Transporter associated domain ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03699,ko:K06189 - - - - ko00000,ko02000,ko02042 9.A.40.1.2 - - CBS,CorC_HlyC,DUF21,TerC SRR21617311_k127_959531_2 1123368.AUIS01000004_gene227 6.057e-74 257.0 COG0586@1|root,COG0586@2|Bacteria,1RGII@1224|Proteobacteria,1S844@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SNARE associated Golgi protein - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - SNARE_assoc SRR21617311_k127_959531_3 929556.Solca_0457 2.697e-14 79.0 2E4RV@1|root,32ZKD@2|Bacteria,4NWUE@976|Bacteroidetes,1IU9D@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_959531_0 518766.Rmar_0089 8.561e-213 684.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Peptidase M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR21617311_k127_96540_0 1379698.RBG1_1C00001G1262 2.634e-27 120.0 COG4967@1|root,COG4967@2|Bacteria 2|Bacteria NU type IV pilus modification protein PilV - - - ko:K02458,ko:K02671 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 - - N_methyl SRR21617311_k127_96540_1 1379698.RBG1_1C00001G1261 5.184e-11 71.0 COG4966@1|root,COG4966@2|Bacteria 2|Bacteria NU pilus assembly protein PilW pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW SRR21617311_k127_969852_3 1379698.RBG1_1C00001G0147 1.077e-05 47.0 COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C SRR21617311_k127_969852_1 1379698.RBG1_1C00001G0148 9.408e-51 184.0 COG0711@1|root,COG0711@2|Bacteria,2NQ34@2323|unclassified Bacteria 2|Bacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B SRR21617311_k127_969852_2 251221.35213476 1.791e-18 97.0 COG0712@1|root,COG0712@2|Bacteria,1G5SS@1117|Cyanobacteria 1117|Cyanobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP SRR21617311_k127_969852_0 1379698.RBG1_1C00001G0150 1.223e-212 664.0 COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N SRR21617311_k127_97332_1 1379698.RBG1_1C00001G1235 2.029e-07 62.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CarbopepD_reg_2 SRR21617311_k127_97332_0 1278073.MYSTI_04056 1.158e-14 77.0 COG1752@1|root,COG1752@2|Bacteria 2|Bacteria M Esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin SRR21617311_k127_976024_1 1379698.RBG1_1C00001G1887 1.656e-52 190.0 COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria 2|Bacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase SRR21617311_k127_976024_0 1379698.RBG1_1C00001G1888 2.396e-172 548.0 COG0468@1|root,COG0468@2|Bacteria,2NNYW@2323|unclassified Bacteria 2|Bacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA SRR21617311_k127_976024_2 748449.Halha_1605 1.818e-19 95.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24KZH@186801|Clostridia,3WAVE@53433|Halanaerobiales 186801|Clostridia S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX SRR21617311_k127_98023_0 1379698.RBG1_1C00001G1517 5.599e-106 351.0 COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria 2|Bacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans SRR21617311_k127_98023_1 555079.Toce_0270 2.62e-87 294.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia,42GDI@68295|Thermoanaerobacterales 186801|Clostridia S Belongs to the UPF0173 family - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 SRR21617311_k127_98023_2 1379698.RBG1_1C00001G1516 3.064e-55 210.0 COG2982@1|root,COG2982@2|Bacteria,2NRT5@2323|unclassified Bacteria 2|Bacteria M AsmA-like C-terminal region - - - ko:K07289,ko:K09800 - - - - ko00000,ko02000 - - - AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH SRR21617311_k127_982553_1 523850.TON_0527 5.569e-30 121.0 COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci 183968|Thermococci J Endoribonuclease L-PSP - GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP SRR21617311_k127_982553_0 1379698.RBG1_1C00001G0527 7.909e-158 503.0 COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria 2|Bacteria I Acyl-CoA dehydrogenase, C-terminal domain B4168_2380 - 1.3.99.32 ko:K16173 ko00362,ko01120,map00362,map01120 - R05579 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SRR21617311_k127_986503_1 1379698.RBG1_1C00001G1605 1.552e-301 936.0 COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 SRR21617311_k127_986503_2 1379698.RBG1_1C00001G1604 6.415e-212 662.0 COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 SRR21617311_k127_986503_0 1379698.RBG1_1C00001G1604 0.0 1467.0 COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 SRR21617311_k127_986503_3 1379698.RBG1_1C00001G1603 3.386e-10 60.0 COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria 2|Bacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 SRR21617311_k127_998573_1 667014.Thein_1494 2.275e-80 275.0 COG0319@1|root,COG0854@1|root,COG0319@2|Bacteria,COG0854@2|Bacteria,2GH7V@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ,UPF0054 SRR21617311_k127_998573_5 518766.Rmar_2135 1.091e-09 67.0 2E919@1|root,333AJ@2|Bacteria,4P65A@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SRR21617311_k127_998573_4 518766.Rmar_0713 3.361e-11 72.0 2EGU2@1|root,33AK8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR21617311_k127_998573_3 500635.MITSMUL_04410 1.009e-52 197.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4H210@909932|Negativicutes 909932|Negativicutes J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SRR21617311_k127_998573_2 1379698.RBG1_1C00001G0319 1.123e-69 245.0 COG0084@1|root,COG0084@2|Bacteria,2NP9H@2323|unclassified Bacteria 2|Bacteria L TatD related DNase tatD GO:0000175,GO:0000302,GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009056,GO:0009057,GO:0009636,GO:0009987,GO:0010035,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046700,GO:0046872,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901700 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SRR21617311_k127_998573_0 1379698.RBG1_1C00001G0317 3.184e-116 385.0 COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria 2|Bacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind ## 2083 queries scanned ## Total time (seconds): 6.5948967933654785 ## Rate: 315.85 q/s