## Tue Dec 16 01:51:38 2025 ## emapper-2.1.13 ## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR34280931_bin.3.fa -m mmseqs --itype genome -o SRR34280931_bin.3 --output_dir /data/result/bins/wyx/egg/SRR34280931_bin.3 --cpu 32 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs SRR34280931_k127_1031295_3 1304888.ATWF01000001_gene2419 2.157e-55 198.0 COG1704@1|root,COG1704@2|Bacteria,2GFE4@200930|Deferribacteres 200930|Deferribacteres S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA SRR34280931_k127_1031295_6 395493.BegalDRAFT_2010 3.556e-33 133.0 COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,461B8@72273|Thiotrichales 72273|Thiotrichales S RDD family - - - - - - - - - - - - RDD SRR34280931_k127_1031295_2 1449126.JQKL01000037_gene2041 2.514e-57 205.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,269FD@186813|unclassified Clostridiales 186801|Clostridia S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA SRR34280931_k127_1031295_4 1201035.KE007213_gene1553 6.178e-34 142.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,48SY2@772|Bartonellaceae 28211|Alphaproteobacteria S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase SRR34280931_k127_1031295_1 273068.TTE1794 7.361e-81 278.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia,42GEA@68295|Thermoanaerobacterales 186801|Clostridia O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 SRR34280931_k127_1031295_5 1279019.ARQK01000034_gene1114 1.001e-33 137.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1RG8H@1224|Proteobacteria,1SMYF@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,PAS_3,PAS_4,PAS_9 SRR34280931_k127_1031295_0 1238450.VIBNISOn1_1260021 5.124e-103 346.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1Y0HD@135623|Vibrionales 135623|Vibrionales F Dihydroorotate dehydrogenase - - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SRR34280931_k127_1042259_5 1463901.JOIY01000065_gene323 1.469e-06 60.0 COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GMTA@201174|Actinobacteria 201174|Actinobacteria Q Esterase, phb depolymerase family phaZ1 - - - - - - - - - - - Esterase_phd SRR34280931_k127_1042259_0 525904.Tter_1483 1.449e-190 618.0 COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria 2|Bacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 SRR34280931_k127_1042259_4 521011.Mpal_1250 2.02e-14 82.0 COG2339@1|root,arCOG02985@2157|Archaea 2157|Archaea S Membrane - - - - - - - - - - - - PrsW-protease SRR34280931_k127_1042259_3 323261.Noc_1573 1.576e-16 85.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SRR34280931_k127_1042259_2 660470.Theba_1526 1.27e-21 96.0 COG0695@1|root,COG0695@2|Bacteria,2GD7W@200918|Thermotogae 200918|Thermotogae O glutaredoxin-like protein, YruB-family - - - - - - - - - - - - Glutaredoxin SRR34280931_k127_1042259_1 1089553.Tph_c21150 3.058e-166 541.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,42F8U@68295|Thermoanaerobacterales 186801|Clostridia J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C SRR34280931_k127_1049397_1 268407.PWYN_23625 6.053e-09 67.0 COG2865@1|root,COG2865@2|Bacteria,1VS91@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - SRR34280931_k127_1049397_0 313595.P700755_002118 4.997e-79 293.0 COG0433@1|root,COG0784@1|root,COG0433@2|Bacteria,COG0784@2|Bacteria,4NU1B@976|Bacteroidetes,1I4WR@117743|Flavobacteriia 976|Bacteroidetes T TraM recognition site of TraD and TraG - - - - - - - - - - - - TraG-D_C,TrwB_AAD_bind SRR34280931_k127_1071112_2 865861.AZSU01000003_gene1940 5.242e-19 89.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae 186801|Clostridia D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE SRR34280931_k127_1071112_1 525904.Tter_1347 2.157e-62 229.0 COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iLJ478.TM0232 Glyco_tran_28_C,Glyco_transf_28 SRR34280931_k127_1071112_0 981383.AEWH01000035_gene895 6.106e-87 298.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c SRR34280931_k127_1075175_13 926561.KB900622_gene690 0.0007951 50.0 COG0849@1|root,COG0849@2|Bacteria,1UD79@1239|Firmicutes,25HUK@186801|Clostridia,3WBK1@53433|Halanaerobiales 186801|Clostridia D Cell division protein FtsA - - - - - - - - - - - - FtsA SRR34280931_k127_1075175_11 526227.Mesil_2884 8.603e-13 70.0 COG0361@1|root,COG0361@2|Bacteria,1WKD7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a SRR34280931_k127_1075175_12 344747.PM8797T_12298 7.165e-10 60.0 COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes 203682|Planctomycetes J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 SRR34280931_k127_1075175_6 879308.HMPREF9130_0693 6.309e-31 125.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,22HJ5@1570339|Peptoniphilaceae 186801|Clostridia J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 SRR34280931_k127_1075175_4 1231377.C426_0101 1.007e-33 134.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1YBMC@1357|Lactococcus 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 SRR34280931_k127_1075175_5 1396418.BATQ01000056_gene188 1.422e-33 137.0 COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,2ITP0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S4/S9 N-terminal domain - - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 SRR34280931_k127_1075175_2 1121091.AUMP01000029_gene645 1.543e-72 256.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SRR34280931_k127_1075175_7 1357399.HMPREF2087_01314 2.263e-27 114.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2YPKU@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 SRR34280931_k127_1075175_9 1047013.AQSP01000139_gene2402 3.385e-20 94.0 COG0102@1|root,COG0102@2|Bacteria,2NPCI@2323|unclassified Bacteria 2|Bacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 SRR34280931_k127_1075175_3 665956.HMPREF1032_02017 4.388e-34 135.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 186801|Clostridia J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 SRR34280931_k127_1075175_8 592015.HMPREF1705_01431 1e-20 99.0 COG0576@1|root,COG0576@2|Bacteria,3TBD9@508458|Synergistetes 508458|Synergistetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE SRR34280931_k127_1075175_0 479434.Sthe_0714 4.032e-233 737.0 COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,27Y4Z@189775|Thermomicrobia 189775|Thermomicrobia O MreB/Mbl protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 SRR34280931_k127_1075175_1 999411.HMPREF1092_01443 4.515e-95 323.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG SRR34280931_k127_1075175_10 1382306.JNIM01000001_gene1978 3.433e-20 104.0 COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi 200795|Chloroflexi S PFAM peptidase M16 domain protein - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR34280931_k127_1078203_1 926561.KB900620_gene3231 1.04e-11 74.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WBJB@53433|Halanaerobiales 186801|Clostridia L PFAM Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - GIIM,RVT_1 SRR34280931_k127_1078203_2 620914.JH621247_gene2914 4.026e-10 67.0 29ZD6@1|root,30XDZ@2|Bacteria,4PAU7@976|Bacteroidetes,1IHU4@117743|Flavobacteriia,2YM21@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_1078203_0 1144932.ATTF01000006_gene85 2.786e-16 82.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,4BQ5Z@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N SRR34280931_k127_1114505_4 521045.Kole_0355 1.094e-42 163.0 COG2804@1|root,COG2804@2|Bacteria,2GCDW@200918|Thermotogae 200918|Thermotogae NU PFAM type II secretion system protein E - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N SRR34280931_k127_1114505_2 944479.JQLX01000010_gene644 5.993e-69 249.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2M6F4@213113|Desulfurellales 28221|Deltaproteobacteria NU Type II secretion system (T2SS), protein F pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SRR34280931_k127_1114505_6 1121428.DESHY_60062___1 0.0005596 53.0 COG2165@1|root,COG2165@2|Bacteria,1W5JZ@1239|Firmicutes,256FM@186801|Clostridia 186801|Clostridia NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl SRR34280931_k127_1114505_3 243274.THEMA_01220 1.221e-48 183.0 COG0126@1|root,COG0149@1|root,COG0126@2|Bacteria,COG0149@2|Bacteria,2GBXW@200918|Thermotogae 200918|Thermotogae F belongs to the phosphoglycerate kinase family pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK,TIM SRR34280931_k127_1114505_1 237368.SCABRO_02504 1.812e-92 316.0 COG0126@1|root,COG0126@2|Bacteria,2IYIS@203682|Planctomycetes 203682|Planctomycetes F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK SRR34280931_k127_1114505_5 522772.Dacet_2702 2.02e-28 119.0 COG0537@1|root,COG0537@2|Bacteria,2GFP5@200930|Deferribacteres 200930|Deferribacteres FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT SRR34280931_k127_1114505_0 1295642.H839_13434 2.609e-110 377.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1WE5V@129337|Geobacillus 91061|Bacilli L Single-strand DNA-specific exonuclease, C terminal domain recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C SRR34280931_k127_1138209_0 626939.HMPREF9443_00952 3.427e-116 383.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4H1XS@909932|Negativicutes 909932|Negativicutes D Cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SRR34280931_k127_1138209_1 1449345.JHWC01000003_gene341 2.238e-05 55.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C SRR34280931_k127_11826_0 1185876.BN8_05885 8.117e-76 264.0 COG1004@1|root,COG1004@2|Bacteria 2|Bacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR34280931_k127_11826_1 706587.Desti_3853 3.917e-50 185.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MQ6S@213462|Syntrophobacterales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8 SRR34280931_k127_1216113_0 1068980.ARVW01000001_gene4278 4.488e-104 361.0 COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4E84C@85010|Pseudonocardiales 201174|Actinobacteria U AAA-like domain - - - - - - - - - - - - AAA_10,DUF87 SRR34280931_k127_1216113_1 886882.PPSC2_p0161 9.237e-17 88.0 2DQGV@1|root,336S4@2|Bacteria,1VJ0B@1239|Firmicutes,4HZH4@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SRR34280931_k127_1219150_0 335543.Sfum_1033 6.601e-16 84.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MQKP@213462|Syntrophobacterales 28221|Deltaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SRR34280931_k127_1219150_1 1382359.JIAL01000001_gene2496 3.272e-06 61.0 COG0457@1|root,COG0457@2|Bacteria,3Y4E6@57723|Acidobacteria,2JM2V@204432|Acidobacteriia 204432|Acidobacteriia S TPR repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_8 SRR34280931_k127_1232488_0 335541.Swol_0247 6.951e-18 96.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42JW5@68298|Syntrophomonadaceae 186801|Clostridia D Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SRR34280931_k127_1232488_1 1410617.JHXH01000003_gene575 1.862e-11 70.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae 186801|Clostridia J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SRR34280931_k127_12411_1 370438.PTH_0263 5.894e-44 164.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_bind SRR34280931_k127_12411_3 317936.Nos7107_0713 1.031e-18 94.0 2CCI4@1|root,30BPJ@2|Bacteria,1GAR7@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR34280931_k127_12411_2 1304284.L21TH_0607 8.732e-42 158.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,36I1C@31979|Clostridiaceae 186801|Clostridia K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ SRR34280931_k127_12411_0 2325.TKV_c15500 8.283e-74 258.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,42EWY@68295|Thermoanaerobacterales 186801|Clostridia J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 SRR34280931_k127_12411_4 485916.Dtox_1048 7.847e-16 88.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,260BS@186807|Peptococcaceae 186801|Clostridia M TIGRFAM stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase SRR34280931_k127_1241982_0 1209989.TepiRe1_0703 8.213e-103 342.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b SRR34280931_k127_1241982_1 511051.CSE_02410 3.847e-10 73.0 COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - CHU_C,DUF11 SRR34280931_k127_1252527_2 1121091.AUMP01000003_gene2840 8.61e-80 275.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C SRR34280931_k127_1252527_15 1392493.JIAB01000001_gene1398 1.174e-07 59.0 COG1846@1|root,COG1846@2|Bacteria,1V4IP@1239|Firmicutes,25CPP@186801|Clostridia 186801|Clostridia K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 SRR34280931_k127_1252527_13 103690.17129790 3.672e-21 108.0 COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria,1HM23@1161|Nostocales 1117|Cyanobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SRR34280931_k127_1252527_4 192952.MM_2665 2.106e-70 244.0 COG1136@1|root,arCOG00922@2157|Archaea,2XWHK@28890|Euryarchaeota,2N9GX@224756|Methanomicrobia 224756|Methanomicrobia E ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR34280931_k127_1252527_7 269797.Mbar_A2654 3.493e-43 174.0 COG0577@1|root,arCOG02315@2157|Archaea,2XYJU@28890|Euryarchaeota,2N9SS@224756|Methanomicrobia 224756|Methanomicrobia V ABC-type transport system involved in lipoprotein release permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR34280931_k127_1252527_5 745718.JADT01000019_gene1519 2.501e-50 185.0 COG0847@1|root,COG0847@2|Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T SRR34280931_k127_1252527_16 291112.PAU_02553 0.0003431 49.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endonuclease I endA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 SRR34280931_k127_1252527_12 575588.ACPN01000095_gene387 8.835e-23 100.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,3NNY1@468|Moraxellaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 SRR34280931_k127_1252527_14 936375.HMPREF1152_1816 1.808e-19 93.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WCK8@538999|Clostridiales incertae sedis 186801|Clostridia J Binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N SRR34280931_k127_1252527_3 545697.HMPREF0216_01235 9.582e-74 264.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,36DGU@31979|Clostridiaceae 186801|Clostridia M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 SRR34280931_k127_1252527_11 86416.Clopa_0737 1.082e-28 126.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,36E87@31979|Clostridiaceae 186801|Clostridia P transport protein CorA corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA SRR34280931_k127_1252527_0 309799.DICTH_1585 3.43e-140 460.0 COG0215@1|root,COG0215@2|Bacteria 2|Bacteria J cysteine-tRNA ligase activity cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e SRR34280931_k127_1252527_1 509191.AEDB02000049_gene4394 1.403e-136 448.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C SRR34280931_k127_1252527_8 1504822.CCNO01000011_gene229 7.446e-36 143.0 COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria 2|Bacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 SRR34280931_k127_1252527_9 1408311.JNJM01000014_gene3200 1.16e-29 122.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,2PSHX@265975|Oribacterium 186801|Clostridia J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p SRR34280931_k127_1252527_6 1047013.AQSP01000140_gene2513 3.28e-48 186.0 COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria 2|Bacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC SRR34280931_k127_1252527_10 497965.Cyan7822_5218 1.165e-29 123.0 COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,3KI04@43988|Cyanothece 1117|Cyanobacteria D Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY SRR34280931_k127_126255_1 1499967.BAYZ01000086_gene5149 7.556e-22 101.0 COG0438@1|root,COG0438@2|Bacteria,2NR76@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_126255_0 1313301.AUGC01000007_gene546 1.552e-112 385.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes 976|Bacteroidetes E asparagine synthase (Glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SRR34280931_k127_126255_2 797114.C475_01237 5.176e-11 72.0 COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,24182@183963|Halobacteria 183963|Halobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_1276879_7 699246.HMPREF0868_1163 2.628e-14 76.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,267UR@186813|unclassified Clostridiales 186801|Clostridia E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SRR34280931_k127_1276879_8 74547.PMT_1188 2.02e-07 61.0 COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1MNDY@1212|Prochloraceae 1117|Cyanobacteria O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 SRR34280931_k127_1276879_0 1123371.ATXH01000007_gene516 5.098e-297 936.0 COG0542@1|root,COG0542@2|Bacteria,2GGRY@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N SRR34280931_k127_1276879_5 69014.TK2143 3.79e-51 188.0 COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,243FM@183968|Thermococci 183968|Thermococci L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SRR34280931_k127_1276879_9 1122147.AUEH01000004_gene1014 0.0003797 46.0 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 SRR34280931_k127_1276879_6 518766.Rmar_0775 5.325e-26 111.0 COG0745@1|root,COG0745@2|Bacteria 518766.Rmar_0775|- T phosphorelay signal transduction system - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - - SRR34280931_k127_1276879_3 485913.Krac_9139 4.678e-61 221.0 COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT SRR34280931_k127_1276879_10 44060.JODL01000017_gene4205 0.0006535 49.0 COG1051@1|root,COG1051@2|Bacteria,2IJBH@201174|Actinobacteria 201174|Actinobacteria F NUDIX domain - - - - - - - - - - - - NUDIX SRR34280931_k127_1276879_4 525904.Tter_0501 5.288e-55 205.0 COG1475@1|root,COG1475@2|Bacteria,2NP7S@2323|unclassified Bacteria 2|Bacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SRR34280931_k127_1276879_1 351627.Csac_1001 2.058e-128 426.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales 186801|Clostridia KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS16615 ACT_4,HD_4,RelA_SpoT,TGS SRR34280931_k127_1276879_2 2340.JV46_25840 2.091e-112 378.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom SRR34280931_k127_1307987_2 1415754.JQMK01000002_gene2765 8.317e-23 106.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,46525@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease VP2476 - - - - - - - - - - - AI-2E_transport SRR34280931_k127_1307987_1 926556.Echvi_0752 3.454e-110 369.0 COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia 976|Bacteroidetes G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_transf_4,Glyco_transf_5,Glycos_transf_1 SRR34280931_k127_1307987_0 352165.HMPREF7215_1007 1.53e-143 463.0 COG1449@1|root,COG1449@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 57 family amyA - 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH57 - Glyco_hydro_57 SRR34280931_k127_1310344_1 305700.B447_20900 7.323e-50 183.0 COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2VQ8E@28216|Betaproteobacteria,2KYRU@206389|Rhodocyclales 206389|Rhodocyclales S Flavodoxin-like fold - - 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - Flavodoxin_2 SRR34280931_k127_1310344_0 187303.BN69_1880 8.35e-61 219.0 COG1940@1|root,COG1940@2|Bacteria 2|Bacteria GK ROK family nanK - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK SRR34280931_k127_1310344_2 1306947.ARQD01000005_gene49 4.215e-09 63.0 COG0166@1|root,COG0166@2|Bacteria,2NP2H@2323|unclassified Bacteria 2|Bacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iLJ478.TM1385 PGI SRR34280931_k127_13294_1 697282.Mettu_1987 2.647e-35 155.0 COG5306@1|root,COG5306@2|Bacteria 2|Bacteria - - exbB2 - 3.4.14.5 ko:K01278,ko:K03561,ko:K12287 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko02044,ko04090,ko04147 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB SRR34280931_k127_13294_2 1120934.KB894417_gene2421 0.000552 53.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - Laminin_G_3,UnbV_ASPIC,VCBS SRR34280931_k127_13294_0 697282.Mettu_1987 1.436e-52 209.0 COG5306@1|root,COG5306@2|Bacteria 2|Bacteria - - exbB2 - 3.4.14.5 ko:K01278,ko:K03561,ko:K12287 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko02044,ko04090,ko04147 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB SRR34280931_k127_1357877_3 871968.DESME_13845 2.937e-81 281.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae 186801|Clostridia V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR34280931_k127_1357877_14 946077.W5A_04978 3.713e-21 98.0 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - PRA-PH SRR34280931_k127_1357877_9 518766.Rmar_0714 5.742e-58 216.0 28IX1@1|root,2Z8V3@2|Bacteria,4NHFP@976|Bacteroidetes,1FJ3K@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Protein of unknown function (DUF2914) - - - - - - - - - - - - DUF2914 SRR34280931_k127_1357877_2 1122179.KB890435_gene893 6.543e-98 338.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C SRR34280931_k127_1357877_8 717785.HYPMC_1306 5.827e-62 215.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria 28211|Alphaproteobacteria O methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR SRR34280931_k127_1357877_5 861299.J421_0778 2.043e-65 228.0 COG0225@1|root,COG0225@2|Bacteria,1ZUAQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR SRR34280931_k127_1357877_1 1203605.HMPREF1531_01505 3.364e-110 379.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2HPPV@201174|Actinobacteria,4DVCD@85009|Propionibacteriales 201174|Actinobacteria O Cytochrome C biogenesis protein - - - - - - - - - - - - - SRR34280931_k127_1357877_17 1151117.AJLF01000001_gene1582 1.038e-15 78.0 COG1476@1|root,arCOG01864@2157|Archaea,2XZS8@28890|Euryarchaeota,244GH@183968|Thermococci 183968|Thermococci K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 SRR34280931_k127_1357877_13 1161401.ASJA01000021_gene651 9.563e-24 104.0 COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2UDEK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Membrane protein of - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 SRR34280931_k127_1357877_12 501479.ACNW01000051_gene3465 2.252e-32 134.0 COG0586@1|root,COG0586@2|Bacteria,1RFHI@1224|Proteobacteria,2U80A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SRR34280931_k127_1357877_10 1105367.CG50_08490 5.089e-55 200.0 COG1216@1|root,COG1216@2|Bacteria,1RBC1@1224|Proteobacteria,2U6GY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_1357877_11 932213.SPM24T3_01918 3.662e-53 195.0 COG1216@1|root,COG1216@2|Bacteria,1RBC1@1224|Proteobacteria 1224|Proteobacteria S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_1357877_4 1159870.KB907784_gene2947 7.166e-69 241.0 COG1216@1|root,COG1216@2|Bacteria,1QZYZ@1224|Proteobacteria 1224|Proteobacteria S Glycosyl transferase family group 2 - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_1357877_18 1121946.AUAX01000005_gene5145 1.41e-12 78.0 2C454@1|root,3440S@2|Bacteria,2GSV4@201174|Actinobacteria,4DG4S@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SRR34280931_k127_1357877_16 469596.HMPREF9488_02537 1.741e-19 93.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,3VREG@526524|Erysipelotrichia 526524|Erysipelotrichia M Prokaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_prokar SRR34280931_k127_1357877_6 266117.Rxyl_1327 2.345e-64 223.0 COG2514@1|root,COG2514@2|Bacteria,2HNS6@201174|Actinobacteria,4CPZV@84995|Rubrobacteria 84995|Rubrobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase SRR34280931_k127_1357877_7 858215.Thexy_0673 2.316e-62 235.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,42F7H@68295|Thermoanaerobacterales 186801|Clostridia S pfam abc - - - ko:K06158,ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn SRR34280931_k127_1357877_0 1122169.AREN01000004_gene515 2.256e-144 475.0 COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,1S1GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L helicase pif1 - - - - - - - - - - - HTH_40,PIF1 SRR34280931_k127_1366123_4 1122619.KB892306_gene2366 1.039e-05 56.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,3T295@506|Alcaligenaceae 28216|Betaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport SRR34280931_k127_1366123_1 643648.Slip_0641 2.146e-64 233.0 COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia 186801|Clostridia M Capsule synthesis protein capA - - ko:K07282 - - - - ko00000 - - - PGA_cap,Peptidase_M15 SRR34280931_k127_1366123_3 1499680.CCFE01000011_gene590 8.036e-11 68.0 COG1051@1|root,COG1051@2|Bacteria,1V6X2@1239|Firmicutes,4HJ54@91061|Bacilli,1ZQ2R@1386|Bacillus 91061|Bacilli F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX SRR34280931_k127_1366123_0 635013.TherJR_2771 1.89e-270 856.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,260C9@186807|Peptococcaceae 186801|Clostridia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW SRR34280931_k127_1366123_2 929703.KE386491_gene1828 5.715e-49 198.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - - - - - - - - - - Wzy_C SRR34280931_k127_1377286_4 1220589.CD32_22890 1.199e-18 93.0 2CCGS@1|root,32UCE@2|Bacteria,1V9YN@1239|Firmicutes,4HKU7@91061|Bacilli,3IZHR@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - SRR34280931_k127_1377286_2 1094715.CM001373_gene2605 2.474e-30 121.0 COG4430@1|root,COG4430@2|Bacteria,1RGC9@1224|Proteobacteria,1SE5C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1905,OmdA SRR34280931_k127_1377286_7 1347087.CBYO010000014_gene2137 0.0001422 45.0 2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SRR34280931_k127_1377286_5 123214.PERMA_1406 7.808e-09 61.0 COG1872@1|root,COG1872@2|Bacteria,2G5B9@200783|Aquificae 200783|Aquificae S Belongs to the UPF0235 family - - - ko:K09131 - - - - ko00000 - - - DUF167 SRR34280931_k127_1377286_6 1121346.KB899817_gene3188 9.485e-07 55.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,26R9J@186822|Paenibacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE SRR34280931_k127_1377286_0 868864.Dester_0062 3.815e-53 198.0 COG0223@1|root,COG0223@2|Bacteria,2G3PD@200783|Aquificae 200783|Aquificae J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N SRR34280931_k127_1377286_3 1162668.LFE_2450 1.041e-23 107.0 COG0242@1|root,COG0242@2|Bacteria,3J146@40117|Nitrospirae 40117|Nitrospirae J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase SRR34280931_k127_1377286_1 536227.CcarbDRAFT_2587 4.55e-37 154.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,36DH7@31979|Clostridiaceae 186801|Clostridia L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII SRR34280931_k127_1379155_2 351160.RCIX17 4.751e-07 54.0 COG2155@1|root,arCOG03620@2157|Archaea,2Y0RG@28890|Euryarchaeota,2NA3Z@224756|Methanomicrobia 224756|Methanomicrobia S Domain of unknown function (DUF378) - - - ko:K09779 - - - - ko00000 - - - DUF378 SRR34280931_k127_1379155_1 292.DM42_2718 6.771e-15 77.0 2EGBE@1|root,33A39@2|Bacteria,1N3MX@1224|Proteobacteria,2W4FB@28216|Betaproteobacteria,1KAFZ@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR34280931_k127_1379155_0 1121428.DESHY_40188___1 3.794e-177 570.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,260A4@186807|Peptococcaceae 186801|Clostridia O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SRR34280931_k127_139493_1 1304284.L21TH_1732 1.15e-93 321.0 COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,36DQZ@31979|Clostridiaceae 186801|Clostridia J metallo-beta-lactamase - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL SRR34280931_k127_139493_3 768679.TTX_0564 6.538e-46 172.0 COG0105@1|root,arCOG04313@2157|Archaea,2XQEV@28889|Crenarchaeota 28889|Crenarchaeota F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SRR34280931_k127_139493_2 644966.Tmar_2274 2.298e-69 243.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WCH7@538999|Clostridiales incertae sedis 186801|Clostridia E Metallopeptidase family M24 map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SRR34280931_k127_139493_6 759914.BP951000_2312 1.058e-15 85.0 COG0563@1|root,COG0563@2|Bacteria,2J6MV@203691|Spirochaetes 203691|Spirochaetes F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid SRR34280931_k127_139493_0 309801.trd_0965 5.723e-105 355.0 COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia 189775|Thermomicrobia U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SRR34280931_k127_139493_7 1382306.JNIM01000001_gene3530 3.384e-13 76.0 COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi 200795|Chloroflexi J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A SRR34280931_k127_139493_4 1117644.MCANPG14_03310 1.183e-31 131.0 COG0098@1|root,COG0098@2|Bacteria,3WTIC@544448|Tenericutes 544448|Tenericutes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C SRR34280931_k127_139493_5 1129368.SMIPMB4A_v3c6820 2.678e-30 122.0 COG0256@1|root,COG0256@2|Bacteria,3WTJJ@544448|Tenericutes 544448|Tenericutes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p SRR34280931_k127_1408701_0 706587.Desti_3853 7.955e-92 317.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MQ6S@213462|Syntrophobacterales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8 SRR34280931_k127_1408701_1 1047013.AQSP01000118_gene1252 3.548e-87 296.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - - SRR34280931_k127_1411193_0 1089548.KI783301_gene3209 1.705e-120 400.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3WDW8@539002|Bacillales incertae sedis 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SRR34280931_k127_1411193_2 1128421.JAGA01000003_gene3142 4.401e-56 206.0 COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria 2|Bacteria LU DNA recombination-mediator protein A dprA - 5.99.1.2 ko:K03168,ko:K04096 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_processg_A SRR34280931_k127_1411193_1 458233.MCCL_0834 3.085e-83 285.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,4GXFS@90964|Staphylococcaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom SRR34280931_k127_1415441_0 555079.Toce_0657 7.318e-117 392.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales 186801|Clostridia J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey SRR34280931_k127_1415441_1 1353531.AZNX01000007_gene245 5.204e-77 269.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,4B9XG@82115|Rhizobiaceae 28211|Alphaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 SRR34280931_k127_1415441_3 314345.SPV1_02252 2.234e-62 225.0 COG4286@1|root,COG4286@2|Bacteria,1MVTY@1224|Proteobacteria 1224|Proteobacteria S conserved protein related to MYG1 family - - - - - - - - - - - - UPF0160 SRR34280931_k127_1415441_2 429009.Adeg_0202 1.382e-67 238.0 COG3387@1|root,COG3387@2|Bacteria,1TSFD@1239|Firmicutes,24EW4@186801|Clostridia,42F5M@68295|Thermoanaerobacterales 186801|Clostridia G glycoside hydrolase 15-related - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glucodextran_N,Glyco_hydro_15 SRR34280931_k127_1427257_2 102232.GLO73106DRAFT_00006970 9.164e-30 121.0 COG1186@1|root,COG1186@2|Bacteria,1G1QH@1117|Cyanobacteria 1117|Cyanobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR34280931_k127_1427257_0 2325.TKV_c18060 6.496e-75 258.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales 186801|Clostridia D TIGRFAM Cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran SRR34280931_k127_1427257_3 931626.Awo_c25370 2.514e-23 111.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,25VJS@186806|Eubacteriaceae 186801|Clostridia D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX SRR34280931_k127_1427257_1 1506583.JQJY01000003_gene3271 4.475e-61 216.0 COG0330@1|root,COG0330@2|Bacteria,4NHU9@976|Bacteroidetes,1HXK0@117743|Flavobacteriia,2NUJI@237|Flavobacterium 976|Bacteroidetes O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 SRR34280931_k127_143756_3 91464.S7335_2400 1.699e-47 177.0 COG1186@1|root,COG1186@2|Bacteria,1G1QH@1117|Cyanobacteria,1GYIK@1129|Synechococcus 1117|Cyanobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR34280931_k127_143756_2 1459636.NTE_01132 6.587e-51 184.0 COG3865@1|root,arCOG09469@2157|Archaea 2157|Archaea S PFAM 3-demethylubiquinone-9 - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt SRR34280931_k127_143756_1 1123371.ATXH01000006_gene873 3.173e-149 485.0 COG0154@1|root,COG0154@2|Bacteria,2GHH3@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase SRR34280931_k127_143756_5 1173029.JH980292_gene143 2.317e-06 53.0 COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria,1HC33@1150|Oscillatoriales 1117|Cyanobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln SRR34280931_k127_143756_0 688269.Theth_0908 6.326e-188 609.0 COG0272@1|root,COG0272@2|Bacteria,2GCF6@200918|Thermotogae 200918|Thermotogae L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 SRR34280931_k127_143756_4 717606.PaecuDRAFT_2080 1.045e-08 59.0 COG2819@1|root,COG3291@1|root,COG4733@1|root,COG2819@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.20 ko:K01187,ko:K03466,ko:K07017 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000,ko03036 3.A.12 GH31 - Alpha-amylase,CBM_25,DUF1080,Esterase,GH97_C,GH97_N,Glyco_hydro_97,PKD,fn3 SRR34280931_k127_1450905_0 698758.AXY_03630 2.683e-64 232.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SRR34280931_k127_1450905_1 1121904.ARBP01000019_gene2815 1.243e-24 113.0 COG0615@1|root,COG0615@2|Bacteria,4NGSD@976|Bacteroidetes 976|Bacteroidetes IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like,GHMP_kinases_C SRR34280931_k127_1451952_2 1473546.CH76_09370 9.351e-20 97.0 COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,3IXDS@400634|Lysinibacillus 91061|Bacilli J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SRR34280931_k127_1451952_0 574087.Acear_0203 4.87e-84 299.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia 186801|Clostridia C TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit glpC - 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - CCG,Fer4_8 SRR34280931_k127_1451952_1 1267533.KB906733_gene2984 1.037e-80 278.0 COG0191@1|root,COG0191@2|Bacteria 2|Bacteria G fructose-bisphosphate aldolase activity agaY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase SRR34280931_k127_156835_0 523791.Kkor_1317 2.798e-59 219.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1XK3U@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N SRR34280931_k127_156835_4 314230.DSM3645_20532 3.05e-15 77.0 COG1278@1|root,COG1278@2|Bacteria,2J13Y@203682|Planctomycetes 203682|Planctomycetes K COG1278 Cold shock - - - - - - - - - - - - CSD SRR34280931_k127_156835_1 751944.HALDL1_12405 9.649e-37 151.0 arCOG04564@1|root,arCOG04564@2157|Archaea,2XTME@28890|Euryarchaeota,23SGS@183963|Halobacteria 183963|Halobacteria S PFAM DoxX family protein - - - - - - - - - - - - DoxX SRR34280931_k127_156835_2 1291743.LOSG293_340010 2.742e-23 102.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB SRR34280931_k127_160152_1 260799.BAS3966 1.01e-25 118.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZGQD@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - CW_binding_2,LTD,Lactamase_B SRR34280931_k127_160152_0 552811.Dehly_0410 1.984e-42 163.0 COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi,34D0I@301297|Dehalococcoidia 301297|Dehalococcoidia C Iron/manganese superoxide dismutases, C-terminal domain sod - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C SRR34280931_k127_165528_1 290315.Clim_1170 2.293e-35 140.0 COG0566@1|root,COG0566@2|Bacteria,1FDZH@1090|Chlorobi 1090|Chlorobi H PFAM tRNA rRNA methyltransferase (SpoU) - - - - - - - - - - - - SpoU_methylase SRR34280931_k127_165528_3 1254432.SCE1572_49425 6.902e-07 57.0 COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions 1224|Proteobacteria S DoxX family - - - ko:K15977 - - - - ko00000 - - - DoxX SRR34280931_k127_165528_0 765869.BDW_02740 1.802e-148 498.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2MSP6@213481|Bdellovibrionales,2WJ3W@28221|Deltaproteobacteria 213481|Bdellovibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SRR34280931_k127_165528_2 1249997.JHZW01000003_gene2628 1.45e-10 64.0 COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1I3XP@117743|Flavobacteriia,2PHP8@252356|Maribacter 976|Bacteroidetes S Threonylcarbamoyl adenosine biosynthesis protein TsaE yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE SRR34280931_k127_209084_8 911045.PSE_3445 3.234e-10 61.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SRR34280931_k127_209084_6 656024.FsymDg_4426 5.397e-22 98.0 COG1162@1|root,COG1162@2|Bacteria,2GU32@201174|Actinobacteria,4EWKA@85013|Frankiales 201174|Actinobacteria S RNHCP domain - - - - - - - - - - - - RNHCP SRR34280931_k127_209084_1 521011.Mpal_2170 3.538e-88 299.0 COG1194@1|root,arCOG00462@2157|Archaea,2XSU9@28890|Euryarchaeota,2NBC3@224756|Methanomicrobia 224756|Methanomicrobia L PFAM HhH-GPD family protein - - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD SRR34280931_k127_209084_7 655811.HMPREF0078_1106 1.546e-14 79.0 COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,22HTU@1570339|Peptoniphilaceae 186801|Clostridia L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 SRR34280931_k127_209084_0 596324.TREVI0001_1665 2.995e-97 336.0 COG0617@1|root,COG0617@2|Bacteria,2J5ZC@203691|Spirochaetes 203691|Spirochaetes H PolyA polymerase papS - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 SRR34280931_k127_209084_2 1203606.HMPREF1526_00881 1.619e-80 275.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,36E73@31979|Clostridiaceae 186801|Clostridia L exodeoxyribonuclease III xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos SRR34280931_k127_209084_4 56780.SYN_00952 2.683e-47 182.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2MQX6@213462|Syntrophobacterales 28221|Deltaproteobacteria D Tyrosine recombinase XerD xerD - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR34280931_k127_209084_5 2325.TKV_c13050 7.397e-23 100.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales 186801|Clostridia J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 SRR34280931_k127_209084_3 1047013.AQSP01000107_gene2079 1.468e-54 196.0 COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria 2|Bacteria S NYN domain - - - - - - - - - - - - NYN SRR34280931_k127_209387_0 477974.Daud_1466 4.512e-118 389.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,260KS@186807|Peptococcaceae 186801|Clostridia D TIGRFAM Cell shape determining protein MreB Mrl mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SRR34280931_k127_209387_1 1150469.RSPPHO_00045 6.502e-91 314.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2JQ5E@204441|Rhodospirillales 204441|Rhodospirillales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b SRR34280931_k127_214281_2 311424.DhcVS_380 5.161e-42 164.0 COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,34CSJ@301297|Dehalococcoidia 301297|Dehalococcoidia J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL SRR34280931_k127_214281_1 479434.Sthe_1249 3.688e-73 268.0 COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia 189775|Thermomicrobia E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SRR34280931_k127_214281_4 1382356.JQMP01000003_gene2508 0.0002123 47.0 COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia 189775|Thermomicrobia U Preprotein translocase SecG subunit - - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG SRR34280931_k127_214281_3 1157637.KB892128_gene3277 4.665e-17 87.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria 201174|Actinobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 SRR34280931_k127_214281_0 1121428.DESHY_160190___1 5.246e-184 590.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2611G@186807|Peptococcaceae 186801|Clostridia O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SRR34280931_k127_218301_0 720554.Clocl_1852 4.898e-98 334.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae 186801|Clostridia S Flavoprotein family - - - ko:K07007 - - - - ko00000 - - - HI0933_like SRR34280931_k127_218301_1 493475.GARC_2376 8.186e-59 215.0 COG3187@1|root,COG3187@2|Bacteria 2|Bacteria O response to heat - - - ko:K03668,ko:K03929 - - - - ko00000,ko01000 - CE10 - META SRR34280931_k127_248230_4 262724.TT_C1013 0.0001162 50.0 COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus NU TIGRFAM type IV pilus assembly protein PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 SRR34280931_k127_248230_0 246194.CHY_0630 1.218e-113 388.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales 186801|Clostridia NU PFAM Type II secretion system protein E pilB - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N SRR34280931_k127_248230_3 395494.Galf_1976 2.581e-12 72.0 COG0784@1|root,COG0784@2|Bacteria,1QVBY@1224|Proteobacteria,2VRK5@28216|Betaproteobacteria 28216|Betaproteobacteria T response regulator - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg SRR34280931_k127_248230_1 469381.Dpep_2276 1.752e-95 323.0 COG2805@1|root,COG2805@2|Bacteria,3T9Z7@508458|Synergistetes 508458|Synergistetes NU PFAM type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SRR34280931_k127_248230_2 574087.Acear_1772 1.972e-67 244.0 COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WAFC@53433|Halanaerobiales 186801|Clostridia U PFAM Bacterial type II secretion system protein F domain - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SRR34280931_k127_249500_17 204669.Acid345_1837 3.192e-17 87.0 2ET93@1|root,33KT4@2|Bacteria,3Y5XM@57723|Acidobacteria,2JK3T@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - SRR34280931_k127_249500_18 374847.Kcr_0268 2.151e-15 83.0 COG1502@1|root,arCOG02041@2157|Archaea 2157|Archaea I Phospholipase D Transphosphatidylase - - - ko:K06131,ko:K06132,ko:K06915 ko00564,ko01100,map00564,map01100 - R07390,R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 SRR34280931_k127_249500_7 1382356.JQMP01000004_gene130 3.181e-61 217.0 COG0586@1|root,COG0586@2|Bacteria,2GBDA@200795|Chloroflexi,27YWX@189775|Thermomicrobia 189775|Thermomicrobia S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc SRR34280931_k127_249500_19 931276.Cspa_c37850 3.032e-09 63.0 2ED1S@1|root,336YP@2|Bacteria,1VJRI@1239|Firmicutes,24UCF@186801|Clostridia,36T2P@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - SRR34280931_k127_249500_20 224719.Abm4_1599 2.768e-08 65.0 COG0392@1|root,arCOG00899@2157|Archaea,2XTI1@28890|Euryarchaeota,23NKG@183925|Methanobacteria 183925|Methanobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SRR34280931_k127_249500_9 1183438.GKIL_3645 1.681e-47 173.0 COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria 1117|Cyanobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL SRR34280931_k127_249500_10 521045.Kole_2102 2.421e-45 171.0 COG0130@1|root,COG0130@2|Bacteria,2GCEK@200918|Thermotogae 200918|Thermotogae J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - PUA,TruB_C_2,TruB_N SRR34280931_k127_249500_15 1449346.JQMO01000002_gene1405 1.136e-23 111.0 COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria,2M0UG@2063|Kitasatospora 201174|Actinobacteria K Sigma-70 region 2 - - - - - - - - - - - - CAP,Sigma70_r2 SRR34280931_k127_249500_2 1379698.RBG1_1C00001G1686 1.957e-249 782.0 COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria 2|Bacteria T Elongation factor G C-terminus typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 SRR34280931_k127_249500_14 321332.CYB_2425 9.886e-35 141.0 COG0283@1|root,COG0414@1|root,COG0283@2|Bacteria,COG0414@2|Bacteria,1G1BX@1117|Cyanobacteria,1GZ7F@1129|Synechococcus 1117|Cyanobacteria F Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC/cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 ko:K13799 ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110 M00052,M00119 R00158,R00512,R01665,R02473 RC00002,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin,Pantoate_ligase SRR34280931_k127_249500_16 1122173.AXVL01000021_gene2212 3.512e-18 94.0 COG0130@1|root,COG0130@2|Bacteria,378NK@32066|Fusobacteria 32066|Fusobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N SRR34280931_k127_249500_5 862908.BMS_0446 3.411e-97 332.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2MT5M@213481|Bdellovibrionales,2WJE1@28221|Deltaproteobacteria 213481|Bdellovibrionales J PFAM tRNA synthetase, class II (G, H, P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His SRR34280931_k127_249500_13 96561.Dole_1953 1.832e-36 145.0 COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MI86@213118|Desulfobacterales 28221|Deltaproteobacteria L DEAD DEAH box helicase yprA - - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C,RNase_H_2 SRR34280931_k127_249500_8 667014.Thein_0649 1.59e-54 200.0 COG1968@1|root,COG1968@2|Bacteria,2GHT2@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria V Bacitracin resistance protein BacA uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA SRR34280931_k127_249500_12 1499967.BAYZ01000076_gene830 3.425e-38 153.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - - - - - - - - - - Thioredoxin_4 SRR34280931_k127_249500_3 925409.KI911562_gene466 2.988e-128 446.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C SRR34280931_k127_249500_4 1118057.CAGX01000021_gene1674 6.829e-108 363.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,22GJT@1570339|Peptoniphilaceae 186801|Clostridia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR34280931_k127_249500_6 313628.LNTAR_02252 1.023e-84 303.0 COG0358@1|root,COG0358@2|Bacteria 2|Bacteria L DNA primase activity dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 SRR34280931_k127_249500_0 521460.Athe_0805 0.0 1160.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,42FED@68295|Thermoanaerobacterales 186801|Clostridia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 SRR34280931_k127_249500_1 645991.Sgly_0384 0.0 1109.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25ZXZ@186807|Peptococcaceae 186801|Clostridia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 SRR34280931_k127_249500_11 1265505.ATUG01000002_gene2612 2.697e-39 153.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2MIUI@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - Methyltrn_RNA_4,tRNA_m1G_MT SRR34280931_k127_262119_0 671143.DAMO_2856 2.943e-245 793.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon SRR34280931_k127_262119_2 401526.TcarDRAFT_1560 9.197e-05 52.0 COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,4H9AT@909932|Negativicutes 909932|Negativicutes U Pfam:N_methyl_2 - - - - - - - - - - - - N_methyl,T2SSG SRR34280931_k127_262119_1 546271.Selsp_0889 4.237e-35 140.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes 909932|Negativicutes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SRR34280931_k127_264926_1 696125.BARCL_0671 5.092e-30 127.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,48TGY@772|Bartonellaceae 28211|Alphaproteobacteria J arginyl-tRNA aminoacylation argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR34280931_k127_264926_2 1117318.PRUB_01929 2.682e-29 125.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,2PZI7@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin SRR34280931_k127_264926_0 5786.XP_003284301.1 9.682e-67 234.0 COG0717@1|root,2RDXQ@2759|Eukaryota,3XCUB@554915|Amoebozoa 554915|Amoebozoa F dUTPase - - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase SRR34280931_k127_264926_3 1297570.MESS4_510064 2.32e-17 87.0 COG1351@1|root,COG1351@2|Bacteria 2|Bacteria F thymidylate synthase (FAD) activity - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 SRR34280931_k127_265103_5 404589.Anae109_2288 1.489e-29 125.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_1434 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR34280931_k127_265103_0 996637.SGM_4119 6.603e-93 315.0 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt SRR34280931_k127_265103_3 935261.JAGL01000008_gene2382 6.868e-37 146.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,43JSB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 SRR34280931_k127_265103_6 1283299.AUKG01000002_gene4783 4.72e-23 104.0 COG0537@1|root,COG0537@2|Bacteria,2HQY9@201174|Actinobacteria,4CSQS@84995|Rubrobacteria 84995|Rubrobacteria FG HIT domain - - - - - - - - - - - - - SRR34280931_k127_265103_1 909613.UO65_0496 3.048e-59 215.0 COG2131@1|root,COG2131@2|Bacteria,2IEBI@201174|Actinobacteria 201174|Actinobacteria F MafB19-like deaminase - - - - - - - - - - - - dCMP_cyt_deam_1 SRR34280931_k127_265103_2 909613.UO65_0497 2.237e-45 171.0 COG0615@1|root,COG0615@2|Bacteria,2IADS@201174|Actinobacteria 201174|Actinobacteria IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like SRR34280931_k127_265103_4 1379270.AUXF01000004_gene3352 8.868e-34 134.0 2ECN0@1|root,336JY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - VPEP SRR34280931_k127_27366_10 1382304.JNIL01000001_gene1677 7.885e-10 71.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4H9TH@91061|Bacilli,279DM@186823|Alicyclobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - SBP_bac_8 SRR34280931_k127_27366_8 558169.AGAV01000005_gene1989 1.745e-14 81.0 COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HIUG@91061|Bacilli 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 SRR34280931_k127_27366_0 941824.TCEL_02022 8.927e-261 827.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae 186801|Clostridia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SRR34280931_k127_27366_6 525904.Tter_0072 5.013e-26 116.0 COG2220@1|root,COG2220@2|Bacteria,2NR9T@2323|unclassified Bacteria 2|Bacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 SRR34280931_k127_27366_3 929506.CbC4_0536 5.04e-45 181.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,36DPA@31979|Clostridiaceae 186801|Clostridia J Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - LYTB,S1 SRR34280931_k127_27366_5 1410653.JHVC01000012_gene2317 3e-34 138.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,36G0N@31979|Clostridiaceae 186801|Clostridia J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro SRR34280931_k127_27366_4 1121468.AUBR01000050_gene2015 2.485e-37 149.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales 186801|Clostridia U PFAM Peptidase S24 S26A S26B, conserved region lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 SRR34280931_k127_27366_7 1232430.CAVG010000080_gene730 1.906e-24 117.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,4GXBX@90964|Staphylococcaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His SRR34280931_k127_27366_9 515635.Dtur_1328 8.787e-13 74.0 COG0319@1|root,COG0319@2|Bacteria 2|Bacteria C Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 - - - UPF0054 SRR34280931_k127_27366_2 1382306.JNIM01000001_gene41 1.117e-48 190.0 COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi 200795|Chloroflexi D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SRR34280931_k127_27366_1 349161.Dred_0684 4.335e-115 383.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae 186801|Clostridia D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin SRR34280931_k127_281559_0 760142.Hipma_0827 1.108e-79 286.0 COG1961@1|root,COG1961@2|Bacteria 2|Bacteria L recombinase activity - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom SRR34280931_k127_281559_2 502025.Hoch_3495 8.581e-41 158.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2Z0PW@29|Myxococcales 28221|Deltaproteobacteria L endonuclease III - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD SRR34280931_k127_281559_1 497964.CfE428DRAFT_6003 2.556e-67 246.0 COG1408@1|root,COG1408@2|Bacteria,46T0Y@74201|Verrucomicrobia 74201|Verrucomicrobia S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos SRR34280931_k127_281559_3 3218.PP1S55_203V6.1 5.895e-06 55.0 COG4243@1|root,2QRER@2759|Eukaryota,37R21@33090|Viridiplantae,3GA2R@35493|Streptophyta 35493|Streptophyta S thiol-disulfide oxidoreductase - GO:0003674,GO:0003824,GO:0003955,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010207,GO:0015979,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0019684,GO:0022607,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065003,GO:0071840 - - - - - - - - - - VKOR SRR34280931_k127_283181_2 485915.Dret_0315 3.579e-11 66.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2M8FJ@213115|Desulfovibrionales 28221|Deltaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind SRR34280931_k127_283181_3 768704.Desmer_1004 1.45e-06 60.0 COG4972@1|root,COG4972@2|Bacteria,1VGBK@1239|Firmicutes,24TXQ@186801|Clostridia,262ZS@186807|Peptococcaceae 186801|Clostridia NU PFAM Competence protein A - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilN SRR34280931_k127_283181_0 1423755.BAML01000005_gene469 1.039e-44 172.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SRR34280931_k127_283181_1 148814.JI66_02220 6.626e-21 99.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 SRR34280931_k127_287270_1 509191.AEDB02000086_gene2766 2.972e-75 263.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WG87@541000|Ruminococcaceae 186801|Clostridia E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SRR34280931_k127_287270_2 768706.Desor_5629 4.785e-13 76.0 COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,262K8@186807|Peptococcaceae 186801|Clostridia D Protein of unknown function (DUF4446) - - - - - - - - - - - - DUF4446 SRR34280931_k127_287270_0 1303518.CCALI_01342 1.049e-106 363.0 COG0532@1|root,COG0532@2|Bacteria 2|Bacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N SRR34280931_k127_287270_3 1379281.AVAG01000004_gene151 4.926e-07 57.0 COG0858@1|root,COG0858@2|Bacteria 2|Bacteria J rRNA processing rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA SRR34280931_k127_29113_0 443255.SCLAV_3084 3.352e-109 367.0 COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria 201174|Actinobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12,6.1.1.23 ko:K01876,ko:K09759 ko00970,map00970 M00359,M00360 R03647,R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - tRNA-synt_2,tRNA_anti-codon SRR34280931_k127_29113_1 596323.HMPREF0554_1642 3.588e-88 301.0 COG0180@1|root,COG0180@2|Bacteria,37854@32066|Fusobacteria 32066|Fusobacteria J Psort location Cytoplasmic, score trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b SRR34280931_k127_29113_2 1123368.AUIS01000006_gene574 2.122e-24 119.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg SRR34280931_k127_29113_3 1173026.Glo7428_0554 3.96e-15 81.0 COG2940@1|root,COG2940@2|Bacteria 2|Bacteria K SET domain - - - ko:K07117 - - - - ko00000 - - - SET SRR34280931_k127_29113_4 1541065.JRFE01000014_gene1306 1.827e-11 72.0 2CCI4@1|root,30BPJ@2|Bacteria,1GAR7@1117|Cyanobacteria,3VMXW@52604|Pleurocapsales 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR34280931_k127_309270_0 555079.Toce_0164 8.422e-93 314.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_bind SRR34280931_k127_322702_4 1047013.AQSP01000118_gene1252 1.303e-19 92.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - - SRR34280931_k127_322702_3 596154.Alide2_4721 3.367e-29 119.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 SRR34280931_k127_322702_6 1459636.NTE_03024 1.415e-10 69.0 COG1430@1|root,arCOG03116@2157|Archaea 2157|Archaea S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 SRR34280931_k127_322702_0 443906.CMM_2429 1.343e-317 994.0 COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4FKB4@85023|Microbacteriaceae 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN SRR34280931_k127_322702_1 585531.HMPREF0063_12135 2.279e-150 482.0 COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4DQK2@85009|Propionibacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm SRR34280931_k127_322702_2 1173027.Mic7113_5594 1.458e-95 325.0 COG0057@1|root,COG0057@2|Bacteria,1G1CS@1117|Cyanobacteria,1H7J0@1150|Oscillatoriales 1117|Cyanobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SRR34280931_k127_322702_5 1304866.K413DRAFT_0461 5.034e-17 84.0 COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia,36KRV@31979|Clostridiaceae 186801|Clostridia S phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - DUF429,MazG-like SRR34280931_k127_32611_1 509635.N824_17230 8.536e-66 226.0 COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1IS68@117747|Sphingobacteriia 976|Bacteroidetes S Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt,Glyoxalase SRR34280931_k127_32611_2 1220534.B655_2000 2.577e-26 111.0 COG5646@1|root,arCOG09457@2157|Archaea,2Y1ED@28890|Euryarchaeota 28890|Euryarchaeota S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 SRR34280931_k127_32611_0 546270.GEMHA0001_0540 6.039e-71 254.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3WE4C@539002|Bacillales incertae sedis 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 SRR34280931_k127_32611_3 379066.GAU_0515 7.056e-24 115.0 COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria,1ZUDA@142182|Gemmatimonadetes 142182|Gemmatimonadetes N Bacterial Ig-like domain 2 - - - - - - - - - - - - Big_2 SRR34280931_k127_344388_2 243164.DET0404 2.031e-52 194.0 COG0030@1|root,COG0030@2|Bacteria,2G6ER@200795|Chloroflexi,34CIF@301297|Dehalococcoidia 301297|Dehalococcoidia J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SRR34280931_k127_344388_0 634956.Geoth_3634 3.342e-153 506.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1WEE2@129337|Geobacillus 91061|Bacilli L Exodeoxyribonuclease V, gamma subunit pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C SRR34280931_k127_344388_3 926550.CLDAP_04380 2.89e-42 168.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi 200795|Chloroflexi M Peptidoglycan-binding LysM - - - - - - - - - - - - LysM,Peptidase_M23,SH3_3 SRR34280931_k127_344388_1 1382356.JQMP01000001_gene1035 2.048e-151 494.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia 189775|Thermomicrobia O Magnesium chelatase, subunit ChlI - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SRR34280931_k127_344388_4 1134413.ANNK01000076_gene3418 8.056e-08 55.0 COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,1ZEEI@1386|Bacillus 91061|Bacilli T COG1734 DnaK suppressor protein yteA - - - - - - - - - - - zf-dskA_traR SRR34280931_k127_371581_4 1444712.BN1013_00934 6.845e-08 58.0 2DPD6@1|root,331K2@2|Bacteria,2JHDM@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 SRR34280931_k127_371581_3 521011.Mpal_1981 4.877e-44 169.0 COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,2N9X7@224756|Methanomicrobia 224756|Methanomicrobia O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K01802,ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase SRR34280931_k127_371581_2 1306174.JODP01000009_gene6579 1.531e-46 179.0 COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria 201174|Actinobacteria I phytoene synthase crtB - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY SRR34280931_k127_371581_0 1123037.AUDE01000002_gene19 1.617e-168 544.0 COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1I0ZZ@117743|Flavobacteriia 976|Bacteroidetes Q FAD dependent oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase SRR34280931_k127_371581_1 865937.Gilli_1908 2.026e-55 204.0 COG0382@1|root,COG0382@2|Bacteria,4NM0C@976|Bacteroidetes,1I0SH@117743|Flavobacteriia 976|Bacteroidetes H UbiA prenyltransferase family - - - - - - - - - - - - UbiA SRR34280931_k127_4048_1 1174504.AJTN02000228_gene1933 3.26e-178 575.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain - - - - - - - - - - - - tRNA-synt_2c,tRNA_SAD SRR34280931_k127_4048_3 237368.SCABRO_00086 9.1e-87 294.0 COG2887@1|root,COG2887@2|Bacteria 2|Bacteria L Belongs to the helicase family. UvrD subfamily - - 3.6.4.12 ko:K10742 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_24,PDDEXK_1 SRR34280931_k127_4048_5 643867.Ftrac_2073 3.707e-82 282.0 COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia 976|Bacteroidetes K PFAM ATP cone domain - - - - - - - - - - - - ATP-cone,Mrr_cat SRR34280931_k127_4048_4 1158610.UC3_02774 7.45e-86 296.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,4AZ76@81852|Enterococcaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans SRR34280931_k127_4048_6 1151292.QEW_1604 7.206e-33 139.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25QDY@186804|Peptostreptococcaceae 186801|Clostridia S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG SRR34280931_k127_4048_8 1906.SFRA_19210 4.326e-07 61.0 COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria 201174|Actinobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released hrdD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR34280931_k127_4048_0 1128398.Curi_c21260 1.438e-306 957.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,2687P@186813|unclassified Clostridiales 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SRR34280931_k127_4048_7 935863.AWZR01000001_gene1762 3.206e-29 128.0 29M6H@1|root,3083Y@2|Bacteria,1RJTC@1224|Proteobacteria,1T7NK@1236|Gammaproteobacteria,1X9GZ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR34280931_k127_4048_2 1444309.JAQG01000026_gene4099 1.109e-118 391.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,26RK6@186822|Paenibacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C SRR34280931_k127_4048_9 673860.AciM339_0292 0.0006801 52.0 COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota 28890|Euryarchaeota O Papain family cysteine protease - - - - - - - - - - - - Peptidase_C1 SRR34280931_k127_429230_2 580327.Tthe_0107 3.694e-45 173.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,42FZQ@68295|Thermoanaerobacterales 186801|Clostridia L TIGRFAM hydrolase, TatD family yabD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SRR34280931_k127_429230_6 1408416.JNJT01000009_gene1280 6.756e-06 54.0 COG0360@1|root,COG0360@2|Bacteria,3WU0T@544448|Tenericutes 544448|Tenericutes J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 SRR34280931_k127_429230_4 555778.Hneap_0025 1.352e-33 134.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1WY0C@135613|Chromatiales 135613|Chromatiales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SRR34280931_k127_429230_5 585524.HMPREF0493_0545 2.197e-12 68.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 SRR34280931_k127_429230_3 546273.VEIDISOL_01176 1.082e-35 143.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H2YZ@909932|Negativicutes 909932|Negativicutes J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C SRR34280931_k127_429230_1 1168067.JAGP01000001_gene1613 2.142e-134 437.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales 72273|Thiotrichales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA SRR34280931_k127_429230_7 240302.BN982_03773 2.999e-05 51.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli 91061|Bacilli O COG1404 Subtilisin-like serine proteases - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,Inhibitor_I9,Peptidase_M6,Peptidase_S8 SRR34280931_k127_429230_0 246194.CHY_1159 1.691e-139 466.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales 186801|Clostridia D PFAM cell divisionFtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SRR34280931_k127_432422_8 1499689.CCNN01000014_gene3111 1.908e-14 79.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,36FE7@31979|Clostridiaceae 186801|Clostridia U Membrane protein insertase, YidC Oxa1 family oxaA - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP SRR34280931_k127_432422_10 321327.CYA_2904 2.09e-05 51.0 COG0594@1|root,COG0594@2|Bacteria,1GP6I@1117|Cyanobacteria,1H2C8@1129|Synechococcus 1117|Cyanobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P SRR34280931_k127_432422_9 929712.KI912613_gene1120 9.491e-09 58.0 COG0230@1|root,COG0230@2|Bacteria,2HH4A@201174|Actinobacteria,4CQS5@84995|Rubrobacteria 84995|Rubrobacteria J Ribosomal protein L34 rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 SRR34280931_k127_432422_2 1540257.JQMW01000011_gene2412 1.595e-105 359.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae 186801|Clostridia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N SRR34280931_k127_432422_5 696281.Desru_0002 3.488e-50 192.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,2611U@186807|Peptococcaceae 186801|Clostridia L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 SRR34280931_k127_432422_1 747365.Thena_0719 2.469e-117 409.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,42EPS@68295|Thermoanaerobacterales 186801|Clostridia M PFAM glycosyl transferase, family 51 - - 2.4.1.129,3.4.16.4 ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase SRR34280931_k127_432422_4 667014.Thein_1915 4.978e-85 298.0 COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SRR34280931_k127_432422_7 1408439.JHXW01000012_gene838 1.431e-34 139.0 COG0817@1|root,COG0817@2|Bacteria,37A4F@32066|Fusobacteria 32066|Fusobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC SRR34280931_k127_432422_6 771875.Ferpe_1384 3.482e-37 146.0 COG0217@1|root,COG0217@2|Bacteria,2GC36@200918|Thermotogae 200918|Thermotogae K transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg SRR34280931_k127_432422_0 1131269.AQVV01000002_gene1185 1.086e-117 389.0 COG2255@1|root,COG2255@2|Bacteria 2|Bacteria L four-way junction helicase activity ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N SRR34280931_k127_432422_3 760142.Hipma_0476 2.075e-104 359.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales 28221|Deltaproteobacteria NU Type II secretion system protein E pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N,cNMP_binding SRR34280931_k127_435270_2 697282.Mettu_1987 4.689e-53 212.0 COG5306@1|root,COG5306@2|Bacteria 2|Bacteria - - exbB2 - 3.4.14.5 ko:K01278,ko:K03561,ko:K12287 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko02044,ko04090,ko04147 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB SRR34280931_k127_435270_6 235985.BBPN01000074_gene7121 5.116e-35 156.0 COG3209@1|root,COG3271@1|root,COG3209@2|Bacteria,COG3271@2|Bacteria,2GMBB@201174|Actinobacteria,2NGBE@228398|Streptacidiphilus 201174|Actinobacteria M Laminin G domain - - - - - - - - - - - - Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat SRR34280931_k127_435270_7 1245469.S58_08750 3.642e-31 143.0 COG0739@1|root,COG3209@1|root,COG0739@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2U4RY@28211|Alphaproteobacteria,3JWRY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS SRR34280931_k127_435270_5 714943.Mucpa_3747 5.197e-37 162.0 COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - CHU_C,Laminin_G_3 SRR34280931_k127_435270_9 1396141.BATP01000003_gene4864 5.91e-16 93.0 COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae 2|Bacteria DEGMUZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins oprH - 3.2.1.4,3.2.1.73 ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449 ko00500,ko01100,ko05133,map00500,map01100,map05133 - R06200,R11307,R11308 - ko00000,ko00001,ko00536,ko01000,ko02000 1.B.14,1.B.14.2,1.B.40.2 GH5,GH9 - Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3 SRR34280931_k127_435270_1 573063.Metin_0396 1.905e-55 201.0 COG0463@1|root,arCOG00895@2157|Archaea 2157|Archaea M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_435270_0 1282360.ABAC460_19840 2.765e-183 586.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM SRR34280931_k127_435270_3 1499967.BAYZ01000017_gene6259 1.507e-41 162.0 COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_435270_10 1198452.Jab_1c10470 3.915e-12 73.0 2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR34280931_k127_435270_4 661478.OP10G_0827 9.727e-41 160.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - 2.1.1.95 ko:K05928 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00112 R07236,R07504,R10491,R10492 RC00003,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 SRR34280931_k127_435270_8 1227739.Hsw_4114 4.334e-31 130.0 COG1807@1|root,COG1807@2|Bacteria,4NKCK@976|Bacteroidetes,47SJB@768503|Cytophagia 976|Bacteroidetes M Tetratricopeptide repeat - - - - - - - - - - - - PMT,TPR_16,TPR_19,TPR_8 SRR34280931_k127_463422_23 1117644.MCANPG14_03310 1.376e-05 51.0 COG0098@1|root,COG0098@2|Bacteria,3WTIC@544448|Tenericutes 544448|Tenericutes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C SRR34280931_k127_463422_13 1129368.SMIPMB4A_v3c6820 8.341e-33 130.0 COG0256@1|root,COG0256@2|Bacteria,3WTJJ@544448|Tenericutes 544448|Tenericutes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p SRR34280931_k127_463422_8 573065.Astex_0960 3.209e-44 166.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,2KFDS@204458|Caulobacterales 204458|Caulobacterales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 SRR34280931_k127_463422_15 2110.MAGa5960 8.121e-32 129.0 COG0096@1|root,COG0096@2|Bacteria,3WTD8@544448|Tenericutes 544448|Tenericutes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 SRR34280931_k127_463422_18 1293054.HSACCH_00074 3.579e-22 96.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3WAWA@53433|Halanaerobiales 186801|Clostridia J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 SRR34280931_k127_463422_6 697281.Mahau_2144 1.883e-49 182.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales 186801|Clostridia J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C SRR34280931_k127_463422_16 345219.Bcoa_1153 3.097e-29 120.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,1ZGZQ@1386|Bacillus 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 SRR34280931_k127_463422_12 944481.JAFP01000001_gene1469 1.315e-36 141.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2M784@213113|Desulfurellales 28221|Deltaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 SRR34280931_k127_463422_20 1232410.KI421428_gene1239 1.592e-15 79.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,43VE7@69541|Desulfuromonadales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 SRR34280931_k127_463422_10 1385514.N782_09525 9.613e-41 154.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,2Y9BB@289201|Pontibacillus 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 SRR34280931_k127_463422_3 1410674.JNKU01000032_gene1099 1.224e-53 196.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C SRR34280931_k127_463422_19 592029.DDD_0537 9.142e-19 90.0 COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia,3HKAE@363408|Nonlabens 976|Bacteroidetes J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 SRR34280931_k127_463422_17 838561.P344_01700 1.099e-26 112.0 COG0185@1|root,COG0185@2|Bacteria,3WTPD@544448|Tenericutes 544448|Tenericutes J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 SRR34280931_k127_463422_2 1158318.ATXC01000001_gene1271 9.884e-88 297.0 COG0090@1|root,COG0090@2|Bacteria,2G3KP@200783|Aquificae 200783|Aquificae J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C SRR34280931_k127_463422_22 290434.BG0492 1.758e-10 66.0 COG0089@1|root,COG0089@2|Bacteria,2J85B@203691|Spirochaetes 203691|Spirochaetes J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 SRR34280931_k127_463422_11 457570.Nther_0195 2.468e-37 150.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia 186801|Clostridia J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 SRR34280931_k127_463422_4 714943.Mucpa_2109 3.385e-53 194.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 SRR34280931_k127_463422_14 1231377.C426_0131 7.142e-32 128.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,1YBPW@1357|Lactococcus 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 SRR34280931_k127_463422_1 1121440.AUMA01000007_gene1292 1.783e-184 584.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SRR34280931_k127_463422_0 986075.CathTA2_2536 1.063e-271 853.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR34280931_k127_463422_7 273068.TTE2297 3.423e-47 174.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,42G2K@68295|Thermoanaerobacterales 186801|Clostridia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 SRR34280931_k127_463422_5 1121289.JHVL01000060_gene2530 9.888e-51 183.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,36IR5@31979|Clostridiaceae 186801|Clostridia J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 SRR34280931_k127_463422_9 880072.Desac_1392 1.567e-42 163.0 COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2X6DV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM peptidase M50 - - - - - - - - - - - - Peptidase_M50 SRR34280931_k127_463422_21 1123070.KB899268_gene2442 1.151e-10 65.0 COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal L28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 SRR34280931_k127_463916_1 1122176.KB903544_gene780 1.632e-98 336.0 COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia 976|Bacteroidetes EGP major facilitator superfamily tetA - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr SRR34280931_k127_463916_0 700598.Niako_0978 1.413e-118 392.0 COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,1IPA7@117747|Sphingobacteriia 976|Bacteroidetes S domain, Protein - - - - - - - - - - - - - SRR34280931_k127_463916_2 1303518.CCALI_00695 5.846e-59 216.0 COG1090@1|root,COG1090@2|Bacteria 2|Bacteria S coenzyme binding - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase SRR34280931_k127_465340_0 1384065.JAGS01000001_gene1617 2.807e-73 260.0 COG2954@1|root,COG3911@1|root,COG2954@2|Bacteria,COG3911@2|Bacteria,1TQK3@1239|Firmicutes,24FBY@186801|Clostridia,3WJKT@541000|Ruminococcaceae 186801|Clostridia S CYTH - - - - - - - - - - - - AAA_28,CYTH SRR34280931_k127_465340_4 470145.BACCOP_03633 0.0005064 46.0 COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,2FTW4@200643|Bacteroidia,4ARA4@815|Bacteroidaceae 976|Bacteroidetes J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p SRR34280931_k127_465340_3 864051.BurJ1DRAFT_4500 5.361e-33 135.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,1KJKB@119065|unclassified Burkholderiales 28216|Betaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N SRR34280931_k127_465340_1 1385513.N780_10435 6.699e-61 226.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,2Y9H3@289201|Pontibacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR34280931_k127_465340_2 1423815.BACR01000006_gene353 1.549e-44 173.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SRR34280931_k127_471034_6 1220534.B655_0767 2.911e-07 56.0 COG0438@1|root,arCOG01403@2157|Archaea 2157|Archaea M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_471034_4 349161.Dred_2202 1.114e-14 86.0 COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_471034_5 1196322.A370_03802 4.963e-09 68.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,36F75@31979|Clostridiaceae 186801|Clostridia M PFAM Glycosyl transferases group 1 - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_471034_1 573063.Metin_1457 1.34e-99 334.0 COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23QBX@183939|Methanococci 183939|Methanococci M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase SRR34280931_k127_471034_3 1499967.BAYZ01000061_gene5932 7.015e-25 118.0 COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferases group 1 - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_471034_7 1121094.KB894664_gene1129 6.614e-06 56.0 COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,2FMXN@200643|Bacteroidia,4AMRY@815|Bacteroidaceae 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 yihX - 3.1.3.10 ko:K07025,ko:K20866 ko00010,ko01120,map00010,map01120 - R00947 RC00078 ko00000,ko00001,ko01000 - - - HAD_2 SRR34280931_k127_471034_0 1565314.OA34_08195 6.555e-113 381.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2YNDI@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR34280931_k127_471034_2 1047013.AQSP01000118_gene1252 1.956e-54 205.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - - SRR34280931_k127_473910_1 243274.THEMA_06225 5.905e-51 186.0 COG0264@1|root,COG0264@2|Bacteria,2GCGY@200918|Thermotogae 200918|Thermotogae J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS SRR34280931_k127_473910_0 1121918.ARWE01000001_gene1940 5.039e-53 195.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,43S78@69541|Desulfuromonadales 28221|Deltaproteobacteria J Ribosomal protein S2 rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 SRR34280931_k127_473910_2 552811.Dehly_0966 4.479e-49 180.0 COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi,34CMR@301297|Dehalococcoidia 301297|Dehalococcoidia J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR34280931_k127_493459_0 702450.CUW_0569 6.936e-84 291.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,3VNZ1@526524|Erysipelotrichia 526524|Erysipelotrichia J Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b,tRNA_edit SRR34280931_k127_493459_1 903814.ELI_1571 2.979e-24 105.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25VUG@186806|Eubacteriaceae 186801|Clostridia M Psort location CytoplasmicMembrane, score rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 SRR34280931_k127_500874_5 379066.GAU_0953 2.807e-06 51.0 2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SRR34280931_k127_500874_4 1243664.CAVL020000032_gene2856 4.817e-07 59.0 2EPT7@1|root,33HDR@2|Bacteria,1VGNH@1239|Firmicutes,4HPGF@91061|Bacilli,1ZJW7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF2231 SRR34280931_k127_500874_3 644966.Tmar_0250 6.15e-18 87.0 COG0640@1|root,COG0640@2|Bacteria,1VPBF@1239|Firmicutes,24VJN@186801|Clostridia 186801|Clostridia K Transcriptional regulator - - - - - - - - - - - - HTH_5 SRR34280931_k127_500874_0 1519464.HY22_07965 2.546e-319 994.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC SRR34280931_k127_500874_1 644282.Deba_1998 3e-128 423.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SRR34280931_k127_500874_2 679200.HMPREF9333_00326 5.4e-61 220.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C SRR34280931_k127_509315_11 317025.Tcr_0336 6.188e-09 65.0 COG1479@1|root,COG2865@1|root,COG3472@1|root,COG1479@2|Bacteria,COG2865@2|Bacteria,COG3472@2|Bacteria,1R4BB@1224|Proteobacteria,1S5C1@1236|Gammaproteobacteria,461CU@72273|Thiotrichales 72273|Thiotrichales K Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 SRR34280931_k127_509315_5 1051632.TPY_0308 3.875e-44 173.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis 186801|Clostridia F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SRR34280931_k127_509315_4 632335.Calkr_0316 2.942e-53 205.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,42ER0@68295|Thermoanaerobacterales 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N SRR34280931_k127_509315_0 411473.RUMCAL_00786 9.183e-291 917.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WGS6@541000|Ruminococcaceae 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SRR34280931_k127_509315_1 1382356.JQMP01000003_gene2339 9.779e-232 735.0 COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia 189775|Thermomicrobia L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB SRR34280931_k127_509315_2 644284.Arch_1786 3.378e-134 439.0 COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4D36Y@85005|Actinomycetales 201174|Actinobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT SRR34280931_k127_509315_7 443143.GM18_3490 3.509e-34 139.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42TNB@68525|delta/epsilon subdivisions,2WQIG@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Peptidyl-prolyl cis-trans fbp - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C SRR34280931_k127_509315_3 123214.PERMA_1590 8.451e-56 203.0 COG1611@1|root,COG1611@2|Bacteria,2G4W3@200783|Aquificae 200783|Aquificae S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox SRR34280931_k127_509315_9 1286171.EAL2_c06910 1.803e-27 115.0 COG2154@1|root,COG2154@2|Bacteria,1VERE@1239|Firmicutes,24NE1@186801|Clostridia 186801|Clostridia H Pterin 4 alpha carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a SRR34280931_k127_509315_10 742767.HMPREF9456_01229 5.036e-14 78.0 COG2259@1|root,COG2259@2|Bacteria,4NSHH@976|Bacteroidetes,2FTHJ@200643|Bacteroidia,22YZR@171551|Porphyromonadaceae 976|Bacteroidetes S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SRR34280931_k127_509315_6 751944.HALDL1_16645 1.675e-43 166.0 arCOG00346@1|root,arCOG00346@2157|Archaea,2XU0A@28890|Euryarchaeota,23V08@183963|Halobacteria 183963|Halobacteria S LUD domain - - - - - - - - - - - - LUD_dom SRR34280931_k127_509315_12 1499680.CCFE01000016_gene1005 1.231e-08 59.0 COG2002@1|root,COG2002@2|Bacteria,1UW6P@1239|Firmicutes,4HZHD@91061|Bacilli,1ZI0K@1386|Bacillus 91061|Bacilli K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin SRR34280931_k127_509315_8 1267580.AF6_0150 5.656e-30 126.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,21V1A@150247|Anoxybacillus 91061|Bacilli K Helix-turn-helix domain sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR34280931_k127_509315_13 1163617.SCD_n01689 2.982e-05 53.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 SRR34280931_k127_53249_1 358396.C445_05218 3.364e-06 53.0 arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,23TMB@183963|Halobacteria 183963|Halobacteria S Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin SRR34280931_k127_53249_0 472759.Nhal_1552 7.538e-30 124.0 2C578@1|root,32RF7@2|Bacteria,1NCG3@1224|Proteobacteria,1STJE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Immunoglobulin-like domain of bacterial spore germination - - - - - - - - - - - - - SRR34280931_k127_53249_2 1249634.D781_0295 0.0006157 48.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 SRR34280931_k127_545378_2 509635.N824_02360 2.286e-22 98.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SRR34280931_k127_545378_1 1236973.JCM9157_1648 7.214e-25 108.0 COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,4HISK@91061|Bacilli,1ZH1U@1386|Bacillus 91061|Bacilli S Nucleotide pyrophosphohydrolase ypjD - - - - - - - - - - - MazG SRR34280931_k127_545378_4 926561.KB900620_gene2883 2.559e-17 85.0 COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia,3WC4Y@53433|Halanaerobiales 186801|Clostridia S phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - DUF429,MazG-like SRR34280931_k127_545378_0 313596.RB2501_09515 5.023e-37 145.0 COG0698@1|root,COG0698@2|Bacteria,4NP5D@976|Bacteroidetes,1I2XE@117743|Flavobacteriia 976|Bacteroidetes G Ribose/Galactose Isomerase - - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB SRR34280931_k127_545378_3 293826.Amet_2777 2.312e-20 100.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,36EV9@31979|Clostridiaceae 186801|Clostridia G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim SRR34280931_k127_549751_1 1087481.AGFX01000011_gene3760 1.447e-32 136.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26S7H@186822|Paenibacillaceae 91061|Bacilli D Belongs to the SEDS family spoVE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE SRR34280931_k127_549751_2 1123508.JH636439_gene853 2.246e-14 81.0 COG2606@1|root,COG2606@2|Bacteria,2J1EW@203682|Planctomycetes 203682|Planctomycetes S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit SRR34280931_k127_549751_0 1382356.JQMP01000004_gene471 7.772e-46 178.0 COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia 189775|Thermomicrobia M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4 SRR34280931_k127_55522_3 1430440.MGMSRv2_1304 9.189e-23 102.0 COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales 204441|Rhodospirillales S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM SRR34280931_k127_55522_0 289376.THEYE_A1953 2.666e-69 247.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,3J0GG@40117|Nitrospirae 40117|Nitrospirae M Belongs to the SIS family. GutQ KpsF subfamily - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS SRR34280931_k127_55522_4 1121439.dsat_0904 1.899e-15 89.0 2AHD9@1|root,317Q9@2|Bacteria,1NQP6@1224|Proteobacteria,42Z2K@68525|delta/epsilon subdivisions,2WUB5@28221|Deltaproteobacteria,2MA29@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SRR34280931_k127_55522_1 647113.Metok_0043 3.441e-69 242.0 COG0500@1|root,arCOG04347@2157|Archaea 2157|Archaea Q Methyltransferase type 11 - - - - - - - - - - - - - SRR34280931_k127_55522_2 1366046.HIMB11_00396 2.296e-42 171.0 COG2244@1|root,COG2244@2|Bacteria,1P4US@1224|Proteobacteria,2UWU2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt SRR34280931_k127_563545_2 452863.Achl_2329 5.688e-20 102.0 COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,1W7V8@1268|Micrococcaceae 201174|Actinobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport SRR34280931_k127_563545_0 479434.Sthe_2028 3.909e-80 283.0 COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SRR34280931_k127_563545_1 555079.Toce_0822 4.817e-65 227.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b SRR34280931_k127_576230_5 1348114.OM33_10505 9.577e-23 103.0 COG4088@1|root,COG4088@2|Bacteria,1R8I1@1224|Proteobacteria,1S2QR@1236|Gammaproteobacteria,2Q25Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F AAA domain - - - - - - - - - - - - AAA_33 SRR34280931_k127_576230_1 1234664.AMRO01000074_gene2877 1.313e-128 422.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1WEAQ@129337|Geobacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD SRR34280931_k127_576230_0 1392487.JIAD01000001_gene1466 9.803e-207 663.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25VFV@186806|Eubacteriaceae 186801|Clostridia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim SRR34280931_k127_576230_3 1131269.AQVV01000002_gene1169 2.085e-67 256.0 COG0072@1|root,COG0072@2|Bacteria 2|Bacteria J phenylalanine-tRNA ligase activity pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind SRR34280931_k127_576230_2 394503.Ccel_1442 2.951e-87 295.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,36DSH@31979|Clostridiaceae 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d SRR34280931_k127_576230_4 1408813.AYMG01000036_gene3303 2.312e-41 168.0 COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,4NH18@976|Bacteroidetes,1IQRP@117747|Sphingobacteriia 976|Bacteroidetes M glycosyl transferase family 2 - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1 SRR34280931_k127_585133_0 247490.KSU1_B0460 1.483e-129 427.0 COG3387@1|root,COG3387@2|Bacteria 2|Bacteria G glucan 1,4-alpha-glucosidase activity - - - - - - - - - - - - Glyco_hydro_15 SRR34280931_k127_585133_1 352165.HMPREF7215_1007 9.966e-88 293.0 COG1449@1|root,COG1449@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 57 family amyA - 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH57 - Glyco_hydro_57 SRR34280931_k127_609843_2 990073.ATHU01000001_gene561 4.68e-54 197.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42RB7@68525|delta/epsilon subdivisions,2YNX1@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC SRR34280931_k127_609843_1 1034807.FBFL15_1309 1.13e-108 368.0 COG3066@1|root,COG3066@2|Bacteria,4NJBM@976|Bacteroidetes,1I0NS@117743|Flavobacteriia,2NYPP@237|Flavobacterium 976|Bacteroidetes L DNA mismatch repair enzyme MutH - - - - - - - - - - - - MutH SRR34280931_k127_609843_0 1250005.PHEL85_3376 8.024e-153 493.0 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia 976|Bacteroidetes H cytosine-specific methyltransferase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase SRR34280931_k127_609843_3 706587.Desti_3035 2.702e-19 96.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2MRUJ@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM Phosphoribosyltransferase - - - - - - - - - - - - Pribosyltran SRR34280931_k127_609843_4 330214.NIDE1348 2.139e-12 76.0 COG4972@1|root,COG4972@2|Bacteria,3J177@40117|Nitrospirae 40117|Nitrospirae NU Type IV pilus assembly protein PilM; - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 SRR34280931_k127_67525_2 1165841.SULAR_09534 6.205e-22 98.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT SRR34280931_k127_67525_3 717231.Flexsi_1964 2.485e-12 71.0 COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres 200930|Deferribacteres S KH domain - - - ko:K06960 - - - - ko00000 - - - KH_4 SRR34280931_k127_67525_4 608538.HTH_1701 9.771e-11 70.0 COG0228@1|root,COG0228@2|Bacteria,2G4A3@200783|Aquificae 200783|Aquificae J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 SRR34280931_k127_67525_0 525373.HMPREF0766_12813 3.477e-197 634.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia 976|Bacteroidetes K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 SRR34280931_k127_67525_1 511051.CSE_12850 5.567e-33 130.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge SRR34280931_k127_684764_2 796942.HMPREF9623_01025 2.652e-30 124.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 186801|Clostridia J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N SRR34280931_k127_684764_13 525903.Taci_1617 3.464e-05 53.0 COG0640@1|root,COG0640@2|Bacteria,3TAVK@508458|Synergistetes 508458|Synergistetes K Transcriptional regulator - - - - - - - - - - - - - SRR34280931_k127_684764_3 1382306.JNIM01000001_gene2994 2.754e-21 102.0 COG0668@1|root,COG0668@2|Bacteria 2|Bacteria M transmembrane transport cmpX - - - - - - - - - - - MS_channel,TM_helix SRR34280931_k127_684764_8 1550091.JROE01000033_gene1245 9.454e-07 51.0 2EKPT@1|root,33EDJ@2|Bacteria,4NYWY@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_684764_12 204536.SULAZ_1633 2.314e-05 47.0 2B9ZZ@1|root,323DM@2|Bacteria 2|Bacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - SRR34280931_k127_684764_14 6669.EFX63806 5.131e-05 46.0 2EAXE@1|root,2SH3N@2759|Eukaryota,3ATGQ@33154|Opisthokonta,3C4FT@33208|Metazoa,3DJWQ@33213|Bilateria 33208|Metazoa - - - - - - - - - - - - - - - SRR34280931_k127_684764_4 679201.HMPREF9334_00001 5.929e-17 81.0 2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes 1239|Firmicutes S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - SRR34280931_k127_684764_5 1123274.KB899431_gene3241 3.879e-15 78.0 2AU0F@1|root,31JKB@2|Bacteria 2|Bacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - SRR34280931_k127_684764_11 5811.TGME49_023480 1.69e-05 57.0 KOG3538@1|root,KOG3539@1|root,KOG3538@2759|Eukaryota,KOG3539@2759|Eukaryota,3YHNR@5794|Apicomplexa,3YJT7@5796|Coccidia,3YTP3@5809|Sarcocystidae 5794|Apicomplexa OW Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) - - - - - - - - - - - - Notch,TSP_1 SRR34280931_k127_684764_9 1168289.AJKI01000029_gene1441 1.804e-06 60.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,3XJ05@558415|Marinilabiliaceae 976|Bacteroidetes S Aerotolerance regulator N-terminal batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA SRR34280931_k127_684764_0 401526.TcarDRAFT_1652 6.995e-67 243.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4H21I@909932|Negativicutes 909932|Negativicutes M Peptidoglycan polymerase that is essential for cell wall elongation rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE SRR34280931_k127_684764_1 767817.Desgi_4565 9.007e-45 177.0 COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_699054_16 472759.Nhal_1552 4.017e-30 124.0 2C578@1|root,32RF7@2|Bacteria,1NCG3@1224|Proteobacteria,1STJE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Immunoglobulin-like domain of bacterial spore germination - - - - - - - - - - - - - SRR34280931_k127_699054_30 1444309.JAQG01000095_gene399 4.041e-06 59.0 COG1664@1|root,COG1664@2|Bacteria,1V1NS@1239|Firmicutes,4HGUF@91061|Bacilli 91061|Bacilli M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin SRR34280931_k127_699054_8 196490.AUEZ01000055_gene235 2.517e-84 283.0 2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria,3JYM4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SRR34280931_k127_699054_21 395019.Bmul_5343 1.082e-23 108.0 2CCI4@1|root,30BPJ@2|Bacteria,1RE42@1224|Proteobacteria,2W4MT@28216|Betaproteobacteria,1K7DA@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR34280931_k127_699054_2 485913.Krac_3439 1.659e-149 488.0 COG1018@1|root,COG1018@2|Bacteria,2G9BE@200795|Chloroflexi 2|Bacteria C PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - - - - - - - - - - FAD_binding_6,NAD_binding_1,NQR2_RnfD_RnfE SRR34280931_k127_699054_7 266835.14026277 9.959e-85 289.0 COG1477@1|root,COG1477@2|Bacteria,1NKWD@1224|Proteobacteria 1224|Proteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE SRR34280931_k127_699054_19 485913.Krac_3441 5.064e-27 118.0 COG3976@1|root,COG3976@2|Bacteria 2|Bacteria S FMN binding - - - - - - - - - - - - FMN_bind SRR34280931_k127_699054_6 883069.HMPREF9238_00263 7.174e-85 310.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4D3X9@85005|Actinomycetales 201174|Actinobacteria P E1-E2 ATPase ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase SRR34280931_k127_699054_5 56780.SYN_00561 9.286e-103 348.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2MQEQ@213462|Syntrophobacterales 28221|Deltaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SRR34280931_k127_699054_22 1410633.JHWR01000010_gene2253 2.157e-19 97.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,27K11@186928|unclassified Lachnospiraceae 186801|Clostridia M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 SRR34280931_k127_699054_11 436717.AOLE_15195 1.331e-51 184.0 COG3324@1|root,COG3324@2|Bacteria,1N3NT@1224|Proteobacteria,1S9KH@1236|Gammaproteobacteria,3NNI8@468|Moraxellaceae 1236|Gammaproteobacteria S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase SRR34280931_k127_699054_33 1121904.ARBP01000005_gene4626 0.0002323 49.0 29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes,47T83@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 SRR34280931_k127_699054_12 1218076.BAYB01000048_gene5876 3.327e-49 179.0 COG4420@1|root,COG4420@2|Bacteria,1P3R0@1224|Proteobacteria,2W6Z4@28216|Betaproteobacteria,1KDBY@119060|Burkholderiaceae 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - SRR34280931_k127_699054_26 1048983.EL17_10185 3.763e-15 82.0 2AEU0@1|root,314R8@2|Bacteria,4P0ZD@976|Bacteroidetes,47TPD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_699054_23 1002672.SAR11G3_01399 7.263e-19 102.0 COG4625@1|root,COG4625@2|Bacteria,1R23M@1224|Proteobacteria,2U6XF@28211|Alphaproteobacteria,4BSR3@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Autotransporter beta-domain - - - - - - - - - - - - Autotransporter,Big_5,DUF285 SRR34280931_k127_699054_15 1442598.JABW01000017_gene1953 6.106e-37 161.0 COG2931@1|root,COG3210@1|root,COG3468@1|root,COG4254@1|root,COG4932@1|root,COG5295@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,43CIF@68525|delta/epsilon subdivisions,2YR7K@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria QU Domain of unknown function (DUF4347) - - - - - - - - - - - - Cadherin,DUF4347,He_PIG SRR34280931_k127_699054_17 1540221.JQNI01000002_gene1602 1.022e-27 126.0 COG0116@1|root,COG0116@2|Bacteria,1WKJG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L RNA methylase family UPF0020 - - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 SRR34280931_k127_699054_32 1340434.AXVA01000005_gene4876 7.927e-05 52.0 2E9GR@1|root,333PV@2|Bacteria,1VK3K@1239|Firmicutes,4HRTZ@91061|Bacilli,1ZKCW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - SRR34280931_k127_699054_25 1110697.NCAST_19_00400 2.409e-17 86.0 COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria,4G5X2@85025|Nocardiaceae 201174|Actinobacteria S Cytochrome C biogenesis protein transmembrane region - - - - - - - - - - - - Cupredoxin_1,DsbD_2,HMA SRR34280931_k127_699054_18 1304865.JAGF01000001_gene2536 1.03e-27 125.0 COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria 201174|Actinobacteria P Cytochrome C biogenesis protein transmembrane region - - - - - - - - - - - - Cupredoxin_1,DsbD_2,HMA SRR34280931_k127_699054_0 290317.Cpha266_2532 1.178e-232 743.0 COG2217@1|root,COG2217@2|Bacteria,1FDP1@1090|Chlorobi 1090|Chlorobi P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase SRR34280931_k127_699054_24 293826.Amet_0044 2.043e-18 87.0 COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes 1239|Firmicutes S Protein conserved in bacteria csoR - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal SRR34280931_k127_699054_14 1123248.KB893337_gene2650 1.154e-40 153.0 2BWTI@1|root,32SZZ@2|Bacteria,4NSVM@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_699054_3 306281.AJLK01000151_gene2055 7.203e-132 431.0 COG0476@1|root,COG0476@2|Bacteria 2|Bacteria H Involved in molybdopterin and thiamine biosynthesis, family 2 - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF SRR34280931_k127_699054_31 1410630.JNKP01000004_gene446 5.104e-05 51.0 COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QJ1@186801|Clostridia,27PJ3@186928|unclassified Lachnospiraceae 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 SRR34280931_k127_699054_20 983548.Krodi_1481 5.361e-27 117.0 COG2856@1|root,COG2856@2|Bacteria,4NYB2@976|Bacteroidetes 976|Bacteroidetes E Pfam:DUF955 - - - - - - - - - - - - Peptidase_M78 SRR34280931_k127_699054_10 760142.Hipma_0827 1.075e-61 229.0 COG1961@1|root,COG1961@2|Bacteria 2|Bacteria L recombinase activity - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom SRR34280931_k127_699054_28 403833.Pmob_1237 8.957e-11 74.0 COG1974@1|root,COG1974@2|Bacteria,2GD29@200918|Thermotogae 200918|Thermotogae K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0032991,GO:0032993,GO:0043565,GO:0097159,GO:1901363 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SRR34280931_k127_699054_4 745310.G432_18425 5.792e-104 350.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SRR34280931_k127_699054_9 1123072.AUDH01000040_gene11 1.003e-81 279.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2JPYW@204441|Rhodospirillales 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SRR34280931_k127_699054_13 1457393.AZ09_04490 4.03e-45 171.0 2E0BM@1|root,32VYT@2|Bacteria,1N3JY@1224|Proteobacteria,2UEBH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S T5orf172 - - - - - - - - - - - - T5orf172 SRR34280931_k127_699054_1 1123487.KB892864_gene2225 9.482e-170 542.0 COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,2VKDY@28216|Betaproteobacteria 28216|Betaproteobacteria O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 SRR34280931_k127_706808_1 1526927.Plano_0004 4.146e-83 303.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26DH7@186818|Planococcaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR SRR34280931_k127_706808_0 65071.PYU1_T011594 1.041e-94 320.0 COG0042@1|root,KOG2335@2759|Eukaryota,1MFAE@121069|Pythiales 121069|Pythiales J TRNA-dihydrouridine synthase - - - - - - - - - - - - Dus SRR34280931_k127_706808_5 1027292.HMPREF9372_2047 4.513e-18 93.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,26F8N@186818|Planococcaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family sdh - - - - - - - - - - - adh_short SRR34280931_k127_706808_4 1216932.CM240_2504 3.838e-22 108.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia,36FGW@31979|Clostridiaceae 186801|Clostridia M PFAM peptidase M15B and M15C, D,D-carboxypeptidase VanY endolysin - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - LysM,PG_binding_1,VanY SRR34280931_k127_706808_2 1205680.CAKO01000040_gene808 5.491e-40 157.0 2AY4N@1|root,31Q6J@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR34280931_k127_706808_3 1410665.JNKR01000008_gene1113 2.098e-25 118.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4H20Z@909932|Negativicutes 909932|Negativicutes S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG SRR34280931_k127_756908_11 1089546.AQUI01000002_gene337 2.23e-08 66.0 COG0438@1|root,COG1216@1|root,COG2227@1|root,COG3064@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG3064@2|Bacteria,2I28T@201174|Actinobacteria,408HY@622450|Actinopolysporales 201174|Actinobacteria HM Methyltransferase small domain - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glycos_transf_2,Methyltransf_31 SRR34280931_k127_756908_10 1357399.HMPREF2087_00488 4.327e-12 76.0 COG2520@1|root,COG2520@2|Bacteria,1N28Y@1224|Proteobacteria,43BVD@68525|delta/epsilon subdivisions 1224|Proteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 SRR34280931_k127_756908_6 1499967.BAYZ01000086_gene5149 2.108e-45 179.0 COG0438@1|root,COG0438@2|Bacteria,2NR76@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SRR34280931_k127_756908_13 573413.Spirs_4234 8.735e-06 54.0 COG2246@1|root,COG2246@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - GtrA SRR34280931_k127_756908_12 1122612.AUBA01000012_gene610 1.39e-06 61.0 COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2USPP@28211|Alphaproteobacteria,2K8AC@204457|Sphingomonadales 204457|Sphingomonadales M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 SRR34280931_k127_756908_5 1353529.M899_1416 2.146e-60 216.0 COG0463@1|root,COG0463@2|Bacteria,1Q5I6@1224|Proteobacteria,431AR@68525|delta/epsilon subdivisions,2WW8Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SRR34280931_k127_756908_0 565034.BHWA1_00145 3.069e-148 475.0 COG1089@1|root,COG1089@2|Bacteria,2J78G@203691|Spirochaetes 203691|Spirochaetes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SRR34280931_k127_756908_2 484770.UFO1_1092 8.931e-112 373.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H35E@909932|Negativicutes 1239|Firmicutes E Belongs to the DegT DnrJ EryC1 family - - 1.17.1.1 ko:K12452 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - DegT_DnrJ_EryC1 SRR34280931_k127_756908_1 1346330.M472_03320 4.303e-124 406.0 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase SRR34280931_k127_756908_8 1131266.ARWQ01000072_gene976 4.009e-21 98.0 COG1051@1|root,arCOG01075@2157|Archaea 2157|Archaea F Nudix hydrolase - - - ko:K03207 - - - - ko00000,ko01000 - - - NUDIX SRR34280931_k127_756908_7 289377.HL41_07900 1.214e-39 161.0 COG0859@1|root,COG0859@2|Bacteria,2GHSG@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 SRR34280931_k127_756908_9 706587.Desti_4723 9.099e-14 80.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,42QYG@68525|delta/epsilon subdivisions,2WN7M@28221|Deltaproteobacteria 28221|Deltaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 SRR34280931_k127_756908_3 1283300.ATXB01000001_gene971 5.139e-62 223.0 COG1442@1|root,COG1442@2|Bacteria,1R5NA@1224|Proteobacteria,1SJX1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - SRR34280931_k127_756908_4 1121033.AUCF01000019_gene3705 2.728e-61 219.0 COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales 204441|Rhodospirillales S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM SRR34280931_k127_761467_2 1038859.AXAU01000010_gene1871 5.819e-07 55.0 2CMAN@1|root,32SE6@2|Bacteria,1RIK0@1224|Proteobacteria,2U9U4@28211|Alphaproteobacteria,3JZGB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_15930 - - - - - - - - - - - - SRR34280931_k127_761467_0 644966.Tmar_0770 1.008e-64 227.0 COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,24EBI@186801|Clostridia 186801|Clostridia S PFAM DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX SRR34280931_k127_761467_1 1090320.KB900605_gene3394 1.778e-21 100.0 COG2940@1|root,COG2940@2|Bacteria,1Q9DE@1224|Proteobacteria,2VDKT@28211|Alphaproteobacteria,2K32C@204457|Sphingomonadales 204457|Sphingomonadales S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET SRR34280931_k127_769348_6 1379270.AUXF01000004_gene3352 8.126e-28 118.0 2ECN0@1|root,336JY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - VPEP SRR34280931_k127_769348_11 1121459.AQXE01000005_gene1559 1.504e-15 87.0 2E3BU@1|root,32YB9@2|Bacteria,1N84T@1224|Proteobacteria,436V7@68525|delta/epsilon subdivisions,2X1J8@28221|Deltaproteobacteria,2MF6C@213115|Desulfovibrionales 28221|Deltaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP SRR34280931_k127_769348_4 313612.L8106_06854 3.358e-53 190.0 COG0080@1|root,COG0080@2|Bacteria,1G4ZJ@1117|Cyanobacteria,1HAME@1150|Oscillatoriales 1117|Cyanobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N SRR34280931_k127_769348_3 555079.Toce_2104 6.525e-62 218.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,42FYD@68295|Thermoanaerobacterales 186801|Clostridia K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG SRR34280931_k127_769348_14 555779.Dthio_PD0340 1.289e-06 52.0 COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MD79@213115|Desulfovibrionales 28221|Deltaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE SRR34280931_k127_769348_7 765420.OSCT_1927 1.77e-26 119.0 COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,377CQ@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL SRR34280931_k127_769348_2 1410632.JHWW01000002_gene2277 7.169e-72 252.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,27IT1@186928|unclassified Lachnospiraceae 186801|Clostridia H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C SRR34280931_k127_769348_9 1354303.M917_1746 2.165e-19 96.0 COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,1SYVW@1236|Gammaproteobacteria,3NTBE@468|Moraxellaceae 1236|Gammaproteobacteria I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 SRR34280931_k127_769348_15 1122609.AUGT01000009_gene3020 0.0003691 51.0 COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria,4DRNY@85009|Propionibacteriales 201174|Actinobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - SRR34280931_k127_769348_12 1123023.JIAI01000011_gene8756 1.478e-14 80.0 COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4E2HU@85010|Pseudonocardiales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily adsA - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR34280931_k127_769348_1 596315.HMPREF0634_0760 1.209e-83 287.0 COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25QYD@186804|Peptostreptococcaceae 186801|Clostridia J S-adenosylmethionine-dependent methyltransferase rlmL_1 - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM SRR34280931_k127_769348_5 1338011.BD94_2877 4.157e-33 134.0 28PI4@1|root,2ZC8A@2|Bacteria,4NMD1@976|Bacteroidetes,1I1WC@117743|Flavobacteriia,34S2C@308865|Elizabethkingia 976|Bacteroidetes S Protein of unknown function (DUF1003) - - - - - - - - - - - - DUF1003 SRR34280931_k127_769348_13 641491.DND132_1113 6.302e-11 72.0 COG0726@1|root,COG0726@2|Bacteria,1NKM8@1224|Proteobacteria,42WTI@68525|delta/epsilon subdivisions,2WP53@28221|Deltaproteobacteria,2MC41@213115|Desulfovibrionales 28221|Deltaproteobacteria G Protein of unknown function (DUF3298) - - - - - - - - - - - - DUF3298,DUF4163 SRR34280931_k127_769348_8 493475.GARC_2376 1.883e-19 96.0 COG3187@1|root,COG3187@2|Bacteria 2|Bacteria O response to heat - - - ko:K03668,ko:K03929 - - - - ko00000,ko01000 - CE10 - META SRR34280931_k127_769348_0 468059.AUHA01000002_gene630 1.493e-216 687.0 COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SRR34280931_k127_769348_10 379066.GAU_0953 1.587e-18 90.0 2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SRR34280931_k127_782578_1 580340.Tlie_1478 1.14e-89 303.0 COG3959@1|root,COG3959@2|Bacteria,3TA23@508458|Synergistetes 508458|Synergistetes G PFAM Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N SRR34280931_k127_782578_0 1121924.ATWH01000014_gene3393 6.252e-108 358.0 COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria,4FKW5@85023|Microbacteriaceae 201174|Actinobacteria G Transketolase, pyrimidine binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SRR34280931_k127_782578_3 1397527.Q670_11880 1.263e-19 90.0 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,1XM5W@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF1653 SRR34280931_k127_782578_2 349521.HCH_06817 5.572e-33 141.0 COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G pfkB family carbohydrate kinase - - - - - - - - - - - - PfkB SRR34280931_k127_792020_7 911045.PSE_3445 1.449e-23 102.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SRR34280931_k127_792020_0 868595.Desca_1452 6.199e-140 460.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae 186801|Clostridia S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 SRR34280931_k127_792020_2 986075.CathTA2_0342 2.388e-83 280.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease SRR34280931_k127_792020_5 1128421.JAGA01000002_gene822 4.04e-30 128.0 COG1385@1|root,COG1385@2|Bacteria 2|Bacteria J rRNA (uridine-N3-)-methyltransferase activity rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA SRR34280931_k127_792020_8 574376.BAMA_20290 5.655e-21 100.0 COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,4IR38@91061|Bacilli,1ZFX1@1386|Bacillus 91061|Bacilli F Phosphoribulokinase / Uridine kinase family - - - - - - - - - - - - PRK SRR34280931_k127_792020_6 457570.Nther_1101 6.753e-26 121.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia 186801|Clostridia D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SRR34280931_k127_792020_3 339860.Msp_0625 9.655e-51 185.0 COG0221@1|root,arCOG01711@2157|Archaea,2XTSU@28890|Euryarchaeota,23P2K@183925|Methanobacteria 183925|Methanobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase SRR34280931_k127_792020_1 1449126.JQKL01000001_gene1375 2.381e-96 329.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,268A5@186813|unclassified Clostridiales 186801|Clostridia K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 SRR34280931_k127_792020_4 1499967.BAYZ01000076_gene830 7.189e-39 156.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - - - - - - - - - - Thioredoxin_4 SRR34280931_k127_792020_9 1267533.KB906737_gene1537 1.681e-14 88.0 COG3055@1|root,COG3485@1|root,COG3055@2|Bacteria,COG3485@2|Bacteria,3Y8A3@57723|Acidobacteria 57723|Acidobacteria Q protocatechuate 3,4-dioxygenase - - - - - - - - - - - - - SRR34280931_k127_819535_0 552811.Dehly_0200 5.561e-55 206.0 COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi,34D15@301297|Dehalococcoidia 301297|Dehalococcoidia H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf SRR34280931_k127_819535_2 29540.C481_03672 7.842e-17 86.0 COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria 183963|Halobacteria J Belongs to the eIF-2B alpha beta delta subunits family tif2Ba - - - - - - - - - - - IF-2B,NUDIX SRR34280931_k127_819535_1 673862.BABL1_430 1.384e-26 121.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Belongs to the GPI family pgi - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI SRR34280931_k127_819660_1 926566.Terro_2826 6.16e-53 203.0 COG2148@1|root,COG2148@2|Bacteria,3Y3GZ@57723|Acidobacteria,2JIAU@204432|Acidobacteriia 204432|Acidobacteriia M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf SRR34280931_k127_819660_0 321332.CYB_1758 1.243e-90 317.0 COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria,1GYPU@1129|Synechococcus 1117|Cyanobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SRR34280931_k127_819660_2 525904.Tter_0080 1.127e-49 189.0 COG0341@1|root,COG0341@2|Bacteria,2NP4P@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SRR34280931_k127_819660_8 4113.PGSC0003DMT400052301 0.0001209 45.0 2E4EA@1|root,2S5QZ@2759|Eukaryota,37X8Y@33090|Viridiplantae,3GKGJ@35493|Streptophyta,44UAV@71274|asterids 35493|Streptophyta - - - - - - - - - - - - - - - SRR34280931_k127_819660_5 1408438.JADD01000030_gene1244 1.597e-11 66.0 2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - SRR34280931_k127_819660_4 4113.PGSC0003DMT400048624 1.784e-12 69.0 2E4EA@1|root,2S5QZ@2759|Eukaryota,389WA@33090|Viridiplantae,3GYYM@35493|Streptophyta,44TE1@71274|asterids 35493|Streptophyta - - - - - - - - - - - - - - - SRR34280931_k127_819660_7 927658.AJUM01000034_gene415 3.781e-06 49.0 2EK6X@1|root,33DXA@2|Bacteria,4NY6H@976|Bacteroidetes,2G29J@200643|Bacteroidia,3XKG0@558415|Marinilabiliaceae 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_819660_3 1123058.KB894221_gene942 1.78e-15 78.0 2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SRR34280931_k127_833767_0 1185876.BN8_05885 1.256e-61 222.0 COG1004@1|root,COG1004@2|Bacteria 2|Bacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR34280931_k127_833767_2 1165841.SULAR_10644 2.674e-35 145.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P SRR34280931_k127_833767_1 5127.CCT67725 2.235e-52 191.0 COG1087@1|root,KOG1371@2759|Eukaryota,39KCQ@33154|Opisthokonta,3PBHS@4751|Fungi,3RN10@4890|Ascomycota,21D2X@147550|Sordariomycetes,3TKEP@5125|Hypocreales,1FVEQ@110618|Nectriaceae 4751|Fungi M RmlD substrate binding domain - - - - - - - - - - - - GDP_Man_Dehyd SRR34280931_k127_836606_0 246194.CHY_0169 1.284e-16 91.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales 186801|Clostridia D PFAM Peptidase M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SRR34280931_k127_878627_0 1123073.KB899241_gene2772 1.61e-43 164.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1X5XQ@135614|Xanthomonadales 135614|Xanthomonadales S EVE domain-containing protein - - - - - - - - - - - - EVE SRR34280931_k127_878627_1 56780.SYN_00359 1.998e-40 158.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2X6X9@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 SRR34280931_k127_878627_2 566461.SSFG_00407 2.069e-38 152.0 COG1651@1|root,COG1651@2|Bacteria,2GM6C@201174|Actinobacteria 201174|Actinobacteria O DSBA oxidoreductase - - - - - - - - - - - - Thioredoxin_4 SRR34280931_k127_878627_3 1380390.JIAT01000009_gene1331 1.889e-10 68.0 COG4243@1|root,COG4243@2|Bacteria,2HGRK@201174|Actinobacteria,4CSQE@84995|Rubrobacteria 84995|Rubrobacteria S VKc - - - - - - - - - - - - VKOR SRR34280931_k127_878627_4 1033734.CAET01000025_gene1061 8.15e-08 54.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli,1ZCR7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C SRR34280931_k127_887027_1 660470.Theba_2351 1.579e-22 115.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CARDB,Cadherin-like,DUF4091 SRR34280931_k127_887027_4 933262.AXAM01000021_gene479 7.428e-12 79.0 COG1075@1|root,COG1404@1|root,COG2304@1|root,COG3507@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3507@2|Bacteria,1NDGA@1224|Proteobacteria,43DCN@68525|delta/epsilon subdivisions,2WRRD@28221|Deltaproteobacteria,2MME4@213118|Desulfobacterales 28221|Deltaproteobacteria G von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA SRR34280931_k127_887027_2 1163617.SCD_n01120 2.168e-21 105.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria 28216|Betaproteobacteria K RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR34280931_k127_887027_0 28115.HR11_07100 2.998e-46 179.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia,22XDM@171551|Porphyromonadaceae 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR34280931_k127_887027_3 797515.HMPREF9103_00964 7.524e-16 83.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 SRR34280931_k127_90491_3 1121957.ATVL01000008_gene4668 0.0001116 51.0 COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia 976|Bacteroidetes L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N SRR34280931_k127_90491_0 1487921.DP68_00245 1.206e-228 749.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,36DSA@31979|Clostridiaceae 186801|Clostridia J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 SRR34280931_k127_90491_1 1120999.JONM01000006_gene2456 4.439e-40 156.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,2KQYH@206351|Neisseriales 206351|Neisseriales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin SRR34280931_k127_90491_2 997350.HMPREF9129_2037 2.967e-34 139.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,22G03@1570339|Peptoniphilaceae 186801|Clostridia J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR34280931_k127_908627_1 1536775.H70737_15445 0.0005654 52.0 COG0741@1|root,COG3291@1|root,COG4733@1|root,COG0741@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1UNRD@1239|Firmicutes,4IUMD@91061|Bacilli,277P3@186822|Paenibacillaceae 91061|Bacilli M Immunoglobulin - - - - - - - - - - - - Cu_amine_oxidN1,Flg_new,He_PIG SRR34280931_k127_908627_0 1122128.AUEE01000023_gene1389 6.134e-46 173.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,4GXPP@90964|Staphylococcaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SRR34280931_k127_98973_0 525904.Tter_1614 3.335e-70 255.0 COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding Protein dimerisation domain ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PASTA,PBP_dimer,Transpeptidase SRR34280931_k127_98973_1 720554.Clocl_2423 2.4e-65 241.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR34280931_k127_98973_2 4932.Q0055 7.258e-05 52.0 COG3344@1|root,KOG4768@2759|Eukaryota,39UKU@33154|Opisthokonta,3P0IZ@4751|Fungi,3QZIF@4890|Ascomycota 4751|Fungi A encoded by a mobile group II intron within the mitochondrial COX1 gene - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003964,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006278,GO:0006310,GO:0006314,GO:0006315,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - - - - - - - - - - Intron_maturas2,RVT_1 ## 568 queries scanned ## Total time (seconds): 3.6994268894195557 ## Rate: 153.54 q/s