## Tue Dec 16 03:32:10 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR34280931_bin.8.fa -m mmseqs --itype genome -o SRR34280931_bin.8 --output_dir /data/result/bins/wyx/egg/SRR34280931_bin.8 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR34280931_k127_1005248_88	330214.NIDE3364	1.034e-152	488.0	COG4974@1|root,COG4974@2|Bacteria,3J0KV@40117|Nitrospirae	40117|Nitrospirae	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR34280931_k127_1005248_15	330214.NIDE3365	0.0	1202.0	COG0683@1|root,COG0683@2|Bacteria,3J18U@40117|Nitrospirae	40117|Nitrospirae	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR34280931_k127_1005248_55	330214.NIDE3366	5.408e-207	645.0	COG0180@1|root,COG0180@2|Bacteria,3J0A0@40117|Nitrospirae	40117|Nitrospirae	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR34280931_k127_1005248_134	330214.NIDE3368	2.178e-75	256.0	COG1259@1|root,COG1259@2|Bacteria	2|Bacteria	K	PFAM Uncharacterised ACR, COG1259	yqdE	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
SRR34280931_k127_1005248_102	330214.NIDE3370	2.573e-130	416.0	COG0491@1|root,COG0491@2|Bacteria,3J0VN@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR34280931_k127_1005248_185	316274.Haur_1994	1.045e-30	133.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,NACHT
SRR34280931_k127_1005248_75	330214.NIDE3374	1.123e-180	574.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_125	330214.NIDE3376	7.851e-86	288.0	2ETMV@1|root,33M5M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRR34280931_k127_1005248_197	517417.Cpar_0534	1.467e-21	97.0	COG3668@1|root,COG3668@2|Bacteria,1FFP3@1090|Chlorobi	1090|Chlorobi	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR34280931_k127_1005248_208	497965.Cyan7822_1093	7.246e-12	67.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,3KKC0@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR34280931_k127_1005248_112	330214.NIDE3844	9.383e-105	342.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR34280931_k127_1005248_189	395963.Bind_2909	1.251e-28	122.0	2E4QW@1|root,32ZJG@2|Bacteria,1N8H1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3995)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3995
SRR34280931_k127_1005248_128	344747.PM8797T_04660	6.546e-82	278.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR34280931_k127_1005248_150	717785.HYPMC_2180	4.504e-59	213.0	2E9TF@1|root,333ZG@2|Bacteria,1NQ16@1224|Proteobacteria,2UR81@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	MUG113
SRR34280931_k127_1005248_174	290317.Cpha266_0257	4.745e-37	140.0	COG4974@1|root,COG4974@2|Bacteria,1FESB@1090|Chlorobi	1090|Chlorobi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR34280931_k127_1005248_215	330214.NIDE3382	3.193e-07	53.0	2ECCV@1|root,336B4@2|Bacteria,3J18G@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_25	330214.NIDE3383	1.579e-312	960.0	COG0493@1|root,COG0493@2|Bacteria,3J152@40117|Nitrospirae	40117|Nitrospirae	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,GXGXG,Pyr_redox_2,Pyr_redox_3
SRR34280931_k127_1005248_1	330214.NIDE3384	0.0	2983.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,3J0SV@40117|Nitrospirae	40117|Nitrospirae	C	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR34280931_k127_1005248_54	330214.NIDE3385	3.259e-212	660.0	COG0142@1|root,COG0142@2|Bacteria,3J0H0@40117|Nitrospirae	40117|Nitrospirae	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR34280931_k127_1005248_38	330214.NIDE3386	3.361e-260	804.0	COG4198@1|root,COG4198@2|Bacteria,3J0IE@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR34280931_k127_1005248_31	330214.NIDE3387	5.886e-276	851.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1005248_96	330214.NIDE3388	2.045e-136	438.0	COG1208@1|root,COG1208@2|Bacteria,3J0QW@40117|Nitrospirae	40117|Nitrospirae	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR34280931_k127_1005248_56	330214.NIDE3389	2.69e-205	642.0	COG3178@1|root,COG3178@2|Bacteria,3J15Y@40117|Nitrospirae	40117|Nitrospirae	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR34280931_k127_1005248_68	330214.NIDE3390	4.797e-187	595.0	COG0667@1|root,COG0667@2|Bacteria,3J154@40117|Nitrospirae	40117|Nitrospirae	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR34280931_k127_1005248_158	330214.NIDE3391	6.57e-55	197.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR34280931_k127_1005248_8	330214.NIDE3392	0.0	1399.0	COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SRR34280931_k127_1005248_53	330214.NIDE3393	1.099e-212	663.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR34280931_k127_1005248_181	330214.NIDE3395	5.321e-31	125.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_1005248_67	330214.NIDE3396	1.823e-188	591.0	COG0037@1|root,COG0037@2|Bacteria,3J0JK@40117|Nitrospirae	40117|Nitrospirae	H	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR34280931_k127_1005248_222	1003200.AXXA_04603	0.0002003	45.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,3T5MT@506|Alcaligenaceae	28216|Betaproteobacteria	K	Regulatory protein Ada 2	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR34280931_k127_1005248_155	1278073.MYSTI_02336	2.256e-57	214.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR34280931_k127_1005248_221	1114970.PSF113_2490	0.0001531	49.0	COG0346@1|root,COG0346@2|Bacteria,1N7AJ@1224|Proteobacteria,1RU89@1236|Gammaproteobacteria,1YQ70@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR34280931_k127_1005248_217	754027.HMPREF9554_00985	7.004e-07	55.0	COG4733@1|root,COG4733@2|Bacteria,2JBHZ@203691|Spirochaetes	203691|Spirochaetes	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,fn3
SRR34280931_k127_1005248_51	330214.NIDE3398	7.946e-215	674.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	thuE	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
SRR34280931_k127_1005248_83	330214.NIDE3399	4.563e-168	532.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	thuF	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02025,ko:K10237,ko:K15771	ko02010,map02010	M00204,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2	-	iNJ661.Rv1236	BPD_transp_1
SRR34280931_k127_1005248_86	330214.NIDE3400	4.317e-155	504.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR34280931_k127_1005248_77	330214.NIDE3401	1.001e-179	568.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR34280931_k127_1005248_63	330214.NIDE3402	9.158e-191	599.0	COG0484@1|root,COG0484@2|Bacteria,3J0A7@40117|Nitrospirae	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR34280931_k127_1005248_108	330214.NIDE3403	1.013e-109	359.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR34280931_k127_1005248_110	330214.NIDE3404	4.05e-106	346.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR34280931_k127_1005248_157	330214.NIDE3405	1.098e-55	199.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	Z012_07375	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRR34280931_k127_1005248_19	330214.NIDE3406	0.0	1079.0	COG0129@1|root,COG0129@2|Bacteria,3J0ES@40117|Nitrospirae	40117|Nitrospirae	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR34280931_k127_1005248_81	330214.NIDE3407	1.631e-175	553.0	2DME8@1|root,32QX1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_9	330214.NIDE3408	0.0	1383.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	iJN746.PP_5217	PP_kinase,PP_kinase_C,PP_kinase_N
SRR34280931_k127_1005248_214	330214.NIDE3409	2.076e-07	56.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR34280931_k127_1005248_44	330214.NIDE3411	1.611e-237	738.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3411|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_13	330214.NIDE3413	0.0	1256.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA
SRR34280931_k127_1005248_171	330214.NIDE3414	5.955e-40	150.0	COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_1005248_52	330214.NIDE3417	7.864e-213	667.0	COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_1005248_47	330214.NIDE3418	1.805e-226	705.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_1005248_34	330214.NIDE3419	1.568e-265	820.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
SRR34280931_k127_1005248_60	330214.NIDE3420	6.05e-196	614.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR34280931_k127_1005248_79	330214.NIDE3421	3.929e-177	562.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR34280931_k127_1005248_115	357808.RoseRS_4439	1.066e-102	357.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,374YC@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_1005248_164	756067.MicvaDRAFT_4924	1.831e-46	181.0	COG0500@1|root,COG0500@2|Bacteria,COG2226@2|Bacteria,1G38U@1117|Cyanobacteria,1H9F3@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Sulfotransfer_1
SRR34280931_k127_1005248_153	1524467.IV04_08905	5.758e-58	219.0	COG1835@1|root,COG1835@2|Bacteria,1PGYS@1224|Proteobacteria,1SXK8@1236|Gammaproteobacteria,404AY@613|Serratia	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR34280931_k127_1005248_190	622637.KE124774_gene2646	1.606e-27	126.0	COG0500@1|root,COG3391@1|root,COG2226@2|Bacteria,COG3391@2|Bacteria,1N2N4@1224|Proteobacteria,2UDEU@28211|Alphaproteobacteria,370RC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR34280931_k127_1005248_17	402777.KB235904_gene4269	0.0	1119.0	COG0438@1|root,COG1196@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1196@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1FZUY@1117|Cyanobacteria,1H86A@1150|Oscillatoriales	1117|Cyanobacteria	DM	Glycosyl transferase, group	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_31,Sulfotransfer_3
SRR34280931_k127_1005248_133	196367.JNFG01000198_gene2304	5.896e-76	266.0	COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,1MX5Z@1224|Proteobacteria,2VJUA@28216|Betaproteobacteria,1K10J@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	glycosyl transferase family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Capsule_synth,Glyco_tran_WbsX,Glyco_tranf_2_3,Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_23,RgpF
SRR34280931_k127_1005248_120	330214.NIDE3431	1.63e-96	321.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Nitroreductase
SRR34280931_k127_1005248_72	330214.NIDE3432	4.562e-182	582.0	COG1134@1|root,COG1134@2|Bacteria,3J142@40117|Nitrospirae	40117|Nitrospirae	GM	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
SRR34280931_k127_1005248_195	994573.T472_0210545	4.02e-24	112.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,36W8R@31979|Clostridiaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR34280931_k127_1005248_101	330214.NIDE3434	2.02e-130	419.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR34280931_k127_1005248_73	330214.NIDE3435	3.207e-181	570.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_1005248_87	330214.NIDE3436	1.652e-154	494.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3436|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_28	330214.NIDE3437	3.373e-300	934.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
SRR34280931_k127_1005248_144	330214.NIDE3438	4.52e-65	228.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
SRR34280931_k127_1005248_127	330214.NIDE3439	4.201e-82	275.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
SRR34280931_k127_1005248_20	330214.NIDE3440	0.0	1032.0	COG0457@1|root,COG0457@2|Bacteria,3J0MH@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SRR34280931_k127_1005248_33	330214.NIDE3441	5.243e-271	838.0	COG0305@1|root,COG0305@2|Bacteria,3J0EZ@40117|Nitrospirae	40117|Nitrospirae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR34280931_k127_1005248_62	330214.NIDE3442	1.228e-192	606.0	COG3705@1|root,COG3705@2|Bacteria,3J13R@40117|Nitrospirae	40117|Nitrospirae	E	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR34280931_k127_1005248_21	330214.NIDE3443	0.0	1010.0	COG0111@1|root,COG4747@1|root,COG0111@2|Bacteria,COG4747@2|Bacteria,3J0DZ@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR34280931_k127_1005248_45	330214.NIDE3444	3.239e-237	736.0	COG0075@1|root,COG0075@2|Bacteria,3J0FC@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR34280931_k127_1005248_40	330214.NIDE3445	2.632e-245	764.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3J0J4@40117|Nitrospirae	40117|Nitrospirae	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR34280931_k127_1005248_91	330214.NIDE3446	8.367e-150	477.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SRR34280931_k127_1005248_58	330214.NIDE3447	2.322e-198	625.0	COG0156@1|root,COG0156@2|Bacteria,3J0XU@40117|Nitrospirae	2|Bacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.bioF,iNJ661.Rv1569	Aminotran_1_2
SRR34280931_k127_1005248_48	330214.NIDE3448	4.711e-224	695.0	COG2805@1|root,COG2805@2|Bacteria,3J0YS@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR34280931_k127_1005248_42	330214.NIDE3449	1.13e-243	754.0	COG5008@1|root,COG5008@2|Bacteria	2|Bacteria	NU	twitching motility protein	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR34280931_k127_1005248_135	330214.NIDE3450	2.475e-75	256.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixO
SRR34280931_k127_1005248_94	330214.NIDE3451	7.705e-143	461.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_1005248_139	330214.NIDE3452	8.885e-72	248.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DDE_Tnp_IS66,DUF3102,DUF3450,KfrA_N,Methyltransf_21
SRR34280931_k127_1005248_0	330214.NIDE3454	0.0	3047.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR34280931_k127_1005248_46	330214.NIDE3456	2.239e-233	729.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	hlyD	-	-	ko:K02022,ko:K11003,ko:K12532	ko02020,ko03070,ko05133,map02020,map03070,map05133	M00325,M00326,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1,8.A.1.3.1,8.A.1.3.2	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
SRR34280931_k127_1005248_16	330214.NIDE3457	0.0	1176.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	hlyB	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR34280931_k127_1005248_123	330214.NIDE3460	1.184e-86	290.0	COG3040@1|root,COG3040@2|Bacteria	2|Bacteria	M	lipid binding	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
SRR34280931_k127_1005248_207	1125863.JAFN01000001_gene3137	4.971e-12	75.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1005248_14	330214.NIDE3462	0.0	1207.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9
SRR34280931_k127_1005248_12	330214.NIDE3464	0.0	1291.0	COG0296@1|root,COG0296@2|Bacteria,3J0WY@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR34280931_k127_1005248_82	330214.NIDE3467	1.9e-175	559.0	COG3673@1|root,COG3673@2|Bacteria	2|Bacteria	M	conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
SRR34280931_k127_1005248_186	1121438.JNJA01000061_gene3336	2.832e-30	123.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MGH2@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR34280931_k127_1005248_61	1288494.EBAPG3_430	8.215e-195	619.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,372JJ@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRR34280931_k127_1005248_2	330214.NIDE3474	0.0	1904.0	COG0841@1|root,COG0841@2|Bacteria,3J0FA@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138,ko:K19585	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00767	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.47	-	-	ACR_tran
SRR34280931_k127_1005248_49	330214.NIDE3475	3.49e-218	681.0	COG0845@1|root,COG0845@2|Bacteria,3J10X@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR34280931_k127_1005248_113	330214.NIDE3478	2.629e-104	343.0	29IJ4@1|root,313M6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR34280931_k127_1005248_162	1502851.FG93_04366	8.649e-52	186.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,3JZ56@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR34280931_k127_1005248_138	330214.NIDE3480	7.704e-72	249.0	COG3865@1|root,COG3865@2|Bacteria,3J19H@40117|Nitrospirae	40117|Nitrospirae	H	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR34280931_k127_1005248_166	330214.NIDE3483	4.711e-44	164.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
SRR34280931_k127_1005248_169	330214.NIDE3481	1.087e-41	155.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR34280931_k127_1005248_41	330214.NIDE3482	6.559e-244	756.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR34280931_k127_1005248_161	330214.NIDE3484	1.657e-52	187.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR34280931_k127_1005248_147	330214.NIDE3485	1.159e-63	220.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR34280931_k127_1005248_212	323850.Shew_1307	5.062e-08	56.0	2BRAN@1|root,32K96@2|Bacteria,1P197@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_192	323850.Shew_1307	3.526e-26	113.0	2BRAN@1|root,32K96@2|Bacteria,1P197@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_148	330214.NIDE3486	1.241e-62	218.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR34280931_k127_1005248_182	479434.Sthe_2955	7.551e-31	123.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1005248_119	582515.KR51_00002240	4.296e-97	324.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR34280931_k127_1005248_216	469383.Cwoe_3041	6.183e-07	58.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR34280931_k127_1005248_180	748247.AZKH_4105	1.564e-31	127.0	COG2929@1|root,COG2929@2|Bacteria,1N8PW@1224|Proteobacteria,2W408@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
SRR34280931_k127_1005248_194	261292.Nit79A3_0541	4.9e-26	110.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria,2W4RK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_50	330214.NIDE3487	1.35e-217	681.0	COG4941@1|root,COG4941@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1005248_159	330214.NIDE3488	6.949e-53	188.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	DUF1858,FeS_assembly_P
SRR34280931_k127_1005248_71	330214.NIDE3489	5.961e-183	579.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR34280931_k127_1005248_145	330214.NIDE3490	1.892e-64	226.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
SRR34280931_k127_1005248_165	1116472.MGMO_37c00430	4.526e-46	169.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,1SDT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
SRR34280931_k127_1005248_143	1382359.JIAL01000001_gene698	1.278e-68	237.0	2B5NQ@1|root,31YI3@2|Bacteria,3Y9FC@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR34280931_k127_1005248_176	330214.NIDE3499	1.438e-35	138.0	2C7J2@1|root,33AYB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_121	330214.NIDE3500	1.704e-96	321.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR34280931_k127_1005248_26	330214.NIDE3501	4.343e-306	946.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR34280931_k127_1005248_191	1123393.KB891316_gene1578	1.317e-26	114.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2VT3J@28216|Betaproteobacteria,1KT7S@119069|Hydrogenophilales	119069|Hydrogenophilales	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR34280931_k127_1005248_184	330214.NIDE3506	9.637e-31	130.0	COG3558@1|root,COG3558@2|Bacteria,3J19G@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRR34280931_k127_1005248_106	63737.Npun_R0239	8.593e-113	375.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR34280931_k127_1005248_183	330214.NIDE3502	8.281e-31	125.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
SRR34280931_k127_1005248_141	330214.NIDE3507	5.408e-69	239.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	rimL	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR34280931_k127_1005248_160	1116232.AHBF01000137_gene1871	9.005e-53	204.0	COG1231@1|root,COG1231@2|Bacteria,2I8ZQ@201174|Actinobacteria	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR34280931_k127_1005248_167	153948.NAL212_2760	1.959e-43	166.0	2AI5X@1|root,318K6@2|Bacteria,1PW2Z@1224|Proteobacteria,2WBP3@28216|Betaproteobacteria,373HR@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_64	768670.Calni_0859	1.301e-190	629.0	COG1520@1|root,COG3391@1|root,COG4249@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR34280931_k127_1005248_95	331678.Cphamn1_1381	2.08e-142	463.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR34280931_k127_1005248_35	331678.Cphamn1_1380	1.468e-263	827.0	COG0457@1|root,COG0457@2|Bacteria	331678.Cphamn1_1380|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_218	62928.azo3973	6.558e-06	49.0	COG3179@1|root,COG3409@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	exeA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	-	ko:K02450,ko:K03791,ko:K17733	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko01011,ko02044	9.B.42	GH19	-	AAA_22,Glyco_hydro_19,PG_binding_1
SRR34280931_k127_1005248_97	330214.NIDE3510	2.696e-134	440.0	2DT3N@1|root,33IIR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_111	330214.NIDE3764	8.715e-106	351.0	28PNA@1|root,2ZCB3@2|Bacteria	2|Bacteria	S	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR34280931_k127_1005248_85	1122604.JONR01000045_gene2483	4.119e-159	516.0	2DBEC@1|root,2Z8RY@2|Bacteria,1MXRI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
SRR34280931_k127_1005248_57	330214.NIDE3513	6.448e-205	640.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR34280931_k127_1005248_114	330214.NIDE3514	4.301e-104	342.0	COG0546@1|root,COG0546@2|Bacteria,3J11X@40117|Nitrospirae	40117|Nitrospirae	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_5	330214.NIDE3515	0.0	1568.0	COG3957@1|root,COG3957@2|Bacteria,3J10J@40117|Nitrospirae	40117|Nitrospirae	H	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR34280931_k127_1005248_93	1123393.KB891326_gene93	1.58e-143	466.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,1KRJW@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Acetokinase family	-	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR34280931_k127_1005248_3	330214.NIDE2212	0.0	1769.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TIR_2,TPR_12
SRR34280931_k127_1005248_99	330214.NIDE2211	1.793e-133	432.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	rmlA	GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.7.13,2.7.7.24,2.7.7.99	ko:K00966,ko:K00973,ko:K00992	ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130	M00114,M00361,M00362,M00793	R00885,R02328,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRR34280931_k127_1005248_59	330214.NIDE2210	3.187e-198	624.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4	ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515	ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100	M00037	R03130,R04905,R10060,R10061	RC00003,RC00392,RC03038,RC03040	ko00000,ko00001,ko00002,ko01000,ko01008,ko03009	-	-	-	AMP-binding,Aminotran_1_2,AviRa,Condensation,Dimerisation2,Hen1_L,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding
SRR34280931_k127_1005248_36	330214.NIDE2209	3.093e-262	813.0	COG0014@1|root,COG0014@2|Bacteria,3J0ET@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR34280931_k127_1005248_175	330214.NIDE2192	5.314e-36	139.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	ArsP_1,Zip
SRR34280931_k127_1005248_193	330214.NIDE2190	4.387e-26	114.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR34280931_k127_1005248_156	330214.NIDE2189	4.255e-56	207.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR34280931_k127_1005248_131	330214.NIDE2188	3.683e-80	271.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K07165	-	-	-	-	ko00000,ko03021	-	-	-	DUF4974,FecR,Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1005248_117	330214.NIDE2185	5.992e-100	336.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
SRR34280931_k127_1005248_6	330214.NIDE2183	0.0	1518.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,STN,TonB_dep_Rec
SRR34280931_k127_1005248_66	330214.NIDE2177	6.902e-189	601.0	COG3182@1|root,COG3182@2|Bacteria	2|Bacteria	E	Iron-regulated membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
SRR34280931_k127_1005248_146	330214.NIDE2176	7.366e-64	224.0	COG0735@1|root,COG0735@2|Bacteria,3J0UN@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR34280931_k127_1005248_129	330214.NIDE2175	1.375e-81	275.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1005248_105	330214.NIDE2174	1.65e-116	384.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
SRR34280931_k127_1005248_11	330214.NIDE2173	0.0	1358.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,STN,TonB_dep_Rec
SRR34280931_k127_1005248_142	330214.NIDE2168	6.661e-69	236.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR34280931_k127_1005248_199	387092.NIS_1423	4.29e-21	97.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2YQ7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR34280931_k127_1005248_90	330214.NIDE2166	1.277e-151	486.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR34280931_k127_1005248_80	330214.NIDE2164	1.01e-176	561.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA_2	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR34280931_k127_1005248_4	330214.NIDE2163	0.0	1623.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR34280931_k127_1005248_173	1190606.AJYG01000173_gene520	1.656e-37	149.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,1STA5@1236|Gammaproteobacteria,1XXNZ@135623|Vibrionales	135623|Vibrionales	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
SRR34280931_k127_1005248_172	118163.Ple7327_2770	4.072e-38	152.0	COG5485@1|root,COG5485@2|Bacteria,1G620@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR34280931_k127_1005248_43	330214.NIDE2208	1.758e-238	751.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
SRR34280931_k127_1005248_74	330214.NIDE2207	5.865e-181	571.0	COG2008@1|root,COG2008@2|Bacteria	2|Bacteria	E	L-allo-threonine aldolase activity	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR34280931_k127_1005248_89	330214.NIDE2205	8.72e-152	482.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K17882	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	KNTase_C,NTP_transf_2
SRR34280931_k127_1005248_69	330214.NIDE2204	1.293e-186	584.0	COG1023@1|root,COG1023@2|Bacteria	2|Bacteria	G	D-gluconate metabolic process	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR34280931_k127_1005248_23	330214.NIDE2203	1.719e-316	972.0	COG0364@1|root,COG0364@2|Bacteria,3J0XD@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR34280931_k127_1005248_163	330214.NIDE2202	1.112e-48	176.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR34280931_k127_1005248_116	330214.NIDE2201	7.235e-101	332.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR34280931_k127_1005248_24	330214.NIDE2200	5.799e-315	975.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,PT-HINT,Sulfatase
SRR34280931_k127_1005248_27	330214.NIDE2199	7.375e-305	940.0	COG2206@1|root,COG2206@2|Bacteria,3J14V@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD
SRR34280931_k127_1005248_118	330214.NIDE2197	3.324e-99	327.0	COG2825@1|root,COG2825@2|Bacteria,3J1AH@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR34280931_k127_1005248_70	330214.NIDE2196	1.785e-184	581.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SRR34280931_k127_1005248_152	330214.NIDE2195	3.741e-58	205.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR34280931_k127_1005248_65	330214.NIDE2194	3.842e-189	595.0	COG1533@1|root,COG1533@2|Bacteria,3J0QV@40117|Nitrospirae	40117|Nitrospirae	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR34280931_k127_1005248_39	330214.NIDE2193	7.552e-252	784.0	COG0172@1|root,COG0172@2|Bacteria,3J0EP@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR34280931_k127_1005248_84	330214.NIDE0584	1.381e-161	542.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE8,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR34280931_k127_1005248_227	1479235.KK366039_gene1789	0.00085	45.0	COG2963@1|root,COG2963@2|Bacteria,1RIQ6@1224|Proteobacteria,1SDSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153,HTH_Tnp_1
SRR34280931_k127_1005248_205	243164.DET0166	1.133e-12	69.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi,34DDP@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_1005248_228	392499.Swit_3384	0.0009325	46.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR34280931_k127_1005248_100	330214.NIDE1789	1.19e-131	423.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096,Recombinase,Resolvase,Zn_ribbon_recom
SRR34280931_k127_1005248_151	929562.Emtol_3930	2.017e-58	212.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47UDR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_1005248_104	96561.Dole_3113	1.243e-117	400.0	COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR34280931_k127_1005248_7	330214.NIDE2030	0.0	1422.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
SRR34280931_k127_1005248_30	330214.NIDE2029	8.95e-290	910.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,DUF11,HemolysinCabind,PT-VENN
SRR34280931_k127_1005248_18	330214.NIDE2028	0.0	1089.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,POTRA_2,ShlB
SRR34280931_k127_1005248_78	330214.NIDE2027	2.429e-178	563.0	COG3409@1|root,COG3409@2|Bacteria,3J1B1@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SRR34280931_k127_1005248_76	330214.NIDE2026	2.362e-180	569.0	COG3018@1|root,COG3018@2|Bacteria,3J1BT@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_10	330214.NIDE2025	0.0	1364.0	COG0515@1|root,COG1196@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1196@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K03615,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Complex1_51K,DUF5067,P22_portal,RnfC_N,SLBB
SRR34280931_k127_1005248_29	330214.NIDE2024	7.332e-293	902.0	COG0741@1|root,COG1716@1|root,COG0741@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase,SH3_3,SLH,SLT
SRR34280931_k127_1005248_92	330214.NIDE2023	1.009e-148	472.0	2C6PZ@1|root,32V0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_22	330214.NIDE2022	1.013e-318	981.0	COG0515@1|root,COG0515@2|Bacteria	330214.NIDE2022|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_37	330214.NIDE2021	3.011e-260	806.0	COG0642@1|root,COG2205@2|Bacteria	330214.NIDE2021|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1005248_32	330214.NIDE2020	6.043e-273	843.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1005248_124	96561.Dole_2899	4.856e-86	303.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
SRR34280931_k127_1005248_170	768670.Calni_0858	2.261e-41	164.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CarbopepD_reg_2,DUF4384,NPCBM,Plug,SBBP
SRR34280931_k127_1005248_201	1029823.AFIE01000014_gene2988	1.41e-20	94.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria,3NN5I@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
SRR34280931_k127_1005248_132	330214.NIDE1997	1.046e-78	274.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
SRR34280931_k127_1005248_130	420324.KI912033_gene2604	5.863e-81	276.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2VF51@28211|Alphaproteobacteria,1JXCN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve
SRR34280931_k127_1005248_196	981336.F944_02913	6.114e-23	102.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,1RW9F@1236|Gammaproteobacteria,3NJTA@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,rve,rve_3
SRR34280931_k127_1005248_211	330214.NIDE3762	1.854e-08	61.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_1049189_2	330214.NIDE2031	1.714e-90	300.0	COG1980@1|root,COG1980@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
SRR34280931_k127_1049189_0	1162668.LFE_1152	7.106e-237	743.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_1049189_1	1232410.KI421418_gene2231	1.332e-106	364.0	COG2982@1|root,COG2982@2|Bacteria,1PJZH@1224|Proteobacteria,42XG1@68525|delta/epsilon subdivisions,2WTDH@28221|Deltaproteobacteria,43T1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
SRR34280931_k127_1049189_3	330214.NIDE1937	9.727e-23	96.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SRR34280931_k127_1060990_1	330214.NIDE3296	0.0	1263.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR34280931_k127_1060990_5	330214.NIDE3295	1.074e-276	852.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixO
SRR34280931_k127_1060990_8	330214.NIDE3294	4.43e-233	721.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR34280931_k127_1060990_2	330214.NIDE3293	0.0	1227.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,DHOR,DUF3365,FixO,PSCyt1
SRR34280931_k127_1060990_15	330214.NIDE3292	1.066e-80	274.0	COG0746@1|root,COG0746@2|Bacteria,3J1C5@40117|Nitrospirae	40117|Nitrospirae	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR34280931_k127_1060990_14	330214.NIDE3291	3.439e-113	376.0	COG0859@1|root,COG0859@2|Bacteria,3J1E5@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR34280931_k127_1060990_4	330214.NIDE3290	0.0	1013.0	COG0018@1|root,COG0018@2|Bacteria,3J0A8@40117|Nitrospirae	40117|Nitrospirae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR34280931_k127_1060990_7	330214.NIDE3289	1.109e-239	743.0	COG0343@1|root,COG0343@2|Bacteria,3J0DU@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR34280931_k127_1060990_16	330214.NIDE3288	2.156e-57	201.0	COG1862@1|root,COG1862@2|Bacteria,3J0UB@40117|Nitrospirae	40117|Nitrospirae	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR34280931_k127_1060990_3	330214.NIDE3287	0.0	1034.0	COG0342@1|root,COG0342@2|Bacteria,3J09Z@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR34280931_k127_1060990_12	330214.NIDE3286	1.784e-171	541.0	COG0341@1|root,COG0341@2|Bacteria,3J0GM@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR34280931_k127_1060990_0	330214.NIDE3284	0.0	1941.0	COG3829@1|root,COG4191@1|root,COG5000@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,3J117@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_4
SRR34280931_k127_1060990_6	330214.NIDE3283	2.474e-262	814.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1060990_9	330214.NIDE3282	6.635e-230	715.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR34280931_k127_1060990_10	330214.NIDE3281	7.225e-230	711.0	2AKTZ@1|root,31BM1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1060990_13	330214.NIDE3280	6.722e-117	377.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	napG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
SRR34280931_k127_1060990_11	330214.NIDE3279	2.189e-210	656.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR34280931_k127_1060990_17	330214.NIDE3278	2.632e-07	52.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SRR34280931_k127_1075899_2	1123242.JH636435_gene941	1.869e-75	260.0	COG4149@1|root,COG4149@2|Bacteria,2J01Z@203682|Planctomycetes	203682|Planctomycetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR34280931_k127_1075899_0	330214.NIDE3148	2.94e-184	581.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	modC	-	2.10.1.1,3.6.3.29,3.6.3.55	ko:K02017,ko:K02018,ko:K03750,ko:K15497	ko00790,ko01100,ko02010,map00790,map01100,map02010	M00189,M00423	R09735,R10531	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR34280931_k127_1075899_1	661478.OP10G_2396	1.568e-95	332.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR34280931_k127_1107370_16	330214.NIDE2831	1.16e-262	811.0	COG0677@1|root,COG0677@2|Bacteria,3J0HI@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR34280931_k127_1107370_6	330214.NIDE2830	0.0	1322.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
SRR34280931_k127_1107370_49	330214.NIDE2829	4.119e-98	325.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR34280931_k127_1107370_62	269799.Gmet_1857	1.193e-33	134.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42ZXF@68525|delta/epsilon subdivisions,2WV6V@28221|Deltaproteobacteria,43UYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:N_methyl_2	oxpG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR34280931_k127_1107370_55	330214.NIDE2827	2.729e-80	278.0	COG1388@1|root,COG3170@1|root,COG1388@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR34280931_k127_1107370_18	330214.NIDE2826	7.7e-238	738.0	COG1459@1|root,COG1459@2|Bacteria,3J0HZ@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SRR34280931_k127_1107370_9	330214.NIDE2825	0.0	1111.0	COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	2|Bacteria	NU	Type II/IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR34280931_k127_1107370_25	330214.NIDE2824	8.74e-194	606.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR34280931_k127_1107370_43	330214.NIDE2823	5.545e-113	366.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02461,ko:K02662,ko:K02663,ko:K12289	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilN
SRR34280931_k127_1107370_45	330214.NIDE2820	3.741e-110	359.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	tklG	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	-
SRR34280931_k127_1107370_17	330214.NIDE2819	1.045e-248	772.0	COG0014@1|root,COG0014@2|Bacteria,3J0ET@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR34280931_k127_1107370_13	330214.NIDE2818	1.731e-295	915.0	2F0JI@1|root,33TN8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1107370_56	330214.NIDE2817	1.431e-70	244.0	COG4968@1|root,COG4968@2|Bacteria,3J14E@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSG
SRR34280931_k127_1107370_23	330214.NIDE2816	1.487e-203	639.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,3J0NC@40117|Nitrospirae	40117|Nitrospirae	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR34280931_k127_1107370_21	330214.NIDE2815	4.427e-219	686.0	COG3664@1|root,COG3664@2|Bacteria	2|Bacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39,RicinB_lectin_2,Ricin_B_lectin
SRR34280931_k127_1107370_69	395493.BegalDRAFT_1086	3.223e-13	70.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales	72273|Thiotrichales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR34280931_k127_1107370_61	379066.GAU_2903	4.245e-36	139.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR34280931_k127_1107370_66	518766.Rmar_2454	1.52e-14	75.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FIZ6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR34280931_k127_1107370_50	1268635.Loa_01295	2.306e-95	329.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1JCMG@118969|Legionellales	118969|Legionellales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR34280931_k127_1107370_44	272624.lpg1095	5.297e-111	372.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1JE1A@118969|Legionellales	118969|Legionellales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
SRR34280931_k127_1107370_3	1122165.AUHS01000012_gene2815	0.0	1506.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1JDFS@118969|Legionellales	118969|Legionellales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SRR34280931_k127_1107370_63	596154.Alide2_1831	1.57e-30	127.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,4AEQ3@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR34280931_k127_1107370_42	909663.KI867150_gene2709	4.261e-115	376.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42R4P@68525|delta/epsilon subdivisions,2X5AT@28221|Deltaproteobacteria,2MQF9@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR34280931_k127_1107370_34	909663.KI867150_gene2708	3.95e-143	466.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42T20@68525|delta/epsilon subdivisions,2WP7S@28221|Deltaproteobacteria,2MQGC@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Integrase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR34280931_k127_1107370_73	1297569.MESS2_1650005	1.773e-08	60.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
SRR34280931_k127_1107370_75	535289.Dtpsy_2169	6.729e-05	48.0	COG2963@1|root,COG2963@2|Bacteria,1N2T5@1224|Proteobacteria,2WENN@28216|Betaproteobacteria,4AFZ1@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Transposase IS3	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_1107370_14	330214.NIDE1952	4.735e-276	876.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
SRR34280931_k127_1107370_10	330214.NIDE1953	0.0	1065.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,POTRA_2,ShlB
SRR34280931_k127_1107370_39	330214.NIDE1954	3.369e-126	409.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SRR34280931_k127_1107370_4	330214.NIDE1955	0.0	1459.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
SRR34280931_k127_1107370_29	330214.NIDE1956	1.521e-173	547.0	COG3409@1|root,COG3409@2|Bacteria,3J1B1@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SRR34280931_k127_1107370_28	330214.NIDE1957	1.387e-176	557.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc,Yop-YscD_cpl
SRR34280931_k127_1107370_36	330214.NIDE1958	5.698e-137	438.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR34280931_k127_1107370_22	330214.NIDE1959	3.482e-208	649.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
SRR34280931_k127_1107370_40	330214.NIDE1960	4.314e-119	385.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR,VIT,VWA_3
SRR34280931_k127_1107370_2	330214.NIDE1961	0.0	1707.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3J14G@40117|Nitrospirae	40117|Nitrospirae	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR34280931_k127_1107370_11	330214.NIDE1962	0.0	1063.0	COG0457@1|root,COG0457@2|Bacteria,3J1AF@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_16
SRR34280931_k127_1107370_24	330214.NIDE1969	2.068e-200	631.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria	2|Bacteria	T	FHA domain	impI	-	2.7.11.1	ko:K07169,ko:K08884,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	3.A.23.1	-	-	FHA
SRR34280931_k127_1107370_54	330214.NIDE1970	1.495e-87	293.0	COG3521@1|root,COG3521@2|Bacteria	2|Bacteria	D	Type VI secretion	lip1	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
SRR34280931_k127_1107370_15	330214.NIDE1971	9.87e-275	847.0	COG3522@1|root,COG3522@2|Bacteria,3J17B@40117|Nitrospirae	40117|Nitrospirae	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR34280931_k127_1107370_37	330214.NIDE1972	1.933e-136	435.0	COG3455@1|root,COG3455@2|Bacteria	2|Bacteria	S	Type VI secretion system protein DotU	dotU1	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
SRR34280931_k127_1107370_0	330214.NIDE1973	0.0	2339.0	COG3523@1|root,COG3523@2|Bacteria,3J159@40117|Nitrospirae	40117|Nitrospirae	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
SRR34280931_k127_1107370_27	330214.NIDE1974	4.394e-181	569.0	COG3913@1|root,COG3913@2|Bacteria	2|Bacteria	T	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890,ko:K11910	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2094
SRR34280931_k127_1107370_30	330214.NIDE1975	2.451e-162	513.0	COG4455@1|root,COG4455@2|Bacteria	2|Bacteria	U	Protein of avirulence locus involved in temperature-dependent protein secretion	impE	-	-	ko:K03217,ko:K11898	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	ImpE,TPR_19
SRR34280931_k127_1107370_19	330214.NIDE1976	3.998e-228	708.0	COG3515@1|root,COG3515@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	impA	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
SRR34280931_k127_1107370_48	330214.NIDE1977	3.713e-102	334.0	COG3516@1|root,COG3516@2|Bacteria,3J1B6@40117|Nitrospirae	40117|Nitrospirae	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
SRR34280931_k127_1107370_12	330214.NIDE1978	6.4e-323	989.0	COG3517@1|root,COG3517@2|Bacteria,3J0Z9@40117|Nitrospirae	40117|Nitrospirae	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
SRR34280931_k127_1107370_52	330214.NIDE1979	3.589e-89	294.0	COG3157@1|root,COG3157@2|Bacteria	2|Bacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR34280931_k127_1107370_77	1242864.D187_009835	0.0001791	51.0	28MP9@1|root,2ZAYN@2|Bacteria,1NR2W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1107370_33	330214.NIDE1982	1.432e-148	474.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	impF	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
SRR34280931_k127_1107370_7	330214.NIDE1983	0.0	1211.0	COG3519@1|root,COG3519@2|Bacteria,3J114@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:T6SS_VipB	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
SRR34280931_k127_1107370_51	886293.Sinac_2406	1.099e-89	308.0	COG3520@1|root,COG3520@2|Bacteria,2IZ33@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SRR34280931_k127_1107370_1	330214.NIDE1985	0.0	1743.0	COG0542@1|root,COG0542@2|Bacteria,3J0W0@40117|Nitrospirae	40117|Nitrospirae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
SRR34280931_k127_1107370_76	330214.NIDE3523	0.0001028	45.0	COG5266@1|root,COG5266@2|Bacteria	2|Bacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
SRR34280931_k127_1107370_5	330214.NIDE1987	0.0	1361.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,3J13S@40117|Nitrospirae	40117|Nitrospirae	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
SRR34280931_k127_1107370_64	330214.NIDE1988	6.284e-29	122.0	2CMCS@1|root,32SEB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1107370_32	314278.NB231_12129	8.4e-149	479.0	COG5351@1|root,COG5351@2|Bacteria,1R3ZF@1224|Proteobacteria,1S0MS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169
SRR34280931_k127_1107370_31	1116472.MGMO_120c00290	6.641e-151	484.0	COG0304@1|root,COG0304@2|Bacteria,1R618@1224|Proteobacteria,1S1M0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	synthase	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR34280931_k127_1107370_57	314278.NB231_12139	7.72e-63	226.0	COG1475@1|root,COG1475@2|Bacteria,1RIT4@1224|Proteobacteria,1SZ3U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	GHH signature containing HNH/Endo VII superfamily nuclease toxin  2	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,Tox-GHH2
SRR34280931_k127_1107370_78	945550.VISI1226_03970	0.0002925	52.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1XV5E@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
SRR34280931_k127_1107370_70	1347086.CCBA010000022_gene2816	3.508e-12	73.0	2E9KM@1|root,333TD@2|Bacteria,1VW4V@1239|Firmicutes,4HWQP@91061|Bacilli,1ZGRR@1386|Bacillus	91061|Bacilli	S	Immunity protein 26	-	-	-	-	-	-	-	-	-	-	-	-	Imm26
SRR34280931_k127_1107370_72	1173263.Syn7502_00712	2.046e-09	64.0	2BR4H@1|root,32K2F@2|Bacteria,1GGVQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
SRR34280931_k127_1107370_20	330214.NIDE2002	1.21e-220	689.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR34280931_k127_1107370_68	909663.KI867150_gene499	2.844e-13	74.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,438DV@68525|delta/epsilon subdivisions,2WXRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR34280931_k127_1107370_59	330214.NIDE2003	4.945e-48	172.0	COG4115@1|root,COG4115@2|Bacteria	2|Bacteria	D	mRNA cleavage	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
SRR34280931_k127_1107370_60	330214.NIDE2004	1.098e-42	157.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
SRR34280931_k127_1107370_35	330214.NIDE2005	1.226e-141	451.0	2C0V6@1|root,33MXI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1107370_47	330214.NIDE2006	1.312e-102	335.0	2DCV2@1|root,2ZFFG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_188	338966.Ppro_1126	2.963e-33	144.0	COG4974@1|root,COG4974@2|Bacteria,1QV9T@1224|Proteobacteria,43CGV@68525|delta/epsilon subdivisions,2X7S1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_1110403_23	330214.NIDE4019	4.461e-284	876.0	COG0008@1|root,COG0008@2|Bacteria,3J0CJ@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR34280931_k127_1110403_92	330214.NIDE4021	4.689e-125	402.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	poxF	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR34280931_k127_1110403_127	330214.NIDE4022	1.835e-83	277.0	COG0633@1|root,COG0633@2|Bacteria,3J1AM@40117|Nitrospirae	40117|Nitrospirae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
SRR34280931_k127_1110403_117	330214.NIDE4023	1.213e-98	322.0	COG1959@1|root,COG1959@2|Bacteria,3J18M@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR34280931_k127_1110403_35	330214.NIDE4024	4.485e-258	797.0	COG1104@1|root,COG1104@2|Bacteria,3J0AX@40117|Nitrospirae	40117|Nitrospirae	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR34280931_k127_1110403_136	330214.NIDE4025	7.416e-77	258.0	COG0822@1|root,COG0822@2|Bacteria,3J123@40117|Nitrospirae	40117|Nitrospirae	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR34280931_k127_1110403_146	330214.NIDE4026	1.023e-69	237.0	COG0316@1|root,COG0316@2|Bacteria,3J17Y@40117|Nitrospirae	40117|Nitrospirae	S	Iron-sulphur cluster biosynthesis	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR34280931_k127_1110403_112	330214.NIDE4027	8.239e-101	334.0	COG1076@1|root,COG1076@2|Bacteria,3J1CS@40117|Nitrospirae	40117|Nitrospirae	O	DnaJ molecular chaperone homology domain	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	-
SRR34280931_k127_1110403_11	330214.NIDE4028	0.0	1099.0	COG0443@1|root,COG0443@2|Bacteria,3J0YD@40117|Nitrospirae	40117|Nitrospirae	O	Hsp70 protein	hscA	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
SRR34280931_k127_1110403_185	330214.NIDE4029	2.442e-35	135.0	COG2975@1|root,COG2975@2|Bacteria,3J1CR@40117|Nitrospirae	40117|Nitrospirae	S	Iron-sulphur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
SRR34280931_k127_1110403_4	330214.NIDE4030	0.0	1524.0	COG5009@1|root,COG5009@2|Bacteria,3J0BH@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding protein OB-like domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
SRR34280931_k127_1110403_9	330214.NIDE4031	0.0	1204.0	COG1217@1|root,COG1217@2|Bacteria,3J10A@40117|Nitrospirae	40117|Nitrospirae	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU
SRR34280931_k127_1110403_116	330214.NIDE4033	6.771e-99	323.0	COG1225@1|root,COG1225@2|Bacteria,3J12D@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR34280931_k127_1110403_150	330214.NIDE4034	6.139e-66	226.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
SRR34280931_k127_1110403_85	330214.NIDE4035	1.756e-132	430.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_1110403_96	330214.NIDE4036	4.153e-124	401.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
SRR34280931_k127_1110403_50	330214.NIDE4037	5.584e-210	658.0	COG1511@1|root,COG1511@2|Bacteria	2|Bacteria	Q	domain protein	-	-	-	ko:K02004,ko:K06994	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_1110403_72	330214.NIDE4038	9.575e-151	477.0	COG0720@1|root,COG0720@2|Bacteria,3J0TW@40117|Nitrospirae	40117|Nitrospirae	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR34280931_k127_1110403_119	330214.NIDE4039	3.761e-95	318.0	COG0247@1|root,COG0247@2|Bacteria,3J187@40117|Nitrospirae	40117|Nitrospirae	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
SRR34280931_k127_1110403_38	330214.NIDE4040	5.565e-249	773.0	COG0247@1|root,COG1146@1|root,COG0247@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3,1.2.7.3	ko:K00113,ko:K00176,ko:K05524,ko:K13795,ko:K13796	ko00020,ko00564,ko00720,ko01100,ko01110,ko01120,ko01200,map00020,map00564,map00720,map01100,map01110,map01120,map01200	M00009,M00011,M00173,M00620	R00848,R01197	RC00004,RC00029,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,DUF3470,DUF3501,Fer4,Fer4_8
SRR34280931_k127_1110403_123	330214.NIDE4041	1.114e-88	294.0	COG1592@1|root,COG1592@2|Bacteria,3J0RY@40117|Nitrospirae	40117|Nitrospirae	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR34280931_k127_1110403_142	330214.NIDE4042	6.315e-72	246.0	COG0735@1|root,COG0735@2|Bacteria,3J1CV@40117|Nitrospirae	40117|Nitrospirae	L	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR34280931_k127_1110403_103	330214.NIDE4043	3.759e-111	362.0	COG1898@1|root,COG1898@2|Bacteria,3J0K0@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR34280931_k127_1110403_165	330214.NIDE4045	1.382e-49	177.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_1110403_164	330214.NIDE4047	4.591e-51	184.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR34280931_k127_1110403_104	330214.NIDE4049	8.924e-111	359.0	2BXN6@1|root,2ZK04@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_125	330214.NIDE4050	1.008e-87	296.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR34280931_k127_1110403_195	1217708.F887_00441	1.149e-27	121.0	290UI@1|root,2ZNGI@2|Bacteria,1QSJH@1224|Proteobacteria,1RW1K@1236|Gammaproteobacteria,3NK0J@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_132	330214.NIDE4057	1.75e-79	267.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
SRR34280931_k127_1110403_51	330214.NIDE4060	3.465e-208	651.0	COG1858@1|root,COG1858@2|Bacteria,3J0GH@40117|Nitrospirae	40117|Nitrospirae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR34280931_k127_1110403_111	330214.NIDE4061	2.166e-101	338.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR34280931_k127_1110403_21	330214.NIDE4062	7.544e-290	894.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pcd	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR34280931_k127_1110403_49	330214.NIDE4063	1.476e-211	659.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
SRR34280931_k127_1110403_78	330214.NIDE4064	1.726e-140	449.0	COG1774@1|root,COG1774@2|Bacteria,3J0MI@40117|Nitrospirae	40117|Nitrospirae	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR34280931_k127_1110403_166	330214.NIDE4065	1.557e-49	176.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR34280931_k127_1110403_126	330214.NIDE4066	2.672e-85	284.0	COG2947@1|root,COG2947@2|Bacteria	2|Bacteria	L	Ubiquinol--cytochrome c reductase	MA20_25125	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR34280931_k127_1110403_90	330214.NIDE4067	1.601e-128	416.0	COG1434@1|root,COG1434@2|Bacteria,3J1BM@40117|Nitrospirae	40117|Nitrospirae	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR34280931_k127_1110403_94	330214.NIDE4069	9.878e-125	405.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR34280931_k127_1110403_95	330214.NIDE4070	1.04e-124	401.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
SRR34280931_k127_1110403_15	330214.NIDE4071	0.0	1031.0	COG0514@1|root,COG0514@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase (RecQ)	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR34280931_k127_1110403_12	330214.NIDE4073	0.0	1074.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	VPA1441	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,FG-GAP_2,OprD,Porin_4
SRR34280931_k127_1110403_160	330214.NIDE4074	4.447e-54	191.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR34280931_k127_1110403_171	330214.NIDE4075	2.696e-45	165.0	COG1826@1|root,COG1826@2|Bacteria,3J1A4@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR34280931_k127_1110403_22	330214.NIDE4076	4.198e-286	882.0	COG1565@1|root,COG1565@2|Bacteria	2|Bacteria	P	acr, cog1565	truB	-	1.9.3.1,2.7.7.13,3.2.1.97,5.4.99.25	ko:K00412,ko:K00971,ko:K02275,ko:K02389,ko:K03177,ko:K17624	ko00051,ko00190,ko00520,ko01100,ko01110,ko02020,ko02040,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00051,map00190,map00520,map01100,map01110,map02020,map02040,map04260,map04714,map04932,map05010,map05012,map05016	M00114,M00151,M00152,M00155,M00361,M00362	R00081,R00885	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000,ko02035,ko03016,ko03029	3.D.4.2,3.D.4.4,3.D.4.6	GH101	-	Methyltransf_28
SRR34280931_k127_1110403_114	330214.NIDE4077	2.557e-100	331.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE4077|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_18	330214.NIDE4079	5.446e-316	972.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_1110403_70	330214.NIDE4080	4.214e-154	488.0	COG0463@1|root,COG0463@2|Bacteria,3J13C@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_1110403_192	1367847.JCM7686_3259	5.189e-29	122.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria,2PXWX@265|Paracoccus	28211|Alphaproteobacteria	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
SRR34280931_k127_1110403_13	330214.NIDE4082	0.0	1046.0	COG1807@1|root,COG1807@2|Bacteria,3J12H@40117|Nitrospirae	40117|Nitrospirae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_71	330214.NIDE4083	6.577e-152	490.0	COG0671@1|root,COG0671@2|Bacteria,3J1CX@40117|Nitrospirae	40117|Nitrospirae	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR34280931_k127_1110403_105	404589.Anae109_2847	2.583e-109	365.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR34280931_k127_1110403_10	330214.NIDE4085	0.0	1126.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PDZ_2,Peptidase_M1,Peptidase_M28
SRR34280931_k127_1110403_83	330214.NIDE4086	7.979e-138	442.0	COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_1110403_63	330214.NIDE4087	2.467e-173	546.0	COG0552@1|root,COG0552@2|Bacteria,3J0GY@40117|Nitrospirae	40117|Nitrospirae	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR34280931_k127_1110403_147	330214.NIDE4088	2.015e-69	239.0	COG0319@1|root,COG0319@2|Bacteria,3J0US@40117|Nitrospirae	40117|Nitrospirae	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR34280931_k127_1110403_53	330214.NIDE4089	8.561e-205	640.0	COG1702@1|root,COG1702@2|Bacteria,3J0AD@40117|Nitrospirae	40117|Nitrospirae	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR34280931_k127_1110403_68	330214.NIDE4090	5.022e-155	497.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,RHS_repeat,SprB
SRR34280931_k127_1110403_0	330214.NIDE4091	0.0	2624.0	COG3419@1|root,COG3419@2|Bacteria,3J100@40117|Nitrospirae	40117|Nitrospirae	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
SRR34280931_k127_1110403_56	330214.NIDE4094	1.08e-193	608.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
SRR34280931_k127_1110403_131	330214.NIDE4095	3.964e-80	269.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	ppdC	-	-	ko:K02671,ko:K02681,ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	N_methyl,T2SSppdC
SRR34280931_k127_1110403_143	330214.NIDE4096	1.479e-71	244.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	GspH,N_methyl
SRR34280931_k127_1110403_19	330214.NIDE4097	1.958e-312	965.0	COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR34280931_k127_1110403_33	330214.NIDE4098	1.052e-262	815.0	COG3217@1|root,COG4726@1|root,COG3217@2|Bacteria,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	DUF3494,MOSC_N
SRR34280931_k127_1110403_118	330214.NIDE4099	2.32e-98	331.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
SRR34280931_k127_1110403_140	330214.NIDE4100	1.178e-72	250.0	COG4940@1|root,COG4940@2|Bacteria	2|Bacteria	U	Putative Competence protein ComGF	comGF	-	-	ko:K02246,ko:K02248	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComGF,N_methyl
SRR34280931_k127_1110403_155	330214.NIDE4101	1.175e-58	209.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	VP0657	-	-	ko:K02457,ko:K02672,ko:K08084,ko:K08085	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl,PilS
SRR34280931_k127_1110403_75	330214.NIDE4102	2.464e-146	466.0	COG1989@1|root,COG1989@2|Bacteria,3J0SK@40117|Nitrospirae	40117|Nitrospirae	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR34280931_k127_1110403_182	330214.NIDE4103	1.429e-40	154.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Response_reg
SRR34280931_k127_1110403_87	330214.NIDE4104	2.213e-130	419.0	COG0566@1|root,COG0566@2|Bacteria,3J0RH@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR34280931_k127_1110403_26	330214.NIDE4105	4.017e-282	870.0	COG0215@1|root,COG0215@2|Bacteria,3J0CM@40117|Nitrospirae	40117|Nitrospirae	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR34280931_k127_1110403_89	330214.NIDE4106	6.944e-129	412.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR34280931_k127_1110403_73	330214.NIDE4107	1.066e-150	481.0	COG0496@1|root,COG0496@2|Bacteria,3J0IG@40117|Nitrospirae	40117|Nitrospirae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR34280931_k127_1110403_149	330214.NIDE4108	5.125e-66	226.0	COG0789@1|root,COG0789@2|Bacteria,3J0VF@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR34280931_k127_1110403_163	330214.NIDE4109	3.692e-51	182.0	COG0776@1|root,COG0776@2|Bacteria,3J1CY@40117|Nitrospirae	40117|Nitrospirae	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR34280931_k127_1110403_16	330214.NIDE4110	0.0	1024.0	COG0119@1|root,COG0119@2|Bacteria,3J0DC@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR34280931_k127_1110403_39	330214.NIDE4111	3.513e-244	758.0	COG0527@1|root,COG0527@2|Bacteria,3J0AZ@40117|Nitrospirae	40117|Nitrospirae	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR34280931_k127_1110403_42	330214.NIDE4112	3.694e-235	731.0	COG3635@1|root,COG3635@2|Bacteria,3J0YA@40117|Nitrospirae	40117|Nitrospirae	G	Metalloenzyme superfamily	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR34280931_k127_1110403_47	330214.NIDE4113	1.371e-215	670.0	COG0498@1|root,COG0498@2|Bacteria,3J0FI@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC2	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_1110403_30	330214.NIDE4114	6.853e-265	818.0	COG0440@1|root,COG0460@1|root,COG0440@2|Bacteria,COG0460@2|Bacteria,3J0G1@40117|Nitrospirae	40117|Nitrospirae	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR34280931_k127_1110403_32	330214.NIDE4115	4.891e-263	810.0	COG0436@1|root,COG0436@2|Bacteria,3J0ED@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_1110403_77	330214.NIDE4117	2.085e-141	451.0	COG0854@1|root,COG0854@2|Bacteria,3J0KZ@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRR34280931_k127_1110403_29	330214.NIDE4119	1.443e-276	857.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3J0J1@40117|Nitrospirae	40117|Nitrospirae	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	-	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR34280931_k127_1110403_137	330214.NIDE4120	1.461e-76	261.0	COG0802@1|root,COG0802@2|Bacteria,3J1AZ@40117|Nitrospirae	40117|Nitrospirae	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR34280931_k127_1110403_5	330214.NIDE4122	0.0	1483.0	COG0249@1|root,COG0249@2|Bacteria,3J0CE@40117|Nitrospirae	40117|Nitrospirae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR34280931_k127_1110403_37	330214.NIDE4126	3.969e-250	774.0	COG0612@1|root,COG0612@2|Bacteria,3J0GS@40117|Nitrospirae	40117|Nitrospirae	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR34280931_k127_1110403_7	330214.NIDE4127	0.0	1322.0	COG1185@1|root,COG1185@2|Bacteria,3J0DX@40117|Nitrospirae	40117|Nitrospirae	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR34280931_k127_1110403_168	330214.NIDE4129	1.009e-46	168.0	COG0184@1|root,COG0184@2|Bacteria,3J0RA@40117|Nitrospirae	40117|Nitrospirae	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR34280931_k127_1110403_65	330214.NIDE4130	8.165e-167	529.0	COG0130@1|root,COG0130@2|Bacteria,3J0KH@40117|Nitrospirae	40117|Nitrospirae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
SRR34280931_k127_1110403_145	330214.NIDE4131	8.065e-70	237.0	COG0858@1|root,COG0858@2|Bacteria,3J0VV@40117|Nitrospirae	40117|Nitrospirae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR34280931_k127_1110403_172	330214.NIDE4132	8.079e-45	165.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR34280931_k127_1110403_43	289376.THEYE_A1884	2.233e-234	752.0	COG0532@1|root,COG0532@2|Bacteria,3J0CC@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR34280931_k127_1110403_44	330214.NIDE4134	3.194e-226	703.0	COG0195@1|root,COG0195@2|Bacteria,3J0DF@40117|Nitrospirae	40117|Nitrospirae	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR34280931_k127_1110403_128	330214.NIDE4135	2.49e-83	280.0	COG0779@1|root,COG0779@2|Bacteria,3J0UD@40117|Nitrospirae	40117|Nitrospirae	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR34280931_k127_1110403_76	330214.NIDE4136	1.445e-143	460.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	dat	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
SRR34280931_k127_1110403_151	330214.NIDE4138	9.89e-66	224.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR34280931_k127_1110403_124	330214.NIDE4139	1.328e-88	294.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR34280931_k127_1110403_139	330214.NIDE4140	3.39e-74	249.0	COG1145@1|root,COG1145@2|Bacteria,3J1BF@40117|Nitrospirae	40117|Nitrospirae	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_20	330214.NIDE4143	2.25e-304	938.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Spermine_synth
SRR34280931_k127_1110403_144	330214.NIDE4144	6.055e-71	241.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	opuCA	-	2.7.7.7	ko:K02342,ko:K05847,ko:K07182	ko00230,ko00240,ko01100,ko02010,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02010,map03030,map03430,map03440	M00209,M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02000,ko03032,ko03400	3.A.1.12	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR34280931_k127_1110403_24	330214.NIDE4145	3.85e-283	871.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR34280931_k127_1110403_81	330214.NIDE4146	3.409e-139	443.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1110403_193	877455.Metbo_1657	9.578e-29	127.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1110403_52	330214.NIDE4148	2.376e-207	648.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1110403_54	330214.NIDE4149	1.476e-198	623.0	COG1413@1|root,COG1413@2|Bacteria,3J1E2@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1110403_27	330214.NIDE4150	3.081e-281	866.0	COG1413@1|root,COG1413@2|Bacteria,3J1E2@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1110403_58	330214.NIDE4152	6.316e-190	597.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR34280931_k127_1110403_36	330214.NIDE4155	2.447e-257	795.0	293H1@1|root,2ZQZ6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_212	1198114.AciX9_1310	1.79e-06	59.0	COG4914@1|root,COG4914@2|Bacteria,3Y9D7@57723|Acidobacteria,2JNAR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_203	1232410.KI421424_gene1830	9.274e-15	84.0	2BIZB@1|root,32D7T@2|Bacteria,1Q9TV@1224|Proteobacteria,431GP@68525|delta/epsilon subdivisions,2WWKI@28221|Deltaproteobacteria,43VCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR34280931_k127_1110403_152	330214.NIDE4157	3.639e-65	225.0	COG3824@1|root,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR34280931_k127_1110403_2	330214.NIDE4158	0.0	1663.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3J0DP@40117|Nitrospirae	40117|Nitrospirae	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR34280931_k127_1110403_135	330214.NIDE4159	1.104e-77	261.0	2E4SV@1|root,32ZM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR34280931_k127_1110403_130	330214.NIDE4161	1.763e-80	269.0	COG2210@1|root,COG2210@2|Bacteria	2|Bacteria	P	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR34280931_k127_1110403_86	330214.NIDE4162	6.138e-131	420.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2,4.2.99.18	ko:K01142,ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR34280931_k127_1110403_191	330214.NIDE4163	4.131e-29	116.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR34280931_k127_1110403_34	330214.NIDE4164	1.561e-261	813.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria	2|Bacteria	E	Formiminotransferase domain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR34280931_k127_1110403_177	330214.NIDE4165	1.947e-43	158.0	COG0425@1|root,COG0425@2|Bacteria,3J1C1@40117|Nitrospirae	40117|Nitrospirae	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR34280931_k127_1110403_108	330214.NIDE4166	1.487e-105	343.0	COG2210@1|root,COG2210@2|Bacteria	2|Bacteria	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
SRR34280931_k127_1110403_41	330214.NIDE4167	1.641e-236	732.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR34280931_k127_1110403_8	330214.NIDE4168	0.0	1226.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,3J0Y7@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR34280931_k127_1110403_156	330214.NIDE4169	1.527e-58	207.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.1.3.18,3.1.3.23	ko:K01091,ko:K07025,ko:K19270	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR34280931_k127_1110403_48	330214.NIDE4172	1.767e-214	667.0	COG0451@1|root,COG0451@2|Bacteria,3J0ZC@40117|Nitrospirae	40117|Nitrospirae	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR34280931_k127_1110403_17	330214.NIDE4173	0.0	1022.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR34280931_k127_1110403_133	330214.NIDE4174	1.619e-78	266.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR34280931_k127_1110403_62	330214.NIDE4175	8.874e-176	561.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_1110403_84	330214.NIDE4176	1.886e-137	442.0	COG1587@1|root,COG1587@2|Bacteria	2|Bacteria	H	uroporphyrinogen-III synthase activity	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Trans_reg_C
SRR34280931_k127_1110403_183	272624.lpg0428	1.768e-38	148.0	COG0346@1|root,COG0346@2|Bacteria,1N6M5@1224|Proteobacteria,1SUW4@1236|Gammaproteobacteria,1JEWF@118969|Legionellales	118969|Legionellales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR34280931_k127_1110403_196	933262.AXAM01000063_gene610	5.288e-26	108.0	COG1598@1|root,COG1598@2|Bacteria,1PKQ0@1224|Proteobacteria,438VX@68525|delta/epsilon subdivisions,2X9PU@28221|Deltaproteobacteria,2MPDH@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_194	247490.KSU1_D1022	8.549e-28	114.0	COG1724@1|root,COG1724@2|Bacteria,2J4RJ@203682|Planctomycetes	203682|Planctomycetes	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_59	330214.NIDE4178	4.072e-187	586.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_1110403_102	330214.NIDE4179	7.142e-112	366.0	COG3026@1|root,COG3026@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	DUF4412,FtsX,LolA_like,MucB_RseB,MucB_RseB_C,zf-HC2
SRR34280931_k127_1110403_99	330214.NIDE4180	7.738e-119	384.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	Cj0420	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR34280931_k127_1110403_69	330214.NIDE4181	8.802e-155	494.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	2.7.13.3	ko:K03407,ko:K03832	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	2.C.1.1	-	-	CarbopepD_reg_2,GUN4,Gram_pos_anchor,HAMP,NIT,TonB_2,TonB_C,Trypsin_2
SRR34280931_k127_1110403_46	330214.NIDE4183	7.708e-218	677.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	tdh	-	1.1.1.103,2.7.13.3	ko:K00060,ko:K07777	ko00260,ko02020,map00260,map02020	M00478	R01465	RC00525	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ADH_N,ADH_zinc_N
SRR34280931_k127_1110403_45	330214.NIDE4184	2.595e-220	688.0	COG0156@1|root,COG0156@2|Bacteria,3J0XU@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_1110403_64	330214.NIDE4185	2.198e-169	540.0	COG2853@1|root,COG2853@2|Bacteria	2|Bacteria	M	Lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
SRR34280931_k127_1110403_74	330214.NIDE4187	5.74e-147	467.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR34280931_k127_1110403_199	330214.NIDE1885	2.059e-23	108.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	MtrB_PioB,OMP_b-brl
SRR34280931_k127_1110403_198	697282.Mettu_3255	1.385e-23	103.0	2E7TI@1|root,333ZE@2|Bacteria,1NA5N@1224|Proteobacteria,1SE9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
SRR34280931_k127_1110403_14	330214.NIDE4188	0.0	1046.0	28J7E@1|root,2Z92U@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR34280931_k127_1110403_184	240015.ACP_0636	3.011e-37	147.0	COG0622@1|root,COG0622@2|Bacteria,3Y51P@57723|Acidobacteria,2JJEG@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR34280931_k127_1110403_55	330214.NIDE4192	2.182e-196	617.0	COG4783@1|root,COG4783@2|Bacteria,3J19Q@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR34280931_k127_1110403_80	330214.NIDE4194	3.064e-139	443.0	COG2013@1|root,COG2013@2|Bacteria	2|Bacteria	S	Mitochondrial biogenesis AIM24	WQ51_05710	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR34280931_k127_1110403_66	330214.NIDE4196	1.177e-158	503.0	COG1639@1|root,COG1639@2|Bacteria,3J0NC@40117|Nitrospirae	40117|Nitrospirae	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR34280931_k127_1110403_61	330214.NIDE4197	7.27e-176	569.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
SRR34280931_k127_1110403_217	1107311.Q767_03905	0.0003512	47.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia,2NVED@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
SRR34280931_k127_1110403_190	314278.NB231_07442	1.166e-29	124.0	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_162	1038869.AXAN01000016_gene1416	1.769e-51	191.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,1K33I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
SRR34280931_k127_1110403_138	338966.Ppro_0402	8.117e-76	264.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2WMWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
SRR34280931_k127_1110403_60	338966.Ppro_0403	5.911e-180	578.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2X5NU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
SRR34280931_k127_1110403_179	322710.Avin_44160	6.044e-43	165.0	COG3009@1|root,COG3009@2|Bacteria,1RII3@1224|Proteobacteria,1SC0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
SRR34280931_k127_1110403_170	330214.NIDE4200	1.096e-45	172.0	2DU53@1|root,33NYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_113	330214.NIDE4201	8.558e-101	331.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1110403_6	330214.NIDE4203	0.0	1447.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE4203|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_98	330214.NIDE4204	2.006e-122	400.0	COG3769@1|root,COG3769@2|Bacteria	2|Bacteria	S	mannosylglycerate metabolic process	mpgP	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897	2.4.1.217,3.1.3.70	ko:K05947,ko:K07026	ko00051,map00051	-	R05768,R05790	RC00005,RC00017,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Hydrolase_3
SRR34280931_k127_1110403_82	330214.NIDE4206	2.009e-138	442.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
SRR34280931_k127_1110403_28	330214.NIDE4207	3.39e-280	861.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR34280931_k127_1110403_202	330214.NIDE4216	7.732e-15	80.0	2E2ZP@1|root,33HJP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_187	330214.NIDE4216	2.059e-34	135.0	2E2ZP@1|root,33HJP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_210	500635.MITSMUL_04645	4.235e-08	62.0	2DS41@1|root,33EEK@2|Bacteria,1W0B1@1239|Firmicutes,4H87Z@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_206	1184251.TCELL_0017	6.284e-12	72.0	COG1637@1|root,arCOG01304@2157|Archaea,2XQ7Z@28889|Crenarchaeota	28889|Crenarchaeota	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR34280931_k127_1110403_120	330214.NIDE4226	1.071e-93	313.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	ccrB	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K06400,ko:K14060	-	-	-	-	ko00000	-	-	-	HTH_7,Recombinase,Resolvase,Zn_ribbon_recom
SRR34280931_k127_1110403_216	767817.Desgi_3595	0.0001283	47.0	COG2452@1|root,COG2452@2|Bacteria,1UZS8@1239|Firmicutes,25DRX@186801|Clostridia	186801|Clostridia	L	HTH transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,Resolvase
SRR34280931_k127_1110403_181	439235.Dalk_4586	3.297e-41	164.0	2DXZD@1|root,32V4G@2|Bacteria,1N4N1@1224|Proteobacteria,42UVK@68525|delta/epsilon subdivisions,2WQ0A@28221|Deltaproteobacteria,2MPDG@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_88	330214.NIDE3441	8.936e-130	428.0	COG0305@1|root,COG0305@2|Bacteria,3J0EZ@40117|Nitrospirae	40117|Nitrospirae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR34280931_k127_1110403_40	330214.NIDE4233	3.795e-242	752.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
SRR34280931_k127_1110403_91	330214.NIDE4234	2.563e-126	407.0	COG0284@1|root,COG0284@2|Bacteria,3J0SC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR34280931_k127_1110403_214	1382306.JNIM01000001_gene3758	1.063e-05	51.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR34280931_k127_1110403_57	330214.NIDE4236	1.526e-191	603.0	COG1466@1|root,COG1466@2|Bacteria,3J1EC@40117|Nitrospirae	40117|Nitrospirae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR34280931_k127_1110403_3	330214.NIDE4238	0.0	1596.0	COG0495@1|root,COG0495@2|Bacteria,3J0F8@40117|Nitrospirae	40117|Nitrospirae	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR34280931_k127_1110403_107	330214.NIDE4239	8.043e-106	349.0	COG0500@1|root,COG2226@2|Bacteria,3J1DH@40117|Nitrospirae	40117|Nitrospirae	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1110403_1	330214.NIDE4240	0.0	2104.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_1110403_93	330214.NIDE4241	4.762e-125	403.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR34280931_k127_1110403_25	330214.NIDE4242	6.357e-283	872.0	COG1160@1|root,COG1160@2|Bacteria,3J0G3@40117|Nitrospirae	40117|Nitrospirae	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	engA	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR34280931_k127_1110403_101	330214.NIDE4245	4.565e-116	376.0	COG1595@1|root,COG1595@2|Bacteria,3J1A1@40117|Nitrospirae	40117|Nitrospirae	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_1110403_176	330214.NIDE4246	1.048e-43	171.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR34280931_k127_1110403_161	330214.NIDE4247	4.414e-53	191.0	COG2010@1|root,COG2010@2|Bacteria,3J1AX@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K00406,ko:K12263	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,SirB
SRR34280931_k127_1157797_1	1216932.CM240_2074	4.921e-56	218.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,36EMM@31979|Clostridiaceae	186801|Clostridia	M	sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR34280931_k127_1157797_3	330214.NIDE2713	2.917e-18	87.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_1157797_2	330214.NIDE2121	1.14e-44	164.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_1157797_0	330214.NIDE2843	1.022e-59	210.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_1159256_15	330214.NIDE3773	5.254e-316	974.0	COG1067@1|root,COG1067@2|Bacteria,3J0X2@40117|Nitrospirae	40117|Nitrospirae	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
SRR34280931_k127_1159256_84	330214.NIDE3772	9.935e-101	332.0	COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	raiA	-	-	ko:K03704,ko:K05809	-	-	-	-	ko00000,ko03000,ko03009	-	-	-	CSD,Ribosomal_S30AE
SRR34280931_k127_1159256_36	330214.NIDE3770	4.048e-206	666.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR34280931_k127_1159256_101	330214.NIDE3769	1.623e-80	271.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR34280931_k127_1159256_8	330214.NIDE3768	0.0	1191.0	COG0296@1|root,COG0296@2|Bacteria,3J0Y2@40117|Nitrospirae	40117|Nitrospirae	G	Alpha amylase, catalytic domain	-	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR34280931_k127_1159256_107	330214.NIDE3759	6.683e-62	218.0	COG2153@1|root,COG2153@2|Bacteria	2|Bacteria	K	protein acetylation	-	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_10
SRR34280931_k127_1159256_51	330214.NIDE3757	2.393e-167	529.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_1159256_45	330214.NIDE3756	1.432e-185	587.0	COG0845@1|root,COG0845@2|Bacteria,3J15V@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	HlyD_D23
SRR34280931_k127_1159256_0	330214.NIDE3755	0.0	1830.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR34280931_k127_1159256_4	330214.NIDE3754	0.0	1351.0	COG0474@1|root,COG0474@2|Bacteria,3J0WH@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR34280931_k127_1159256_19	330214.NIDE3753	1.871e-275	853.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_1159256_151	330214.NIDE3752	8.652e-11	64.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR34280931_k127_1159256_148	330214.NIDE3752	6.411e-16	85.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR34280931_k127_1159256_149	330214.NIDE3752	4.158e-12	66.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR34280931_k127_1159256_76	330214.NIDE3749	3.672e-123	403.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3749|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_99	330214.NIDE3747	9.835e-81	270.0	2CIIF@1|root,315FB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_2	330214.NIDE3745	0.0	1443.0	COG0474@1|root,COG0474@2|Bacteria,3J0YX@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR34280931_k127_1159256_62	330214.NIDE3744	3.904e-144	463.0	COG3511@1|root,COG3511@2|Bacteria,3J186@40117|Nitrospirae	40117|Nitrospirae	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR34280931_k127_1159256_10	330214.NIDE3743	0.0	1069.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_1159256_12	330214.NIDE3739	0.0	1015.0	COG0029@1|root,COG0029@2|Bacteria,3J0DI@40117|Nitrospirae	40117|Nitrospirae	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR34280931_k127_1159256_120	338963.Pcar_1321	4.087e-47	177.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,43SJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4124)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
SRR34280931_k127_1159256_58	330214.NIDE3737	1.84e-158	502.0	COG0115@1|root,COG0115@2|Bacteria,3J0BM@40117|Nitrospirae	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	pabC	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR34280931_k127_1159256_28	330214.NIDE3736	1.092e-243	760.0	COG0147@1|root,COG0147@2|Bacteria,3J0FG@40117|Nitrospirae	2|Bacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046820,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR34280931_k127_1159256_118	330214.NIDE3735	2.286e-50	179.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR34280931_k127_1159256_61	330214.NIDE3734	2.158e-148	471.0	COG0356@1|root,COG0356@2|Bacteria,3J0RW@40117|Nitrospirae	40117|Nitrospirae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR34280931_k127_1159256_133	330214.NIDE3733	6.928e-38	143.0	COG0636@1|root,COG0636@2|Bacteria,3J198@40117|Nitrospirae	40117|Nitrospirae	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR34280931_k127_1159256_90	330214.NIDE3732	3.586e-90	298.0	COG0711@1|root,COG0711@2|Bacteria,3J1AE@40117|Nitrospirae	40117|Nitrospirae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR34280931_k127_1159256_67	330214.NIDE3731	1.067e-139	449.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	larE	-	4.99.1.12	ko:K06864,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
SRR34280931_k127_1159256_24	330214.NIDE3730	2.396e-268	832.0	COG0612@1|root,COG0612@2|Bacteria,3J0I5@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR34280931_k127_1159256_20	330214.NIDE3729	9.566e-275	848.0	COG0612@1|root,COG0612@2|Bacteria,3J0BY@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR34280931_k127_1159256_37	330214.NIDE3728	2.552e-204	640.0	COG0820@1|root,COG0820@2|Bacteria,3J0CH@40117|Nitrospirae	40117|Nitrospirae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR34280931_k127_1159256_7	330214.NIDE3727	0.0	1270.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,3J0VD@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_3,TPR_6
SRR34280931_k127_1159256_121	330214.NIDE3725	8.817e-47	173.0	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR34280931_k127_1159256_16	330214.NIDE3723	8.39e-306	941.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,3J0C8@40117|Nitrospirae	40117|Nitrospirae	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR34280931_k127_1159256_56	330214.NIDE3722	1.836e-162	512.0	COG1692@1|root,COG1692@2|Bacteria,3J0JW@40117|Nitrospirae	40117|Nitrospirae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR34280931_k127_1159256_34	330214.NIDE3721	1.347e-217	682.0	COG1570@1|root,COG1570@2|Bacteria,3J0S9@40117|Nitrospirae	40117|Nitrospirae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR34280931_k127_1159256_130	330214.NIDE3720	1.266e-40	151.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR34280931_k127_1159256_70	330214.NIDE3719	1.579e-132	426.0	COG1189@1|root,COG1189@2|Bacteria,3J0MD@40117|Nitrospirae	40117|Nitrospirae	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR34280931_k127_1159256_43	330214.NIDE3718	1.192e-194	608.0	COG0451@1|root,COG0451@2|Bacteria,3J12G@40117|Nitrospirae	40117|Nitrospirae	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR34280931_k127_1159256_111	330214.NIDE3717	1.14e-58	204.0	COG0607@1|root,COG0607@2|Bacteria,3J17U@40117|Nitrospirae	40117|Nitrospirae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR34280931_k127_1159256_123	330214.NIDE3715	1.486e-45	166.0	COG1324@1|root,COG1324@2|Bacteria,3J0UM@40117|Nitrospirae	40117|Nitrospirae	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR34280931_k127_1159256_44	330214.NIDE3714	2.374e-193	606.0	COG0739@1|root,COG0739@2|Bacteria,3J0N3@40117|Nitrospirae	40117|Nitrospirae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR34280931_k127_1159256_14	330214.NIDE3713	2.635e-319	984.0	COG2759@1|root,COG2759@2|Bacteria,3J0CI@40117|Nitrospirae	40117|Nitrospirae	F	Formate--tetrahydrofolate ligase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR34280931_k127_1159256_50	330214.NIDE3712	1.073e-171	541.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR34280931_k127_1159256_35	330214.NIDE3711	2.419e-210	656.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR34280931_k127_1159256_1	330214.NIDE3705	0.0	1502.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	aoxB	-	1.20.2.1,1.20.9.1	ko:K08356	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.6	-	-	Molybdopterin,Molydop_binding
SRR34280931_k127_1159256_97	330214.NIDE3704	3.394e-83	279.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	aoxA	-	1.20.2.1,1.20.9.1	ko:K08355	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.6	-	-	Rieske,TAT_signal
SRR34280931_k127_1159256_17	330214.NIDE3703	1.401e-293	905.0	2ESX4@1|root,33KFG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_39	330214.NIDE3702	1.939e-198	623.0	COG0306@1|root,COG0306@2|Bacteria,3J1D1@40117|Nitrospirae	40117|Nitrospirae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR34280931_k127_1159256_40	330214.NIDE3701	2.273e-197	618.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
SRR34280931_k127_1159256_147	240016.ABIZ01000001_gene4647	2.76e-16	83.0	COG0640@1|root,COG0640@2|Bacteria,46W65@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR34280931_k127_1159256_32	330214.NIDE3699	6.615e-225	700.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
SRR34280931_k127_1159256_138	385682.AFSL01000081_gene1020	1.807e-33	134.0	COG3370@1|root,COG3370@2|Bacteria,4NP8Y@976|Bacteroidetes	976|Bacteroidetes	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_122	502025.Hoch_2081	6.867e-46	174.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2Z1X0@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR34280931_k127_1159256_75	1128427.KB904821_gene1866	1.898e-123	402.0	COG1715@1|root,COG1715@2|Bacteria,1G3FW@1117|Cyanobacteria,1HA8S@1150|Oscillatoriales	1117|Cyanobacteria	L	COG1715 Restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
SRR34280931_k127_1159256_95	330214.NIDE3686	2.015e-85	284.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR34280931_k127_1159256_80	330214.NIDE3685	2.52e-109	355.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR34280931_k127_1159256_87	330214.NIDE3684	2.647e-92	308.0	COG3806@1|root,COG3806@2|Bacteria	2|Bacteria	T	Anti-sigma factor	-	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7
SRR34280931_k127_1159256_119	330214.NIDE3683	1.926e-47	173.0	2CNK3@1|root,32SH9@2|Bacteria	2|Bacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR34280931_k127_1159256_115	292415.Tbd_1308	3.984e-54	196.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VRBM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR34280931_k127_1159256_127	330214.NIDE3682	6.356e-43	161.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
SRR34280931_k127_1159256_55	330214.NIDE3680	1.922e-164	520.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR34280931_k127_1159256_91	330214.NIDE3677	6.732e-90	300.0	297W1@1|root,2ZV2M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR34280931_k127_1159256_41	330214.NIDE3676	1.742e-196	614.0	2DBP7@1|root,2ZA82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_63	330214.NIDE3675	3.867e-143	458.0	2DKWD@1|root,30KRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRR34280931_k127_1159256_156	330214.NIDE3673	1.514e-07	56.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3673|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_64	330214.NIDE3664	5.473e-143	460.0	COG0679@1|root,COG0679@2|Bacteria,3J1EB@40117|Nitrospirae	40117|Nitrospirae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR34280931_k127_1159256_27	330214.NIDE3663	2.46e-251	778.0	COG0477@1|root,COG2814@2|Bacteria,3J1CK@40117|Nitrospirae	40117|Nitrospirae	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
SRR34280931_k127_1159256_69	330214.NIDE3662	3.78e-135	436.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3662|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_100	330214.NIDE3657	1.431e-80	272.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR34280931_k127_1159256_134	330214.NIDE3656	1.161e-36	144.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR34280931_k127_1159256_117	330214.NIDE3653	1.165e-53	190.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	NTF2,SnoaL_2
SRR34280931_k127_1159256_137	330214.NIDE3652	1.894e-35	140.0	COG3305@1|root,COG3305@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
SRR34280931_k127_1159256_77	330214.NIDE3650	1.107e-121	395.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SRR34280931_k127_1159256_65	330214.NIDE3649	3.318e-141	452.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR34280931_k127_1159256_78	330214.NIDE3647	2.062e-117	378.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	PagL
SRR34280931_k127_1159256_66	330214.NIDE3643	9.109e-141	447.0	COG0221@1|root,COG0221@2|Bacteria,3J184@40117|Nitrospirae	40117|Nitrospirae	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR34280931_k127_1159256_11	330214.NIDE3642	0.0	1036.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	deaD	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR34280931_k127_1159256_53	1123060.JONP01000001_gene1440	5.637e-165	531.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,2TUK5@28211|Alphaproteobacteria,2JVMT@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR34280931_k127_1159256_13	330214.NIDE3639	0.0	1007.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR34280931_k127_1159256_103	330214.NIDE3638	3.54e-73	254.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR34280931_k127_1159256_9	330214.NIDE3635	0.0	1078.0	COG4108@1|root,COG4108@2|Bacteria,3J0WP@40117|Nitrospirae	40117|Nitrospirae	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
SRR34280931_k127_1159256_102	402777.KB235903_gene1500	3.542e-80	293.0	COG1807@1|root,COG1807@2|Bacteria,1G4VM@1117|Cyanobacteria,1H8JJ@1150|Oscillatoriales	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_85	572477.Alvin_0466	1.481e-95	329.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
SRR34280931_k127_1159256_135	330214.NIDE3630	2.981e-36	145.0	COG4628@1|root,COG4628@2|Bacteria	2|Bacteria	S	conserved protein (DUF2132)	YPO1157	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K06867	-	-	-	-	ko00000	-	-	-	VF530
SRR34280931_k127_1159256_86	243233.MCA1632	8.305e-93	333.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR34280931_k127_1159256_88	330214.NIDE3629	2.892e-92	306.0	COG4681@1|root,COG4681@2|Bacteria	2|Bacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
SRR34280931_k127_1159256_110	330214.NIDE3628	3.655e-60	209.0	COG0023@1|root,COG0023@2|Bacteria	2|Bacteria	J	translation initiation factor activity	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR34280931_k127_1159256_48	330214.NIDE3627	2.291e-176	558.0	COG4335@1|root,COG4335@2|Bacteria	2|Bacteria	L	DNA alkylation repair	yhaZ	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR34280931_k127_1159256_82	330214.NIDE3625	4.149e-108	352.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE3625|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_57	330214.NIDE3623	1.349e-159	505.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	ytbE	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,DUF4157
SRR34280931_k127_1159256_23	330214.NIDE3622	8.465e-269	835.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
SRR34280931_k127_1159256_108	330214.NIDE3620	3.411e-61	216.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	aac	GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
SRR34280931_k127_1159256_104	330214.NIDE3619	1.1e-69	238.0	29KDN@1|root,307AY@2|Bacteria,3J14Y@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_31	330214.NIDE3618	9.169e-226	703.0	COG2081@1|root,COG2081@2|Bacteria	2|Bacteria	N	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR34280931_k127_1159256_113	640081.Dsui_3209	1.578e-57	207.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2VTCX@28216|Betaproteobacteria,2KWGZ@206389|Rhodocyclales	206389|Rhodocyclales	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
SRR34280931_k127_1159256_142	330214.NIDE3616	1.447e-27	118.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.1.53	ko:K11206,ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR34280931_k127_1159256_73	330214.NIDE2515	2.853e-125	441.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2,DUF3971,DUF748
SRR34280931_k127_1159256_157	1123392.AQWL01000001_gene1623	0.0006279	48.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUCR@28216|Betaproteobacteria,1KTE4@119069|Hydrogenophilales	119069|Hydrogenophilales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR34280931_k127_1159256_33	330214.NIDE3615	3.834e-218	682.0	COG2081@1|root,COG2081@2|Bacteria,3J12U@40117|Nitrospirae	40117|Nitrospirae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR34280931_k127_1159256_52	330214.NIDE3614	5.33e-165	525.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SRR34280931_k127_1159256_38	330214.NIDE3612	3.431e-201	632.0	2C8FN@1|root,2ZBER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_54	330214.NIDE3609	1.421e-164	521.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR34280931_k127_1159256_22	330214.NIDE3608	2.594e-269	832.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874,Glyco_hydro_42
SRR34280931_k127_1159256_59	330214.NIDE3607	4.951e-156	498.0	COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
SRR34280931_k127_1159256_72	330214.NIDE3605	5.769e-129	414.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N,Pro_isomerase
SRR34280931_k127_1159256_49	330214.NIDE3604	2.669e-175	552.0	COG0435@1|root,COG0435@2|Bacteria	2|Bacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7,2.5.1.18	ko:K00799,ko:K07393	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373	GST_C_2,GST_N_2
SRR34280931_k127_1159256_46	330214.NIDE3598	1.169e-179	565.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR34280931_k127_1159256_25	330214.NIDE3595	7.49e-265	822.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	putP	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	SSF
SRR34280931_k127_1159256_6	330214.NIDE3593	0.0	1345.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_1159256_21	330214.NIDE3592	2.946e-272	842.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR34280931_k127_1159256_5	330214.NIDE3591	0.0	1345.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR34280931_k127_1159256_96	330214.NIDE3590	6.27e-85	283.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
SRR34280931_k127_1159256_42	330214.NIDE3589	4.79e-196	619.0	COG0628@1|root,COG0628@2|Bacteria,3J0SZ@40117|Nitrospirae	40117|Nitrospirae	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR34280931_k127_1159256_116	330214.NIDE0375	6.192e-54	196.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4041,GGDEF,HATPase_c,HisKA,Response_reg,T5orf172,dCache_1
SRR34280931_k127_1159256_3	330214.NIDE3587	0.0	1396.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_9,PilJ,Response_reg,SpoIIE
SRR34280931_k127_1159256_125	330214.NIDE0542	8.619e-44	173.0	COG0745@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_1159256_93	330214.NIDE3585	1.717e-86	286.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PIG-L,Response_reg
SRR34280931_k127_1159256_150	330214.NIDE3584	5.566e-12	67.0	2DGQ2@1|root,2ZWWE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_129	330214.NIDE3583	4.59e-41	153.0	COG0271@1|root,COG0271@2|Bacteria	2|Bacteria	T	Belongs to the BolA IbaG family	bolA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K05527,ko:K22066	-	-	-	-	ko00000,ko03000,ko03029	-	-	-	BolA
SRR34280931_k127_1159256_106	330214.NIDE3582	2.679e-65	223.0	COG0278@1|root,COG0278@2|Bacteria	2|Bacteria	O	protein disulfide oxidoreductase activity	grxD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	iPC815.YPO2383,iYL1228.KPN_01992	Glutaredoxin
SRR34280931_k127_1159256_26	330214.NIDE3581	2.823e-257	799.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
SRR34280931_k127_1159256_68	330214.NIDE3580	8.683e-137	439.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE3580|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR34280931_k127_1159256_74	330214.NIDE3579	7.84e-125	403.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR34280931_k127_1159256_81	330214.NIDE3577	2.066e-108	355.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Glycos_transf_2
SRR34280931_k127_1159256_30	330214.NIDE3575	1.423e-233	724.0	COG0717@1|root,COG0717@2|Bacteria,3J0WG@40117|Nitrospirae	40117|Nitrospirae	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR34280931_k127_1159256_29	330214.NIDE3574	2.7e-243	753.0	COG1509@1|root,COG1509@2|Bacteria,3J0W3@40117|Nitrospirae	40117|Nitrospirae	C	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C,Radical_SAM
SRR34280931_k127_1159256_124	330214.NIDE3573	3.808e-44	160.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
SRR34280931_k127_1159256_18	330214.NIDE3572	3.122e-291	902.0	28MGX@1|root,2ZATZ@2|Bacteria,3J0YU@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1159256_47	330214.NIDE3571	9.198e-177	561.0	COG0727@1|root,COG4866@1|root,COG0727@2|Bacteria,COG4866@2|Bacteria	2|Bacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163,ko:K06940	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,CxxCxxCC,DUF2156
SRR34280931_k127_1161526_11	330214.NIDE0950	1.454e-75	257.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR34280931_k127_1161526_3	330214.NIDE0948	1.921e-210	663.0	COG0457@1|root,COG0790@1|root,COG0457@2|Bacteria,COG0790@2|Bacteria,3J1CG@40117|Nitrospirae	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02450,ko:K07126	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	Sel1
SRR34280931_k127_1161526_1	330214.NIDE0947	0.0	1333.0	COG3829@1|root,COG4252@1|root,COG3829@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,HTH_8,Sigma54_activat
SRR34280931_k127_1161526_4	330214.NIDE0946	5.832e-205	643.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	hemK1	-	-	-	-	-	-	-	-	-	-	-	MTS,PrmA
SRR34280931_k127_1161526_6	330214.NIDE0942	2.474e-112	372.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OMP_b-brl,OmpA
SRR34280931_k127_1161526_2	330214.NIDE0941	0.0	1019.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR34280931_k127_1161526_7	330214.NIDE0940	9.459e-89	301.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR34280931_k127_1161526_0	330214.NIDE1804	0.0	1418.0	COG3696@1|root,COG3696@2|Bacteria,3J0ZR@40117|Nitrospirae	40117|Nitrospirae	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR34280931_k127_1161526_17	96561.Dole_1815	5.65e-09	63.0	COG4634@1|root,COG4634@2|Bacteria,1RH7A@1224|Proteobacteria,42U78@68525|delta/epsilon subdivisions,2WQJY@28221|Deltaproteobacteria,2MM7D@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1161526_14	1469607.KK073768_gene4182	1.284e-12	71.0	COG2442@1|root,COG2442@2|Bacteria,1GKGQ@1117|Cyanobacteria,1HPA1@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR34280931_k127_1161526_19	330214.NIDE2279	3.599e-06	53.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_1161526_16	102129.Lepto7375DRAFT_1420	8.074e-10	69.0	2CIT6@1|root,31XCJ@2|Bacteria,1G71K@1117|Cyanobacteria,1HBR0@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1161526_10	102125.Xen7305DRAFT_00040250	1.007e-75	268.0	COG0641@1|root,COG0641@2|Bacteria,1GAI2@1117|Cyanobacteria	1117|Cyanobacteria	C	Radical SAM additional 4Fe4S-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR34280931_k127_1161526_8	102125.Xen7305DRAFT_00040260	2.372e-87	308.0	COG0367@1|root,COG0367@2|Bacteria,1GBXI@1117|Cyanobacteria	1117|Cyanobacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	-
SRR34280931_k127_1161526_13	102125.Xen7305DRAFT_00040240	1.785e-27	122.0	2CIT6@1|root,31XCJ@2|Bacteria,1G71K@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1161526_5	330214.NIDE0337	1.748e-186	584.0	COG2946@1|root,COG2946@2|Bacteria	2|Bacteria	L	Replication initiation factor	nicK	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
SRR34280931_k127_1199739_13	330214.NIDE2751	2.213e-76	258.0	COG1259@1|root,COG1259@2|Bacteria,3J0RC@40117|Nitrospirae	40117|Nitrospirae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR34280931_k127_1199739_16	330214.NIDE2750	5.406e-55	193.0	COG2924@1|root,COG2924@2|Bacteria,3J1CU@40117|Nitrospirae	40117|Nitrospirae	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR34280931_k127_1199739_17	330214.NIDE2748	8.781e-41	151.0	COG0425@1|root,COG0425@2|Bacteria,3J1DD@40117|Nitrospirae	40117|Nitrospirae	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR34280931_k127_1199739_11	330214.NIDE2747	6.123e-100	332.0	COG0313@1|root,COG0313@2|Bacteria,3J0PU@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR34280931_k127_1199739_8	330214.NIDE2746	3.05e-161	510.0	COG0755@1|root,COG0755@2|Bacteria,3J14H@40117|Nitrospirae	40117|Nitrospirae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR34280931_k127_1199739_3	330214.NIDE2745	1.563e-271	840.0	COG0373@1|root,COG0373@2|Bacteria,3J0BD@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR34280931_k127_1199739_7	330214.NIDE2744	4.455e-165	523.0	COG0181@1|root,COG0181@2|Bacteria,3J0GC@40117|Nitrospirae	40117|Nitrospirae	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR34280931_k127_1199739_1	330214.NIDE2743	4.961e-283	877.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3J0B6@40117|Nitrospirae	40117|Nitrospirae	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR34280931_k127_1199739_15	330214.NIDE2742	3.612e-75	253.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	opuCA	-	2.7.7.7	ko:K02342,ko:K05847,ko:K07182	ko00230,ko00240,ko01100,ko02010,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02010,map03030,map03430,map03440	M00209,M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02000,ko03032,ko03400	3.A.1.12	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR34280931_k127_1199739_5	330214.NIDE2741	4.667e-193	605.0	COG0113@1|root,COG0113@2|Bacteria,3J0DV@40117|Nitrospirae	40117|Nitrospirae	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR34280931_k127_1199739_6	330214.NIDE2740	3.209e-174	553.0	COG0196@1|root,COG0196@2|Bacteria,3J0KY@40117|Nitrospirae	40117|Nitrospirae	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR34280931_k127_1199739_4	330214.NIDE2739	1.201e-198	629.0	COG0037@1|root,COG0037@2|Bacteria,3J0SX@40117|Nitrospirae	40117|Nitrospirae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR34280931_k127_1199739_10	330214.NIDE2738	5.031e-107	352.0	COG0634@1|root,COG0634@2|Bacteria,3J0NZ@40117|Nitrospirae	40117|Nitrospirae	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR34280931_k127_1199739_0	330214.NIDE2737	0.0	1190.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	40117|Nitrospirae	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR34280931_k127_1199739_14	644282.Deba_0763	5.084e-76	265.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR34280931_k127_1199739_2	330214.NIDE2735	6.936e-282	867.0	COG1109@1|root,COG1109@2|Bacteria,3J0E7@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR34280931_k127_1199739_12	330214.NIDE2734	3.32e-78	266.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3J0VB@40117|Nitrospirae	40117|Nitrospirae	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
SRR34280931_k127_120062_15	330214.NIDE0290	2.455e-41	156.0	COG2946@1|root,COG2946@2|Bacteria	2|Bacteria	L	Replication initiation factor	nicK	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
SRR34280931_k127_120062_20	4113.PGSC0003DMT400007977	1.549e-11	75.0	COG5641@1|root,KOG1601@2759|Eukaryota,37T81@33090|Viridiplantae,3GHSU@35493|Streptophyta,44R8M@71274|asterids	35493|Streptophyta	K	cheY-homologous receiver domain	-	GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0007154,GO:0007165,GO:0007623,GO:0008150,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009755,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0032870,GO:0035556,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048511,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071368,GO:0071495,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K14492	ko04075,map04075	-	-	-	ko00000,ko00001	-	-	-	Response_reg
SRR34280931_k127_120062_25	1333856.L686_01780	0.0001326	51.0	COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,1RNEY@1236|Gammaproteobacteria,1Z1GC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	corR	-	-	ko:K04333	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GerE
SRR34280931_k127_120062_14	330214.NIDE2108	3.505e-42	166.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2108|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_120062_7	330214.NIDE2109	5.918e-85	298.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR34280931_k127_120062_8	330214.NIDE2110	5.013e-78	271.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR34280931_k127_120062_3	330214.NIDE2111	5.862e-211	662.0	COG4962@1|root,COG4962@2|Bacteria	2|Bacteria	U	Type ii secretion system protein e	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR34280931_k127_120062_10	330214.NIDE2112	2.405e-59	215.0	COG4963@1|root,COG4963@2|Bacteria	2|Bacteria	-	-	cpaE1	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR34280931_k127_120062_6	330214.NIDE2113	3.386e-99	334.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
SRR34280931_k127_120062_12	330214.NIDE2114	5.061e-44	166.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR34280931_k127_120062_4	330214.NIDE2116	4.566e-178	570.0	COG4964@1|root,COG4964@2|Bacteria	2|Bacteria	U	Pilus formation protein N terminal region	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
SRR34280931_k127_120062_9	330214.NIDE2117	3.08e-70	252.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR34280931_k127_120062_17	330214.NIDE2118	2.235e-33	135.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pilD	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR34280931_k127_120062_26	1120792.JAFV01000001_gene3171	0.0003798	44.0	2AGR2@1|root,316YT@2|Bacteria,1NIQT@1224|Proteobacteria,2UJAY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Flp/Fap pilin component	-	-	-	-	-	-	-	-	-	-	-	-	Flp_Fap
SRR34280931_k127_120062_2	330214.NIDE2119	5.423e-216	684.0	COG2172@1|root,COG2199@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315,ko:K20977	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00820	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	HATPase_c_2,PAS_9,Response_reg,SpoIIE
SRR34280931_k127_120062_18	330214.NIDE2120	3.388e-32	128.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749,ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko03021	-	-	-	STAS,STAS_2
SRR34280931_k127_120062_16	330214.NIDE2345	4.748e-36	138.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	ylxH-3	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
SRR34280931_k127_120062_23	1056820.KB900653_gene3057	2.927e-08	60.0	2F7D8@1|root,33ZU9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_120062_24	1056820.KB900653_gene3057	4.046e-05	47.0	2F7D8@1|root,33ZU9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_120062_21	330214.NIDE2279	2.459e-10	62.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_120062_0	330214.NIDE2267	1.608e-279	863.0	COG2204@1|root,COG2204@2|Bacteria,3J0ZU@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_120062_5	330214.NIDE2266	7.181e-113	370.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	yttA	-	2.7.13.3	ko:K07184,ko:K07777,ko:K12065,ko:K13527	ko02020,ko03050,map02020,map03050	M00342,M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02044,ko03051	3.A.7.11.1	-	-	DUF3102,DUF3450
SRR34280931_k127_120062_1	330214.NIDE2265	3.635e-251	780.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR34280931_k127_1201608_7	330214.NIDE0468	2.62e-150	479.0	COG0364@1|root,COG0364@2|Bacteria,3J0XD@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR34280931_k127_1201608_0	330214.NIDE0462	4.512e-289	891.0	COG4949@1|root,COG4949@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
SRR34280931_k127_1201608_9	330214.NIDE0460	3.544e-120	390.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	2|Bacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR34280931_k127_1201608_16	330214.NIDE0458	1.363e-54	192.0	COG3041@1|root,COG3041@2|Bacteria	2|Bacteria	S	endonuclease activity	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
SRR34280931_k127_1201608_18	330214.NIDE0457	3.943e-45	167.0	COG3077@1|root,COG3077@2|Bacteria	2|Bacteria	L	bacterial-type proximal promoter sequence-specific DNA binding	relB1	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
SRR34280931_k127_1201608_21	1379698.RBG1_1C00001G1696	1.79e-05	51.0	COG0590@1|root,COG0590@2|Bacteria,2NPM7@2323|unclassified Bacteria	2|Bacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
SRR34280931_k127_1201608_11	330214.NIDE0447	1.17e-94	312.0	COG0703@1|root,COG0703@2|Bacteria,3J0R8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR34280931_k127_1201608_6	330214.NIDE0446	2.949e-169	533.0	COG0169@1|root,COG0169@2|Bacteria,3J0SM@40117|Nitrospirae	40117|Nitrospirae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR34280931_k127_1201608_8	330214.NIDE0445	1.803e-148	475.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE0445|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1201608_4	330214.NIDE0444	2.729e-175	551.0	COG2519@1|root,COG2519@2|Bacteria,3J0PT@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR34280931_k127_1201608_2	330214.NIDE0443	3.924e-221	690.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR34280931_k127_1201608_3	330214.NIDE0442	1.72e-180	572.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_1201608_10	330214.NIDE0441	1.359e-108	357.0	COG0321@1|root,COG0321@2|Bacteria	2|Bacteria	H	lipoyl(octanoyl) transferase activity	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
SRR34280931_k127_1201608_1	330214.NIDE0440	4.521e-250	777.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR34280931_k127_1201608_12	330214.NIDE0437	5.936e-77	262.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR34280931_k127_1201608_5	330214.NIDE0436	4.263e-170	539.0	COG0583@1|root,COG0583@2|Bacteria,3J16P@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulator	-	-	-	ko:K11921,ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR34280931_k127_1202757_13	1245471.PCA10_28800	1.919e-08	59.0	2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2523
SRR34280931_k127_1202757_12	1123279.ATUS01000001_gene2720	2.476e-18	97.0	COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zonular occludens toxin (Zot)	-	-	-	ko:K10954	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	Zot
SRR34280931_k127_1202757_11	1356854.N007_16670	2.019e-34	138.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,4HG4Q@91061|Bacilli,27ANZ@186823|Alicyclobacillaceae	91061|Bacilli	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR34280931_k127_1202757_9	330214.NIDE4233	1.335e-54	207.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
SRR34280931_k127_1202757_14	1121447.JONL01000001_gene735	0.0001065	48.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1202757_2	330214.NIDE2280	2.634e-296	911.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	fleQ	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1202757_0	330214.NIDE2282	0.0	1114.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2282|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1202757_4	330214.NIDE2283	3.203e-218	683.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	gnfL	-	2.7.13.3	ko:K07708,ko:K07710,ko:K10942	ko02020,ko05111,map02020,map05111	M00497,M00500,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
SRR34280931_k127_1202757_3	330214.NIDE2284	2.007e-276	853.0	COG2204@1|root,COG2204@2|Bacteria,3J0FP@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1202757_8	330214.NIDE2285	1.897e-69	241.0	COG1815@1|root,COG1815@2|Bacteria,3J0R3@40117|Nitrospirae	40117|Nitrospirae	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
SRR34280931_k127_1202757_7	330214.NIDE2286	8.1e-83	276.0	COG1558@1|root,COG1558@2|Bacteria,3J0TK@40117|Nitrospirae	40117|Nitrospirae	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR34280931_k127_1202757_10	330214.NIDE2287	1.211e-47	173.0	COG1677@1|root,COG1677@2|Bacteria,3J0UT@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
SRR34280931_k127_1202757_1	330214.NIDE2288	8.403e-302	929.0	COG1766@1|root,COG1766@2|Bacteria,3J0A6@40117|Nitrospirae	40117|Nitrospirae	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
SRR34280931_k127_1202757_5	330214.NIDE2289	1.009e-194	609.0	COG1536@1|root,COG1536@2|Bacteria,3J0GZ@40117|Nitrospirae	40117|Nitrospirae	N	FliG middle domain	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
SRR34280931_k127_1202757_6	330214.NIDE2290	5.52e-125	404.0	COG1317@1|root,COG2204@1|root,COG1317@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	hrpE	-	-	ko:K02411,ko:K03223,ko:K03413	ko02020,ko02030,ko02040,ko03070,map02020,map02030,map02040,map03070	M00332,M00506,M00660	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliH,HrpE,NolV,Response_reg,TPR_16,TPR_19
SRR34280931_k127_1205272_2	1123278.KB893554_gene3963	2.059e-17	84.0	COG2026@1|root,COG2026@2|Bacteria,4NVIF@976|Bacteroidetes,47SMY@768503|Cytophagia	976|Bacteroidetes	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR34280931_k127_1205272_1	671143.DAMO_0603	1.017e-22	98.0	2C2YU@1|root,33M8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1205272_0	1162668.LFE_2072	5.737e-137	448.0	COG2801@1|root,COG2801@2|Bacteria,3J1E8@40117|Nitrospirae	2|Bacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
SRR34280931_k127_1236125_3	330214.NIDE2997	8.615e-84	278.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR34280931_k127_1236125_1	330214.NIDE2996	2.408e-259	810.0	COG0438@1|root,COG0438@2|Bacteria,3J0ZX@40117|Nitrospirae	40117|Nitrospirae	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1236125_0	330214.NIDE2995	0.0	1049.0	COG0367@1|root,COG0367@2|Bacteria,3J0XS@40117|Nitrospirae	40117|Nitrospirae	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_1236125_4	925409.KI911562_gene150	2.164e-80	279.0	COG2227@1|root,COG2227@2|Bacteria,4NNQC@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR34280931_k127_1236125_2	330214.NIDE2993	6.993e-231	718.0	COG0438@1|root,COG0438@2|Bacteria,3J0X1@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR34280931_k127_1236125_5	1380394.JADL01000007_gene4621	9.915e-38	157.0	COG2227@1|root,COG2227@2|Bacteria,1NKIZ@1224|Proteobacteria,2UKY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR34280931_k127_1256248_64	330214.NIDE2123	5.492e-06	49.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_29,rve,rve_3
SRR34280931_k127_1256248_12	330214.NIDE1224	2.244e-203	635.0	COG0150@1|root,COG0150@2|Bacteria,3J0DR@40117|Nitrospirae	40117|Nitrospirae	F	AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR34280931_k127_1256248_31	330214.NIDE1225	1.08e-112	367.0	COG0299@1|root,COG0299@2|Bacteria,3J0MC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR34280931_k127_1256248_58	909663.KI867150_gene89	1.021e-29	123.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR34280931_k127_1256248_51	330214.NIDE3236	3.797e-50	179.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
SRR34280931_k127_1256248_55	330214.NIDE1226	3.881e-38	145.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
SRR34280931_k127_1256248_2	330214.NIDE1227	0.0	1003.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.13.3	ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
SRR34280931_k127_1256248_13	330214.NIDE1228	9.828e-203	637.0	COG2199@1|root,COG3706@2|Bacteria,3J188@40117|Nitrospirae	40117|Nitrospirae	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR34280931_k127_1256248_30	330214.NIDE1229	2.351e-115	374.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K03413,ko:K07315	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03021	-	-	-	GGDEF,HATPase_c,HATPase_c_2,HisKA,Response_reg
SRR34280931_k127_1256248_41	330214.NIDE1230	8.663e-74	251.0	COG1610@1|root,COG1610@2|Bacteria,3J1F3@40117|Nitrospirae	40117|Nitrospirae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR34280931_k127_1256248_8	330214.NIDE1232	8.346e-234	730.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	lacY	-	-	ko:K02532,ko:K05820,ko:K08167,ko:K08218,ko:K08369	ko01501,map01501	M00628,M00713,M00714	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.1,2.A.1.25,2.A.1.27,2.A.1.3,2.A.1.5	-	-	LacY_symp,MFS_1
SRR34280931_k127_1256248_36	330214.NIDE1235	4.301e-99	329.0	COG0386@1|root,COG0386@2|Bacteria	2|Bacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.22,1.11.1.9	ko:K00432,ko:K20207	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	iJN678.slr1992	GSHPx
SRR34280931_k127_1256248_16	330214.NIDE1236	6.081e-185	580.0	COG0501@1|root,COG0501@2|Bacteria,3J0QG@40117|Nitrospirae	40117|Nitrospirae	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR34280931_k127_1256248_46	330214.NIDE1237	2.433e-62	217.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14588	-	-	-	-	ko00000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,SoxE
SRR34280931_k127_1256248_19	1288494.EBAPG3_22730	5.358e-160	510.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,2VQQ2@28216|Betaproteobacteria,374P4@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
SRR34280931_k127_1256248_49	330214.NIDE1240	1.305e-56	198.0	COG2768@1|root,COG2768@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088,DUF362
SRR34280931_k127_1256248_43	330214.NIDE1241	2.807e-68	234.0	2ETP6@1|root,33M6W@2|Bacteria,3J18I@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_44	330214.NIDE1242	2.225e-64	223.0	COG3411@1|root,COG3411@2|Bacteria,3J1DT@40117|Nitrospirae	40117|Nitrospirae	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_47	330214.NIDE1243	3.742e-61	213.0	2CDBX@1|root,2ZUMJ@2|Bacteria,3J1B0@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_14	330214.NIDE1244	5.421e-202	634.0	COG0686@1|root,COG0686@2|Bacteria	2|Bacteria	E	alanine dehydrogenase activity	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
SRR34280931_k127_1256248_66	436229.JOEH01000009_gene4564	0.0002263	45.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
SRR34280931_k127_1256248_54	330214.NIDE1245	2.067e-42	156.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
SRR34280931_k127_1256248_15	330214.NIDE1246	4.943e-187	589.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SRR34280931_k127_1256248_37	330214.NIDE1247	6.387e-96	315.0	COG0503@1|root,COG0503@2|Bacteria,3J14T@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR34280931_k127_1256248_35	330214.NIDE1248	2.383e-102	334.0	COG1734@1|root,COG1734@2|Bacteria,3J0R1@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR34280931_k127_1256248_27	330214.NIDE1249	4.716e-123	398.0	COG0603@1|root,COG0603@2|Bacteria,3J0NP@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR34280931_k127_1256248_42	330214.NIDE1251	6.424e-70	239.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR34280931_k127_1256248_18	330214.NIDE1252	4.519e-167	526.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR34280931_k127_1256248_38	330214.NIDE2246	1.008e-92	316.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR34280931_k127_1256248_1	330214.NIDE1254	0.0	1299.0	COG1640@1|root,COG1640@2|Bacteria,3J106@40117|Nitrospirae	40117|Nitrospirae	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR34280931_k127_1256248_11	330214.NIDE1255	2.703e-205	646.0	COG4191@1|root,COG4191@2|Bacteria,3J14D@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRR34280931_k127_1256248_6	330214.NIDE1256	2.101e-269	834.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1256248_52	330214.NIDE1258	2.01e-48	173.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR34280931_k127_1256248_25	330214.NIDE1259	5.28e-139	461.0	2AKRW@1|root,31BIT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_45	330214.NIDE1261	1.488e-62	218.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR34280931_k127_1256248_28	330214.NIDE1263	3.566e-122	395.0	29A8R@1|root,2ZX9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_56	383372.Rcas_1675	9.965e-38	145.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR34280931_k127_1256248_5	330214.NIDE0928	7.406e-278	862.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,VanY,YkuD
SRR34280931_k127_1256248_22	330214.NIDE0927	2.008e-152	484.0	COG2175@1|root,COG2175@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	tfdA	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
SRR34280931_k127_1256248_20	330214.NIDE0926	2.4e-159	504.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR34280931_k127_1256248_0	330214.NIDE0925	0.0	1330.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria	2|Bacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
SRR34280931_k127_1256248_4	330214.NIDE0923	1.208e-291	914.0	2DD94@1|root,2ZH4B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1256248_26	330214.NIDE1274	8.323e-135	440.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_1256248_3	330214.NIDE1277	1.729e-304	939.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
SRR34280931_k127_1256248_23	330214.NIDE1278	1.786e-147	468.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
SRR34280931_k127_1256248_17	330214.NIDE1279	6.748e-182	573.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
SRR34280931_k127_1256248_32	330214.NIDE1284	5.047e-109	355.0	COG0797@1|root,COG0797@2|Bacteria	2|Bacteria	M	peptidoglycan binding	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,LysM
SRR34280931_k127_1256248_21	330214.NIDE1286	5.719e-159	504.0	COG1413@1|root,COG1413@2|Bacteria,3J1E2@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_1256248_10	330214.NIDE1288	1.31e-212	669.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
SRR34280931_k127_1256248_9	330214.NIDE1289	1.057e-231	717.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR34280931_k127_1267586_22	1356854.N007_16670	1.333e-33	135.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,4HG4Q@91061|Bacilli,27ANZ@186823|Alicyclobacillaceae	91061|Bacilli	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR34280931_k127_1267586_13	330214.NIDE4010	1.445e-116	391.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
SRR34280931_k127_1267586_3	330214.NIDE3548	2.002e-282	870.0	COG0104@1|root,COG0104@2|Bacteria,3J0FV@40117|Nitrospirae	40117|Nitrospirae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR34280931_k127_1267586_2	330214.NIDE3551	0.0	1130.0	COG0488@1|root,COG0488@2|Bacteria,3J0W6@40117|Nitrospirae	40117|Nitrospirae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR34280931_k127_1267586_5	330214.NIDE3553	3.137e-245	762.0	COG2256@1|root,COG2256@2|Bacteria,3J0H6@40117|Nitrospirae	40117|Nitrospirae	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR34280931_k127_1267586_10	330214.NIDE3554	1.211e-133	432.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR34280931_k127_1267586_11	330214.NIDE3555	2.128e-128	411.0	COG0302@1|root,COG0302@2|Bacteria,3J0Q0@40117|Nitrospirae	40117|Nitrospirae	F	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR34280931_k127_1267586_21	1356854.N007_10880	4.341e-39	150.0	COG0720@1|root,COG0720@2|Bacteria,1UZVB@1239|Firmicutes,4H9SV@91061|Bacilli	91061|Bacilli	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR34280931_k127_1267586_19	330214.NIDE3558	7.03e-62	214.0	COG0316@1|root,COG0316@2|Bacteria,3J0TZ@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the HesB IscA family	-	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
SRR34280931_k127_1267586_17	330214.NIDE3559	4.508e-67	229.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
SRR34280931_k127_1267586_4	330214.NIDE3560	1.447e-278	857.0	COG1894@1|root,COG1894@2|Bacteria,3J0WA@40117|Nitrospirae	40117|Nitrospirae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR34280931_k127_1267586_12	330214.NIDE3561	1.285e-121	391.0	COG3748@1|root,COG3748@2|Bacteria,3J19B@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:DUF989	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR34280931_k127_1267586_8	330214.NIDE3562	1.605e-184	580.0	COG0039@1|root,COG0039@2|Bacteria,3J0EG@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR34280931_k127_1267586_14	330214.NIDE3563	1.721e-85	284.0	2DESJ@1|root,2ZP2P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1267586_1	330214.NIDE3564	0.0	1683.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
SRR34280931_k127_1267586_15	330214.NIDE3565	5.364e-85	282.0	COG4802@1|root,COG4802@2|Bacteria	2|Bacteria	C	ferredoxin-thioredoxin reductase activity	ftrC	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	1.8.7.2	ko:K17892	-	-	-	-	ko00000,ko01000	-	-	-	FeThRed_B
SRR34280931_k127_1267586_7	330214.NIDE3566	9.873e-192	607.0	COG2234@1|root,COG2234@2|Bacteria,3J1BG@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR34280931_k127_1267586_20	330214.NIDE3568	2.597e-39	149.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR34280931_k127_1267586_9	330214.NIDE3569	4.554e-171	539.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
SRR34280931_k127_1267586_0	330214.NIDE3570	0.0	1942.0	COG2203@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_1267586_6	330214.NIDE3571	2.446e-234	738.0	COG0727@1|root,COG4866@1|root,COG0727@2|Bacteria,COG4866@2|Bacteria	2|Bacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163,ko:K06940	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,CxxCxxCC,DUF2156
SRR34280931_k127_1267586_24	330214.NIDE3572	1.585e-16	80.0	28MGX@1|root,2ZATZ@2|Bacteria,3J0YU@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1272579_12	330214.NIDE2667	1.325e-62	220.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	bluB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.79,2.4.2.21	ko:K00768,ko:K04719	ko00740,ko00860,ko01100,map00740,map00860,map01100	M00122	R04148,R09083	RC00033,RC00063,RC00435,RC02413	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
SRR34280931_k127_1272579_9	330214.NIDE2669	9.61e-104	340.0	COG2109@1|root,COG2109@2|Bacteria,3J0NJ@40117|Nitrospirae	40117|Nitrospirae	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR34280931_k127_1272579_1	330214.NIDE2670	4.952e-222	696.0	COG1797@1|root,COG1797@2|Bacteria,3J0HM@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
SRR34280931_k127_1272579_0	330214.NIDE2671	0.0	1151.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR34280931_k127_1272579_6	330214.NIDE2672	1.349e-132	433.0	COG1120@1|root,COG1120@2|Bacteria,3J14U@40117|Nitrospirae	40117|Nitrospirae	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR34280931_k127_1272579_4	330214.NIDE2673	3.859e-175	556.0	COG0609@1|root,COG0609@2|Bacteria,3J11Y@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR34280931_k127_1272579_2	330214.NIDE2674	3.607e-177	559.0	COG0614@1|root,COG0614@2|Bacteria,3J173@40117|Nitrospirae	40117|Nitrospirae	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR34280931_k127_1272579_16	330214.NIDE2676	2.306e-40	151.0	COG4095@1|root,COG4095@2|Bacteria,3J0UA@40117|Nitrospirae	40117|Nitrospirae	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
SRR34280931_k127_1272579_18	330214.NIDE2677	3.023e-33	128.0	COG0227@1|root,COG0227@2|Bacteria,3J0VJ@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR34280931_k127_1272579_13	330214.NIDE2678	1.197e-53	192.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
SRR34280931_k127_1272579_19	330214.NIDE2713	1.398e-12	71.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_1272579_7	330214.NIDE2896	6.129e-126	431.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
SRR34280931_k127_1272579_3	330214.NIDE0887	3.078e-176	585.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR34280931_k127_1272579_5	330214.NIDE0885	8.351e-163	522.0	COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_1272579_21	768671.ThimaDRAFT_2214	1.136e-05	58.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Lipase_GDSL_2,Metallophos,SASA,SLH
SRR34280931_k127_1272579_15	396595.TK90_2513	2.125e-43	171.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria,1WX9D@135613|Chromatiales	135613|Chromatiales	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
SRR34280931_k127_1272579_8	134676.ACPL_5635	1.238e-104	351.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR34280931_k127_1272579_10	706587.Desti_4570	1.303e-94	321.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,42PIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase like family 2	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR34280931_k127_1272579_14	344747.PM8797T_28229	2.646e-46	187.0	COG3866@1|root,COG3866@2|Bacteria,2IZ3T@203682|Planctomycetes	203682|Planctomycetes	M	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	-
SRR34280931_k127_1272579_11	706587.Desti_1774	6.152e-91	311.0	COG2755@1|root,COG2755@2|Bacteria,1NCJV@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1314444_0	330214.NIDE2210	6.079e-195	614.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4	ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515	ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100	M00037	R03130,R04905,R10060,R10061	RC00003,RC00392,RC03038,RC03040	ko00000,ko00001,ko00002,ko01000,ko01008,ko03009	-	-	-	AMP-binding,Aminotran_1_2,AviRa,Condensation,Dimerisation2,Hen1_L,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding
SRR34280931_k127_1314444_1	330214.NIDE2211	5.14e-136	441.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	rmlA	GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.7.13,2.7.7.24,2.7.7.99	ko:K00966,ko:K00973,ko:K00992	ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130	M00114,M00361,M00362,M00793	R00885,R02328,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRR34280931_k127_1319895_56	909663.KI867150_gene499	6.729e-05	48.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,438DV@68525|delta/epsilon subdivisions,2WXRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR34280931_k127_1319895_45	1116472.MGMO_118c00020	4.43e-28	117.0	COG5304@1|root,COG5304@2|Bacteria,1N9U3@1224|Proteobacteria,1SSRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
SRR34280931_k127_1319895_1	330214.NIDE3866	0.0	1502.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,3J0ZI@40117|Nitrospirae	40117|Nitrospirae	C	ATP-grasp domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR34280931_k127_1319895_37	330214.NIDE3864	2.199e-65	224.0	COG2010@1|root,COG2010@2|Bacteria,3J1AX@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
SRR34280931_k127_1319895_12	330214.NIDE3863	4.417e-168	530.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_1319895_25	330214.NIDE3861	6.291e-91	301.0	COG1499@1|root,COG1499@2|Bacteria	2|Bacteria	J	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
SRR34280931_k127_1319895_23	330214.NIDE3860	6.232e-111	370.0	COG1926@1|root,COG1926@2|Bacteria,3J18T@40117|Nitrospirae	40117|Nitrospirae	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR34280931_k127_1319895_31	330214.NIDE3859	2.672e-85	284.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR34280931_k127_1319895_20	330214.NIDE3856	5.646e-131	420.0	COG3541@1|root,COG3541@2|Bacteria	2|Bacteria	L	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
SRR34280931_k127_1319895_42	330214.NIDE3855	4.055e-36	140.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR34280931_k127_1319895_9	330214.NIDE3854	4.323e-193	612.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR34280931_k127_1319895_10	330214.NIDE3853	2.734e-183	576.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR34280931_k127_1319895_13	330214.NIDE3852	1.958e-160	516.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR34280931_k127_1319895_2	330214.NIDE3851	0.0	1060.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR34280931_k127_1319895_3	330214.NIDE3847	4.499e-294	913.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR34280931_k127_1319895_5	330214.NIDE3846	6.063e-259	801.0	COG0281@1|root,COG0281@2|Bacteria,3J0WV@40117|Nitrospirae	2|Bacteria	C	Malic enzyme, NAD binding domain	mez_1	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR34280931_k127_1319895_28	330214.NIDE3827	2.565e-87	292.0	COG2854@1|root,COG2854@2|Bacteria,3J13Z@40117|Nitrospirae	40117|Nitrospirae	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR34280931_k127_1319895_17	330214.NIDE3823	1.628e-139	451.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
SRR34280931_k127_1319895_33	330214.NIDE3822	4.62e-79	265.0	COG1881@1|root,COG1881@2|Bacteria	2|Bacteria	S	positive regulation of acetylcholine metabolic process	ybcL	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR34280931_k127_1319895_16	330214.NIDE3819	7.938e-142	458.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR34280931_k127_1319895_40	330214.NIDE3818	9.405e-55	197.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	soxX	-	-	ko:K02305,ko:K17223	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C,Cytochrome_CBB3
SRR34280931_k127_1319895_22	330214.NIDE3804	1.968e-123	398.0	COG3647@1|root,COG3647@2|Bacteria	2|Bacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR34280931_k127_1319895_26	330214.NIDE3803	4.148e-89	300.0	COG3647@1|root,COG3647@2|Bacteria	2|Bacteria	S	Membrane	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR34280931_k127_1319895_35	330214.NIDE3802	1.561e-68	243.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,GGDEF
SRR34280931_k127_1319895_46	929703.KE386491_gene3992	1.784e-23	109.0	COG1044@1|root,COG1044@2|Bacteria,4NT1W@976|Bacteroidetes,47RE1@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1319895_11	330214.NIDE3796	2.75e-183	576.0	COG0500@1|root,COG2226@2|Bacteria,3J1C8@40117|Nitrospirae	2|Bacteria	H	Dimerisation domain	-	-	2.1.1.302	ko:K21377	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
SRR34280931_k127_1319895_21	330214.NIDE3794	1.858e-125	411.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_1319895_4	330214.NIDE3793	9.97e-267	826.0	29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1319895_18	330214.NIDE3791	3.183e-135	435.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K16129	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR34280931_k127_1319895_55	880072.Desac_0525	6.796e-06	55.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,2MSI1@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
SRR34280931_k127_1319895_19	330214.NIDE3790	1.86e-132	425.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	ygdQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TerC
SRR34280931_k127_1319895_14	330214.NIDE3787	1.98e-160	509.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	CBS,Ion_trans_2
SRR34280931_k127_1319895_0	330214.NIDE3786	0.0	1587.0	COG0474@1|root,COG0474@2|Bacteria,3J0WH@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR34280931_k127_1319895_48	638303.Thal_1063	4.158e-12	77.0	COG0589@1|root,COG0589@2|Bacteria,2G4D6@200783|Aquificae	200783|Aquificae	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_1319895_39	330214.NIDE3783	4.308e-58	205.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,GGDEF
SRR34280931_k127_1319895_34	330214.NIDE3782	1.924e-75	255.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,GGDEF
SRR34280931_k127_1319895_58	1316936.K678_07732	0.0002559	46.0	COG2202@1|root,COG4251@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2TSY5@28211|Alphaproteobacteria,2JU4H@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PHY
SRR34280931_k127_1319895_8	330214.NIDE3781	6.84e-203	638.0	COG0477@1|root,COG2814@2|Bacteria,3J0VR@40117|Nitrospirae	40117|Nitrospirae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR34280931_k127_1319895_6	330214.NIDE3778	4.925e-234	734.0	COG1357@1|root,COG1357@2|Bacteria,3J1CA@40117|Nitrospirae	40117|Nitrospirae	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR34280931_k127_1319895_7	330214.NIDE3777	2.339e-219	691.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
SRR34280931_k127_1319895_30	330214.NIDE3776	4.178e-86	288.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000,ko01001	-	-	iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Isochorismatase
SRR34280931_k127_1319895_41	330214.NIDE3775	8.425e-54	194.0	COG2010@1|root,COG2010@2|Bacteria,3J1AX@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
SRR34280931_k127_1319895_15	330214.NIDE3773	2.36e-147	468.0	COG1067@1|root,COG1067@2|Bacteria,3J0X2@40117|Nitrospirae	40117|Nitrospirae	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
SRR34280931_k127_1323901_5	330214.NIDE2365	1.169e-160	508.0	COG1352@1|root,COG1352@2|Bacteria,3J0XI@40117|Nitrospirae	2|Bacteria	NT	Chemotaxis protein methyltransferase	cheR	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR34280931_k127_1323901_7	330214.NIDE2366	8.809e-123	396.0	COG1871@1|root,COG1871@2|Bacteria	2|Bacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.1.1.61,3.5.1.44	ko:K03411,ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheD
SRR34280931_k127_1323901_3	330214.NIDE2367	9.682e-198	619.0	COG2201@1|root,COG2201@2|Bacteria,3J0X3@40117|Nitrospirae	2|Bacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR34280931_k127_1323901_11	330214.NIDE2368	4.454e-46	168.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,STAS,STAS_2
SRR34280931_k127_1323901_10	330214.NIDE2369	5.053e-50	179.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	IV02_16530	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
SRR34280931_k127_1323901_2	330214.NIDE2370	8.075e-211	661.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
SRR34280931_k127_1323901_12	330214.NIDE2371	8.159e-42	158.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt,Response_reg
SRR34280931_k127_1323901_6	330214.NIDE2372	1.606e-129	419.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	cpaE	-	2.7.11.1,2.7.13.3	ko:K02282,ko:K02482,ko:K04757,ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044,ko03021	-	-	-	HATPase_c,HATPase_c_2,HTH_18,HisKA,Response_reg
SRR34280931_k127_1323901_1	330214.NIDE2377	5.8e-217	676.0	COG0381@1|root,COG0381@2|Bacteria,3J148@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR34280931_k127_1323901_0	330214.NIDE2386	0.0	1113.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SRR34280931_k127_1323901_4	330214.NIDE3012	6.679e-180	569.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR34280931_k127_1323901_15	358681.BBR47_17520	1.059e-07	57.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,4HBXU@91061|Bacilli,26R1Z@186822|Paenibacillaceae	91061|Bacilli	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_1323901_16	533240.CRC_01092	1.091e-05	48.0	COG0451@1|root,COG0451@2|Bacteria,1G02N@1117|Cyanobacteria,1HKM7@1161|Nostocales	1117|Cyanobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_1323901_14	56110.Oscil6304_1098	5.06e-18	86.0	COG0451@1|root,COG0451@2|Bacteria,1G02N@1117|Cyanobacteria,1H7SE@1150|Oscillatoriales	1117|Cyanobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_1323901_9	335543.Sfum_0979	2.06e-60	216.0	COG1596@1|root,COG1596@2|Bacteria,1RDXY@1224|Proteobacteria,43DN5@68525|delta/epsilon subdivisions,2X6GD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
SRR34280931_k127_1323901_8	338966.Ppro_2880	4.795e-105	358.0	COG3206@1|root,COG3206@2|Bacteria,1R7T2@1224|Proteobacteria,42S8V@68525|delta/epsilon subdivisions,2WNVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
SRR34280931_k127_1351643_27	330214.NIDE1191	1.396e-45	173.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
SRR34280931_k127_1351643_18	330214.NIDE1193	2.925e-136	437.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Hydrolase_4
SRR34280931_k127_1351643_13	330214.NIDE1195	6.98e-152	482.0	COG0351@1|root,COG0351@2|Bacteria,3J0RM@40117|Nitrospirae	40117|Nitrospirae	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR34280931_k127_1351643_15	330214.NIDE1198	3.132e-143	462.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
SRR34280931_k127_1351643_21	118166.JH976537_gene2419	1.957e-96	323.0	28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1351643_17	330214.NIDE1200	1.251e-142	452.0	COG0819@1|root,COG0819@2|Bacteria	2|Bacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
SRR34280931_k127_1351643_3	330214.NIDE1201	8.372e-285	877.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.6.1.1,1.8.1.4	ko:K00322,ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map00760,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00112,R00209,R01221,R01698,R03815,R07618,R08549	RC00001,RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR34280931_k127_1351643_19	330214.NIDE1202	4.141e-119	389.0	COG2077@1|root,COG2077@2|Bacteria	2|Bacteria	O	thioredoxin peroxidase activity	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
SRR34280931_k127_1351643_9	330214.NIDE1203	7.062e-179	563.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR34280931_k127_1351643_1	330214.NIDE1204	0.0	1204.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,3J10I@40117|Nitrospirae	40117|Nitrospirae	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR34280931_k127_1351643_2	330214.NIDE1205	6.86e-302	928.0	COG0439@1|root,COG0439@2|Bacteria,3J0YP@40117|Nitrospirae	40117|Nitrospirae	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR34280931_k127_1351643_14	330214.NIDE1207	1.089e-147	472.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR34280931_k127_1351643_26	330214.NIDE1208	3.464e-54	195.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR34280931_k127_1351643_16	330214.NIDE1211	1.106e-142	463.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yedA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR34280931_k127_1351643_6	330214.NIDE1213	6.698e-217	676.0	COG1398@1|root,COG1398@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR34280931_k127_1351643_7	330214.NIDE1215	1.442e-216	673.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR34280931_k127_1351643_10	330214.NIDE1216	4.341e-168	531.0	COG0276@1|root,COG0276@2|Bacteria,3J0P9@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR34280931_k127_1351643_4	330214.NIDE1217	1.156e-282	873.0	COG1232@1|root,COG1232@2|Bacteria,3J0PQ@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR34280931_k127_1351643_12	330214.NIDE1220	4.296e-156	496.0	COG1694@1|root,COG3956@2|Bacteria,3J0Q7@40117|Nitrospirae	40117|Nitrospirae	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
SRR34280931_k127_1351643_24	330214.NIDE1221	5.462e-68	233.0	2EAFJ@1|root,334IY@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR34280931_k127_1351643_0	330214.NIDE1222	0.0	1457.0	COG5000@1|root,COG5000@2|Bacteria,3J0B7@40117|Nitrospirae	40117|Nitrospirae	T	GHKL domain	-	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS
SRR34280931_k127_1351643_5	330214.NIDE1223	1.562e-272	842.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1351643_30	580331.Thit_2185	1.021e-16	87.0	2E50I@1|root,32ZU1@2|Bacteria,1VK3E@1239|Firmicutes,24R19@186801|Clostridia,42I9U@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1366302_1	330214.NIDE1294	7.326e-210	652.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR34280931_k127_1366302_8	330214.NIDE1295	2.71e-25	106.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR34280931_k127_1366302_7	330214.NIDE1298	1.005e-28	116.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR34280931_k127_1366302_4	330214.NIDE1299	4.991e-112	362.0	COG0250@1|root,COG0250@2|Bacteria,3J0JA@40117|Nitrospirae	40117|Nitrospirae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR34280931_k127_1366302_6	330214.NIDE1300	2.848e-83	276.0	COG0080@1|root,COG0080@2|Bacteria,3J0K2@40117|Nitrospirae	40117|Nitrospirae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR34280931_k127_1366302_3	330214.NIDE1301	5.32e-140	445.0	COG0081@1|root,COG0081@2|Bacteria,3J0GB@40117|Nitrospirae	40117|Nitrospirae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR34280931_k127_1366302_2	330214.NIDE1302	8.111e-178	560.0	COG0222@1|root,COG0244@1|root,COG0222@2|Bacteria,COG0244@2|Bacteria,3J0NQ@40117|Nitrospirae	40117|Nitrospirae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR34280931_k127_1366302_0	330214.NIDE1303	0.0	2567.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR34280931_k127_1366302_5	330214.NIDE1304	1.462e-108	352.0	COG0086@1|root,COG0086@2|Bacteria,3J0BT@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR34280931_k127_1368108_13	330214.NIDE3237	3.331e-88	293.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4	ko:K00370,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR34280931_k127_1368108_4	330214.NIDE3238	4.86e-291	898.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,3J1FR@40117|Nitrospirae	2|Bacteria	KT	Evidence 2b Function of strongly homologous gene	fhlA	-	-	ko:K02584,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS,PAS_3,PAS_4,PAS_9,Sigma54_activat
SRR34280931_k127_1368108_6	330214.NIDE3239	1.459e-268	834.0	COG1566@1|root,COG1566@2|Bacteria,3J0NN@40117|Nitrospirae	40117|Nitrospirae	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	HlyD_D23
SRR34280931_k127_1368108_3	330214.NIDE3240	5.452e-306	940.0	COG1538@1|root,COG1538@2|Bacteria,3J0N2@40117|Nitrospirae	2|Bacteria	M	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR34280931_k127_1368108_2	330214.NIDE3241	0.0	998.0	COG0477@1|root,COG2814@2|Bacteria,3J0PC@40117|Nitrospirae	40117|Nitrospirae	U	Major Facilitator Superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRR34280931_k127_1368108_10	330214.NIDE3242	8.115e-157	498.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K02598,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.3	-	-	Form_Nir_trans
SRR34280931_k127_1368108_1	330214.NIDE3244	0.0	1122.0	COG4191@1|root,COG5278@1|root,COG4191@2|Bacteria,COG5278@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	fleS	-	2.7.13.3	ko:K02668,ko:K07710,ko:K07711,ko:K10942	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00500,M00501,M00502,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE3,GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR34280931_k127_1368108_14	1283300.ATXB01000001_gene1579	4.714e-82	293.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XE5A@135618|Methylococcales	135618|Methylococcales	T	SMART Signal transduction response regulator, receiver region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1368108_9	330214.NIDE3246	1.393e-163	522.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
SRR34280931_k127_1368108_11	330214.NIDE3247	1.507e-120	391.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_1368108_7	330214.NIDE3249	1.886e-218	687.0	COG1538@1|root,COG1538@2|Bacteria,3J1F2@40117|Nitrospirae	40117|Nitrospirae	MU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR34280931_k127_1368108_8	330214.NIDE3250	5.151e-211	661.0	COG0845@1|root,COG0845@2|Bacteria,3J15V@40117|Nitrospirae	2|Bacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	cusB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR34280931_k127_1368108_0	330214.NIDE3251	0.0	1795.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR34280931_k127_1368108_15	330214.NIDE3252	4.27e-48	173.0	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR34280931_k127_1368108_16	330214.NIDE3253	0.0009015	46.0	COG0387@1|root,COG0387@2|Bacteria	2|Bacteria	P	calcium:proton antiporter activity	chaA	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iB21_1397.B21_01204,iEC55989_1330.EC55989_1314,iECBD_1354.ECBD_2403,iECB_1328.ECB_01194,iECD_1391.ECD_01194,iECIAI1_1343.ECIAI1_1238,iECO103_1326.ECO103_1321,iECO111_1330.ECO111_1548,iECO26_1355.ECO26_1732,iECSE_1348.ECSE_1269,iECW_1372.ECW_m1308,iETEC_1333.ETEC_1322,iEcE24377_1341.EcE24377A_1366,iEcHS_1320.EcHS_A1324,iEcolC_1368.EcolC_2407,iSSON_1240.SSON_1961,iSbBS512_1146.SbBS512_E1383,iUMNK88_1353.UMNK88_1535,iWFL_1372.ECW_m1308	Na_Ca_ex
SRR34280931_k127_1368108_5	330214.NIDE3254	2.553e-287	885.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1368108_12	330214.NIDE3255	4.731e-93	305.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4	ko:K00370,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR34280931_k127_1370481_16	330214.NIDE2956	4.714e-81	295.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_13,AAA_23,Kelch_1,Kelch_4,Peptidase_C14,Tubulin_2,WD40
SRR34280931_k127_1370481_0	330214.NIDE2953	0.0	1420.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2
SRR34280931_k127_1370481_25	330214.NIDE2946	1.066e-22	100.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Y1_Tnp
SRR34280931_k127_1370481_7	118168.MC7420_8133	2.267e-276	861.0	COG3387@1|root,COG3387@2|Bacteria,1G3VS@1117|Cyanobacteria,1H860@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR34280931_k127_1370481_22	2002.JOEQ01000042_gene5915	1.397e-45	175.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria,4EIUM@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_C_6,TetR_N
SRR34280931_k127_1370481_24	497964.CfE428DRAFT_0698	5.272e-40	153.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRR34280931_k127_1370481_14	330214.NIDE2934	3.155e-111	361.0	COG0671@1|root,COG0671@2|Bacteria,3J155@40117|Nitrospirae	40117|Nitrospirae	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,PMT_2
SRR34280931_k127_1370481_11	330214.NIDE2933	1.762e-189	595.0	COG0523@1|root,COG0523@2|Bacteria	2|Bacteria	P	cobalamin synthesis protein	COBW1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR34280931_k127_1370481_9	330214.NIDE2930	2.904e-192	602.0	COG1230@1|root,COG1230@2|Bacteria,3J11Z@40117|Nitrospirae	40117|Nitrospirae	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR34280931_k127_1370481_3	330214.NIDE2929	0.0	1092.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	2|Bacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	3.4.21.53	ko:K03798,ko:K04076,ko:K13525,ko:K17681	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03029,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,FtsH_ext,Peptidase_M41
SRR34280931_k127_1370481_12	330214.NIDE2928	2.965e-162	518.0	2CHNQ@1|root,2Z7KM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1370481_2	330214.NIDE2927	0.0	1149.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3J0AI@40117|Nitrospirae	40117|Nitrospirae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR34280931_k127_1370481_10	330214.NIDE2926	1.304e-189	596.0	COG2812@1|root,COG2812@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR34280931_k127_1370481_21	644801.Psest_1693	8.773e-54	199.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1Z2FW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
SRR34280931_k127_1370481_13	330214.NIDE2923	8.588e-140	446.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SRR34280931_k127_1370481_5	330214.NIDE2922	9.081e-294	908.0	COG1207@1|root,COG1207@2|Bacteria,3J0CG@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
SRR34280931_k127_1370481_1	330214.NIDE2921	0.0	1192.0	COG0449@1|root,COG0449@2|Bacteria,3J0CP@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR34280931_k127_1370481_23	330214.NIDE2920	9.719e-45	166.0	COG0721@1|root,COG0721@2|Bacteria,3J0V3@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR34280931_k127_1370481_18	330214.NIDE2919	1.865e-67	231.0	COG0853@1|root,COG0853@2|Bacteria,3J0Q2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR34280931_k127_1370481_4	330214.NIDE2918	7.234e-298	916.0	COG0154@1|root,COG0154@2|Bacteria,3J0AA@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR34280931_k127_1370481_19	330214.NIDE2917	1.201e-62	217.0	COG4768@1|root,COG4768@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF948)	WQ51_05790	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR34280931_k127_1370481_6	330214.NIDE2915	3.275e-289	891.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR34280931_k127_1370481_8	330214.NIDE2913	8.067e-268	826.0	COG0148@1|root,COG0148@2|Bacteria,3J0DB@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR34280931_k127_1370481_20	330214.NIDE2912	5.091e-58	204.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR34280931_k127_1370481_15	330214.NIDE2911	3.213e-89	297.0	COG1159@1|root,COG1159@2|Bacteria,3J0IB@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR34280931_k127_1403403_53	330214.NIDE0783	6.378e-113	366.0	COG0193@1|root,COG0193@2|Bacteria,3J0QR@40117|Nitrospirae	40117|Nitrospirae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR34280931_k127_1403403_42	330214.NIDE0782	1.57e-138	443.0	COG1825@1|root,COG1825@2|Bacteria,3J0NK@40117|Nitrospirae	40117|Nitrospirae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR34280931_k127_1403403_25	330214.NIDE0781	3.621e-188	591.0	COG0462@1|root,COG0462@2|Bacteria,3J0D0@40117|Nitrospirae	40117|Nitrospirae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR34280931_k127_1403403_41	330214.NIDE0780	1.421e-141	454.0	COG1947@1|root,COG1947@2|Bacteria,3J0N1@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR34280931_k127_1403403_36	1499967.BAYZ01000027_gene1786	5.182e-155	505.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_1403403_4	330214.NIDE0778	0.0	1032.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR34280931_k127_1403403_13	330214.NIDE0777	1.351e-238	741.0	COG1459@1|root,COG1459@2|Bacteria,3J0HZ@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SRR34280931_k127_1403403_55	330214.NIDE0775	3.693e-98	323.0	COG0558@1|root,COG0558@2|Bacteria,3J183@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR34280931_k127_1403403_32	330214.NIDE0773	5.092e-175	555.0	COG1680@1|root,COG1680@2|Bacteria,3J131@40117|Nitrospirae	40117|Nitrospirae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR34280931_k127_1403403_59	330214.NIDE0772	4.686e-87	289.0	COG3599@1|root,COG3599@2|Bacteria,3J19M@40117|Nitrospirae	40117|Nitrospirae	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR34280931_k127_1403403_71	330214.NIDE0771	1.141e-53	192.0	COG0762@1|root,COG0762@2|Bacteria,3J0U5@40117|Nitrospirae	40117|Nitrospirae	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR34280931_k127_1403403_46	330214.NIDE0770	5.015e-126	409.0	COG0345@1|root,COG0345@2|Bacteria,3J0N8@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR34280931_k127_1403403_49	330214.NIDE0769	1.705e-119	387.0	COG0325@1|root,COG0325@2|Bacteria,3J0RJ@40117|Nitrospirae	40117|Nitrospirae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR34280931_k127_1403403_50	330214.NIDE0768	3.572e-119	390.0	COG1496@1|root,COG1496@2|Bacteria,3J0TC@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR34280931_k127_1403403_12	330214.NIDE0767	3.152e-245	764.0	COG0206@1|root,COG0206@2|Bacteria,3J0D4@40117|Nitrospirae	40117|Nitrospirae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR34280931_k127_1403403_11	330214.NIDE0766	3.074e-262	809.0	COG0849@1|root,COG0849@2|Bacteria,3J0Q3@40117|Nitrospirae	40117|Nitrospirae	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR34280931_k127_1403403_34	330214.NIDE0765	6.814e-162	516.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
SRR34280931_k127_1403403_24	330214.NIDE0764	1.456e-189	594.0	COG1181@1|root,COG1181@2|Bacteria,3J0JM@40117|Nitrospirae	40117|Nitrospirae	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR34280931_k127_1403403_31	330214.NIDE0763	3.258e-176	556.0	COG0812@1|root,COG0812@2|Bacteria,3J0Q1@40117|Nitrospirae	40117|Nitrospirae	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR34280931_k127_1403403_5	330214.NIDE0762	3.316e-290	894.0	COG0773@1|root,COG0773@2|Bacteria,3J0D5@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR34280931_k127_1403403_29	330214.NIDE0761	1.694e-179	592.0	COG0707@1|root,COG0707@2|Bacteria,3J0JS@40117|Nitrospirae	40117|Nitrospirae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR34280931_k127_1403403_20	330214.NIDE0760	4.773e-213	666.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR34280931_k127_1403403_10	330214.NIDE0759	1.931e-266	824.0	COG0771@1|root,COG0771@2|Bacteria,3J0HT@40117|Nitrospirae	40117|Nitrospirae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR34280931_k127_1403403_16	330214.NIDE0758	2.209e-222	691.0	COG0472@1|root,COG0472@2|Bacteria,3J0C4@40117|Nitrospirae	40117|Nitrospirae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR34280931_k127_1403403_6	330214.NIDE0757	8.424e-284	875.0	COG0770@1|root,COG0770@2|Bacteria,3J0PW@40117|Nitrospirae	40117|Nitrospirae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR34280931_k127_1403403_8	330214.NIDE0756	1.917e-273	848.0	COG0769@1|root,COG0769@2|Bacteria,3J0DS@40117|Nitrospirae	40117|Nitrospirae	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR34280931_k127_1403403_3	330214.NIDE0755	0.0	1082.0	COG0768@1|root,COG0768@2|Bacteria,3J0FH@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR34280931_k127_1403403_70	330214.NIDE0754	6.239e-56	197.0	2DT1T@1|root,33IAD@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	FtsL
SRR34280931_k127_1403403_35	330214.NIDE0753	5.208e-157	499.0	COG0275@1|root,COG0275@2|Bacteria,3J0NU@40117|Nitrospirae	40117|Nitrospirae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR34280931_k127_1403403_9	330214.NIDE0751	2.515e-270	833.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR34280931_k127_1403403_23	330214.NIDE0749	7.685e-193	604.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR34280931_k127_1403403_57	330214.NIDE0748	2.271e-90	299.0	COG1666@1|root,COG1666@2|Bacteria,3J135@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR34280931_k127_1403403_1	330214.NIDE0747	0.0	1248.0	COG1966@1|root,COG1966@2|Bacteria,3J10E@40117|Nitrospirae	40117|Nitrospirae	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR34280931_k127_1403403_75	794903.OPIT5_23205	1.113e-42	166.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
SRR34280931_k127_1403403_33	330214.NIDE0745	3.405e-170	540.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR34280931_k127_1403403_43	330214.NIDE0744	5.962e-136	454.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR34280931_k127_1403403_19	330214.NIDE0743	1.137e-213	673.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR34280931_k127_1403403_44	330214.NIDE0742	2.237e-131	425.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	ywdF	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
SRR34280931_k127_1403403_48	330214.NIDE0741	4.916e-120	404.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR34280931_k127_1403403_78	1157490.EL26_06120	9.874e-23	111.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,4HCJ2@91061|Bacilli,2781P@186823|Alicyclobacillaceae	91061|Bacilli	S	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR34280931_k127_1403403_17	330214.NIDE0740	1.94e-218	685.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_1403403_28	330214.NIDE0739	1.89e-180	575.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_1403403_26	330214.NIDE0738	5.255e-184	582.0	COG0463@1|root,COG0463@2|Bacteria,3J13V@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR34280931_k127_1403403_77	314278.NB231_07597	1.049e-25	119.0	COG0392@1|root,COG0392@2|Bacteria,1RCBH@1224|Proteobacteria,1S366@1236|Gammaproteobacteria,1X1IF@135613|Chromatiales	135613|Chromatiales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR34280931_k127_1403403_7	330214.NIDE0736	3.688e-280	867.0	COG0558@1|root,COG1208@1|root,COG0558@2|Bacteria,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR34280931_k127_1403403_38	330214.NIDE0735	3.857e-147	467.0	COG1213@1|root,COG1213@2|Bacteria,3J1BZ@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1403403_21	330214.NIDE0734	1.265e-208	651.0	COG0075@1|root,COG0075@2|Bacteria,3J0FC@40117|Nitrospirae	2|Bacteria	E	Evidence 2b Function of strongly homologous gene	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306,ko:K09469	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
SRR34280931_k127_1403403_54	330214.NIDE0733	8.523e-111	362.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR34280931_k127_1403403_56	330214.NIDE0732	5.545e-94	310.0	COG4032@1|root,COG4032@2|Bacteria	2|Bacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ppd	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR34280931_k127_1403403_74	671143.DAMO_1259	9.935e-45	170.0	COG1309@1|root,COG1309@2|Bacteria,2NQ8G@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	MA20_16815	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR34280931_k127_1403403_15	330214.NIDE0727	2.406e-229	713.0	COG0845@1|root,COG0845@2|Bacteria,3J15F@40117|Nitrospirae	40117|Nitrospirae	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR34280931_k127_1403403_0	330214.NIDE0726	0.0	1935.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR34280931_k127_1403403_68	330214.NIDE0725	4.881e-58	206.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR34280931_k127_1403403_58	330214.NIDE0724	1.802e-89	300.0	COG1586@1|root,COG1586@2|Bacteria	2|Bacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synth
SRR34280931_k127_1403403_47	330214.NIDE0722	2.473e-121	392.0	COG1018@1|root,COG1018@2|Bacteria	330214.NIDE0722|-	C	nitric oxide dioxygenase activity	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	-
SRR34280931_k127_1403403_39	330214.NIDE0721	3.691e-143	455.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	spoIVFB	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
SRR34280931_k127_1403403_37	330214.NIDE0720	2.112e-151	484.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
SRR34280931_k127_1403403_14	330214.NIDE0719	7.606e-231	715.0	28IX1@1|root,2Z8V3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
SRR34280931_k127_1403403_52	330214.NIDE0715	4.21e-113	369.0	2E469@1|root,32Z27@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1403403_27	330214.NIDE0701	2.477e-181	569.0	COG0142@1|root,COG0142@2|Bacteria,3J0H1@40117|Nitrospirae	40117|Nitrospirae	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR34280931_k127_1403403_22	330214.NIDE0700	8.49e-199	622.0	COG0451@1|root,COG0451@2|Bacteria,3J0T9@40117|Nitrospirae	40117|Nitrospirae	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR34280931_k127_1403403_40	330214.NIDE0699	5.245e-143	456.0	COG2324@1|root,COG2324@2|Bacteria,3J195@40117|Nitrospirae	40117|Nitrospirae	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
SRR34280931_k127_1403403_45	330214.NIDE0698	8.773e-128	409.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycA	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	Cytochrom_C,Cytochrome_CBB3
SRR34280931_k127_1403403_63	330214.NIDE0695	1.25e-65	227.0	COG1950@1|root,COG1950@2|Bacteria,3J19X@40117|Nitrospirae	40117|Nitrospirae	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR34280931_k127_1403403_2	330214.NIDE0694	0.0	1119.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,3J117@40117|Nitrospirae	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA
SRR34280931_k127_1403403_62	330214.NIDE0691	1.292e-78	266.0	COG2094@1|root,COG2094@2|Bacteria	2|Bacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR34280931_k127_141368_47	93220.LV28_14490	2.322e-58	213.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VKN4@28216|Betaproteobacteria,1K579@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_141368_62	267608.RSc2707	8.746e-12	65.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VUTU@28216|Betaproteobacteria,1K9RG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_141368_60	93220.LV28_14485	1.639e-14	74.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VUTU@28216|Betaproteobacteria,1K9RG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_141368_36	330214.NIDE2963	1.478e-91	302.0	COG1846@1|root,COG1846@2|Bacteria,3J13N@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR34280931_k127_141368_11	330214.NIDE2964	5.148e-211	662.0	COG0845@1|root,COG0845@2|Bacteria,3J11U@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K19586	-	M00767	-	-	ko00000,ko00002,ko02000	2.A.6.2.47,8.A.1	-	-	HlyD_D23
SRR34280931_k127_141368_0	330214.NIDE2965	0.0	1983.0	COG0841@1|root,COG0841@2|Bacteria,3J0FA@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138,ko:K19585	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00767	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.47	-	-	ACR_tran
SRR34280931_k127_141368_51	330214.NIDE3158	5.736e-46	177.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR34280931_k127_141368_12	857087.Metme_1661	1.328e-207	657.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RQ6V@1236|Gammaproteobacteria,1XDWC@135618|Methylococcales	135618|Methylococcales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR34280931_k127_141368_6	243233.MCA0178	9.994e-245	767.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RQ6V@1236|Gammaproteobacteria,1XDWC@135618|Methylococcales	135618|Methylococcales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR34280931_k127_141368_21	243233.MCA0177	1.113e-150	486.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1S3MR@1236|Gammaproteobacteria,1XEPB@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR34280931_k127_141368_10	243233.MCA0176	3.234e-218	689.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RQ6B@1236|Gammaproteobacteria,1XEVK@135618|Methylococcales	135618|Methylococcales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR34280931_k127_141368_42	1173023.KE650771_gene5116	6.865e-79	302.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_141368_54	643473.KB235930_gene2909	8.936e-39	169.0	COG0642@1|root,COG0784@1|root,COG2197@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HMNI@1161|Nostocales	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_8,Response_reg
SRR34280931_k127_141368_55	1210884.HG799464_gene11082	8.396e-33	150.0	COG5002@1|root,COG5002@2|Bacteria,2J2DJ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR34280931_k127_141368_46	1210884.HG799464_gene11083	4.896e-59	211.0	COG0784@1|root,COG0784@2|Bacteria,2J0IF@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_141368_32	1541065.JRFE01000016_gene508	1.958e-102	347.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,3VJIW@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR34280931_k127_141368_61	595460.RRSWK_03372	2.671e-14	77.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR34280931_k127_141368_53	1123242.JH636435_gene953	3.977e-44	173.0	COG0784@1|root,COG3290@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2J501@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR34280931_k127_141368_58	886293.Sinac_1096	1.208e-19	96.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2461@1|root,COG3290@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG3290@2|Bacteria,2J1UU@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR34280931_k127_141368_63	497964.CfE428DRAFT_1827	1.422e-09	62.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,46US9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR34280931_k127_141368_1	330214.NIDE2967	0.0	1502.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
SRR34280931_k127_141368_8	330214.NIDE2969	1.082e-224	697.0	COG0722@1|root,COG0722@2|Bacteria	2|Bacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934	DAHP_synth_1
SRR34280931_k127_141368_22	330214.NIDE2970	3.129e-148	471.0	COG0084@1|root,COG0084@2|Bacteria,3J0KM@40117|Nitrospirae	40117|Nitrospirae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
SRR34280931_k127_141368_57	56780.SYN_01764	3.27e-25	111.0	COG3688@1|root,COG3688@2|Bacteria,1N1NF@1224|Proteobacteria,42UMH@68525|delta/epsilon subdivisions,2WQJ5@28221|Deltaproteobacteria,2MSA5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
SRR34280931_k127_141368_7	330214.NIDE2972	2.543e-227	710.0	COG0860@1|root,COG0860@2|Bacteria,3J0MT@40117|Nitrospirae	40117|Nitrospirae	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRR34280931_k127_141368_26	330214.NIDE2973	1.338e-129	417.0	COG0101@1|root,COG0101@2|Bacteria,3J0PM@40117|Nitrospirae	40117|Nitrospirae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR34280931_k127_141368_50	330214.NIDE2974	4.328e-49	176.0	2E4IS@1|root,32ZDU@2|Bacteria	2|Bacteria	S	phosphate starvation-inducible protein, PsiF	psiF	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
SRR34280931_k127_141368_28	330214.NIDE2975	1.589e-122	396.0	COG1045@1|root,COG1045@2|Bacteria,3J11G@40117|Nitrospirae	40117|Nitrospirae	E	Serine acetyltransferase, N-terminal	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR34280931_k127_141368_37	330214.NIDE2976	1.452e-90	301.0	COG0245@1|root,COG0245@2|Bacteria,3J0N6@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR34280931_k127_141368_27	330214.NIDE2977	7.567e-126	406.0	COG1211@1|root,COG1211@2|Bacteria,3J18C@40117|Nitrospirae	40117|Nitrospirae	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR34280931_k127_141368_14	330214.NIDE2978	3.962e-202	634.0	COG4956@1|root,COG4956@2|Bacteria,3J0G5@40117|Nitrospirae	40117|Nitrospirae	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR34280931_k127_141368_3	330214.NIDE2979	2.145e-300	925.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR34280931_k127_141368_15	330214.NIDE2980	1.133e-196	614.0	COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae	40117|Nitrospirae	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR34280931_k127_141368_13	330214.NIDE2981	4.242e-207	645.0	COG0158@1|root,COG0158@2|Bacteria,3J12X@40117|Nitrospirae	40117|Nitrospirae	G	Fructose-1-6-bisphosphatase, N-terminal domain	-	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
SRR34280931_k127_141368_25	330214.NIDE2982	5.138e-133	428.0	COG3170@1|root,COG3170@2|Bacteria,3J1DA@40117|Nitrospirae	40117|Nitrospirae	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR34280931_k127_141368_5	330214.NIDE2983	3.752e-287	884.0	COG1109@1|root,COG1109@2|Bacteria,3J0AF@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR34280931_k127_141368_4	330214.NIDE2984	3.253e-288	888.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,3J0FF@40117|Nitrospirae	40117|Nitrospirae	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR34280931_k127_141368_38	330214.NIDE2985	2.423e-87	291.0	COG1778@1|root,COG1778@2|Bacteria,3J1EJ@40117|Nitrospirae	40117|Nitrospirae	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
SRR34280931_k127_141368_2	330214.NIDE2986	2.051e-301	925.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRR34280931_k127_141368_9	330214.NIDE2987	4.311e-219	682.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_141368_31	1321781.HMPREF1985_01945	1.813e-102	347.0	COG0438@1|root,COG0438@2|Bacteria,1V4WG@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_141368_44	671143.DAMO_0905	3.077e-73	258.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_141368_39	1403819.BATR01000181_gene6068	1.286e-85	298.0	COG1442@1|root,COG1442@2|Bacteria,46VJK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_141368_29	1123072.AUDH01000008_gene194	2.007e-111	371.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQZ9@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_141368_23	1192124.LIG30_2204	6.258e-136	447.0	COG0457@1|root,COG2519@1|root,COG0457@2|Bacteria,COG2519@2|Bacteria,1NBJD@1224|Proteobacteria	1224|Proteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR34280931_k127_141368_20	324602.Caur_1218	2.574e-152	489.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi,375A6@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR34280931_k127_141368_48	102232.GLO73106DRAFT_00009580	6.633e-56	208.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR34280931_k127_141368_30	452637.Oter_1769	7.711e-105	363.0	COG1216@1|root,COG1216@2|Bacteria,46V89@74201|Verrucomicrobia,3K8DQ@414999|Opitutae	414999|Opitutae	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_141368_34	1183438.GKIL_2400	1.772e-95	325.0	COG0438@1|root,COG0438@2|Bacteria,1G1FI@1117|Cyanobacteria	1117|Cyanobacteria	M	Exostosin family	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin
SRR34280931_k127_141368_49	504472.Slin_2583	5.039e-51	193.0	COG1215@1|root,COG1215@2|Bacteria,4PME9@976|Bacteroidetes,47JUK@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_141368_41	1197906.CAJQ02000023_gene2178	4.561e-80	290.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_141368_56	1380391.JIAS01000014_gene1963	8.58e-32	138.0	28NSU@1|root,2ZBRQ@2|Bacteria,1R0G0@1224|Proteobacteria,2TYR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR34280931_k127_141368_59	323098.Nwi_2399	2.575e-16	92.0	2F9SE@1|root,3422C@2|Bacteria,1RKAM@1224|Proteobacteria,2UBM4@28211|Alphaproteobacteria,3JZXN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_141368_19	1144319.PMI16_02476	4.249e-154	506.0	COG0438@1|root,COG0438@2|Bacteria,1P06I@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_141368_16	335541.Swol_0210	8.862e-161	512.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR34280931_k127_141368_45	335541.Swol_0211	2.57e-72	250.0	COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,24FCK@186801|Clostridia	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR34280931_k127_141368_40	546271.Selsp_0060	3.26e-80	273.0	COG0223@1|root,COG0223@2|Bacteria,1V49K@1239|Firmicutes	1239|Firmicutes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
SRR34280931_k127_141368_24	1163617.SCD_n02902	2.384e-133	447.0	COG0223@1|root,COG1670@1|root,COG3980@1|root,COG0223@2|Bacteria,COG1670@2|Bacteria,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,2VMJW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3980 Spore coat polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyco_tran_28_C
SRR34280931_k127_141368_33	1037409.BJ6T_37170	2.117e-99	329.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,3K0M9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR34280931_k127_141368_18	269799.Gmet_0457	2.564e-157	504.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,43UD7@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_141368_17	1009370.ALO_18967	6.965e-159	506.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,4H35J@909932|Negativicutes	909932|Negativicutes	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
SRR34280931_k127_141368_35	330214.NIDE3011	9.809e-94	308.0	COG0451@1|root,COG0451@2|Bacteria,3J0XH@40117|Nitrospirae	40117|Nitrospirae	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_1419391_6	330214.NIDE2040	4.454e-298	917.0	COG0147@1|root,COG0147@2|Bacteria,3J0FG@40117|Nitrospirae	40117|Nitrospirae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR34280931_k127_1419391_28	330214.NIDE2041	1.707e-115	373.0	COG0512@1|root,COG0512@2|Bacteria,3J0H8@40117|Nitrospirae	40117|Nitrospirae	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR34280931_k127_1419391_14	330214.NIDE2042	6.433e-196	617.0	COG0547@1|root,COG0547@2|Bacteria,3J0HE@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR34280931_k127_1419391_17	330214.NIDE2043	2.037e-155	493.0	COG0134@1|root,COG0134@2|Bacteria,3J0NT@40117|Nitrospirae	40117|Nitrospirae	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR34280931_k127_1419391_29	330214.NIDE2045	6.088e-113	366.0	COG0135@1|root,COG0135@2|Bacteria,3J0SA@40117|Nitrospirae	40117|Nitrospirae	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR34280931_k127_1419391_9	330214.NIDE2046	3.82e-250	774.0	COG0133@1|root,COG0133@2|Bacteria,3J0E1@40117|Nitrospirae	40117|Nitrospirae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_1419391_20	330214.NIDE2047	8.221e-149	473.0	COG0159@1|root,COG0159@2|Bacteria,3J0ME@40117|Nitrospirae	40117|Nitrospirae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR34280931_k127_1419391_16	330214.NIDE2048	9.362e-165	526.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_30	330214.NIDE2049	3.741e-110	359.0	2FJ9R@1|root,34AZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_12	330214.NIDE2050	1.448e-222	693.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
SRR34280931_k127_1419391_24	330214.NIDE2051	1.092e-131	421.0	COG1136@1|root,COG1136@2|Bacteria,3J0IT@40117|Nitrospirae	40117|Nitrospirae	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR34280931_k127_1419391_8	330214.NIDE2052	1.343e-254	787.0	COG4591@1|root,COG4591@2|Bacteria,3J0EF@40117|Nitrospirae	40117|Nitrospirae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR34280931_k127_1419391_4	330214.NIDE2053	1.016e-314	966.0	COG1190@1|root,COG1190@2|Bacteria,3J0AW@40117|Nitrospirae	40117|Nitrospirae	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR34280931_k127_1419391_13	330214.NIDE2054	1.377e-220	685.0	COG1186@1|root,COG1186@2|Bacteria,3J0EX@40117|Nitrospirae	40117|Nitrospirae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR34280931_k127_1419391_3	330214.NIDE2055	0.0	1027.0	COG0815@1|root,COG0815@2|Bacteria,3J0HA@40117|Nitrospirae	40117|Nitrospirae	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR34280931_k127_1419391_39	330214.NIDE2061	1.147e-75	256.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
SRR34280931_k127_1419391_40	330214.NIDE2063	9.129e-70	238.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	osmE	GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896	-	ko:K04064,ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	OmpA,SmpA_OmlA
SRR34280931_k127_1419391_35	330214.NIDE2064	1.178e-92	308.0	2ATAH@1|root,31ITJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_37	330214.NIDE2065	5.418e-79	265.0	2B047@1|root,31SEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_34	330214.NIDE2066	2.602e-99	326.0	2B047@1|root,31SEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_25	330214.NIDE2067	7.92e-126	406.0	COG3751@1|root,COG3751@2|Bacteria	2|Bacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
SRR34280931_k127_1419391_58	330214.NIDE2068	5.176e-33	132.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR34280931_k127_1419391_61	330214.NIDE2069	1.583e-26	111.0	arCOG12353@1|root,33KP1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419391_10	330214.NIDE2070	3.836e-236	743.0	COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,GGDEF,HATPase_c_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
SRR34280931_k127_1419391_2	330214.NIDE2073	0.0	1113.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
SRR34280931_k127_1419391_11	330214.NIDE2074	1.262e-235	730.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
SRR34280931_k127_1419391_26	1121127.JAFA01000027_gene88	8.371e-123	407.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VIYI@28216|Betaproteobacteria,1KH1C@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR34280931_k127_1419391_31	269482.Bcep1808_1862	3.243e-108	363.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria,1K2D3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Twin-arginine translocation pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
SRR34280931_k127_1419391_57	593117.TGAM_2148	3.5e-33	144.0	COG0463@1|root,arCOG01381@2157|Archaea,2XVM0@28890|Euryarchaeota,243JM@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_1419391_51	272134.KB731324_gene3575	3.702e-50	194.0	COG3000@1|root,COG3000@2|Bacteria,1GAN0@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR34280931_k127_1419391_62	930169.B5T_03476	5.249e-17	82.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,1XMI5@135619|Oceanospirillales	135619|Oceanospirillales	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
SRR34280931_k127_1419391_27	330214.NIDE2082	7.796e-119	385.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,CHAP,NLPC_P60
SRR34280931_k127_1419391_5	330214.NIDE2083	6.57e-312	960.0	COG0033@1|root,COG0033@2|Bacteria,3J1FS@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR34280931_k127_1419391_48	330214.NIDE2084	4.336e-51	183.0	COG0526@1|root,COG0526@2|Bacteria,3J1BP@40117|Nitrospirae	40117|Nitrospirae	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR34280931_k127_1419391_32	247490.KSU1_D0161	2.253e-102	370.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR34280931_k127_1419391_0	330214.NIDE2086	0.0	1710.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR34280931_k127_1419391_43	330214.NIDE2087	1.011e-60	212.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
SRR34280931_k127_1419391_15	330214.NIDE2088	3.268e-172	541.0	COG0682@1|root,COG0682@2|Bacteria,3J0G4@40117|Nitrospirae	40117|Nitrospirae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR34280931_k127_1419391_56	330214.NIDE2089	6.99e-37	142.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR34280931_k127_1419391_41	330214.NIDE2253	1.482e-62	219.0	COG2363@1|root,COG2363@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ygdD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF423
SRR34280931_k127_1419391_19	330214.NIDE2255	1.779e-154	490.0	COG0412@1|root,COG0412@2|Bacteria,3J1B9@40117|Nitrospirae	40117|Nitrospirae	Q	Alpha/beta hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR34280931_k127_1419391_18	330214.NIDE2257	3.423e-155	496.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR34280931_k127_1419391_54	330214.NIDE2258	8.632e-40	148.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR34280931_k127_1419391_7	330214.NIDE2260	1.714e-295	911.0	COG0606@1|root,COG0606@2|Bacteria,3J0ZK@40117|Nitrospirae	40117|Nitrospirae	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR34280931_k127_1419391_1	330214.NIDE2263	0.0	1607.0	COG0542@1|root,COG0542@2|Bacteria,3J0AV@40117|Nitrospirae	40117|Nitrospirae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR34280931_k127_1419391_65	330214.NIDE2265	0.0003037	48.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR34280931_k127_1419448_10	330214.NIDE1930	1.163e-69	239.0	COG1905@1|root,COG1905@2|Bacteria,3J1BD@40117|Nitrospirae	40117|Nitrospirae	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR34280931_k127_1419448_3	330214.NIDE1931	2.495e-297	916.0	COG1894@1|root,COG1894@2|Bacteria,3J0WX@40117|Nitrospirae	40117|Nitrospirae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
SRR34280931_k127_1419448_1	330214.NIDE1932	0.0	1614.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	40117|Nitrospirae	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR34280931_k127_1419448_6	330214.NIDE1933	5.403e-145	464.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K02598,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.3	-	-	Form_Nir_trans
SRR34280931_k127_1419448_4	330214.NIDE1934	1.351e-238	741.0	COG0477@1|root,COG2814@2|Bacteria,3J0ZP@40117|Nitrospirae	40117|Nitrospirae	EGP	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR34280931_k127_1419448_15	227377.CBU_0007a	3.457e-34	133.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR34280931_k127_1419448_16	96561.Dole_0659	1.087e-24	104.0	COG3514@1|root,COG3514@2|Bacteria,1PWSE@1224|Proteobacteria,43A9S@68525|delta/epsilon subdivisions,2WTC0@28221|Deltaproteobacteria,2MP7T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419448_0	330214.NIDE1937	0.0	2333.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SRR34280931_k127_1419448_17	316067.Geob_2599	9.625e-10	63.0	COG2982@1|root,COG2982@2|Bacteria,1PJZH@1224|Proteobacteria,42XG1@68525|delta/epsilon subdivisions,2WTDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
SRR34280931_k127_1419448_14	330214.NIDE2032	6.293e-44	162.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR34280931_k127_1419448_8	330214.NIDE2033	7.341e-77	258.0	COG4747@1|root,COG4747@2|Bacteria,3J1DW@40117|Nitrospirae	40117|Nitrospirae	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SRR34280931_k127_1419448_7	330214.NIDE2034	2.36e-137	442.0	COG0797@1|root,COG0797@2|Bacteria,3J0PD@40117|Nitrospirae	40117|Nitrospirae	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR34280931_k127_1419448_9	926561.KB900617_gene1766	1.189e-76	274.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR34280931_k127_1419448_2	330214.NIDE2036	0.0	1177.0	COG0272@1|root,COG0272@2|Bacteria,3J0W8@40117|Nitrospirae	40117|Nitrospirae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR34280931_k127_1419954_10	330214.NIDE4356	2.925e-71	244.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT,TrbL,VanY
SRR34280931_k127_1419954_1	330214.NIDE4355	2.185e-230	719.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_1419954_3	1502852.FG94_00148	7.013e-192	608.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2WENQ@28216|Betaproteobacteria,472E8@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR34280931_k127_1419954_14	1166948.JPZL01000001_gene2565	5.182e-22	111.0	2E7F7@1|root,331Y7@2|Bacteria,1N99B@1224|Proteobacteria,1SVUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1419954_16	1121413.JMKT01000011_gene2409	2.605e-10	74.0	COG0457@1|root,COG0457@2|Bacteria,1N336@1224|Proteobacteria,42UTQ@68525|delta/epsilon subdivisions,2WQW8@28221|Deltaproteobacteria,2MCP0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR34280931_k127_1419954_11	335541.Swol_2440	9.247e-49	188.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
SRR34280931_k127_1419954_12	365046.Rta_23320	2.424e-38	148.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,4AEF6@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_1419954_15	1304885.AUEY01000035_gene2228	1.449e-14	79.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WJUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRR34280931_k127_1419954_13	56780.SYN_00226	8.618e-37	146.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_1419954_5	330214.NIDE4352	5.065e-132	427.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR34280931_k127_1419954_6	330214.NIDE4351	1.807e-126	409.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4170,Inositol_P
SRR34280931_k127_1419954_2	330214.NIDE4350	1.518e-221	688.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR34280931_k127_1419954_7	330214.NIDE4348	3.707e-124	400.0	COG0066@1|root,COG0066@2|Bacteria,3J10U@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR34280931_k127_1419954_0	330214.NIDE4347	1.25e-273	842.0	COG0065@1|root,COG0065@2|Bacteria,3J0IH@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR34280931_k127_1443480_7	330214.NIDE2319	4.078e-258	801.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,3J0M9@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar basal body rod FlgEFG protein C-terminal	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR34280931_k127_1443480_19	330214.NIDE2320	1.576e-160	509.0	COG1344@1|root,COG1344@2|Bacteria,3J0VI@40117|Nitrospirae	40117|Nitrospirae	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
SRR34280931_k127_1443480_31	330214.NIDE2321	2.365e-46	168.0	COG1551@1|root,COG1551@2|Bacteria	2|Bacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563,ko:K13626	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02035,ko03019	-	-	-	CsrA
SRR34280931_k127_1443480_27	330214.NIDE2322	3.411e-81	272.0	COG1699@1|root,COG1699@2|Bacteria,3J0V2@40117|Nitrospirae	40117|Nitrospirae	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
SRR34280931_k127_1443480_1	330214.NIDE2323	0.0	1488.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE8,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_1443480_14	330214.NIDE2324	3.409e-197	622.0	COG2206@1|root,COG2206@2|Bacteria,3J14V@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
SRR34280931_k127_1443480_23	330214.NIDE2325	1.082e-118	385.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
SRR34280931_k127_1443480_8	330214.NIDE2326	1.069e-249	773.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_1443480_15	330214.NIDE2327	5.542e-196	612.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR34280931_k127_1443480_12	330214.NIDE2328	7.094e-210	655.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	lmbP	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR34280931_k127_1443480_22	330214.NIDE2329	1.85e-128	420.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.71,3.1.3.82,3.1.3.83	ko:K03273,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771,R09772	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like,NTP_transferase
SRR34280931_k127_1443480_16	330214.NIDE2330	1.232e-189	600.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_1443480_5	330214.NIDE2331	1.569e-304	938.0	COG1032@1|root,COG1032@2|Bacteria,3J16J@40117|Nitrospirae	40117|Nitrospirae	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_1443480_2	330214.NIDE2332	0.0	1199.0	COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae	2|Bacteria	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR34280931_k127_1443480_3	330214.NIDE2333	0.0	1045.0	COG1032@1|root,COG1032@2|Bacteria,3J16J@40117|Nitrospirae	40117|Nitrospirae	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_1443480_0	330214.NIDE2334	0.0	2481.0	COG0438@1|root,COG1215@1|root,COG1216@1|root,COG2227@1|root,COG3118@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	celD	-	-	ko:K02453,ko:K07280,ko:K20444,ko:K20543	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000,ko02044	1.B.55.3,3.A.15,4.D.1.3	GT2,GT4	-	BCSC_C,Glyco_transf_41,Glycos_transf_2,TPR_16,TPR_19,TPR_8
SRR34280931_k127_1443480_34	330214.NIDE2337	4.518e-26	122.0	COG0859@1|root,COG0859@2|Bacteria,3J197@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR34280931_k127_1443480_4	330214.NIDE2336	0.0	1002.0	COG4641@1|root,COG4641@2|Bacteria,3J0ZZ@40117|Nitrospirae	40117|Nitrospirae	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
SRR34280931_k127_1443480_6	330214.NIDE2337	1.352e-297	919.0	COG0859@1|root,COG0859@2|Bacteria,3J197@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR34280931_k127_1443480_21	330214.NIDE2339	2.141e-149	475.0	COG1344@1|root,COG1344@2|Bacteria,3J0UP@40117|Nitrospirae	40117|Nitrospirae	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
SRR34280931_k127_1443480_30	330214.NIDE2340	1.443e-51	184.0	COG1334@1|root,COG1334@2|Bacteria	2|Bacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
SRR34280931_k127_1443480_10	330214.NIDE2341	7.198e-228	713.0	COG1345@1|root,COG1345@2|Bacteria,3J0S1@40117|Nitrospirae	40117|Nitrospirae	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
SRR34280931_k127_1443480_28	330214.NIDE2342	7.447e-76	255.0	COG1516@1|root,COG1516@2|Bacteria,3J1A2@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
SRR34280931_k127_1443480_18	330214.NIDE2345	6.926e-164	520.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	ylxH-3	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
SRR34280931_k127_1443480_33	330214.NIDE2346	1.178e-30	123.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
SRR34280931_k127_1443480_17	330214.NIDE2347	1.581e-173	546.0	COG1352@1|root,COG1352@2|Bacteria,3J0XI@40117|Nitrospirae	40117|Nitrospirae	NT	Chemotaxis protein methyltransferase	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR34280931_k127_1443480_29	330214.NIDE2348	2.937e-69	235.0	COG0745@1|root,COG0745@2|Bacteria,3J1FT@40117|Nitrospirae	40117|Nitrospirae	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR34280931_k127_1443480_25	330214.NIDE2349	4.628e-102	335.0	COG3143@1|root,COG3143@2|Bacteria,3J1AW@40117|Nitrospirae	40117|Nitrospirae	NT	Chemotaxis phosphatase, CheZ	-	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
SRR34280931_k127_1443480_20	653733.Selin_1355	3.325e-160	525.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR34280931_k127_1443480_13	330214.NIDE2351	1.766e-197	617.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,3J14W@40117|Nitrospirae	40117|Nitrospirae	T	Two component signalling adaptor domain	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
SRR34280931_k127_1443480_11	330214.NIDE2352	9.607e-217	676.0	COG2201@1|root,COG2201@2|Bacteria,3J0X3@40117|Nitrospirae	40117|Nitrospirae	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR34280931_k127_1443480_9	330214.NIDE2353	4.951e-228	709.0	COG0840@1|root,COG0840@2|Bacteria,3J0N9@40117|Nitrospirae	40117|Nitrospirae	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR34280931_k127_144639_3	63737.Npun_R3329	1.635e-37	161.0	COG0286@1|root,COG0286@2|Bacteria,1G70A@1117|Cyanobacteria,1HNVZ@1161|Nostocales	1117|Cyanobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
SRR34280931_k127_144639_2	553219.CAMSH0001_2035	5.506e-89	304.0	2ACHM@1|root,3123M@2|Bacteria	2|Bacteria	L	MamI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_MamI
SRR34280931_k127_144639_5	517722.AEUE01000010_gene547	2.3e-24	106.0	COG1813@1|root,COG1813@2|Bacteria,1NANQ@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR34280931_k127_144639_7	1096930.L284_06435	2.218e-11	69.0	2EIFY@1|root,33C7A@2|Bacteria,1NHA0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SRR34280931_k127_144639_6	629773.AORY01000020_gene2972	2.713e-15	82.0	28WTV@1|root,2ZITC@2|Bacteria,1P6GF@1224|Proteobacteria,2UWCD@28211|Alphaproteobacteria,2KBTT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_144639_9	1030157.AFMP01000016_gene2341	8.545e-05	51.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,2K5PJ@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR34280931_k127_144639_1	1096930.L284_06400	5.571e-94	330.0	COG0467@1|root,COG0467@2|Bacteria,1R9I6@1224|Proteobacteria,2UQ5P@28211|Alphaproteobacteria,2K4A5@204457|Sphingomonadales	204457|Sphingomonadales	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
SRR34280931_k127_144639_0	1096930.L284_06395	4.662e-129	426.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,2K2X4@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
SRR34280931_k127_144639_4	1144307.PMI04_00912	4.422e-32	128.0	COG1403@1|root,COG1403@2|Bacteria,1RATU@1224|Proteobacteria,2UMSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	HNH nucleases	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR34280931_k127_1448887_7	330214.NIDE4010	5.33e-38	146.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
SRR34280931_k127_1448887_4	330214.NIDE4013	1.427e-75	254.0	2EQ22@1|root,33HNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1448887_2	330214.NIDE4014	4.598e-221	688.0	2EUIU@1|root,33N0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1448887_0	330214.NIDE4016	0.0	1101.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
SRR34280931_k127_1448887_1	330214.NIDE4018	0.0	1024.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR34280931_k127_1448887_9	398512.JQKC01000009_gene402	6.534e-31	133.0	2ECEQ@1|root,336CX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_1449521_0	1254432.SCE1572_00900	3.5e-163	531.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2YYSN@29|Myxococcales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR34280931_k127_1449521_5	1089552.KI911559_gene802	5.857e-10	72.0	COG3307@1|root,COG3307@2|Bacteria,1RBK5@1224|Proteobacteria	1224|Proteobacteria	M	Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR34280931_k127_1449521_4	269796.Rru_A2739	4.933e-10	71.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_1449521_3	861299.J421_3499	6.435e-16	80.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K02687	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Methyltransf_12,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31,PrmA
SRR34280931_k127_1449521_1	886293.Sinac_3903	9.284e-35	139.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K02687	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Methyltransf_12,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31,PrmA
SRR34280931_k127_1449521_2	1173023.KE650771_gene4915	5.701e-18	84.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_164950_30	1232410.KI421428_gene1135	1.059e-147	485.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42QDJ@68525|delta/epsilon subdivisions,2WIJ9@28221|Deltaproteobacteria,43S4B@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.10,3.2.1.20	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
SRR34280931_k127_164950_44	330214.NIDE1448	1.648e-100	334.0	COG0692@1|root,COG0692@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR34280931_k127_164950_67	330214.NIDE1470	1.603e-34	141.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	DUF3574
SRR34280931_k127_164950_13	330214.NIDE1472	3.526e-255	790.0	COG0513@1|root,COG0513@2|Bacteria,3J0ZA@40117|Nitrospirae	40117|Nitrospirae	F	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR34280931_k127_164950_8	330214.NIDE1475	6.191e-288	889.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,3J1FR@40117|Nitrospirae	2|Bacteria	KT	Evidence 2b Function of strongly homologous gene	fhlA	-	-	ko:K02584,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS,PAS_3,PAS_4,PAS_9,Sigma54_activat
SRR34280931_k127_164950_4	330214.NIDE3464	1.886e-318	984.0	COG0296@1|root,COG0296@2|Bacteria,3J0WY@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR34280931_k127_164950_41	477974.Daud_0851	1.313e-108	375.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,264Z9@186807|Peptococcaceae	186801|Clostridia	G	Alpha-amylase domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR34280931_k127_164950_11	1173027.Mic7113_3737	5.746e-259	815.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1G2ZI@1117|Cyanobacteria,1H9FE@1150|Oscillatoriales	1117|Cyanobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR34280931_k127_164950_58	671143.DAMO_1538	3.383e-61	220.0	COG0668@1|root,COG0668@2|Bacteria,2NQ6B@2323|unclassified Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
SRR34280931_k127_164950_42	671143.DAMO_1539	1.204e-101	346.0	COG0463@1|root,COG0463@2|Bacteria,2NQD9@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR34280931_k127_164950_33	909663.KI867151_gene3002	9.431e-133	434.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MQT9@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR34280931_k127_164950_9	1128421.JAGA01000004_gene2674	3.056e-275	854.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR34280931_k127_164950_68	891968.Anamo_1585	1.338e-31	132.0	COG0438@1|root,COG0438@2|Bacteria,3TC5G@508458|Synergistetes	508458|Synergistetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_164950_31	330214.NIDE1479	1.902e-139	444.0	COG3000@1|root,COG3000@2|Bacteria	330214.NIDE1479|-	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_164950_14	330214.NIDE1482	1.933e-236	744.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	mltC	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08306,ko:K08308,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iAF1260.b1193,iB21_1397.B21_01178,iBWG_1329.BWG_1018,iECBD_1354.ECBD_2429,iECB_1328.ECB_01168,iECDH10B_1368.ECDH10B_1246,iECDH1ME8569_1439.ECDH1ME8569_1132,iECD_1391.ECD_01168,iEcDH1_1363.EcDH1_2455,iEcolC_1368.EcolC_2432,iG2583_1286.G2583_3622,iJO1366.b1193,iUMNK88_1353.UMNK88_1507,iUMNK88_1353.UMNK88_3661,iY75_1357.Y75_RS06225	DUF3393,SLT
SRR34280931_k127_164950_49	330214.NIDE1483	1.504e-77	265.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR34280931_k127_164950_60	330214.NIDE1484	1.974e-52	194.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	sgaR	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR34280931_k127_164950_65	330214.NIDE1487	9.183e-43	160.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg
SRR34280931_k127_164950_39	330214.NIDE1489	1.058e-109	359.0	COG2197@1|root,COG2197@2|Bacteria,3J12Q@40117|Nitrospirae	40117|Nitrospirae	K	Product type r regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR34280931_k127_164950_5	330214.NIDE1491	3.771e-318	989.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
SRR34280931_k127_164950_77	330214.NIDE1492	2.845e-09	59.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE1492|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_164950_74	330214.NIDE1493	2.18e-15	78.0	COG4251@1|root,COG4251@2|Bacteria,3J0Y3@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR34280931_k127_164950_78	330214.NIDE1493	1.027e-08	65.0	COG4251@1|root,COG4251@2|Bacteria,3J0Y3@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR34280931_k127_164950_57	330214.NIDE1494	2.647e-61	214.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	yaeJ	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR34280931_k127_164950_59	330214.NIDE1495	3.901e-56	200.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR34280931_k127_164950_19	330214.NIDE1497	4.085e-196	611.0	COG1398@1|root,COG1398@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR34280931_k127_164950_21	330214.NIDE1500	1.036e-183	580.0	COG1560@1|root,COG1560@2|Bacteria,3J0SH@40117|Nitrospirae	40117|Nitrospirae	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR34280931_k127_164950_32	330214.NIDE1503	4.424e-139	445.0	COG0767@1|root,COG0767@2|Bacteria,3J0P4@40117|Nitrospirae	40117|Nitrospirae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR34280931_k127_164950_45	330214.NIDE1504	1.009e-97	331.0	COG1127@1|root,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR34280931_k127_164950_23	330214.NIDE1505	4.023e-169	535.0	COG1463@1|root,COG1463@2|Bacteria,3J0VP@40117|Nitrospirae	40117|Nitrospirae	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR34280931_k127_164950_46	330214.NIDE1507	5.26e-85	294.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE1507|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_164950_0	330214.NIDE1508	0.0	1496.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR34280931_k127_164950_3	330214.NIDE1509	3.776e-320	985.0	COG0442@1|root,COG0442@2|Bacteria,3J0EY@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR34280931_k127_164950_7	330214.NIDE1510	6.845e-294	903.0	COG0750@1|root,COG0750@2|Bacteria,3J0GI@40117|Nitrospirae	40117|Nitrospirae	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR34280931_k127_164950_16	330214.NIDE1511	2.284e-228	710.0	COG0743@1|root,COG0743@2|Bacteria,3J0B0@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR34280931_k127_164950_29	330214.NIDE1512	6.074e-148	473.0	COG4589@1|root,COG4589@2|Bacteria,3J1FV@40117|Nitrospirae	40117|Nitrospirae	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR34280931_k127_164950_28	330214.NIDE1513	1.412e-156	496.0	COG0020@1|root,COG0020@2|Bacteria,3J0HJ@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR34280931_k127_164950_6	330214.NIDE1514	2.345e-300	922.0	COG0312@1|root,COG0312@2|Bacteria,3J0F9@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR34280931_k127_164950_10	330214.NIDE1515	4.75e-267	825.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR34280931_k127_164950_43	330214.NIDE1516	1.251e-101	332.0	COG1881@1|root,COG1881@2|Bacteria,3J13B@40117|Nitrospirae	40117|Nitrospirae	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR34280931_k127_164950_37	330214.NIDE1518	5.989e-118	384.0	COG1573@1|root,COG1573@2|Bacteria,3J0MR@40117|Nitrospirae	40117|Nitrospirae	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR34280931_k127_164950_17	330214.NIDE1519	1.199e-220	692.0	COG1232@1|root,COG1232@2|Bacteria,3J1ES@40117|Nitrospirae	40117|Nitrospirae	C	Flavin containing amine oxidoreductase	-	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
SRR34280931_k127_164950_22	330214.NIDE1520	2.558e-180	565.0	COG1562@1|root,COG1562@2|Bacteria,3J17J@40117|Nitrospirae	40117|Nitrospirae	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR34280931_k127_164950_34	330214.NIDE1521	4.805e-131	427.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR34280931_k127_164950_35	330214.NIDE1522	3.157e-130	419.0	COG0637@1|root,COG0637@2|Bacteria,3J15X@40117|Nitrospirae	40117|Nitrospirae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR34280931_k127_164950_48	330214.NIDE1525	2.428e-78	266.0	COG0432@1|root,COG0432@2|Bacteria,3J1CB@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR34280931_k127_164950_56	330214.NIDE1527	8.037e-63	221.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K18491	ko04550,map04550	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF4157
SRR34280931_k127_164950_40	330214.NIDE1528	4.679e-109	357.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
SRR34280931_k127_164950_36	330214.NIDE1529	1.252e-126	417.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR34280931_k127_164950_12	330214.NIDE1530	1.614e-255	794.0	COG0515@1|root,COG0515@2|Bacteria	330214.NIDE1530|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR34280931_k127_164950_25	330214.NIDE1531	3.061e-165	522.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	trpH	-	3.1.3.97,4.1.2.13	ko:K01624,ko:K07053	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R00188,R01068,R01070,R01829,R02568,R11188	RC00078,RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR34280931_k127_164950_27	330214.NIDE1532	6.468e-161	512.0	COG1539@1|root,COG2520@1|root,COG1539@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	folB	-	1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8	ko:K01091,ko:K01633,ko:K15429	ko00630,ko00790,ko01100,ko01110,ko01130,map00630,map00790,map01100,map01110,map01130	M00126,M00840	R00597,R01334,R03504,R11037,R11073	RC00003,RC00017,RC00334,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	FolB,rRNA_methylase
SRR34280931_k127_164950_26	330214.NIDE1537	1.402e-161	514.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	PPC,Peptidase_C14,Sel1
SRR34280931_k127_164950_1	338966.Ppro_2343	0.0	1261.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,42NPE@68525|delta/epsilon subdivisions,2WJKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TIGRFAM CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
SRR34280931_k127_164950_15	338966.Ppro_2342	2.27e-231	724.0	COG1203@1|root,COG1203@2|Bacteria,1R911@1224|Proteobacteria,43CH8@68525|delta/epsilon subdivisions,2X7SD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TIGRFAM CRISPR-associated protein, Cse1 family	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
SRR34280931_k127_164950_51	338966.Ppro_2341	1.913e-76	259.0	2DMSE@1|root,32TCT@2|Bacteria	2|Bacteria	S	CRISPR-associated protein, Cse2	cse2	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
SRR34280931_k127_164950_24	497321.C664_05191	1.159e-167	534.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,2VP5P@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CT1975-like protein	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
SRR34280931_k127_164950_38	338966.Ppro_2339	2.425e-113	368.0	2DBXF@1|root,2ZBPB@2|Bacteria,1MUJ0@1224|Proteobacteria,42X1G@68525|delta/epsilon subdivisions,2WTG2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
SRR34280931_k127_164950_72	1122222.AXWR01000030_gene2331	1.202e-19	97.0	2DMIY@1|root,32RWI@2|Bacteria,1WK9X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM CRISPR associated protein	-	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
SRR34280931_k127_164950_20	330214.NIDE1548	4.014e-190	595.0	COG1518@1|root,COG1518@2|Bacteria	2|Bacteria	L	maintenance of DNA repeat elements	cas1	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0016888,GO:0016889,GO:0016893,GO:0016894,GO:0017108,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048256,GO:0050896,GO:0051276,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
SRR34280931_k127_164950_69	272568.GDI2203	1.391e-23	106.0	COG0847@1|root,COG0847@2|Bacteria,1N05B@1224|Proteobacteria,2UC74@28211|Alphaproteobacteria,2JXB5@204441|Rhodospirillales	204441|Rhodospirillales	L	CRISPR-associated protein (Cas_Cas2CT1978)	-	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
SRR34280931_k127_164950_75	1476583.DEIPH_ctg002orf0130	1.189e-12	70.0	2A20N@1|root,30QAJ@2|Bacteria,1WNAN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_191782_0	1254432.SCE1572_00900	3.064e-184	590.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2YYSN@29|Myxococcales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR34280931_k127_191782_9	760568.Desku_1744	1.416e-40	165.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR34280931_k127_191782_1	880072.Desac_1335	1.193e-105	366.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2MRZC@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_191782_11	1173027.Mic7113_5261	3.891e-09	68.0	COG2227@1|root,COG2227@2|Bacteria,1G9RY@1117|Cyanobacteria,1HDSS@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR34280931_k127_191782_5	234267.Acid_7807	5.334e-61	222.0	COG0726@1|root,COG0726@2|Bacteria,3Y95Z@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR34280931_k127_191782_7	330214.NIDE0880	3.505e-53	201.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR34280931_k127_191782_10	234267.Acid_4884	4.504e-10	70.0	2E0YU@1|root,32WF9@2|Bacteria,3Y7YV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR34280931_k127_191782_6	404589.Anae109_1206	2.873e-60	220.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25
SRR34280931_k127_191782_3	706587.Desti_1774	2.814e-91	312.0	COG2755@1|root,COG2755@2|Bacteria,1NCJV@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_191782_8	1247963.JPHU01000002_gene2447	2.607e-44	182.0	COG2931@1|root,COG3866@1|root,COG2931@2|Bacteria,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,2U57M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	-
SRR34280931_k127_191782_2	706587.Desti_4570	8.353e-96	325.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,42PIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase like family 2	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR34280931_k127_191782_4	543632.JOJL01000010_gene7179	2.659e-62	229.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR34280931_k127_200533_148	330214.NIDE4356	1.38e-16	82.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT,TrbL,VanY
SRR34280931_k127_200533_91	330214.NIDE4358	9.345e-89	295.0	2CG7F@1|root,2ZUI2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_100	330214.NIDE4359	3.701e-77	260.0	COG1832@1|root,COG1832@2|Bacteria,3J19F@40117|Nitrospirae	40117|Nitrospirae	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR34280931_k127_200533_74	330214.NIDE4360	3.456e-105	345.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR34280931_k127_200533_99	330214.NIDE4361	3.163e-77	262.0	COG5608@1|root,COG5608@2|Bacteria	2|Bacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR34280931_k127_200533_81	330214.NIDE4362	2.722e-98	322.0	COG1611@1|root,COG1611@2|Bacteria,3J0TX@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	-
SRR34280931_k127_200533_47	330214.NIDE4363	5.019e-154	489.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR34280931_k127_200533_21	330214.NIDE4364	5.594e-287	890.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE4364|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_24	330214.NIDE4367	8.536e-265	823.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldE2	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR34280931_k127_200533_17	330214.NIDE4368	1.347e-302	932.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR34280931_k127_200533_127	330214.NIDE4369	2.613e-48	175.0	COG3357@1|root,COG3357@2|Bacteria	2|Bacteria	K	Transcriptional regulator containing an HTH domain fused to a Zn-ribbon	-	-	-	ko:K07743	-	-	-	-	ko00000	-	-	-	HTH_5,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR34280931_k127_200533_141	330214.NIDE4370	1.617e-25	107.0	2EQIW@1|root,33I4X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_58	330214.NIDE4372	2.331e-136	437.0	COG3752@1|root,COG3752@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR34280931_k127_200533_128	330214.NIDE4373	4.52e-47	172.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
SRR34280931_k127_200533_55	330214.NIDE4374	3.676e-140	454.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR34280931_k127_200533_83	330214.NIDE4375	4.444e-98	326.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
SRR34280931_k127_200533_41	330214.NIDE4376	2.995e-172	550.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR34280931_k127_200533_10	330214.NIDE4377	0.0	1099.0	COG0488@1|root,COG0488@2|Bacteria,3J0WR@40117|Nitrospirae	40117|Nitrospirae	S	ABC transporter	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR34280931_k127_200533_67	330214.NIDE4378	1.074e-124	402.0	COG2930@1|root,COG2930@2|Bacteria	2|Bacteria	S	regulation of ruffle assembly	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SRR34280931_k127_200533_52	330214.NIDE4379	3.558e-144	463.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	MA20_19930	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
SRR34280931_k127_200533_50	330214.NIDE4381	1.709e-148	471.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	MA20_24420	-	-	ko:K06889,ko:K07000	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,UPF0227
SRR34280931_k127_200533_59	330214.NIDE4382	2.674e-135	432.0	COG0400@1|root,COG0400@2|Bacteria,3J1DU@40117|Nitrospirae	40117|Nitrospirae	S	Alpha/beta hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR34280931_k127_200533_7	330214.NIDE4383	0.0	1240.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_19	330214.NIDE4384	6.307e-297	914.0	COG0397@1|root,COG0397@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	ydiU	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
SRR34280931_k127_200533_109	330214.NIDE4385	1.996e-67	233.0	COG5609@1|root,COG5609@2|Bacteria,3J180@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
SRR34280931_k127_200533_13	330214.NIDE4386	0.0	1018.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05577	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR34280931_k127_200533_160	1274402.JQAJ01000003_gene703	2.423e-06	60.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,47EU0@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR34280931_k127_200533_0	330214.NIDE4388	0.0	1941.0	COG3002@1|root,COG3002@2|Bacteria,3J0VY@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
SRR34280931_k127_200533_113	330214.NIDE4390	1.292e-64	222.0	COG0347@1|root,COG0347@2|Bacteria,3J17N@40117|Nitrospirae	40117|Nitrospirae	K	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_57	1297569.MESS2_1570039	7.913e-139	451.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR34280931_k127_200533_36	330214.NIDE4395	6.93e-191	599.0	COG0457@1|root,COG0457@2|Bacteria,3J1CG@40117|Nitrospirae	330214.NIDE4395|-	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_18	330214.NIDE4396	1.087e-297	915.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR34280931_k127_200533_27	330214.NIDE4397	4.386e-249	772.0	COG0124@1|root,COG0124@2|Bacteria,3J0EC@40117|Nitrospirae	40117|Nitrospirae	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR34280931_k127_200533_118	330214.NIDE4398	4.413e-52	185.0	COG1553@1|root,COG1553@2|Bacteria,3J1AA@40117|Nitrospirae	40117|Nitrospirae	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_51	316067.Geob_0001	6.275e-147	477.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,43RXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR34280931_k127_200533_28	330214.NIDE0002	4.661e-235	728.0	COG0592@1|root,COG0592@2|Bacteria,3J0RU@40117|Nitrospirae	40117|Nitrospirae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR34280931_k127_200533_3	330214.NIDE0003	0.0	1586.0	COG0187@1|root,COG0187@2|Bacteria,3J0BB@40117|Nitrospirae	40117|Nitrospirae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR34280931_k127_200533_2	330214.NIDE0004	0.0	1586.0	COG0188@1|root,COG0188@2|Bacteria,3J0EH@40117|Nitrospirae	40117|Nitrospirae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR34280931_k127_200533_155	1121918.ARWE01000001_gene840	2.707e-10	67.0	COG5512@1|root,COG5512@2|Bacteria,1N24G@1224|Proteobacteria,42TXW@68525|delta/epsilon subdivisions,2WQ15@28221|Deltaproteobacteria,43SMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR34280931_k127_200533_88	330214.NIDE0007	2.165e-91	301.0	COG0691@1|root,COG0691@2|Bacteria,3J0Q4@40117|Nitrospirae	40117|Nitrospirae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR34280931_k127_200533_97	330214.NIDE0008	2.964e-80	269.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR34280931_k127_200533_60	330214.NIDE0009	8.059e-133	428.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR34280931_k127_200533_42	330214.NIDE0010	1.959e-170	538.0	COG1741@1|root,COG1741@2|Bacteria,3J125@40117|Nitrospirae	40117|Nitrospirae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR34280931_k127_200533_76	330214.NIDE0011	2.928e-102	338.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR34280931_k127_200533_94	330214.NIDE0012	1.359e-84	281.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	fosB2	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR34280931_k127_200533_33	330214.NIDE0014	1.125e-203	638.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR34280931_k127_200533_110	330214.NIDE0015	9.363e-67	229.0	2CIIF@1|root,315FB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_96	330214.NIDE0016	2.154e-81	274.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR34280931_k127_200533_126	330214.NIDE0017	2.294e-48	175.0	COG3369@1|root,COG3369@2|Bacteria,3J1A6@40117|Nitrospirae	40117|Nitrospirae	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR34280931_k127_200533_64	330214.NIDE0018	5.928e-129	415.0	COG1018@1|root,COG1018@2|Bacteria,3J196@40117|Nitrospirae	40117|Nitrospirae	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_9	330214.NIDE0029	0.0	1125.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SRR34280931_k127_200533_161	330214.NIDE0040	3.723e-05	46.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR34280931_k127_200533_37	330214.NIDE0031	2.091e-186	587.0	COG1566@1|root,COG1566@2|Bacteria,3J0TB@40117|Nitrospirae	40117|Nitrospirae	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR34280931_k127_200533_11	330214.NIDE0032	0.0	1098.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_200533_30	330214.NIDE0033	3.5e-213	668.0	COG0842@1|root,COG0842@2|Bacteria,3J0MP@40117|Nitrospirae	40117|Nitrospirae	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR34280931_k127_200533_32	330214.NIDE0034	2.934e-210	670.0	COG0842@1|root,COG0842@2|Bacteria,3J115@40117|Nitrospirae	40117|Nitrospirae	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR34280931_k127_200533_87	330214.NIDE0036	4.982e-92	304.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR34280931_k127_200533_130	330214.NIDE0039	6.108e-46	167.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR34280931_k127_200533_98	330214.NIDE0040	1.668e-78	265.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR34280931_k127_200533_133	227377.CBU_0943	9.195e-41	154.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese,SNARE_assoc
SRR34280931_k127_200533_159	640512.BC1003_5144	3.1e-08	57.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR34280931_k127_200533_107	330214.NIDE0044	4.628e-71	242.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR34280931_k127_200533_65	330214.NIDE0045	2.998e-128	413.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR34280931_k127_200533_92	261292.Nit79A3_2506	5.231e-88	297.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,2WC2A@28216|Betaproteobacteria,37479@32003|Nitrosomonadales	28216|Betaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR34280931_k127_200533_34	1340493.JNIF01000003_gene3840	7.934e-198	637.0	COG1252@1|root,COG1252@2|Bacteria,3Y308@57723|Acidobacteria	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,Pyr_redox_2,cNMP_binding
SRR34280931_k127_200533_71	330214.NIDE0047	1.018e-111	364.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	tdsD	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR34280931_k127_200533_69	330214.NIDE0048	1.861e-114	372.0	COG0500@1|root,COG2226@2|Bacteria,3J13G@40117|Nitrospirae	40117|Nitrospirae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_66	330214.NIDE0049	1.565e-126	408.0	COG1028@1|root,COG1028@2|Bacteria,3J0J6@40117|Nitrospirae	330214.NIDE0049|-	IQ	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR34280931_k127_200533_108	330214.NIDE0050	1.153e-69	238.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
SRR34280931_k127_200533_77	330214.NIDE0051	1.37e-100	334.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR34280931_k127_200533_104	1121403.AUCV01000029_gene2691	7.347e-74	256.0	COG0693@1|root,COG0693@2|Bacteria,1QV0E@1224|Proteobacteria,43BN3@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	protein deglycase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_53	330214.NIDE0052	1.193e-143	462.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Lactamase_B,Lactamase_B_5
SRR34280931_k127_200533_44	330214.NIDE0055	3.566e-160	509.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
SRR34280931_k127_200533_38	330214.NIDE0057	3.746e-186	586.0	COG1858@1|root,COG1858@2|Bacteria,3J0GH@40117|Nitrospirae	40117|Nitrospirae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR34280931_k127_200533_16	330214.NIDE0058	5.141e-314	968.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
SRR34280931_k127_200533_43	330214.NIDE0059	1.046e-167	535.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
SRR34280931_k127_200533_138	330214.NIDE0059	3.866e-29	117.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
SRR34280931_k127_200533_143	944479.JQLX01000011_gene832	5.451e-25	111.0	COG0507@1|root,COG0782@1|root,COG1112@1|root,COG0507@2|Bacteria,COG0782@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,42PMB@68525|delta/epsilon subdivisions,2WJR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
SRR34280931_k127_200533_124	290317.Cpha266_1489	3.895e-50	191.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406,ko:K21470	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01002,ko01011,ko02035	-	-	-	DUF4325,HATPase_c,HisKA_3
SRR34280931_k127_200533_150	1500306.JQLA01000011_gene3697	9.668e-16	79.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2TU9J@28211|Alphaproteobacteria,4B9F0@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR34280931_k127_200533_89	330214.NIDE2804	4.135e-91	310.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
SRR34280931_k127_200533_149	365044.Pnap_1660	3.111e-16	83.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,2W0X0@28216|Betaproteobacteria,4AJVZ@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	ko:K08169	-	-	-	-	ko00000,ko02000	2.A.1.3.17	-	-	MFS_1,MFS_3
SRR34280931_k127_200533_70	330214.NIDE0140	3.941e-114	368.0	COG5514@1|root,COG5514@2|Bacteria	2|Bacteria	-	-	MA20_21045	-	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR34280931_k127_200533_6	330214.NIDE0143	0.0	1244.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
SRR34280931_k127_200533_4	330214.NIDE0144	0.0	1483.0	COG0380@1|root,COG0380@2|Bacteria,3J109@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR34280931_k127_200533_62	330214.NIDE0145	1.233e-129	419.0	COG1877@1|root,COG1877@2|Bacteria,3J0UY@40117|Nitrospirae	40117|Nitrospirae	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR34280931_k127_200533_82	330214.NIDE0146	4.136e-98	324.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR34280931_k127_200533_56	330214.NIDE0147	9.318e-140	448.0	COG2326@1|root,COG2326@2|Bacteria,3J111@40117|Nitrospirae	40117|Nitrospirae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR34280931_k127_200533_68	330214.NIDE0149	2.007e-123	401.0	2ETF9@1|root,33KZ8@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
SRR34280931_k127_200533_80	330214.NIDE0150	1.216e-98	327.0	2ETF9@1|root,33KZ8@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
SRR34280931_k127_200533_134	351160.RCIX2417	1.582e-40	160.0	COG0584@1|root,arCOG00701@2157|Archaea,2XXRI@28890|Euryarchaeota,2NB63@224756|Methanomicrobia	224756|Methanomicrobia	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR34280931_k127_200533_140	870187.Thini_2708	6.493e-27	126.0	COG0515@1|root,COG0515@2|Bacteria,1QXK0@1224|Proteobacteria,1T3DE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	Pkinase,TIR_2
SRR34280931_k127_200533_122	1122921.KB898193_gene2468	7.227e-51	202.0	COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli,26RR0@186822|Paenibacillaceae	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	pkn1	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR34280931_k127_200533_145	631362.Thi970DRAFT_04339	3.211e-24	106.0	2DMHJ@1|root,32RM0@2|Bacteria,1NDZ0@1224|Proteobacteria,1SEPY@1236|Gammaproteobacteria,1WZRE@135613|Chromatiales	135613|Chromatiales	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR34280931_k127_200533_73	306281.AJLK01000113_gene505	8.7e-109	363.0	COG3344@1|root,COG3344@2|Bacteria,1G2NC@1117|Cyanobacteria,1JJNB@1189|Stigonemataceae	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
SRR34280931_k127_200533_156	768671.ThimaDRAFT_4463	4.17e-10	65.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S2PN@1236|Gammaproteobacteria,1WYNY@135613|Chromatiales	135613|Chromatiales	KLT	PFAM Sulphatase-modifying factor	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,PG_binding_1,Pkinase
SRR34280931_k127_200533_152	247490.KSU1_B0531	4.194e-13	81.0	COG1262@1|root,COG1262@2|Bacteria,2J3GG@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_200533_165	1501230.ET33_27670	0.0008648	52.0	COG0265@1|root,COG0265@2|Bacteria,1VVV4@1239|Firmicutes,4I6QJ@91061|Bacilli,26UAW@186822|Paenibacillaceae	91061|Bacilli	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR34280931_k127_200533_137	478741.JAFS01000002_gene286	1.523e-37	160.0	COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SRR34280931_k127_200533_86	330214.NIDE0155	3.469e-92	306.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR34280931_k127_200533_111	330214.NIDE0156	2.94e-66	228.0	COG2154@1|root,COG2154@2|Bacteria	2|Bacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR34280931_k127_200533_8	330214.NIDE0158	0.0	1203.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_200533_112	330214.NIDE0159	5.691e-65	222.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	yurZ	-	2.3.1.12,4.1.1.44	ko:K00627,ko:K01607	ko00010,ko00020,ko00362,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00020,map00362,map00620,map01100,map01110,map01120,map01130,map01200,map01220	M00307	R00209,R02569,R03470	RC00004,RC00938,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CMD
SRR34280931_k127_200533_54	330214.NIDE0161	2.522e-141	452.0	COG0483@1|root,COG0483@2|Bacteria,3J0I4@40117|Nitrospirae	40117|Nitrospirae	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR34280931_k127_200533_40	330214.NIDE0164	2.134e-181	570.0	COG0774@1|root,COG0774@2|Bacteria,3J0JG@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SRR34280931_k127_200533_114	1123320.KB889749_gene4539	3.97e-58	209.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR34280931_k127_200533_29	330214.NIDE0166	3.326e-225	700.0	COG1063@1|root,COG4585@1|root,COG1063@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	1.1.1.103,2.7.13.3	ko:K00060,ko:K07777	ko00260,ko02020,map00260,map02020	M00478	R01465	RC00525	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3,NAS
SRR34280931_k127_200533_103	330214.NIDE0167	4.362e-75	254.0	COG1327@1|root,COG1327@2|Bacteria,3J14C@40117|Nitrospirae	40117|Nitrospirae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR34280931_k127_200533_23	330214.NIDE0168	1.608e-266	824.0	COG0112@1|root,COG0112@2|Bacteria,3J0CB@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR34280931_k127_200533_93	330214.NIDE0169	7.788e-86	289.0	COG0359@1|root,COG0359@2|Bacteria,3J0MQ@40117|Nitrospirae	40117|Nitrospirae	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR34280931_k127_200533_147	330214.NIDE2850	3.744e-21	100.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,Glycos_transf_2,Methyltransf_11
SRR34280931_k127_200533_132	306281.AJLK01000134_gene1542	8.75e-43	168.0	COG1215@1|root,COG1215@2|Bacteria,1GPY1@1117|Cyanobacteria,1JMSI@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_200533_162	1121438.JNJA01000003_gene2936	0.0002058	53.0	29U1C@1|root,30FAJ@2|Bacteria,1PYST@1224|Proteobacteria,435J3@68525|delta/epsilon subdivisions,2X9AM@28221|Deltaproteobacteria,2M7Z0@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_146	330214.NIDE0189	6.194e-22	97.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR34280931_k127_200533_45	330214.NIDE0190	6.981e-160	507.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	ycgE	-	-	ko:K21089,ko:K21972,ko:K22491	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR34280931_k127_200533_35	330214.NIDE0192	1.912e-197	619.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
SRR34280931_k127_200533_31	330214.NIDE0193	7.441e-212	660.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
SRR34280931_k127_200533_48	330214.NIDE0195	1.908e-151	482.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_200533_49	330214.NIDE0198	2.005e-150	480.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR34280931_k127_200533_115	330214.NIDE0200	1.963e-57	205.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR34280931_k127_200533_22	330214.NIDE0203	2.679e-271	839.0	COG0415@1|root,COG0415@2|Bacteria,3J0IW@40117|Nitrospirae	40117|Nitrospirae	H	Belongs to the DNA photolyase family	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR34280931_k127_200533_39	330214.NIDE0204	7.546e-184	579.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
SRR34280931_k127_200533_78	330214.NIDE0206	2.213e-100	328.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_200533_79	330214.NIDE0218	1.385e-99	327.0	COG0461@1|root,COG0461@2|Bacteria,3J0T8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR34280931_k127_200533_105	330214.NIDE0220	1.418e-73	250.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR34280931_k127_200533_46	330214.NIDE0221	3.1e-154	493.0	COG3698@1|root,COG3698@2|Bacteria	2|Bacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SRR34280931_k127_200533_14	330214.NIDE0222	3.013e-316	972.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_200533_90	330214.NIDE0223	1.314e-89	298.0	COG0745@1|root,COG0745@2|Bacteria,3J151@40117|Nitrospirae	40117|Nitrospirae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_200533_25	330214.NIDE0224	3.089e-262	815.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,3J12S@40117|Nitrospirae	40117|Nitrospirae	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA
SRR34280931_k127_200533_20	330214.NIDE0225	2.985e-293	903.0	COG1007@1|root,COG1007@2|Bacteria,3J0FN@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR34280931_k127_200533_12	330214.NIDE0226	0.0	1035.0	COG1008@1|root,COG1008@2|Bacteria,3J0EQ@40117|Nitrospirae	2|Bacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	ndhD	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iJN678.ndhD2	Oxidored_q5_N,Proton_antipo_M
SRR34280931_k127_200533_15	330214.NIDE0227	1.958e-314	966.0	COG1008@1|root,COG1008@2|Bacteria,3J0EQ@40117|Nitrospirae	2|Bacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR34280931_k127_200533_5	330214.NIDE0228	0.0	1306.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05568,ko:K12139	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR34280931_k127_200533_125	330214.NIDE0229	6.533e-49	176.0	COG0713@1|root,COG0713@2|Bacteria,3J1AK@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR34280931_k127_200533_84	330214.NIDE0230	3.348e-94	312.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR34280931_k127_200533_61	330214.NIDE0231	4.064e-130	416.0	COG1143@1|root,COG1143@2|Bacteria,3J0N0@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR34280931_k127_200533_1	330214.NIDE0232	0.0	1696.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	2|Bacteria	C	Molydopterin dinucleotide binding domain	hcnA	-	1.4.99.5,1.5.3.1	ko:K00302,ko:K10814	ko00260,ko00460,ko01100,ko01110,map00260,map00460,map01100,map01110	-	R00374,R00610,R05704	RC00060,RC00557,RC02808	ko00000,ko00001,ko01000,ko02042	-	-	-	Fer2_4
SRR34280931_k127_204531_18	330214.NIDE1896	2.06e-45	164.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR34280931_k127_204531_11	330214.NIDE1902	2.063e-108	352.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_204531_3	330214.NIDE1906	4.841e-219	685.0	COG0420@1|root,COG0420@2|Bacteria,3J0UK@40117|Nitrospirae	40117|Nitrospirae	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR34280931_k127_204531_0	330214.NIDE1907	0.0	1257.0	COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria,3J110@40117|Nitrospirae	40117|Nitrospirae	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
SRR34280931_k127_204531_9	330214.NIDE1909	2.199e-124	401.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
SRR34280931_k127_204531_10	330214.NIDE1910	9.17e-122	396.0	COG1584@1|root,COG1584@2|Bacteria	2|Bacteria	S	GPR1 FUN34 yaaH family protein	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
SRR34280931_k127_204531_7	330214.NIDE1914	4.304e-144	458.0	COG1194@1|root,COG1194@2|Bacteria,3J160@40117|Nitrospirae	40117|Nitrospirae	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR34280931_k127_204531_14	330214.NIDE1915	5.976e-76	255.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
SRR34280931_k127_204531_6	330214.NIDE1916	1.513e-147	467.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2
SRR34280931_k127_204531_1	330214.NIDE1919	1.432e-287	884.0	COG0621@1|root,COG0621@2|Bacteria,3J0GE@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR34280931_k127_204531_2	330214.NIDE1920	1.888e-244	759.0	COG0621@1|root,COG0621@2|Bacteria,3J112@40117|Nitrospirae	40117|Nitrospirae	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR34280931_k127_204531_5	330214.NIDE1922	8.033e-148	488.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_204531_12	330214.NIDE1923	5.741e-107	350.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR34280931_k127_204531_13	330214.NIDE1925	9.059e-88	295.0	COG0589@1|root,COG0589@2|Bacteria,3J1E9@40117|Nitrospirae	40117|Nitrospirae	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_204531_16	330214.NIDE1926	1.634e-71	243.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	amcY	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
SRR34280931_k127_204531_4	330214.NIDE1927	1.602e-168	532.0	COG0589@1|root,COG0589@2|Bacteria,3J1A7@40117|Nitrospirae	40117|Nitrospirae	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_218994_0	330214.NIDE2534	1.785e-184	581.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	aniA	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR34280931_k127_218994_1	330214.NIDE2535	6.821e-129	416.0	COG0664@1|root,COG0664@2|Bacteria,3J18E@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR34280931_k127_218994_2	330214.NIDE2536	1.298e-124	400.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR34280931_k127_225504_7	330214.NIDE3038	7.661e-112	363.0	COG0673@1|root,COG0673@2|Bacteria,3J0M7@40117|Nitrospirae	40117|Nitrospirae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR34280931_k127_225504_6	330214.NIDE3039	3.555e-160	517.0	COG3494@1|root,COG3494@2|Bacteria,3J0KP@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR34280931_k127_225504_5	330214.NIDE3040	3.641e-165	520.0	COG1043@1|root,COG1043@2|Bacteria,3J0G6@40117|Nitrospirae	40117|Nitrospirae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR34280931_k127_225504_9	330214.NIDE3041	2.667e-88	292.0	COG0764@1|root,COG0764@2|Bacteria,3J0NG@40117|Nitrospirae	40117|Nitrospirae	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR34280931_k127_225504_10	330214.NIDE3042	4.604e-80	270.0	COG2825@1|root,COG2825@2|Bacteria,3J1AH@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR34280931_k127_225504_8	330214.NIDE3043	1.354e-93	310.0	COG2825@1|root,COG2825@2|Bacteria,3J1AH@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR34280931_k127_225504_1	330214.NIDE3044	0.0	1461.0	COG4775@1|root,COG4775@2|Bacteria,3J0AC@40117|Nitrospirae	40117|Nitrospirae	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR34280931_k127_225504_3	330214.NIDE3045	9.207e-186	585.0	COG1210@1|root,COG1210@2|Bacteria,3J0B2@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR34280931_k127_225504_0	330214.NIDE3046	0.0	1526.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR34280931_k127_225504_4	330214.NIDE3047	1.804e-170	542.0	COG0611@1|root,COG0611@2|Bacteria,3J0TF@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR34280931_k127_225504_11	330214.NIDE3048	8.966e-79	268.0	COG3216@1|root,COG3216@2|Bacteria,3J1DC@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
SRR34280931_k127_225504_2	330214.NIDE3049	4.339e-275	850.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR34280931_k127_241056_19	330214.NIDE0511	3.01e-137	439.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
SRR34280931_k127_241056_6	330214.NIDE0508	2.054e-234	729.0	COG1134@1|root,COG1134@2|Bacteria,3J142@40117|Nitrospirae	2|Bacteria	GM	Evidence 2b Function of strongly homologous gene	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_241056_17	330214.NIDE0507	2.021e-160	507.0	COG1682@1|root,COG1682@2|Bacteria,3J1DI@40117|Nitrospirae	2|Bacteria	U	ABC-2 type transporter	wzm	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR34280931_k127_241056_36	330214.NIDE0505	1.273e-46	172.0	COG4446@1|root,COG4446@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
SRR34280931_k127_241056_3	330214.NIDE0503	1.086e-252	781.0	COG0436@1|root,COG0436@2|Bacteria,3J0G2@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_241056_27	330214.NIDE0502	1.346e-103	338.0	COG0801@1|root,COG0801@2|Bacteria,3J19N@40117|Nitrospirae	40117|Nitrospirae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR34280931_k127_241056_20	330214.NIDE0501	2.027e-136	442.0	COG0414@1|root,COG0414@2|Bacteria,3J0KR@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR34280931_k127_241056_34	330214.NIDE0499	4.989e-65	224.0	COG4696@1|root,COG4696@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	XK27_03185	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Acetyltransf_3,Hydrolase_3,PRA-PH
SRR34280931_k127_241056_5	330214.NIDE0498	5.615e-249	774.0	COG1322@1|root,COG1322@2|Bacteria,3J15T@40117|Nitrospirae	40117|Nitrospirae	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR34280931_k127_241056_0	330214.NIDE0497	0.0	1180.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,3J0QY@40117|Nitrospirae	40117|Nitrospirae	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR34280931_k127_241056_10	330214.NIDE0496	1.622e-211	666.0	COG2379@1|root,COG2379@2|Bacteria,3J16T@40117|Nitrospirae	40117|Nitrospirae	H	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR34280931_k127_241056_13	330214.NIDE0495	1.568e-184	582.0	COG0741@1|root,COG0741@2|Bacteria,3J0J4@40117|Nitrospirae	2|Bacteria	M	Lysin motif	mltD_2	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR34280931_k127_241056_22	330214.NIDE0494	5.661e-124	400.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
SRR34280931_k127_241056_21	330214.NIDE0493	2.941e-131	424.0	COG0176@1|root,COG0176@2|Bacteria,3J0YY@40117|Nitrospirae	40117|Nitrospirae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR34280931_k127_241056_38	330214.NIDE0491	7.115e-29	117.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	tmoA	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494	1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1	ko:K00688,ko:K15760,ko:K16157,ko:K16242,ko:K18223,ko:K22353,ko:K22357	ko00361,ko00362,ko00500,ko00623,ko00625,ko00640,ko00680,ko01100,ko01110,ko01120,ko01200,ko01220,ko02026,ko04217,ko04910,ko04922,ko04931,map00361,map00362,map00500,map00623,map00625,map00640,map00680,map01100,map01110,map01120,map01200,map01220,map02026,map04217,map04910,map04922,map04931	M00174,M00538,M00548	R01142,R02111,R02550,R03560,R03562,R03608,R05444,R05666,R10042,R10043,R10702,R11901	RC00046,RC00173,RC00269,RC00490,RC01383,RC03249	ko00000,ko00001,ko00002,ko01000	-	GT35	-	Phenol_Hydrox,YHS
SRR34280931_k127_241056_14	330214.NIDE0490	1.146e-162	514.0	COG0289@1|root,COG0289@2|Bacteria,3J0IJ@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR34280931_k127_241056_15	330214.NIDE0489	2.608e-162	514.0	COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR34280931_k127_241056_4	330214.NIDE0488	1.637e-251	778.0	COG0019@1|root,COG0019@2|Bacteria,3J0CR@40117|Nitrospirae	40117|Nitrospirae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR34280931_k127_241056_1	330214.NIDE0486	2.125e-281	868.0	COG0165@1|root,COG0165@2|Bacteria,3J0EN@40117|Nitrospirae	40117|Nitrospirae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR34280931_k127_241056_2	330214.NIDE0485	4.593e-259	799.0	COG0137@1|root,COG0137@2|Bacteria,3J0BU@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR34280931_k127_241056_11	330214.NIDE0484	1.625e-191	600.0	COG0078@1|root,COG0078@2|Bacteria,3J0G7@40117|Nitrospirae	40117|Nitrospirae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR34280931_k127_241056_7	330214.NIDE0483	3.332e-232	725.0	COG4992@1|root,COG4992@2|Bacteria,3J0AB@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR34280931_k127_241056_24	330214.NIDE0482	1.201e-120	389.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	DUF2628,N_methyl,Pilin
SRR34280931_k127_241056_23	330214.NIDE0478	3.284e-121	391.0	COG0588@1|root,COG0588@2|Bacteria,3J118@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR34280931_k127_241056_9	330214.NIDE0474	8.418e-213	662.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR34280931_k127_241056_8	330214.NIDE0473	8.384e-214	666.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
SRR34280931_k127_241056_16	330214.NIDE0471	1.025e-161	514.0	COG0037@1|root,COG0037@2|Bacteria	2|Bacteria	D	tRNA processing	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.1.15,6.3.4.19	ko:K04075,ko:K14058,ko:K21947	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR34280931_k127_241056_29	330214.NIDE0469	2.068e-97	324.0	COG0225@1|root,COG0225@2|Bacteria,3J12A@40117|Nitrospirae	40117|Nitrospirae	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR34280931_k127_241056_12	330214.NIDE0468	6.156e-185	578.0	COG0364@1|root,COG0364@2|Bacteria,3J0XD@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR34280931_k127_268100_38	330214.NIDE1721	1.503e-31	126.0	2EU10@1|root,33MI2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_268100_30	330214.NIDE1723	6.112e-82	274.0	COG0251@1|root,COG0251@2|Bacteria,3J144@40117|Nitrospirae	40117|Nitrospirae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR34280931_k127_268100_6	330214.NIDE1724	0.0	1052.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,Glug,TIG
SRR34280931_k127_268100_17	330214.NIDE1725	4.12e-172	544.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR34280931_k127_268100_27	330214.NIDE1726	4.322e-111	364.0	COG1385@1|root,COG1385@2|Bacteria,3J18K@40117|Nitrospirae	40117|Nitrospirae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR34280931_k127_268100_12	330214.NIDE1727	1.647e-237	735.0	COG0484@1|root,COG0484@2|Bacteria,3J0A7@40117|Nitrospirae	40117|Nitrospirae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR34280931_k127_268100_5	330214.NIDE1728	0.0	1206.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR34280931_k127_268100_29	330214.NIDE1729	3.437e-95	314.0	COG0576@1|root,COG0576@2|Bacteria,3J0QP@40117|Nitrospirae	40117|Nitrospirae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR34280931_k127_268100_20	330214.NIDE1730	8.78e-149	472.0	COG1521@1|root,COG1521@2|Bacteria,3J0TR@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR34280931_k127_268100_36	1144275.COCOR_03821	1.971e-45	176.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR34280931_k127_268100_24	330214.NIDE1732	5.542e-137	441.0	COG0157@1|root,COG0157@2|Bacteria,3J0JY@40117|Nitrospirae	40117|Nitrospirae	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR34280931_k127_268100_3	330214.NIDE1733	0.0	1637.0	COG0525@1|root,COG0525@2|Bacteria,3J0B9@40117|Nitrospirae	40117|Nitrospirae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR34280931_k127_268100_19	330214.NIDE1735	2.163e-158	507.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	VP1245	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GAF_2,GGDEF,HATPase_c,HD,HisKA,Response_reg,cNMP_binding
SRR34280931_k127_268100_35	32057.KB217478_gene4484	4.061e-47	178.0	COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1HJ2D@1161|Nostocales	1117|Cyanobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR34280931_k127_268100_25	330214.NIDE1737	9.344e-132	422.0	COG0846@1|root,COG0846@2|Bacteria,3J15J@40117|Nitrospirae	40117|Nitrospirae	K	Belongs to the sirtuin family. Class	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR34280931_k127_268100_9	330214.NIDE1738	1.517e-266	823.0	COG1893@1|root,COG2041@1|root,COG1893@2|Bacteria,COG2041@2|Bacteria,3J0S5@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR34280931_k127_268100_45	706587.Desti_1029	2.021e-05	59.0	COG0457@1|root,COG0666@1|root,COG5276@1|root,COG0457@2|Bacteria,COG0666@2|Bacteria,COG5276@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2WQ9N@28221|Deltaproteobacteria,2MRS9@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	S	Ankyrin repeat-containing protein	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR34280931_k127_268100_40	886293.Sinac_5443	8.437e-27	130.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR34280931_k127_268100_13	330214.NIDE1739	7.409e-226	705.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR34280931_k127_268100_8	330214.NIDE1740	2.612e-291	900.0	COG2251@1|root,COG2251@2|Bacteria	2|Bacteria	-	-	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF2779,HHH_5,KH_5,NusA_N,S1
SRR34280931_k127_268100_10	1038858.AXBA01000027_gene1418	1.327e-240	748.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR34280931_k127_268100_1	187303.BN69_0149	0.0	3201.0	COG1201@1|root,COG1205@1|root,COG1201@2|Bacteria,COG1205@2|Bacteria,1MVGH@1224|Proteobacteria,2U1X5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF1998,Helicase_C
SRR34280931_k127_268100_4	187303.BN69_0150	0.0	1634.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2TUMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SRR34280931_k127_268100_2	290633.GOX1505	0.0	2326.0	COG1002@1|root,COG1002@2|Bacteria,1NM9N@1224|Proteobacteria,2TSRS@28211|Alphaproteobacteria,2JR76@204441|Rhodospirillales	204441|Rhodospirillales	V	COG1002 Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR34280931_k127_268100_11	290633.GOX1506	1.104e-237	751.0	COG5293@1|root,COG5293@2|Bacteria,1QYHR@1224|Proteobacteria,2U34N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
SRR34280931_k127_268100_23	187303.BN69_0153	2.759e-140	449.0	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2TS2Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
SRR34280931_k127_268100_44	883078.HMPREF9695_04480	2.278e-08	55.0	2E937@1|root,333C5@2|Bacteria,1N12G@1224|Proteobacteria,2UDB8@28211|Alphaproteobacteria,3K06Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Conjugal transfer protein TraD	-	-	-	-	-	-	-	-	-	-	-	-	TraD
SRR34280931_k127_268100_0	330214.NIDE1742	0.0	5086.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,MbtH,PP-binding,Thioesterase
SRR34280931_k127_268100_7	330214.NIDE1743	0.0	998.0	COG4615@1|root,COG4615@2|Bacteria	2|Bacteria	V	microcin transport	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_268100_31	330214.NIDE1744	1.187e-81	279.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	hetI	-	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR34280931_k127_268100_32	330214.NIDE1745	2.003e-76	260.0	COG0590@1|root,COG0590@2|Bacteria,3J0PE@40117|Nitrospirae	40117|Nitrospirae	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR34280931_k127_268100_16	330214.NIDE1746	2.445e-179	568.0	COG4372@1|root,COG5343@1|root,COG4372@2|Bacteria,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	LZ_Tnp_IS66,RskA,zf-HC2
SRR34280931_k127_268100_26	330214.NIDE1747	1.969e-117	380.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR34280931_k127_268100_18	330214.NIDE1748	1.089e-164	525.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
SRR34280931_k127_268100_34	330214.NIDE1750	2.013e-59	207.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE1750|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_268100_22	330214.NIDE1751	5.286e-147	467.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE1751|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_268100_15	330214.NIDE3139	1.789e-198	632.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K03287	-	-	-	-	ko00000	1.B.17	-	-	OEP
SRR34280931_k127_268100_28	330214.NIDE3138	1.359e-103	348.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR34280931_k127_268100_14	330214.NIDE3137	4.598e-203	641.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
SRR34280931_k127_268100_21	330214.NIDE3136	3.484e-147	469.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR34280931_k127_268276_2	330214.NIDE3712	7.092e-46	172.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR34280931_k127_268276_0	330214.NIDE3711	6.223e-210	655.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR34280931_k127_268276_1	330214.NIDE3705	7.015e-114	369.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	aoxB	-	1.20.2.1,1.20.9.1	ko:K08356	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.6	-	-	Molybdopterin,Molydop_binding
SRR34280931_k127_271422_41	1123367.C666_16590	1.009e-108	362.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VQA5@28216|Betaproteobacteria,2KY5B@206389|Rhodocyclales	206389|Rhodocyclales	P	FecCD transport family	-	-	-	-	-	-	-	-	-	-	-	-	FecCD
SRR34280931_k127_271422_70	330214.NIDE2189	4.259e-18	96.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR34280931_k127_271422_51	323098.Nwi_2073	2.681e-82	285.0	COG0614@1|root,COG0614@2|Bacteria,1PGUA@1224|Proteobacteria,2VG1P@28211|Alphaproteobacteria,3JXY4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR34280931_k127_271422_43	686340.Metal_1226	6.602e-103	345.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1SCEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Luciferase-like monooxygenase	luxA	-	1.14.14.3	ko:K00494	ko02020,ko02024,map02020,map02024	-	R10551	RC00080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR34280931_k127_271422_54	330214.NIDE3933	4.124e-67	237.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K01420,ko:K10914,ko:K21556,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
SRR34280931_k127_271422_7	330214.NIDE3157	8.176e-307	945.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR34280931_k127_271422_36	330214.NIDE3158	1.26e-126	410.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR34280931_k127_271422_68	330214.NIDE3160	9.145e-20	96.0	COG4378@1|root,COG4378@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
SRR34280931_k127_271422_10	330214.NIDE3162	1.927e-278	863.0	COG3850@1|root,COG4251@1|root,COG3850@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K14978	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	CHASE8,DUF3365,GAF_2,HAMP,HATPase_c,HisKA,PilJ,Response_reg,SpoIIE
SRR34280931_k127_271422_15	330214.NIDE3163	3.475e-246	767.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	frgC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,GAF_2,HTH_8,Pkinase,Response_reg,Sigma54_activat
SRR34280931_k127_271422_44	330214.NIDE3164	1.969e-95	316.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR34280931_k127_271422_1	330214.NIDE3165	0.0	1394.0	COG2183@1|root,COG2183@2|Bacteria	2|Bacteria	K	obsolete transcription factor activity, core RNA polymerase II binding	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR34280931_k127_271422_4	330214.NIDE3167	0.0	1091.0	COG3158@1|root,COG3158@2|Bacteria,3J0YF@40117|Nitrospirae	40117|Nitrospirae	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR34280931_k127_271422_52	330214.NIDE3168	1.497e-80	272.0	COG0219@1|root,COG0219@2|Bacteria	2|Bacteria	J	wobble position uridine ribose methylation	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR34280931_k127_271422_47	330214.NIDE3169	3.614e-85	283.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR34280931_k127_271422_18	330214.NIDE3170	3.444e-228	707.0	COG0012@1|root,COG0012@2|Bacteria,3J0II@40117|Nitrospirae	40117|Nitrospirae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR34280931_k127_271422_77	570268.ANBB01000047_gene3963	0.0008326	44.0	COG3903@1|root,COG3903@2|Bacteria,2H2S6@201174|Actinobacteria,4EN4B@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12
SRR34280931_k127_271422_67	330214.NIDE3749	3.478e-21	103.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3749|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_271422_26	330214.NIDE3176	3.003e-197	619.0	COG1087@1|root,COG1087@2|Bacteria,3J0J5@40117|Nitrospirae	40117|Nitrospirae	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR34280931_k127_271422_30	330214.NIDE3177	8.115e-151	481.0	COG0484@1|root,COG1948@1|root,COG0484@2|Bacteria,COG1948@2|Bacteria	2|Bacteria	L	resolution of meiotic recombination intermediates	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,ERCC4,Lsr2
SRR34280931_k127_271422_64	1255043.TVNIR_0764	6.644e-28	118.0	COG1569@1|root,COG1569@2|Bacteria,1NJ68@1224|Proteobacteria,1SAF3@1236|Gammaproteobacteria,1X25X@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
SRR34280931_k127_271422_58	933262.AXAM01000128_gene1034	4.269e-39	158.0	COG1714@1|root,COG1714@2|Bacteria,1RFCE@1224|Proteobacteria,433E9@68525|delta/epsilon subdivisions,2WXA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR34280931_k127_271422_8	330214.NIDE3178	4.288e-282	872.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR34280931_k127_271422_12	330214.NIDE3180	8.335e-264	826.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3180|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_271422_31	330214.NIDE3181	2.483e-149	478.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	yihR	GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0006082,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1902776,GO:1902777	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR34280931_k127_271422_14	330214.NIDE3182	9.428e-248	769.0	COG0205@1|root,COG0205@2|Bacteria,3J0Y1@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR34280931_k127_271422_69	1121396.KB893123_gene1077	2.942e-18	93.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,Response_reg
SRR34280931_k127_271422_48	1173026.Glo7428_2080	9.113e-85	317.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1G1Z5@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA
SRR34280931_k127_271422_76	269482.Bcep1808_6500	1.715e-07	65.0	COG0457@1|root,COG3087@1|root,COG0457@2|Bacteria,COG3087@2|Bacteria,1MVB8@1224|Proteobacteria,2VHKT@28216|Betaproteobacteria,1K2RS@119060|Burkholderiaceae	28216|Betaproteobacteria	D	cellulose synthase operon C domain protein	bscS	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_4,TPR_7,TPR_8
SRR34280931_k127_271422_21	330214.NIDE1692	4.745e-217	680.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR34280931_k127_271422_20	330214.NIDE1691	5.119e-220	692.0	COG0477@1|root,COG2814@2|Bacteria,3J0RT@40117|Nitrospirae	40117|Nitrospirae	EGP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR34280931_k127_271422_65	937777.Deipe_0069	3.526e-26	113.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_271422_0	330214.NIDE1687	0.0	1955.0	COG0841@1|root,COG0841@2|Bacteria,3J103@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR34280931_k127_271422_22	330214.NIDE1686	7.353e-216	683.0	COG0845@1|root,COG0845@2|Bacteria,3J13H@40117|Nitrospirae	40117|Nitrospirae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR34280931_k127_271422_13	330214.NIDE1685	1.552e-251	783.0	COG1538@1|root,COG1538@2|Bacteria,3J140@40117|Nitrospirae	40117|Nitrospirae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR34280931_k127_271422_42	330214.NIDE1683	4.561e-104	338.0	COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae	40117|Nitrospirae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR34280931_k127_271422_24	330214.NIDE1682	9.998e-210	657.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR34280931_k127_271422_32	330214.NIDE1681	1.206e-146	467.0	COG0805@1|root,COG0805@2|Bacteria,3J0PJ@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR34280931_k127_271422_62	330214.NIDE1680	7.305e-33	128.0	2DRP0@1|root,33CFM@2|Bacteria,3J1BN@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
SRR34280931_k127_271422_49	330214.NIDE1679	1.248e-83	280.0	COG0454@1|root,COG0456@2|Bacteria,3J1CI@40117|Nitrospirae	40117|Nitrospirae	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR34280931_k127_271422_35	330214.NIDE1678	7.292e-132	424.0	COG1214@1|root,COG1214@2|Bacteria,3J0VU@40117|Nitrospirae	40117|Nitrospirae	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR34280931_k127_271422_33	330214.NIDE1677	1.42e-141	454.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
SRR34280931_k127_271422_9	330214.NIDE1676	2.165e-281	867.0	COG1066@1|root,COG1066@2|Bacteria,3J0BP@40117|Nitrospirae	40117|Nitrospirae	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI,Lon_C
SRR34280931_k127_271422_34	330214.NIDE1675	2.372e-132	427.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.170,2.1.1.185	ko:K03218,ko:K03437,ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03016,ko03036	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR34280931_k127_271422_50	330214.NIDE1672	2.93e-83	278.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Enterotoxin_a,HTH_3,HTH_31,N_BRCA1_IG
SRR34280931_k127_271422_6	330214.NIDE1671	0.0	1024.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
SRR34280931_k127_271422_19	330214.NIDE1670	1.121e-226	707.0	COG1092@1|root,COG1092@2|Bacteria,3J0IV@40117|Nitrospirae	40117|Nitrospirae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR34280931_k127_271422_5	330214.NIDE1669	0.0	1031.0	COG3961@1|root,COG3961@2|Bacteria	2|Bacteria	GH	pyruvate decarboxylase activity	ipdC	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR34280931_k127_271422_11	330214.NIDE1666	3.207e-264	816.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
SRR34280931_k127_271422_3	240015.ACP_0709	0.0	1099.0	COG1523@1|root,COG1523@2|Bacteria,3Y3YA@57723|Acidobacteria,2JIMQ@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR34280931_k127_271422_59	264198.Reut_B5509	3.526e-37	148.0	COG0251@1|root,COG0251@2|Bacteria,1REJQ@1224|Proteobacteria,2VYGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR34280931_k127_271422_71	269482.Bcep1808_4294	5.488e-17	84.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VKN4@28216|Betaproteobacteria,1K579@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_271422_61	330214.NIDE1655	1.895e-33	129.0	28ZVQ@1|root,2ZMK7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_271422_38	330214.NIDE1654	2.089e-125	408.0	COG0345@1|root,COG0345@2|Bacteria,3J0N8@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR34280931_k127_271422_23	330214.NIDE1653	8.539e-216	672.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
SRR34280931_k127_271422_46	330214.NIDE1651	6.984e-87	287.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR34280931_k127_271422_27	330214.NIDE1649	1.037e-183	580.0	2AAUK@1|root,3107C@2|Bacteria,3J1E0@40117|Nitrospirae	40117|Nitrospirae	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR34280931_k127_271422_16	330214.NIDE1648	8.635e-246	771.0	COG3014@1|root,COG3014@2|Bacteria,3J14B@40117|Nitrospirae	40117|Nitrospirae	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
SRR34280931_k127_271422_39	330214.NIDE1647	4.335e-114	370.0	COG3417@1|root,COG3417@2|Bacteria,3J16N@40117|Nitrospirae	40117|Nitrospirae	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
SRR34280931_k127_271422_40	330214.NIDE1646	5.964e-113	367.0	2EUFJ@1|root,33MXU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR34280931_k127_271422_17	330214.NIDE1644	1.935e-241	752.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
SRR34280931_k127_271422_2	330214.NIDE1643	0.0	1245.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR34280931_k127_271422_72	1125700.HMPREF9195_00695	3.384e-12	70.0	COG4456@1|root,COG4456@2|Bacteria,2J962@203691|Spirochaetes	203691|Spirochaetes	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
SRR34280931_k127_277466_27	330214.NIDE2141	1.594e-79	267.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,Mu-transpos_C,rve
SRR34280931_k127_277466_40	196367.JNFG01000202_gene2492	1.663e-22	100.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VUG3@28216|Betaproteobacteria,1K72W@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
SRR34280931_k127_277466_42	671143.DAMO_0637	1.01e-13	70.0	COG3549@1|root,COG3549@2|Bacteria,2NRMI@2323|unclassified Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SRR34280931_k127_277466_44	1122243.KB903805_gene2316	2.461e-05	49.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1S9WR@1236|Gammaproteobacteria,3NSCW@468|Moraxellaceae	1236|Gammaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SRR34280931_k127_277466_43	1162668.LFE_0125	2.145e-06	55.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR34280931_k127_277466_41	706587.Desti_2842	6.116e-14	76.0	2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_277466_36	330214.NIDE0331	8.18e-49	178.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
SRR34280931_k127_277466_20	330214.NIDE0330	2.202e-111	363.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SRR34280931_k127_277466_29	330214.NIDE0329	5.649e-70	243.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR34280931_k127_277466_17	330214.NIDE0326	7.11e-157	498.0	COG1611@1|root,COG1611@2|Bacteria,3J169@40117|Nitrospirae	40117|Nitrospirae	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR34280931_k127_277466_3	330214.NIDE0325	2.52e-285	880.0	COG1236@1|root,COG1236@2|Bacteria,3J0FD@40117|Nitrospirae	40117|Nitrospirae	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
SRR34280931_k127_277466_8	330214.NIDE0324	1.06e-225	704.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR34280931_k127_277466_9	330214.NIDE0322	1.917e-216	677.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR34280931_k127_277466_33	330214.NIDE0321	2.913e-65	225.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR34280931_k127_277466_10	330214.NIDE0320	1.406e-202	635.0	COG0404@1|root,COG0404@2|Bacteria,3J11R@40117|Nitrospirae	40117|Nitrospirae	H	Aminomethyltransferase folate-binding domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR34280931_k127_277466_25	330214.NIDE0319	1.467e-96	317.0	COG0494@1|root,COG0494@2|Bacteria,3J0TN@40117|Nitrospirae	40117|Nitrospirae	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR34280931_k127_277466_26	330214.NIDE0317	2.2e-84	284.0	COG3663@1|root,COG3663@2|Bacteria	2|Bacteria	L	G/U mismatch-specific uracil-DNA glycosylase activity	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR34280931_k127_277466_23	330214.NIDE0316	9.447e-102	337.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE0316|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_277466_22	330214.NIDE0315	2.767e-106	353.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_4062,iEcDH1_1363.EcDH1_4215	PfkB
SRR34280931_k127_277466_15	330214.NIDE0314	2.019e-167	530.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR34280931_k127_277466_0	330214.NIDE0312	0.0	1814.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,3J0XT@40117|Nitrospirae	40117|Nitrospirae	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR34280931_k127_277466_1	330214.NIDE0310	0.0	1025.0	COG1053@1|root,COG1053@2|Bacteria,3J0ZM@40117|Nitrospirae	40117|Nitrospirae	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR34280931_k127_277466_16	330214.NIDE0308	1.983e-165	530.0	COG0457@1|root,COG0666@1|root,COG0457@2|Bacteria,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	GO:0000122,GO:0000139,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001190,GO:0001568,GO:0001570,GO:0001666,GO:0001837,GO:0001932,GO:0001934,GO:0001944,GO:0001947,GO:0002009,GO:0002011,GO:0002193,GO:0002376,GO:0002682,GO:0002683,GO:0003007,GO:0003143,GO:0003151,GO:0003157,GO:0003158,GO:0003160,GO:0003169,GO:0003170,GO:0003171,GO:0003174,GO:0003176,GO:0003177,GO:0003179,GO:0003180,GO:0003181,GO:0003183,GO:0003184,GO:0003188,GO:0003190,GO:0003192,GO:0003197,GO:0003198,GO:0003203,GO:0003205,GO:0003206,GO:0003207,GO:0003208,GO:0003209,GO:0003213,GO:0003214,GO:0003222,GO:0003229,GO:0003230,GO:0003231,GO:0003241,GO:0003250,GO:0003252,GO:0003256,GO:0003272,GO:0003273,GO:0003279,GO:0003281,GO:0003330,GO:0003332,GO:0003344,GO:0003348,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005912,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006725,GO:0006807,GO:0006928,GO:0006950,GO:0006955,GO:0006996,GO:0007049,GO:0007050,GO:0007154,GO:0007162,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007275,GO:0007368,GO:0007389,GO:0007399,GO:0007507,GO:0007517,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008593,GO:0009058,GO:0009059,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010002,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010594,GO:0010596,GO:0010604,GO:0010605,GO:0010611,GO:0010614,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010646,GO:0010647,GO:0010648,GO:0010717,GO:0010718,GO:0010720,GO:0010721,GO:0010810,GO:0010812,GO:0010830,GO:0010832,GO:0010941,GO:0010942,GO:0012505,GO:0014013,GO:0014014,GO:0014015,GO:0014031,GO:0014706,GO:0014741,GO:0014743,GO:0016020,GO:0016043,GO:0016070,GO:0016202,GO:0016324,GO:0016477,GO:0016525,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019827,GO:0019899,GO:0022008,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030031,GO:0030054,GO:0030154,GO:0030155,GO:0030234,GO:0030278,GO:0030279,GO:0030334,GO:0030335,GO:0030336,GO:0030510,GO:0030513,GO:0030514,GO:0030855,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0031984,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032354,GO:0032501,GO:0032502,GO:0032774,GO:0032870,GO:0032879,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0034698,GO:0035050,GO:0035051,GO:0035148,GO:0035239,GO:0035265,GO:0035295,GO:0035886,GO:0035924,GO:0036003,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0040009,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0042127,GO:0042175,GO:0042221,GO:0042325,GO:0042327,GO:0042692,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043235,GO:0043408,GO:0043410,GO:0043502,GO:0043535,GO:0043537,GO:0043565,GO:0043618,GO:0043620,GO:0044057,GO:0044085,GO:0044087,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044782,GO:0045177,GO:0045445,GO:0045446,GO:0045595,GO:0045596,GO:0045597,GO:0045661,GO:0045662,GO:0045667,GO:0045668,GO:0045685,GO:0045686,GO:0045687,GO:0045747,GO:0045765,GO:0045786,GO:0045844,GO:0045892,GO:0045893,GO:0045926,GO:0045927,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0045967,GO:0046425,GO:0046427,GO:0046483,GO:0046578,GO:0046579,GO:0046620,GO:0046622,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048634,GO:0048636,GO:0048638,GO:0048639,GO:0048644,GO:0048646,GO:0048699,GO:0048710,GO:0048711,GO:0048713,GO:0048715,GO:0048729,GO:0048731,GO:0048738,GO:0048762,GO:0048844,GO:0048845,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0050922,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051056,GO:0051057,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051145,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051272,GO:0051674,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0055001,GO:0055006,GO:0055008,GO:0055010,GO:0055021,GO:0055023,GO:0055024,GO:0055025,GO:0060039,GO:0060043,GO:0060045,GO:0060251,GO:0060253,GO:0060255,GO:0060271,GO:0060284,GO:0060317,GO:0060379,GO:0060411,GO:0060412,GO:0060415,GO:0060419,GO:0060420,GO:0060421,GO:0060429,GO:0060485,GO:0060537,GO:0060548,GO:0060560,GO:0060562,GO:0060837,GO:0060840,GO:0060841,GO:0060842,GO:0060843,GO:0060947,GO:0060948,GO:0060956,GO:0060973,GO:0060976,GO:0060977,GO:0060979,GO:0060982,GO:0061061,GO:0061311,GO:0061314,GO:0061371,GO:0061383,GO:0061384,GO:0061418,GO:0061419,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070167,GO:0070168,GO:0070372,GO:0070374,GO:0070482,GO:0070848,GO:0070887,GO:0070925,GO:0071310,GO:0071363,GO:0071371,GO:0071372,GO:0071453,GO:0071456,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0072132,GO:0072358,GO:0072359,GO:0080090,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090101,GO:0090257,GO:0090287,GO:0090288,GO:0090304,GO:0097084,GO:0097150,GO:0097159,GO:0097659,GO:0098588,GO:0098590,GO:0098727,GO:0098772,GO:0098791,GO:0098827,GO:0120031,GO:0120036,GO:0140110,GO:1901201,GO:1901213,GO:1901342,GO:1901343,GO:1901360,GO:1901362,GO:1901363,GO:1901522,GO:1901532,GO:1901533,GO:1901576,GO:1901861,GO:1901863,GO:1902337,GO:1902339,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1903053,GO:1903054,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903531,GO:1903670,GO:1903671,GO:1903706,GO:1903707,GO:1904747,GO:1904748,GO:1904892,GO:1904894,GO:1905314,GO:1905456,GO:1905457,GO:1990837,GO:2000026,GO:2000027,GO:2000112,GO:2000113,GO:2000136,GO:2000137,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000209,GO:2000736,GO:2000737,GO:2000811,GO:2000826,GO:2000973,GO:2000974,GO:2001026,GO:2001027,GO:2001141	-	ko:K06867,ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Ank_2,Ank_3,Ank_4,Ank_5
SRR34280931_k127_277466_13	330214.NIDE0307	1.334e-192	608.0	COG4269@1|root,COG4269@2|Bacteria	2|Bacteria	T	membrane	yjgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF898
SRR34280931_k127_277466_12	330214.NIDE0306	1.26e-192	619.0	COG4783@1|root,COG4783@2|Bacteria,3J19Q@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR34280931_k127_277466_18	330214.NIDE0305	1.065e-137	438.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE0305|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_277466_4	330214.NIDE0304	6.605e-280	868.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3J11K@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR34280931_k127_277466_5	330214.NIDE0303	1.969e-276	855.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR34280931_k127_277466_2	330214.NIDE0302	8.529e-290	893.0	COG0621@1|root,COG0621@2|Bacteria,3J0CD@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRR34280931_k127_277466_21	330214.NIDE0301	2.003e-109	354.0	COG0663@1|root,COG0663@2|Bacteria,3J121@40117|Nitrospirae	40117|Nitrospirae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR34280931_k127_277466_14	330214.NIDE0299	1.571e-181	569.0	COG0548@1|root,COG0548@2|Bacteria,3J0H3@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR34280931_k127_277466_6	330214.NIDE0298	1.196e-268	830.0	COG1220@1|root,COG1220@2|Bacteria,3J0XE@40117|Nitrospirae	40117|Nitrospirae	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR34280931_k127_277466_24	330214.NIDE0297	3.834e-100	331.0	COG5405@1|root,COG5405@2|Bacteria,3J10R@40117|Nitrospirae	40117|Nitrospirae	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR34280931_k127_277466_32	1144275.COCOR_03386	7.728e-66	236.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR34280931_k127_277466_7	330214.NIDE0295	1.245e-268	830.0	COG1206@1|root,COG1206@2|Bacteria,3J0WT@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR34280931_k127_277466_11	330214.NIDE0294	4.802e-195	609.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
SRR34280931_k127_279593_32	330214.NIDE3049	2.099e-17	81.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR34280931_k127_279593_2	330214.NIDE3050	0.0	1190.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR34280931_k127_279593_24	330214.NIDE3051	3.335e-72	251.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE3051|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_279593_3	330214.NIDE3052	0.0	1179.0	COG0745@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_279593_10	330214.NIDE3053	3.213e-179	565.0	COG0739@1|root,COG0739@2|Bacteria,3J16B@40117|Nitrospirae	40117|Nitrospirae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR34280931_k127_279593_6	330214.NIDE3054	2.027e-300	924.0	COG0638@1|root,COG0638@2|Bacteria	2|Bacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR34280931_k127_279593_15	330214.NIDE3055	4.255e-134	428.0	COG0638@1|root,COG0638@2|Bacteria	2|Bacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR34280931_k127_279593_11	330214.NIDE3056	2.327e-159	505.0	COG0638@1|root,COG0638@2|Bacteria	2|Bacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR34280931_k127_279593_5	330214.NIDE3057	1.596e-305	942.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119,6.3.1.19	ko:K13571,ko:K20814	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR34280931_k127_279593_4	330214.NIDE3058	0.0	1124.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR34280931_k127_279593_20	330214.NIDE3059	7.221e-87	291.0	COG0352@1|root,COG0352@2|Bacteria,3J0QS@40117|Nitrospirae	40117|Nitrospirae	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE2	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR34280931_k127_279593_13	330214.NIDE3060	7.349e-157	496.0	COG2022@1|root,COG2022@2|Bacteria,3J0EI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR34280931_k127_279593_30	330214.NIDE3061	5.308e-29	116.0	COG2104@1|root,COG2104@2|Bacteria,3J1CM@40117|Nitrospirae	40117|Nitrospirae	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_279593_31	667014.Thein_1111	2.432e-26	115.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GHB5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR34280931_k127_279593_8	330214.NIDE3064	6.043e-273	843.0	COG0793@1|root,COG0793@2|Bacteria,3J09Y@40117|Nitrospirae	40117|Nitrospirae	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
SRR34280931_k127_279593_9	330214.NIDE3065	7.691e-216	674.0	COG4942@1|root,COG4942@2|Bacteria,3J0SP@40117|Nitrospirae	40117|Nitrospirae	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR34280931_k127_279593_12	330214.NIDE3066	5.271e-158	503.0	COG2177@1|root,COG2177@2|Bacteria,3J18Q@40117|Nitrospirae	40117|Nitrospirae	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR34280931_k127_279593_16	330214.NIDE3067	2.019e-129	415.0	COG2884@1|root,COG2884@2|Bacteria,3J139@40117|Nitrospirae	40117|Nitrospirae	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR34280931_k127_279593_25	330214.NIDE3068	4.633e-65	224.0	COG0792@1|root,COG0792@2|Bacteria,3J1ER@40117|Nitrospirae	40117|Nitrospirae	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR34280931_k127_279593_18	330214.NIDE3069	1.316e-114	374.0	COG0164@1|root,COG0164@2|Bacteria,3J0P5@40117|Nitrospirae	40117|Nitrospirae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR34280931_k127_279593_23	330214.NIDE3070	1.206e-72	246.0	COG0335@1|root,COG0335@2|Bacteria,3J0MJ@40117|Nitrospirae	40117|Nitrospirae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR34280931_k127_279593_14	330214.NIDE3071	4.583e-151	479.0	COG0336@1|root,COG0336@2|Bacteria,3J0JN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR34280931_k127_279593_22	330214.NIDE3072	1.048e-84	283.0	COG0806@1|root,COG0806@2|Bacteria	2|Bacteria	J	ribosome binding	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR34280931_k127_279593_27	330214.NIDE3073	4.853e-52	185.0	COG0228@1|root,COG0228@2|Bacteria,3J0UI@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR34280931_k127_279593_7	330214.NIDE3074	1.508e-277	855.0	COG0541@1|root,COG0541@2|Bacteria,3J0DT@40117|Nitrospirae	40117|Nitrospirae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR34280931_k127_279593_28	330214.NIDE3076	7.855e-44	161.0	29W29@1|root,30HKU@2|Bacteria,3J1EN@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
SRR34280931_k127_279593_1	330214.NIDE3077	0.0	1272.0	COG0556@1|root,COG0556@2|Bacteria,3J0FS@40117|Nitrospirae	40117|Nitrospirae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR34280931_k127_279593_26	330214.NIDE2249	5.144e-62	220.0	COG1974@1|root,COG1974@2|Bacteria,3J1C0@40117|Nitrospirae	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response)	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR34280931_k127_279593_17	330214.NIDE2248	1.245e-116	389.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR34280931_k127_279593_0	330214.NIDE2247	0.0	1382.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	2|Bacteria	L	DNA-directed DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR34280931_k127_279593_19	330214.NIDE3183	3.824e-93	310.0	COG1047@1|root,COG1047@2|Bacteria	2|Bacteria	O	modulation by symbiont of host adenylate cyclase-mediated signal transduction	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR34280931_k127_279593_21	1000565.METUNv1_01551	8.956e-85	297.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVA7@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR34280931_k127_279593_29	330214.NIDE3327	1.325e-43	162.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR34280931_k127_29419_3	330214.NIDE0462	6.671e-19	86.0	COG4949@1|root,COG4949@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
SRR34280931_k127_29419_0	330214.NIDE0460	7.058e-114	374.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	2|Bacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR34280931_k127_29419_1	330214.NIDE0458	2.698e-37	139.0	COG3041@1|root,COG3041@2|Bacteria	2|Bacteria	S	endonuclease activity	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
SRR34280931_k127_296688_20	330214.NIDE3236	7.449e-21	91.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
SRR34280931_k127_296688_18	330214.NIDE3257	2.381e-33	130.0	COG2906@1|root,COG2906@2|Bacteria	2|Bacteria	P	2 iron, 2 sulfur cluster binding	bfd	GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
SRR34280931_k127_296688_12	330214.NIDE3258	2.141e-94	314.0	COG0655@1|root,COG0655@2|Bacteria,3J192@40117|Nitrospirae	40117|Nitrospirae	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR34280931_k127_296688_13	330214.NIDE3261	6.566e-83	277.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR34280931_k127_296688_6	330214.NIDE3262	5.914e-246	767.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria	2|Bacteria	M	cellular water homeostasis	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,TM_helix,cNMP_binding
SRR34280931_k127_296688_0	330214.NIDE3263	0.0	1410.0	COG0317@1|root,COG0317@2|Bacteria,3J0CX@40117|Nitrospirae	40117|Nitrospirae	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR34280931_k127_296688_3	330214.NIDE3264	0.0	1007.0	COG0608@1|root,COG0608@2|Bacteria,3J0PF@40117|Nitrospirae	40117|Nitrospirae	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR34280931_k127_296688_1	330214.NIDE3266	0.0	1249.0	COG3808@1|root,COG3808@2|Bacteria	2|Bacteria	C	hydrogen-translocating pyrophosphatase activity	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR34280931_k127_296688_7	330214.NIDE3268	1.982e-245	762.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR34280931_k127_296688_5	330214.NIDE3269	5.776e-266	821.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR34280931_k127_296688_10	330214.NIDE3271	2.847e-174	548.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SRR34280931_k127_296688_4	330214.NIDE3272	4.529e-271	835.0	COG3391@1|root,COG3391@2|Bacteria,3J19W@40117|Nitrospirae	40117|Nitrospirae	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR34280931_k127_296688_16	330214.NIDE3273	1.408e-38	146.0	COG1826@1|root,COG1826@2|Bacteria,3J1A4@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR34280931_k127_296688_11	330214.NIDE3274	2.196e-163	517.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3274|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_296688_2	330214.NIDE3276	0.0	1200.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
SRR34280931_k127_296688_9	330214.NIDE3278	4.093e-208	646.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SRR34280931_k127_300490_3	330214.NIDE2766	3.861e-57	198.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR34280931_k127_300490_2	330214.NIDE2765	1.432e-82	275.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	cycH	-	3.4.21.105	ko:K02200,ko:K04018,ko:K19225,ko:K20543,ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.55.3	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SRR34280931_k127_300490_1	330214.NIDE2764	6.508e-120	387.0	COG1648@1|root,COG1648@2|Bacteria	2|Bacteria	H	precorrin-2 dehydrogenase activity	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
SRR34280931_k127_300490_4	330214.NIDE2763	1.987e-54	192.0	COG0011@1|root,COG0011@2|Bacteria,3J0QD@40117|Nitrospirae	40117|Nitrospirae	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR34280931_k127_301047_6	330214.NIDE2676	7.477e-39	147.0	COG4095@1|root,COG4095@2|Bacteria,3J0UA@40117|Nitrospirae	40117|Nitrospirae	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
SRR34280931_k127_301047_7	330214.NIDE2677	7.821e-33	127.0	COG0227@1|root,COG0227@2|Bacteria,3J0VJ@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR34280931_k127_301047_4	330214.NIDE2678	2.404e-49	184.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
SRR34280931_k127_301047_8	1123355.JHYO01000016_gene1888	2.467e-10	64.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2UBSS@28211|Alphaproteobacteria,36YV4@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_301047_2	330214.NIDE2896	7.584e-131	446.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
SRR34280931_k127_301047_0	330214.NIDE0887	1.725e-181	601.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR34280931_k127_301047_1	330214.NIDE0885	9.323e-161	516.0	COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_301047_9	768671.ThimaDRAFT_2214	1.225e-06	61.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Lipase_GDSL_2,Metallophos,SASA,SLH
SRR34280931_k127_301047_3	1283300.ATXB01000001_gene1498	5.205e-55	206.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria,1XGA2@135618|Methylococcales	135618|Methylococcales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
SRR34280931_k127_301047_5	134676.ACPL_5635	6.556e-43	162.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR34280931_k127_304242_7	330214.NIDE2536	0.0	1037.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR34280931_k127_304242_44	330214.NIDE2535	7.178e-130	419.0	COG0664@1|root,COG0664@2|Bacteria,3J18E@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR34280931_k127_304242_26	330214.NIDE2534	1.814e-193	606.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	aniA	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR34280931_k127_304242_28	330214.NIDE2530	2.396e-190	603.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR34280931_k127_304242_42	330214.NIDE2529	1.361e-131	426.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,NB-ARC,PG_binding_1,TPR_10,TniB
SRR34280931_k127_304242_74	330214.NIDE2528	1.201e-54	195.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR34280931_k127_304242_29	330214.NIDE2527	1.045e-185	584.0	COG2048@1|root,COG2048@2|Bacteria,3J175@40117|Nitrospirae	40117|Nitrospirae	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00241,ko:K03389	ko00020,ko00190,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00356,M00357,M00374,M00376,M00563,M00567	R02164,R04540,R11928,R11931,R11943,R11944	RC00011,RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SRR34280931_k127_304242_37	330214.NIDE2525	1.668e-161	512.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
SRR34280931_k127_304242_14	330214.NIDE2524	9.183e-279	860.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.6.1.1,1.8.1.4	ko:K00322,ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map00760,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00112,R00209,R01221,R01698,R03815,R07618,R08549	RC00001,RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR34280931_k127_304242_83	497964.CfE428DRAFT_5644	1.347e-39	167.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia	2|Bacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
SRR34280931_k127_304242_4	330214.NIDE2522	0.0	1334.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,3J10M@40117|Nitrospirae	40117|Nitrospirae	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR34280931_k127_304242_56	330214.NIDE2521	3.74e-91	308.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
SRR34280931_k127_304242_9	330214.NIDE2519	1.136e-298	918.0	COG1690@1|root,COG1690@2|Bacteria,3J0X0@40117|Nitrospirae	40117|Nitrospirae	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR34280931_k127_304242_69	330214.NIDE2518	9.24e-60	224.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR34280931_k127_304242_25	330214.NIDE2517	1.564e-197	618.0	COG0479@1|root,COG0479@2|Bacteria,3J14K@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10
SRR34280931_k127_304242_21	330214.NIDE2516	1.231e-230	716.0	COG0006@1|root,COG0006@2|Bacteria,3J0R0@40117|Nitrospirae	40117|Nitrospirae	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR34280931_k127_304242_0	330214.NIDE2515	0.0	2057.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2,DUF3971,DUF748
SRR34280931_k127_304242_22	330214.NIDE2514	3.477e-227	709.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
SRR34280931_k127_304242_80	1123371.ATXH01000006_gene868	3.095e-46	179.0	COG0681@1|root,COG0681@2|Bacteria,2GH8B@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR34280931_k127_304242_10	330214.NIDE2498	4.481e-291	901.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	CW_binding_1,Lactamase_B
SRR34280931_k127_304242_50	330214.NIDE2497	4.743e-110	357.0	COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae	40117|Nitrospirae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR34280931_k127_304242_53	330214.NIDE2495	1.442e-97	321.0	2F2MT@1|root,33ZTN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_67	330214.NIDE2494	9.488e-63	217.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	-
SRR34280931_k127_304242_90	370438.PTH_0500	3.016e-13	71.0	COG2002@1|root,COG2002@2|Bacteria,1W48M@1239|Firmicutes,255K1@186801|Clostridia	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR34280931_k127_304242_89	1125863.JAFN01000001_gene2725	7.778e-26	111.0	COG1848@1|root,COG1848@2|Bacteria,1RFD9@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR34280931_k127_304242_16	330214.NIDE2493	5.48e-250	774.0	COG1355@1|root,COG1355@2|Bacteria,3J0U4@40117|Nitrospirae	40117|Nitrospirae	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR34280931_k127_304242_39	330214.NIDE2492	1.81e-153	486.0	2ANS9@1|root,31DS7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_36	330214.NIDE2491	1.038e-172	544.0	28MYQ@1|root,2ZB5K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_45	330214.NIDE2490	3.688e-127	407.0	29ZH8@1|root,30MGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_20	330214.NIDE2489	4.318e-236	735.0	28MEN@1|root,2ZASA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_23	330214.NIDE2488	2.24e-215	672.0	28II6@1|root,2Z8JB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_6	330214.NIDE2487	0.0	1152.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
SRR34280931_k127_304242_79	330214.NIDE2486	1.739e-47	173.0	2EGJW@1|root,33AC1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_304242_68	330214.NIDE2482	2.981e-60	208.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR34280931_k127_304242_33	330214.NIDE2481	2.906e-175	552.0	COG0489@1|root,COG0489@2|Bacteria,3J0Z6@40117|Nitrospirae	40117|Nitrospirae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
SRR34280931_k127_304242_32	330214.NIDE2480	9.933e-177	554.0	COG1398@1|root,COG1398@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR34280931_k127_304242_55	330214.NIDE2479	3.139e-92	306.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR34280931_k127_304242_2	330214.NIDE2475	0.0	1664.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512,iYO844.BSU37780	Aldedh,Pro_dh
SRR34280931_k127_304242_51	330214.NIDE2473	5.814e-108	354.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE2473|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR34280931_k127_304242_57	330214.NIDE2471	1.055e-89	302.0	COG0132@1|root,COG0132@2|Bacteria,3J0SI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR34280931_k127_304242_78	1120973.AQXL01000121_gene104	6.232e-48	179.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,278BH@186823|Alicyclobacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR34280931_k127_304242_12	330214.NIDE2469	1.135e-285	879.0	COG0439@1|root,COG0439@2|Bacteria,3J0AJ@40117|Nitrospirae	40117|Nitrospirae	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR34280931_k127_304242_54	330214.NIDE2468	1.129e-95	316.0	COG0511@1|root,COG0511@2|Bacteria,3J0PI@40117|Nitrospirae	40117|Nitrospirae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR34280931_k127_304242_47	330214.NIDE2467	4.826e-114	369.0	COG0231@1|root,COG0231@2|Bacteria,3J0JC@40117|Nitrospirae	40117|Nitrospirae	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR34280931_k127_304242_59	330214.NIDE2466	5.1e-83	278.0	COG0757@1|root,COG0757@2|Bacteria,3J199@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR34280931_k127_304242_58	330214.NIDE2465	1.509e-89	300.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	2.7.11.1	ko:K14949,ko:K20543	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	1.B.55.3	-	-	DUF560,EcsC,Glyco_transf_41,HyaE,NfrA_C,Sulfotransfer_3,TPR_16
SRR34280931_k127_304242_24	330214.NIDE2464	8.147e-212	663.0	COG0452@1|root,COG0452@2|Bacteria,3J0GK@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR34280931_k127_304242_41	330214.NIDE2462	3.282e-138	441.0	COG0194@1|root,COG0194@2|Bacteria,3J0JT@40117|Nitrospirae	40117|Nitrospirae	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR34280931_k127_304242_40	330214.NIDE2461	8.374e-152	487.0	COG1561@1|root,COG1561@2|Bacteria,3J0QJ@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR34280931_k127_304242_48	330214.NIDE2460	4.134e-111	364.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	40117|Nitrospirae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR34280931_k127_304242_8	330214.NIDE2459	5.312e-304	940.0	COG2262@1|root,COG2262@2|Bacteria,3J0AE@40117|Nitrospirae	40117|Nitrospirae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR34280931_k127_304242_30	330214.NIDE2458	5.834e-180	569.0	COG0533@1|root,COG0533@2|Bacteria,3J0I3@40117|Nitrospirae	40117|Nitrospirae	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR34280931_k127_304242_3	330214.NIDE2457	0.0	1564.0	COG0542@1|root,COG0542@2|Bacteria,3J0B4@40117|Nitrospirae	40117|Nitrospirae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR34280931_k127_304242_35	330214.NIDE2456	6.141e-174	548.0	COG0061@1|root,COG0061@2|Bacteria,3J0HS@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR34280931_k127_304242_15	330214.NIDE2455	9.444e-270	832.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	preT	-	1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00528,ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R10159,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,GXGXG,Pyr_redox_2,Pyr_redox_3
SRR34280931_k127_304242_11	330214.NIDE2454	1.089e-289	897.0	COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae	40117|Nitrospirae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR34280931_k127_304242_60	330214.NIDE2453	5.976e-78	265.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR34280931_k127_304242_18	330214.NIDE2451	3.039e-245	758.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.gltA	Citrate_synt
SRR34280931_k127_304242_72	330214.NIDE2447	1.323e-57	201.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR34280931_k127_304242_19	330214.NIDE2445	3.914e-245	758.0	COG0349@1|root,COG0349@2|Bacteria	2|Bacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR34280931_k127_304242_46	330214.NIDE2444	1.365e-120	388.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	cbpA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363	-	ko:K05516,ko:K05801,ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000,ko03036,ko03110	3.A.1.27.4,3.A.1.27.5	-	-	DnaJ,DnaJ_C
SRR34280931_k127_304242_27	1288494.EBAPG3_190	3.143e-193	610.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,2VH3A@28216|Betaproteobacteria,371YR@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
SRR34280931_k127_304242_13	330214.NIDE2442	1.889e-284	876.0	COG0281@1|root,COG0281@2|Bacteria,3J0WV@40117|Nitrospirae	40117|Nitrospirae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR34280931_k127_304242_1	330214.NIDE2440	0.0	2056.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,3J0HX@40117|Nitrospirae	40117|Nitrospirae	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR34280931_k127_304242_52	330214.NIDE2439	5.263e-103	337.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR34280931_k127_304242_66	330214.NIDE2438	6.641e-66	226.0	COG2905@1|root,COG2905@2|Bacteria,3J0UW@40117|Nitrospirae	40117|Nitrospirae	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR34280931_k127_304242_43	330214.NIDE2425	1.849e-130	426.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR34280931_k127_304242_73	330214.NIDE2422	8.247e-56	200.0	COG3065@1|root,COG3065@2|Bacteria	2|Bacteria	M	identical protein binding	slp	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
SRR34280931_k127_304242_75	330214.NIDE2437	1.468e-51	190.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE2437|-	T	phosphorelay signal transduction system	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR34280931_k127_304242_62	330214.NIDE2428	1.079e-70	243.0	COG3431@1|root,COG3431@2|Bacteria,3J1A3@40117|Nitrospirae	40117|Nitrospirae	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
SRR34280931_k127_304242_61	330214.NIDE2426	4.595e-76	262.0	COG0745@1|root,COG0745@2|Bacteria,3J0JU@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07664	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR34280931_k127_304242_31	330214.NIDE2420	7.546e-179	564.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR34280931_k127_304242_5	330214.NIDE2419	0.0	1238.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR34280931_k127_304242_34	247490.KSU1_B0327	4.175e-174	562.0	COG0581@1|root,COG0581@2|Bacteria,2IZJV@203682|Planctomycetes	203682|Planctomycetes	P	phosphate ABC transporter	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR34280931_k127_304242_38	330214.NIDE2417	5.255e-154	489.0	COG1117@1|root,COG1117@2|Bacteria,3J0EU@40117|Nitrospirae	40117|Nitrospirae	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR34280931_k127_304242_71	330214.NIDE2416	1.421e-58	204.0	COG0704@1|root,COG0704@2|Bacteria,3J0M6@40117|Nitrospirae	40117|Nitrospirae	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR34280931_k127_305539_80	903818.KI912269_gene527	4.452e-43	165.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.183,2.3.1.82	ko:K03823,ko:K18816	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	br01600,ko00000,ko00001,ko01000,ko01504	-	-	-	Acetyltransf_1,Methyltransf_25
SRR34280931_k127_305539_59	443255.SCLAV_2727	5.816e-100	335.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR34280931_k127_305539_38	330214.NIDE1715	1.795e-146	473.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,VCBS
SRR34280931_k127_305539_93	313595.P700755_003528	0.0001724	51.0	2BYIR@1|root,2ZFPD@2|Bacteria,4P8T4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_305539_91	767434.Fraau_0615	5.964e-07	62.0	2DSJN@1|root,33GEV@2|Bacteria,1NJQT@1224|Proteobacteria	1224|Proteobacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF2778,PG_binding_1
SRR34280931_k127_305539_65	330214.NIDE1715	1.593e-88	312.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,VCBS
SRR34280931_k127_305539_34	330214.NIDE1715	6.997e-164	546.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,VCBS
SRR34280931_k127_305539_90	886293.Sinac_1341	3.592e-07	53.0	COG3209@1|root,COG3209@2|Bacteria,2IY61@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,RHS_repeat
SRR34280931_k127_305539_16	330214.NIDE1711	1.333e-218	681.0	COG1015@1|root,COG1015@2|Bacteria	2|Bacteria	G	phosphopentomutase activity	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_0465,iNRG857_1313.NRG857_22165	Metalloenzyme
SRR34280931_k127_305539_46	330214.NIDE1710	2.729e-127	415.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR34280931_k127_305539_28	330214.NIDE1709	2.386e-186	587.0	COG1559@1|root,COG1559@2|Bacteria,3J0IR@40117|Nitrospirae	40117|Nitrospirae	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR34280931_k127_305539_81	1121346.KB899860_gene364	2.302e-37	150.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,26XDH@186822|Paenibacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR34280931_k127_305539_1	330214.NIDE1707	0.0	1629.0	COG0013@1|root,COG0013@2|Bacteria,3J0D3@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR34280931_k127_305539_75	330214.NIDE1706	2.696e-66	232.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT4	-	RecX
SRR34280931_k127_305539_17	330214.NIDE1705	7.231e-218	678.0	COG0468@1|root,COG0468@2|Bacteria,3J0C1@40117|Nitrospirae	40117|Nitrospirae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR34280931_k127_305539_68	330214.NIDE3078	5.59e-81	278.0	COG1514@1|root,COG1514@2|Bacteria,3J1B8@40117|Nitrospirae	40117|Nitrospirae	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR34280931_k127_305539_19	330214.NIDE3079	2.041e-213	668.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3J1AS@40117|Nitrospirae	40117|Nitrospirae	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
SRR34280931_k127_305539_35	330214.NIDE3081	4.296e-153	484.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR34280931_k127_305539_61	330214.NIDE3087	5.129e-93	311.0	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	ycbK	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Peptidase_M15_2,Peptidase_M15_3
SRR34280931_k127_305539_12	330214.NIDE3088	2.108e-227	712.0	COG2204@1|root,COG2204@2|Bacteria,3J107@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_305539_45	330214.NIDE3091	3.251e-128	411.0	COG2197@1|root,COG2197@2|Bacteria,3J12Q@40117|Nitrospirae	40117|Nitrospirae	K	Product type r regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR34280931_k127_305539_0	330214.NIDE3092	0.0	1773.0	COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
SRR34280931_k127_305539_73	330214.NIDE3093	2.667e-71	244.0	COG1051@1|root,COG1051@2|Bacteria,3J1FA@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR34280931_k127_305539_41	330214.NIDE3094	1.299e-141	454.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR34280931_k127_305539_55	330214.NIDE3095	1.412e-106	349.0	COG1750@1|root,COG1750@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lon_C,SdrD_B
SRR34280931_k127_305539_2	330214.NIDE3096	0.0	1435.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
SRR34280931_k127_305539_11	330214.NIDE3097	2.802e-228	712.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Haemagg_act,PATR
SRR34280931_k127_305539_3	330214.NIDE3098	0.0	1077.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,POTRA_2,ShlB
SRR34280931_k127_305539_26	880073.Calab_3483	1.336e-200	635.0	COG3033@1|root,COG3033@2|Bacteria,2NNZV@2323|unclassified Bacteria	2|Bacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR34280931_k127_305539_9	330214.NIDE3100	4.626e-295	920.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR34280931_k127_305539_23	330214.NIDE3101	4.144e-207	649.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR34280931_k127_305539_48	330214.NIDE3102	5.51e-125	404.0	COG1024@1|root,COG1024@2|Bacteria,3J1EP@40117|Nitrospirae	40117|Nitrospirae	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K13767,ko:K13816	ko00071,ko00362,ko01100,ko01120,ko01212,ko02020,ko02024,map00071,map00362,map01100,map01120,map01212,map02020,map02024	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR34280931_k127_305539_22	330214.NIDE3103	6.983e-210	659.0	COG1250@1|root,COG1250@2|Bacteria,3J1F9@40117|Nitrospirae	40117|Nitrospirae	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH_N
SRR34280931_k127_305539_15	330214.NIDE3104	2.4e-221	693.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR34280931_k127_305539_7	330214.NIDE3105	4.013e-307	947.0	COG0318@1|root,COG0318@2|Bacteria,3J12Y@40117|Nitrospirae	40117|Nitrospirae	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR34280931_k127_305539_51	330214.NIDE3106	1.872e-119	389.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR34280931_k127_305539_58	330214.NIDE3109	1.42e-102	336.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	5.1.99.1	ko:K05606,ko:K17315	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko02010,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map02010	M00373,M00375,M00376,M00605,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	Glyoxalase_3,Glyoxalase_4
SRR34280931_k127_305539_18	330214.NIDE3110	1.917e-214	668.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR34280931_k127_305539_30	330214.NIDE3111	1.478e-178	563.0	COG0179@1|root,COG0179@2|Bacteria,3J1AP@40117|Nitrospirae	40117|Nitrospirae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR34280931_k127_305539_47	330214.NIDE3112	1.455e-125	410.0	COG0461@1|root,COG0461@2|Bacteria	2|Bacteria	F	orotate phosphoribosyltransferase activity	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR34280931_k127_305539_27	330214.NIDE3113	1.264e-199	624.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR34280931_k127_305539_24	330214.NIDE3114	1.362e-205	643.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR34280931_k127_305539_29	330214.NIDE3115	9.195e-181	572.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR34280931_k127_305539_21	330214.NIDE3116	5.186e-211	665.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_2215	Thiolase_C,Thiolase_N
SRR34280931_k127_305539_32	330214.NIDE3117	3.065e-171	545.0	COG1250@1|root,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	mmgB	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
SRR34280931_k127_305539_5	330214.NIDE3118	1.897e-316	972.0	COG1884@1|root,COG1884@2|Bacteria	2|Bacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR34280931_k127_305539_37	330214.NIDE3119	8.759e-150	477.0	COG0491@1|root,COG0491@2|Bacteria,3J1C9@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR34280931_k127_305539_79	338966.Ppro_0388	6.42e-48	179.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,43UUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR34280931_k127_305539_6	330214.NIDE3121	5.194e-312	960.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	mccB	-	2.1.3.15,6.4.1.3,6.4.1.4,6.4.1.5	ko:K01969,ko:K13778,ko:K15052	ko00280,ko00281,ko00720,ko01100,ko01200,map00280,map00281,map00720,map01100,map01200	M00036,M00376	R01859,R03494,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3290	Carboxyl_trans
SRR34280931_k127_305539_53	330214.NIDE3122	3.263e-111	365.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR34280931_k127_305539_43	330214.NIDE3123	1.65e-140	455.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	mvaB	GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224	4.1.3.4,6.4.1.4	ko:K01640,ko:K01968	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R04138,R08090	RC00367,RC00502,RC00503,RC00942,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3293	HMGL-like
SRR34280931_k127_305539_57	330214.NIDE3124	2.447e-103	342.0	COG1703@1|root,COG1703@2|Bacteria	2|Bacteria	E	isobutyryl-CoA mutase activity	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR34280931_k127_305539_13	330214.NIDE3125	6.765e-227	711.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	prpD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
SRR34280931_k127_305539_44	330214.NIDE3126	1.098e-138	447.0	COG2513@1|root,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
SRR34280931_k127_305539_62	985665.HPL003_16225	7.513e-93	318.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,26RV3@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR34280931_k127_305539_8	330214.NIDE3128	2.475e-299	925.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR34280931_k127_305539_4	330214.NIDE3129	0.0	1021.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR34280931_k127_305539_36	330214.NIDE3131	9.764e-151	482.0	COG0668@1|root,COG0668@2|Bacteria,3J0YK@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR34280931_k127_305539_14	330214.NIDE3133	1.415e-224	704.0	2C8FN@1|root,2ZBER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_305539_20	330214.NIDE3134	2.393e-212	667.0	COG0457@1|root,COG0457@2|Bacteria,3J1CG@40117|Nitrospirae	330214.NIDE3134|-	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_305539_78	330214.NIDE2529	3.744e-51	195.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,NB-ARC,PG_binding_1,TPR_10,TniB
SRR34280931_k127_305539_63	330214.NIDE3144	2.187e-92	306.0	COG1974@1|root,COG1974@2|Bacteria,3J1C0@40117|Nitrospirae	40117|Nitrospirae	K	Represses a number of genes involved in the response to DNA damage (SOS response)	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR34280931_k127_305539_50	330214.NIDE3146	4.856e-120	390.0	2C2AA@1|root,2ZAYY@2|Bacteria,3J1CT@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	TraT
SRR34280931_k127_305539_52	330214.NIDE3147	1.367e-113	371.0	2C2AA@1|root,2ZAYY@2|Bacteria,3J1CT@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	TraT
SRR34280931_k127_305539_31	330214.NIDE3148	3.098e-176	559.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	modC	-	2.10.1.1,3.6.3.29,3.6.3.55	ko:K02017,ko:K02018,ko:K03750,ko:K15497	ko00790,ko01100,ko02010,map00790,map01100,map02010	M00189,M00423	R09735,R10531	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR34280931_k127_305539_71	237368.SCABRO_03151	1.687e-75	260.0	COG4149@1|root,COG4149@2|Bacteria,2J01Z@203682|Planctomycetes	203682|Planctomycetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR34280931_k127_305539_86	330214.NIDE3150	8.603e-26	107.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	modE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
SRR34280931_k127_305539_88	1246995.AFR_33285	1.453e-15	82.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4DEAM@85008|Micromonosporales	201174|Actinobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR34280931_k127_305539_33	330214.NIDE3148	3.186e-170	542.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	modC	-	2.10.1.1,3.6.3.29,3.6.3.55	ko:K02017,ko:K02018,ko:K03750,ko:K15497	ko00790,ko01100,ko02010,map00790,map01100,map02010	M00189,M00423	R09735,R10531	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR34280931_k127_305539_70	237368.SCABRO_03151	3.216e-76	262.0	COG4149@1|root,COG4149@2|Bacteria,2J01Z@203682|Planctomycetes	203682|Planctomycetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR34280931_k127_305539_87	330214.NIDE3150	2.618e-24	103.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	modE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
SRR34280931_k127_305539_49	330214.NIDE3152	3.977e-124	403.0	COG0725@1|root,COG0725@2|Bacteria,3J18Z@40117|Nitrospirae	40117|Nitrospirae	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR34280931_k127_305539_10	330214.NIDE3153	4.201e-257	803.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR34280931_k127_305539_69	330214.NIDE3155	5.116e-79	273.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR34280931_k127_305539_39	330214.NIDE3156	4.033e-145	470.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria,3J13A@40117|Nitrospirae	40117|Nitrospirae	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
SRR34280931_k127_305539_40	909663.KI867150_gene158	2.292e-143	482.0	COG4772@1|root,COG4772@2|Bacteria,1MVMV@1224|Proteobacteria,42MYZ@68525|delta/epsilon subdivisions,2WJBZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR34280931_k127_305539_66	1297865.APJD01000020_gene74	2.124e-83	291.0	COG2041@1|root,COG2041@2|Bacteria,1N9NH@1224|Proteobacteria,2UGW7@28211|Alphaproteobacteria,3K5HS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR34280931_k127_305539_67	330214.NIDE3811	1.514e-82	296.0	COG1269@1|root,COG1269@2|Bacteria,3J156@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR34280931_k127_305539_60	330214.NIDE3810	3.965e-95	328.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	celD	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Mig-14,TPR_16
SRR34280931_k127_305539_56	330214.NIDE3809	2.477e-106	355.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	walW	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_305539_42	330214.NIDE3812	7.773e-141	477.0	COG0457@1|root,COG0457@2|Bacteria,3J17M@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR34280931_k127_305539_72	1121441.AUCX01000007_gene1053	3.128e-72	250.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42NRB@68525|delta/epsilon subdivisions,2WJHF@28221|Deltaproteobacteria,2MA2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	HP	PFAM ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR34280931_k127_316904_0	330214.NIDE3939	3.083e-262	820.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PilZ,Sigma54_activat
SRR34280931_k127_316904_1	330214.NIDE3940	1.65e-67	231.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE3940|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_318570_25	330214.NIDE3299	1.622e-174	550.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
SRR34280931_k127_318570_23	330214.NIDE3300	2.107e-189	592.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_318570_1	330214.NIDE3303	0.0	1169.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR34280931_k127_318570_38	330214.NIDE3306	1.942e-139	445.0	COG2322@1|root,COG2322@2|Bacteria	2|Bacteria	S	membrane	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR34280931_k127_318570_20	330214.NIDE3307	2.596e-194	608.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	crtF	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.210,2.1.1.304,2.1.1.333	ko:K09846,ko:K13604,ko:K21460	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	-	R07521,R07524,R07527,R07529,R07533,R07535,R09063	RC00003,RC01662,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
SRR34280931_k127_318570_30	330214.NIDE3308	4.533e-164	517.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_318570_15	330214.NIDE3309	1.409e-236	738.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
SRR34280931_k127_318570_24	330214.NIDE3311	4.129e-184	578.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_318570_27	330214.NIDE3312	7.2e-172	541.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_318570_0	330214.NIDE3313	0.0	3292.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR34280931_k127_318570_2	330214.NIDE3314	0.0	1132.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR34280931_k127_318570_19	330214.NIDE3315	2.623e-202	634.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Cu_amine_oxidN1,F5_F8_type_C,IgGFc_binding,PKD
SRR34280931_k127_318570_14	330214.NIDE3318	7.099e-241	752.0	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRR34280931_k127_318570_3	330214.NIDE3319	0.0	1114.0	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K12146,ko:K15836	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR34280931_k127_318570_17	330214.NIDE3321	2.226e-208	654.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_318570_42	330214.NIDE3322	6.487e-127	417.0	COG1136@1|root,COG1136@2|Bacteria,3J10N@40117|Nitrospirae	2|Bacteria	V	Evidence 2b Function of strongly homologous gene	hrtA	-	-	ko:K02003,ko:K09810,ko:K09814	ko02010,map02010	M00255,M00257,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
SRR34280931_k127_318570_28	330214.NIDE3323	9.25e-171	541.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR34280931_k127_318570_10	330214.NIDE3324	1.352e-274	852.0	COG1538@1|root,COG1538@2|Bacteria,3J0N2@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRR34280931_k127_318570_33	330214.NIDE3325	8.365e-154	490.0	COG0457@1|root,COG0457@2|Bacteria,3J1EU@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR34280931_k127_318570_55	330214.NIDE3327	1.885e-58	205.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR34280931_k127_318570_52	330214.NIDE3332	1.073e-77	264.0	COG1134@1|root,COG1134@2|Bacteria,3J142@40117|Nitrospirae	2|Bacteria	GM	Evidence 2b Function of strongly homologous gene	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_318570_60	1403819.BATR01000002_gene40	7.153e-09	61.0	COG1134@1|root,COG1134@2|Bacteria,46SDX@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_318570_41	330214.NIDE3334	1.344e-129	417.0	COG3751@1|root,COG3751@2|Bacteria	2|Bacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
SRR34280931_k127_318570_32	330214.NIDE3335	4.37e-159	502.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01421,ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
SRR34280931_k127_318570_39	330214.NIDE3338	2.509e-138	441.0	COG1131@1|root,COG1131@2|Bacteria,3J116@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_318570_35	330214.NIDE3339	1.153e-145	462.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K03532,ko:K15876	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko02000	5.A.3.4	-	-	Cytochrom_NNT,Cytochrome_C7
SRR34280931_k127_318570_57	335543.Sfum_3074	7.054e-39	151.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MQKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
SRR34280931_k127_318570_12	330214.NIDE3341	6.163e-264	814.0	COG0303@1|root,COG0303@2|Bacteria,3J0MX@40117|Nitrospirae	40117|Nitrospirae	H	Probable molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR34280931_k127_318570_16	330214.NIDE3342	1.341e-212	660.0	COG0489@1|root,COG0489@2|Bacteria,3J10K@40117|Nitrospirae	40117|Nitrospirae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
SRR34280931_k127_318570_21	330214.NIDE3343	7.459e-194	606.0	COG0805@1|root,COG0805@2|Bacteria,3J0PJ@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR34280931_k127_318570_8	330214.NIDE3344	1.723e-290	897.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,3J0VW@40117|Nitrospirae	40117|Nitrospirae	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_318570_40	330214.NIDE3346	1.164e-133	430.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_318570_13	330214.NIDE3347	9.098e-245	765.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRR34280931_k127_318570_5	330214.NIDE3348	1.341e-310	957.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR34280931_k127_318570_7	330214.NIDE3349	2.938e-292	910.0	COG4249@1|root,COG4249@2|Bacteria,3J0QX@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14
SRR34280931_k127_318570_49	330214.NIDE3350	6.437e-93	307.0	COG2010@1|root,COG2010@2|Bacteria,3J17C@40117|Nitrospirae	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
SRR34280931_k127_318570_34	330214.NIDE3351	1.025e-145	467.0	COG1426@1|root,COG1426@2|Bacteria,3J1CJ@40117|Nitrospirae	40117|Nitrospirae	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR34280931_k127_318570_43	330214.NIDE3352	1.908e-125	404.0	COG3063@1|root,COG3063@2|Bacteria,3J0V4@40117|Nitrospirae	40117|Nitrospirae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
SRR34280931_k127_318570_22	330214.NIDE3353	1.785e-192	601.0	COG0524@1|root,COG0524@2|Bacteria,3J0ZT@40117|Nitrospirae	40117|Nitrospirae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR34280931_k127_318570_31	330214.NIDE3354	2.366e-160	509.0	COG0005@1|root,COG0005@2|Bacteria,3J0HC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR34280931_k127_318570_29	330214.NIDE3355	4.03e-169	537.0	COG0324@1|root,COG0324@2|Bacteria,3J0KS@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR34280931_k127_318570_4	330214.NIDE3356	8.306e-317	978.0	COG0323@1|root,COG0323@2|Bacteria,3J0GN@40117|Nitrospirae	40117|Nitrospirae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR34280931_k127_318570_36	330214.NIDE3357	2.313e-142	454.0	COG1729@1|root,COG1729@2|Bacteria,3J0RE@40117|Nitrospirae	40117|Nitrospirae	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
SRR34280931_k127_318570_9	330214.NIDE3358	1.685e-283	879.0	COG1729@1|root,COG4372@1|root,COG1729@2|Bacteria,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	ko:K01991,ko:K02557,ko:K07161,ko:K07484	ko02026,ko02030,ko02040,map02026,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.18	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,TPR_6,zf-IS66
SRR34280931_k127_318570_37	330214.NIDE3359	7.855e-141	452.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	2|Bacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR34280931_k127_318570_6	330214.NIDE3360	3.561e-293	900.0	COG0823@1|root,COG0823@2|Bacteria,3J0U9@40117|Nitrospirae	40117|Nitrospirae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR34280931_k127_318570_18	330214.NIDE3361	1.592e-206	649.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR34280931_k127_318570_51	330214.NIDE3362	5.983e-84	280.0	COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae	40117|Nitrospirae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
SRR34280931_k127_318570_44	330214.NIDE3363	8.413e-123	396.0	COG0811@1|root,COG0811@2|Bacteria,3J0PX@40117|Nitrospirae	40117|Nitrospirae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
SRR34280931_k127_322301_1	105559.Nwat_0325	2.77e-24	102.0	COG2159@1|root,COG2159@2|Bacteria,1R73N@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR34280931_k127_322301_5	518766.Rmar_0728	1.881e-07	64.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
SRR34280931_k127_322301_3	105559.Nwat_0324	9.396e-17	94.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	3D,PG_binding_1,VanY
SRR34280931_k127_322301_0	335283.Neut_1623	1.125e-57	223.0	COG3023@1|root,COG3023@2|Bacteria,1PZDY@1224|Proteobacteria,2W3RG@28216|Betaproteobacteria	28216|Betaproteobacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_322301_6	1089546.AQUI01000002_gene4254	3.071e-06	58.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,2I319@201174|Actinobacteria,4089H@622450|Actinopolysporales	201174|Actinobacteria	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1
SRR34280931_k127_322301_2	1038866.KB902778_gene7315	1.646e-18	96.0	2BZNS@1|root,34AU2@2|Bacteria,1P67Z@1224|Proteobacteria,2U2V2@28211|Alphaproteobacteria,3JWXI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_322301_4	391625.PPSIR1_00165	7.984e-15	83.0	COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2Z267@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
SRR34280931_k127_349492_7	1123279.ATUS01000001_gene2720	1.848e-18	98.0	COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zonular occludens toxin (Zot)	-	-	-	ko:K10954	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	Zot
SRR34280931_k127_349492_8	1245471.PCA10_28800	9.159e-08	60.0	2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2523
SRR34280931_k127_349492_3	330214.NIDE0337	3.56e-97	328.0	COG2946@1|root,COG2946@2|Bacteria	2|Bacteria	L	Replication initiation factor	nicK	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
SRR34280931_k127_349492_0	56780.SYN_00017	0.0	1933.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42SZ0@68525|delta/epsilon subdivisions,2WPIR@28221|Deltaproteobacteria,2MQGQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
SRR34280931_k127_349492_4	290318.Cvib_0624	2.446e-84	290.0	292DC@1|root,2ZPXP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_349492_5	1054213.HMPREF9946_00656	4.579e-37	145.0	2E8F9@1|root,332TM@2|Bacteria,1NPFT@1224|Proteobacteria,2UM53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_349492_2	879212.DespoDRAFT_02341	0.0	1343.0	COG1743@1|root,COG1743@2|Bacteria,1MW7U@1224|Proteobacteria,42RFU@68525|delta/epsilon subdivisions,2WNXH@28221|Deltaproteobacteria,2MM76@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF1156)	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	DUF1156
SRR34280931_k127_349492_1	879212.DespoDRAFT_02342	0.0	1582.0	COG1483@1|root,COG1483@2|Bacteria,1MX1G@1224|Proteobacteria,42VAG@68525|delta/epsilon subdivisions,2WREB@28221|Deltaproteobacteria,2MNSQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF499)	-	-	-	ko:K06922	-	-	-	-	ko00000	-	-	-	DUF499
SRR34280931_k127_349492_6	214092.5832489	4.237e-19	91.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,41HUX@629|Yersinia	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_354183_2	187303.BN69_2016	4.805e-08	58.0	COG5562@1|root,COG5562@2|Bacteria,1N9UF@1224|Proteobacteria,2U97S@28211|Alphaproteobacteria,3707I@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
SRR34280931_k127_354183_1	1173264.KI913949_gene4146	1.111e-91	306.0	COG0262@1|root,COG0262@2|Bacteria,1G7CT@1117|Cyanobacteria,1HHRG@1150|Oscillatoriales	1117|Cyanobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR34280931_k127_354183_0	330214.NIDE4295	8.756e-96	315.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
SRR34280931_k127_370497_8	330214.NIDE2353	2.262e-82	275.0	COG0840@1|root,COG0840@2|Bacteria,3J0N9@40117|Nitrospirae	40117|Nitrospirae	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR34280931_k127_370497_5	330214.NIDE2354	7.25e-93	306.0	COG0835@1|root,COG0835@2|Bacteria,3J0PG@40117|Nitrospirae	40117|Nitrospirae	NT	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR34280931_k127_370497_4	330214.NIDE2356	1.434e-148	471.0	COG1291@1|root,COG1291@2|Bacteria,3J0KF@40117|Nitrospirae	40117|Nitrospirae	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
SRR34280931_k127_370497_3	330214.NIDE2357	8.927e-151	478.0	COG1360@1|root,COG1360@2|Bacteria,3J0MN@40117|Nitrospirae	40117|Nitrospirae	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR34280931_k127_370497_2	330214.NIDE2359	8.779e-176	557.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRR34280931_k127_370497_9	330214.NIDE2360	8.099e-74	249.0	COG0745@1|root,COG0745@2|Bacteria,3J18A@40117|Nitrospirae	40117|Nitrospirae	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR34280931_k127_370497_0	330214.NIDE2361	0.0	1219.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,3J0BG@40117|Nitrospirae	2|Bacteria	NT	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	cheA	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
SRR34280931_k127_370497_6	330214.NIDE2362	8.931e-93	306.0	COG0835@1|root,COG0835@2|Bacteria,3J0PG@40117|Nitrospirae	40117|Nitrospirae	NT	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR34280931_k127_370497_1	330214.NIDE2363	0.0	1020.0	COG0840@1|root,COG1017@1|root,COG2202@1|root,COG0840@2|Bacteria,COG1017@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	bdlA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Globin,MCPsignal,PAS_3,PAS_9
SRR34280931_k127_370497_7	330214.NIDE2364	3.939e-90	297.0	COG2322@1|root,COG2322@2|Bacteria,3J1D2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR34280931_k127_377446_0	450851.PHZ_c1809	2.6e-129	428.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2KI09@204458|Caulobacterales	204458|Caulobacterales	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR34280931_k127_377446_1	1038859.AXAU01000031_gene4153	1.077e-108	361.0	COG3832@1|root,COG3832@2|Bacteria,1R428@1224|Proteobacteria,2U6AP@28211|Alphaproteobacteria,3K3YI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR34280931_k127_377446_2	1380355.JNIJ01000007_gene3289	7.438e-74	257.0	COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria,2U6EZ@28211|Alphaproteobacteria,3K3ZG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR34280931_k127_404060_1	330214.NIDE1696	8.198e-140	446.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR34280931_k127_404060_2	517417.Cpar_1358	2.713e-112	389.0	2E9D7@1|root,333KS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_404060_5	391612.CY0110_14590	4.297e-22	109.0	COG0412@1|root,COG0412@2|Bacteria,1GGA6@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR34280931_k127_404060_3	261292.Nit79A3_2268	3.893e-89	303.0	COG4782@1|root,COG4782@2|Bacteria,1N9HN@1224|Proteobacteria	1224|Proteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR34280931_k127_404060_4	261292.Nit79A3_2267	9.282e-66	233.0	2E84E@1|root,332I4@2|Bacteria,1NFMY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_417747_13	330214.NIDE0681	1.749e-128	414.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_417747_2	330214.NIDE0678	0.0	1583.0	COG2217@1|root,COG2217@2|Bacteria,3J0CY@40117|Nitrospirae	40117|Nitrospirae	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR34280931_k127_417747_15	330214.NIDE0677	1.672e-122	394.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbA	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	iEcSMS35_1347.EcSMS35_4241	DSBA
SRR34280931_k127_417747_19	330214.NIDE0676	1.482e-94	315.0	COG3065@1|root,COG3065@2|Bacteria,3J1BB@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
SRR34280931_k127_417747_5	330214.NIDE0639	0.0	1083.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR34280931_k127_417747_29	330214.NIDE0636	3.656e-30	120.0	COG2452@1|root,COG2452@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,HTH_17
SRR34280931_k127_417747_4	330214.NIDE0635	0.0	1162.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR34280931_k127_417747_21	330214.NIDE0633	5.733e-80	269.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR34280931_k127_417747_7	330214.NIDE0632	2.154e-248	771.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
SRR34280931_k127_417747_10	330214.NIDE0631	3.063e-221	687.0	COG4313@1|root,COG4313@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_417747_17	330214.NIDE0629	7.736e-101	331.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	yneN	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR34280931_k127_417747_12	330214.NIDE0628	1.71e-162	524.0	COG0810@1|root,COG0810@2|Bacteria,3J0U0@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR34280931_k127_417747_28	330214.NIDE0625	4.659e-40	152.0	28QX7@1|root,2ZDCB@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_417747_11	330214.NIDE0624	2.527e-204	639.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE0624|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_417747_0	330214.NIDE0623	0.0	1741.0	COG0653@1|root,COG0653@2|Bacteria,3J0E5@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR34280931_k127_417747_8	330214.NIDE0616	1.038e-230	717.0	COG1565@1|root,COG1565@2|Bacteria,3J0P0@40117|Nitrospirae	40117|Nitrospirae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR34280931_k127_417747_23	330214.NIDE0615	3.883e-71	241.0	COG0838@1|root,COG0838@2|Bacteria,3J0MS@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR34280931_k127_417747_18	330214.NIDE0614	5.12e-99	325.0	COG0377@1|root,COG0377@2|Bacteria,3J11S@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR34280931_k127_417747_3	330214.NIDE0613	0.0	1164.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,3J0FM@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
SRR34280931_k127_417747_16	330214.NIDE0612	1.058e-104	343.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
SRR34280931_k127_417747_6	330214.NIDE0611	2.524e-280	863.0	COG1894@1|root,COG1894@2|Bacteria,3J0WX@40117|Nitrospirae	40117|Nitrospirae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR34280931_k127_417747_1	330214.NIDE0609	0.0	1593.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	40117|Nitrospirae	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR34280931_k127_417747_9	330214.NIDE0608	1.449e-221	688.0	COG1005@1|root,COG1005@2|Bacteria,3J0E2@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR34280931_k127_417747_14	330214.NIDE0607	7.745e-124	396.0	COG1143@1|root,COG1143@2|Bacteria,3J0N0@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR34280931_k127_430946_25	330214.NIDE1896	6.725e-25	103.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR34280931_k127_430946_20	330214.NIDE1895	2.271e-54	191.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	hesB	-	-	ko:K07390,ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016,ko03029,ko03110	-	-	-	Fe-S_biosyn,Glutaredoxin,NifU,Rhodanese
SRR34280931_k127_430946_15	330214.NIDE1894	3.525e-114	368.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
SRR34280931_k127_430946_5	330214.NIDE1893	9.602e-220	687.0	COG0116@1|root,COG0116@2|Bacteria	2|Bacteria	L	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
SRR34280931_k127_430946_4	330214.NIDE1892	7.35e-292	900.0	COG0380@1|root,COG0380@2|Bacteria,3J10Z@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR34280931_k127_430946_3	330214.NIDE1891	0.0	1133.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
SRR34280931_k127_430946_0	330214.NIDE1890	0.0	1469.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR34280931_k127_430946_16	330214.NIDE1889	2.714e-83	276.0	COG0229@1|root,COG0229@2|Bacteria,3J17K@40117|Nitrospirae	40117|Nitrospirae	C	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR34280931_k127_430946_9	1278073.MYSTI_02311	3.287e-148	480.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR34280931_k127_430946_14	330214.NIDE1885	7.37e-116	377.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	MtrB_PioB,OMP_b-brl
SRR34280931_k127_430946_17	330214.NIDE1884	1.417e-82	280.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	dsbL	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
SRR34280931_k127_430946_13	330214.NIDE1882	4.969e-129	417.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	kynB	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR34280931_k127_430946_8	330214.NIDE1881	3.915e-169	539.0	COG1850@1|root,COG1850@2|Bacteria,3J16S@40117|Nitrospirae	40117|Nitrospirae	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
SRR34280931_k127_430946_7	330214.NIDE1879	6.638e-206	648.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
SRR34280931_k127_430946_2	330214.NIDE1878	0.0	1197.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_430946_11	330214.NIDE1875	1.099e-135	439.0	COG0450@1|root,COG0450@2|Bacteria,3J0T1@40117|Nitrospirae	40117|Nitrospirae	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR34280931_k127_430946_19	330214.NIDE1874	9.881e-63	218.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
SRR34280931_k127_430946_1	330214.NIDE1873	0.0	1386.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
SRR34280931_k127_430946_26	237609.PSAKL28_33220	1.049e-10	64.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,1S25M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRR34280931_k127_430946_18	926550.CLDAP_10490	2.505e-81	282.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yfnG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR34280931_k127_430946_10	330214.NIDE1045	7.377e-139	445.0	28JAC@1|root,2Z956@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_430946_21	1056816.JAFQ01000004_gene2304	1.462e-38	151.0	COG0125@1|root,COG0125@2|Bacteria,2HHZA@201174|Actinobacteria,4G1V4@85025|Nocardiaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR34280931_k127_430946_22	561175.KB894097_gene271	2.419e-35	142.0	COG0847@1|root,COG0847@2|Bacteria,2IDVR@201174|Actinobacteria	201174|Actinobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR34280931_k127_430946_12	1463934.JOCF01000094_gene857	2.68e-135	441.0	COG1533@1|root,2Z9QC@2|Bacteria,2GTQ0@201174|Actinobacteria	201174|Actinobacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_434459_4	1282360.ABAC460_13555	1.199e-14	82.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HCBP_related,HemolysinCabind,PPC,Peptidase_M10_C
SRR34280931_k127_434459_3	1296990.H845_3432	3.873e-40	149.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,2JPM7@204441|Rhodospirillales	28211|Alphaproteobacteria	L	Transposase mutator type	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR34280931_k127_434459_5	1296990.H845_3698	1.185e-11	64.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR34280931_k127_434459_2	1121479.AUBS01000015_gene1260	2.706e-42	163.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR34280931_k127_434459_6	935565.JAEM01000100_gene623	1.965e-05	48.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,2PW4V@265|Paracoccus	28211|Alphaproteobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
SRR34280931_k127_434459_7	412597.AEPN01000025_gene337	4.649e-05	48.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,2U7TH@28211|Alphaproteobacteria,2PX6A@265|Paracoccus	28211|Alphaproteobacteria	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
SRR34280931_k127_434459_1	391593.RCCS2_17801	1.234e-68	259.0	COG2931@1|root,COG2931@2|Bacteria,1PFEK@1224|Proteobacteria,2UPPH@28211|Alphaproteobacteria,2P51F@2433|Roseobacter	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR34280931_k127_434459_0	391593.RCCS2_02503	3.94e-86	293.0	2B5JQ@1|root,31YEN@2|Bacteria,1RCTT@1224|Proteobacteria,2U6E2@28211|Alphaproteobacteria,2P3QR@2433|Roseobacter	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR34280931_k127_472609_2	909943.HIMB100_00003610	8.18e-15	84.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,4BRBR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_475725_13	330214.NIDE1274	1.603e-165	529.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR34280931_k127_475725_6	330214.NIDE0907	6.699e-248	781.0	COG4249@1|root,COG4249@2|Bacteria,3J0QX@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14
SRR34280931_k127_475725_18	330214.NIDE0906	4.594e-129	421.0	COG0382@1|root,COG0382@2|Bacteria,3J0TY@40117|Nitrospirae	40117|Nitrospirae	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR34280931_k127_475725_9	330214.NIDE0905	5.762e-215	668.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K02305,ko:K07152	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko03029	3.D.4.10	-	-	Cytochrom_C,PA14,SCO1-SenC
SRR34280931_k127_475725_11	330214.NIDE0904	1.248e-179	562.0	2ERPD@1|root,33J8R@2|Bacteria	2|Bacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
SRR34280931_k127_475725_14	330214.NIDE0903	4.393e-159	501.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR34280931_k127_475725_21	330214.NIDE0902	1.244e-121	391.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	soxD	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
SRR34280931_k127_475725_1	330214.NIDE0901	0.0	1199.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR34280931_k127_475725_7	330214.NIDE0899	8.385e-245	756.0	COG1290@1|root,COG1290@2|Bacteria,3J0Q6@40117|Nitrospirae	40117|Nitrospirae	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR34280931_k127_475725_10	330214.NIDE0898	9.335e-192	600.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K03886	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00151,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR34280931_k127_475725_15	330214.NIDE0897	1.903e-154	489.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Cytochrom_C,EB_dh
SRR34280931_k127_475725_2	330214.NIDE0896	0.0	1126.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR34280931_k127_475725_22	330214.NIDE0895	5.14e-117	377.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR34280931_k127_475725_30	330214.NIDE0892	8.792e-68	233.0	29E6W@1|root,3014W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_475725_8	330214.NIDE0891	2.628e-228	706.0	COG0535@1|root,COG0535@2|Bacteria,3J0X6@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
SRR34280931_k127_475725_17	330214.NIDE0890	1.492e-134	440.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
SRR34280931_k127_475725_0	330214.NIDE0889	0.0	1201.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	kpsD	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Caps_synth_GfcC,Poly_export,SLBB
SRR34280931_k127_475725_4	330214.NIDE0888	2.081e-319	982.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	wzi	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi,PAP2
SRR34280931_k127_475725_32	1379698.RBG1_1C00001G1728	1.072e-53	204.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR34280931_k127_475725_23	1379698.RBG1_1C00001G1729	2.174e-99	337.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	ntdA	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.104	ko:K18653	-	-	R10698	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_475725_20	237368.SCABRO_01456	2.011e-123	404.0	COG0022@1|root,COG0022@2|Bacteria,2IYRX@203682|Planctomycetes	203682|Planctomycetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR34280931_k127_475725_27	588581.Cpap_1407	1.244e-88	305.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia	186801|Clostridia	C	dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR34280931_k127_475725_29	1379698.RBG1_1C00001G1732	1.016e-69	243.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Bac_transf,Glyco_tranf_2_3,Glycos_transf_2
SRR34280931_k127_475725_33	74546.PMT9312_1203	1.224e-48	184.0	COG0500@1|root,COG0500@2|Bacteria,1GGJB@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_475725_24	1379698.RBG1_1C00001G1732	1.365e-98	335.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Bac_transf,Glyco_tranf_2_3,Glycos_transf_2
SRR34280931_k127_475725_38	223926.28805208	2.321e-18	95.0	COG1216@1|root,COG1216@2|Bacteria,1N4UY@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_475725_37	1064535.MELS_0817	1.045e-25	122.0	2DZXJ@1|root,32VMJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_475725_35	349161.Dred_3098	1.999e-36	156.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,2605U@186807|Peptococcaceae	186801|Clostridia	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR34280931_k127_475725_25	330214.NIDE0876	5.049e-95	314.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K10936,ko:K16079	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.4.2.1	-	-	OMP_b-brl
SRR34280931_k127_475725_39	446462.Amir_3670	3.593e-10	64.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612,ko:K16035	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09853,R09858	RC00055,RC02840	ko00000,ko00001,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR34280931_k127_475725_5	330214.NIDE0872	2.15e-312	964.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,3J12F@40117|Nitrospirae	40117|Nitrospirae	P	TrkA-N domain	-	-	-	ko:K03455,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.37	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR34280931_k127_475725_36	326297.Sama_1635	2.936e-30	134.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06871,ko:K09858	-	-	-	-	ko00000	-	-	-	PRiA4_ORF3,SEC-C
SRR34280931_k127_475725_28	330214.NIDE1387	5.796e-77	267.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114	1.13.11.49	ko:K09162	-	-	-	-	ko00000,ko01000	-	-	-	Chlor_dismutase
SRR34280931_k127_475725_16	1121396.KB893080_gene898	1.593e-138	456.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2WU4G@28221|Deltaproteobacteria,2MMQM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR34280931_k127_475725_26	1265505.ATUG01000001_gene3625	5.27e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,42S73@68525|delta/epsilon subdivisions,2WNPE@28221|Deltaproteobacteria,2MPTJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR34280931_k127_476366_6	717785.HYPMC_3431	2.226e-38	149.0	2E7ZA@1|root,332DQ@2|Bacteria,1N8W6@1224|Proteobacteria,2UH44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2924
SRR34280931_k127_476366_7	670307.HYPDE_26598	2.172e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,1PWG2@1224|Proteobacteria,2VGG5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Protein of unknown function (DUF3489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3489
SRR34280931_k127_476366_9	1308866.J416_11777	4.131e-06	53.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR34280931_k127_476366_4	377629.TERTU_2697	2.216e-49	179.0	COG1669@1|root,COG1669@2|Bacteria,1RGUJ@1224|Proteobacteria,1SCI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
SRR34280931_k127_476366_0	272568.GDI0126	1.312e-167	535.0	COG1403@1|root,COG1403@2|Bacteria,1PAQC@1224|Proteobacteria,2U34W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_476366_5	272568.GDI0123	2.105e-38	149.0	COG1310@1|root,COG1310@2|Bacteria,1NBZI@1224|Proteobacteria,2UGHU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR34280931_k127_476366_1	745310.G432_18800	6.368e-143	473.0	COG0476@1|root,COG0476@2|Bacteria,1R7G7@1224|Proteobacteria,2UAZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Prokaryotic E2 family B	-	-	-	-	-	-	-	-	-	-	-	-	Prok-E2_B,ThiF
SRR34280931_k127_476366_2	272568.GDI0125	7.627e-140	455.0	2DBDI@1|root,2Z8M4@2|Bacteria,1R655@1224|Proteobacteria,2U1J5@28211|Alphaproteobacteria,2JYAY@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_476366_8	493475.GARC_1297	3.315e-07	56.0	COG0846@1|root,COG0846@2|Bacteria,1Q89F@1224|Proteobacteria,1RRI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SRR34280931_k127_476366_3	1028800.RG540_PA10370	1.496e-72	248.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,4BAQE@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR34280931_k127_495036_9	330214.NIDE2550	1.579e-104	342.0	COG0161@1|root,COG0161@2|Bacteria,3J0D9@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR34280931_k127_495036_0	330214.NIDE2551	0.0	1174.0	COG0481@1|root,COG0481@2|Bacteria,3J0D1@40117|Nitrospirae	40117|Nitrospirae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR34280931_k127_495036_12	1121403.AUCV01000042_gene126	4.679e-57	210.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR34280931_k127_495036_3	330214.NIDE2553	4.83e-204	641.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
SRR34280931_k127_495036_11	243231.GSU1896	2.649e-68	240.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR34280931_k127_495036_1	330214.NIDE2555	0.0	1080.0	COG0504@1|root,COG0504@2|Bacteria,3J0FB@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR34280931_k127_495036_8	883156.HMPREF9282_01533	1.231e-107	355.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR34280931_k127_495036_4	330214.NIDE2557	1.741e-187	589.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,3J0GG@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR34280931_k127_495036_7	330214.NIDE2558	2.514e-108	353.0	COG0558@1|root,COG0558@2|Bacteria,3J0NH@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR34280931_k127_495036_6	330214.NIDE2559	4.241e-114	372.0	COG0344@1|root,COG0344@2|Bacteria,3J0PK@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR34280931_k127_495036_10	330214.NIDE2560	2.662e-100	330.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C
SRR34280931_k127_495036_2	330214.NIDE2561	6.299e-261	811.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_495036_5	330214.NIDE2562	5.546e-183	574.0	COG0480@1|root,COG0480@2|Bacteria,3J0WU@40117|Nitrospirae	40117|Nitrospirae	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR34280931_k127_495785_3	330214.NIDE1694	1.415e-19	91.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Zeta_toxin
SRR34280931_k127_495785_0	349521.HCH_01122	2.542e-54	204.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,1S37I@1236|Gammaproteobacteria,1XP52@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
SRR34280931_k127_495785_1	452471.Aasi_0851	6.293e-22	106.0	COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,47QS2@768503|Cytophagia	976|Bacteroidetes	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,Tox-ODYAM1,U-box
SRR34280931_k127_53465_31	1123053.AUDG01000006_gene3846	1.815e-27	121.0	COG0299@1|root,COG0299@2|Bacteria,1NIYA@1224|Proteobacteria,1SIJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR34280931_k127_53465_26	402881.Plav_3318	1.989e-38	159.0	COG4106@1|root,COG4106@2|Bacteria,1R02P@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR34280931_k127_53465_24	1121481.AUAS01000003_gene4103	7.111e-42	165.0	COG5285@1|root,COG5285@2|Bacteria,4NK9U@976|Bacteroidetes,47MVP@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR34280931_k127_53465_1	103690.17129901	2.389e-178	568.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1HR4E@1161|Nostocales	1117|Cyanobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_53465_2	373994.Riv7116_5626	2.908e-162	525.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1HN29@1161|Nostocales	1117|Cyanobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR34280931_k127_53465_5	344747.PM8797T_19979	1.001e-152	496.0	COG3356@1|root,COG3356@2|Bacteria,2J2EY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_53465_8	1382306.JNIM01000001_gene1105	9.66e-119	403.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	200795|Chloroflexi	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRR34280931_k127_53465_28	269799.Gmet_2336	4.9e-34	142.0	COG0463@1|root,COG0463@2|Bacteria,1RKGW@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_53465_7	1283300.ATXB01000001_gene1379	1.249e-124	409.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XFHT@135618|Methylococcales	135618|Methylococcales	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR34280931_k127_53465_12	1121441.AUCX01000016_gene2328	1.616e-82	285.0	COG1052@1|root,COG1052@2|Bacteria,1QVZS@1224|Proteobacteria,43A0B@68525|delta/epsilon subdivisions,2X1TR@28221|Deltaproteobacteria,2MC2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR34280931_k127_53465_4	1121904.ARBP01000005_gene4705	3.96e-157	504.0	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,47NJS@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
SRR34280931_k127_53465_19	1385512.N784_05290	1.601e-51	192.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,4HG7P@91061|Bacilli	91061|Bacilli	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR34280931_k127_53465_3	1123234.AUKI01000015_gene2296	3.58e-159	520.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_53465_18	999541.bgla_1g16700	4.742e-54	199.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,1JZUS@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR34280931_k127_53465_37	1206101.AZXC01000030_gene1912	3.845e-05	55.0	COG2334@1|root,COG2334@2|Bacteria,2GNSC@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
SRR34280931_k127_53465_27	589924.Ferp_0164	1.398e-37	152.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,245Y2@183980|Archaeoglobi	183980|Archaeoglobi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR34280931_k127_53465_10	234267.Acid_2241	7.657e-106	355.0	COG0673@1|root,COG0673@2|Bacteria,3Y754@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR34280931_k127_53465_32	317013.NY99_10700	1.704e-14	84.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR34280931_k127_53465_13	926569.ANT_06460	5.579e-64	231.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	-	2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
SRR34280931_k127_53465_16	720554.Clocl_0400	2.816e-56	203.0	COG0110@1|root,COG0110@2|Bacteria,1V2DC@1239|Firmicutes,24GM5@186801|Clostridia,3WIM1@541000|Ruminococcaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRR34280931_k127_53465_6	234267.Acid_2246	4.32e-132	428.0	COG2089@1|root,COG2089@2|Bacteria,3Y39R@57723|Acidobacteria	57723|Acidobacteria	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR34280931_k127_53465_11	234267.Acid_2240	1.478e-105	349.0	COG1028@1|root,COG1028@2|Bacteria,3Y3U1@57723|Acidobacteria	57723|Acidobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR34280931_k127_53465_20	357808.RoseRS_2381	3.995e-51	196.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,375VE@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR34280931_k127_53465_33	1120966.AUBU01000001_gene854	4.277e-13	82.0	COG1887@1|root,COG1887@2|Bacteria,4NG8F@976|Bacteroidetes,47SNK@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf,MGDG_synth
SRR34280931_k127_53465_35	866895.HBHAL_1436	1.446e-07	64.0	COG0438@1|root,COG0438@2|Bacteria,1V0JQ@1239|Firmicutes,4HE9R@91061|Bacilli,3ND62@45667|Halobacillus	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_53465_29	1144313.PMI10_01280	2.377e-30	128.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes,1IIUR@117743|Flavobacteriia,2P0G9@237|Flavobacterium	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR34280931_k127_53465_30	1122931.AUAE01000001_gene753	1.809e-27	114.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes,2FR0K@200643|Bacteroidia,230IA@171551|Porphyromonadaceae	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR34280931_k127_53465_17	518766.Rmar_1136	7.785e-56	203.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes	976|Bacteroidetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_53465_22	1303518.CCALI_02423	3.523e-46	168.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR34280931_k127_53465_15	861299.J421_3499	2.663e-60	218.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K02687	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Methyltransf_12,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31,PrmA
SRR34280931_k127_53465_34	269796.Rru_A2739	2.832e-10	72.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_53465_36	649638.Trad_0737	6.003e-06	59.0	COG3307@1|root,COG3307@2|Bacteria,1WNB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR34280931_k127_53465_0	1254432.SCE1572_00900	0.0	1127.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2YYSN@29|Myxococcales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR34280931_k127_53465_25	760568.Desku_1744	6.525e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR34280931_k127_53465_9	880072.Desac_1335	1.867e-106	369.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2MRZC@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_53465_14	234267.Acid_7807	9.381e-62	225.0	COG0726@1|root,COG0726@2|Bacteria,3Y95Z@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR34280931_k127_53465_21	330214.NIDE0880	3.03e-49	189.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR34280931_k127_540916_1	330214.NIDE2716	9.267e-79	270.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	sgaR	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR34280931_k127_540916_0	330214.NIDE2725	1.212e-235	733.0	COG0162@1|root,COG0162@2|Bacteria,3J0FX@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR34280931_k127_540916_3	330214.NIDE2726	1.884e-48	184.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
SRR34280931_k127_540916_2	330214.NIDE2727	1.551e-66	228.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR34280931_k127_553266_17	1108045.GORHZ_050_00160	6.793e-25	120.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria,2GP4N@201174|Actinobacteria,4GAPU@85026|Gordoniaceae	201174|Actinobacteria	P	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3,Rieske
SRR34280931_k127_553266_11	1218074.BAXZ01000001_gene144	9.666e-74	258.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR34280931_k127_553266_20	1242864.D187_000821	0.000587	51.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR34280931_k127_553266_8	118173.KB235914_gene3925	1.423e-124	412.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_553266_7	237368.SCABRO_01358	2.366e-126	409.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR34280931_k127_553266_15	330214.NIDE2898	3.715e-60	214.0	COG1596@1|root,COG1596@2|Bacteria,3J17R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR34280931_k127_553266_14	330214.NIDE2899	3.138e-67	237.0	COG1596@1|root,COG1596@2|Bacteria,3J17R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR34280931_k127_553266_19	1123240.ATVO01000006_gene1678	1.394e-09	62.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2UBSS@28211|Alphaproteobacteria,2K66A@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_553266_9	330214.NIDE2714	4.534e-86	291.0	COG0250@1|root,COG0250@2|Bacteria,3J17S@40117|Nitrospirae	40117|Nitrospirae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
SRR34280931_k127_553266_13	330214.NIDE2716	2.023e-71	248.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	sgaR	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR34280931_k127_553266_3	330214.NIDE2725	4.18e-228	711.0	COG0162@1|root,COG0162@2|Bacteria,3J0FX@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR34280931_k127_553266_16	330214.NIDE2726	6.752e-42	165.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
SRR34280931_k127_553266_1	330214.NIDE2727	1.38e-279	862.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR34280931_k127_553266_12	330214.NIDE2728	1.173e-71	243.0	COG0509@1|root,COG0509@2|Bacteria,3J0SD@40117|Nitrospirae	40117|Nitrospirae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR34280931_k127_553266_2	330214.NIDE2729	6.358e-260	811.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	3.2.1.51	ko:K01206,ko:K07114,ko:K07126	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04147	1.A.13.2.2,1.A.13.2.3	GH29	-	FecR
SRR34280931_k127_553266_10	330214.NIDE2730	3.561e-82	273.0	COG0105@1|root,COG0105@2|Bacteria,3J0PH@40117|Nitrospirae	40117|Nitrospirae	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR34280931_k127_553266_6	330214.NIDE2731	1.647e-185	584.0	COG0182@1|root,COG0182@2|Bacteria,3J0G0@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR34280931_k127_553266_5	330214.NIDE2732	6.408e-197	617.0	COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_553266_4	330214.NIDE2733	9.149e-210	657.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR34280931_k127_553266_0	330214.NIDE2734	3.668e-318	984.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3J0VB@40117|Nitrospirae	40117|Nitrospirae	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
SRR34280931_k127_555132_31	330214.NIDE3135	4.243e-177	574.0	COG0726@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG0726@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.156	ko:K13735,ko:K15125,ko:K15531	ko05100,ko05133,map05100,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000	-	GH8	-	DUF4347,PATR,VPEP
SRR34280931_k127_555132_79	1242864.D187_009491	4.974e-67	252.0	COG4191@1|root,COG4191@2|Bacteria,1R3RN@1224|Proteobacteria,42P11@68525|delta/epsilon subdivisions,2WJEK@28221|Deltaproteobacteria,2Z34U@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,PAS_4
SRR34280931_k127_555132_55	404380.Gbem_0065	3.122e-119	408.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,GAF,HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3,dCache_1
SRR34280931_k127_555132_36	330214.NIDE1756	1.252e-159	507.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR34280931_k127_555132_52	330214.NIDE1758	1.295e-124	403.0	COG1814@1|root,COG1814@2|Bacteria,3J16V@40117|Nitrospirae	40117|Nitrospirae	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR34280931_k127_555132_7	330214.NIDE1759	3.99e-311	959.0	COG0778@1|root,COG0778@2|Bacteria,3J0XZ@40117|Nitrospirae	40117|Nitrospirae	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_81	330214.NIDE1761	8.023e-66	229.0	2C8BN@1|root,32RKS@2|Bacteria	2|Bacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
SRR34280931_k127_555132_88	330214.NIDE1762	5.809e-60	213.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ,Wzy_C
SRR34280931_k127_555132_80	330214.NIDE1763	1.881e-66	240.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HisKA,LpxC,PAS_3,Response_reg
SRR34280931_k127_555132_3	330214.NIDE1765	0.0	1720.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR34280931_k127_555132_33	330214.NIDE1766	2.989e-175	559.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23,HlyD_D4
SRR34280931_k127_555132_21	330214.NIDE1767	1.03e-217	682.0	COG1538@1|root,COG1538@2|Bacteria,3J1F2@40117|Nitrospirae	40117|Nitrospirae	MU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR34280931_k127_555132_121	762376.AXYL_03776	3.817e-13	71.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,3T47H@506|Alcaligenaceae	28216|Betaproteobacteria	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR34280931_k127_555132_125	1266908.AQPB01000042_gene1093	9.275e-10	64.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1SIVH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_2,rve_3
SRR34280931_k127_555132_47	710685.MycrhN_2475	6.282e-132	427.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria,23EYZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	4.1.1.45,4.1.1.46,4.1.1.52	ko:K03392,ko:K14333,ko:K22213	ko00362,ko00380,ko00627,ko01100,ko01120,map00362,map00380,map00627,map01100,map01120	M00038	R00821,R04323	RC00390,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR34280931_k127_555132_118	330214.NIDE2608	3.519e-14	74.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Y1_Tnp
SRR34280931_k127_555132_143	2903.EOD25970	0.0006783	51.0	COG0457@1|root,KOG1124@2759|Eukaryota	2759|Eukaryota	O	cellular component assembly	TTC6	-	-	ko:K12869	ko03040,map03040	M00355	-	-	ko00000,ko00001,ko00002,ko03036,ko03041	-	-	-	TPR_1,TPR_11,TPR_14,TPR_16,TPR_19,TPR_8
SRR34280931_k127_555132_9	330214.NIDE1769	8.428e-291	900.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05577	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR34280931_k127_555132_2	330214.NIDE1770	0.0	1750.0	COG3002@1|root,COG3002@2|Bacteria,3J0VY@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
SRR34280931_k127_555132_86	330214.NIDE1771	4.444e-63	218.0	COG0347@1|root,COG0347@2|Bacteria,3J17N@40117|Nitrospirae	2|Bacteria	K	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	DUF190,P-II
SRR34280931_k127_555132_4	330214.NIDE1772	0.0	1144.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,3J0YT@40117|Nitrospirae	40117|Nitrospirae	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9
SRR34280931_k127_555132_11	330214.NIDE1773	1.036e-256	796.0	COG2204@1|root,COG2204@2|Bacteria,3J0YM@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_555132_49	1283300.ATXB01000001_gene1693	2.145e-131	432.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XGA0@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR34280931_k127_555132_8	316067.Geob_1217	8.374e-303	957.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM Malto-oligosyltrehalose synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR34280931_k127_555132_104	76114.ebB239	9.105e-39	149.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2VT3J@28216|Betaproteobacteria,2KX1U@206389|Rhodocyclales	206389|Rhodocyclales	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR34280931_k127_555132_45	330214.NIDE3195	4.546e-139	451.0	COG0438@1|root,COG0438@2|Bacteria,3J120@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_555132_15	886293.Sinac_0738	1.258e-245	771.0	COG3387@1|root,COG3387@2|Bacteria,2IXUW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR34280931_k127_555132_116	1112217.PPL19_06235	1.571e-18	95.0	2C82I@1|root,32K1E@2|Bacteria,1RE9K@1224|Proteobacteria,1SY9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_57	338963.Pcar_1976	2.229e-110	372.0	2CGDQ@1|root,32VRQ@2|Bacteria,1N5Z3@1224|Proteobacteria,43057@68525|delta/epsilon subdivisions,2WVDK@28221|Deltaproteobacteria,43V2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_91	330214.NIDE1164	4.509e-58	212.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_555132_95	330214.NIDE3247	1.588e-51	190.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_555132_89	378806.STAUR_6602	2.063e-59	214.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR34280931_k127_555132_76	402626.Rpic_0139	1.488e-71	245.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,2VQHR@28216|Betaproteobacteria,1K074@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ferritin, Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR34280931_k127_555132_128	1128421.JAGA01000001_gene2004	1.682e-08	57.0	COG1523@1|root,COG1523@2|Bacteria,2NPQU@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR34280931_k127_555132_115	93220.LV28_20185	2.697e-19	92.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,1K9H1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR34280931_k127_555132_138	497321.C664_14159	5.842e-05	50.0	COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2VWE0@28216|Betaproteobacteria,2KX5T@206389|Rhodocyclales	206389|Rhodocyclales	S	Propeptide PepSY amd peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRR34280931_k127_555132_119	754477.Q7C_2042	4.047e-14	73.0	COG5487@1|root,COG5487@2|Bacteria,1NCF3@1224|Proteobacteria,1SCWG@1236|Gammaproteobacteria,461H8@72273|Thiotrichales	72273|Thiotrichales	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
SRR34280931_k127_555132_112	595460.RRSWK_03372	2.851e-24	121.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR34280931_k127_555132_64	221288.JH992901_gene1951	5.805e-95	347.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
SRR34280931_k127_555132_71	1380391.JIAS01000011_gene5068	9.214e-82	297.0	COG2202@1|root,COG2203@1|root,COG2461@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2461@2|Bacteria,COG3920@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,HWE_HK,HisKA_2,PAS,PAS_3,PAS_4,PAS_9
SRR34280931_k127_555132_114	1408303.JNJJ01000078_gene1171	2.023e-19	93.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,4HIWV@91061|Bacilli,1ZIM7@1386|Bacillus	91061|Bacilli	C	COG1145 Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR34280931_k127_555132_22	472759.Nhal_1635	6.448e-204	659.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales	135613|Chromatiales	I	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
SRR34280931_k127_555132_90	757424.Hsero_2477	8.44e-59	212.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR34280931_k127_555132_53	1232410.KI421418_gene2231	4.799e-123	414.0	COG2982@1|root,COG2982@2|Bacteria,1PJZH@1224|Proteobacteria,42XG1@68525|delta/epsilon subdivisions,2WTDH@28221|Deltaproteobacteria,43T1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
SRR34280931_k127_555132_123	675815.VOA_000973	6.426e-12	76.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1S562@1236|Gammaproteobacteria,1XWDK@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_27	525897.Dbac_1184	4.216e-192	616.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR34280931_k127_555132_136	882378.RBRH_01938	1.043e-05	49.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2VJE3@28216|Betaproteobacteria,1K1AW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR34280931_k127_555132_19	1089551.KE386572_gene24	5.85e-224	716.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2U3EK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Domain of unknown function (DUF3459)	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR34280931_k127_555132_20	1123242.JH636435_gene892	8.276e-218	697.0	COG3408@1|root,COG3408@2|Bacteria,2IYTX@203682|Planctomycetes	203682|Planctomycetes	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR34280931_k127_555132_10	204669.Acid345_2151	4.542e-260	812.0	COG0028@1|root,COG0028@2|Bacteria,3Y3QI@57723|Acidobacteria,2JITT@204432|Acidobacteriia	204432|Acidobacteriia	EH	Belongs to the TPP enzyme family	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR34280931_k127_555132_70	105559.Nwat_1046	8.752e-86	299.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	tqsA	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
SRR34280931_k127_555132_85	1144275.COCOR_06481	1.835e-63	231.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,42ZG2@68525|delta/epsilon subdivisions,2WUWU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR34280931_k127_555132_127	502025.Hoch_5356	1.469e-08	62.0	29WSU@1|root,30IE6@2|Bacteria,1QDA3@1224|Proteobacteria,43276@68525|delta/epsilon subdivisions,2WXTW@28221|Deltaproteobacteria,2Z16N@29|Myxococcales	28221|Deltaproteobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR34280931_k127_555132_117	1123376.AUIU01000016_gene234	8.223e-18	86.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR34280931_k127_555132_130	338966.Ppro_0392	3.711e-07	57.0	COG4980@1|root,COG4980@2|Bacteria,1NB49@1224|Proteobacteria,42W0M@68525|delta/epsilon subdivisions,2WRVH@28221|Deltaproteobacteria,43SQE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR34280931_k127_555132_13	330214.NIDE1790	3.331e-251	787.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
SRR34280931_k127_555132_28	330214.NIDE1793	1.028e-189	595.0	COG4571@1|root,COG4571@2|Bacteria	2|Bacteria	M	Outer membrane protease	ompT	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009279,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0043170,GO:0044238,GO:0044425,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.23.48,3.4.23.49	ko:K01355,ko:K08477,ko:K08566,ko:K13520	ko01503,ko02020,map01503,map02020	M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Omptin
SRR34280931_k127_555132_23	330214.NIDE1794	6.087e-200	627.0	COG4581@1|root,COG4581@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR34280931_k127_555132_5	330214.NIDE1795	0.0	1120.0	COG4581@1|root,COG4581@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR34280931_k127_555132_12	330214.NIDE1796	1.783e-252	783.0	COG0448@1|root,COG0448@2|Bacteria,3J0BI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR34280931_k127_555132_30	330214.NIDE1798	5.625e-181	572.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR34280931_k127_555132_41	330214.NIDE1799	1.74e-150	479.0	COG1176@1|root,COG1176@2|Bacteria	2|Bacteria	P	putrescine transport	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR34280931_k127_555132_51	330214.NIDE1800	2.913e-130	421.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR34280931_k127_555132_25	330214.NIDE1801	7.398e-199	622.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iSB619.SA_RS05395	BPD_transp_1,SBP_bac_6,SBP_bac_8
SRR34280931_k127_555132_16	330214.NIDE1802	4.236e-243	757.0	COG1538@1|root,COG1538@2|Bacteria,3J1F2@40117|Nitrospirae	40117|Nitrospirae	MU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR34280931_k127_555132_24	330214.NIDE1803	3.351e-199	627.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR34280931_k127_555132_1	330214.NIDE1804	0.0	1880.0	COG3696@1|root,COG3696@2|Bacteria,3J0ZR@40117|Nitrospirae	40117|Nitrospirae	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR34280931_k127_555132_46	330214.NIDE1805	2.659e-135	436.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
SRR34280931_k127_555132_60	330214.NIDE1806	3.07e-106	345.0	COG0242@1|root,COG0242@2|Bacteria,3J146@40117|Nitrospirae	40117|Nitrospirae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR34280931_k127_555132_6	330214.NIDE1807	0.0	1041.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_555132_61	330214.NIDE1815	5.804e-105	343.0	COG1310@1|root,COG1310@2|Bacteria,3J0U8@40117|Nitrospirae	40117|Nitrospirae	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR34280931_k127_555132_35	330214.NIDE1816	2.641e-167	527.0	COG0476@1|root,COG0476@2|Bacteria,3J0X5@40117|Nitrospirae	40117|Nitrospirae	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR34280931_k127_555132_100	330214.NIDE1817	2.069e-44	164.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
SRR34280931_k127_555132_96	330214.NIDE1818	2.957e-51	181.0	COG1977@1|root,COG1977@2|Bacteria,3J0T2@40117|Nitrospirae	40117|Nitrospirae	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_555132_58	330214.NIDE1819	8.81e-110	355.0	COG0498@1|root,COG0498@2|Bacteria,3J0FZ@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_555132_40	330214.NIDE1819	5.247e-153	484.0	COG0498@1|root,COG0498@2|Bacteria,3J0FZ@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_555132_32	330214.NIDE1820	9.128e-176	552.0	COG0476@1|root,COG0476@2|Bacteria,3J0WD@40117|Nitrospirae	40117|Nitrospirae	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR34280931_k127_555132_26	330214.NIDE1821	6.347e-193	604.0	COG0031@1|root,COG0031@2|Bacteria,3J0HD@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_555132_108	330214.NIDE1822	1.56e-34	133.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_555132_69	330214.NIDE1825	3.692e-88	294.0	COG1502@1|root,COG1502@2|Bacteria,3J1DV@40117|Nitrospirae	40117|Nitrospirae	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR34280931_k127_555132_14	330214.NIDE1826	2.155e-249	773.0	COG0654@1|root,COG0654@2|Bacteria,3J16C@40117|Nitrospirae	40117|Nitrospirae	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR34280931_k127_555132_44	330214.NIDE1827	4.644e-145	462.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	ant1	-	2.7.7.47	ko:K00984,ko:K19279	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2,UPF0158
SRR34280931_k127_555132_48	330214.NIDE1828	8.586e-132	423.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR34280931_k127_555132_120	118166.JH976538_gene5265	4.329e-14	74.0	2EPMS@1|root,33H8E@2|Bacteria,1GAZH@1117|Cyanobacteria,1HGYT@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_78	330214.NIDE1836	2.939e-69	237.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
SRR34280931_k127_555132_77	330214.NIDE1837	1.055e-69	237.0	28YNP@1|root,2ZKGB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_38	330214.NIDE1838	3.748e-155	494.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_555132_74	330214.NIDE1839	7.815e-77	259.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR34280931_k127_555132_67	330214.NIDE1844	7.981e-90	299.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K11932	-	-	-	-	ko00000	-	-	-	Usp
SRR34280931_k127_555132_84	330214.NIDE1847	6.932e-64	222.0	2DQ7E@1|root,3353C@2|Bacteria,3J1EM@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRR34280931_k127_555132_50	330214.NIDE1848	2.466e-130	418.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	DUF3386,Kelch_1,Kelch_4,Kelch_5,fn3
SRR34280931_k127_555132_94	330214.NIDE1850	1.29e-51	187.0	COG2127@1|root,COG2127@2|Bacteria	2|Bacteria	T	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR34280931_k127_555132_29	330214.NIDE1853	9.311e-182	578.0	COG0635@1|root,COG0635@2|Bacteria,3J10W@40117|Nitrospirae	40117|Nitrospirae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR34280931_k127_555132_103	330214.NIDE1855	1.843e-39	147.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR34280931_k127_555132_56	330214.NIDE1858	2.832e-111	362.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE1858|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_82	330214.NIDE1859	8.945e-65	232.0	COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07676,ko:K10715,ko:K20976	ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026	M00474,M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg
SRR34280931_k127_555132_37	330214.NIDE1860	3.746e-156	496.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_555132_43	330214.NIDE1861	2.454e-145	463.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR34280931_k127_555132_93	330214.NIDE1862	5.5e-54	192.0	2CC8H@1|root,330SM@2|Bacteria,3J1D6@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_42	330214.NIDE1867	3.844e-146	465.0	2FKUS@1|root,34CF5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_555132_0	330214.NIDE1868	0.0	2301.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR34280931_k127_555132_18	330214.NIDE1870	1.01e-239	748.0	COG3437@1|root,COG3437@2|Bacteria,3J0ID@40117|Nitrospirae	2|Bacteria	T	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Protoglobin,Response_reg
SRR34280931_k127_555132_39	330214.NIDE1871	2.891e-153	485.0	COG0689@1|root,COG0689@2|Bacteria,3J0B8@40117|Nitrospirae	40117|Nitrospirae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR34280931_k127_555132_59	330214.NIDE1872	2.57e-108	354.0	COG0127@1|root,COG0127@2|Bacteria,3J0ST@40117|Nitrospirae	40117|Nitrospirae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR34280931_k127_555132_17	330214.NIDE0186	1.279e-240	750.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR34280931_k127_555132_72	234267.Acid_5388	1.205e-80	277.0	COG3409@1|root,COG3409@2|Bacteria,3Y7KF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
SRR34280931_k127_56384_2	330214.NIDE2986	5.627e-42	153.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRR34280931_k127_56384_1	330214.NIDE2985	7.026e-83	278.0	COG1778@1|root,COG1778@2|Bacteria,3J1EJ@40117|Nitrospirae	40117|Nitrospirae	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
SRR34280931_k127_56384_0	330214.NIDE2984	1.737e-287	887.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,3J0FF@40117|Nitrospirae	40117|Nitrospirae	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR34280931_k127_56384_3	330214.NIDE2983	1.26e-26	109.0	COG1109@1|root,COG1109@2|Bacteria,3J0AF@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR34280931_k127_582464_4	330214.NIDE3933	2.944e-139	445.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K01420,ko:K10914,ko:K21556,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
SRR34280931_k127_582464_1	330214.NIDE3934	4.008e-210	656.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_582464_3	330214.NIDE3935	9.448e-195	608.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_582464_2	330214.NIDE3936	6.748e-199	622.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_582464_0	330214.NIDE3937	3.734e-241	745.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR34280931_k127_59303_40	330214.NIDE3937	5.107e-12	66.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR34280931_k127_59303_9	330214.NIDE3939	1.231e-255	794.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PilZ,Sigma54_activat
SRR34280931_k127_59303_36	330214.NIDE3940	2.354e-68	234.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE3940|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_59303_0	330214.NIDE3941	0.0	1280.0	COG2202@1|root,COG3290@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,3J124@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR34280931_k127_59303_6	330214.NIDE3942	2.745e-285	879.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_59303_13	330214.NIDE3943	7.482e-227	709.0	COG0845@1|root,COG0845@2|Bacteria,3J0HQ@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR34280931_k127_59303_11	330214.NIDE3944	8.298e-234	728.0	COG0577@1|root,COG0577@2|Bacteria,3J0EW@40117|Nitrospirae	40117|Nitrospirae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_59303_16	330214.NIDE3945	1.301e-213	669.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	nhaP	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR34280931_k127_59303_8	330214.NIDE3947	1.824e-262	823.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscM	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR34280931_k127_59303_18	330214.NIDE3948	8.364e-210	658.0	2CB8G@1|root,2Z88H@2|Bacteria	2|Bacteria	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRR34280931_k127_59303_23	330214.NIDE3950	2.408e-178	562.0	COG0320@1|root,COG0320@2|Bacteria,3J0IY@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR34280931_k127_59303_15	330214.NIDE3951	6.777e-222	692.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR34280931_k127_59303_20	330214.NIDE3952	7.174e-200	623.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Biotin_lipoyl,Transket_pyr,Transketolase_C
SRR34280931_k127_59303_22	330214.NIDE3953	1.498e-187	588.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR34280931_k127_59303_33	330214.NIDE3956	8.854e-107	348.0	COG0424@1|root,COG0424@2|Bacteria	2|Bacteria	D	maF-like protein	maf	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944	2.1.1.190	ko:K03215,ko:K06287	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Maf
SRR34280931_k127_59303_10	330214.NIDE3957	2.006e-238	740.0	COG0042@1|root,COG0042@2|Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR34280931_k127_59303_12	330214.NIDE3958	6.96e-231	723.0	COG3220@1|root,COG3220@2|Bacteria,3J130@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
SRR34280931_k127_59303_25	330214.NIDE3959	2.75e-143	456.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	1.1.1.42,1.3.1.85	ko:K00031,ko:K14446	ko00020,ko00480,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00373,M00740	R00267,R00268,R01899,R09291	RC00001,RC00084,RC00114,RC00626,RC02481,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,GGDEF,PAS_9
SRR34280931_k127_59303_17	330214.NIDE3960	3.095e-213	664.0	COG1611@1|root,COG1611@2|Bacteria,3J169@40117|Nitrospirae	40117|Nitrospirae	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR34280931_k127_59303_24	330214.NIDE3961	3.262e-164	518.0	COG2404@1|root,COG2404@2|Bacteria,3J12M@40117|Nitrospirae	40117|Nitrospirae	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_59303_29	330214.NIDE3962	2.347e-131	424.0	COG0705@1|root,COG0705@2|Bacteria,3J16E@40117|Nitrospirae	40117|Nitrospirae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR34280931_k127_59303_2	330214.NIDE3963	0.0	1011.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR34280931_k127_59303_19	330214.NIDE3964	1.14e-200	632.0	COG0026@1|root,COG0026@2|Bacteria,3J11N@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR34280931_k127_59303_34	330214.NIDE3965	1.62e-86	291.0	COG0041@1|root,COG0041@2|Bacteria,3J0P8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR34280931_k127_59303_4	330214.NIDE3966	2.473e-308	951.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cvaA	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
SRR34280931_k127_59303_5	330214.NIDE3967	1.886e-287	886.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR34280931_k127_59303_1	330214.NIDE3968	0.0	1063.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_59303_3	330214.NIDE3969	4.256e-318	979.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_59303_28	330214.NIDE3970	5.81e-132	424.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	VVA0018	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR34280931_k127_59303_27	330214.NIDE3971	2.825e-132	425.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR34280931_k127_59303_21	330214.NIDE3972	9.735e-192	604.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR34280931_k127_59303_31	330214.NIDE3973	1.52e-121	391.0	COG1945@1|root,COG1945@2|Bacteria	2|Bacteria	I	arginine decarboxylase activity	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
SRR34280931_k127_59303_7	330214.NIDE3974	7.071e-269	832.0	COG1012@1|root,COG1012@2|Bacteria,3J0YN@40117|Nitrospirae	40117|Nitrospirae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR34280931_k127_59303_30	330214.NIDE3976	6.072e-122	394.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR34280931_k127_59303_14	330214.NIDE3977	1.923e-226	707.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR34280931_k127_59303_26	330214.NIDE3978	5.154e-137	438.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	ArsP_1,Zip
SRR34280931_k127_59303_37	330214.NIDE1561	6.409e-56	203.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
SRR34280931_k127_59303_35	330214.NIDE3985	7.317e-72	251.0	2DMP9@1|root,32SV1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
SRR34280931_k127_59303_43	330214.NIDE4010	0.000392	44.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
SRR34280931_k127_59303_42	888060.HMPREF9081_2483	5.305e-06	53.0	COG1396@1|root,COG1396@2|Bacteria,1VFUQ@1239|Firmicutes,4H9GM@909932|Negativicutes	909932|Negativicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR34280931_k127_59303_41	1121289.JHVL01000007_gene2744	2.863e-11	68.0	COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,24KV8@186801|Clostridia,36JDU@31979|Clostridiaceae	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
SRR34280931_k127_631351_1	330214.NIDE2866	1.412e-138	443.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR34280931_k127_631351_0	330214.NIDE2865	6.328e-178	567.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp
SRR34280931_k127_631351_2	330214.NIDE2864	2.482e-62	216.0	COG1215@1|root,COG1215@2|Bacteria,3J15U@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_649542_14	330214.NIDE1165	1.748e-60	211.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR34280931_k127_649542_0	330214.NIDE1167	0.0	2434.0	COG1201@1|root,COG1201@2|Bacteria	2|Bacteria	L	RNA secondary structure unwinding	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR34280931_k127_649542_6	330214.NIDE1168	3.809e-152	484.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR34280931_k127_649542_2	330214.NIDE1172	0.0	1250.0	COG1805@1|root,COG4402@1|root,COG1805@2|Bacteria,COG4402@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2330,NQR2_RnfD_RnfE
SRR34280931_k127_649542_16	153948.NAL212_1039	2.04e-33	139.0	2BP06@1|root,32HQG@2|Bacteria,1RK5Z@1224|Proteobacteria,2WBIA@28216|Betaproteobacteria,3736M@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_649542_7	330214.NIDE1182	3.692e-128	423.0	2E7Z1@1|root,332DD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_649542_11	330214.NIDE1183	1.963e-83	282.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_649542_4	330214.NIDE1184	1.869e-196	615.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR34280931_k127_649542_1	330214.NIDE1185	0.0	2044.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3J17I@40117|Nitrospirae	40117|Nitrospirae	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20,6.2.1.3	ko:K01897,ko:K05939	ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R01406,R04864	RC00004,RC00014,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,Acyltransferase
SRR34280931_k127_649542_3	330214.NIDE1186	2.928e-317	981.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS1	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
SRR34280931_k127_649542_5	330214.NIDE1187	1.653e-154	492.0	COG2264@1|root,COG2264@2|Bacteria,3J1B7@40117|Nitrospirae	40117|Nitrospirae	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR34280931_k127_649542_12	330214.NIDE1188	1.277e-76	260.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR34280931_k127_649542_9	330214.NIDE1189	1.241e-125	403.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR34280931_k127_649542_10	330214.NIDE1190	2.012e-123	403.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR34280931_k127_649542_8	330214.NIDE1191	1.206e-127	414.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
SRR34280931_k127_66535_5	84531.JMTZ01000038_gene3636	3.127e-14	76.0	28NRK@1|root,332DP@2|Bacteria,1R3A3@1224|Proteobacteria,1T65F@1236|Gammaproteobacteria,1X9W9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_66535_0	261292.Nit79A3_1011	1.575e-120	391.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VR69@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Rhs Element Vgr Protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR34280931_k127_66535_1	1144275.COCOR_02859	1.883e-118	392.0	COG3500@1|root,COG3500@2|Bacteria,1R67C@1224|Proteobacteria,4387V@68525|delta/epsilon subdivisions,2X3HN@28221|Deltaproteobacteria,2YW57@29|Myxococcales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR34280931_k127_66535_2	261292.Nit79A3_1008	2.127e-68	240.0	COG1652@1|root,COG1652@2|Bacteria,1NC3Q@1224|Proteobacteria,2VW0G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_66535_4	261292.Nit79A3_1007	4.895e-56	199.0	2DMAD@1|root,32C5Y@2|Bacteria,1RKVJ@1224|Proteobacteria,2VS9H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR34280931_k127_66535_3	261292.Nit79A3_1006	2.544e-58	208.0	COG3497@1|root,COG3497@2|Bacteria,1NSAQ@1224|Proteobacteria	1224|Proteobacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1C
SRR34280931_k127_672694_33	330214.NIDE3236	7.449e-21	91.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
SRR34280931_k127_672694_18	330214.NIDE3235	8.47e-91	303.0	COG5278@1|root,COG5278@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE3
SRR34280931_k127_672694_25	330214.NIDE3233	8.089e-50	179.0	COG3189@1|root,COG3189@2|Bacteria,3J1F0@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR34280931_k127_672694_36	330214.NIDE3231	1.418e-05	50.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
SRR34280931_k127_672694_34	330214.NIDE3231	2.053e-14	74.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
SRR34280931_k127_672694_32	1392488.JHZY01000002_gene928	7.485e-25	116.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1HXP9@117743|Flavobacteriia,2XI48@283735|Leeuwenhoekiella	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR34280931_k127_672694_27	330214.NIDE3228	1.029e-44	167.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE3228|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_672694_38	330214.NIDE0876	3.383e-05	49.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K10936,ko:K16079	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.4.2.1	-	-	OMP_b-brl
SRR34280931_k127_672694_2	330214.NIDE3226	0.0	1117.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR34280931_k127_672694_23	330214.NIDE3224	3.003e-58	205.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
SRR34280931_k127_672694_11	330214.NIDE3222	3.151e-179	564.0	COG0123@1|root,COG0123@2|Bacteria,3J0P2@40117|Nitrospirae	40117|Nitrospirae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR34280931_k127_672694_4	330214.NIDE3221	4.612e-271	836.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_672694_9	330214.NIDE3220	3.79e-188	591.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	rhdA	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR34280931_k127_672694_22	330214.NIDE3219	1.308e-60	211.0	2DQ5D@1|root,334TW@2|Bacteria	2|Bacteria	S	Small metal-binding protein	smbP	-	-	-	-	-	-	-	-	-	-	-	SMBP
SRR34280931_k127_672694_12	330214.NIDE3218	3.073e-142	457.0	COG0388@1|root,COG0388@2|Bacteria,3J11H@40117|Nitrospirae	40117|Nitrospirae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR34280931_k127_672694_15	330214.NIDE3217	1.969e-113	366.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR34280931_k127_672694_0	330214.NIDE3216	0.0	1735.0	COG0178@1|root,COG0178@2|Bacteria,3J0ZV@40117|Nitrospirae	40117|Nitrospirae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
SRR34280931_k127_672694_16	330214.NIDE3215	1.219e-110	362.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	nat	-	2.3.1.118,2.3.1.5	ko:K00622,ko:K00675	ko00232,ko00633,ko00983,ko01100,ko01110,ko01120,ko05204,map00232,map00633,map00983,map01100,map01110,map01120,map05204	-	R07940,R08036,R08248,R08250,R11902	RC00004,RC00416,RC00962,RC02961	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_2
SRR34280931_k127_672694_29	504728.K649_04110	1.103e-40	154.0	COG2445@1|root,COG2445@2|Bacteria,1WK62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR34280931_k127_672694_26	330214.NIDE0028	1.33e-46	172.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR34280931_k127_672694_37	875328.JDM601_2059	3.261e-05	50.0	COG2161@1|root,COG2161@2|Bacteria,2GUI1@201174|Actinobacteria,23AW9@1762|Mycobacteriaceae	201174|Actinobacteria	K	Antitoxin component of a toxin-antitoxin (TA) module	relF	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR34280931_k127_672694_20	330214.NIDE3201	1.09e-65	224.0	2C4PS@1|root,2ZHNK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_672694_10	330214.NIDE3200	3.626e-182	582.0	COG1234@1|root,COG1234@2|Bacteria,3J113@40117|Nitrospirae	40117|Nitrospirae	S	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	-
SRR34280931_k127_672694_3	330214.NIDE3198	3.494e-302	933.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR34280931_k127_672694_7	330214.NIDE3195	1.727e-231	717.0	COG0438@1|root,COG0438@2|Bacteria,3J120@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_672694_6	330214.NIDE3194	9.27e-247	765.0	COG0477@1|root,COG2814@2|Bacteria,3J0RT@40117|Nitrospirae	40117|Nitrospirae	EGP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR34280931_k127_672694_13	330214.NIDE3193	6.625e-130	424.0	COG2823@1|root,COG3170@1|root,COG2823@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	tolA	-	2.7.13.3	ko:K03407,ko:K03646,ko:K04065,ko:K06596,ko:K07277,ko:K12065,ko:K13593	ko02020,ko02025,ko02030,ko04112,map02020,map02025,map02030,map04112	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko02044,ko03029	1.B.33,2.C.1.2,3.A.7.11.1	-	-	BON,TrbI
SRR34280931_k127_672694_5	330214.NIDE3192	6.427e-255	790.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR34280931_k127_672694_1	330214.NIDE3191	0.0	1394.0	COG3408@1|root,COG3408@2|Bacteria,3J0Z8@40117|Nitrospirae	40117|Nitrospirae	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR34280931_k127_672694_8	330214.NIDE3190	5.721e-218	689.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR34280931_k127_681542_20	330214.NIDE0337	8.105e-176	553.0	COG2946@1|root,COG2946@2|Bacteria	2|Bacteria	L	Replication initiation factor	nicK	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
SRR34280931_k127_681542_36	330214.NIDE0285	4.431e-73	250.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
SRR34280931_k127_681542_49	330214.NIDE0294	3.827e-09	60.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
SRR34280931_k127_681542_31	661478.OP10G_2990	6.407e-85	311.0	COG0642@1|root,COG2205@2|Bacteria	661478.OP10G_2990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681542_16	330214.NIDE0282	2.665e-209	654.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE0282|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681542_37	330214.NIDE0281	3.579e-72	245.0	COG1734@1|root,COG1734@2|Bacteria,3J0TH@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR34280931_k127_681542_25	330214.NIDE0280	1.08e-122	394.0	COG0353@1|root,COG0353@2|Bacteria,3J0KB@40117|Nitrospirae	40117|Nitrospirae	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR34280931_k127_681542_46	330214.NIDE0279	1.477e-57	202.0	COG0718@1|root,COG0718@2|Bacteria,3J1EY@40117|Nitrospirae	40117|Nitrospirae	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR34280931_k127_681542_2	330214.NIDE0278	5.78e-308	952.0	COG2812@1|root,COG2812@2|Bacteria,3J0DD@40117|Nitrospirae	40117|Nitrospirae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR34280931_k127_681542_0	330214.NIDE0277	0.0	1181.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
SRR34280931_k127_681542_48	330214.NIDE0276	2.532e-23	103.0	COG3264@1|root,COG3264@2|Bacteria,3J0R7@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
SRR34280931_k127_681542_33	330214.NIDE0275	1e-81	276.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR34280931_k127_681542_8	330214.NIDE0274	3.205e-261	817.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
SRR34280931_k127_681542_32	330214.NIDE0273	2.027e-82	280.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	Ras
SRR34280931_k127_681542_4	330214.NIDE0271	1.941e-299	928.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PilZ,Sigma54_activat
SRR34280931_k127_681542_47	330214.NIDE0270	5.823e-29	118.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Phosphonate-bd
SRR34280931_k127_681542_12	330214.NIDE0268	1.261e-221	691.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SRR34280931_k127_681542_35	330214.NIDE0267	1.744e-77	264.0	COG1970@1|root,COG1970@2|Bacteria,3J19K@40117|Nitrospirae	40117|Nitrospirae	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR34280931_k127_681542_19	330214.NIDE0266	1.651e-178	569.0	COG1360@1|root,COG4942@1|root,COG1360@2|Bacteria,COG4942@2|Bacteria	2|Bacteria	D	peptidase	motB	-	-	ko:K02557,ko:K21471	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011,ko02000,ko02035	1.A.30.1	-	-	OmpA
SRR34280931_k127_681542_17	330214.NIDE0265	2.572e-199	633.0	COG1360@1|root,COG4372@1|root,COG1360@2|Bacteria,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	ebh	-	2.1.1.80,3.1.1.61	ko:K02557,ko:K07484,ko:K13924,ko:K21471	ko02020,ko02030,ko02040,map02020,map02030,map02040	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000,ko02022,ko02035	1.A.30.1	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,OmpA,zf-IS66
SRR34280931_k127_681542_15	330214.NIDE0264	1.021e-216	678.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR34280931_k127_681542_18	330214.NIDE0263	1.468e-187	590.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
SRR34280931_k127_681542_9	330214.NIDE0262	2.942e-248	771.0	COG0544@1|root,COG0544@2|Bacteria,3J12E@40117|Nitrospirae	40117|Nitrospirae	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
SRR34280931_k127_681542_22	330214.NIDE0261	1.391e-131	420.0	COG0740@1|root,COG0740@2|Bacteria,3J0A3@40117|Nitrospirae	40117|Nitrospirae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR34280931_k127_681542_7	330214.NIDE0260	4.534e-268	827.0	COG1219@1|root,COG1219@2|Bacteria,3J0AM@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR34280931_k127_681542_29	330214.NIDE0258	4.284e-95	318.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ,Response_reg
SRR34280931_k127_681542_30	330214.NIDE0257	4.982e-92	304.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ,Response_reg
SRR34280931_k127_681542_24	330214.NIDE0255	3.951e-129	418.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR34280931_k127_681542_11	330214.NIDE0254	1.073e-228	711.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR34280931_k127_681542_21	330214.NIDE0251	3.965e-140	449.0	COG2071@1|root,COG2071@2|Bacteria,3J0PV@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR34280931_k127_681542_5	330214.NIDE0250	5.567e-298	917.0	COG0531@1|root,COG0531@2|Bacteria,3J0ZY@40117|Nitrospirae	40117|Nitrospirae	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR34280931_k127_681542_39	330214.NIDE0248	4.238e-68	237.0	2EC6I@1|root,33651@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
SRR34280931_k127_681542_13	330214.NIDE0246	1.412e-220	687.0	COG1472@1|root,COG1472@2|Bacteria,3J0MK@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR34280931_k127_681542_3	330214.NIDE0245	1.38e-299	926.0	COG0260@1|root,COG0260@2|Bacteria,3J0X7@40117|Nitrospirae	40117|Nitrospirae	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR34280931_k127_681542_26	330214.NIDE0244	1.249e-119	389.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR34280931_k127_681542_23	330214.NIDE0243	4.415e-131	423.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
SRR34280931_k127_681542_14	330214.NIDE0241	4.568e-219	691.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR34280931_k127_681542_38	330214.NIDE0240	1.99e-68	233.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE0240|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681542_1	330214.NIDE0238	8.063e-317	993.0	COG1198@1|root,COG1198@2|Bacteria,3J0MZ@40117|Nitrospirae	40117|Nitrospirae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR34280931_k127_681542_10	330214.NIDE0237	9.658e-230	724.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SRR34280931_k127_681542_27	330214.NIDE0235	2.121e-111	361.0	COG0377@1|root,COG0377@2|Bacteria,3J11S@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR34280931_k127_681542_28	330214.NIDE0234	5.604e-102	332.0	COG0852@1|root,COG0852@2|Bacteria,3J168@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR34280931_k127_681542_6	330214.NIDE0233	1.533e-280	861.0	COG0649@1|root,COG0649@2|Bacteria,3J0FM@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
SRR34280931_k127_681542_45	330214.NIDE0232	6.075e-59	204.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	2|Bacteria	C	Molydopterin dinucleotide binding domain	hcnA	-	1.4.99.5,1.5.3.1	ko:K00302,ko:K10814	ko00260,ko00460,ko01100,ko01110,map00260,map00460,map01100,map01110	-	R00374,R00610,R05704	RC00060,RC00557,RC02808	ko00000,ko00001,ko01000,ko02042	-	-	-	Fer2_4
SRR34280931_k127_681572_127	330214.NIDE1319	6.287e-23	98.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR34280931_k127_681572_107	330214.NIDE1320	1.986e-50	181.0	COG0186@1|root,COG0186@2|Bacteria,3J0TQ@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR34280931_k127_681572_90	330214.NIDE1321	1.558e-74	250.0	COG0093@1|root,COG0093@2|Bacteria,3J0JD@40117|Nitrospirae	40117|Nitrospirae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR34280931_k127_681572_102	330214.NIDE1322	3.351e-57	201.0	COG0198@1|root,COG0198@2|Bacteria,3J0VK@40117|Nitrospirae	40117|Nitrospirae	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR34280931_k127_681572_59	330214.NIDE1323	3.532e-117	379.0	COG0094@1|root,COG0094@2|Bacteria,3J0HN@40117|Nitrospirae	40117|Nitrospirae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR34280931_k127_681572_121	330214.NIDE1324	4.652e-32	125.0	COG0199@1|root,COG0199@2|Bacteria,3J1C2@40117|Nitrospirae	40117|Nitrospirae	J	30S ribosomal protein S14	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR34280931_k127_681572_88	330214.NIDE1325	1.258e-75	255.0	COG0096@1|root,COG0096@2|Bacteria,3J0SJ@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR34280931_k127_681572_70	330214.NIDE1326	3.839e-102	333.0	COG0097@1|root,COG0097@2|Bacteria,3J0JB@40117|Nitrospirae	40117|Nitrospirae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR34280931_k127_681572_99	330214.NIDE1327	1.832e-63	218.0	COG0256@1|root,COG0256@2|Bacteria,3J0QF@40117|Nitrospirae	40117|Nitrospirae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR34280931_k127_681572_76	330214.NIDE1328	1.241e-94	311.0	COG0098@1|root,COG0098@2|Bacteria,3J0M3@40117|Nitrospirae	40117|Nitrospirae	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR34280931_k127_681572_134	1123354.AUDR01000018_gene1234	1.417e-07	61.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,1KRUI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein L30p/L7e	-	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR34280931_k127_681572_108	1347392.CCEZ01000013_gene2671	3.762e-49	181.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,36I11@31979|Clostridiaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR34280931_k127_681572_20	330214.NIDE1331	2.411e-277	855.0	COG0201@1|root,COG0201@2|Bacteria,3J0C0@40117|Nitrospirae	40117|Nitrospirae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR34280931_k127_681572_63	330214.NIDE1332	5.155e-113	367.0	COG0563@1|root,COG0563@2|Bacteria,3J0K3@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR34280931_k127_681572_46	330214.NIDE1333	1.415e-152	483.0	COG0024@1|root,COG0024@2|Bacteria,3J0GR@40117|Nitrospirae	40117|Nitrospirae	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR34280931_k127_681572_116	330214.NIDE1334	7.817e-40	148.0	COG0361@1|root,COG0361@2|Bacteria,3J0QB@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR34280931_k127_681572_131	1280668.ATVT01000003_gene2508	2.367e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,4C0FI@830|Butyrivibrio	186801|Clostridia	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR34280931_k127_681572_93	330214.NIDE1336	2.166e-71	242.0	COG0099@1|root,COG0099@2|Bacteria,3J0Q5@40117|Nitrospirae	40117|Nitrospirae	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR34280931_k127_681572_91	330214.NIDE1337	9.805e-74	249.0	COG0100@1|root,COG0100@2|Bacteria,3J0KE@40117|Nitrospirae	40117|Nitrospirae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR34280931_k127_681572_56	330214.NIDE1338	4.61e-129	413.0	COG0522@1|root,COG0522@2|Bacteria,3J0IC@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR34280931_k127_681572_32	330214.NIDE1339	7.412e-207	645.0	COG0202@1|root,COG0202@2|Bacteria,3J0AR@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR34280931_k127_681572_94	330214.NIDE1340	3.888e-70	239.0	COG0203@1|root,COG0203@2|Bacteria,3J0TE@40117|Nitrospirae	40117|Nitrospirae	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR34280931_k127_681572_64	330214.NIDE1341	2.831e-110	357.0	COG5375@1|root,COG5375@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRR34280931_k127_681572_96	330214.NIDE1342	4.135e-69	242.0	COG1934@1|root,COG1934@2|Bacteria,3J1EG@40117|Nitrospirae	40117|Nitrospirae	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRR34280931_k127_681572_53	330214.NIDE1343	8.1e-142	452.0	COG1137@1|root,COG1137@2|Bacteria,3J0GJ@40117|Nitrospirae	40117|Nitrospirae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR34280931_k127_681572_14	330214.NIDE1344	3.47e-305	938.0	COG1508@1|root,COG1508@2|Bacteria,3J0AT@40117|Nitrospirae	40117|Nitrospirae	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR34280931_k127_681572_130	269799.Gmet_1284	3.819e-18	91.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR34280931_k127_681572_40	330214.NIDE1346	2.56e-173	545.0	COG1660@1|root,COG1660@2|Bacteria,3J0IK@40117|Nitrospirae	40117|Nitrospirae	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR34280931_k127_681572_115	330214.NIDE1347	1.453e-40	150.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	racA	-	-	ko:K11686,ko:K13640,ko:K18997	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	DUF1836,MerR_1,MerR_2
SRR34280931_k127_681572_30	330214.NIDE1348	3.946e-214	668.0	COG4972@1|root,COG4972@2|Bacteria,3J177@40117|Nitrospirae	40117|Nitrospirae	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR34280931_k127_681572_68	330214.NIDE1349	5.528e-104	340.0	COG3166@1|root,COG3166@2|Bacteria,3J1EX@40117|Nitrospirae	40117|Nitrospirae	NU	Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR34280931_k127_681572_62	330214.NIDE1350	3.401e-114	370.0	COG3167@1|root,COG3167@2|Bacteria,3J1BH@40117|Nitrospirae	40117|Nitrospirae	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR34280931_k127_681572_72	330214.NIDE1351	4.555e-99	328.0	COG3168@1|root,COG3168@2|Bacteria,3J1AT@40117|Nitrospirae	40117|Nitrospirae	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
SRR34280931_k127_681572_6	330214.NIDE1352	0.0	1116.0	COG4796@1|root,COG4796@2|Bacteria,3J0Q9@40117|Nitrospirae	40117|Nitrospirae	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin,Secretin_N
SRR34280931_k127_681572_36	330214.NIDE1353	1.716e-189	597.0	COG0337@1|root,COG0337@2|Bacteria,3J0GA@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR34280931_k127_681572_24	330214.NIDE1354	8.706e-249	772.0	COG2203@1|root,COG3605@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,3J0XQ@40117|Nitrospirae	40117|Nitrospirae	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR34280931_k127_681572_123	161156.JQKW01000011_gene1008	1.036e-29	134.0	COG3074@1|root,COG3074@2|Bacteria,2GI62@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_34	269798.CHU_1255	4.576e-197	623.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	urtA	-	-	ko:K01999,ko:K11959	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	iJN678.amiC	Peripla_BP_5
SRR34280931_k127_681572_67	1532557.JL37_12610	2.697e-105	361.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJ7X@28216|Betaproteobacteria,3T5N7@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
SRR34280931_k127_681572_61	1380394.JADL01000008_gene3693	1.304e-114	382.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TTN2@28211|Alphaproteobacteria,2JPNN@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
SRR34280931_k127_681572_77	868595.Desca_0741	2.445e-91	306.0	COG4674@1|root,COG4674@2|Bacteria,1UIU8@1239|Firmicutes,25ES1@186801|Clostridia,267F1@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
SRR34280931_k127_681572_92	118161.KB235922_gene3476	5.713e-73	252.0	COG0410@1|root,COG0410@2|Bacteria,1G0UF@1117|Cyanobacteria,3VHRA@52604|Pleurocapsales	1117|Cyanobacteria	E	TIGRFAM urea ABC transporter, ATP-binding protein UrtE	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
SRR34280931_k127_681572_112	1123507.ATVQ01000001_gene1863	2.028e-43	160.0	COG0831@1|root,COG0831@2|Bacteria,2IKNA@201174|Actinobacteria,1W9IP@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
SRR34280931_k127_681572_111	694430.Natoc_1483	4.428e-44	165.0	COG0832@1|root,arCOG04527@2157|Archaea,2XXYJ@28890|Euryarchaeota,23W9C@183963|Halobacteria	183963|Halobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
SRR34280931_k127_681572_17	1173025.GEI7407_2699	8.306e-286	887.0	COG0804@1|root,COG0804@2|Bacteria,1G12D@1117|Cyanobacteria,1H6ZH@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
SRR34280931_k127_681572_124	358396.C445_14077	3.517e-28	123.0	COG0830@1|root,arCOG04530@2157|Archaea,2XTEA@28890|Euryarchaeota,23UV1@183963|Halobacteria	183963|Halobacteria	O	Urease accessory protein UreF	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
SRR34280931_k127_681572_78	187272.Mlg_0187	1.73e-89	299.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,1WXS2@135613|Chromatiales	135613|Chromatiales	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
SRR34280931_k127_681572_122	1380346.JNIH01000042_gene5554	3.057e-31	134.0	COG0829@1|root,COG0829@2|Bacteria,2HHBD@201174|Actinobacteria	201174|Actinobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
SRR34280931_k127_681572_11	330214.NIDE1358	0.0	1002.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3J0EB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR34280931_k127_681572_37	330214.NIDE1359	5.042e-184	580.0	2DZT8@1|root,32VIB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_23	330214.NIDE1360	9.124e-255	789.0	COG0004@1|root,COG0004@2|Bacteria,3J0IS@40117|Nitrospirae	40117|Nitrospirae	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR34280931_k127_681572_100	330214.NIDE1361	2.477e-63	219.0	COG0347@1|root,COG0347@2|Bacteria,3J0P1@40117|Nitrospirae	40117|Nitrospirae	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR34280931_k127_681572_1	330214.NIDE1362	0.0	1605.0	COG2844@1|root,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.42,2.7.7.59,2.7.7.89	ko:K00982,ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR34280931_k127_681572_13	330214.NIDE1363	1.409e-317	972.0	COG0174@1|root,COG0174@2|Bacteria,3J0AS@40117|Nitrospirae	40117|Nitrospirae	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR34280931_k127_681572_43	330214.NIDE1364	4.676e-166	526.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	nirC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02598,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.3	-	iSF_1195.SF3386,iS_1188.S4377	Form_Nir_trans
SRR34280931_k127_681572_89	330214.NIDE1365	8.619e-75	257.0	COG1513@1|root,COG1513@2|Bacteria	2|Bacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
SRR34280931_k127_681572_8	330214.NIDE1367	0.0	1036.0	COG0155@1|root,COG0155@2|Bacteria,3J10S@40117|Nitrospirae	40117|Nitrospirae	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR34280931_k127_681572_47	330214.NIDE1368	2.472e-152	483.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	opuCA	-	2.7.7.7	ko:K02342,ko:K05847,ko:K07182	ko00230,ko00240,ko01100,ko02010,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02010,map03030,map03430,map03440	M00209,M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02000,ko03032,ko03400	3.A.1.12	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR34280931_k127_681572_31	330214.NIDE1370	3.795e-208	651.0	2CK9T@1|root,2Z7W9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_129	228410.NE2259	4.162e-22	96.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2VKUH@28216|Betaproteobacteria,3737I@32003|Nitrosomonadales	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR34280931_k127_681572_98	153948.NAL212_1184	4.083e-65	224.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2VKUH@28216|Betaproteobacteria,3737I@32003|Nitrosomonadales	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR34280931_k127_681572_133	658612.MD26_14670	3.624e-10	63.0	COG0693@1|root,COG0693@2|Bacteria,1NPQ7@1224|Proteobacteria,1S2MY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ThiJ PfpI domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR34280931_k127_681572_54	690850.Desaf_2571	4.692e-141	456.0	28ISW@1|root,2Z8RZ@2|Bacteria,1R4AR@1224|Proteobacteria,42Z0Y@68525|delta/epsilon subdivisions,2WTPF@28221|Deltaproteobacteria,2M7UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_50	237368.SCABRO_00363	1.64e-147	475.0	COG3177@1|root,COG3177@2|Bacteria,2J1MI@203682|Planctomycetes	203682|Planctomycetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
SRR34280931_k127_681572_3	330214.NIDE1376	0.0	1344.0	COG1391@1|root,COG2844@1|root,COG1391@2|Bacteria,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89	ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020	M00017,M00018	R00243,R01773,R01775	RC00006,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	GlnD_UR_UTase,GlnE,HD
SRR34280931_k127_681572_12	330214.NIDE1377	0.0	999.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR34280931_k127_681572_7	330214.NIDE1378	0.0	1042.0	COG0459@1|root,COG0459@2|Bacteria,3J0DA@40117|Nitrospirae	40117|Nitrospirae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR34280931_k127_681572_103	330214.NIDE1379	3.949e-56	198.0	COG0234@1|root,COG0234@2|Bacteria,3J0RF@40117|Nitrospirae	40117|Nitrospirae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR34280931_k127_681572_18	330214.NIDE1380	2.202e-283	876.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	pilL	-	-	ko:K02487,ko:K20276	ko02020,ko02024,map02020,map02024	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Collagen,FG-GAP_2,TcpQ
SRR34280931_k127_681572_95	1125863.JAFN01000001_gene2053	6.566e-70	255.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR34280931_k127_681572_28	330214.NIDE1382	2.351e-219	685.0	COG2223@1|root,COG2223@2|Bacteria,3J0YQ@40117|Nitrospirae	40117|Nitrospirae	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR34280931_k127_681572_25	330214.NIDE1383	1.126e-247	768.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR34280931_k127_681572_81	330214.NIDE1384	1.141e-88	295.0	COG0054@1|root,COG0054@2|Bacteria,3J0QT@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR34280931_k127_681572_82	330214.NIDE1385	6.324e-88	295.0	COG0781@1|root,COG0781@2|Bacteria,3J0RV@40117|Nitrospirae	40117|Nitrospirae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR34280931_k127_681572_21	330214.NIDE1386	7.819e-268	827.0	COG0015@1|root,COG0015@2|Bacteria,3J0EM@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR34280931_k127_681572_58	330214.NIDE1387	1.082e-120	394.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114	1.13.11.49	ko:K09162	-	-	-	-	ko00000,ko01000	-	-	-	Chlor_dismutase
SRR34280931_k127_681572_52	330214.NIDE1388	1.28e-142	455.0	COG0152@1|root,COG0152@2|Bacteria,3J0U6@40117|Nitrospirae	40117|Nitrospirae	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR34280931_k127_681572_117	330214.NIDE1390	1.615e-39	151.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR34280931_k127_681572_51	330214.NIDE1391	1.632e-145	463.0	COG0047@1|root,COG0047@2|Bacteria,3J10Q@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR34280931_k127_681572_2	330214.NIDE1392	0.0	1403.0	COG0046@1|root,COG0046@2|Bacteria,3J0TJ@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRR34280931_k127_681572_16	330214.NIDE1393	9.547e-301	923.0	COG0034@1|root,COG0034@2|Bacteria,3J0C5@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
SRR34280931_k127_681572_101	330214.NIDE1394	1.313e-57	203.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,TPR_19,TPR_8,Transglut_core
SRR34280931_k127_681572_38	330214.NIDE1396	2.883e-177	559.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
SRR34280931_k127_681572_26	330214.NIDE1397	8.167e-227	707.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR34280931_k127_681572_75	330214.NIDE1399	7.867e-96	316.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR34280931_k127_681572_65	330214.NIDE1401	1.058e-107	351.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
SRR34280931_k127_681572_41	330214.NIDE1402	1.266e-167	527.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE1402|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_22	330214.NIDE1407	2.716e-267	829.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02453,ko:K02660	ko02020,ko02025,ko03070,ko05111,map02020,map02025,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	ANAPC5,CarboxypepD_reg,HTH_18,OmpA,PD40,TPR_16,TPR_8,Wzy_C
SRR34280931_k127_681572_4	330214.NIDE1408	0.0	1342.0	COG1200@1|root,COG1200@2|Bacteria,3J0E8@40117|Nitrospirae	40117|Nitrospirae	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR34280931_k127_681572_55	330214.NIDE1410	2.981e-139	449.0	COG0248@1|root,COG0248@2|Bacteria,3J0K5@40117|Nitrospirae	40117|Nitrospirae	FP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR34280931_k127_681572_10	330214.NIDE1411	0.0	1005.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR34280931_k127_681572_104	330214.NIDE1412	1.148e-54	195.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
SRR34280931_k127_681572_66	330214.NIDE1415	9.902e-107	351.0	COG1750@1|root,COG1750@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lon_C,SdrD_B
SRR34280931_k127_681572_42	330214.NIDE1416	3.96e-167	531.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_3,Pentapeptide_4
SRR34280931_k127_681572_49	330214.NIDE1417	1.78e-151	481.0	COG1354@1|root,COG1354@2|Bacteria,3J13J@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR34280931_k127_681572_60	330214.NIDE1418	5.712e-116	380.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR34280931_k127_681572_0	330214.NIDE1420	0.0	2010.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,PA14
SRR34280931_k127_681572_15	330214.NIDE1421	1.861e-301	927.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,3J0A1@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR34280931_k127_681572_9	330214.NIDE1422	0.0	1030.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,3J0A2@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR34280931_k127_681572_33	330214.NIDE1423	5.69e-203	639.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR34280931_k127_681572_5	330214.NIDE1425	0.0	1135.0	COG0173@1|root,COG0173@2|Bacteria,3J0FR@40117|Nitrospirae	40117|Nitrospirae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR34280931_k127_681572_27	330214.NIDE1426	9.024e-222	690.0	COG0082@1|root,COG0082@2|Bacteria,3J0KQ@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR34280931_k127_681572_118	1476973.JMMB01000007_gene1361	4.857e-36	146.0	arCOG07807@1|root,32S82@2|Bacteria,1VE45@1239|Firmicutes,24BWC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
SRR34280931_k127_681572_84	330214.NIDE1427	4.485e-84	294.0	COG0328@1|root,COG0328@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	5_3_exonuc,5_3_exonuc_N,RNase_H
SRR34280931_k127_681572_57	330214.NIDE1428	3.06e-128	422.0	COG1119@1|root,COG1119@2|Bacteria	2|Bacteria	P	ATPase activity	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21,3.6.3.34	ko:K02013,ko:K02028,ko:K05776	ko02010,map02010	M00189,M00236,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.3	-	-	ABC_tran
SRR34280931_k127_681572_126	1538295.JY96_07110	3.28e-26	118.0	2ED69@1|root,3372Y@2|Bacteria,1NCE4@1224|Proteobacteria,2VXE8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_48	1218074.BAXZ01000012_gene2801	8.067e-152	494.0	COG0542@1|root,COG0542@2|Bacteria,1MXJT@1224|Proteobacteria,2VNEH@28216|Betaproteobacteria,1K1DM@119060|Burkholderiaceae	2|Bacteria	O	Belongs to the ClpA ClpB family	clpC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,Clp_N
SRR34280931_k127_681572_125	316055.RPE_2643	8.77e-28	130.0	2EI3D@1|root,33BUV@2|Bacteria,1NJU8@1224|Proteobacteria,2UMBX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_35	330214.NIDE1429	2.683e-195	616.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_681572_83	330214.NIDE1430	1.292e-86	291.0	COG3065@1|root,COG3065@2|Bacteria,3J1BB@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
SRR34280931_k127_681572_44	330214.NIDE1431	2.27e-160	509.0	COG2321@1|root,COG2321@2|Bacteria	2|Bacteria	S	Putative neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR34280931_k127_681572_79	330214.NIDE1434	1.974e-89	298.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR34280931_k127_681572_109	1396141.BATP01000027_gene1116	5.958e-49	181.0	COG0590@1|root,COG0590@2|Bacteria,46X47@74201|Verrucomicrobia,2IW17@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FJ	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR34280931_k127_681572_97	330214.NIDE1437	5.128e-68	234.0	2CIU5@1|root,33GNW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_681572_45	330214.NIDE1438	2.404e-157	505.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR34280931_k127_681572_19	330214.NIDE1439	2.485e-281	871.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.2,6.3.2.29,6.3.2.30,6.3.5.5	ko:K01919,ko:K01955,ko:K03802	ko00240,ko00250,ko00270,ko00480,ko01100,map00240,map00250,map00270,map00480,map01100	M00051,M00118	R00256,R00575,R00894,R01395,R10948,R10949,R10993	RC00002,RC00010,RC00043,RC00064,RC00090,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,ATP-grasp_4,ATPgrasp_ST,ATPgrasp_TupA,GH3,GSH-S_ATP,Glu_cys_ligase,RimK
SRR34280931_k127_681572_39	330214.NIDE1440	1.343e-173	552.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR34280931_k127_681572_29	330214.NIDE1441	1.9e-218	678.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	nia	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR34280931_k127_701748_0	330214.NIDE1304	0.0	2750.0	COG0086@1|root,COG0086@2|Bacteria,3J0BT@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR34280931_k127_701748_3	330214.NIDE1306	4.565e-73	246.0	COG0048@1|root,COG0048@2|Bacteria,3J0IU@40117|Nitrospirae	40117|Nitrospirae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR34280931_k127_701748_2	330214.NIDE1307	1.616e-98	322.0	COG0049@1|root,COG0049@2|Bacteria,3J0HK@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR34280931_k127_701748_1	330214.NIDE1308	0.0	1359.0	COG0480@1|root,COG0480@2|Bacteria,3J0EK@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR34280931_k127_701748_4	330214.NIDE1294	5.149e-21	92.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR34280931_k127_708267_49	1476583.DEIPH_ctg002orf0130	1.291e-23	104.0	2A20N@1|root,30QAJ@2|Bacteria,1WNAN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_708267_52	1476583.DEIPH_ctg002orf0130	3.201e-13	75.0	2A20N@1|root,30QAJ@2|Bacteria,1WNAN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_708267_21	330214.NIDE1559	4.348e-144	464.0	COG4395@1|root,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_08550	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	Tim44
SRR34280931_k127_708267_35	330214.NIDE1571	6.65e-89	294.0	COG0315@1|root,COG0315@2|Bacteria,3J0PN@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR34280931_k127_708267_46	330214.NIDE1572	4.682e-41	154.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR34280931_k127_708267_34	330214.NIDE1573	4.343e-89	294.0	COG0314@1|root,COG0314@2|Bacteria,3J1AN@40117|Nitrospirae	40117|Nitrospirae	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR34280931_k127_708267_8	330214.NIDE1574	5.554e-225	698.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
SRR34280931_k127_708267_24	330214.NIDE1575	5.892e-133	425.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	ureH	-	-	-	-	-	-	-	-	-	-	-	DsbD_2,NicO
SRR34280931_k127_708267_23	330214.NIDE1576	1.031e-142	456.0	COG1234@1|root,COG1234@2|Bacteria,3J14I@40117|Nitrospirae	40117|Nitrospirae	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR34280931_k127_708267_17	330214.NIDE1577	1.056e-173	545.0	COG0777@1|root,COG0777@2|Bacteria,3J0CK@40117|Nitrospirae	40117|Nitrospirae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR34280931_k127_708267_10	330214.NIDE1579	4.004e-213	668.0	COG0285@1|root,COG0285@2|Bacteria,3J0I6@40117|Nitrospirae	40117|Nitrospirae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR34280931_k127_708267_2	330214.NIDE1580	0.0	1562.0	COG1452@1|root,COG1452@2|Bacteria,3J0QI@40117|Nitrospirae	40117|Nitrospirae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRR34280931_k127_708267_41	330214.NIDE1582	6.688e-69	235.0	COG3118@1|root,COG3118@2|Bacteria,3J0P6@40117|Nitrospirae	40117|Nitrospirae	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR34280931_k127_708267_5	330214.NIDE1583	1.93e-283	878.0	COG0497@1|root,COG0497@2|Bacteria,3J0HU@40117|Nitrospirae	40117|Nitrospirae	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR34280931_k127_708267_11	330214.NIDE1584	2.612e-211	661.0	COG3437@1|root,COG3437@2|Bacteria,3J0ID@40117|Nitrospirae	2|Bacteria	T	response regulator	MA20_23615	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR34280931_k127_708267_4	330214.NIDE1585	1.325e-284	877.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	2|Bacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_708267_14	330214.NIDE1586	1.379e-192	609.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,dCache_1
SRR34280931_k127_708267_1	330214.NIDE1587	0.0	1675.0	COG0500@1|root,COG1073@1|root,COG2197@1|root,COG5000@1|root,COG1073@2|Bacteria,COG2197@2|Bacteria,COG2226@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	3.1.3.3	ko:K02038,ko:K02282,ko:K07018,ko:K07315	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035,ko02044,ko03021	3.A.1.7	-	-	GerE,HAMP,Hydrolase_4,Methyltransf_11,SpoIIE,dCache_1
SRR34280931_k127_708267_29	330214.NIDE1590	4.748e-111	368.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR34280931_k127_708267_25	330214.NIDE1591	1.583e-132	427.0	COG3359@1|root,COG3359@2|Bacteria,3J137@40117|Nitrospirae	40117|Nitrospirae	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
SRR34280931_k127_708267_38	330214.NIDE1592	1.021e-75	254.0	COG2164@1|root,COG2164@2|Bacteria,3J181@40117|Nitrospirae	40117|Nitrospirae	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
SRR34280931_k127_708267_44	330214.NIDE1593	1.344e-46	169.0	COG2952@1|root,COG2952@2|Bacteria,3J1ED@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
SRR34280931_k127_708267_45	330214.NIDE1594	2.857e-41	153.0	COG2952@1|root,COG2952@2|Bacteria,3J1DP@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
SRR34280931_k127_708267_40	330214.NIDE1595	4.118e-72	245.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE1595|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_708267_36	330214.NIDE1596	2.76e-86	286.0	COG1225@1|root,COG1225@2|Bacteria,3J13P@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR34280931_k127_708267_19	330214.NIDE1599	1.276e-157	500.0	COG0623@1|root,COG0623@2|Bacteria,3J11E@40117|Nitrospirae	40117|Nitrospirae	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR34280931_k127_708267_26	330214.NIDE1600	1.908e-127	415.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,PT-HINT,RHS_repeat
SRR34280931_k127_708267_30	247490.KSU1_C1712	9.882e-106	362.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_708267_57	1370125.AUWT01000015_gene2612	0.0008264	43.0	COG0454@1|root,COG0454@2|Bacteria,2IC6K@201174|Actinobacteria,235HM@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR34280931_k127_708267_9	330214.NIDE1620	1.409e-224	699.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
SRR34280931_k127_708267_20	330214.NIDE1621	7.097e-154	488.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
SRR34280931_k127_708267_18	330214.NIDE1622	4.074e-162	513.0	COG0555@1|root,COG0555@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysT	-	-	ko:K02018,ko:K02046	ko00920,ko02010,map00920,map02010	M00185,M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	-	BPD_transp_1
SRR34280931_k127_708267_15	330214.NIDE1623	1.963e-190	598.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SRR34280931_k127_708267_37	330214.NIDE1624	1.178e-84	281.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	cymR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR34280931_k127_708267_43	330214.NIDE1626	1.77e-58	203.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K19093	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR34280931_k127_708267_47	330214.NIDE1627	8.317e-39	145.0	2DR98@1|root,33ARN@2|Bacteria	2|Bacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR34280931_k127_708267_13	330214.NIDE1631	6.266e-205	638.0	COG0752@1|root,COG0752@2|Bacteria,3J0F5@40117|Nitrospirae	40117|Nitrospirae	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR34280931_k127_708267_3	330214.NIDE1632	0.0	1306.0	COG0751@1|root,COG0751@2|Bacteria,3J0F0@40117|Nitrospirae	40117|Nitrospirae	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR34280931_k127_708267_0	330214.NIDE1634	0.0	1766.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3J101@40117|Nitrospirae	40117|Nitrospirae	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR34280931_k127_708267_16	330214.NIDE1635	5.456e-189	600.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,3J0H2@40117|Nitrospirae	40117|Nitrospirae	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR34280931_k127_708267_6	330214.NIDE1636	3.425e-245	762.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Abhydrolase_8,DLH,Esterase,Peptidase_S9
SRR34280931_k127_708267_33	330214.NIDE1638	6.638e-96	317.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR34280931_k127_708267_7	330214.NIDE1639	1.63e-229	714.0	COG0477@1|root,COG2814@2|Bacteria,3J1DQ@40117|Nitrospirae	40117|Nitrospirae	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR34280931_k127_708267_27	330214.NIDE1641	6.491e-123	395.0	COG0307@1|root,COG0307@2|Bacteria,3J0PR@40117|Nitrospirae	40117|Nitrospirae	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR34280931_k127_708498_2	1408419.JHYG01000004_gene1262	2.514e-70	241.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2TS9I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
SRR34280931_k127_708498_4	396588.Tgr7_1775	2.29e-05	48.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
SRR34280931_k127_708498_5	573370.DMR_15210	2.578e-05	47.0	28M2G@1|root,2ZAGX@2|Bacteria,1QDCH@1224|Proteobacteria,42UN0@68525|delta/epsilon subdivisions,2WWWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR34280931_k127_708498_3	530564.Psta_1134	3.358e-32	132.0	2DSK4@1|root,33GG5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_708498_1	509191.AEDB02000023_gene3575	2.976e-115	385.0	COG0732@1|root,COG0732@2|Bacteria,1V78B@1239|Firmicutes,24K18@186801|Clostridia	186801|Clostridia	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
SRR34280931_k127_708498_0	192952.MM_2294	0.0	1093.0	COG0286@1|root,arCOG02632@2157|Archaea,2XUMY@28890|Euryarchaeota,2NAA3@224756|Methanomicrobia	224756|Methanomicrobia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR34280931_k127_734603_26	330214.NIDE2562	2.242e-173	552.0	COG0480@1|root,COG0480@2|Bacteria,3J0WU@40117|Nitrospirae	40117|Nitrospirae	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR34280931_k127_734603_38	330214.NIDE2563	5.179e-133	426.0	COG2003@1|root,COG2003@2|Bacteria,3J0HV@40117|Nitrospirae	40117|Nitrospirae	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR34280931_k127_734603_84	330214.NIDE2564	7.85e-28	121.0	2EI4B@1|root,33BVP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_47	330214.NIDE2565	2.02e-102	335.0	COG0742@1|root,COG0742@2|Bacteria,3J0V5@40117|Nitrospirae	40117|Nitrospirae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR34280931_k127_734603_49	330214.NIDE2566	1.187e-94	313.0	COG0669@1|root,COG0669@2|Bacteria,3J0MF@40117|Nitrospirae	40117|Nitrospirae	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR34280931_k127_734603_15	330214.NIDE2567	1.933e-237	738.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR34280931_k127_734603_78	330214.NIDE2568	6.967e-41	155.0	COG2331@1|root,COG2331@2|Bacteria,3J0V8@40117|Nitrospirae	40117|Nitrospirae	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR34280931_k127_734603_52	330214.NIDE2572	2.063e-84	287.0	COG0009@1|root,COG0009@2|Bacteria,3J0TD@40117|Nitrospirae	40117|Nitrospirae	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR34280931_k127_734603_14	330214.NIDE2573	1.826e-242	752.0	COG0151@1|root,COG0151@2|Bacteria,3J0H5@40117|Nitrospirae	40117|Nitrospirae	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR34280931_k127_734603_7	330214.NIDE2574	7.866e-321	984.0	COG0138@1|root,COG0138@2|Bacteria,3J0CV@40117|Nitrospirae	40117|Nitrospirae	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR34280931_k127_734603_36	330214.NIDE2575	1.011e-138	446.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02051,ko:K03286	-	M00188	-	-	ko00000,ko00002,ko02000	1.B.6,3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
SRR34280931_k127_734603_19	330214.NIDE2576	2.413e-202	636.0	COG1196@1|root,COG3743@1|root,COG1196@2|Bacteria,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K00185,ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	5.A.3	-	-	NrfD
SRR34280931_k127_734603_34	247490.KSU1_C0782	2.33e-141	462.0	COG3319@1|root,COG3319@2|Bacteria,2J09P@203682|Planctomycetes	203682|Planctomycetes	Q	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_24	247490.KSU1_C0781	1.425e-180	583.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR34280931_k127_734603_29	330214.NIDE2577	2.591e-163	522.0	COG3213@1|root,COG3213@2|Bacteria	2|Bacteria	P	Protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
SRR34280931_k127_734603_45	330214.NIDE2579	4.849e-109	361.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2579|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_5	330214.NIDE2581	0.0	1192.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_0	330214.NIDE2582	0.0	2221.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	40117|Nitrospirae	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR34280931_k127_734603_21	330214.NIDE2583	1.7e-199	623.0	COG0825@1|root,COG0825@2|Bacteria,3J0CN@40117|Nitrospirae	40117|Nitrospirae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR34280931_k127_734603_89	330214.NIDE2584	3.181e-12	70.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRR34280931_k127_734603_4	330214.NIDE2587	0.0	1424.0	COG1643@1|root,COG1643@2|Bacteria	2|Bacteria	L	helicase activity	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
SRR34280931_k127_734603_53	330214.NIDE2588	2.551e-84	287.0	COG2716@1|root,COG2716@2|Bacteria	2|Bacteria	E	regulation of RNA biosynthetic process	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
SRR34280931_k127_734603_57	330214.NIDE2589	4.474e-73	258.0	COG0242@1|root,COG0242@2|Bacteria,3J0RI@40117|Nitrospirae	40117|Nitrospirae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR34280931_k127_734603_66	330214.NIDE2590	1.172e-61	215.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF900,Sel1
SRR34280931_k127_734603_91	330214.NIDE2593	8.39e-06	48.0	2DCFZ@1|root,2ZDZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_42	330214.NIDE2595	7.442e-117	381.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR34280931_k127_734603_37	330214.NIDE2599	4.133e-135	438.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	bioH	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.11.1.10,2.1.1.197,3.1.1.85,3.3.2.9	ko:K00433,ko:K01253,ko:K02169,ko:K02170	ko00780,ko00980,ko01100,ko04976,ko05204,map00780,map00980,map01100,map04976,map05204	M00572	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443,R09543,R09725	RC00003,RC00460,RC00461,RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iBWG_1329.BWG_3103,iECBD_1354.ECBD_0333,iECDH10B_1368.ECDH10B_3587,iECDH1ME8569_1439.ECDH1ME8569_3291,iETEC_1333.ETEC_3662,iEcDH1_1363.EcDH1_0301,iJO1366.b3412,iY75_1357.Y75_RS20155	Abhydrolase_1,Abhydrolase_6
SRR34280931_k127_734603_61	864702.OsccyDRAFT_4243	2.021e-68	261.0	COG4191@1|root,COG4191@2|Bacteria,1G5TB@1117|Cyanobacteria,1HB2V@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_32	330214.NIDE0584	5.025e-160	535.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE8,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR34280931_k127_734603_71	330214.NIDE2605	5.788e-55	194.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF550,MazG-like
SRR34280931_k127_734603_65	330214.NIDE2619	1.944e-62	219.0	COG2453@1|root,COG2453@2|Bacteria	2|Bacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,Y_phosphatase
SRR34280931_k127_734603_41	1303518.CCALI_00699	2.56e-119	393.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR34280931_k127_734603_69	580332.Slit_2308	2.044e-60	226.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VX93@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
SRR34280931_k127_734603_64	330214.NIDE0434	6.986e-63	226.0	COG1686@1|root,COG1686@2|Bacteria,3J179@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR34280931_k127_734603_73	330214.NIDE1696	1.757e-45	177.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR34280931_k127_734603_43	1128421.JAGA01000002_gene936	5.269e-116	386.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362,ko:K07001	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3734,Patatin,Pyr_redox_2,Reductase_C
SRR34280931_k127_734603_11	330214.NIDE2613	9.06e-257	797.0	COG2262@1|root,COG2262@2|Bacteria,3J0AE@40117|Nitrospirae	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR34280931_k127_734603_85	330214.NIDE2614	6.118e-27	112.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218,ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin,UPF0066,YafQ_toxin
SRR34280931_k127_734603_74	330214.NIDE2615	7.449e-45	164.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K18830	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,TPR_12,TPR_8
SRR34280931_k127_734603_75	768671.ThimaDRAFT_1906	2.462e-44	166.0	2B1WT@1|root,31UCY@2|Bacteria,1NK5F@1224|Proteobacteria,1SUD8@1236|Gammaproteobacteria,1X1VV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_3	330214.NIDE2620	0.0	1480.0	COG4096@1|root,COG4096@2|Bacteria,3J18J@40117|Nitrospirae	2|Bacteria	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
SRR34280931_k127_734603_63	653733.Selin_2594	2.965e-65	226.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR34280931_k127_734603_28	653733.Selin_2593	1.691e-167	531.0	COG1256@1|root,COG1256@2|Bacteria	2|Bacteria	N	flagellar hook-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_39	555778.Hneap_0614	4.061e-121	403.0	COG0732@1|root,COG0732@2|Bacteria,1R4KU@1224|Proteobacteria,1SAJW@1236|Gammaproteobacteria,1WZAA@135613|Chromatiales	135613|Chromatiales	L	PFAM restriction modification system DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
SRR34280931_k127_734603_10	521674.Plim_2651	2.355e-272	842.0	COG0286@1|root,COG0286@2|Bacteria,2IXEQ@203682|Planctomycetes	203682|Planctomycetes	V	COG0286 Type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR34280931_k127_734603_87	518766.Rmar_1765	1.319e-16	82.0	COG2361@1|root,COG2361@2|Bacteria,4NV8D@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR34280931_k127_734603_93	102125.Xen7305DRAFT_00001740	0.0009967	46.0	COG2361@1|root,COG2361@2|Bacteria,1G9J5@1117|Cyanobacteria,3VKQ2@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR34280931_k127_734603_86	1123389.ATXJ01000028_gene897	1.334e-22	100.0	COG1669@1|root,COG1669@2|Bacteria,1WKPG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR34280931_k127_734603_92	323261.Noc_2939	1.726e-05	51.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR34280931_k127_734603_18	330214.NIDE1570	2.894e-204	644.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	NHL
SRR34280931_k127_734603_20	330214.NIDE1569	6.276e-201	634.0	COG1301@1|root,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SRR34280931_k127_734603_82	743299.Acife_1160	3.538e-31	128.0	2DPU2@1|root,333DK@2|Bacteria,1NCKZ@1224|Proteobacteria,1SEQE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR34280931_k127_734603_88	1283300.ATXB01000002_gene2960	1.493e-12	70.0	2EAHN@1|root,334KU@2|Bacteria,1NAT6@1224|Proteobacteria,1SD2M@1236|Gammaproteobacteria,1XGST@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_22	330214.NIDE2635	3.537e-199	622.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
SRR34280931_k127_734603_2	330214.NIDE2638	0.0	1705.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,3J0ZS@40117|Nitrospirae	40117|Nitrospirae	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR34280931_k127_734603_27	330214.NIDE2639	1.09e-169	537.0	COG1052@1|root,COG1052@2|Bacteria,3J13M@40117|Nitrospirae	40117|Nitrospirae	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR34280931_k127_734603_9	330214.NIDE2640	8.754e-302	936.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2640|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_734603_79	330214.NIDE2641	1.059e-40	150.0	COG1278@1|root,COG1278@2|Bacteria,3J0QZ@40117|Nitrospirae	40117|Nitrospirae	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR34280931_k127_734603_16	330214.NIDE2642	9.054e-214	668.0	COG0795@1|root,COG0795@2|Bacteria,3J0S0@40117|Nitrospirae	40117|Nitrospirae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR34280931_k127_734603_17	330214.NIDE2643	9.667e-209	651.0	COG0795@1|root,COG0795@2|Bacteria,3J0QQ@40117|Nitrospirae	40117|Nitrospirae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR34280931_k127_734603_13	330214.NIDE2644	2.062e-250	776.0	COG0304@1|root,COG0304@2|Bacteria,3J0DH@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR34280931_k127_734603_77	330214.NIDE2645	1.155e-41	156.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078,ko:K05553	ko00253,ko01056,ko01130,map00253,map01056,map01130	M00778	R06635,R06637,R06641,R06643,R06644,R06645,R09258,R09259,R10960,R11516	RC00004,RC00039,RC02545,RC02728,RC02729,RC02931,RC02932,RC02947	ko00000,ko00001,ko00002,ko01004,ko01008	-	-	-	PP-binding
SRR34280931_k127_734603_23	330214.NIDE2646	4.7e-198	625.0	COG1044@1|root,COG1044@2|Bacteria,3J0GQ@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SRR34280931_k127_734603_8	330214.NIDE2649	3.337e-315	979.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
SRR34280931_k127_734603_40	330214.NIDE2650	3.984e-120	394.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	cnpD3	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,HD_5
SRR34280931_k127_734603_30	330214.NIDE2651	2.931e-163	527.0	COG0784@1|root,COG1196@1|root,COG0784@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	asgA	-	-	ko:K02666,ko:K03497,ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022,ko02035,ko02044,ko03000,ko03036,ko04812	3.A.15.2	-	-	HATPase_c,HATPase_c_2,HisKA,HisKA_2,HisKA_3,Response_reg
SRR34280931_k127_734603_62	330214.NIDE2652	1.322e-67	233.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW	-	-	ko:K02659,ko:K03408,ko:K03415,ko:K11524	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	CheW
SRR34280931_k127_734603_1	330214.NIDE2654	0.0	1725.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,3J0WW@40117|Nitrospirae	40117|Nitrospirae	T	Two component signalling adaptor domain	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
SRR34280931_k127_734603_6	330214.NIDE2655	0.0	1073.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,3J11V@40117|Nitrospirae	40117|Nitrospirae	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal
SRR34280931_k127_734603_56	330214.NIDE2656	1.728e-74	254.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW2	-	-	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW
SRR34280931_k127_734603_58	330214.NIDE2657	2.325e-72	244.0	COG0745@1|root,COG0745@2|Bacteria,3J16K@40117|Nitrospirae	40117|Nitrospirae	T	cheY-homologous receiver domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
SRR34280931_k127_734603_35	330214.NIDE2658	4.452e-139	445.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
SRR34280931_k127_734603_12	330214.NIDE2659	6.34e-253	788.0	COG1492@1|root,COG1492@2|Bacteria,3J0F3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
SRR34280931_k127_734603_50	330214.NIDE2660	3.152e-94	315.0	COG1865@1|root,COG1865@2|Bacteria	2|Bacteria	HP	Adenosylcobinamide amidohydrolase	cbiZ	-	2.7.1.156,2.7.7.62,3.6.3.34	ko:K02013,ko:K02231	ko00860,ko01100,ko02010,map00860,map01100,map02010	M00122,M00240	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,CbiZ
SRR34280931_k127_734603_33	330214.NIDE2661	2.427e-154	496.0	COG0079@1|root,COG0079@2|Bacteria,3J138@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR34280931_k127_734603_31	330214.NIDE2662	2.605e-160	511.0	COG1270@1|root,COG1270@2|Bacteria,3J0K4@40117|Nitrospirae	40117|Nitrospirae	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cbiB	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR34280931_k127_734603_46	330214.NIDE2663	6.473e-109	361.0	COG0368@1|root,COG0368@2|Bacteria,3J0VC@40117|Nitrospirae	40117|Nitrospirae	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR34280931_k127_734603_25	330214.NIDE2664	2.586e-180	569.0	COG2038@1|root,COG2038@2|Bacteria,3J0C9@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR34280931_k127_734603_54	330214.NIDE2665	1.3e-79	269.0	COG2087@1|root,COG2087@2|Bacteria,3J0UG@40117|Nitrospirae	40117|Nitrospirae	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
SRR34280931_k127_734603_44	330214.NIDE2666	4.177e-111	361.0	COG2096@1|root,COG2096@2|Bacteria	2|Bacteria	S	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.2.1.88,1.5.5.2,2.5.1.17	ko:K00798,ko:K13821	ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130	M00122	R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268	RC00080,RC00083,RC00216,RC00242,RC00255,RC00533	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Cob_adeno_trans
SRR34280931_k127_734603_60	330214.NIDE2667	6.252e-69	234.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	bluB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.79,2.4.2.21	ko:K00768,ko:K04719	ko00740,ko00860,ko01100,map00740,map00860,map01100	M00122	R04148,R09083	RC00033,RC00063,RC00435,RC02413	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
SRR34280931_k127_748321_43	330214.NIDE0538	5.735e-137	439.0	COG0030@1|root,COG0030@2|Bacteria,3J0R6@40117|Nitrospirae	40117|Nitrospirae	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR34280931_k127_748321_65	338966.Ppro_3229	4.062e-88	303.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR34280931_k127_748321_22	330214.NIDE0535	1.368e-198	621.0	COG0530@1|root,COG0530@2|Bacteria,3J0V1@40117|Nitrospirae	40117|Nitrospirae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR34280931_k127_748321_16	330214.NIDE0534	1.048e-209	657.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR34280931_k127_748321_40	330214.NIDE0532	1.09e-144	461.0	COG1691@1|root,COG1691@2|Bacteria	2|Bacteria	C	(AIR) carboxylase	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR34280931_k127_748321_28	330214.NIDE0531	2.403e-177	559.0	COG0240@1|root,COG0240@2|Bacteria,3J0GP@40117|Nitrospirae	40117|Nitrospirae	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR34280931_k127_748321_39	330214.NIDE0529	2.057e-145	463.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Amidinotransf,Saccharop_dh_N
SRR34280931_k127_748321_11	330214.NIDE0528	1.062e-231	721.0	COG1915@1|root,COG1915@2|Bacteria	2|Bacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
SRR34280931_k127_748321_19	330214.NIDE0527	7.141e-207	645.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SRR34280931_k127_748321_31	330214.NIDE0525	4.627e-168	530.0	COG1408@1|root,COG1408@2|Bacteria,3J0SB@40117|Nitrospirae	40117|Nitrospirae	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR34280931_k127_748321_55	330214.NIDE0524	7.827e-107	349.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	4.4.1.31	ko:K02632	ko00196,map00196	-	-	-	ko00000,ko00001,ko00194,ko01000	-	-	-	HEAT_2,HEAT_PBS
SRR34280931_k127_748321_71	330214.NIDE0523	1.418e-78	264.0	COG1846@1|root,COG1846@2|Bacteria,3J14X@40117|Nitrospirae	40117|Nitrospirae	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_38	330214.NIDE0522	1.482e-146	472.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Lactamase_B_2
SRR34280931_k127_748321_30	330214.NIDE0521	3.432e-172	544.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR34280931_k127_748321_36	330214.NIDE0520	2.213e-153	487.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	ycf38	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR34280931_k127_748321_24	330214.NIDE0519	2.148e-189	597.0	COG1131@1|root,COG1131@2|Bacteria,3J0JF@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_748321_45	330214.NIDE0518	1.094e-132	424.0	COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae	40117|Nitrospirae	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRR34280931_k127_748321_25	330214.NIDE0517	1.884e-185	586.0	COG5621@1|root,COG5621@2|Bacteria,3J19I@40117|Nitrospirae	40117|Nitrospirae	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR34280931_k127_748321_23	330214.NIDE0516	8.835e-198	619.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR34280931_k127_748321_97	330214.NIDE0515	5.135e-44	164.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR34280931_k127_748321_102	330214.NIDE0515	1.152e-37	143.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR34280931_k127_748321_122	330214.NIDE1696	2.753e-05	52.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR34280931_k127_748321_32	330214.NIDE2213	4.035e-162	523.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR34280931_k127_748321_14	330214.NIDE2217	9.234e-216	679.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR34280931_k127_748321_8	330214.NIDE2219	4.931e-316	972.0	COG3497@1|root,COG3497@2|Bacteria	2|Bacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR34280931_k127_748321_54	330214.NIDE2220	1.852e-108	352.0	2DB76@1|root,2Z7JZ@2|Bacteria	2|Bacteria	S	phage tail region protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR34280931_k127_748321_58	330214.NIDE2221	5.928e-99	328.0	2AAD4@1|root,30ZP1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T4_baseplate
SRR34280931_k127_748321_21	330214.NIDE2223	6.005e-199	629.0	28PII@1|root,2ZC8H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR34280931_k127_748321_12	330214.NIDE2224	1.555e-229	728.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
SRR34280931_k127_748321_110	596153.Alide_1029	1.122e-26	127.0	COG3266@1|root,COG3266@2|Bacteria,1QYZW@1224|Proteobacteria,2WHUG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR34280931_k127_748321_116	502025.Hoch_4379	1.23e-08	64.0	2DT1R@1|root,33IA4@2|Bacteria,1NI27@1224|Proteobacteria	1224|Proteobacteria	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
SRR34280931_k127_748321_42	330214.NIDE2228	8.994e-140	464.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4157,OmpA
SRR34280931_k127_748321_50	330214.NIDE2229	2.377e-118	383.0	2CI52@1|root,2ZC5H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_106	1215092.PA6_046_00120	1.665e-29	123.0	COG1652@1|root,COG1652@2|Bacteria,1N0XA@1224|Proteobacteria,1SC15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_15	330214.NIDE2231	4.323e-213	665.0	COG3500@1|root,COG3500@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	-
SRR34280931_k127_748321_57	330214.NIDE2232	8.038e-103	336.0	COG3501@1|root,COG3501@2|Bacteria	2|Bacteria	T	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR34280931_k127_748321_87	330214.NIDE2233	1.44e-56	200.0	2CE1N@1|root,32RYY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_81	330214.NIDE2234	8.09e-61	212.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR34280931_k127_748321_2	330214.NIDE2235	0.0	1384.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	yqbT1	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR34280931_k127_748321_4	330214.NIDE2236	0.0	1278.0	COG2375@1|root,COG2375@2|Bacteria	2|Bacteria	P	cellular response to nickel ion	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,FAD_binding_9,SIP
SRR34280931_k127_748321_7	330214.NIDE2237	0.0	1224.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Tail_P2_I
SRR34280931_k127_748321_0	330214.NIDE2238	0.0	2082.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR34280931_k127_748321_101	1121022.ABENE_19200	2.824e-39	149.0	2DJBU@1|root,32UCQ@2|Bacteria,1N6AP@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR34280931_k127_748321_88	330214.NIDE2814	2.48e-56	201.0	COG0607@1|root,COG0607@2|Bacteria,3J1F1@40117|Nitrospirae	40117|Nitrospirae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR34280931_k127_748321_33	330214.NIDE2795	6.56e-158	504.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_6,HTH_18
SRR34280931_k127_748321_47	330214.NIDE2794	1.928e-127	415.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR34280931_k127_748321_96	330214.NIDE2793	1.899e-45	167.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR34280931_k127_748321_70	330214.NIDE3050	6.428e-81	283.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR34280931_k127_748321_52	330214.NIDE2802	6.495e-111	362.0	28NM7@1|root,2ZBMT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
SRR34280931_k127_748321_75	497964.CfE428DRAFT_6579	1.711e-76	258.0	COG3832@1|root,COG3832@2|Bacteria,46SRI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR34280931_k127_748321_9	330214.NIDE2807	3.027e-285	886.0	COG0469@1|root,COG0469@2|Bacteria,3J0XM@40117|Nitrospirae	2|Bacteria	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR34280931_k127_748321_37	1267533.KB906734_gene4243	3.357e-148	481.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR34280931_k127_748321_46	330214.NIDE2799	4.691e-131	420.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Hexapep
SRR34280931_k127_748321_80	1144275.COCOR_03588	1.092e-63	226.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,42RGG@68525|delta/epsilon subdivisions,2X6F0@28221|Deltaproteobacteria,2YXND@29|Myxococcales	28221|Deltaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR34280931_k127_748321_73	1957.JODX01000009_gene2578	5.976e-78	265.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (isoleucine patch	maa	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
SRR34280931_k127_748321_59	330214.NIDE2788	5.623e-98	321.0	2EBKA@1|root,335KQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_90	330214.NIDE2813	2e-50	184.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR34280931_k127_748321_100	1122135.KB893146_gene1445	2.712e-39	149.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,2UCP4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	yybR	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR34280931_k127_748321_44	1123269.NX02_07415	1.042e-136	440.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2K1EG@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR34280931_k127_748321_95	485913.Krac_0295	1.261e-45	171.0	COG1651@1|root,COG1651@2|Bacteria,2G9C9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR34280931_k127_748321_119	929558.SMGD1_2377	3.911e-06	50.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2YPMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	Cj0420	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR34280931_k127_748321_92	479434.Sthe_1772	3.123e-50	187.0	COG1028@1|root,COG1028@2|Bacteria,2G8JD@200795|Chloroflexi,27YCF@189775|Thermomicrobia	189775|Thermomicrobia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR34280931_k127_748321_35	330214.NIDE3475	2.427e-154	496.0	COG0845@1|root,COG0845@2|Bacteria,3J10X@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR34280931_k127_748321_1	330214.NIDE3474	0.0	1568.0	COG0841@1|root,COG0841@2|Bacteria,3J0FA@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138,ko:K19585	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00767	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.47	-	-	ACR_tran
SRR34280931_k127_748321_29	1288494.EBAPG3_430	2.299e-174	563.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,372JJ@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRR34280931_k127_748321_83	1336233.JAEH01000055_gene4125	4.257e-60	219.0	COG0491@1|root,COG0491@2|Bacteria,1PBSA@1224|Proteobacteria,1SWGM@1236|Gammaproteobacteria,2QE2R@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR34280931_k127_748321_107	330214.NIDE0025	8.287e-29	119.0	COG2910@1|root,COG2910@2|Bacteria	2|Bacteria	S	NAD(P)H-binding	-	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
SRR34280931_k127_748321_77	47839.CCAU010000009_gene1521	2.802e-74	257.0	COG2227@1|root,COG2227@2|Bacteria,2H167@201174|Actinobacteria,23CXP@1762|Mycobacteriaceae	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR34280931_k127_748321_85	195522.BD01_0431	6.647e-58	211.0	COG0426@1|root,arCOG00506@2157|Archaea,2Y2IU@28890|Euryarchaeota,243XD@183968|Thermococci	183968|Thermococci	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR34280931_k127_748321_111	243090.RB2408	1.164e-23	109.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR34280931_k127_748321_74	1120705.FG95_01303	1.679e-77	267.0	2CK2M@1|root,32SBE@2|Bacteria,1PQG9@1224|Proteobacteria,2UXPB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_115	1210884.HG799478_gene15498	7.144e-14	72.0	COG1598@1|root,COG1598@2|Bacteria,2J4N9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_108	330214.NIDE1072	1.151e-27	113.0	2DP6Q@1|root,330SE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_99	330214.NIDE1071	2.051e-43	159.0	2E46S@1|root,32Z2Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_748321_6	330214.NIDE2781	0.0	1230.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
SRR34280931_k127_748321_5	330214.NIDE2780	0.0	1263.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
SRR34280931_k127_748321_10	330214.NIDE2778	4.011e-267	824.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR34280931_k127_748321_26	330214.NIDE2777	1.375e-181	571.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR34280931_k127_748321_20	330214.NIDE2776	1.329e-206	644.0	COG0604@1|root,COG0604@2|Bacteria,3J13T@40117|Nitrospirae	40117|Nitrospirae	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR34280931_k127_748321_76	330214.NIDE2775	4.835e-75	254.0	COG2905@1|root,COG2905@2|Bacteria,3J1AQ@40117|Nitrospirae	40117|Nitrospirae	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR34280931_k127_748321_62	330214.NIDE2773	5.277e-91	301.0	COG0521@1|root,COG0521@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR34280931_k127_748321_79	330214.NIDE2772	2.396e-67	229.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx4	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR34280931_k127_748321_60	330214.NIDE2770	2.363e-94	311.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT,Gamma_PGA_hydro
SRR34280931_k127_748321_109	886293.Sinac_1574	9.15e-27	113.0	COG2146@1|root,COG2146@2|Bacteria,2J0ZZ@203682|Planctomycetes	203682|Planctomycetes	P	COG2146 Ferredoxin subunits of nitrite reductase and	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR34280931_k127_748321_48	330214.NIDE2766	1.077e-120	387.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR34280931_k127_748321_67	330214.NIDE2765	9.715e-84	282.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	cycH	-	3.4.21.105	ko:K02200,ko:K04018,ko:K19225,ko:K20543,ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.55.3	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SRR34280931_k127_748321_51	330214.NIDE2764	1.149e-115	376.0	COG1648@1|root,COG1648@2|Bacteria	2|Bacteria	H	precorrin-2 dehydrogenase activity	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
SRR34280931_k127_748321_89	330214.NIDE2763	9.822e-55	197.0	COG0011@1|root,COG0011@2|Bacteria,3J0QD@40117|Nitrospirae	40117|Nitrospirae	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR34280931_k127_748321_27	330214.NIDE2761	3.107e-179	570.0	COG0787@1|root,COG0787@2|Bacteria,3J0JH@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR34280931_k127_748321_56	330214.NIDE2760	3.683e-105	343.0	COG0233@1|root,COG0233@2|Bacteria,3J0KJ@40117|Nitrospirae	40117|Nitrospirae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR34280931_k127_748321_41	330214.NIDE2759	2.585e-143	458.0	COG0528@1|root,COG0528@2|Bacteria,3J0BE@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR34280931_k127_748321_49	330214.NIDE2758	2.914e-120	387.0	COG0264@1|root,COG0264@2|Bacteria,3J0I2@40117|Nitrospirae	40117|Nitrospirae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR34280931_k127_748321_34	330214.NIDE2757	2.688e-157	498.0	COG0052@1|root,COG0052@2|Bacteria,3J0G9@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR34280931_k127_748321_13	330214.NIDE2756	1.017e-221	692.0	COG1364@1|root,COG1364@2|Bacteria,3J0B5@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR34280931_k127_748321_17	330214.NIDE2755	9.545e-208	648.0	COG0002@1|root,COG0002@2|Bacteria,3J0H9@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR34280931_k127_748321_78	330214.NIDE2754	1.823e-71	242.0	COG0103@1|root,COG0103@2|Bacteria,3J0N4@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR34280931_k127_748321_69	330214.NIDE2753	3.007e-81	271.0	COG0102@1|root,COG0102@2|Bacteria,3J0NE@40117|Nitrospirae	40117|Nitrospirae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR34280931_k127_748321_66	330214.NIDE2752	7.82e-86	285.0	COG1259@1|root,COG1259@2|Bacteria,3J0RC@40117|Nitrospirae	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
SRR34280931_k127_751166_69	330214.NIDE0867	1.931e-67	231.0	COG4775@1|root,COG4775@2|Bacteria,3J10P@40117|Nitrospirae	40117|Nitrospirae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SRR34280931_k127_751166_59	330214.NIDE0866	3.935e-111	362.0	COG2854@1|root,COG2854@2|Bacteria,3J13Z@40117|Nitrospirae	40117|Nitrospirae	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR34280931_k127_751166_65	330214.NIDE0865	1.354e-82	276.0	COG1463@1|root,COG1463@2|Bacteria,3J191@40117|Nitrospirae	40117|Nitrospirae	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR34280931_k127_751166_47	330214.NIDE0864	4.068e-141	450.0	COG1127@1|root,COG1127@2|Bacteria,3J0J2@40117|Nitrospirae	40117|Nitrospirae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR34280931_k127_751166_42	330214.NIDE0863	8.078e-150	479.0	COG0767@1|root,COG0767@2|Bacteria,3J0I7@40117|Nitrospirae	40117|Nitrospirae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR34280931_k127_751166_52	330214.NIDE0862	1.749e-128	414.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	MA20_16045	-	1.17.7.4,3.2.2.9	ko:K01243,ko:K03527	ko00270,ko00900,ko01100,ko01110,ko01130,ko01230,map00270,map00900,map01100,map01110,map01130,map01230	M00034,M00096,M00609	R00194,R01401,R05884,R08210	RC00063,RC00318,RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR34280931_k127_751166_2	330214.NIDE0861	0.0	1421.0	COG1657@1|root,COG1657@2|Bacteria,3J0ZD@40117|Nitrospirae	40117|Nitrospirae	I	Squalene-hopene cyclase C-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR34280931_k127_751166_0	330214.NIDE0860	0.0	2077.0	COG1196@1|root,COG1196@2|Bacteria,3J0W4@40117|Nitrospirae	40117|Nitrospirae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
SRR34280931_k127_751166_24	330214.NIDE0859	8.677e-205	638.0	COG0761@1|root,COG0761@2|Bacteria,3J0PP@40117|Nitrospirae	40117|Nitrospirae	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR34280931_k127_751166_44	330214.NIDE0858	1.947e-145	463.0	COG0745@1|root,COG0745@2|Bacteria,3J0JU@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR34280931_k127_751166_9	330214.NIDE0857	0.0	1075.0	COG5002@1|root,COG5002@2|Bacteria,3J0I0@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
SRR34280931_k127_751166_60	335543.Sfum_2275	9.606e-98	329.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,2MRD9@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR34280931_k127_751166_54	330214.NIDE0855	1.04e-121	393.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR34280931_k127_751166_36	330214.NIDE0854	3.265e-165	525.0	COG0332@1|root,COG0332@2|Bacteria,3J0FW@40117|Nitrospirae	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR34280931_k127_751166_40	330214.NIDE0853	5.284e-154	490.0	COG4105@1|root,COG4105@2|Bacteria,3J0UU@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR34280931_k127_751166_29	330214.NIDE0852	2.806e-190	601.0	COG0644@1|root,COG0644@2|Bacteria,3J0UE@40117|Nitrospirae	40117|Nitrospirae	C	oxidoreductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR34280931_k127_751166_43	330214.NIDE0851	3.692e-148	470.0	COG0785@1|root,COG0785@2|Bacteria,3J0KU@40117|Nitrospirae	40117|Nitrospirae	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR34280931_k127_751166_63	330214.NIDE0850	2.19e-91	304.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR34280931_k127_751166_56	330214.NIDE0849	6.825e-119	383.0	COG0526@1|root,COG0526@2|Bacteria,3J0SG@40117|Nitrospirae	40117|Nitrospirae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR34280931_k127_751166_25	330214.NIDE0848	2.315e-197	615.0	COG0755@1|root,COG0755@2|Bacteria,3J0NY@40117|Nitrospirae	40117|Nitrospirae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR34280931_k127_751166_12	330214.NIDE0847	1.222e-303	932.0	COG1333@1|root,COG1333@2|Bacteria,3J0N7@40117|Nitrospirae	40117|Nitrospirae	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR34280931_k127_751166_20	330214.NIDE0846	2.567e-244	756.0	COG0192@1|root,COG0192@2|Bacteria,3J0A4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR34280931_k127_751166_14	330214.NIDE0845	1.486e-269	832.0	COG0499@1|root,COG0499@2|Bacteria,3J0AH@40117|Nitrospirae	40117|Nitrospirae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR34280931_k127_751166_90	1283299.AUKG01000002_gene4555	8.068e-05	48.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR34280931_k127_751166_87	661478.OP10G_3870	9.422e-15	78.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR34280931_k127_751166_10	330214.NIDE0843	0.0	1074.0	COG1032@1|root,COG1032@2|Bacteria,3J18Y@40117|Nitrospirae	40117|Nitrospirae	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR34280931_k127_751166_33	330214.NIDE0841	1.611e-182	572.0	COG0074@1|root,COG0074@2|Bacteria,3J0WZ@40117|Nitrospirae	40117|Nitrospirae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR34280931_k127_751166_19	330214.NIDE0840	5.454e-245	759.0	COG0045@1|root,COG0045@2|Bacteria,3J0ZB@40117|Nitrospirae	40117|Nitrospirae	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR34280931_k127_751166_11	330214.NIDE0839	0.0	1041.0	COG0029@1|root,COG0029@2|Bacteria,3J0WB@40117|Nitrospirae	40117|Nitrospirae	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR34280931_k127_751166_39	330214.NIDE0838	2.666e-155	492.0	COG1152@1|root,COG1152@2|Bacteria,3J11C@40117|Nitrospirae	40117|Nitrospirae	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_751166_5	330214.NIDE0837	0.0	1283.0	COG2838@1|root,COG2838@2|Bacteria	2|Bacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
SRR34280931_k127_751166_3	330214.NIDE0836	0.0	1409.0	COG1048@1|root,COG1048@2|Bacteria,3J0E6@40117|Nitrospirae	40117|Nitrospirae	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR34280931_k127_751166_6	330214.NIDE0835	0.0	1200.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.8,6.2.1.5	ko:K01902,ko:K15230,ko:K15233	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00352,R00405,R01322,R02404	RC00004,RC00014,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0306	Citrate_synt,CoA_binding,Ligase_CoA,Succ_CoA_lig
SRR34280931_k127_751166_17	330214.NIDE0834	3.779e-255	788.0	COG0045@1|root,COG0045@2|Bacteria,3J185@40117|Nitrospirae	40117|Nitrospirae	H	ATP citrate lyase citrate-binding	-	-	2.3.3.8	ko:K15231	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
SRR34280931_k127_751166_50	330214.NIDE0833	1.558e-135	439.0	COG0266@1|root,COG0266@2|Bacteria,3J17X@40117|Nitrospirae	40117|Nitrospirae	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR34280931_k127_751166_71	330214.NIDE0832	5.038e-66	228.0	COG2453@1|root,COG2453@2|Bacteria	2|Bacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
SRR34280931_k127_751166_34	330214.NIDE0829	7.813e-171	544.0	COG5459@1|root,COG5459@2|Bacteria,3J16W@40117|Nitrospirae	40117|Nitrospirae	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
SRR34280931_k127_751166_13	330214.NIDE0827	9.661e-278	856.0	COG0674@1|root,COG0674@2|Bacteria,3J105@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR34280931_k127_751166_37	330214.NIDE0826	1.244e-161	509.0	COG0226@1|root,COG0226@2|Bacteria,3J0YH@40117|Nitrospirae	2|Bacteria	P	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	forD	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	CO_dh,PBP_like_2
SRR34280931_k127_751166_72	330214.NIDE0825	5.519e-66	225.0	COG1144@1|root,COG1144@2|Bacteria,3J1A9@40117|Nitrospirae	40117|Nitrospirae	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_751166_41	330214.NIDE0824	1.237e-151	479.0	COG1014@1|root,COG1014@2|Bacteria,3J0YE@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SRR34280931_k127_751166_26	330214.NIDE0823	2.664e-196	614.0	COG1013@1|root,COG1013@2|Bacteria,3J10F@40117|Nitrospirae	2|Bacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	forB2	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR34280931_k127_751166_68	330214.NIDE0820	1.871e-74	251.0	COG0780@1|root,COG0780@2|Bacteria,3J0R4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR34280931_k127_751166_18	330214.NIDE0819	2.123e-246	767.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	omp-1X	-	-	ko:K12976,ko:K22110	-	-	-	-	ko00000,ko01000,ko01005,ko02000	1.B.35.1,1.B.35.2	-	-	DUF2490,OMP_b-brl,Surface_Ag_2
SRR34280931_k127_751166_57	330214.NIDE0818	2.771e-117	386.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	moxG	-	-	ko:K00406,ko:K16255	ko00190,ko00680,ko01100,ko01120,ko02020,map00190,map00680,map01100,map01120,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
SRR34280931_k127_751166_61	330214.NIDE0817	2.998e-95	319.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,fn3_3
SRR34280931_k127_751166_7	330214.NIDE0816	0.0	1180.0	COG0745@1|root,COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,CHASE8,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR34280931_k127_751166_8	330214.NIDE0815	0.0	1120.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG3829@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
SRR34280931_k127_751166_48	330214.NIDE0814	3.622e-140	449.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074	Metallophos
SRR34280931_k127_751166_74	330214.NIDE0813	5.031e-61	216.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR34280931_k127_751166_49	330214.NIDE0812	2.746e-139	447.0	COG0413@1|root,COG0413@2|Bacteria,3J0GX@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR34280931_k127_751166_30	330214.NIDE0811	7.942e-188	587.0	COG0685@1|root,COG0685@2|Bacteria,3J0I8@40117|Nitrospirae	40117|Nitrospirae	C	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
SRR34280931_k127_751166_38	330214.NIDE0810	2.063e-160	509.0	COG0190@1|root,COG0190@2|Bacteria,3J0FT@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR34280931_k127_751166_32	330214.NIDE0809	1.034e-184	585.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
SRR34280931_k127_751166_46	330214.NIDE0808	2.135e-144	458.0	2EGFY@1|root,33A7X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_751166_15	330214.NIDE0807	5.19e-259	809.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,CHASE,EAL,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
SRR34280931_k127_751166_27	330214.NIDE0806	4.251e-195	613.0	COG3287@1|root,COG3287@2|Bacteria	2|Bacteria	M	FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR34280931_k127_751166_1	330214.NIDE0805	0.0	1834.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR34280931_k127_751166_22	330214.NIDE0804	7.449e-224	702.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K03407,ko:K07678,ko:K14978	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506,M00663	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
SRR34280931_k127_751166_31	330214.NIDE0803	2.554e-185	582.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
SRR34280931_k127_751166_53	330214.NIDE0801	7.105e-123	398.0	COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae	40117|Nitrospirae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR34280931_k127_751166_51	330214.NIDE0800	2.305e-132	424.0	COG0571@1|root,COG0571@2|Bacteria,3J119@40117|Nitrospirae	40117|Nitrospirae	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	-	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR34280931_k127_751166_16	330214.NIDE0799	1.651e-258	798.0	COG0304@1|root,COG0304@2|Bacteria,3J0DH@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR34280931_k127_751166_78	330214.NIDE0798	3.655e-37	142.0	COG0236@1|root,COG0236@2|Bacteria,3J0RX@40117|Nitrospirae	40117|Nitrospirae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR34280931_k127_751166_45	330214.NIDE0797	4.522e-145	461.0	COG1028@1|root,COG1028@2|Bacteria,3J0J6@40117|Nitrospirae	40117|Nitrospirae	IQ	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR34280931_k127_751166_35	330214.NIDE0796	1.002e-169	537.0	COG0331@1|root,COG0331@2|Bacteria,3J0IX@40117|Nitrospirae	40117|Nitrospirae	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR34280931_k127_751166_28	330214.NIDE0795	2.082e-193	606.0	COG0332@1|root,COG0332@2|Bacteria,3J0FW@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR34280931_k127_751166_23	330214.NIDE0794	2.436e-209	652.0	COG0416@1|root,COG0416@2|Bacteria,3J0DY@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR34280931_k127_751166_86	500633.CLOHIR_01133	3.202e-15	77.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR34280931_k127_751166_62	330214.NIDE0792	3.83e-95	319.0	COG1399@1|root,COG1399@2|Bacteria,3J0UQ@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR34280931_k127_751166_81	483219.LILAB_33350	6.143e-23	100.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR34280931_k127_751166_67	330214.NIDE0790	1.176e-77	261.0	COG0629@1|root,COG0629@2|Bacteria,3J0NB@40117|Nitrospirae	40117|Nitrospirae	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR34280931_k127_751166_82	1121403.AUCV01000002_gene626	3.302e-21	98.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,2MKEY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR34280931_k127_751166_70	1254432.SCE1572_32710	6.982e-67	249.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,42Z9W@68525|delta/epsilon subdivisions,2WUMZ@28221|Deltaproteobacteria,2YTTR@29|Myxococcales	28221|Deltaproteobacteria	C	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
SRR34280931_k127_751166_79	395495.Lcho_3891	9.708e-34	139.0	COG1999@1|root,COG1999@2|Bacteria,1REUE@1224|Proteobacteria,2WA2J@28216|Betaproteobacteria,1KNIJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR34280931_k127_751166_55	395495.Lcho_2626	1.558e-120	411.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_751166_4	1242864.D187_009357	0.0	1345.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria,437UT@68525|delta/epsilon subdivisions,2WYPB@28221|Deltaproteobacteria,2YUNB@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR34280931_k127_751166_66	1172188.KB911825_gene3643	1.411e-80	288.0	COG3291@1|root,COG3291@2|Bacteria,2H2KA@201174|Actinobacteria,4FIPX@85021|Intrasporangiaceae	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_751166_58	330214.NIDE0786	4.347e-115	373.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	CBP_BcsS,OMP_b-brl
SRR34280931_k127_751166_21	330214.NIDE0784	1.715e-236	734.0	COG5274@1|root,COG5274@2|Bacteria	2|Bacteria	C	heme binding	-	-	1.13.11.52	ko:K00463	ko00380,ko01100,ko05143,map00380,map01100,map05143	M00038	R00678,R02702,R02909,R03628	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,FAD_binding_1,IDO,NAD_binding_1
SRR34280931_k127_752435_0	330214.NIDE3290	5.099e-245	760.0	COG0018@1|root,COG0018@2|Bacteria,3J0A8@40117|Nitrospirae	40117|Nitrospirae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR34280931_k127_752435_1	330214.NIDE3289	1.01e-235	730.0	COG0343@1|root,COG0343@2|Bacteria,3J0DU@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR34280931_k127_757733_8	330214.NIDE2550	4.624e-151	480.0	COG0161@1|root,COG0161@2|Bacteria,3J0D9@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR34280931_k127_757733_4	330214.NIDE2548	7.765e-197	618.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR34280931_k127_757733_7	330214.NIDE2547	1.605e-151	482.0	COG1912@1|root,COG1912@2|Bacteria,3J0RG@40117|Nitrospirae	40117|Nitrospirae	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR34280931_k127_757733_11	330214.NIDE2546	2.772e-89	296.0	COG0782@1|root,COG0782@2|Bacteria,3J0NA@40117|Nitrospirae	40117|Nitrospirae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR34280931_k127_757733_0	330214.NIDE2545	0.0	2054.0	COG0458@1|root,COG0458@2|Bacteria,3J0BC@40117|Nitrospirae	40117|Nitrospirae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR34280931_k127_757733_5	330214.NIDE2544	1.656e-195	611.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR34280931_k127_757733_10	247490.KSU1_C0729	7.612e-99	335.0	COG0616@1|root,COG0616@2|Bacteria,2IYKF@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR34280931_k127_757733_2	330214.NIDE2542	1.581e-241	749.0	COG0505@1|root,COG0505@2|Bacteria,3J0CS@40117|Nitrospirae	40117|Nitrospirae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR34280931_k127_757733_1	330214.NIDE2540	2.343e-260	805.0	COG0044@1|root,COG0044@2|Bacteria,3J0D7@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR34280931_k127_757733_6	330214.NIDE2539	9.254e-178	560.0	COG0540@1|root,COG0540@2|Bacteria,3J0FJ@40117|Nitrospirae	40117|Nitrospirae	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR34280931_k127_757733_9	330214.NIDE2538	3.106e-111	362.0	COG2065@1|root,COG2065@2|Bacteria,3J0JX@40117|Nitrospirae	40117|Nitrospirae	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR34280931_k127_757733_13	330214.NIDE2536	1.65e-48	178.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR34280931_k127_778296_57	330214.NIDE1042	3.326e-10	62.0	COG4122@1|root,COG4122@2|Bacteria,3J1C3@40117|Nitrospirae	40117|Nitrospirae	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_778296_7	330214.NIDE1041	1.777e-300	925.0	COG2317@1|root,COG2317@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	ypwA	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.17.19	ko:K01299,ko:K03281	-	-	-	-	ko00000,ko01000,ko01002	2.A.49	-	-	Peptidase_M32
SRR34280931_k127_778296_34	330214.NIDE1040	9.042e-108	355.0	COG2197@1|root,COG2197@2|Bacteria,3J12Q@40117|Nitrospirae	2|Bacteria	K	Product type r regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_778296_39	330214.NIDE1037	1.26e-94	310.0	COG0735@1|root,COG0735@2|Bacteria,3J0UN@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR34280931_k127_778296_18	330214.NIDE1036	5.608e-191	601.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	fbpA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	iJN678.sufA	SBP_bac_6,SBP_bac_8
SRR34280931_k127_778296_8	330214.NIDE1035	5.563e-300	925.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	sfuB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR34280931_k127_778296_16	330214.NIDE1034	2.439e-204	640.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	potA	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR34280931_k127_778296_45	330214.NIDE1033	4.938e-78	262.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR34280931_k127_778296_56	1172190.M947_11485	1.597e-14	78.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2YQ7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR34280931_k127_778296_49	330214.NIDE1031	4.081e-51	194.0	COG0810@1|root,COG0810@2|Bacteria,3J0U0@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR34280931_k127_778296_22	330214.NIDE1029	1.458e-166	530.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	nosX	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR34280931_k127_778296_59	1297742.A176_03639	3.704e-07	53.0	2BR48@1|root,32K27@2|Bacteria,1Q2KM@1224|Proteobacteria,43878@68525|delta/epsilon subdivisions,2X3H6@28221|Deltaproteobacteria,2YW2M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_778296_21	330214.NIDE0994	7.494e-171	552.0	COG1730@1|root,COG1730@2|Bacteria	2|Bacteria	O	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_778296_44	330214.NIDE1026	8.255e-85	287.0	COG3901@1|root,COG3901@2|Bacteria	2|Bacteria	CK	FMN binding	nosR	-	-	ko:K19339,ko:K19343	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
SRR34280931_k127_778296_41	330214.NIDE1024	1.287e-90	304.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD,HD_5
SRR34280931_k127_778296_46	330214.NIDE1023	6.907e-72	247.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	AraC_binding,HTH_18,HTH_AraC,Response_reg
SRR34280931_k127_778296_43	330214.NIDE1022	4.215e-85	284.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR34280931_k127_778296_40	330214.NIDE1021	8.805e-92	302.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR34280931_k127_778296_0	330214.NIDE1020	0.0	1491.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,3J0DN@40117|Nitrospirae	40117|Nitrospirae	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR34280931_k127_778296_19	330214.NIDE1019	1.861e-183	579.0	COG0758@1|root,COG0758@2|Bacteria,3J0Q8@40117|Nitrospirae	40117|Nitrospirae	L	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRR34280931_k127_778296_5	330214.NIDE1018	6.64e-321	985.0	COG1530@1|root,COG1530@2|Bacteria,3J0DK@40117|Nitrospirae	40117|Nitrospirae	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR34280931_k127_778296_10	330214.NIDE1017	1.194e-225	702.0	COG0772@1|root,COG0772@2|Bacteria,3J0IA@40117|Nitrospirae	40117|Nitrospirae	D	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR34280931_k127_778296_2	330214.NIDE1016	0.0	1165.0	COG0768@1|root,COG0768@2|Bacteria,3J0FY@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR34280931_k127_778296_23	330214.NIDE1014	1.072e-164	520.0	COG1792@1|root,COG1792@2|Bacteria,3J0S3@40117|Nitrospirae	40117|Nitrospirae	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR34280931_k127_778296_12	330214.NIDE1013	1.532e-217	676.0	COG1077@1|root,COG1077@2|Bacteria,3J0BS@40117|Nitrospirae	40117|Nitrospirae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR34280931_k127_778296_36	330214.NIDE1012	7.556e-103	337.0	COG1714@1|root,COG1714@2|Bacteria,3J0U3@40117|Nitrospirae	40117|Nitrospirae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR34280931_k127_778296_54	1121440.AUMA01000015_gene1835	2.1e-19	97.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2M7YN@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR34280931_k127_778296_20	330214.NIDE1010	5.619e-181	571.0	COG0809@1|root,COG0809@2|Bacteria,3J0HB@40117|Nitrospirae	40117|Nitrospirae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR34280931_k127_778296_14	330214.NIDE1009	3.057e-213	668.0	COG2385@1|root,COG2385@2|Bacteria,3J15K@40117|Nitrospirae	40117|Nitrospirae	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR34280931_k127_778296_51	330214.NIDE1008	7.232e-32	125.0	2DNS1@1|root,32YVX@2|Bacteria,3J1CZ@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR34280931_k127_778296_17	330214.NIDE1007	4.034e-204	640.0	COG0136@1|root,COG0136@2|Bacteria,3J0BR@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR34280931_k127_778296_11	330214.NIDE1006	3.459e-223	695.0	COG3391@1|root,COG3391@2|Bacteria,3J19W@40117|Nitrospirae	2|Bacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,NHL,TIG
SRR34280931_k127_778296_15	330214.NIDE1005	7.131e-211	657.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR34280931_k127_778296_47	330214.NIDE1004	4.341e-64	222.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR34280931_k127_778296_6	330214.NIDE1002	8.187e-320	981.0	COG0119@1|root,COG0119@2|Bacteria,3J0F7@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR34280931_k127_778296_25	330214.NIDE1001	2.514e-154	489.0	COG1183@1|root,COG1183@2|Bacteria,3J0KW@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR34280931_k127_778296_28	330214.NIDE1000	1.323e-128	412.0	COG0688@1|root,COG0688@2|Bacteria,3J0KD@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR34280931_k127_778296_13	330214.NIDE0999	4.308e-215	668.0	COG0059@1|root,COG0059@2|Bacteria,3J0DW@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR34280931_k127_778296_37	330214.NIDE0998	1.056e-99	326.0	COG0440@1|root,COG0440@2|Bacteria,3J0K8@40117|Nitrospirae	40117|Nitrospirae	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR34280931_k127_778296_1	330214.NIDE0997	0.0	1184.0	COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae	40117|Nitrospirae	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR34280931_k127_778296_60	228405.HNE_0478	4.089e-05	51.0	2DEJE@1|root,2ZN82@2|Bacteria,1PB33@1224|Proteobacteria,2UY1B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_778296_24	330214.NIDE0993	7.487e-157	499.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR34280931_k127_778296_33	330214.NIDE0992	1.181e-118	387.0	COG1039@1|root,COG1039@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
SRR34280931_k127_778296_30	330214.NIDE0991	1.542e-123	400.0	COG1579@1|root,COG1579@2|Bacteria,3J0UV@40117|Nitrospirae	40117|Nitrospirae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR34280931_k127_778296_3	330214.NIDE0990	0.0	1122.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR34280931_k127_778296_4	330214.NIDE0989	0.0	1050.0	COG0358@1|root,COG0358@2|Bacteria,3J0IN@40117|Nitrospirae	40117|Nitrospirae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4,Toprim_N,zf-CHC2
SRR34280931_k127_778296_50	661367.LLO_0299	1.21e-41	156.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1JEIC@118969|Legionellales	118969|Legionellales	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR34280931_k127_778296_29	330214.NIDE0987	4.285e-126	405.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,3J0T7@40117|Nitrospirae	40117|Nitrospirae	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR34280931_k127_778296_26	330214.NIDE0986	2.768e-146	467.0	COG0107@1|root,COG0107@2|Bacteria,3J0GV@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR34280931_k127_778296_27	330214.NIDE0985	9.746e-131	420.0	COG0106@1|root,COG0106@2|Bacteria,3J0KA@40117|Nitrospirae	40117|Nitrospirae	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR34280931_k127_778296_32	330214.NIDE0983	1.701e-119	385.0	COG0118@1|root,COG0118@2|Bacteria,3J0K7@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR34280931_k127_778296_31	330214.NIDE0982	1.232e-119	387.0	COG0131@1|root,COG0131@2|Bacteria,3J0JI@40117|Nitrospirae	40117|Nitrospirae	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR34280931_k127_778296_9	330214.NIDE0981	4.242e-250	775.0	COG0141@1|root,COG0141@2|Bacteria,3J0C6@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR34280931_k127_778296_55	330214.NIDE0980	1.843e-16	79.0	COG0040@1|root,COG0040@2|Bacteria,3J0T5@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR34280931_k127_780654_7	671143.DAMO_1955	4.863e-27	113.0	2E5GP@1|root,3308B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_780654_1	671143.DAMO_1956	1.581e-191	605.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_780654_3	671143.DAMO_1957	1.961e-105	349.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_780654_2	671143.DAMO_1958	4.472e-155	496.0	28K4S@1|root,2Z9TM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_780654_5	671143.DAMO_1959	8.277e-63	220.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	NosL
SRR34280931_k127_780654_8	765913.ThidrDRAFT_1395	1.095e-21	101.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1WZ4W@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR34280931_k127_780654_9	671143.DAMO_1948	4.773e-07	57.0	28QX7@1|root,2ZDCB@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_780654_0	671143.DAMO_1960	4.583e-216	679.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K21601	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,NosL
SRR34280931_k127_780654_6	330214.NIDE3879	1.355e-58	209.0	COG2010@1|root,COG2010@2|Bacteria,3J17C@40117|Nitrospirae	40117|Nitrospirae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR34280931_k127_780654_4	330214.NIDE3877	7.953e-85	282.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR34280931_k127_834418_3	330214.NIDE3838	2.727e-15	76.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Usp
SRR34280931_k127_834418_0	620914.JH621254_gene444	2.549e-27	113.0	COG3609@1|root,COG3609@2|Bacteria,4PH6A@976|Bacteroidetes,1IHW1@117743|Flavobacteriia,2YJZY@290174|Aquimarina	976|Bacteroidetes	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	-	-	-	-	-	-	-	-	-	ParD_antitoxin
SRR34280931_k127_834418_2	685035.ADAE01000018_gene993	9.013e-20	91.0	COG3668@1|root,COG3668@2|Bacteria,1N75M@1224|Proteobacteria,2UFHX@28211|Alphaproteobacteria,2K5VP@204457|Sphingomonadales	204457|Sphingomonadales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR34280931_k127_834418_5	330214.NIDE2123	1.157e-10	63.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_29,rve,rve_3
SRR34280931_k127_837588_8	330214.NIDE1657	8.523e-68	246.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	DUF3258,Phage_int_SAM_3,Phage_integrase
SRR34280931_k127_837588_13	330214.NIDE1656	8.186e-29	130.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR34280931_k127_837588_12	330214.NIDE1655	8.488e-32	124.0	28ZVQ@1|root,2ZMK7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_837588_4	330214.NIDE1654	4.476e-114	375.0	COG0345@1|root,COG0345@2|Bacteria,3J0N8@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR34280931_k127_837588_6	330214.NIDE1651	7.953e-85	282.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR34280931_k127_837588_2	330214.NIDE1649	3.857e-181	574.0	2AAUK@1|root,3107C@2|Bacteria,3J1E0@40117|Nitrospirae	40117|Nitrospirae	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR34280931_k127_837588_0	330214.NIDE1648	2.563e-261	811.0	COG3014@1|root,COG3014@2|Bacteria,3J14B@40117|Nitrospirae	40117|Nitrospirae	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
SRR34280931_k127_837588_3	330214.NIDE1647	5.248e-116	376.0	COG3417@1|root,COG3417@2|Bacteria,3J16N@40117|Nitrospirae	40117|Nitrospirae	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
SRR34280931_k127_837588_5	330214.NIDE1646	5.564e-109	356.0	2EUFJ@1|root,33MXU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR34280931_k127_837588_1	330214.NIDE1644	3.399e-234	731.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
SRR34280931_k127_837588_9	330214.NIDE1643	9.468e-68	232.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR34280931_k127_85320_66	330214.NIDE1088	1.443e-39	147.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR34280931_k127_85320_33	330214.NIDE1089	1.488e-126	411.0	COG1040@1|root,COG1040@2|Bacteria,3J19P@40117|Nitrospirae	40117|Nitrospirae	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR34280931_k127_85320_36	330214.NIDE1090	1.901e-121	394.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_85320_24	330214.NIDE1091	9.094e-176	554.0	COG0167@1|root,COG0167@2|Bacteria,3J145@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR34280931_k127_85320_61	330214.NIDE1093	1.194e-51	184.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	AroM,GerE
SRR34280931_k127_85320_3	330214.NIDE1094	0.0	1313.0	COG0577@1|root,COG0577@2|Bacteria,3J0Z3@40117|Nitrospirae	40117|Nitrospirae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_85320_39	1382306.JNIM01000001_gene3109	2.034e-119	393.0	COG0502@1|root,COG0502@2|Bacteria	2|Bacteria	H	biotin synthase activity	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30200	BATS,Radical_SAM
SRR34280931_k127_85320_8	330214.NIDE1096	2.236e-293	902.0	COG2956@1|root,COG2956@2|Bacteria,3J0KC@40117|Nitrospirae	40117|Nitrospirae	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR34280931_k127_85320_72	644282.Deba_2405	1.045e-24	110.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR34280931_k127_85320_44	330214.NIDE1098	1.507e-109	357.0	COG1057@1|root,COG1057@2|Bacteria,3J0T3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR34280931_k127_85320_17	330214.NIDE1099	4.837e-214	671.0	COG0263@1|root,COG0263@2|Bacteria,3J0GU@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR34280931_k127_85320_35	1123376.AUIU01000016_gene303	1.349e-123	405.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR34280931_k127_85320_63	330214.NIDE1101	1.111e-49	177.0	COG0211@1|root,COG0211@2|Bacteria,3J0RB@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR34280931_k127_85320_62	330214.NIDE1102	4.397e-51	187.0	COG0261@1|root,COG0261@2|Bacteria,3J0TM@40117|Nitrospirae	40117|Nitrospirae	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR34280931_k127_85320_21	330214.NIDE1103	5.62e-193	603.0	COG0115@1|root,COG0115@2|Bacteria,3J0BM@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR34280931_k127_85320_59	330214.NIDE1104	1.506e-56	198.0	COG1314@1|root,COG1314@2|Bacteria,3J0V0@40117|Nitrospirae	40117|Nitrospirae	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR34280931_k127_85320_30	330214.NIDE1105	3.687e-138	442.0	COG0149@1|root,COG0149@2|Bacteria,3J0MW@40117|Nitrospirae	40117|Nitrospirae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR34280931_k127_85320_14	330214.NIDE1106	1.061e-251	777.0	COG0126@1|root,COG0126@2|Bacteria,3J0DE@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR34280931_k127_85320_18	330214.NIDE1107	2.782e-210	654.0	COG0057@1|root,COG0057@2|Bacteria,3J0D8@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR34280931_k127_85320_2	330214.NIDE1108	0.0	1321.0	COG1193@1|root,COG1193@2|Bacteria,3J0Y0@40117|Nitrospirae	40117|Nitrospirae	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR34280931_k127_85320_6	330214.NIDE1109	0.0	1076.0	COG0642@1|root,COG2205@2|Bacteria	330214.NIDE1109|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_85320_68	1306406.ASHX01000001_gene2449	9.234e-34	140.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR34280931_k127_85320_43	330214.NIDE1114	1.425e-112	370.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,NB-ARC,PG_binding_1,TPR_10,TniB
SRR34280931_k127_85320_9	330214.NIDE1115	6.27e-284	880.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Trypsin_2
SRR34280931_k127_85320_4	330214.NIDE1116	0.0	1213.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,3J0XC@40117|Nitrospirae	40117|Nitrospirae	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR34280931_k127_85320_50	330214.NIDE1117	3.073e-84	281.0	2EKQ4@1|root,33EDV@2|Bacteria	2|Bacteria	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR34280931_k127_85320_27	330214.NIDE1118	9.465e-159	504.0	COG4783@1|root,COG4783@2|Bacteria,3J193@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR34280931_k127_85320_7	330214.NIDE1119	1.12e-303	941.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1,dCache_2
SRR34280931_k127_85320_12	330214.NIDE1120	1.179e-265	823.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_85320_26	330214.NIDE1121	3.655e-173	548.0	COG1600@1|root,COG1600@2|Bacteria,3J19A@40117|Nitrospirae	40117|Nitrospirae	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR34280931_k127_85320_42	330214.NIDE1123	8.26e-113	369.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE1123|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_85320_15	330214.NIDE1125	1.425e-226	704.0	COG0301@1|root,COG0301@2|Bacteria	2|Bacteria	H	tRNA thio-modification	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
SRR34280931_k127_85320_70	717231.Flexsi_1740	1.644e-31	126.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR34280931_k127_85320_25	330214.NIDE1127	2.279e-174	549.0	COG0492@1|root,COG0492@2|Bacteria,3J0M0@40117|Nitrospirae	40117|Nitrospirae	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR34280931_k127_85320_46	330214.NIDE1128	1.398e-89	304.0	COG0237@1|root,COG0237@2|Bacteria,3J0RK@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR34280931_k127_85320_23	330214.NIDE1129	1.038e-184	581.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3
SRR34280931_k127_85320_0	330214.NIDE1131	0.0	1724.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SRR34280931_k127_85320_5	330214.NIDE1132	0.0	1126.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR34280931_k127_85320_51	330214.NIDE1136	1.998e-83	281.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	hbpS	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
SRR34280931_k127_85320_28	330214.NIDE1138	6.404e-155	497.0	COG2084@1|root,COG2084@2|Bacteria,3J0YI@40117|Nitrospirae	40117|Nitrospirae	C	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR34280931_k127_85320_64	330214.NIDE1139	1.092e-43	161.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,DUF3565
SRR34280931_k127_85320_19	330214.NIDE1142	9.08e-200	626.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR34280931_k127_85320_31	330214.NIDE1143	1.026e-137	440.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR34280931_k127_85320_41	330214.NIDE1145	3.353e-116	381.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
SRR34280931_k127_85320_10	330214.NIDE1146	5.232e-279	864.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR34280931_k127_85320_40	330214.NIDE1147	3.155e-117	381.0	292MF@1|root,2ZQ5C@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
SRR34280931_k127_85320_69	1121335.Clst_0122	2.086e-32	140.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM
SRR34280931_k127_85320_65	237368.SCABRO_01823	7.305e-40	158.0	COG0398@1|root,COG0398@2|Bacteria,2J4Y1@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
SRR34280931_k127_85320_53	472759.Nhal_2124	3.334e-78	271.0	COG1215@1|root,COG1215@2|Bacteria,1QU2M@1224|Proteobacteria,1SCHV@1236|Gammaproteobacteria,1X2RE@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_85320_58	330214.NIDE1149	5.739e-57	200.0	2EIBB@1|root,33C2R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_85320_1	330214.NIDE1150	0.0	1466.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,3J0NX@40117|Nitrospirae	40117|Nitrospirae	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
SRR34280931_k127_85320_29	330214.NIDE1152	7.47e-146	467.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	3.5.1.54,6.3.4.6	ko:K01457,ko:K01941,ko:K06350	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005,R00774	RC00378,RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D
SRR34280931_k127_85320_56	1329516.JPST01000025_gene2175	5.611e-64	235.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,27AW2@186824|Thermoactinomycetaceae	91061|Bacilli	S	LamB/YcsF family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR34280931_k127_85320_45	330214.NIDE1154	5.133e-91	304.0	COG2049@1|root,COG2049@2|Bacteria	2|Bacteria	E	5-oxoprolinase (ATP-hydrolyzing) activity	kipI	-	3.5.1.54	ko:K01457,ko:K06351,ko:K07160	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_C_D
SRR34280931_k127_85320_13	330214.NIDE1155	8.893e-252	780.0	COG0477@1|root,COG2814@2|Bacteria,3J171@40117|Nitrospirae	40117|Nitrospirae	EGP	Sugar (and other) transporter	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	MFS_1
SRR34280931_k127_85320_38	330214.NIDE1156	1.744e-120	389.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR34280931_k127_85320_16	330214.NIDE1157	1.311e-219	686.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR34280931_k127_85320_37	330214.NIDE1159	4.275e-121	393.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4041,GGDEF,HATPase_c,HisKA,Response_reg,T5orf172,dCache_1
SRR34280931_k127_85320_20	330214.NIDE1160	8.868e-197	620.0	COG0075@1|root,COG0075@2|Bacteria,3J0FC@40117|Nitrospirae	2|Bacteria	E	Evidence 2b Function of strongly homologous gene	spt	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR34280931_k127_85320_11	330214.NIDE1161	3.657e-270	839.0	COG1266@1|root,COG1633@1|root,COG1266@2|Bacteria,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594,ko:K07052	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Abi
SRR34280931_k127_85320_49	330214.NIDE3333	2.98e-86	291.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,3J0VE@40117|Nitrospirae	40117|Nitrospirae	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR34280931_k127_85320_74	1430440.MGMSRv2_3438	3.067e-07	63.0	2DM57@1|root,31S0Y@2|Bacteria,1R3A8@1224|Proteobacteria,2TZZU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_85320_34	330214.NIDE1162	3.035e-125	407.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10
SRR34280931_k127_85320_22	330214.NIDE1163	5.937e-187	589.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
SRR34280931_k127_85320_32	330214.NIDE1164	3.134e-127	408.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_862555_1	522772.Dacet_0624	4.827e-33	130.0	COG2963@1|root,COG2963@2|Bacteria,2GGNA@200930|Deferribacteres	200930|Deferribacteres	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_862555_0	1266925.JHVX01000002_gene795	6.137e-104	347.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,372VZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
SRR34280931_k127_862990_22	330214.NIDE1042	9.37e-104	339.0	COG4122@1|root,COG4122@2|Bacteria,3J1C3@40117|Nitrospirae	40117|Nitrospirae	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_862990_14	330214.NIDE1043	7.647e-160	507.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yetK	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR34280931_k127_862990_10	330214.NIDE0936	8.006e-176	567.0	COG4585@1|root,COG4585@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
SRR34280931_k127_862990_20	330214.NIDE0935	6.35e-109	355.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR34280931_k127_862990_13	330214.NIDE1044	1.129e-161	517.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR34280931_k127_862990_37	246969.TAM4_2433	7.752e-36	153.0	COG0463@1|root,arCOG01381@2157|Archaea,2XVM0@28890|Euryarchaeota,243JM@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_862990_28	1173026.Glo7428_1317	2.997e-72	255.0	COG1216@1|root,COG1216@2|Bacteria,1G5HZ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_862990_38	1121346.KB899819_gene2423	8.363e-32	134.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HCJW@91061|Bacilli,26QKG@186822|Paenibacillaceae	91061|Bacilli	G	deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRR34280931_k127_862990_15	330214.NIDE1045	1.348e-147	474.0	28JAC@1|root,2Z956@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_862990_21	330214.NIDE0507	1.749e-106	355.0	COG1682@1|root,COG1682@2|Bacteria,3J1DI@40117|Nitrospirae	2|Bacteria	U	ABC-2 type transporter	wzm	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR34280931_k127_862990_16	330214.NIDE0508	2.728e-138	451.0	COG1134@1|root,COG1134@2|Bacteria,3J142@40117|Nitrospirae	2|Bacteria	GM	Evidence 2b Function of strongly homologous gene	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_862990_0	330214.NIDE1046	0.0	2120.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	barA	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR34280931_k127_862990_4	330214.NIDE1047	3.353e-268	829.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K02584,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_862990_34	330214.NIDE1051	9.522e-43	158.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Phosphonate-bd
SRR34280931_k127_862990_26	330214.NIDE1052	2.587e-83	276.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR34280931_k127_862990_31	330214.NIDE1053	2.218e-50	183.0	2FBTK@1|root,343YA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_862990_39	330214.NIDE1055	8.748e-30	121.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Phosphonate-bd
SRR34280931_k127_862990_9	330214.NIDE1059	4.998e-205	641.0	COG0404@1|root,COG0404@2|Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	1.5.99.5,2.1.2.10	ko:K00605,ko:K06980,ko:K22086	ko00260,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200	M00532	R00609,R01221,R02300,R04125	RC00022,RC00069,RC00183,RC00190,RC00557,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR34280931_k127_862990_30	330214.NIDE1060	1.293e-59	208.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR34280931_k127_862990_19	330214.NIDE1061	3.478e-110	357.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR34280931_k127_862990_11	330214.NIDE1062	5.229e-169	532.0	COG1635@1|root,COG1635@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	FAD_oxidored,Thi4
SRR34280931_k127_862990_3	330214.NIDE1063	0.0	1255.0	COG0422@1|root,COG0422@2|Bacteria,3J0AY@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
SRR34280931_k127_862990_43	1223521.BBJX01000002_gene2670	3.13e-08	62.0	29DIQ@1|root,300GG@2|Bacteria,1RJVY@1224|Proteobacteria,2VTHH@28216|Betaproteobacteria,4AEF9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
SRR34280931_k127_862990_25	330214.NIDE2812	4.407e-88	297.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4041,GGDEF,HATPase_c,HisKA,Response_reg,T5orf172,dCache_1
SRR34280931_k127_862990_2	330214.NIDE1067	0.0	1451.0	2DBJW@1|root,2Z9P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_862990_42	330214.NIDE2812	2.265e-11	64.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4041,GGDEF,HATPase_c,HisKA,Response_reg,T5orf172,dCache_1
SRR34280931_k127_862990_40	945713.IALB_1353	1.62e-13	73.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria	2|Bacteria	U	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262,HNH
SRR34280931_k127_862990_41	234267.Acid_6411	1.239e-12	70.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR34280931_k127_862990_5	330214.NIDE1076	4.494e-241	746.0	COG0379@1|root,COG0379@2|Bacteria,3J0NV@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR34280931_k127_862990_1	330214.NIDE1077	0.0	1821.0	COG0060@1|root,COG0060@2|Bacteria,3J0BF@40117|Nitrospirae	40117|Nitrospirae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR34280931_k127_862990_24	330214.NIDE1078	1.967e-88	300.0	COG0597@1|root,COG0597@2|Bacteria,3J0S2@40117|Nitrospirae	40117|Nitrospirae	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR34280931_k127_862990_12	330214.NIDE1080	1.86e-164	520.0	COG1968@1|root,COG1968@2|Bacteria,3J0S7@40117|Nitrospirae	40117|Nitrospirae	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR34280931_k127_862990_18	330214.NIDE1081	2.974e-110	362.0	COG1196@1|root,COG1555@1|root,COG1196@2|Bacteria,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR34280931_k127_862990_8	330214.NIDE1082	1.264e-210	661.0	COG0845@1|root,COG0845@2|Bacteria,3J0HQ@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR34280931_k127_862990_17	330214.NIDE1083	3.22e-135	432.0	COG1136@1|root,COG1136@2|Bacteria,3J10N@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR34280931_k127_862990_6	330214.NIDE1084	9.139e-234	730.0	COG0577@1|root,COG0577@2|Bacteria,3J0EW@40117|Nitrospirae	40117|Nitrospirae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR34280931_k127_862990_7	330214.NIDE1085	4.073e-220	687.0	COG2206@1|root,COG2206@2|Bacteria,3J14V@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
SRR34280931_k127_862990_29	330214.NIDE1086	1.781e-65	230.0	COG4570@1|root,COG4570@2|Bacteria	2|Bacteria	L	crossover junction endodeoxyribonuclease activity	rusA	-	3.1.22.4	ko:K01160	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	RusA
SRR34280931_k127_862990_27	330214.NIDE1087	2.862e-82	275.0	COG2001@1|root,COG2001@2|Bacteria,3J0VQ@40117|Nitrospirae	40117|Nitrospirae	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR34280931_k127_865472_1	330214.NIDE2291	1.688e-270	834.0	COG1157@1|root,COG1157@2|Bacteria,3J0BV@40117|Nitrospirae	40117|Nitrospirae	N	ATP synthase alpha/beta family, beta-barrel domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR34280931_k127_865472_16	330214.NIDE2293	2.359e-71	247.0	COG3334@1|root,COG3334@2|Bacteria	2|Bacteria	S	PFAM MgtE intracellular	ylxF	-	-	ko:K02383	-	-	-	-	ko00000,ko02035	-	-	-	MgtE_N
SRR34280931_k127_865472_20	330214.NIDE2296	2.696e-45	165.0	COG1843@1|root,COG1843@2|Bacteria,3J0U1@40117|Nitrospirae	40117|Nitrospirae	N	flagellar hook	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
SRR34280931_k127_865472_3	330214.NIDE2297	8.032e-232	721.0	COG1749@1|root,COG1749@2|Bacteria,3J0IF@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar basal body protein FlaE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
SRR34280931_k127_865472_14	330214.NIDE2298	1.143e-81	288.0	COG1580@1|root,COG1580@2|Bacteria,3J0QH@40117|Nitrospirae	40117|Nitrospirae	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
SRR34280931_k127_865472_5	330214.NIDE2299	4.099e-201	631.0	COG1868@1|root,COG1868@2|Bacteria,3J0CU@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
SRR34280931_k127_865472_18	330214.NIDE2300	4.529e-59	208.0	COG1886@1|root,COG1886@2|Bacteria,3J0QM@40117|Nitrospirae	40117|Nitrospirae	N	Type III flagellar switch regulator (C-ring) FliN C-term	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
SRR34280931_k127_865472_25	330214.NIDE2301	1.691e-36	144.0	COG3190@1|root,COG3190@2|Bacteria	2|Bacteria	N	flagellar	fliP	-	-	ko:K02418,ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO,FliP
SRR34280931_k127_865472_12	330214.NIDE2302	5.502e-125	406.0	COG1338@1|root,COG1338@2|Bacteria,3J0HW@40117|Nitrospirae	40117|Nitrospirae	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO,FliP
SRR34280931_k127_865472_21	330214.NIDE2303	3.586e-41	158.0	COG1987@1|root,COG1987@2|Bacteria,3J0VH@40117|Nitrospirae	40117|Nitrospirae	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
SRR34280931_k127_865472_24	177439.DP2673	5.091e-39	155.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WNFE@28221|Deltaproteobacteria,2MPY8@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Bacterial export proteins, family 1	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
SRR34280931_k127_865472_6	330214.NIDE2305	2.747e-198	621.0	COG1377@1|root,COG1377@2|Bacteria,3J0J3@40117|Nitrospirae	40117|Nitrospirae	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
SRR34280931_k127_865472_0	330214.NIDE2306	0.0	1257.0	COG1298@1|root,COG1298@2|Bacteria,3J0B1@40117|Nitrospirae	40117|Nitrospirae	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRR34280931_k127_865472_4	330214.NIDE2307	4.673e-220	688.0	COG1419@1|root,COG1419@2|Bacteria,3J162@40117|Nitrospirae	40117|Nitrospirae	N	SRP54-type protein, GTPase domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
SRR34280931_k127_865472_7	330214.NIDE2308	1.512e-162	514.0	COG0455@1|root,COG0455@2|Bacteria,3J0JR@40117|Nitrospirae	40117|Nitrospirae	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31
SRR34280931_k127_865472_9	330214.NIDE2309	9.047e-147	466.0	COG1191@1|root,COG1191@2|Bacteria,3J0NW@40117|Nitrospirae	40117|Nitrospirae	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR34280931_k127_865472_13	330214.NIDE2310	9.307e-86	292.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_4,PAS_9,Response_reg
SRR34280931_k127_865472_10	330214.NIDE2311	1.49e-138	443.0	COG4786@1|root,COG4786@2|Bacteria,3J16I@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR34280931_k127_865472_8	330214.NIDE2312	4.456e-162	511.0	COG4786@1|root,COG4786@2|Bacteria,3J0IQ@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR34280931_k127_865472_11	330214.NIDE2313	4.687e-133	428.0	COG1261@1|root,COG1261@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgA	-	-	ko:K02279,ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	ChapFlgA
SRR34280931_k127_865472_23	398767.Glov_3279	3.352e-40	158.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WMYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
SRR34280931_k127_865472_2	330214.NIDE2315	2.375e-244	762.0	COG1706@1|root,COG1706@2|Bacteria,3J0MB@40117|Nitrospirae	40117|Nitrospirae	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
SRR34280931_k127_865472_22	330214.NIDE2316	2.843e-40	153.0	COG3951@1|root,COG3951@2|Bacteria	2|Bacteria	MNO	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02035	-	GH23	-	Rod-binding
SRR34280931_k127_865472_19	330214.NIDE2317	5.824e-50	179.0	COG2747@1|root,COG2747@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgM	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
SRR34280931_k127_886373_23	1123053.AUDG01000006_gene3846	3.366e-29	127.0	COG0299@1|root,COG0299@2|Bacteria,1NIYA@1224|Proteobacteria,1SIJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR34280931_k127_886373_19	402881.Plav_3318	1.826e-40	165.0	COG4106@1|root,COG4106@2|Bacteria,1R02P@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR34280931_k127_886373_20	1121481.AUAS01000003_gene4103	1.051e-38	158.0	COG5285@1|root,COG5285@2|Bacteria,4NK9U@976|Bacteroidetes,47MVP@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR34280931_k127_886373_0	103690.17129901	3.841e-180	573.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1HR4E@1161|Nostocales	1117|Cyanobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR34280931_k127_886373_1	373994.Riv7116_5626	8.743e-165	531.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1HN29@1161|Nostocales	1117|Cyanobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR34280931_k127_886373_4	344747.PM8797T_19979	5.554e-150	490.0	COG3356@1|root,COG3356@2|Bacteria,2J2EY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_886373_8	1382306.JNIM01000001_gene1105	3.543e-116	396.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	200795|Chloroflexi	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRR34280931_k127_886373_21	269799.Gmet_2336	9.081e-34	141.0	COG0463@1|root,COG0463@2|Bacteria,1RKGW@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_886373_7	1283300.ATXB01000001_gene1379	9.122e-125	410.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XFHT@135618|Methylococcales	135618|Methylococcales	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR34280931_k127_886373_11	1121441.AUCX01000016_gene2328	4.747e-84	289.0	COG1052@1|root,COG1052@2|Bacteria,1QVZS@1224|Proteobacteria,43A0B@68525|delta/epsilon subdivisions,2X1TR@28221|Deltaproteobacteria,2MC2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR34280931_k127_886373_3	1121904.ARBP01000005_gene4705	4.382e-158	507.0	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,47NJS@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
SRR34280931_k127_886373_15	1385512.N784_05290	5.105e-52	194.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,4HG7P@91061|Bacilli	91061|Bacilli	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR34280931_k127_886373_2	1123234.AUKI01000015_gene2296	1.601e-163	533.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR34280931_k127_886373_14	349520.PPE_02490	7.941e-53	196.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,26QGX@186822|Paenibacillaceae	91061|Bacilli	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR34280931_k127_886373_27	1206101.AZXC01000030_gene1912	1.268e-06	60.0	COG2334@1|root,COG2334@2|Bacteria,2GNSC@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
SRR34280931_k127_886373_18	1382356.JQMP01000004_gene175	8.119e-41	162.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27YS7@189775|Thermomicrobia	189775|Thermomicrobia	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR34280931_k127_886373_9	234267.Acid_2241	8.52e-107	357.0	COG0673@1|root,COG0673@2|Bacteria,3Y754@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR34280931_k127_886373_25	317013.NY99_10700	4.126e-14	83.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR34280931_k127_886373_12	1499967.BAYZ01000086_gene5159	6.914e-67	236.0	COG1083@1|root,COG1083@2|Bacteria,2NQYB@2323|unclassified Bacteria	2|Bacteria	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR34280931_k127_886373_13	720554.Clocl_0400	6.332e-58	207.0	COG0110@1|root,COG0110@2|Bacteria,1V2DC@1239|Firmicutes,24GM5@186801|Clostridia,3WIM1@541000|Ruminococcaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRR34280931_k127_886373_6	234267.Acid_2246	3.07e-130	423.0	COG2089@1|root,COG2089@2|Bacteria,3Y39R@57723|Acidobacteria	57723|Acidobacteria	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR34280931_k127_886373_10	234267.Acid_2240	1.177e-105	350.0	COG1028@1|root,COG1028@2|Bacteria,3Y3U1@57723|Acidobacteria	57723|Acidobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR34280931_k127_886373_16	357808.RoseRS_2381	2.933e-51	196.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,375VE@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR34280931_k127_886373_24	926569.ANT_06410	1.939e-26	125.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
SRR34280931_k127_886373_26	866895.HBHAL_1436	1.093e-07	64.0	COG0438@1|root,COG0438@2|Bacteria,1V0JQ@1239|Firmicutes,4HE9R@91061|Bacilli,3ND62@45667|Halobacillus	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_886373_22	1144313.PMI10_01280	2.101e-29	126.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes,1IIUR@117743|Flavobacteriia,2P0G9@237|Flavobacterium	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR34280931_k127_886373_5	518766.Rmar_1136	1.377e-149	477.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes	976|Bacteroidetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_892519_11	330214.NIDE3518	3.533e-111	366.0	COG1651@1|root,COG1651@2|Bacteria,3J19Z@40117|Nitrospirae	40117|Nitrospirae	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_892519_0	330214.NIDE3519	0.0	3276.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR34280931_k127_892519_9	138119.DSY0252	6.021e-120	400.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR34280931_k127_892519_4	330214.NIDE3521	0.0	1230.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HDOD,HisKA,Response_reg
SRR34280931_k127_892519_8	330214.NIDE3522	1.701e-124	403.0	COG3182@1|root,COG3182@2|Bacteria	2|Bacteria	E	Iron-regulated membrane protein	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM,PepSY_TM_like_2
SRR34280931_k127_892519_7	330214.NIDE3523	4.361e-131	428.0	COG5266@1|root,COG5266@2|Bacteria	2|Bacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
SRR34280931_k127_892519_3	330214.NIDE3524	0.0	1268.0	COG4772@1|root,COG4772@2|Bacteria	330214.NIDE3524|-	P	TonB-dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	-
SRR34280931_k127_892519_22	448385.sce3887	0.0002309	48.0	2BR48@1|root,32K27@2|Bacteria,1Q2KM@1224|Proteobacteria,43878@68525|delta/epsilon subdivisions,2X3H6@28221|Deltaproteobacteria,2YW2M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_892519_18	330214.NIDE2189	9.839e-30	131.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SRR34280931_k127_892519_1	330214.NIDE3527	0.0	1819.0	COG0841@1|root,COG0841@2|Bacteria,3J0XV@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
SRR34280931_k127_892519_2	330214.NIDE3528	0.0	1810.0	COG0841@1|root,COG0841@2|Bacteria,3J0XV@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
SRR34280931_k127_892519_5	330214.NIDE3529	3.5e-228	714.0	COG0845@1|root,COG0845@2|Bacteria,3J11U@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	-
SRR34280931_k127_892519_21	641491.DND132_1533	1.096e-05	50.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,42SGS@68525|delta/epsilon subdivisions,2WPQ9@28221|Deltaproteobacteria,2MB1H@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR34280931_k127_892519_6	330214.NIDE3531	1.08e-152	486.0	COG0583@1|root,COG0583@2|Bacteria,3J16P@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulator	-	-	-	ko:K11921,ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR34280931_k127_892519_10	330214.NIDE3533	2.684e-113	370.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	yiiM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0098754	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR34280931_k127_892519_13	330214.NIDE3536	1.46e-77	262.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PIG-L,Response_reg
SRR34280931_k127_892519_17	1521187.JPIM01000013_gene2727	2.757e-32	132.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_897460_4	279238.Saro_0618	1.102e-05	49.0	2ANH5@1|root,31DFW@2|Bacteria,1P4RK@1224|Proteobacteria,2UWSD@28211|Alphaproteobacteria,2KC8C@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_897460_0	279238.Saro_0617	1.149e-85	297.0	COG0582@1|root,COG0582@2|Bacteria,1R7GV@1224|Proteobacteria,2TT06@28211|Alphaproteobacteria,2K9X5@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_897460_3	391619.PGA1_c30860	1.109e-12	73.0	2C2GW@1|root,2ZFK3@2|Bacteria,1PA8Y@1224|Proteobacteria,2UXK3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_902571_4	247490.KSU1_D0848	9.064e-31	121.0	COG0842@1|root,COG0842@2|Bacteria,2IYZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR34280931_k127_902571_1	330214.NIDE3910	7.354e-108	357.0	COG3170@1|root,COG3170@2|Bacteria,3J1CW@40117|Nitrospirae	40117|Nitrospirae	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
SRR34280931_k127_902571_2	330214.NIDE3923	8.022e-66	228.0	2ED3M@1|root,3370H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
SRR34280931_k127_902571_0	330214.NIDE3921	4.542e-128	422.0	29TFP@1|root,30ENV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRR34280931_k127_902571_3	330214.NIDE3914	3.098e-65	223.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR34280931_k127_909735_22	330214.NIDE3038	6.171e-55	194.0	COG0673@1|root,COG0673@2|Bacteria,3J0M7@40117|Nitrospirae	40117|Nitrospirae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR34280931_k127_909735_3	330214.NIDE3037	1.701e-226	704.0	COG0763@1|root,COG0763@2|Bacteria,3J0MA@40117|Nitrospirae	40117|Nitrospirae	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR34280931_k127_909735_1	330214.NIDE3036	0.0	1042.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR34280931_k127_909735_18	330214.NIDE3035	4.711e-104	342.0	COG2121@1|root,COG2121@2|Bacteria,3J1AI@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR34280931_k127_909735_4	330214.NIDE3033	2.717e-221	694.0	COG1519@1|root,COG1519@2|Bacteria,3J0J7@40117|Nitrospirae	40117|Nitrospirae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR34280931_k127_909735_20	404380.Gbem_0848	1.544e-70	253.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR34280931_k127_909735_2	330214.NIDE3031	1.404e-319	985.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,3J0PZ@40117|Nitrospirae	40117|Nitrospirae	EM	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SRR34280931_k127_909735_11	330214.NIDE3030	7.433e-177	559.0	COG0859@1|root,COG0859@2|Bacteria,3J0KI@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR34280931_k127_909735_7	330214.NIDE3029	7.902e-203	640.0	COG0438@1|root,COG0438@2|Bacteria,3J129@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_909735_0	330214.NIDE3028	0.0	1203.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	ltaS2	-	2.7.8.20	ko:K01002,ko:K01138	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
SRR34280931_k127_909735_14	330214.NIDE3027	8.106e-163	513.0	COG0463@1|root,COG0463@2|Bacteria,3J0M5@40117|Nitrospirae	40117|Nitrospirae	M	biosynthesis glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_909735_17	330214.NIDE3026	1.988e-146	466.0	COG0463@1|root,COG0463@2|Bacteria,3J0M5@40117|Nitrospirae	40117|Nitrospirae	M	biosynthesis glycosyltransferase	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
SRR34280931_k127_909735_8	330214.NIDE3025	1.194e-189	597.0	COG0438@1|root,COG0438@2|Bacteria,3J19R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_909735_12	330214.NIDE3023	2.287e-176	557.0	COG0859@1|root,COG0859@2|Bacteria,3J161@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR34280931_k127_909735_13	330214.NIDE3022	1.405e-168	533.0	COG1216@1|root,COG1216@2|Bacteria,3J1DN@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_909735_15	330214.NIDE3020	7.651e-162	512.0	COG1216@1|root,COG1216@2|Bacteria,3J1DN@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR34280931_k127_909735_10	330214.NIDE3019	1.018e-181	574.0	COG0438@1|root,COG0438@2|Bacteria,3J19R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR34280931_k127_909735_16	330214.NIDE3016	3.109e-154	488.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR34280931_k127_909735_5	330214.NIDE3015	1.126e-215	670.0	COG1088@1|root,COG1088@2|Bacteria,3J0CT@40117|Nitrospirae	40117|Nitrospirae	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR34280931_k127_909735_21	1121346.KB899817_gene3225	8.195e-66	235.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR34280931_k127_909735_9	330214.NIDE3013	3.743e-187	594.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K02849,ko:K21003	ko00540,ko01100,ko02025,map00540,map01100,map02025	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	9.B.67.4,9.B.67.5	GT9	-	Glyco_transf_25,Wzy_C
SRR34280931_k127_909735_6	330214.NIDE3012	6.384e-214	664.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR34280931_k127_909735_19	330214.NIDE3011	1.947e-87	290.0	COG0451@1|root,COG0451@2|Bacteria,3J0XH@40117|Nitrospirae	40117|Nitrospirae	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR34280931_k127_91564_13	330214.NIDE0952	1.977e-159	507.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K07012	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000,ko02048	-	-	-	HD
SRR34280931_k127_91564_22	330214.NIDE0953	1.072e-69	237.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR34280931_k127_91564_9	330214.NIDE0954	2.237e-194	610.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	degP	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
SRR34280931_k127_91564_2	330214.NIDE0955	0.0	1066.0	COG1222@1|root,COG1222@2|Bacteria,3J0Z7@40117|Nitrospirae	40117|Nitrospirae	O	Proteasomal ATPase OB/ID domain	-	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR34280931_k127_91564_3	330214.NIDE0956	2.446e-312	959.0	COG4122@1|root,COG4122@2|Bacteria,3J0ZW@40117|Nitrospirae	40117|Nitrospirae	S	Pup-ligase protein	-	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR34280931_k127_91564_28	330214.NIDE0957	7.774e-30	119.0	2ERDX@1|root,33IZH@2|Bacteria	2|Bacteria	S	May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes	ubact	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_91564_14	330214.NIDE0958	6.637e-151	479.0	COG0638@1|root,COG0638@2|Bacteria,3J11F@40117|Nitrospirae	40117|Nitrospirae	O	Proteasome subunit	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR34280931_k127_91564_16	330214.NIDE0959	3.119e-139	446.0	COG0638@1|root,COG0638@2|Bacteria,3J15S@40117|Nitrospirae	40117|Nitrospirae	O	Proteasome subunit	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR34280931_k127_91564_4	330214.NIDE0960	3.828e-310	953.0	COG4122@1|root,COG4122@2|Bacteria,3J0XW@40117|Nitrospirae	40117|Nitrospirae	S	Pup-ligase protein	-	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR34280931_k127_91564_1	330214.NIDE0963	0.0	1340.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_4,Abhydrolase_6,Hydrolase_4,Methyltransf_11
SRR34280931_k127_91564_0	330214.NIDE0964	0.0	1862.0	COG0642@1|root,COG2205@2|Bacteria	330214.NIDE0964|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_91564_12	330214.NIDE0965	1.065e-171	545.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	-	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR34280931_k127_91564_18	330214.NIDE0966	3.637e-127	407.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	fucA	-	2.2.1.8,4.1.2.17	ko:K01628,ko:K18847	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR34280931_k127_91564_24	330214.NIDE0968	8.043e-54	190.0	COG1144@1|root,COG1144@2|Bacteria,3J1DG@40117|Nitrospirae	40117|Nitrospirae	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_91564_15	330214.NIDE0969	3.657e-142	454.0	COG1014@1|root,COG1014@2|Bacteria,3J0Y6@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SRR34280931_k127_91564_10	330214.NIDE0970	1.593e-193	604.0	COG1013@1|root,COG1013@2|Bacteria,3J0Z2@40117|Nitrospirae	40117|Nitrospirae	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR34280931_k127_91564_6	330214.NIDE0971	1.481e-271	835.0	COG0674@1|root,COG0674@2|Bacteria,3J0WN@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR34280931_k127_91564_17	330214.NIDE0972	1.188e-138	441.0	COG0226@1|root,COG0226@2|Bacteria,3J0YH@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	-	-	-	-	-	-	-	-	-	CO_dh
SRR34280931_k127_91564_29	247634.GPB2148_3705	5.22e-15	78.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1J6PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
SRR34280931_k127_91564_21	330214.NIDE0974	4.62e-76	257.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR34280931_k127_91564_5	330214.NIDE0975	3.039e-273	841.0	COG1158@1|root,COG1158@2|Bacteria,3J0BK@40117|Nitrospirae	40117|Nitrospirae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR34280931_k127_91564_27	330214.NIDE0976	4.437e-40	148.0	COG0254@1|root,COG0254@2|Bacteria,3J0S4@40117|Nitrospirae	40117|Nitrospirae	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR34280931_k127_91564_8	330214.NIDE0977	3.275e-215	670.0	COG0216@1|root,COG0216@2|Bacteria,3J0F6@40117|Nitrospirae	40117|Nitrospirae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR34280931_k127_91564_19	330214.NIDE0978	2.395e-124	406.0	COG2890@1|root,COG2890@2|Bacteria,3J0N5@40117|Nitrospirae	40117|Nitrospirae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR34280931_k127_91564_7	330214.NIDE0979	1.215e-241	750.0	COG0766@1|root,COG0766@2|Bacteria,3J0EE@40117|Nitrospirae	40117|Nitrospirae	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR34280931_k127_91564_20	330214.NIDE0980	6.064e-104	340.0	COG0040@1|root,COG0040@2|Bacteria,3J0T5@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR34280931_k127_942083_1	330214.NIDE1289	1.875e-248	768.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR34280931_k127_942083_0	330214.NIDE1291	0.0	1300.0	COG0210@1|root,COG0210@2|Bacteria,3J0VX@40117|Nitrospirae	40117|Nitrospirae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR34280931_k127_942083_4	1122971.BAME01000045_gene3896	8.369e-05	49.0	293V0@1|root,2ZRA7@2|Bacteria,4P8QC@976|Bacteroidetes,2FVS2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR34280931_k127_961302_2	330214.NIDE2714	7.608e-75	252.0	COG0250@1|root,COG0250@2|Bacteria,3J17S@40117|Nitrospirae	40117|Nitrospirae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
SRR34280931_k127_961302_9	398720.MED217_15110	2.423e-08	58.0	COG2963@1|root,COG2963@2|Bacteria,4NSUA@976|Bacteroidetes,1I443@117743|Flavobacteriia,2XJPC@283735|Leeuwenhoekiella	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR34280931_k127_961302_4	330214.NIDE2899	8.668e-68	239.0	COG1596@1|root,COG1596@2|Bacteria,3J17R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR34280931_k127_961302_5	330214.NIDE2898	1.447e-59	214.0	COG1596@1|root,COG1596@2|Bacteria,3J17R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR34280931_k127_961302_0	237368.SCABRO_01358	6.085e-126	408.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR34280931_k127_961302_1	118173.KB235914_gene3925	1.145e-122	407.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR34280931_k127_961302_3	1218074.BAXZ01000001_gene144	3.555e-72	253.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR34280931_k127_961302_7	1108045.GORHZ_050_00160	5.681e-23	111.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria,2GP4N@201174|Actinobacteria,4GAPU@85026|Gordoniaceae	201174|Actinobacteria	P	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3,Rieske
## 3731 queries scanned
## Total time (seconds): 9.971896409988403
## Rate: 374.15 q/s