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Overview

ID MAG00297
Name CMS1_bin.107
Sample SMP0010
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Sphingomonadales
Family Sphingomonadaceae
Genus Parasphingorhabdus
Species
Assembly information
Completeness (%) 78.52
Contamination (%) 1.48
GC content (%) 60.0
N50 (bp) 9,780
Genome size (bp) 2,478,225

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2526

Gene name Description KEGG GOs EC E-value Score Sequence
CMS1_k127_1002917_0 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 418.0
CMS1_k127_1002917_1 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 402.0
CMS1_k127_1002917_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 302.0
CMS1_k127_1002917_3 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 293.0
CMS1_k127_1002917_4 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000247 284.0
CMS1_k127_1002917_5 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003556 276.0
CMS1_k127_1002917_6 ICC-like phosphoesterases K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003511 266.0
CMS1_k127_1002917_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 - 2.1.1.197,6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000002201 241.0
CMS1_k127_1002917_8 - - - - 0.000000000000000000000000000000000000000000000000000000000007952 218.0
CMS1_k127_1002917_9 helicase K03724 - - 0.0000000000000000000000000001243 115.0
CMS1_k127_101223_0 protease with the C-terminal PDZ - - - 3.763e-256 814.0
CMS1_k127_101223_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.128e-216 674.0
CMS1_k127_101223_2 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 516.0
CMS1_k127_101223_3 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 415.0
CMS1_k127_101223_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 348.0
CMS1_k127_101223_5 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 289.0
CMS1_k127_101223_6 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000004426 259.0
CMS1_k127_101223_7 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000002114 212.0
CMS1_k127_101223_8 FeS assembly SUF system protein - - - 0.000000000000000000000000000000000000000000002742 164.0
CMS1_k127_1013462_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.244e-320 987.0
CMS1_k127_1013462_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 591.0
CMS1_k127_1013462_2 Cytidylate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004576 268.0
CMS1_k127_1013462_3 - - - - 0.000000000000006313 78.0
CMS1_k127_1013462_4 Protein of unknown function (FYDLN_acid) - - - 0.000000000002865 67.0
CMS1_k127_1020438_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 496.0
CMS1_k127_1020438_1 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 467.0
CMS1_k127_1020438_2 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001227 240.0
CMS1_k127_1020438_3 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000000000000000000000000000000008155 219.0
CMS1_k127_1020438_4 Cys Met metabolism K01761 - 4.4.1.11 0.000000000000000000007351 92.0
CMS1_k127_102871_0 Phage shock protein A K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 306.0
CMS1_k127_102871_1 molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 283.0
CMS1_k127_102871_10 - - - - 0.0000000000000000425 83.0
CMS1_k127_102871_11 - - - - 0.000007018 51.0
CMS1_k127_102871_2 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000000000000000000000000000000000000001918 217.0
CMS1_k127_102871_3 PspC domain K03973 - - 0.000000000000000000000000000000000000000000000008761 177.0
CMS1_k127_102871_4 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.0000000000000000000000000000000000000000001038 160.0
CMS1_k127_102871_5 - - - - 0.000000000000000000000000000000000000000196 152.0
CMS1_k127_102871_6 - - - - 0.00000000000000000000000000000000004008 136.0
CMS1_k127_102871_7 Phage shock protein B K03970 - - 0.00000000000000000000000000000006909 126.0
CMS1_k127_102871_8 - - - - 0.00000000000000000000004299 102.0
CMS1_k127_102871_9 - - - - 0.00000000000000000009783 91.0
CMS1_k127_1056220_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 2.595e-232 743.0
CMS1_k127_1056220_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 449.0
CMS1_k127_1056220_10 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002063 172.0
CMS1_k127_1056220_11 Erythromycin esterase - - - 0.00000000000000000001564 90.0
CMS1_k127_1056220_12 Protein required for attachment to host cells - - - 0.00000000000000004189 87.0
CMS1_k127_1056220_13 - - - - 0.0003874 48.0
CMS1_k127_1056220_2 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 351.0
CMS1_k127_1056220_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 323.0
CMS1_k127_1056220_4 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008475 279.0
CMS1_k127_1056220_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
CMS1_k127_1056220_6 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
CMS1_k127_1056220_7 Head domain of trimeric autotransporter adhesin K21449 - - 0.000000000000000000000000000000000000000000000000000000000000001253 231.0
CMS1_k127_1056220_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000003722 199.0
CMS1_k127_1056220_9 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000000000000000000003665 184.0
CMS1_k127_1061970_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1134.0
CMS1_k127_1061970_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000232 255.0
CMS1_k127_1061970_2 Malic enzyme K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000003143 205.0
CMS1_k127_1061970_3 Peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000005847 181.0
CMS1_k127_1083475_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 463.0
CMS1_k127_1083475_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 442.0
CMS1_k127_1083475_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 424.0
CMS1_k127_1083475_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000003787 61.0
CMS1_k127_1089336_0 Peptidase, M16 K07263 - - 0.0 1137.0
CMS1_k127_1089336_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.427e-222 695.0
CMS1_k127_1089336_10 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 468.0
CMS1_k127_1089336_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 452.0
CMS1_k127_1089336_12 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 457.0
CMS1_k127_1089336_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 405.0
CMS1_k127_1089336_14 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 396.0
CMS1_k127_1089336_15 Phosphate ABC transporter substrate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 394.0
CMS1_k127_1089336_16 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 371.0
CMS1_k127_1089336_17 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
CMS1_k127_1089336_18 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 319.0
CMS1_k127_1089336_19 Nitroreductase family K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 317.0
CMS1_k127_1089336_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.139e-218 684.0
CMS1_k127_1089336_20 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 309.0
CMS1_k127_1089336_21 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
CMS1_k127_1089336_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 295.0
CMS1_k127_1089336_23 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 295.0
CMS1_k127_1089336_24 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002315 270.0
CMS1_k127_1089336_25 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001721 257.0
CMS1_k127_1089336_26 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000000000000006117 212.0
CMS1_k127_1089336_27 peptidase M22 - - - 0.00000000000000000000000000000000000000000000000000000005406 202.0
CMS1_k127_1089336_28 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000002187 178.0
CMS1_k127_1089336_29 Protein of unknown function (DUF2794) - - - 0.000000000000000000000000000000000000000000001436 167.0
CMS1_k127_1089336_3 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.683e-215 676.0
CMS1_k127_1089336_30 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000007724 155.0
CMS1_k127_1089336_31 Acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000008063 127.0
CMS1_k127_1089336_32 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000001083 112.0
CMS1_k127_1089336_33 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000003774 93.0
CMS1_k127_1089336_34 - - - - 0.0000000000004391 72.0
CMS1_k127_1089336_35 - - - - 0.000000004375 58.0
CMS1_k127_1089336_36 - - - - 0.0000007509 53.0
CMS1_k127_1089336_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 5.974e-203 641.0
CMS1_k127_1089336_5 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 602.0
CMS1_k127_1089336_6 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 544.0
CMS1_k127_1089336_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 502.0
CMS1_k127_1089336_8 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 505.0
CMS1_k127_1089336_9 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 481.0
CMS1_k127_1141463_0 Thi4 family - - - 7.069e-273 846.0
CMS1_k127_1141463_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 511.0
CMS1_k127_1141463_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000009739 219.0
CMS1_k127_1141463_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000001186 185.0
CMS1_k127_1141463_4 GtrA-like protein - - - 0.000000000000000000000000005119 115.0
CMS1_k127_1156685_0 Outer membrane protein beta-barrel family - - - 0.0 1175.0
CMS1_k127_1156685_1 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0 1116.0
CMS1_k127_1156685_10 Phosphate ABC transporter substrate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 443.0
CMS1_k127_1156685_11 proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 418.0
CMS1_k127_1156685_12 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 416.0
CMS1_k127_1156685_13 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 394.0
CMS1_k127_1156685_14 Protein of unknown function (DUF3034) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 383.0
CMS1_k127_1156685_15 COG1305 Transglutaminase-like enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 361.0
CMS1_k127_1156685_16 KR domain K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
CMS1_k127_1156685_17 3-phytase K01083 - 3.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 357.0
CMS1_k127_1156685_18 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 334.0
CMS1_k127_1156685_19 Acetyl-coenzyme A transporter 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 347.0
CMS1_k127_1156685_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1050.0
CMS1_k127_1156685_20 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 325.0
CMS1_k127_1156685_21 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 319.0
CMS1_k127_1156685_22 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 304.0
CMS1_k127_1156685_23 ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 299.0
CMS1_k127_1156685_24 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002157 271.0
CMS1_k127_1156685_25 Eukaryotic-type carbonic anhydrase - - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
CMS1_k127_1156685_26 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001308 213.0
CMS1_k127_1156685_27 Bacterial-like globin - - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
CMS1_k127_1156685_28 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000002863 191.0
CMS1_k127_1156685_29 - - - - 0.0000000000000000000000000000000000000000000000001755 184.0
CMS1_k127_1156685_3 Circularly permuted ATP-grasp type 2 - - - 5.481e-262 811.0
CMS1_k127_1156685_30 - - - - 0.000000000000000000000000000000000000000004167 161.0
CMS1_k127_1156685_31 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000002748 140.0
CMS1_k127_1156685_32 - - - - 0.00000000000000005929 81.0
CMS1_k127_1156685_4 GMC oxidoreductase - - - 2.469e-251 792.0
CMS1_k127_1156685_5 Putative diguanylate phosphodiesterase - - - 2.203e-237 756.0
CMS1_k127_1156685_6 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00528 - 1.18.1.2,1.19.1.1 1.124e-203 641.0
CMS1_k127_1156685_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 600.0
CMS1_k127_1156685_8 phosphate-selective porin K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 520.0
CMS1_k127_1156685_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
CMS1_k127_1159255_0 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 582.0
CMS1_k127_1159255_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 349.0
CMS1_k127_1159255_2 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
CMS1_k127_1207081_0 helicase K16899 - 3.6.4.12 2.561e-318 1003.0
CMS1_k127_1207081_1 Histidine kinase - - - 1.697e-221 702.0
CMS1_k127_1207081_2 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 411.0
CMS1_k127_1207081_3 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 401.0
CMS1_k127_1207081_4 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 307.0
CMS1_k127_1207081_5 ATPase or kinase K06925 - - 0.000000000000000000000000000002491 125.0
CMS1_k127_1219582_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 459.0
CMS1_k127_1219582_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 442.0
CMS1_k127_1219582_2 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009489 265.0
CMS1_k127_1219582_3 Pyrrolo-quinoline quinone - - - 0.0000000000000000000008502 97.0
CMS1_k127_1232601_0 LVIVD repeat - - - 0.0 2227.0
CMS1_k127_1232601_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.273e-301 929.0
CMS1_k127_1232601_2 - - - - 2.496e-298 930.0
CMS1_k127_1232601_3 Haem-degrading - - - 1.727e-279 874.0
CMS1_k127_1232601_4 belongs to the aldehyde dehydrogenase family - - - 9.697e-264 818.0
CMS1_k127_1232601_5 Cytochrome c554 and c-prime - - - 7.178e-203 641.0
CMS1_k127_1232601_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 379.0
CMS1_k127_1232601_7 nuclease - - - 0.00000000000000000000000000000000000000002012 157.0
CMS1_k127_1232601_8 Glycine zipper 2TM domain - - - 0.00000000000000000000000001533 113.0
CMS1_k127_1232601_9 - - - - 0.00000000000000000002445 95.0
CMS1_k127_1264178_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.449e-249 773.0
CMS1_k127_1264178_1 membrane metal-binding protein K02238 - - 2.685e-228 728.0
CMS1_k127_1264178_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.565e-219 691.0
CMS1_k127_1264178_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
CMS1_k127_1264178_4 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000000000001921 214.0
CMS1_k127_1264178_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000001271 168.0
CMS1_k127_127057_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1199.0
CMS1_k127_127057_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 308.0
CMS1_k127_127057_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001574 275.0
CMS1_k127_127057_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001704 242.0
CMS1_k127_127057_4 attachment protein - - - 0.00000000000000000000000000000000000000000000000004974 182.0
CMS1_k127_1311287_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 7.564e-214 671.0
CMS1_k127_1311287_1 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 447.0
CMS1_k127_1311287_2 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 374.0
CMS1_k127_1354784_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1726.0
CMS1_k127_1354784_1 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 384.0
CMS1_k127_1354784_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001086 273.0
CMS1_k127_1376720_0 Organic Anion Transporter Polypeptide (OATP) family - - - 7.591e-257 798.0
CMS1_k127_1376720_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.939e-208 652.0
CMS1_k127_1376720_10 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
CMS1_k127_1376720_11 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
CMS1_k127_1376720_12 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
CMS1_k127_1376720_13 response to antibiotic - - - 0.000003537 58.0
CMS1_k127_1376720_14 - - - - 0.000007611 51.0
CMS1_k127_1376720_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 513.0
CMS1_k127_1376720_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 494.0
CMS1_k127_1376720_4 Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate K00220 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 491.0
CMS1_k127_1376720_5 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 470.0
CMS1_k127_1376720_6 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 445.0
CMS1_k127_1376720_7 cell division K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 397.0
CMS1_k127_1376720_8 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 321.0
CMS1_k127_1376720_9 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007334 274.0
CMS1_k127_1380426_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 9.912e-214 668.0
CMS1_k127_1380426_1 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 530.0
CMS1_k127_1380426_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 462.0
CMS1_k127_1380426_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 437.0
CMS1_k127_1380426_4 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 322.0
CMS1_k127_1380426_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 316.0
CMS1_k127_1380426_6 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000005454 103.0
CMS1_k127_1380426_7 Peptidase inhibitor I78 family - - - 0.00000000000000000000004315 101.0
CMS1_k127_1392913_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0 1001.0
CMS1_k127_1392913_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.494e-223 698.0
CMS1_k127_1392913_2 Nitrogen fixation protein fixG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 466.0
CMS1_k127_1392913_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 437.0
CMS1_k127_1392913_4 Peptidase S41 K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 398.0
CMS1_k127_1392913_5 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 323.0
CMS1_k127_1392913_6 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000009107 199.0
CMS1_k127_1392913_7 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000001243 70.0
CMS1_k127_1447260_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 612.0
CMS1_k127_1447260_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 556.0
CMS1_k127_1447260_2 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 529.0
CMS1_k127_1447260_3 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
CMS1_k127_1481369_0 ABC transporter - - - 1.677e-243 755.0
CMS1_k127_1481369_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.701e-242 756.0
CMS1_k127_1481369_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000001144 145.0
CMS1_k127_1481369_3 OST-HTH/LOTUS domain - - - 0.000000000000000000005923 93.0
CMS1_k127_1546433_0 Helicase K03722 - 3.6.4.12 9.827e-305 945.0
CMS1_k127_1546433_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 7.51e-261 811.0
CMS1_k127_1546433_2 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002723 251.0
CMS1_k127_1546433_3 NnrU protein - - - 0.00000000000000000000000000000000000000000000000005718 202.0
CMS1_k127_1546433_4 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000008919 172.0
CMS1_k127_1568248_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 389.0
CMS1_k127_1568248_1 DNA recombination protein K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 300.0
CMS1_k127_1568248_2 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000000000000000002678 122.0
CMS1_k127_1568248_3 META domain - - - 0.0000000000188 70.0
CMS1_k127_1626491_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.336e-249 781.0
CMS1_k127_1626491_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 309.0
CMS1_k127_1626491_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 292.0
CMS1_k127_1626491_3 protein conserved in bacteria K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009331 281.0
CMS1_k127_1626491_4 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000004209 235.0
CMS1_k127_1626491_5 Thioesterase-like superfamily - - - 0.00000000000000000000000000000003058 136.0
CMS1_k127_1653641_0 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 369.0
CMS1_k127_1653641_1 endonuclease III K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 316.0
CMS1_k127_1653641_2 FR47-like protein - - - 0.00000000000000000000000000000000000000000000001401 173.0
CMS1_k127_1653641_3 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000006835 153.0
CMS1_k127_1653641_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000003232 145.0
CMS1_k127_1653641_5 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000003255 142.0
CMS1_k127_1653641_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000001743 78.0
CMS1_k127_1660457_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1229.0
CMS1_k127_1660457_1 peptidase S9 - - - 2.209e-281 881.0
CMS1_k127_1660457_2 membrane K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 586.0
CMS1_k127_1660457_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
CMS1_k127_1660457_4 protein-L-isoaspartate K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000265 198.0
CMS1_k127_1660457_5 protein conserved in bacteria K09991 - - 0.00000000000000001946 89.0
CMS1_k127_1660457_6 transferase activity, transferring glycosyl groups - - - 0.00001308 52.0
CMS1_k127_1668291_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 521.0
CMS1_k127_1668291_1 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 436.0
CMS1_k127_1668291_10 Virulence factor BrkB K07058 - - 0.0000000000000000000004269 101.0
CMS1_k127_1668291_11 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000891 87.0
CMS1_k127_1668291_12 pyridoxamine 5-phosphate - - - 0.000000000000000003852 86.0
CMS1_k127_1668291_13 Sensors of blue-light using FAD - - - 0.000000000000000009795 89.0
CMS1_k127_1668291_14 Bacterial protein of unknown function (DUF883) - - - 0.0006963 48.0
CMS1_k127_1668291_2 COG0668 Small-conductance mechanosensitive channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 392.0
CMS1_k127_1668291_3 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 305.0
CMS1_k127_1668291_4 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 296.0
CMS1_k127_1668291_5 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002809 271.0
CMS1_k127_1668291_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
CMS1_k127_1668291_7 Domain of unknown function (DUF202) - - - 0.000000000000000000000000000000000000000000000001075 177.0
CMS1_k127_1668291_8 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000008729 177.0
CMS1_k127_1668291_9 protein-S-isoprenylcysteine methyltransferase - - - 0.0000000000000000000000000000000000000000005489 159.0
CMS1_k127_16777_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 1.335e-273 858.0
CMS1_k127_16777_1 Aerobic cobaltochelatase subunit CobS K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 597.0
CMS1_k127_16777_2 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 361.0
CMS1_k127_16777_3 molecular chaperone - - - 0.00000000000000005406 82.0
CMS1_k127_1698141_0 Major Facilitator - - - 1.002e-258 806.0
CMS1_k127_1698141_1 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 7.112e-242 760.0
CMS1_k127_1698141_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
CMS1_k127_1748777_0 peptidase U62, modulator of DNA gyrase K03568 - - 5.749e-244 757.0
CMS1_k127_1748777_1 Ammonium Transporter K03320 - - 1.941e-227 710.0
CMS1_k127_1748777_2 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 525.0
CMS1_k127_1748777_3 Belongs to the GMC oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 398.0
CMS1_k127_1748777_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 299.0
CMS1_k127_1748777_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001013 272.0
CMS1_k127_1748777_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002188 199.0
CMS1_k127_1748777_7 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000001291 180.0
CMS1_k127_1748777_8 CAAX protease self-immunity - - - 0.0000000000000000000119 99.0
CMS1_k127_1800789_0 Domain of unknown function DUF11 - - - 0.0 2033.0
CMS1_k127_1800789_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 444.0
CMS1_k127_1800789_2 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004712 248.0
CMS1_k127_1800789_3 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000000001314 138.0
CMS1_k127_1800892_0 protein conserved in bacteria - - - 6.071e-255 796.0
CMS1_k127_1800892_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 411.0
CMS1_k127_1800892_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000002599 230.0
CMS1_k127_1800892_3 Disulfide bond formation protein - - - 0.000000000000000000000000000000000000000000000000000000002615 203.0
CMS1_k127_1800892_4 - - - - 0.0000000000000000000000000000000000000000001738 166.0
CMS1_k127_1807565_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.319e-319 983.0
CMS1_k127_1807565_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 334.0
CMS1_k127_1807565_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003136 287.0
CMS1_k127_1807565_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000002054 269.0
CMS1_k127_1807565_4 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000003597 252.0
CMS1_k127_1807565_5 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000002624 140.0
CMS1_k127_1807565_6 - - - - 0.00000000000000000000000000735 115.0
CMS1_k127_1817412_0 Efflux pump membrane transporter K18138 - - 0.0 1077.0
CMS1_k127_1817412_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 592.0
CMS1_k127_1817412_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585,K18306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 396.0
CMS1_k127_1817412_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 306.0
CMS1_k127_1817412_4 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 302.0
CMS1_k127_1817412_5 KR domain K05296 - 1.1.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
CMS1_k127_1817412_6 SnoaL-like domain - - - 0.00000000000000000000000001235 119.0
CMS1_k127_1818142_0 Ferrous iron transport protein B K04759 - - 7.036e-285 885.0
CMS1_k127_1818142_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.093e-230 717.0
CMS1_k127_1818142_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 425.0
CMS1_k127_1818142_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 414.0
CMS1_k127_1818142_4 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 343.0
CMS1_k127_1818142_5 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004506 276.0
CMS1_k127_1818142_6 RpsU-divergently transcribed K18587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
CMS1_k127_1818142_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
CMS1_k127_1818142_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000008242 222.0
CMS1_k127_1818142_9 Fe2 transport system protein A K04758 - - 0.0000000000000000007561 89.0
CMS1_k127_1820579_0 TonB-dependent receptor - - - 2.053e-308 967.0
CMS1_k127_1820579_1 Aminotransferase class-III - - - 2.901e-242 756.0
CMS1_k127_1820579_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 446.0
CMS1_k127_1820579_3 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 419.0
CMS1_k127_1820579_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 415.0
CMS1_k127_1820579_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 408.0
CMS1_k127_1820579_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000000001667 157.0
CMS1_k127_1820579_7 Rieske 2Fe2S - - - 0.0000001014 55.0
CMS1_k127_1820579_8 Domain of unknown function DUF87 - - - 0.00003017 46.0
CMS1_k127_1829056_0 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 360.0
CMS1_k127_1829056_1 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 308.0
CMS1_k127_1829056_2 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000004329 208.0
CMS1_k127_1829056_3 General secretion pathway protein L - - - 0.00000000000000000000000000000000000007606 156.0
CMS1_k127_1829056_4 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000001732 100.0
CMS1_k127_1829056_5 domain, Protein K13714 - 3.2.1.96,3.5.1.28 0.00000000000000000003145 99.0
CMS1_k127_1829056_6 Cytochrome p450 - - - 0.0000000000000007711 79.0
CMS1_k127_1829442_0 Dicarboxylate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 607.0
CMS1_k127_1829442_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 350.0
CMS1_k127_1829442_2 protein conserved in bacteria K09978 - - 0.000000000000000000000000000000000000000000000004551 175.0
CMS1_k127_1829442_3 YnbE-like lipoprotein - - - 0.00000000000001803 78.0
CMS1_k127_1833177_0 Peptidase dimerisation domain - - - 1.549e-264 828.0
CMS1_k127_1833177_1 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 437.0
CMS1_k127_1833177_2 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006671 233.0
CMS1_k127_1833177_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000007279 229.0
CMS1_k127_1833177_4 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000000000000000000369 177.0
CMS1_k127_1833177_5 - - - - 0.00000000000000000004264 93.0
CMS1_k127_1833177_6 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000002655 60.0
CMS1_k127_1842398_0 DNA mediated transformation - - - 1.395e-194 628.0
CMS1_k127_1842398_1 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 443.0
CMS1_k127_1842398_2 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000005258 179.0
CMS1_k127_1849793_0 Alpha amylase, catalytic domain K00690 - 2.4.1.7 5.053e-203 648.0
CMS1_k127_1849793_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 477.0
CMS1_k127_1849793_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 357.0
CMS1_k127_1849793_3 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 296.0
CMS1_k127_1856100_0 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 9.616e-225 702.0
CMS1_k127_1856100_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 493.0
CMS1_k127_1856100_11 transport system auxiliary component K18480 - - 0.00000000000000000000000000000000000000126 155.0
CMS1_k127_1856100_12 - - - - 0.000000000000000000000000001908 118.0
CMS1_k127_1856100_13 response to cobalt ion - - - 0.000000000000000000000000003896 117.0
CMS1_k127_1856100_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 421.0
CMS1_k127_1856100_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 391.0
CMS1_k127_1856100_4 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 383.0
CMS1_k127_1856100_5 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 383.0
CMS1_k127_1856100_6 Putative S-adenosyl-L-methionine-dependent methyltransferase K18164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 378.0
CMS1_k127_1856100_7 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
CMS1_k127_1856100_8 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000000000000000000000000000000003986 198.0
CMS1_k127_1856100_9 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000008754 195.0
CMS1_k127_1857761_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 3.182e-199 633.0
CMS1_k127_1857761_1 Chain-length determining protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 595.0
CMS1_k127_1857761_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 574.0
CMS1_k127_1857761_3 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 346.0
CMS1_k127_1857761_4 involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 347.0
CMS1_k127_1857761_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
CMS1_k127_1857761_6 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 246.0
CMS1_k127_1857761_7 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000185 202.0
CMS1_k127_1857761_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000003093 165.0
CMS1_k127_1857761_9 acyl carrier protein - - - 0.0000000000000000000000000000004484 123.0
CMS1_k127_1878108_0 fumarate reductase K05898 - 1.3.99.4 3.563e-212 667.0
CMS1_k127_1878108_1 Rieske [2Fe-2S] domain K15982 - 1.14.13.142 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 577.0
CMS1_k127_1878108_2 PFAM Acyl-CoA dehydrogenase, type 2, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 568.0
CMS1_k127_1878108_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 376.0
CMS1_k127_1878108_4 Glyoxalase bleomycin resistance protein dioxygenase K16049 - 1.13.11.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 355.0
CMS1_k127_1878108_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001204 244.0
CMS1_k127_194426_0 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 340.0
CMS1_k127_194426_1 Domain of unknown function (DUF4071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004293 239.0
CMS1_k127_1954566_0 TonB-dependent receptor - - - 1e-322 1007.0
CMS1_k127_1954566_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 565.0
CMS1_k127_1954566_2 NADP-dependent oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 441.0
CMS1_k127_1954566_3 Enoyl-(Acyl carrier protein) reductase K05296 - 1.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
CMS1_k127_1954566_4 COG4308 Limonene-1,2-epoxide hydrolase K10533 - 3.3.2.8 0.0000000000000000000000000000005715 126.0
CMS1_k127_1985233_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1415.0
CMS1_k127_1985233_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001665 257.0
CMS1_k127_1985233_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
CMS1_k127_2015516_0 helicase K03724 - - 0.0 1204.0
CMS1_k127_2015516_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 458.0
CMS1_k127_2015516_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 385.0
CMS1_k127_2015516_3 histone deacetylase - - - 0.000000000000000000000000002115 112.0
CMS1_k127_2015935_0 Patatin-like phospholipase K07001 - - 2.6e-207 661.0
CMS1_k127_2015935_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 499.0
CMS1_k127_2015935_2 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 358.0
CMS1_k127_2015935_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 334.0
CMS1_k127_2015935_4 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000000000000000000002787 192.0
CMS1_k127_2015935_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000003833 118.0
CMS1_k127_2015935_6 Protein of unknown function (DUF2793) - - - 0.00000000000000000000000000004981 121.0
CMS1_k127_2015935_7 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000002376 108.0
CMS1_k127_2015935_8 - - - - 0.0000000000000001879 85.0
CMS1_k127_2028790_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.117e-245 766.0
CMS1_k127_2028790_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 433.0
CMS1_k127_2037050_0 peptidase S9 K01354 - 3.4.21.83 0.0 1099.0
CMS1_k127_2037050_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007576 277.0
CMS1_k127_2037050_2 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000006229 194.0
CMS1_k127_2037050_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000003302 98.0
CMS1_k127_2046156_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1240.0
CMS1_k127_2046156_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 2.691e-227 706.0
CMS1_k127_2046156_2 acyl-CoA dehydrogenase - - - 1.207e-215 674.0
CMS1_k127_2046156_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 411.0
CMS1_k127_2046156_4 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 316.0
CMS1_k127_2046156_5 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 308.0
CMS1_k127_205530_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.848e-246 764.0
CMS1_k127_205530_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.896e-228 711.0
CMS1_k127_205530_10 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000001682 136.0
CMS1_k127_205530_11 - - - - 0.0000000000000000002394 91.0
CMS1_k127_205530_12 molecular chaperone - - - 0.0000000000000001134 80.0
CMS1_k127_205530_13 - - - - 0.000001771 49.0
CMS1_k127_205530_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.602e-202 642.0
CMS1_k127_205530_3 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 480.0
CMS1_k127_205530_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 393.0
CMS1_k127_205530_5 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 372.0
CMS1_k127_205530_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 359.0
CMS1_k127_205530_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 325.0
CMS1_k127_205530_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 303.0
CMS1_k127_205530_9 Histidine phosphotransferase C-terminal domain K13588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
CMS1_k127_2069149_0 Trypsin-like serine protease - - - 1.682e-218 706.0
CMS1_k127_2069149_1 protein conserved in bacteria K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 549.0
CMS1_k127_2069149_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000008142 102.0
CMS1_k127_2069149_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00007774 45.0
CMS1_k127_2069149_2 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 299.0
CMS1_k127_2069149_3 UMP catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003146 258.0
CMS1_k127_2069149_4 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
CMS1_k127_2069149_5 endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000002087 203.0
CMS1_k127_2069149_6 response regulator K11443 - - 0.0000000000000000000000000000000000000000000000000009806 185.0
CMS1_k127_2069149_7 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000001862 181.0
CMS1_k127_2069149_8 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000001042 144.0
CMS1_k127_2069149_9 Protein of unknown function (DUF3572) - - - 0.000000000000000000000002083 105.0
CMS1_k127_2071516_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1249.0
CMS1_k127_2071516_1 Belongs to the AAA ATPase family K13525 - - 0.0 1196.0
CMS1_k127_2071516_10 Alkaline phosphatase with broad substrate specificity K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 291.0
CMS1_k127_2071516_11 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
CMS1_k127_2071516_12 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
CMS1_k127_2071516_13 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000005138 231.0
CMS1_k127_2071516_14 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
CMS1_k127_2071516_15 Biopolymer transport protein K03560 - - 0.000000000000000000000000000000000000000000000000000008914 194.0
CMS1_k127_2071516_16 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000003518 188.0
CMS1_k127_2071516_17 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000001297 186.0
CMS1_k127_2071516_18 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.0000000000000000000000000000000000000009414 149.0
CMS1_k127_2071516_19 - - - - 0.0000000000000000000000000000000000002754 142.0
CMS1_k127_2071516_2 Peptidase, M16 - - - 0.0 1173.0
CMS1_k127_2071516_20 Glyoxalase - - - 0.0000000000000000000000000000000002413 137.0
CMS1_k127_2071516_21 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000001102 136.0
CMS1_k127_2071516_22 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0001454 46.0
CMS1_k127_2071516_3 Involved in the TonB-independent uptake of proteins K03641 - - 4.364e-237 738.0
CMS1_k127_2071516_4 Amidohydrolase family K06015 - 3.5.1.81 1.046e-236 745.0
CMS1_k127_2071516_5 Thiol disulfide interchange protein - - - 2.767e-229 729.0
CMS1_k127_2071516_6 amidohydrolase - - - 2.134e-194 618.0
CMS1_k127_2071516_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 529.0
CMS1_k127_2071516_8 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
CMS1_k127_2071516_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
CMS1_k127_2073762_0 acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0 1303.0
CMS1_k127_2073762_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0 1177.0
CMS1_k127_2073762_10 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 568.0
CMS1_k127_2073762_11 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 564.0
CMS1_k127_2073762_12 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 504.0
CMS1_k127_2073762_13 N-terminal domain of oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 501.0
CMS1_k127_2073762_14 acyl-CoA dehydrogenase K00255 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 498.0
CMS1_k127_2073762_15 Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 308.0
CMS1_k127_2073762_16 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001186 247.0
CMS1_k127_2073762_17 Acetone carboxylase, gamma subunit K10856 - 6.4.1.6 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
CMS1_k127_2073762_18 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000004414 156.0
CMS1_k127_2073762_19 Biopolymer transport protein K03559 - - 0.00000000000000000000003876 104.0
CMS1_k127_2073762_2 TonB dependent receptor - - - 0.0 1138.0
CMS1_k127_2073762_20 - - - - 0.0000000000797 71.0
CMS1_k127_2073762_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 4.901e-319 978.0
CMS1_k127_2073762_4 helix_turn_helix, Lux Regulon K03556 - - 2.073e-295 932.0
CMS1_k127_2073762_5 TonB dependent receptor - - - 7.88e-288 901.0
CMS1_k127_2073762_6 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.569e-240 758.0
CMS1_k127_2073762_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.986e-233 734.0
CMS1_k127_2073762_8 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 1.679e-209 663.0
CMS1_k127_2073762_9 AsmA-like C-terminal region K07290 - - 6.087e-199 638.0
CMS1_k127_2082197_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 4.148e-200 626.0
CMS1_k127_2082197_1 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 559.0
CMS1_k127_2082197_2 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 571.0
CMS1_k127_2082197_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 404.0
CMS1_k127_2082197_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004482 241.0
CMS1_k127_2082197_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000188 211.0
CMS1_k127_2082197_6 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002642 211.0
CMS1_k127_2082197_7 Ribosomal protein S6 modification protein - - - 0.00000000000000000000000003942 109.0
CMS1_k127_2102991_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 609.0
CMS1_k127_2102991_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 541.0
CMS1_k127_2102991_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 526.0
CMS1_k127_2102991_3 - - - - 0.000000000000000000000000000000000000000005219 160.0
CMS1_k127_2111331_0 receptor - - - 1.44e-245 777.0
CMS1_k127_2111331_1 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 602.0
CMS1_k127_2111331_2 type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 464.0
CMS1_k127_2111331_3 pilus assembly protein TadB K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 389.0
CMS1_k127_2111331_4 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
CMS1_k127_2111331_5 Pilus assembly protein CpaD K02281 - - 0.000000000000000000000000000000000000000000000000000001951 197.0
CMS1_k127_2111331_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002899 176.0
CMS1_k127_2111331_7 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00001323 47.0
CMS1_k127_2162816_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 352.0
CMS1_k127_2162816_1 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
CMS1_k127_2162816_2 protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 249.0
CMS1_k127_2162816_3 Acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001233 216.0
CMS1_k127_2162816_4 Nudix hydrolase - - - 0.00000002713 57.0
CMS1_k127_2189574_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.524e-278 862.0
CMS1_k127_2189574_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.187e-246 764.0
CMS1_k127_2189574_10 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
CMS1_k127_2189574_11 cytochrome C K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 262.0
CMS1_k127_2189574_12 Bacterial regulatory proteins, tetR family - - - 0.00000000001655 67.0
CMS1_k127_2189574_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 2.277e-220 689.0
CMS1_k127_2189574_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 1.135e-209 655.0
CMS1_k127_2189574_4 rod shape-determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 463.0
CMS1_k127_2189574_5 tRNA synthetase, class II K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 456.0
CMS1_k127_2189574_6 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 447.0
CMS1_k127_2189574_7 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 436.0
CMS1_k127_2189574_8 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
CMS1_k127_2189574_9 homocysteine K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 348.0
CMS1_k127_2212553_0 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 568.0
CMS1_k127_2212553_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 445.0
CMS1_k127_2212553_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002985 186.0
CMS1_k127_2212553_3 - - - - 0.00000000000000000000000000000000000002108 153.0
CMS1_k127_2212553_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000001482 129.0
CMS1_k127_2213763_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 1.355e-261 826.0
CMS1_k127_2213763_1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 9.312e-213 668.0
CMS1_k127_2213763_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 319.0
CMS1_k127_2213763_11 MazG family K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
CMS1_k127_2213763_12 Histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000057 287.0
CMS1_k127_2213763_13 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009254 260.0
CMS1_k127_2213763_14 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005245 248.0
CMS1_k127_2213763_15 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000002079 230.0
CMS1_k127_2213763_16 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000005199 219.0
CMS1_k127_2213763_17 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
CMS1_k127_2213763_18 Oligoketide cyclase lipid transport protein K18588 - - 0.00000000000000000000000000000000000000000000000000000007158 200.0
CMS1_k127_2213763_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 543.0
CMS1_k127_2213763_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 538.0
CMS1_k127_2213763_4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 538.0
CMS1_k127_2213763_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 527.0
CMS1_k127_2213763_6 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 458.0
CMS1_k127_2213763_7 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 439.0
CMS1_k127_2213763_8 LuxR family transcriptional regulator K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 425.0
CMS1_k127_2213763_9 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 335.0
CMS1_k127_2218604_0 CobN/Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.0 1817.0
CMS1_k127_2218604_1 5-aminolevulinic acid synthase - - - 5.425e-228 709.0
CMS1_k127_2218604_10 Protein of unknown function (DUF3623) - - - 0.00000000000000000000000000000000000000000000000000000000000001901 225.0
CMS1_k127_2218604_11 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000001367 200.0
CMS1_k127_2218604_12 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000008712 188.0
CMS1_k127_2218604_13 Photosynthetic complex assembly protein - - - 0.0000000000000000000000000000003359 132.0
CMS1_k127_2218604_14 - - - - 0.000000000000000000000000005248 119.0
CMS1_k127_2218604_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 3.052e-227 717.0
CMS1_k127_2218604_3 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 607.0
CMS1_k127_2218604_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 554.0
CMS1_k127_2218604_5 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP K02588,K04037 - 1.18.6.1,1.3.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 516.0
CMS1_k127_2218604_6 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 344.0
CMS1_k127_2218604_7 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 340.0
CMS1_k127_2218604_8 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
CMS1_k127_2218604_9 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004454 269.0
CMS1_k127_2221803_0 membrane - - - 0.0 1248.0
CMS1_k127_2221803_1 enoyl-CoA hydratase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.002e-291 912.0
CMS1_k127_2221803_10 transcriptional regulator - - - 0.00000000000000000000000000000000000000003456 161.0
CMS1_k127_2221803_2 Carboxyl transferase domain K13778 - 6.4.1.5 5.519e-236 741.0
CMS1_k127_2221803_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.694e-195 616.0
CMS1_k127_2221803_4 acyl-CoA dehydrogenase - - - 5.095e-195 614.0
CMS1_k127_2221803_5 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 524.0
CMS1_k127_2221803_6 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 467.0
CMS1_k127_2221803_7 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000004646 254.0
CMS1_k127_2221803_8 nucleoside K03317 - - 0.0000000000000000000000000000000000000000000001222 169.0
CMS1_k127_2221803_9 Belongs to the uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000007148 173.0
CMS1_k127_2269764_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.851e-318 984.0
CMS1_k127_2269764_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 427.0
CMS1_k127_2269764_2 ATPase involved in DNA replication - - - 0.00000000000000000000000000000000000000004954 158.0
CMS1_k127_2284470_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 408.0
CMS1_k127_2284470_1 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 382.0
CMS1_k127_2284470_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 299.0
CMS1_k127_2284470_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 295.0
CMS1_k127_2284470_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 242.0
CMS1_k127_2284470_5 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000008624 157.0
CMS1_k127_2284470_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000005442 144.0
CMS1_k127_2284470_7 - - - - 0.000000000000000002189 88.0
CMS1_k127_2307190_0 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1082.0
CMS1_k127_2307190_1 TonB-dependent receptor - - - 5.79e-275 870.0
CMS1_k127_2307190_10 SnoaL-like domain - - - 0.000000000000000000000000003264 117.0
CMS1_k127_2307190_2 PFAM Rieske 2Fe-2S domain - - - 3.866e-225 706.0
CMS1_k127_2307190_3 Cytochrome P450 - - - 1.178e-217 682.0
CMS1_k127_2307190_4 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
CMS1_k127_2307190_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 332.0
CMS1_k127_2307190_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 287.0
CMS1_k127_2307190_7 Toxic anion resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001234 276.0
CMS1_k127_2307190_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001442 234.0
CMS1_k127_2307190_9 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
CMS1_k127_2346517_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 497.0
CMS1_k127_2346517_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 391.0
CMS1_k127_2346517_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000516 283.0
CMS1_k127_2346517_3 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
CMS1_k127_2346517_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 251.0
CMS1_k127_2346517_5 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.0000000000000000000000000000000000000000000001224 171.0
CMS1_k127_2346517_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000005574 119.0
CMS1_k127_2346517_7 - - - - 0.000000000000001662 78.0
CMS1_k127_2346517_8 - - - - 0.00000005589 60.0
CMS1_k127_2368702_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 579.0
CMS1_k127_2368702_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
CMS1_k127_2368702_2 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 534.0
CMS1_k127_2368702_3 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 474.0
CMS1_k127_2368702_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 343.0
CMS1_k127_2368702_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
CMS1_k127_2368702_6 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008862 275.0
CMS1_k127_2368702_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
CMS1_k127_2368702_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000003309 177.0
CMS1_k127_2368702_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001962 164.0
CMS1_k127_2369932_0 Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 406.0
CMS1_k127_2369932_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 297.0
CMS1_k127_2369932_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000002156 234.0
CMS1_k127_238191_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1086.0
CMS1_k127_238191_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.804e-230 717.0
CMS1_k127_238191_10 Flp pilus assembly protein TadG - - - 0.0000000000000000000000000000000000000000005065 166.0
CMS1_k127_238191_11 Septum formation initiator - - - 0.00000000000000000000000000000000003865 138.0
CMS1_k127_238191_12 Domain of unknown function (DUF4170) - - - 0.000000000000000000000000000001081 122.0
CMS1_k127_238191_14 - - - - 0.000000000000000000000000003196 118.0
CMS1_k127_238191_15 - - - - 0.00000000001274 72.0
CMS1_k127_238191_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 3.015e-226 707.0
CMS1_k127_238191_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 1.111e-222 701.0
CMS1_k127_238191_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 554.0
CMS1_k127_238191_5 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 472.0
CMS1_k127_238191_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005318 265.0
CMS1_k127_238191_7 PFAM TadE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
CMS1_k127_238191_8 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000001883 221.0
CMS1_k127_238191_9 EF hand - - - 0.000000000000000000000000000000000000000000000007722 177.0
CMS1_k127_2392954_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 559.0
CMS1_k127_2392954_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003791 275.0
CMS1_k127_2392954_2 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000002115 190.0
CMS1_k127_2417331_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.268e-196 623.0
CMS1_k127_2417331_1 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 608.0
CMS1_k127_2417331_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
CMS1_k127_2417331_3 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000002151 152.0
CMS1_k127_2417331_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000002944 133.0
CMS1_k127_2417331_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000003291 106.0
CMS1_k127_2417331_6 Nuclear transport factor 2 (NTF2) domain K01822 - 5.3.3.1 0.0000000000000000000000003726 109.0
CMS1_k127_2490266_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 595.0
CMS1_k127_2490266_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 515.0
CMS1_k127_2490266_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000005871 135.0
CMS1_k127_2490266_11 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000001099 118.0
CMS1_k127_2490266_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 448.0
CMS1_k127_2490266_3 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 330.0
CMS1_k127_2490266_4 Antirepressor regulating drug resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 310.0
CMS1_k127_2490266_5 - - - - 0.0000000000000000000000000000000000000000000000000000000006269 211.0
CMS1_k127_2490266_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000002791 184.0
CMS1_k127_2490266_7 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000000000000000000000211 194.0
CMS1_k127_2490266_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000008486 166.0
CMS1_k127_2490266_9 Domain of unknown function (DUF1476) - - - 0.0000000000000000000000000000000000000000001823 162.0
CMS1_k127_2505819_0 protein conserved in bacteria K09800 - - 1.289e-243 789.0
CMS1_k127_2505819_1 COG0729 Outer membrane protein K07278 - - 1.466e-199 644.0
CMS1_k127_2505819_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 235.0
CMS1_k127_2505819_3 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000001957 116.0
CMS1_k127_2573293_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.501e-276 871.0
CMS1_k127_2573293_1 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 5.49e-232 731.0
CMS1_k127_2573293_10 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000001215 200.0
CMS1_k127_2573293_11 DNA-binding protein K11940 - - 0.00000000000000000000000000000000000000002771 154.0
CMS1_k127_2573293_12 - - - - 0.000000000000000000000000001303 115.0
CMS1_k127_2573293_13 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000000001123 94.0
CMS1_k127_2573293_14 Response regulator, receiver - - - 0.000000000000000121 84.0
CMS1_k127_2573293_15 Serine aminopeptidase, S33 - - - 0.00000000000007603 75.0
CMS1_k127_2573293_2 Protein of unknown function (DUF1298) - - - 9.874e-196 623.0
CMS1_k127_2573293_3 Domain of unknown function (DUF3336) K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 595.0
CMS1_k127_2573293_4 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 418.0
CMS1_k127_2573293_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 379.0
CMS1_k127_2573293_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 323.0
CMS1_k127_2573293_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 303.0
CMS1_k127_2573293_8 - - - - 0.000000000000000000000000000000000000000000000000000000000001306 220.0
CMS1_k127_2573293_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000002312 212.0
CMS1_k127_2586360_0 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 581.0
CMS1_k127_2586360_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 396.0
CMS1_k127_2586360_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 326.0
CMS1_k127_2586360_3 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 292.0
CMS1_k127_2586360_4 Alpha beta hydrolase K18092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 272.0
CMS1_k127_2586360_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000002217 173.0
CMS1_k127_2609257_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.156e-220 689.0
CMS1_k127_2609257_1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.439e-216 676.0
CMS1_k127_2609257_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 499.0
CMS1_k127_2609257_3 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 420.0
CMS1_k127_2609257_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
CMS1_k127_2609257_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000347 158.0
CMS1_k127_2609257_6 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000000195 153.0
CMS1_k127_2609257_7 - - - - 0.00000000000000000000008864 112.0
CMS1_k127_2609257_8 Type II secretion system (T2SS), protein N K02463 - - 0.00000000000000000003706 96.0
CMS1_k127_2609257_9 PFAM Amidase K01426 - 3.5.1.4 0.00000009774 59.0
CMS1_k127_267197_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 5.943e-275 865.0
CMS1_k127_267197_1 Bacterial protein of unknown function (DUF853) K06915 - - 3.535e-271 841.0
CMS1_k127_267197_10 Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 439.0
CMS1_k127_267197_11 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 419.0
CMS1_k127_267197_12 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 319.0
CMS1_k127_267197_13 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 292.0
CMS1_k127_267197_14 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000499 257.0
CMS1_k127_267197_15 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000000005622 218.0
CMS1_k127_267197_16 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000009066 186.0
CMS1_k127_267197_17 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000007688 156.0
CMS1_k127_267197_18 Ribbon-helix-helix domain - - - 0.0000000000000000000000000001096 118.0
CMS1_k127_267197_2 Deoxyribodipyrimidine photo-lyase K06876 - - 6.344e-261 820.0
CMS1_k127_267197_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.598e-203 646.0
CMS1_k127_267197_4 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 536.0
CMS1_k127_267197_5 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 534.0
CMS1_k127_267197_6 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 516.0
CMS1_k127_267197_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 459.0
CMS1_k127_267197_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 443.0
CMS1_k127_267197_9 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 444.0
CMS1_k127_2684163_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.689e-250 780.0
CMS1_k127_2684163_1 argininosuccinate lyase K01755 - 4.3.2.1 8.886e-228 714.0
CMS1_k127_2684163_10 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000008481 217.0
CMS1_k127_2684163_11 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000003596 124.0
CMS1_k127_2684163_12 MAPEG family - - - 0.000000000000000000000003352 106.0
CMS1_k127_2684163_13 - - - - 0.0000000000000000006304 89.0
CMS1_k127_2684163_14 - - - - 0.000006107 49.0
CMS1_k127_2684163_15 - - - - 0.00005265 51.0
CMS1_k127_2684163_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 4.259e-205 644.0
CMS1_k127_2684163_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 601.0
CMS1_k127_2684163_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 576.0
CMS1_k127_2684163_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
CMS1_k127_2684163_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 371.0
CMS1_k127_2684163_7 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
CMS1_k127_2684163_8 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
CMS1_k127_2684163_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000001183 229.0
CMS1_k127_2700296_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 334.0
CMS1_k127_2700296_1 Protein conserved in bacteria K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 333.0
CMS1_k127_2700296_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000005569 134.0
CMS1_k127_2700296_3 Peptidase dimerisation domain - - - 0.000000000000000000000000158 108.0
CMS1_k127_2702006_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 486.0
CMS1_k127_2702006_1 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 349.0
CMS1_k127_2702006_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 342.0
CMS1_k127_2702006_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002472 261.0
CMS1_k127_2702006_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000005354 194.0
CMS1_k127_2702006_5 protein conserved in bacteria K09984 - - 0.0000000000000000000000000003887 118.0
CMS1_k127_2704550_0 amino acid peptide transporter K03305 - - 8.925e-256 797.0
CMS1_k127_2704550_1 amidohydrolase - - - 4.829e-224 711.0
CMS1_k127_2704550_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 582.0
CMS1_k127_2704550_3 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 528.0
CMS1_k127_2704550_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 531.0
CMS1_k127_2704550_5 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 461.0
CMS1_k127_2704550_6 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
CMS1_k127_2704550_7 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000003851 162.0
CMS1_k127_2704550_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000003487 141.0
CMS1_k127_2704577_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 4.359e-291 908.0
CMS1_k127_2704577_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 550.0
CMS1_k127_2704577_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000002613 203.0
CMS1_k127_2704577_3 Lipopolysaccharide-assembly K03643 - - 0.000000000000000000000000000000000000000000000000000008071 194.0
CMS1_k127_2704577_4 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001584 196.0
CMS1_k127_2704577_5 Domain of unknown function (DUF4402) - - - 0.00000000000000000000000000000001927 133.0
CMS1_k127_2747952_0 GMC oxidoreductase - - - 1.885e-205 650.0
CMS1_k127_2747952_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 424.0
CMS1_k127_2747952_10 - - - - 0.000000000000000000000000001452 117.0
CMS1_k127_2747952_12 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000001606 50.0
CMS1_k127_2747952_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 389.0
CMS1_k127_2747952_3 NAD(P)H-binding K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 397.0
CMS1_k127_2747952_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 297.0
CMS1_k127_2747952_5 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001973 280.0
CMS1_k127_2747952_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
CMS1_k127_2747952_7 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000167 189.0
CMS1_k127_2747952_8 intracellular protease amidase - - - 0.000000000000000000000000000000000000000000000008863 171.0
CMS1_k127_2747952_9 - - - - 0.0000000000000000000000000000001653 124.0
CMS1_k127_2758166_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.065e-291 902.0
CMS1_k127_2758166_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 1.305e-278 877.0
CMS1_k127_2758166_2 Chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 323.0
CMS1_k127_2758166_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 291.0
CMS1_k127_2758166_4 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000004883 218.0
CMS1_k127_2758166_5 Arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000001212 184.0
CMS1_k127_2758166_6 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000006747 175.0
CMS1_k127_2758166_7 Regulatory protein RecX K03565 - - 0.00000000000000000000000000000000000000000002861 168.0
CMS1_k127_2758166_8 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000158 160.0
CMS1_k127_2758166_9 Cold shock K03704 - - 0.000000000000000000000000000000000000000003403 163.0
CMS1_k127_2761587_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 405.0
CMS1_k127_2761587_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 334.0
CMS1_k127_2761587_2 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000005345 158.0
CMS1_k127_2761587_3 - - - - 0.00000000000148 73.0
CMS1_k127_2774123_0 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 1.715e-266 826.0
CMS1_k127_2774123_1 metallo-beta-lactamase K12574 - - 5.647e-262 817.0
CMS1_k127_2774123_10 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000004271 81.0
CMS1_k127_2774123_11 - - - - 0.00000004826 65.0
CMS1_k127_2774123_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.962e-201 637.0
CMS1_k127_2774123_3 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 414.0
CMS1_k127_2774123_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 381.0
CMS1_k127_2774123_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 368.0
CMS1_k127_2774123_6 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
CMS1_k127_2774123_7 - - - - 0.0000000000000000000000000000000000008199 141.0
CMS1_k127_2774123_8 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000007421 130.0
CMS1_k127_2774123_9 Protein of unknown function (DUF1467) - - - 0.00000000000000000000003284 101.0
CMS1_k127_2774207_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.383e-263 816.0
CMS1_k127_2774207_1 AMP-binding enzyme C-terminal domain K00666 - - 1.227e-220 695.0
CMS1_k127_2774207_2 cytochrome P450 - - - 1.053e-198 632.0
CMS1_k127_2774207_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 370.0
CMS1_k127_2779952_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3214.0
CMS1_k127_2779952_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.992e-293 923.0
CMS1_k127_2779952_10 part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes K14987 - - 0.000000000000000000000000000000000000000000000000000000001611 209.0
CMS1_k127_2779952_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001697 207.0
CMS1_k127_2779952_12 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000006775 186.0
CMS1_k127_2779952_13 Uncharacterized conserved protein (DUF2267) - - - 0.00000000000000000000000000000331 125.0
CMS1_k127_2779952_14 family. transcriptional regulator K01420 - - 0.0000000000000000000000000001626 124.0
CMS1_k127_2779952_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.052e-272 860.0
CMS1_k127_2779952_3 Erythromycin esterase - - - 1.631e-218 684.0
CMS1_k127_2779952_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 477.0
CMS1_k127_2779952_5 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 330.0
CMS1_k127_2779952_6 Belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 298.0
CMS1_k127_2779952_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
CMS1_k127_2779952_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000001108 217.0
CMS1_k127_2779952_9 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000001188 219.0
CMS1_k127_2785908_0 fumarate reductase K05898 - 1.3.99.4 1.105e-254 796.0
CMS1_k127_2785908_1 acyl-CoA dehydrogenase - - - 1.407e-207 650.0
CMS1_k127_2785908_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 471.0
CMS1_k127_2785908_3 Dehydrogenase - - - 0.00000000000000000000002805 110.0
CMS1_k127_2785908_4 HI0933-like protein K05898 - 1.3.99.4 0.0000000000007326 72.0
CMS1_k127_2801608_0 Sulfate transporter K03321 - - 4.04e-247 773.0
CMS1_k127_2801608_1 cytochrome C K02198 - - 6.065e-234 731.0
CMS1_k127_2801608_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 357.0
CMS1_k127_2801608_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000006127 207.0
CMS1_k127_2801608_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000001556 194.0
CMS1_k127_2801608_5 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000002002 160.0
CMS1_k127_2801608_6 XRE family transcriptional regulator - - - 0.0000000000000000000000000000000000000002337 151.0
CMS1_k127_2808246_0 Penicillin-binding Protein K05515 - 3.4.16.4 8.959e-312 967.0
CMS1_k127_2808246_1 COG1012 NAD-dependent aldehyde dehydrogenases K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 8.575e-252 781.0
CMS1_k127_2808246_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 2.152e-220 691.0
CMS1_k127_2808246_3 rod shape-determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 602.0
CMS1_k127_2808246_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 539.0
CMS1_k127_2808246_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 346.0
CMS1_k127_2808246_6 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 298.0
CMS1_k127_2808246_7 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000002709 184.0
CMS1_k127_281460_0 - - - - 2.008e-200 633.0
CMS1_k127_281460_1 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 325.0
CMS1_k127_281460_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 312.0
CMS1_k127_281460_3 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000001634 234.0
CMS1_k127_2821006_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.326e-220 691.0
CMS1_k127_2821006_1 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 554.0
CMS1_k127_2821006_2 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 543.0
CMS1_k127_2821006_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 377.0
CMS1_k127_2821006_4 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 377.0
CMS1_k127_2821006_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 325.0
CMS1_k127_2821006_6 Bacterial PH domain K09167 - - 0.00000000000000000000000000000000000000004018 160.0
CMS1_k127_2821006_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000007149 151.0
CMS1_k127_2821006_8 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000001021 130.0
CMS1_k127_2821006_9 Dodecin K09165 - - 0.0000000000000000000418 101.0
CMS1_k127_2830710_0 protein conserved in bacteria - - - 7.705e-270 842.0
CMS1_k127_2830710_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 1.611e-236 737.0
CMS1_k127_2830710_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000004408 222.0
CMS1_k127_2830710_11 Nickel/cobalt transporter regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002698 223.0
CMS1_k127_2830710_12 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
CMS1_k127_2830710_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000004104 202.0
CMS1_k127_2830710_14 small heat shock protein - - - 0.00000000000000000000000000000000000000000000001106 175.0
CMS1_k127_2830710_15 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000971 184.0
CMS1_k127_2830710_16 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000001966 175.0
CMS1_k127_2830710_17 Protein of unknown function (DUF1153) - - - 0.0000000000000000000000000000000218 132.0
CMS1_k127_2830710_2 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 605.0
CMS1_k127_2830710_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 533.0
CMS1_k127_2830710_4 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 482.0
CMS1_k127_2830710_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 455.0
CMS1_k127_2830710_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 371.0
CMS1_k127_2830710_7 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 304.0
CMS1_k127_2830710_8 alcohol dehydrogenase K12957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 280.0
CMS1_k127_2830710_9 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
CMS1_k127_2840321_0 antiporter - - - 3.167e-261 818.0
CMS1_k127_2840321_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.076e-212 666.0
CMS1_k127_2840321_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 378.0
CMS1_k127_2840321_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
CMS1_k127_2840321_4 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000000000000000000005969 216.0
CMS1_k127_2840321_5 - - - - 0.0000000000000000000000000000000000000000000001424 178.0
CMS1_k127_2840321_6 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000002484 174.0
CMS1_k127_2846221_0 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 443.0
CMS1_k127_2846221_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 355.0
CMS1_k127_2846221_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 323.0
CMS1_k127_2846221_3 NADH dehydrogenase (quinone) activity K03880 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031960,GO:0031966,GO:0031967,GO:0031975,GO:0032870,GO:0032981,GO:0032991,GO:0033108,GO:0033993,GO:0034622,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048545,GO:0050136,GO:0050896,GO:0051384,GO:0051716,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0070887,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000007659 145.0
CMS1_k127_284914_0 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 524.0
CMS1_k127_284914_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000111 256.0
CMS1_k127_284914_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000001318 187.0
CMS1_k127_2859971_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 342.0
CMS1_k127_2859971_1 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
CMS1_k127_2859971_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002217 173.0
CMS1_k127_2859971_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000006393 126.0
CMS1_k127_2859971_4 Methyltransferase type 11 - - - 0.0000000324 57.0
CMS1_k127_2874538_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.24e-200 628.0
CMS1_k127_2874538_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 481.0
CMS1_k127_2874538_2 molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 418.0
CMS1_k127_2874538_3 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
CMS1_k127_2874538_4 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001835 262.0
CMS1_k127_2874538_5 - - - - 0.00000000004249 72.0
CMS1_k127_2882748_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1119.0
CMS1_k127_2882748_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 514.0
CMS1_k127_2882748_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
CMS1_k127_2882748_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
CMS1_k127_2905664_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.415e-213 670.0
CMS1_k127_2905664_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.426e-197 619.0
CMS1_k127_2905664_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 561.0
CMS1_k127_2905664_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
CMS1_k127_2905664_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000003628 139.0
CMS1_k127_2940525_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 515.0
CMS1_k127_2940525_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 307.0
CMS1_k127_2940525_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000002164 247.0
CMS1_k127_2940525_3 DNA polymerase K02341 - 2.7.7.7 0.00000000000000000000000000009144 122.0
CMS1_k127_2940525_4 Murein transglycosylase K08305 - - 0.0000000000000000000000000001685 120.0
CMS1_k127_2943429_0 Aminotransferase K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 557.0
CMS1_k127_2943429_1 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
CMS1_k127_2943429_2 TupA-like ATPgrasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 317.0
CMS1_k127_2943429_3 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000002695 93.0
CMS1_k127_296011_0 TonB dependent receptor - - - 0.0 1020.0
CMS1_k127_296011_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 387.0
CMS1_k127_296011_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001925 239.0
CMS1_k127_296011_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000005613 225.0
CMS1_k127_296011_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000001519 151.0
CMS1_k127_2967067_0 COG1960 Acyl-CoA dehydrogenases - - - 1.08e-230 717.0
CMS1_k127_2967067_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
CMS1_k127_2967067_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 578.0
CMS1_k127_2967067_3 Glutathione S-transferase, C-terminal domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 486.0
CMS1_k127_2967067_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 338.0
CMS1_k127_2967067_5 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007146 293.0
CMS1_k127_2967067_6 Transcriptional regulator, TetR, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002086 261.0
CMS1_k127_2967067_7 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 243.0
CMS1_k127_2967067_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000000000002412 168.0
CMS1_k127_2999439_0 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 602.0
CMS1_k127_2999439_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 482.0
CMS1_k127_2999439_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000007551 123.0
CMS1_k127_2999439_11 Biotin-requiring enzyme K00658 - 2.3.1.61 0.000000000000000000000003718 104.0
CMS1_k127_2999439_2 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 471.0
CMS1_k127_2999439_3 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 419.0
CMS1_k127_2999439_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
CMS1_k127_2999439_5 Pyruvate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 384.0
CMS1_k127_2999439_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 345.0
CMS1_k127_2999439_7 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
CMS1_k127_2999439_8 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000006745 233.0
CMS1_k127_2999439_9 Thioesterase superfamily - - - 0.00000000000000000000000000000000007935 138.0
CMS1_k127_3041919_0 H gluconate symporter - - - 4.276e-208 655.0
CMS1_k127_3041919_1 Indoleamine 2,3-dioxygenase K00463 - 1.13.11.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 567.0
CMS1_k127_3041919_2 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 557.0
CMS1_k127_3041919_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 337.0
CMS1_k127_3041919_4 transcriptional - - - 0.00000000000000000000000000000000000000000000002818 176.0
CMS1_k127_3041919_5 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000000002518 170.0
CMS1_k127_3041919_6 Glycine zipper - - - 0.00000000000000000000000005226 113.0
CMS1_k127_3041919_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000007347 71.0
CMS1_k127_3048626_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 1.527e-277 871.0
CMS1_k127_3048626_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.364e-277 861.0
CMS1_k127_3048626_10 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000001776 181.0
CMS1_k127_3048626_11 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000002372 151.0
CMS1_k127_3048626_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000002355 117.0
CMS1_k127_3048626_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001845 90.0
CMS1_k127_3048626_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 485.0
CMS1_k127_3048626_3 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 479.0
CMS1_k127_3048626_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 359.0
CMS1_k127_3048626_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 331.0
CMS1_k127_3048626_6 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
CMS1_k127_3048626_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003805 279.0
CMS1_k127_3048626_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
CMS1_k127_3048626_9 Glyoxalase-like domain K04750 - - 0.000000000000000000000000000000000000000000000000000000000000000001586 231.0
CMS1_k127_3120419_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1130.0
CMS1_k127_3120419_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 535.0
CMS1_k127_3120419_2 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 473.0
CMS1_k127_3120419_3 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 362.0
CMS1_k127_3120419_4 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
CMS1_k127_3120419_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 326.0
CMS1_k127_3120419_6 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
CMS1_k127_3120419_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000007169 134.0
CMS1_k127_3170550_0 Major facilitator superfamily K08218 - - 3.786e-208 655.0
CMS1_k127_3170550_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 362.0
CMS1_k127_3170550_2 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000006108 253.0
CMS1_k127_3170550_3 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000000000002794 234.0
CMS1_k127_3241617_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 327.0
CMS1_k127_3241617_1 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 274.0
CMS1_k127_3241617_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000001646 144.0
CMS1_k127_3247305_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.32e-206 650.0
CMS1_k127_3247305_1 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 337.0
CMS1_k127_3247305_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 303.0
CMS1_k127_3247305_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000005368 257.0
CMS1_k127_3247305_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000897 170.0
CMS1_k127_3247305_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001539 149.0
CMS1_k127_3247305_6 protein conserved in bacteria K09985 - - 0.00000000000000000000000000000004973 126.0
CMS1_k127_3247305_7 - - - - 0.0000003329 55.0
CMS1_k127_3247305_8 - - - - 0.00004662 53.0
CMS1_k127_3252134_0 Von Willebrand factor A K09989 - - 3.231e-225 702.0
CMS1_k127_3252134_1 Protein of unknown function (DUF1343) - - - 1.796e-214 671.0
CMS1_k127_3252134_2 ATPase AAA - - - 0.000000000000000000000000000000000000000000000001236 174.0
CMS1_k127_3252134_3 - - - - 0.00000000000000000000000000000009049 126.0
CMS1_k127_3252134_4 - - - - 0.00000000000001759 73.0
CMS1_k127_3298572_0 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 5.565e-202 632.0
CMS1_k127_3298572_1 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 528.0
CMS1_k127_3298572_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 364.0
CMS1_k127_3298572_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 329.0
CMS1_k127_3298572_4 - - - - 0.0000000000000000000000000000001265 130.0
CMS1_k127_3298572_5 - - - - 0.000000000000000000000000001309 120.0
CMS1_k127_3298572_6 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000001704 76.0
CMS1_k127_3299253_0 Bacterial protein of unknown function (DUF885) - - - 9.933e-283 879.0
CMS1_k127_3299253_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 537.0
CMS1_k127_3299253_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 529.0
CMS1_k127_3299253_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 518.0
CMS1_k127_3299253_4 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 357.0
CMS1_k127_3299253_5 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000701 283.0
CMS1_k127_3299253_6 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
CMS1_k127_3299253_7 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000005171 217.0
CMS1_k127_3299253_8 - - - - 0.00000000005155 66.0
CMS1_k127_3308916_0 Dienelactone hydrolase family - - - 2.048e-258 811.0
CMS1_k127_3308916_1 component I K01665,K03342 - 2.6.1.85,4.1.3.38 4.342e-205 655.0
CMS1_k127_3308916_10 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000005067 149.0
CMS1_k127_3308916_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 475.0
CMS1_k127_3308916_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 417.0
CMS1_k127_3308916_4 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 410.0
CMS1_k127_3308916_5 General secretion pathway protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 298.0
CMS1_k127_3308916_6 Enoyl-CoA hydratase isomerase family protein K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000004114 232.0
CMS1_k127_3308916_7 glyoxalase - - - 0.000000000000000000000000000000000000000000000001013 176.0
CMS1_k127_3308916_8 Protein of unknown function (DUF4199) - - - 0.0000000000000000000000000000000000000000004327 163.0
CMS1_k127_3308916_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000002476 156.0
CMS1_k127_3330900_0 GTP-binding protein TypA K06207 - - 3.156e-319 985.0
CMS1_k127_3330900_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 1.271e-306 961.0
CMS1_k127_3330900_10 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000000000007792 149.0
CMS1_k127_3330900_11 - - - - 0.00000000000000000000000000004168 120.0
CMS1_k127_3330900_2 Toxic anion resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 432.0
CMS1_k127_3330900_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
CMS1_k127_3330900_4 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 323.0
CMS1_k127_3330900_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 320.0
CMS1_k127_3330900_6 Bile acid sodium symporter K14347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 326.0
CMS1_k127_3330900_7 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 307.0
CMS1_k127_3330900_8 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005533 247.0
CMS1_k127_3330900_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000886 220.0
CMS1_k127_3368187_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.293e-311 963.0
CMS1_k127_3368187_1 alginic acid biosynthetic process - - - 0.0000000000003896 73.0
CMS1_k127_3382172_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 341.0
CMS1_k127_3382172_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000001016 243.0
CMS1_k127_3382172_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000008798 198.0
CMS1_k127_3382172_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000009555 133.0
CMS1_k127_3382172_4 Domain of unknown function (DUF1971) - - - 0.0000000000000000000000000000001939 131.0
CMS1_k127_3382172_5 - - - - 0.000000000000009225 78.0
CMS1_k127_3387584_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007238 274.0
CMS1_k127_3387584_1 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000000000009543 174.0
CMS1_k127_3387584_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000001562 170.0
CMS1_k127_3387584_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000004145 95.0
CMS1_k127_3387584_4 Protein of unknown function (DUF1289) K06938 - - 0.000000000001993 68.0
CMS1_k127_3390053_0 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 9.529e-198 627.0
CMS1_k127_3390053_1 COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 580.0
CMS1_k127_3390053_10 Belongs to the ompA family - - - 0.0000000000004297 78.0
CMS1_k127_3390053_2 DNA-binding protein with the helix-hairpin-helix motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 491.0
CMS1_k127_3390053_3 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 495.0
CMS1_k127_3390053_4 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 492.0
CMS1_k127_3390053_5 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 342.0
CMS1_k127_3390053_6 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 322.0
CMS1_k127_3390053_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
CMS1_k127_3390053_8 ubiE/COQ5 methyltransferase family K13623 - - 0.000000000000000000000000000000000000000000000000000000000000000000002456 243.0
CMS1_k127_3390053_9 rRNA binding - - - 0.00000000000000000000000000000004859 134.0
CMS1_k127_3391001_0 of ABC transporters with duplicated ATPase K15738 - - 9.917e-282 875.0
CMS1_k127_3391001_1 D-amino acid aminotransferase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 338.0
CMS1_k127_3391001_2 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000001213 220.0
CMS1_k127_3391001_3 - - - - 0.0000000000000000000000000004871 116.0
CMS1_k127_3428216_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 390.0
CMS1_k127_3428216_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 352.0
CMS1_k127_3428216_2 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
CMS1_k127_3461700_0 Molydopterin dinucleotide binding domain - - - 8.892e-290 905.0
CMS1_k127_3461700_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 587.0
CMS1_k127_3461700_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 543.0
CMS1_k127_3461700_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 518.0
CMS1_k127_349395_0 TonB dependent receptor K02014 - - 1.672e-217 683.0
CMS1_k127_349395_1 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
CMS1_k127_349395_2 PRC-barrel domain - - - 0.0000000000000000000000000000000000000009857 164.0
CMS1_k127_349395_3 Protein of unknwon function (DUF3008) - - - 0.000000000000000000000328 97.0
CMS1_k127_349395_4 Peroxiredoxin - - - 0.00000111 51.0
CMS1_k127_3508030_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 421.0
CMS1_k127_3508030_1 with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 338.0
CMS1_k127_3508030_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000004014 228.0
CMS1_k127_3508030_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000006172 207.0
CMS1_k127_3508030_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000008246 172.0
CMS1_k127_3508030_5 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000002285 114.0
CMS1_k127_3609958_0 TonB-dependent receptor K02014 - - 6.97e-322 992.0
CMS1_k127_3609958_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009267 262.0
CMS1_k127_3609958_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000001295 165.0
CMS1_k127_361378_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 377.0
CMS1_k127_361378_1 conserved protein UCP033924 precursor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
CMS1_k127_361378_2 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 291.0
CMS1_k127_361378_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000003482 128.0
CMS1_k127_361378_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000005013 83.0
CMS1_k127_361378_5 - - - - 0.0000002358 59.0
CMS1_k127_3617438_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0 1017.0
CMS1_k127_3617438_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 564.0
CMS1_k127_3617438_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 374.0
CMS1_k127_3617438_3 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
CMS1_k127_3617438_4 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
CMS1_k127_3617438_5 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000787 233.0
CMS1_k127_3617438_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000008073 175.0
CMS1_k127_362021_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
CMS1_k127_362021_1 Domain of unknown function (DUF4915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 331.0
CMS1_k127_362021_2 - - - - 0.0000000000000000000000000000000000000000000000001276 186.0
CMS1_k127_3640886_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 506.0
CMS1_k127_3640886_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 318.0
CMS1_k127_3640886_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009412 263.0
CMS1_k127_3640886_3 Type II secretory pathway component PulC K02452 - - 0.0000000000000000000000000000000000000000000001049 175.0
CMS1_k127_3654088_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 519.0
CMS1_k127_3654088_1 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 500.0
CMS1_k127_3654088_10 SnoaL-like domain - - - 0.000000000000000000000000000000000000000005611 158.0
CMS1_k127_3654088_11 membrane - - - 0.000000000000002892 79.0
CMS1_k127_3654088_12 Domain of unknown function (DUF4167) - - - 0.0000000000007408 75.0
CMS1_k127_3654088_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 337.0
CMS1_k127_3654088_3 Aminomethyltransferase K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 322.0
CMS1_k127_3654088_4 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000577 273.0
CMS1_k127_3654088_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002018 265.0
CMS1_k127_3654088_6 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
CMS1_k127_3654088_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000001626 198.0
CMS1_k127_3654088_8 - - - - 0.00000000000000000000000000000000000000000000000000002542 197.0
CMS1_k127_3654088_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000004846 160.0
CMS1_k127_3672581_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1127.0
CMS1_k127_3672581_1 Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate K00812 - 2.6.1.1 7.176e-208 651.0
CMS1_k127_3672581_10 PhnA protein K06193 - - 0.00000000000000000000000000000000000000009344 156.0
CMS1_k127_3672581_11 Peptidase family M48 - - - 0.00000001981 60.0
CMS1_k127_3672581_2 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 351.0
CMS1_k127_3672581_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 318.0
CMS1_k127_3672581_4 O-acetylhomoserine K01738,K01740 - 2.5.1.47,2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 293.0
CMS1_k127_3672581_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003813 280.0
CMS1_k127_3672581_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006633 273.0
CMS1_k127_3672581_7 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
CMS1_k127_3672581_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000003229 235.0
CMS1_k127_3672581_9 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000000000000000000000000006903 215.0
CMS1_k127_3681693_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.285e-295 928.0
CMS1_k127_3681693_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 5.783e-203 642.0
CMS1_k127_3681693_2 peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 574.0
CMS1_k127_3681693_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
CMS1_k127_3681693_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000009017 220.0
CMS1_k127_3681693_5 DNA polymerase III K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000488 164.0
CMS1_k127_3693686_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 561.0
CMS1_k127_3693686_1 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000007939 117.0
CMS1_k127_3693686_2 - - - - 0.0000000000000000000001115 113.0
CMS1_k127_3734254_0 Adenylate cyclase - - - 6.634e-219 699.0
CMS1_k127_3734254_1 Peptidase, M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 588.0
CMS1_k127_3734254_10 EF-hand, calcium binding motif - - - 0.000000000000000000000000000000001113 138.0
CMS1_k127_3734254_11 response regulator - - - 0.0000000000000000000003344 102.0
CMS1_k127_3734254_12 SnoaL-like domain - - - 0.00000000000000002101 88.0
CMS1_k127_3734254_13 intracellular signal transduction - - - 0.00000000000009196 85.0
CMS1_k127_3734254_2 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 414.0
CMS1_k127_3734254_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
CMS1_k127_3734254_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 347.0
CMS1_k127_3734254_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 311.0
CMS1_k127_3734254_6 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003265 259.0
CMS1_k127_3734254_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002661 205.0
CMS1_k127_3734254_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000003148 176.0
CMS1_k127_3734254_9 - - - - 0.00000000000000000000000000000000007935 138.0
CMS1_k127_3762473_0 Polysaccharide biosynthesis protein - - - 1.829e-222 698.0
CMS1_k127_3762473_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 599.0
CMS1_k127_3762473_10 - - - - 0.000000000000000000000000072 115.0
CMS1_k127_3762473_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 509.0
CMS1_k127_3762473_3 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 492.0
CMS1_k127_3762473_4 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 443.0
CMS1_k127_3762473_5 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 426.0
CMS1_k127_3762473_6 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000244 224.0
CMS1_k127_3762473_7 conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000005861 210.0
CMS1_k127_3762473_8 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
CMS1_k127_3762473_9 protein involved in cysteine biosynthesis K06203 - - 0.00000000000000000000000000000000000000000000000000006119 194.0
CMS1_k127_3766942_0 of ABC transporters with duplicated ATPase K06158 - - 4.502e-286 889.0
CMS1_k127_3766942_1 Peptidase, M28 - - - 5.721e-263 820.0
CMS1_k127_3766942_10 succinate dehydrogenase K00242 - - 0.0000000000000000000000000000000000000000000000000000821 188.0
CMS1_k127_3766942_11 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000002215 180.0
CMS1_k127_3766942_12 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000002728 152.0
CMS1_k127_3766942_13 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.00002902 50.0
CMS1_k127_3766942_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.79e-214 670.0
CMS1_k127_3766942_3 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 452.0
CMS1_k127_3766942_4 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 408.0
CMS1_k127_3766942_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
CMS1_k127_3766942_6 ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
CMS1_k127_3766942_7 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 323.0
CMS1_k127_3766942_8 Spermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004199 278.0
CMS1_k127_3766942_9 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000000000000524 239.0
CMS1_k127_3824759_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1272.0
CMS1_k127_3824759_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 500.0
CMS1_k127_3824759_10 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 284.0
CMS1_k127_3824759_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000005912 250.0
CMS1_k127_3824759_12 Allophanate hydrolase subunit 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001907 261.0
CMS1_k127_3824759_13 LamB/YcsF family - - - 0.000000000000000000000000000000000000000000000000000000000004899 224.0
CMS1_k127_3824759_14 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000001747 192.0
CMS1_k127_3824759_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000004251 158.0
CMS1_k127_3824759_16 General secretion pathway protein K02459 - - 0.000000000000000000000000000000000000002711 153.0
CMS1_k127_3824759_17 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000000307 150.0
CMS1_k127_3824759_18 Outer membrane protein (OmpH-like) - - - 0.000000000000000000000000000000000000003666 154.0
CMS1_k127_3824759_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 500.0
CMS1_k127_3824759_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 400.0
CMS1_k127_3824759_4 COG1914 Mn2 and Fe2 transporters of the NRAMP family K03322 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 404.0
CMS1_k127_3824759_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 380.0
CMS1_k127_3824759_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
CMS1_k127_3824759_7 oxygenase K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 295.0
CMS1_k127_3824759_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 281.0
CMS1_k127_3824759_9 Type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
CMS1_k127_3834759_0 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 475.0
CMS1_k127_3834759_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 429.0
CMS1_k127_3834759_2 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 406.0
CMS1_k127_3834759_3 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 349.0
CMS1_k127_3834759_4 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000003003 251.0
CMS1_k127_3834759_5 2-vinyl bacteriochlorophyllide hydratase (BCHF) K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000000000001321 235.0
CMS1_k127_3834759_6 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
CMS1_k127_3854947_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1023.0
CMS1_k127_3854947_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 605.0
CMS1_k127_3854947_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 587.0
CMS1_k127_3854947_3 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001041 251.0
CMS1_k127_3854947_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000285 160.0
CMS1_k127_3854947_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000008936 87.0
CMS1_k127_3854947_6 Protein of unknown function (DUF2842) - - - 0.00000000000000002147 84.0
CMS1_k127_3858578_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 501.0
CMS1_k127_3858578_1 Lytic murein transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008691 276.0
CMS1_k127_3858578_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000005593 162.0
CMS1_k127_3858578_3 hydrolase (HAD superfamily) K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000003022 168.0
CMS1_k127_3858578_4 Resolvase, N terminal domain - - - 0.0000000007165 60.0
CMS1_k127_3929197_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.341e-200 627.0
CMS1_k127_3929197_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 477.0
CMS1_k127_3929197_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 322.0
CMS1_k127_3929197_3 Dicarboxylate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000004584 240.0
CMS1_k127_3932119_0 AFG1 family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 568.0
CMS1_k127_3932119_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 482.0
CMS1_k127_3932119_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 462.0
CMS1_k127_3932119_3 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001013 275.0
CMS1_k127_3932119_4 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000005685 154.0
CMS1_k127_3932119_5 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000001729 150.0
CMS1_k127_3938121_0 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 331.0
CMS1_k127_3938121_1 Formate/nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
CMS1_k127_3938121_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000001029 190.0
CMS1_k127_3938121_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000005685 179.0
CMS1_k127_3938121_12 - - - - 0.00000000000000000000000000000000000000000005318 170.0
CMS1_k127_3938121_13 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000001506 155.0
CMS1_k127_3938121_14 Phosphopantetheine attachment site - - - 0.000000000009442 73.0
CMS1_k127_3938121_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
CMS1_k127_3938121_3 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 288.0
CMS1_k127_3938121_4 protein conserved in bacteria K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003618 275.0
CMS1_k127_3938121_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 272.0
CMS1_k127_3938121_6 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 249.0
CMS1_k127_3938121_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000007845 213.0
CMS1_k127_3938121_8 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000000000001353 194.0
CMS1_k127_3938121_9 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000000000006493 179.0
CMS1_k127_3981345_0 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005445 248.0
CMS1_k127_3981345_1 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
CMS1_k127_3981345_2 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.000000000000000000000000000000000000000000000000000000007073 206.0
CMS1_k127_3981345_3 DNA repair protein MmcB-like - - - 0.00000000000000000000000000000000000000000000000002182 184.0
CMS1_k127_3981345_4 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000004713 156.0
CMS1_k127_3981345_5 Protein of unknown function (DUF1491) - - - 0.00000000000000000000000728 104.0
CMS1_k127_4006462_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.335e-204 648.0
CMS1_k127_4006462_1 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 421.0
CMS1_k127_4006462_2 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 347.0
CMS1_k127_4006462_3 Protein conserved in bacteria K11719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002726 264.0
CMS1_k127_4006462_4 Cold shock K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
CMS1_k127_4006462_5 protein conserved in bacteria K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000003236 227.0
CMS1_k127_4006462_6 membrane - - - 0.00000000000000000000000000000202 124.0
CMS1_k127_4006462_7 Trypsin-like serine protease - - - 0.000000000000134 72.0
CMS1_k127_4006462_8 Cold shock K03704 - - 0.00001622 51.0
CMS1_k127_4017880_0 DNA helicase K03654 - 3.6.4.12 3.007e-270 846.0
CMS1_k127_4017880_1 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase K06147 - - 3.075e-256 800.0
CMS1_k127_4017880_2 sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 455.0
CMS1_k127_4017880_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002442 200.0
CMS1_k127_4017880_4 Belongs to the GMC oxidoreductase family - - - 0.0000000000000000000000008327 107.0
CMS1_k127_40236_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.021e-228 728.0
CMS1_k127_40236_1 sugar transferase - - - 1.612e-209 659.0
CMS1_k127_40236_2 Transcriptional regulator K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 612.0
CMS1_k127_40236_3 Cysteine-rich domain K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 454.0
CMS1_k127_40236_4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 382.0
CMS1_k127_40236_5 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001619 266.0
CMS1_k127_4046418_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 358.0
CMS1_k127_4046418_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
CMS1_k127_4047776_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 557.0
CMS1_k127_4047776_1 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 505.0
CMS1_k127_4047776_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 320.0
CMS1_k127_4047776_3 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 293.0
CMS1_k127_4047776_4 - - - - 0.0000000000000004023 85.0
CMS1_k127_409157_0 DNA polymerase K02337 - 2.7.7.7 0.0 1509.0
CMS1_k127_409157_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K20034 - 6.2.1.44 4.313e-276 859.0
CMS1_k127_409157_2 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 3.042e-201 635.0
CMS1_k127_409157_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 330.0
CMS1_k127_409157_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002316 246.0
CMS1_k127_409157_5 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
CMS1_k127_409157_6 DNA repair photolyase - - - 0.000000000000000000000000000000000000000000000000000003684 193.0
CMS1_k127_4106413_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1151.0
CMS1_k127_4106413_1 TonB dependent receptor - - - 0.0 1008.0
CMS1_k127_4106413_10 Alpha beta - - - 0.0000000000000000000000000000000000000000000000000002543 195.0
CMS1_k127_4106413_11 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000007277 188.0
CMS1_k127_4106413_2 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 611.0
CMS1_k127_4106413_3 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 595.0
CMS1_k127_4106413_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 585.0
CMS1_k127_4106413_5 Citrate synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 397.0
CMS1_k127_4106413_6 helix_turn_helix isocitrate lyase regulation K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
CMS1_k127_4106413_7 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 328.0
CMS1_k127_4106413_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004159 269.0
CMS1_k127_4106413_9 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006378 271.0
CMS1_k127_4187187_0 DNA ligase K01971 - 6.5.1.1 0.0 1121.0
CMS1_k127_4187187_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 508.0
CMS1_k127_4187187_11 UPF0391 membrane protein - - - 0.000000000008049 69.0
CMS1_k127_4187187_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 500.0
CMS1_k127_4187187_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 407.0
CMS1_k127_4187187_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 361.0
CMS1_k127_4187187_5 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 304.0
CMS1_k127_4187187_6 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 290.0
CMS1_k127_4187187_7 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
CMS1_k127_4187187_8 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000000001512 203.0
CMS1_k127_4187187_9 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000006703 150.0
CMS1_k127_4195248_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000002894 216.0
CMS1_k127_4195248_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000002681 165.0
CMS1_k127_4195248_2 Protein of unknown function (DUF1702) K21161 - - 0.000000000000000000000000000000000000000251 162.0
CMS1_k127_4195248_3 - - - - 0.000003207 54.0
CMS1_k127_4206534_0 Malic enzyme K00029 - 1.1.1.40 0.0 1159.0
CMS1_k127_4206534_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.132e-249 779.0
CMS1_k127_4206534_2 Small protein A (tmRNA-binding) - - - 0.0000000000000000000000000000000000000000000000000000000004121 205.0
CMS1_k127_4206534_3 Ubiquinol-cytochrome C chaperone K17662 - - 0.000000000000000000000000000000000000000000000002241 181.0
CMS1_k127_4206534_4 Uncharacterized ACR, COG1399 - - - 0.00000000000000000000000000000000001276 143.0
CMS1_k127_4241530_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1029.0
CMS1_k127_4241530_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 3.259e-236 734.0
CMS1_k127_4241530_2 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 428.0
CMS1_k127_4241530_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 338.0
CMS1_k127_4241530_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000797 237.0
CMS1_k127_4241530_5 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000336 193.0
CMS1_k127_4260584_0 Acyl-CoA dehydrogenase, middle domain - - - 1.124e-197 622.0
CMS1_k127_4260584_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 565.0
CMS1_k127_4260584_2 COG2211 Na melibiose symporter and related transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 569.0
CMS1_k127_4260584_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 368.0
CMS1_k127_4260584_4 - - - - 0.00000003208 59.0
CMS1_k127_4260584_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000002234 52.0
CMS1_k127_43466_0 Alkyl sulfatase dimerisation - - - 9.93e-263 826.0
CMS1_k127_43466_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 423.0
CMS1_k127_43466_2 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 353.0
CMS1_k127_43466_3 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000003577 171.0
CMS1_k127_43466_4 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000000000000000002242 131.0
CMS1_k127_43466_5 general secretion pathway protein K02457 - - 0.000000000000000000000000000007239 124.0
CMS1_k127_4376348_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1133.0
CMS1_k127_4376348_1 Ceramidase - - - 0.0000000000000000000000000000000000000002774 159.0
CMS1_k127_4376348_2 - - - - 0.00007439 46.0
CMS1_k127_4409656_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 385.0
CMS1_k127_4409656_1 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 306.0
CMS1_k127_4409656_2 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 292.0
CMS1_k127_4409656_3 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
CMS1_k127_4409656_4 energy transducer activity - - - 0.00000000000000000000000000000000000000000000000000000001764 210.0
CMS1_k127_4409656_5 Helix-turn-helix - - - 0.0000000000000000000000000000000002202 138.0
CMS1_k127_4499356_0 Citrate transporter - - - 2.858e-220 698.0
CMS1_k127_4499356_1 Cupin superfamily protein K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 488.0
CMS1_k127_4499356_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 399.0
CMS1_k127_4499356_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001136 240.0
CMS1_k127_4499356_4 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000000000000007432 208.0
CMS1_k127_4499356_5 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000009402 206.0
CMS1_k127_4499356_6 Ion channel - - - 0.00000000000000000000000000000000001236 139.0
CMS1_k127_4499356_7 Cold-shock protein K03704 - - 0.000000000000000000000000000007043 119.0
CMS1_k127_4499356_8 UPF0391 membrane protein - - - 0.000000003884 65.0
CMS1_k127_45104_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 5.001e-242 764.0
CMS1_k127_45104_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 607.0
CMS1_k127_45104_2 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 352.0
CMS1_k127_45104_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008962 332.0
CMS1_k127_45104_4 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000001085 219.0
CMS1_k127_45104_5 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000000000000000000000000003248 157.0
CMS1_k127_4530851_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 8.4e-323 1011.0
CMS1_k127_4530851_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 607.0
CMS1_k127_4530851_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004736 262.0
CMS1_k127_4530851_3 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000004242 194.0
CMS1_k127_4530851_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000003489 165.0
CMS1_k127_4546564_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 466.0
CMS1_k127_4546564_1 NADPH quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 462.0
CMS1_k127_4546564_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 454.0
CMS1_k127_4546564_3 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 432.0
CMS1_k127_4546564_4 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 336.0
CMS1_k127_4546564_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001318 231.0
CMS1_k127_4546564_6 belongs to the nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000003547 156.0
CMS1_k127_4546564_7 Protein of unknown function (DUF1192) - - - 0.000000000000000115 82.0
CMS1_k127_4551438_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.042e-226 715.0
CMS1_k127_4551438_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 577.0
CMS1_k127_4551438_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 323.0
CMS1_k127_4574933_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 5.551e-248 771.0
CMS1_k127_4574933_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 549.0
CMS1_k127_4574933_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 517.0
CMS1_k127_4574933_3 Branched-chain amino acid aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 338.0
CMS1_k127_4574933_4 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 331.0
CMS1_k127_4574933_5 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000006627 206.0
CMS1_k127_4574933_6 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
CMS1_k127_4574933_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000001005 151.0
CMS1_k127_4574933_8 acyl-CoA thioester hydrolase K10806 - - 0.00000000000000000000000000000034 128.0
CMS1_k127_4582209_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1539.0
CMS1_k127_4582209_1 glutamate dehydrogenase K15371 - 1.4.1.2 1.821e-244 768.0
CMS1_k127_4582209_10 Transglycosylase associated protein - - - 0.00000000000000000000000000000006909 126.0
CMS1_k127_4582209_11 - - - - 0.000000000000000000000000003042 115.0
CMS1_k127_4582209_12 molecular chaperone - - - 0.000000000000001536 76.0
CMS1_k127_4582209_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 590.0
CMS1_k127_4582209_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 511.0
CMS1_k127_4582209_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 445.0
CMS1_k127_4582209_5 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 422.0
CMS1_k127_4582209_6 PhzC PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 361.0
CMS1_k127_4582209_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 316.0
CMS1_k127_4582209_8 Protein of unknown function (DUF1153) - - - 0.000000000000000000000000000000000000000000000000000001431 192.0
CMS1_k127_4582209_9 Domain of unknown function (DUF4281) - - - 0.000000000000000000000000000000000000002607 153.0
CMS1_k127_4598216_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1880.0
CMS1_k127_4598216_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 424.0
CMS1_k127_4611919_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1118.0
CMS1_k127_4611919_1 transport - - - 5.805e-228 733.0
CMS1_k127_4611919_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000006721 202.0
CMS1_k127_4611919_11 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000002173 190.0
CMS1_k127_4611919_12 receptor - - - 0.00000000000000000000000000000000000000105 156.0
CMS1_k127_4611919_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000031 140.0
CMS1_k127_4611919_14 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000003165 130.0
CMS1_k127_4611919_15 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.0000000000000000001198 99.0
CMS1_k127_4611919_2 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 387.0
CMS1_k127_4611919_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 355.0
CMS1_k127_4611919_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 323.0
CMS1_k127_4611919_5 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 314.0
CMS1_k127_4611919_6 ribonuclease E activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002421 264.0
CMS1_k127_4611919_7 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001366 252.0
CMS1_k127_4611919_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000007509 224.0
CMS1_k127_4611919_9 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000001001 218.0
CMS1_k127_4648028_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.124e-259 807.0
CMS1_k127_4648028_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 456.0
CMS1_k127_4648028_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 437.0
CMS1_k127_4648028_3 XRE family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
CMS1_k127_4648028_4 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000001097 139.0
CMS1_k127_4648028_5 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000003343 135.0
CMS1_k127_4648028_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000003465 132.0
CMS1_k127_4648028_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000002164 115.0
CMS1_k127_4662799_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 533.0
CMS1_k127_4662799_1 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 468.0
CMS1_k127_4662799_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 440.0
CMS1_k127_4662799_3 Belongs to the HesB IscA family - - - 0.00000000000000000000000000000000000000000002619 164.0
CMS1_k127_4662799_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000003621 69.0
CMS1_k127_4662799_5 YjgP YjgQ family K11720 - - 0.0000000002562 60.0
CMS1_k127_4665980_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1345.0
CMS1_k127_4665980_1 Asparagine synthase K01953 - 6.3.5.4 3.744e-310 959.0
CMS1_k127_4665980_10 DNA recombination protein K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
CMS1_k127_4665980_11 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 335.0
CMS1_k127_4665980_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
CMS1_k127_4665980_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 514.0
CMS1_k127_4665980_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 488.0
CMS1_k127_4665980_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 449.0
CMS1_k127_4665980_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 425.0
CMS1_k127_4665980_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 394.0
CMS1_k127_4665980_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 395.0
CMS1_k127_4665980_8 Type II secretory pathway, component ExeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 397.0
CMS1_k127_4665980_9 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 393.0
CMS1_k127_4667437_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1075.0
CMS1_k127_4667437_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 419.0
CMS1_k127_4667437_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 391.0
CMS1_k127_4667437_3 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 368.0
CMS1_k127_4667437_4 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 368.0
CMS1_k127_4667437_5 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 331.0
CMS1_k127_4667437_6 protein affecting Mg2 Co2 transport K06195 - - 0.000000000000000000000000000000000000000000000000000002036 193.0
CMS1_k127_4667437_7 DNA-binding protein K11940 - - 0.000000000000000000000000000000000000000000000001112 176.0
CMS1_k127_4678516_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 589.0
CMS1_k127_4678516_1 inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 330.0
CMS1_k127_4678516_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000001989 50.0
CMS1_k127_4682153_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.214e-250 775.0
CMS1_k127_4682153_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 523.0
CMS1_k127_4682153_10 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000003334 149.0
CMS1_k127_4682153_11 Thioesterase superfamily - - - 0.000000000000000000000000000000002619 130.0
CMS1_k127_4682153_12 Antibiotic biosynthesis monooxygenase - - - 0.0002405 44.0
CMS1_k127_4682153_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
CMS1_k127_4682153_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
CMS1_k127_4682153_4 membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
CMS1_k127_4682153_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 309.0
CMS1_k127_4682153_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
CMS1_k127_4682153_7 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 248.0
CMS1_k127_4682153_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
CMS1_k127_4682153_9 membrane K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
CMS1_k127_4686255_0 cytochrome C K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 436.0
CMS1_k127_4686255_1 Alkyl hydroperoxide reductase K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 232.0
CMS1_k127_4686255_2 Cytochrome c biogenesis factor K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000006778 227.0
CMS1_k127_4686255_3 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000001632 181.0
CMS1_k127_4693521_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.369e-195 615.0
CMS1_k127_4693521_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 461.0
CMS1_k127_4693521_10 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000111 110.0
CMS1_k127_4693521_11 Pilus assembly protein PilZ - - - 0.00000000000000000000004537 104.0
CMS1_k127_4693521_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000002845 92.0
CMS1_k127_4693521_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 428.0
CMS1_k127_4693521_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 290.0
CMS1_k127_4693521_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000001779 234.0
CMS1_k127_4693521_5 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000004038 193.0
CMS1_k127_4693521_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000003665 185.0
CMS1_k127_4693521_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000423 176.0
CMS1_k127_4693521_8 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000000001665 162.0
CMS1_k127_4693521_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000002519 136.0
CMS1_k127_4694039_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.436e-198 623.0
CMS1_k127_4694039_1 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 602.0
CMS1_k127_4694039_11 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000007347 71.0
CMS1_k127_4694039_2 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 555.0
CMS1_k127_4694039_3 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 463.0
CMS1_k127_4694039_4 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
CMS1_k127_4694039_5 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 357.0
CMS1_k127_4694039_6 Siroheme synthase K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
CMS1_k127_4694039_7 - - - - 0.000000000000000000000000000000000000006654 151.0
CMS1_k127_4694039_8 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000006644 128.0
CMS1_k127_4694039_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000002412 116.0
CMS1_k127_4719674_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.638e-207 656.0
CMS1_k127_4719674_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 577.0
CMS1_k127_4719674_2 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 502.0
CMS1_k127_4719674_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 449.0
CMS1_k127_4719674_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 424.0
CMS1_k127_4719674_5 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 312.0
CMS1_k127_4719674_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001196 223.0
CMS1_k127_4745068_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.604e-220 693.0
CMS1_k127_4745068_1 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
CMS1_k127_4745068_2 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000004209 150.0
CMS1_k127_4745068_3 - - - - 0.0002263 45.0
CMS1_k127_4772970_0 domain, Protein - - - 3.416e-308 969.0
CMS1_k127_4772970_1 AraC-binding-like domain - - - 0.0000000000000000005193 98.0
CMS1_k127_4772970_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000007295 84.0
CMS1_k127_4772970_3 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000008711 66.0
CMS1_k127_4781445_0 glutamate--cysteine ligase K01919 - 6.3.2.2 1.331e-255 792.0
CMS1_k127_4781445_1 receptor K02014 - - 3.786e-254 805.0
CMS1_k127_4781445_10 DedA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 310.0
CMS1_k127_4781445_11 aspartate racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 306.0
CMS1_k127_4781445_12 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000001265 166.0
CMS1_k127_4781445_13 nad(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000001375 163.0
CMS1_k127_4781445_14 Protein of unknown function (DUF2855) - - - 0.00000000006164 65.0
CMS1_k127_4781445_2 alanine symporter K03310 - - 2.113e-247 772.0
CMS1_k127_4781445_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.067e-244 767.0
CMS1_k127_4781445_4 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 581.0
CMS1_k127_4781445_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 493.0
CMS1_k127_4781445_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 493.0
CMS1_k127_4781445_7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 473.0
CMS1_k127_4781445_8 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 395.0
CMS1_k127_4781445_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
CMS1_k127_4814125_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 7.436e-232 722.0
CMS1_k127_4814125_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.712e-208 658.0
CMS1_k127_4814125_10 N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001078 216.0
CMS1_k127_4814125_11 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000002469 194.0
CMS1_k127_4814125_12 - - - - 0.0000000000000000000000000000000007607 139.0
CMS1_k127_4814125_13 - - - - 0.00001098 48.0
CMS1_k127_4814125_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 627.0
CMS1_k127_4814125_3 coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 454.0
CMS1_k127_4814125_4 Cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 411.0
CMS1_k127_4814125_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 403.0
CMS1_k127_4814125_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
CMS1_k127_4814125_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 313.0
CMS1_k127_4814125_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 307.0
CMS1_k127_4814125_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000004765 212.0
CMS1_k127_4819502_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 615.0
CMS1_k127_4819502_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 526.0
CMS1_k127_4819502_2 DEAD DEAH box helicase K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 504.0
CMS1_k127_4819502_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 479.0
CMS1_k127_4819502_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
CMS1_k127_4819502_5 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 330.0
CMS1_k127_4819502_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000003735 263.0
CMS1_k127_4819502_7 sugar transferase K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000005977 241.0
CMS1_k127_4819502_8 GtrA-like protein - - - 0.00000000000000000000000003822 113.0
CMS1_k127_483318_0 Histidine kinase - - - 4.697e-209 659.0
CMS1_k127_483318_1 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 611.0
CMS1_k127_483318_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000003222 190.0
CMS1_k127_483318_11 chorismate mutase K04092 - 5.4.99.5 0.000000000000000000000000000000000000000001098 157.0
CMS1_k127_483318_12 ETC complex I subunit - - - 0.00000000000000000000000000000000000000003562 153.0
CMS1_k127_483318_13 - - - - 0.0000000000000000000000001099 107.0
CMS1_k127_483318_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 572.0
CMS1_k127_483318_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 525.0
CMS1_k127_483318_4 arginine N-succinyltransferase K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 487.0
CMS1_k127_483318_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
CMS1_k127_483318_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 288.0
CMS1_k127_483318_7 Methanol dehydrogenase K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 290.0
CMS1_k127_483318_8 membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007385 249.0
CMS1_k127_483318_9 Nudix hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000238 243.0
CMS1_k127_4837821_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0 1058.0
CMS1_k127_4837821_1 P-type ATPase K01533 - 3.6.3.4 4.101e-261 823.0
CMS1_k127_4837821_10 secretion activating protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000362 262.0
CMS1_k127_4837821_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005923 253.0
CMS1_k127_4837821_12 part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000002002 239.0
CMS1_k127_4837821_13 Holin of 3TMs, for gene-transfer release - - - 0.000000000000000000000000000000000000000000000000000000000000000008946 226.0
CMS1_k127_4837821_14 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
CMS1_k127_4837821_15 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
CMS1_k127_4837821_16 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000004043 165.0
CMS1_k127_4837821_17 - - - - 0.0000000000000000000000000000000000000685 150.0
CMS1_k127_4837821_18 Integral membrane protein linked to a cation - - - 0.0000000000000000000000000000000000005549 145.0
CMS1_k127_4837821_19 - - - - 0.0000000000000000000000000000000001001 139.0
CMS1_k127_4837821_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 569.0
CMS1_k127_4837821_20 - - - - 0.00000000000000000000000001746 118.0
CMS1_k127_4837821_21 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000003796 75.0
CMS1_k127_4837821_22 helix_turn_helix, Lux Regulon - - - 0.000000000001416 74.0
CMS1_k127_4837821_3 sulfate adenylyltransferase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 544.0
CMS1_k127_4837821_4 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 520.0
CMS1_k127_4837821_5 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 464.0
CMS1_k127_4837821_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 432.0
CMS1_k127_4837821_7 Nitrogen fixation protein fixG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 384.0
CMS1_k127_4837821_8 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 364.0
CMS1_k127_4837821_9 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001864 269.0
CMS1_k127_4845356_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 3.735e-314 986.0
CMS1_k127_4845356_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000211 214.0
CMS1_k127_4854256_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.338e-226 707.0
CMS1_k127_4854256_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 536.0
CMS1_k127_4854256_2 permease K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 402.0
CMS1_k127_4854256_3 transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 337.0
CMS1_k127_4854256_4 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000002484 109.0
CMS1_k127_4854256_5 DNA polymerase alpha chain like domain - - - 0.00000000000000000002101 93.0
CMS1_k127_4867392_0 Acts as a magnesium transporter K06213 - - 2.081e-197 625.0
CMS1_k127_4867392_1 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 467.0
CMS1_k127_4867392_10 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000000000000000000000006126 204.0
CMS1_k127_4867392_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003712 183.0
CMS1_k127_4867392_12 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000005842 145.0
CMS1_k127_4867392_13 - - - - 0.0000000000000000001348 94.0
CMS1_k127_4867392_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 446.0
CMS1_k127_4867392_3 glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 396.0
CMS1_k127_4867392_4 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 371.0
CMS1_k127_4867392_5 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
CMS1_k127_4867392_6 Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 288.0
CMS1_k127_4867392_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008646 248.0
CMS1_k127_4867392_8 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
CMS1_k127_4867392_9 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000000000000000000000000000000001965 221.0
CMS1_k127_487083_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 301.0
CMS1_k127_487083_1 - - - - 0.0000000000000000000000000000000001504 135.0
CMS1_k127_4883658_0 Protein of unknown function (DUF3376) - - - 8.334e-265 831.0
CMS1_k127_4883658_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.519e-222 694.0
CMS1_k127_4883658_10 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000000000002106 190.0
CMS1_k127_4883658_11 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000003885 165.0
CMS1_k127_4883658_12 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000000000001021 143.0
CMS1_k127_4883658_13 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000000000001531 74.0
CMS1_k127_4883658_14 Flp/Fap pilin component K02651 - - 0.00000000116 61.0
CMS1_k127_4883658_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 9.202e-218 690.0
CMS1_k127_4883658_3 peptidase M48, Ste24p - - - 6.155e-194 616.0
CMS1_k127_4883658_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 525.0
CMS1_k127_4883658_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 478.0
CMS1_k127_4883658_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 472.0
CMS1_k127_4883658_7 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 357.0
CMS1_k127_4883658_8 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
CMS1_k127_4883658_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000001202 238.0
CMS1_k127_4886888_0 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 591.0
CMS1_k127_4886888_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 454.0
CMS1_k127_4886888_2 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K11740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 451.0
CMS1_k127_4886888_3 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
CMS1_k127_4886888_4 - - - - 0.0000000000000000000000000000000001977 146.0
CMS1_k127_4886888_5 - - - - 0.0000000000000000000001076 103.0
CMS1_k127_4890825_0 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 1e-323 1004.0
CMS1_k127_4890825_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.129e-276 858.0
CMS1_k127_4890825_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 489.0
CMS1_k127_4890825_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000004152 211.0
CMS1_k127_4890825_4 protein conserved in bacteria - - - 0.00000000000000000000000001929 119.0
CMS1_k127_4890825_5 Domain of unknown function (DUF4402) - - - 0.000000000000004977 82.0
CMS1_k127_4890825_6 peptidase U62, modulator of DNA gyrase K03568 - - 0.00000000000861 66.0
CMS1_k127_4890825_7 Domain of unknown function (DUF4402) - - - 0.0000000002483 68.0
CMS1_k127_4890825_8 Domain of unknown function (DUF4402) - - - 0.00000003202 62.0
CMS1_k127_4910548_0 pyridine nucleotide-disulfide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 449.0
CMS1_k127_4910548_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 419.0
CMS1_k127_4910548_10 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
CMS1_k127_4910548_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000001331 200.0
CMS1_k127_4910548_12 - - - - 0.00000000000000000000000000001359 123.0
CMS1_k127_4910548_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 420.0
CMS1_k127_4910548_3 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
CMS1_k127_4910548_4 Peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 311.0
CMS1_k127_4910548_5 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
CMS1_k127_4910548_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
CMS1_k127_4910548_7 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005681 268.0
CMS1_k127_4910548_8 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001899 261.0
CMS1_k127_4910548_9 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000072 251.0
CMS1_k127_4922623_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1076.0
CMS1_k127_4922623_1 Extracellular solute-binding protein - - - 1.941e-205 651.0
CMS1_k127_4922623_2 General secretion pathway protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 405.0
CMS1_k127_4922623_3 Tetratricopeptide repeat - - - 0.000000000000000000002146 97.0
CMS1_k127_4940118_0 usher protein - - - 2.097e-291 923.0
CMS1_k127_4940118_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
CMS1_k127_4940118_2 COG3121 P pilus assembly protein, chaperone PapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 316.0
CMS1_k127_4940118_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000366 252.0
CMS1_k127_4940118_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000007138 174.0
CMS1_k127_4940118_5 Domain of unknown function (DUF4402) - - - 0.00000000000000000000000000008669 121.0
CMS1_k127_4942613_0 Histidine kinase K13587 - 2.7.13.3 2.294e-291 915.0
CMS1_k127_4942613_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 4.794e-220 702.0
CMS1_k127_4942613_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 2.441e-194 610.0
CMS1_k127_4942613_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 436.0
CMS1_k127_4942613_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
CMS1_k127_4942613_5 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
CMS1_k127_4942613_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000002607 145.0
CMS1_k127_4942613_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000005833 145.0
CMS1_k127_4952458_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 471.0
CMS1_k127_4952458_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 323.0
CMS1_k127_4952458_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000009019 205.0
CMS1_k127_4952458_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000197 126.0
CMS1_k127_4952458_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000006148 103.0
CMS1_k127_4952458_5 - - - - 0.0000000000001523 74.0
CMS1_k127_495400_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1654.0
CMS1_k127_495400_1 Cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
CMS1_k127_495400_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003955 231.0
CMS1_k127_495400_4 Domain of unknown function (DUF4345) - - - 0.000000000000000008577 87.0
CMS1_k127_4963712_0 Dehydrogenase K17760 - 1.1.9.1 0.0 1019.0
CMS1_k127_4963712_1 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 4.379e-278 857.0
CMS1_k127_4963712_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 469.0
CMS1_k127_4963712_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003778 254.0
CMS1_k127_4963712_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000001263 211.0
CMS1_k127_4963712_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001221 209.0
CMS1_k127_4998505_0 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 521.0
CMS1_k127_4998505_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 412.0
CMS1_k127_4998505_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 349.0
CMS1_k127_4998505_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 337.0
CMS1_k127_4998505_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
CMS1_k127_4998505_5 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006724 247.0
CMS1_k127_4998505_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
CMS1_k127_4998505_7 PspA/IM30 family - - - 0.00000000000000861 83.0
CMS1_k127_502416_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 8.066e-246 767.0
CMS1_k127_502416_1 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 351.0
CMS1_k127_502416_2 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 307.0
CMS1_k127_502416_3 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003845 210.0
CMS1_k127_502416_4 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000008084 169.0
CMS1_k127_502416_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000002381 117.0
CMS1_k127_502416_6 TonB dependent receptor K16090 - - 0.00000000000000000000000006582 108.0
CMS1_k127_5035262_0 His Kinase A (phosphoacceptor) domain - - - 4.23e-301 967.0
CMS1_k127_5035262_1 Polysaccharide deacetylase - - - 1.994e-226 709.0
CMS1_k127_5035262_2 Beta-lactamase - - - 7.694e-199 632.0
CMS1_k127_5035262_3 - - - - 2.755e-194 614.0
CMS1_k127_5035262_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 433.0
CMS1_k127_5035262_5 E-Z type HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 343.0
CMS1_k127_5035262_6 Transcriptional regulator, gntR family K11475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
CMS1_k127_5035262_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
CMS1_k127_5035262_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 319.0
CMS1_k127_5035262_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001817 158.0
CMS1_k127_5041027_0 nucleoside K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 518.0
CMS1_k127_5041027_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 283.0
CMS1_k127_5041027_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
CMS1_k127_5057627_0 DNA repair photolyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 481.0
CMS1_k127_5057627_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 282.0
CMS1_k127_5057627_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000296 181.0
CMS1_k127_5057627_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K20034 - 6.2.1.44 0.0000000000000000005432 86.0
CMS1_k127_5058344_0 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
CMS1_k127_5058344_1 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 379.0
CMS1_k127_5058344_2 to the N-terminal domain of Lon protease K07157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 297.0
CMS1_k127_5058344_3 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
CMS1_k127_5058344_4 - - - - 0.0000000000000000000000002839 111.0
CMS1_k127_5058344_5 Belongs to the UPF0434 family K09791 - - 0.000000000000000034 82.0
CMS1_k127_5058344_6 Protein of unknown function (DUF4019) - - - 0.00000000002873 72.0
CMS1_k127_5058344_8 - - - - 0.00003847 54.0
CMS1_k127_5062341_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.735e-273 850.0
CMS1_k127_5062341_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.386e-201 637.0
CMS1_k127_5062341_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 582.0
CMS1_k127_5062341_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 503.0
CMS1_k127_5062341_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 418.0
CMS1_k127_5062341_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 371.0
CMS1_k127_5062341_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000001052 196.0
CMS1_k127_5062341_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000000009082 127.0
CMS1_k127_5098827_0 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 344.0
CMS1_k127_5098827_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
CMS1_k127_5098827_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001294 167.0
CMS1_k127_5098827_3 - - - - 0.00000000000000000002448 96.0
CMS1_k127_5098827_4 membrane protein, TerC - - - 0.0000000000001126 71.0
CMS1_k127_5099941_0 RmlD substrate binding domain K21271,K22320 - 1.1.1.394,1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
CMS1_k127_5099941_1 Flavin containing amine oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005229 259.0
CMS1_k127_5099941_2 Protein of unknown function (DUF3429) - - - 0.00000000000000000000000000000000000005621 153.0
CMS1_k127_5121669_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.411e-241 753.0
CMS1_k127_5121669_1 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 566.0
CMS1_k127_5121669_2 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 336.0
CMS1_k127_5121669_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000005042 233.0
CMS1_k127_5121669_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000003746 182.0
CMS1_k127_5121669_5 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000003779 156.0
CMS1_k127_5121669_6 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000001677 111.0
CMS1_k127_5134387_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1089.0
CMS1_k127_5134387_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
CMS1_k127_5134387_10 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K11159 - - 0.0000000000000000000000000000000001646 140.0
CMS1_k127_5134387_11 Carboxylesterase family - - - 0.00000000000001733 76.0
CMS1_k127_5134387_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 485.0
CMS1_k127_5134387_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 434.0
CMS1_k127_5134387_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007209 269.0
CMS1_k127_5134387_5 Hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
CMS1_k127_5134387_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001022 263.0
CMS1_k127_5134387_7 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009568 262.0
CMS1_k127_5134387_8 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
CMS1_k127_5134387_9 MerC mercury resistance protein - - - 0.0000000000000000000000000000000000000001896 153.0
CMS1_k127_5199273_0 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K21822 - 1.13.11.82 2.123e-232 726.0
CMS1_k127_5199273_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 594.0
CMS1_k127_5199273_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000003117 186.0
CMS1_k127_5199273_3 WHG domain - - - 0.000000000000000000000000000000000000000000000000003636 188.0
CMS1_k127_5235837_0 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 570.0
CMS1_k127_5235837_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004187 244.0
CMS1_k127_5235837_2 FecR protein - - - 0.00000000000000000000000000000000000000000000125 178.0
CMS1_k127_5246493_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.151e-244 763.0
CMS1_k127_5246493_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.368e-228 720.0
CMS1_k127_5246493_2 synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000001423 213.0
CMS1_k127_5246493_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000001216 122.0
CMS1_k127_5259637_0 signal peptide peptidase K04773 - - 5.852e-203 650.0
CMS1_k127_5259637_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
CMS1_k127_5259637_2 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
CMS1_k127_5259637_3 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000000000000000636 182.0
CMS1_k127_5259637_4 DoxX K15977 - - 0.000000000000000000000000000000000000000003355 159.0
CMS1_k127_5284900_0 TonB-dependent receptor plug - - - 1.779e-304 952.0
CMS1_k127_5284900_1 Belongs to the glutamate synthase family - - - 2.268e-237 747.0
CMS1_k127_5284900_10 transcriptional K05800 - - 0.000000000000000000000000000000000000000000000000000000000001343 212.0
CMS1_k127_5284900_11 Beta-lactamase - - - 0.00000000000000000000000000000000000000000004474 166.0
CMS1_k127_5284900_2 Beta-lactamase class C - - - 2.695e-231 727.0
CMS1_k127_5284900_3 amino acid peptide transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 584.0
CMS1_k127_5284900_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 542.0
CMS1_k127_5284900_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 529.0
CMS1_k127_5284900_6 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 475.0
CMS1_k127_5284900_7 Mandelate racemase muconate lactonizing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 445.0
CMS1_k127_5284900_8 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 420.0
CMS1_k127_5284900_9 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 340.0
CMS1_k127_5330817_0 Beta-lactamase - - - 6.601e-289 900.0
CMS1_k127_5330817_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.066e-211 664.0
CMS1_k127_5330817_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 612.0
CMS1_k127_5330817_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 546.0
CMS1_k127_5330817_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 535.0
CMS1_k127_5330817_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 510.0
CMS1_k127_5330817_6 enoyl-CoA hydratase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 400.0
CMS1_k127_5330817_7 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 378.0
CMS1_k127_5330817_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000001766 216.0
CMS1_k127_5332420_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1460.0
CMS1_k127_5332420_1 TonB dependent receptor - - - 0.0 1278.0
CMS1_k127_5332420_10 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 417.0
CMS1_k127_5332420_11 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
CMS1_k127_5332420_12 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
CMS1_k127_5332420_13 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 312.0
CMS1_k127_5332420_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
CMS1_k127_5332420_15 Acetyltransferase (GNAT) domain K03829 - - 0.0000000000000000000000000000000000000000000000000000000006752 204.0
CMS1_k127_5332420_16 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000003342 185.0
CMS1_k127_5332420_17 Protein of unknown function (DUF2849) - - - 0.000000000000000000000000000000000000000000000002204 176.0
CMS1_k127_5332420_18 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000004971 165.0
CMS1_k127_5332420_2 Sulfite reductase K00381 - 1.8.1.2 2.095e-306 944.0
CMS1_k127_5332420_20 Resolvase - - - 0.00000000005582 63.0
CMS1_k127_5332420_3 2-nitropropane dioxygenase - - - 6.209e-266 822.0
CMS1_k127_5332420_4 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 7.975e-217 681.0
CMS1_k127_5332420_5 Ammonium Transporter K03320 - - 3.261e-194 614.0
CMS1_k127_5332420_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 573.0
CMS1_k127_5332420_7 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 576.0
CMS1_k127_5332420_8 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 497.0
CMS1_k127_5332420_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 484.0
CMS1_k127_5386846_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1035.0
CMS1_k127_5386846_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.798e-291 899.0
CMS1_k127_5386846_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 399.0
CMS1_k127_5386846_11 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 344.0
CMS1_k127_5386846_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 333.0
CMS1_k127_5386846_13 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003348 248.0
CMS1_k127_5386846_14 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009466 233.0
CMS1_k127_5386846_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000001648 228.0
CMS1_k127_5386846_16 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000009369 214.0
CMS1_k127_5386846_17 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000001658 215.0
CMS1_k127_5386846_18 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000000006077 177.0
CMS1_k127_5386846_19 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000003475 168.0
CMS1_k127_5386846_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.04e-280 865.0
CMS1_k127_5386846_20 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000003484 143.0
CMS1_k127_5386846_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 - - 0.00000000000000000000000000000001293 128.0
CMS1_k127_5386846_22 Protein of unknown function (DUF2490) - - - 0.0000000000000000002798 96.0
CMS1_k127_5386846_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 577.0
CMS1_k127_5386846_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 517.0
CMS1_k127_5386846_5 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 512.0
CMS1_k127_5386846_6 Metal binding domain of Ada K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 461.0
CMS1_k127_5386846_7 Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 457.0
CMS1_k127_5386846_8 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 409.0
CMS1_k127_5386846_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 404.0
CMS1_k127_5388849_0 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 520.0
CMS1_k127_5388849_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 471.0
CMS1_k127_5388849_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000002355 132.0
CMS1_k127_5388849_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000001984 76.0
CMS1_k127_5390881_0 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 355.0
CMS1_k127_5390881_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008576 261.0
CMS1_k127_5390881_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000002394 207.0
CMS1_k127_539780_0 Belongs to the DEAD box helicase family - - - 4.291e-199 631.0
CMS1_k127_539780_1 FAD linked - - - 3.817e-197 626.0
CMS1_k127_539780_2 SapC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 392.0
CMS1_k127_539780_3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
CMS1_k127_539780_4 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001172 278.0
CMS1_k127_539780_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000008484 235.0
CMS1_k127_539780_6 cheY-homologous receiver domain K13589 - - 0.0000000000000000000000000000000000000000000000000000001705 196.0
CMS1_k127_539780_7 - - - - 0.000000000000000000000000000000005468 133.0
CMS1_k127_539780_8 - - - - 0.0000000000000000000000000008635 120.0
CMS1_k127_539780_9 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000001493 94.0
CMS1_k127_5404485_0 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K00639,K00652 - 2.3.1.29,2.3.1.47 1.708e-231 719.0
CMS1_k127_5404485_1 YjgP YjgQ family K07091 - - 6.323e-199 625.0
CMS1_k127_5404485_2 YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 477.0
CMS1_k127_5404485_3 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 431.0
CMS1_k127_5404485_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
CMS1_k127_5404485_5 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 367.0
CMS1_k127_5404485_6 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 331.0
CMS1_k127_5404485_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000269 198.0
CMS1_k127_5404485_8 mRNA catabolic process - - - 0.00000000000000000000000000000000000000003358 163.0
CMS1_k127_5404485_9 acyl carrier protein - - - 0.0000000000000000000000000000002869 127.0
CMS1_k127_5419570_0 COG0457 FOG TPR repeat - - - 4.55e-259 809.0
CMS1_k127_5419570_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 567.0
CMS1_k127_5419570_10 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 315.0
CMS1_k127_5419570_11 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006108 253.0
CMS1_k127_5419570_12 Protein of unknown function (DUF1176) - - - 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
CMS1_k127_5419570_2 epoxide hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 479.0
CMS1_k127_5419570_3 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 429.0
CMS1_k127_5419570_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 427.0
CMS1_k127_5419570_5 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 419.0
CMS1_k127_5419570_6 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 382.0
CMS1_k127_5419570_7 Binding-protein-dependent transport system inner membrane component K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 388.0
CMS1_k127_5419570_8 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 368.0
CMS1_k127_5419570_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 351.0
CMS1_k127_5438766_0 Flavin-binding monooxygenase-like - - - 4.06e-211 676.0
CMS1_k127_5438766_1 Flavin-binding monooxygenase-like - - - 4.636e-200 634.0
CMS1_k127_5438766_10 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 327.0
CMS1_k127_5438766_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 293.0
CMS1_k127_5438766_12 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000005998 233.0
CMS1_k127_5438766_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000000001653 231.0
CMS1_k127_5438766_14 PilZ domain - - - 0.000000000000000000000001566 106.0
CMS1_k127_5438766_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 593.0
CMS1_k127_5438766_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 572.0
CMS1_k127_5438766_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 517.0
CMS1_k127_5438766_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 413.0
CMS1_k127_5438766_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
CMS1_k127_5438766_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 394.0
CMS1_k127_5438766_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 391.0
CMS1_k127_5438766_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 369.0
CMS1_k127_5443890_0 helicase K17675 - 3.6.4.13 5.673e-297 937.0
CMS1_k127_5443890_1 CarD family transcriptional regulator K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 305.0
CMS1_k127_5443890_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000000004339 223.0
CMS1_k127_5443890_3 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000001185 140.0
CMS1_k127_5443890_4 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000000002844 110.0
CMS1_k127_5443890_5 membrane - - - 0.000000000001224 72.0
CMS1_k127_5455133_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 7.881e-223 696.0
CMS1_k127_5455133_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 577.0
CMS1_k127_5455133_2 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
CMS1_k127_5455133_3 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
CMS1_k127_5455133_4 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
CMS1_k127_5455133_5 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000000000000000000000000281 190.0
CMS1_k127_5455133_6 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001479 180.0
CMS1_k127_5455133_7 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000009969 179.0
CMS1_k127_5474705_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1078.0
CMS1_k127_5474705_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1066.0
CMS1_k127_5474705_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000643 285.0
CMS1_k127_5474705_11 Domain of unknown function (DUF4115) - - - 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
CMS1_k127_5474705_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000004368 186.0
CMS1_k127_5474705_13 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000000000001118 125.0
CMS1_k127_5474705_14 Protein of unknown function (DUF465) - - - 0.0000000000000000002902 88.0
CMS1_k127_5474705_15 - - - - 0.00000000000002891 75.0
CMS1_k127_5474705_16 Small protein - - - 0.0000004239 52.0
CMS1_k127_5474705_17 - - - - 0.000002515 53.0
CMS1_k127_5474705_2 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.102e-220 689.0
CMS1_k127_5474705_3 Methionine synthase I (cobalamin-dependent), methyltransferase domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 548.0
CMS1_k127_5474705_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 504.0
CMS1_k127_5474705_5 beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
CMS1_k127_5474705_6 Phospholipase D Active site motif K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 391.0
CMS1_k127_5474705_7 ArsR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 345.0
CMS1_k127_5474705_8 NADH flavin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 333.0
CMS1_k127_5474705_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 284.0
CMS1_k127_5485175_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 1.883e-282 885.0
CMS1_k127_5485175_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 7.626e-238 747.0
CMS1_k127_5485175_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 306.0
CMS1_k127_5485175_11 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000789 290.0
CMS1_k127_5485175_12 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000001217 234.0
CMS1_k127_5485175_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000003719 196.0
CMS1_k127_5485175_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000000005887 160.0
CMS1_k127_5485175_15 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000001766 166.0
CMS1_k127_5485175_16 - - - - 0.000000000000000000000000000000000003506 149.0
CMS1_k127_5485175_17 SnoaL-like domain - - - 0.000000000000000000000000000214 120.0
CMS1_k127_5485175_18 - - - - 0.000000000000000006831 88.0
CMS1_k127_5485175_19 Histone deacetylase domain - - - 0.0001278 45.0
CMS1_k127_5485175_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 525.0
CMS1_k127_5485175_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 505.0
CMS1_k127_5485175_4 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 452.0
CMS1_k127_5485175_5 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 452.0
CMS1_k127_5485175_6 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 426.0
CMS1_k127_5485175_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
CMS1_k127_5485175_8 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 396.0
CMS1_k127_5485175_9 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 346.0
CMS1_k127_5507858_0 dehydratase K07749 - 2.8.3.16 1.623e-218 682.0
CMS1_k127_5507858_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 581.0
CMS1_k127_5507858_2 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 456.0
CMS1_k127_5507858_3 Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 438.0
CMS1_k127_5507858_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
CMS1_k127_5507858_5 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009137 264.0
CMS1_k127_5507858_6 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
CMS1_k127_5507858_7 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000004548 211.0
CMS1_k127_5512907_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1189.0
CMS1_k127_5512907_1 acyl-CoA dehydrogenase K20035 - - 3.136e-240 756.0
CMS1_k127_5512907_10 - - - - 0.0000002326 55.0
CMS1_k127_5512907_2 sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 589.0
CMS1_k127_5512907_3 ATPase (AAA superfamily) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 345.0
CMS1_k127_5512907_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 341.0
CMS1_k127_5512907_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
CMS1_k127_5512907_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 289.0
CMS1_k127_5512907_7 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000003677 121.0
CMS1_k127_5512907_8 - - - - 0.0000000000000000000009582 95.0
CMS1_k127_5512907_9 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000466 65.0
CMS1_k127_5533825_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1525.0
CMS1_k127_5533825_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 6.596e-310 965.0
CMS1_k127_5533825_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000002029 132.0
CMS1_k127_5533825_11 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000001943 79.0
CMS1_k127_5533825_12 - - - - 0.00001587 49.0
CMS1_k127_5533825_2 Protein involved in two-component response regulator activity and two-component signal transduction system (phosphorelay) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 393.0
CMS1_k127_5533825_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 355.0
CMS1_k127_5533825_4 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
CMS1_k127_5533825_5 Acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 291.0
CMS1_k127_5533825_6 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
CMS1_k127_5533825_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
CMS1_k127_5533825_8 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
CMS1_k127_5533825_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000001737 187.0
CMS1_k127_5536342_0 TonB dependent receptor - - - 0.0 1086.0
CMS1_k127_5536342_1 amidohydrolase K12941 - - 3.309e-236 737.0
CMS1_k127_5536342_10 attachment protein - - - 0.000000000000000000000000000000000000000000000000002119 184.0
CMS1_k127_5536342_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000002547 184.0
CMS1_k127_5536342_12 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000002759 178.0
CMS1_k127_5536342_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000002617 140.0
CMS1_k127_5536342_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. K21021 - 2.7.7.65 0.00000000000000000000000000001009 134.0
CMS1_k127_5536342_15 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000001133 115.0
CMS1_k127_5536342_16 Phasin protein - - - 0.000000000000000000000001222 114.0
CMS1_k127_5536342_17 - - - - 0.00000000000006845 74.0
CMS1_k127_5536342_18 PspC domain K03973 - - 0.0000000000001174 74.0
CMS1_k127_5536342_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
CMS1_k127_5536342_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 398.0
CMS1_k127_5536342_4 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 357.0
CMS1_k127_5536342_5 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 323.0
CMS1_k127_5536342_6 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
CMS1_k127_5536342_7 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009951 246.0
CMS1_k127_5536342_8 CHAP domain - - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
CMS1_k127_5536342_9 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000003038 205.0
CMS1_k127_5549451_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.228e-299 929.0
CMS1_k127_5549451_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 578.0
CMS1_k127_5549451_10 - - - - 0.000000000000009225 78.0
CMS1_k127_5549451_11 - - - - 0.0000008507 51.0
CMS1_k127_5549451_2 Sulfotransferase domain K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 474.0
CMS1_k127_5549451_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 351.0
CMS1_k127_5549451_4 - - - - 0.000000000000000000000000000000000000001579 150.0
CMS1_k127_5549451_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0000000000000000000000000000000008497 134.0
CMS1_k127_5549451_6 - - - - 0.000000000000000000000000000000819 123.0
CMS1_k127_5549451_7 protein conserved in bacteria - - - 0.00000000000000000009855 91.0
CMS1_k127_5549451_8 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase K06147 - - 0.00000000000000002227 83.0
CMS1_k127_5549451_9 - - - - 0.000000000000001011 79.0
CMS1_k127_5551713_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 1.343e-267 844.0
CMS1_k127_5551713_1 acyl-CoA dehydrogenase - - - 1.462e-228 711.0
CMS1_k127_5551713_10 - - - - 0.0000000000000000000000000000000000000000000000000003862 193.0
CMS1_k127_5551713_11 Cytochrome c K08738 - - 0.00000000000000000000000000001245 125.0
CMS1_k127_5551713_12 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000008462 124.0
CMS1_k127_5551713_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 544.0
CMS1_k127_5551713_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 480.0
CMS1_k127_5551713_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 439.0
CMS1_k127_5551713_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 398.0
CMS1_k127_5551713_6 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 344.0
CMS1_k127_5551713_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 328.0
CMS1_k127_5551713_8 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000008279 246.0
CMS1_k127_5551713_9 - - - - 0.000000000000000000000000000000000000000000000000000000002179 209.0
CMS1_k127_5561997_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1084.0
CMS1_k127_5561997_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.49e-208 658.0
CMS1_k127_5561997_10 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000000000000003736 126.0
CMS1_k127_5561997_11 - - - - 0.00000000000001016 77.0
CMS1_k127_5561997_12 Phosphate ABC transporter substrate-binding protein K02040 - - 0.000000001235 61.0
CMS1_k127_5561997_2 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 406.0
CMS1_k127_5561997_3 HPr kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 389.0
CMS1_k127_5561997_4 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 396.0
CMS1_k127_5561997_5 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007188 268.0
CMS1_k127_5561997_6 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000003117 198.0
CMS1_k127_5561997_7 - - - - 0.000000000000000000000000000000000000000000000000000104 189.0
CMS1_k127_5561997_8 OsmC-like protein K06889,K07397 - - 0.00000000000000000000000000000000000000000003144 169.0
CMS1_k127_5561997_9 - - - - 0.000000000000000000000000000000000000000007065 164.0
CMS1_k127_556535_0 protein conserved in bacteria - - - 1.462e-276 861.0
CMS1_k127_556535_1 Oxidoreductase - - - 5.104e-246 769.0
CMS1_k127_556535_2 Protein of unknown function (DUF3604) - - - 1.756e-243 768.0
CMS1_k127_556535_3 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 488.0
CMS1_k127_556535_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009783 272.0
CMS1_k127_556535_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001987 200.0
CMS1_k127_556535_6 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0004308 46.0
CMS1_k127_5576848_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 454.0
CMS1_k127_5576848_1 OmpW family K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 313.0
CMS1_k127_5576848_2 - - - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
CMS1_k127_5576848_3 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000005302 132.0
CMS1_k127_5576848_4 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000001334 100.0
CMS1_k127_5585408_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.005e-268 833.0
CMS1_k127_5585408_1 Threonine synthase K01733 - 4.2.3.1 1.167e-231 724.0
CMS1_k127_5585408_10 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000006091 193.0
CMS1_k127_5585408_11 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000003633 184.0
CMS1_k127_5585408_12 EVE domain - - - 0.00000000000000000000000000000000000000000000000004915 184.0
CMS1_k127_5585408_13 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000000004928 166.0
CMS1_k127_5585408_14 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000002224 145.0
CMS1_k127_5585408_15 Fasciclin - - - 0.00000000000000000000000005149 114.0
CMS1_k127_5585408_16 - - - - 0.0009364 50.0
CMS1_k127_5585408_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.297e-194 618.0
CMS1_k127_5585408_3 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 493.0
CMS1_k127_5585408_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 453.0
CMS1_k127_5585408_5 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 430.0
CMS1_k127_5585408_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 403.0
CMS1_k127_5585408_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008822 264.0
CMS1_k127_5585408_8 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 259.0
CMS1_k127_5585408_9 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002666 245.0
CMS1_k127_5602627_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 9.171e-208 660.0
CMS1_k127_5602627_1 related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
CMS1_k127_5602627_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 346.0
CMS1_k127_5602627_3 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
CMS1_k127_5602627_4 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 309.0
CMS1_k127_5602627_5 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000002218 171.0
CMS1_k127_5602627_6 - - - - 0.0000000000000000000000000000000000000000000002513 172.0
CMS1_k127_5602627_7 - - - - 0.00000000000000000000000000000000004601 146.0
CMS1_k127_5604556_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.707e-301 928.0
CMS1_k127_5604556_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.038e-215 675.0
CMS1_k127_5604556_2 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 557.0
CMS1_k127_5604556_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 312.0
CMS1_k127_5604556_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 294.0
CMS1_k127_5604556_5 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000000438 123.0
CMS1_k127_5608645_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1369.0
CMS1_k127_5608645_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.131e-252 792.0
CMS1_k127_5608645_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 3.275e-242 751.0
CMS1_k127_5608645_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 490.0
CMS1_k127_5608645_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 478.0
CMS1_k127_5608645_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 374.0
CMS1_k127_5608645_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 360.0
CMS1_k127_5608645_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 338.0
CMS1_k127_5608645_8 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
CMS1_k127_5608645_9 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000002681 105.0
CMS1_k127_5637966_0 DNA helicase K03657 - 3.6.4.12 0.0 1180.0
CMS1_k127_5637966_1 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000001624 109.0
CMS1_k127_5637966_3 - - - - 0.00000000002571 67.0
CMS1_k127_5642678_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1111.0
CMS1_k127_5642678_1 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 421.0
CMS1_k127_5642678_2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 354.0
CMS1_k127_5642678_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 318.0
CMS1_k127_5642678_4 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 310.0
CMS1_k127_5642678_5 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000000000000001656 173.0
CMS1_k127_5642678_6 - - - - 0.0000000000000000000000000000000000000005815 151.0
CMS1_k127_5642678_7 - - - - 0.0000000000000000000000000000000002241 134.0
CMS1_k127_5642678_8 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000005071 119.0
CMS1_k127_5642678_9 Protein of unknown function (DUF1289) K06938 - - 0.00000001017 61.0
CMS1_k127_5643312_0 protein conserved in bacteria - - - 0.0 1042.0
CMS1_k127_5643312_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 5.379e-256 807.0
CMS1_k127_5643312_2 COG2831 Hemolysin activation secretion protein - - - 5.814e-202 645.0
CMS1_k127_5643312_3 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 595.0
CMS1_k127_5643312_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 336.0
CMS1_k127_5643312_5 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000000000000000000000000000000002694 211.0
CMS1_k127_5643312_6 - - - - 0.000000000000000000000000000000000000000000000000004077 192.0
CMS1_k127_5730983_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.861e-268 831.0
CMS1_k127_5730983_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.728e-198 627.0
CMS1_k127_5730983_2 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 574.0
CMS1_k127_5730983_3 Lycopene cyclase protein K06443 - 5.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 415.0
CMS1_k127_5730983_4 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 369.0
CMS1_k127_5730983_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 353.0
CMS1_k127_5730983_6 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 320.0
CMS1_k127_5730983_7 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
CMS1_k127_5730983_8 - - - - 0.0000000000000000000000002831 110.0
CMS1_k127_5739677_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.122e-272 850.0
CMS1_k127_5739677_1 Heparinase - - - 1.304e-203 649.0
CMS1_k127_5739677_10 Belongs to the UPF0235 family K09131 - - 0.0000000000000008167 81.0
CMS1_k127_5739677_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 479.0
CMS1_k127_5739677_3 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 422.0
CMS1_k127_5739677_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 377.0
CMS1_k127_5739677_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 380.0
CMS1_k127_5739677_6 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 316.0
CMS1_k127_5739677_7 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000007269 222.0
CMS1_k127_5739677_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000001982 214.0
CMS1_k127_5739677_9 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000000000000003628 166.0
CMS1_k127_5750874_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1549.0
CMS1_k127_5750874_1 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 5.487e-258 807.0
CMS1_k127_5750874_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000007068 163.0
CMS1_k127_5750874_3 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000000000000109 138.0
CMS1_k127_5758207_0 Heat shock 70 kDa protein K04043 - - 2.386e-225 704.0
CMS1_k127_5758207_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 555.0
CMS1_k127_5758207_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 311.0
CMS1_k127_5758207_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
CMS1_k127_5758207_4 Protein of unknown function (DUF3376) - - - 0.000000000000000000000000000000000000000000000000000000008729 200.0
CMS1_k127_5760123_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.646e-308 951.0
CMS1_k127_5760123_1 phosphomannomutase K01840 - 5.4.2.8 8.775e-244 760.0
CMS1_k127_5760123_2 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
CMS1_k127_5760123_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 348.0
CMS1_k127_5760123_4 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 288.0
CMS1_k127_5760123_5 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000004862 201.0
CMS1_k127_5760123_6 DnaJ molecular chaperone homology domain - - - 0.00000000000002793 78.0
CMS1_k127_5793905_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 541.0
CMS1_k127_5793905_1 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 514.0
CMS1_k127_5793905_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 340.0
CMS1_k127_5793905_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001982 277.0
CMS1_k127_5798907_0 receptor K02014 - - 0.0 1234.0
CMS1_k127_5798907_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 552.0
CMS1_k127_5798907_2 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 543.0
CMS1_k127_5798907_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 374.0
CMS1_k127_5798907_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001319 265.0
CMS1_k127_5805966_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 413.0
CMS1_k127_5805966_1 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 347.0
CMS1_k127_5805966_2 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000000000000000000000000000000005531 203.0
CMS1_k127_5808818_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 474.0
CMS1_k127_5808818_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
CMS1_k127_5808818_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
CMS1_k127_5808818_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001483 256.0
CMS1_k127_5838036_0 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 490.0
CMS1_k127_5838036_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 258.0
CMS1_k127_5838036_2 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000001044 222.0
CMS1_k127_5838036_3 Acyl-CoA hydrolase K10806 - - 0.0000000000000000000000000000000000000000000000002303 180.0
CMS1_k127_5838036_4 CBS domain - - - 0.000000000000000000000000000000000000000000000001613 177.0
CMS1_k127_5838036_5 - - - - 0.0000000000000000000000000001099 118.0
CMS1_k127_5845455_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1029.0
CMS1_k127_5845455_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000009137 196.0
CMS1_k127_5863236_0 P-type ATPase K17686 - 3.6.3.54 0.0 1146.0
CMS1_k127_5863236_1 Multicopper oxidase - - - 6.54e-255 799.0
CMS1_k127_5863236_2 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 368.0
CMS1_k127_5863236_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
CMS1_k127_5863236_4 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000426 196.0
CMS1_k127_5863236_5 Copper resistance K07233 - - 0.0000000000000000000000000000000000000002905 154.0
CMS1_k127_5863236_6 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000000000000836 139.0
CMS1_k127_5863236_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000001637 68.0
CMS1_k127_5863236_8 Multicopper oxidase - - - 0.00000005765 59.0
CMS1_k127_5872895_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.723e-231 722.0
CMS1_k127_5872895_1 Major facilitator superfamily K03446 - - 4.387e-215 679.0
CMS1_k127_5872895_10 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 323.0
CMS1_k127_5872895_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 319.0
CMS1_k127_5872895_12 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 282.0
CMS1_k127_5872895_13 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 275.0
CMS1_k127_5872895_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000009154 226.0
CMS1_k127_5872895_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000108 214.0
CMS1_k127_5872895_16 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000000000000000011 202.0
CMS1_k127_5872895_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000002165 198.0
CMS1_k127_5872895_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000003764 168.0
CMS1_k127_5872895_19 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000001739 106.0
CMS1_k127_5872895_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 1.58e-202 645.0
CMS1_k127_5872895_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 6.618e-195 612.0
CMS1_k127_5872895_4 2-methylthioadenine K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 556.0
CMS1_k127_5872895_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 475.0
CMS1_k127_5872895_6 Secretion protein, HlyD K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 419.0
CMS1_k127_5872895_7 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 389.0
CMS1_k127_5872895_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 377.0
CMS1_k127_5872895_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 364.0
CMS1_k127_5882428_0 Serine dehydratase K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 578.0
CMS1_k127_5882428_1 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 431.0
CMS1_k127_5882428_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 399.0
CMS1_k127_5882428_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 387.0
CMS1_k127_5882428_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002056 267.0
CMS1_k127_5882428_5 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000000000007943 126.0
CMS1_k127_5882428_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000009587 64.0
CMS1_k127_5890605_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1300.0
CMS1_k127_5890605_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 557.0
CMS1_k127_5890605_2 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000000000005083 165.0
CMS1_k127_5890605_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000001318 152.0
CMS1_k127_5890605_4 COG3279 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000003472 154.0
CMS1_k127_5890605_5 - - - - 0.00000000000000000000000000000001455 135.0
CMS1_k127_5890605_6 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000007393 86.0
CMS1_k127_5912759_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.718e-299 927.0
CMS1_k127_5912759_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.216e-280 870.0
CMS1_k127_5912759_10 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 352.0
CMS1_k127_5912759_11 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 322.0
CMS1_k127_5912759_12 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 301.0
CMS1_k127_5912759_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000171 267.0
CMS1_k127_5912759_14 acetolactate synthase K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 259.0
CMS1_k127_5912759_15 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000000005561 200.0
CMS1_k127_5912759_16 - - - - 0.000000000000000000000000000000002272 141.0
CMS1_k127_5912759_17 Sensors of blue-light using FAD - - - 0.000000000000001929 82.0
CMS1_k127_5912759_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.355e-202 632.0
CMS1_k127_5912759_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 536.0
CMS1_k127_5912759_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 526.0
CMS1_k127_5912759_5 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 519.0
CMS1_k127_5912759_6 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 441.0
CMS1_k127_5912759_7 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 414.0
CMS1_k127_5912759_8 Protein of unknown function (DUF3089) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 357.0
CMS1_k127_5912759_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 357.0
CMS1_k127_5995629_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 4.027e-321 990.0
CMS1_k127_5995629_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 305.0
CMS1_k127_5995629_2 Alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000006701 214.0
CMS1_k127_6019395_0 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 530.0
CMS1_k127_6019395_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 466.0
CMS1_k127_6019395_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
CMS1_k127_6019395_3 alcohol dehydrogenase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 405.0
CMS1_k127_6019395_4 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000000000000005226 178.0
CMS1_k127_6019395_5 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000004768 133.0
CMS1_k127_6019395_6 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000001781 79.0
CMS1_k127_6021777_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 608.0
CMS1_k127_6021777_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 571.0
CMS1_k127_6021777_2 - - - - 0.00000000000000000000000000000000000000000000000001428 188.0
CMS1_k127_6029509_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 2.372e-278 865.0
CMS1_k127_6029509_1 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 398.0
CMS1_k127_6029509_2 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 372.0
CMS1_k127_6029509_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 360.0
CMS1_k127_6048063_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 591.0
CMS1_k127_6048063_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 531.0
CMS1_k127_6048063_10 - - - - 0.000000000000000001103 95.0
CMS1_k127_6048063_11 Pilus assembly protein PilZ - - - 0.000000000000001192 80.0
CMS1_k127_6048063_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 398.0
CMS1_k127_6048063_3 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 304.0
CMS1_k127_6048063_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 284.0
CMS1_k127_6048063_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000004375 210.0
CMS1_k127_6048063_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000004883 209.0
CMS1_k127_6048063_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000267 176.0
CMS1_k127_6048063_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000006011 174.0
CMS1_k127_6048063_9 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000000005378 160.0
CMS1_k127_6088226_0 receptor - - - 0.0 1333.0
CMS1_k127_6088226_1 Major Facilitator - - - 1.033e-288 894.0
CMS1_k127_6088226_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 308.0
CMS1_k127_6088226_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
CMS1_k127_6088226_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 250.0
CMS1_k127_6088226_13 Hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005634 252.0
CMS1_k127_6088226_14 Sulfotransferase domain K01015 - 2.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000001386 250.0
CMS1_k127_6088226_15 Retinal pigment epithelial membrane protein K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000001903 238.0
CMS1_k127_6088226_16 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000004925 234.0
CMS1_k127_6088226_17 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000006949 168.0
CMS1_k127_6088226_18 - - - - 0.000000000000000000000000000000000000000000008673 172.0
CMS1_k127_6088226_19 - - - - 0.000000000000000000000000000000000000000001209 159.0
CMS1_k127_6088226_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 2.774e-284 882.0
CMS1_k127_6088226_20 Belongs to the UPF0335 family - - - 0.000000000000000000000000000000001391 131.0
CMS1_k127_6088226_21 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000005569 121.0
CMS1_k127_6088226_22 CAAX protease self-immunity - - - 0.000000000000000008919 98.0
CMS1_k127_6088226_23 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001029 79.0
CMS1_k127_6088226_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K20034 - 6.2.1.44 7.324e-275 857.0
CMS1_k127_6088226_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.27e-209 659.0
CMS1_k127_6088226_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 577.0
CMS1_k127_6088226_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 560.0
CMS1_k127_6088226_7 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 556.0
CMS1_k127_6088226_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 423.0
CMS1_k127_6088226_9 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 390.0
CMS1_k127_6094429_0 ATP-dependent DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 9.184e-254 796.0
CMS1_k127_6094429_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 427.0
CMS1_k127_6094429_2 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 421.0
CMS1_k127_6094429_3 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 410.0
CMS1_k127_6094429_4 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 364.0
CMS1_k127_6094429_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007654 254.0
CMS1_k127_6094429_6 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002536 246.0
CMS1_k127_6094429_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000006904 224.0
CMS1_k127_6094429_8 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000007113 190.0
CMS1_k127_6094429_9 ArsR family transcriptional regulator K03892 - - 0.000000000000000000000000000000000008897 140.0
CMS1_k127_6144128_0 Domain of unknown function (DUF5117) - - - 0.0 1237.0
CMS1_k127_6144128_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 596.0
CMS1_k127_6144128_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 578.0
CMS1_k127_6144128_3 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 357.0
CMS1_k127_6144128_4 - - - - 0.0000000000000000000000000000000000000000000000001412 188.0
CMS1_k127_6144128_5 - - - - 0.0000000000000000003577 91.0
CMS1_k127_6144128_7 Protein of unknown function (DUF3500) - - - 0.0000000004352 61.0
CMS1_k127_6268455_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1256.0
CMS1_k127_6268455_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.95e-214 682.0
CMS1_k127_6268455_10 - - - - 0.00000000001811 66.0
CMS1_k127_6268455_2 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 467.0
CMS1_k127_6268455_3 Alpha Beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 412.0
CMS1_k127_6268455_4 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 398.0
CMS1_k127_6268455_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000105 164.0
CMS1_k127_6268455_6 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000001212 159.0
CMS1_k127_6268455_7 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000002826 157.0
CMS1_k127_6268455_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000002253 143.0
CMS1_k127_6268455_9 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000003461 139.0
CMS1_k127_636438_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 321.0
CMS1_k127_636438_1 - - - - 0.00000000000000000000000000000000000000000000001032 176.0
CMS1_k127_636438_2 META domain - - - 0.000000000000000000000000000001205 128.0
CMS1_k127_636438_3 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000001125 91.0
CMS1_k127_653709_0 ATPase with chaperone activity K07391 - - 3.099e-258 804.0
CMS1_k127_653709_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 578.0
CMS1_k127_653709_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002158 79.0
CMS1_k127_653709_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 551.0
CMS1_k127_653709_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 361.0
CMS1_k127_653709_4 periplasmic protein - - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
CMS1_k127_653709_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000318 134.0
CMS1_k127_653709_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001039 123.0
CMS1_k127_653709_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000003082 118.0
CMS1_k127_653709_8 - - - - 0.00000000000000000011 92.0
CMS1_k127_653709_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000004187 88.0
CMS1_k127_679630_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.651e-285 886.0
CMS1_k127_679630_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 5.22e-266 830.0
CMS1_k127_679630_10 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 431.0
CMS1_k127_679630_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 393.0
CMS1_k127_679630_12 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 366.0
CMS1_k127_679630_13 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 343.0
CMS1_k127_679630_14 Two component transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
CMS1_k127_679630_15 Cell Wall - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 316.0
CMS1_k127_679630_16 uracil-dna glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003234 274.0
CMS1_k127_679630_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002035 274.0
CMS1_k127_679630_18 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006005 273.0
CMS1_k127_679630_19 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002493 246.0
CMS1_k127_679630_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 6.181e-250 776.0
CMS1_k127_679630_20 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001666 235.0
CMS1_k127_679630_21 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
CMS1_k127_679630_22 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
CMS1_k127_679630_23 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
CMS1_k127_679630_24 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000004063 230.0
CMS1_k127_679630_25 - - - - 0.0000000000000000000000000000000000000000000000000000000004244 210.0
CMS1_k127_679630_26 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000008533 202.0
CMS1_k127_679630_27 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
CMS1_k127_679630_28 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000000000004041 190.0
CMS1_k127_679630_29 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000003379 196.0
CMS1_k127_679630_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.052e-200 632.0
CMS1_k127_679630_30 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000006766 186.0
CMS1_k127_679630_31 Hemerythrin - - - 0.000000000000000000000000000000000000000000000002004 177.0
CMS1_k127_679630_32 - - - - 0.00000000000000000000000000000009213 138.0
CMS1_k127_679630_33 PilZ domain - - - 0.0000000000000000000000000000004435 127.0
CMS1_k127_679630_34 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000001944 125.0
CMS1_k127_679630_35 - - - - 0.000000000000000003218 87.0
CMS1_k127_679630_37 - - - - 0.0000006864 51.0
CMS1_k127_679630_39 COG1226 Kef-type K transport systems K10716 - - 0.0003415 46.0
CMS1_k127_679630_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 571.0
CMS1_k127_679630_5 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 544.0
CMS1_k127_679630_6 carnitine dehydratase K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 531.0
CMS1_k127_679630_7 in Escherichia coli this protein forms a dimer and binds manganese K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 499.0
CMS1_k127_679630_8 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 456.0
CMS1_k127_679630_9 COG0534 Na -driven multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 448.0
CMS1_k127_693695_0 Outer membrane protein beta-barrel family - - - 2.274e-309 965.0
CMS1_k127_693695_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K16051 - 1.3.99.5 4.567e-205 654.0
CMS1_k127_694650_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.327e-269 833.0
CMS1_k127_694650_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 346.0
CMS1_k127_694650_2 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000001119 178.0
CMS1_k127_694650_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000002409 147.0
CMS1_k127_694650_4 Ribosomal protein S6 modification protein - - - 0.000000003166 59.0
CMS1_k127_69865_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.58e-314 973.0
CMS1_k127_69865_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 531.0
CMS1_k127_69865_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 375.0
CMS1_k127_69865_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
CMS1_k127_69865_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000008819 153.0
CMS1_k127_69865_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000001906 110.0
CMS1_k127_71602_0 Alkaline phosphatase K01113 - 3.1.3.1 5.891e-218 688.0
CMS1_k127_71602_1 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 266.0
CMS1_k127_71602_2 Aminotransferase K14261 - - 0.0000000000000000000000000000000000000000000000000000000001317 204.0
CMS1_k127_739622_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.174e-270 835.0
CMS1_k127_739622_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 430.0
CMS1_k127_746870_0 Peptidase, M28 - - - 1.021e-262 821.0
CMS1_k127_746870_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.321e-260 809.0
CMS1_k127_746870_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000002787 154.0
CMS1_k127_746870_11 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.00000000000000000000000000000000005507 139.0
CMS1_k127_746870_2 Prolyl oligopeptidase - - - 2.209e-204 655.0
CMS1_k127_746870_3 N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 488.0
CMS1_k127_746870_4 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 481.0
CMS1_k127_746870_5 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 392.0
CMS1_k127_746870_6 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 361.0
CMS1_k127_746870_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 322.0
CMS1_k127_746870_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 293.0
CMS1_k127_746870_9 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
CMS1_k127_748767_0 Histidine kinase K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 549.0
CMS1_k127_748767_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
CMS1_k127_748767_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 379.0
CMS1_k127_748767_3 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000006681 196.0
CMS1_k127_748767_4 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000001227 174.0
CMS1_k127_748767_5 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.0000000000000000000000000005773 120.0
CMS1_k127_748767_6 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000004109 53.0
CMS1_k127_807961_0 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 466.0
CMS1_k127_807961_1 Oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 418.0
CMS1_k127_807961_2 Pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 366.0
CMS1_k127_807961_3 Lysophospholipase K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 342.0
CMS1_k127_807961_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 299.0
CMS1_k127_807961_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000004636 236.0
CMS1_k127_807961_6 peptidase K02278 - 3.4.23.43 0.00000000000000000000000000000000000000000004372 165.0
CMS1_k127_807961_7 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000001006 93.0
CMS1_k127_856061_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 5.45e-299 921.0
CMS1_k127_856061_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.409e-217 682.0
CMS1_k127_856061_2 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 7.109e-198 631.0
CMS1_k127_856061_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 428.0
CMS1_k127_856061_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 379.0
CMS1_k127_856061_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 366.0
CMS1_k127_856061_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000004642 252.0
CMS1_k127_856061_7 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000000000000000000000000000000000000000006103 235.0
CMS1_k127_856061_8 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
CMS1_k127_856061_9 protein conserved in bacteria K09781 - - 0.000000000000000000000001768 103.0
CMS1_k127_86038_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 3.997e-286 894.0
CMS1_k127_86038_1 Metal-dependent hydrolase - - - 9.412e-239 749.0
CMS1_k127_86038_10 Belongs to the UPF0262 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008886 271.0
CMS1_k127_86038_11 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001353 274.0
CMS1_k127_86038_12 ABC transporter K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000002196 240.0
CMS1_k127_86038_13 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000000006412 229.0
CMS1_k127_86038_14 chain release factor K15034 - - 0.0000000000000000000000000000000000000000003373 164.0
CMS1_k127_86038_15 Nickel/cobalt transporter regulator - - - 0.000000000000000000000000000000000002157 155.0
CMS1_k127_86038_2 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 555.0
CMS1_k127_86038_3 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 531.0
CMS1_k127_86038_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 458.0
CMS1_k127_86038_5 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 462.0
CMS1_k127_86038_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 414.0
CMS1_k127_86038_7 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 404.0
CMS1_k127_86038_8 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
CMS1_k127_86038_9 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 337.0
CMS1_k127_885012_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1018.0
CMS1_k127_885012_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
CMS1_k127_885012_2 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000006554 121.0
CMS1_k127_895565_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 472.0
CMS1_k127_895565_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 327.0
CMS1_k127_895565_2 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 298.0
CMS1_k127_895565_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001901 280.0
CMS1_k127_895565_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005759 275.0
CMS1_k127_895565_5 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000002447 198.0
CMS1_k127_903570_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 576.0
CMS1_k127_903570_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 326.0
CMS1_k127_903570_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000008401 203.0
CMS1_k127_903570_3 response regulator K02282,K07782,K19135 - - 0.00000000000000000000000000000626 126.0
CMS1_k127_903570_4 - - - - 0.00000000000001589 76.0
CMS1_k127_903570_5 DSBA-like thioredoxin domain - - - 0.000000004148 57.0
CMS1_k127_916387_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 546.0
CMS1_k127_916387_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
CMS1_k127_916387_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000002789 196.0
CMS1_k127_916387_3 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000002444 152.0
CMS1_k127_916387_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000229 91.0
CMS1_k127_917688_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 575.0
CMS1_k127_917688_1 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 470.0
CMS1_k127_917688_10 - - - - 0.00000000000000000000000000003598 121.0
CMS1_k127_917688_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 332.0
CMS1_k127_917688_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000933 284.0
CMS1_k127_917688_4 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009707 271.0
CMS1_k127_917688_5 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 237.0
CMS1_k127_917688_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002297 203.0
CMS1_k127_917688_7 small membrane protein - - - 0.000000000000000000000000000000000000000000000000001173 184.0
CMS1_k127_917688_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000001155 156.0
CMS1_k127_917688_9 transcriptional - - - 0.0000000000000000000000000000004034 126.0
CMS1_k127_923129_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 580.0
CMS1_k127_923129_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000003545 147.0
CMS1_k127_923129_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000003047 116.0
CMS1_k127_923129_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000004252 62.0
CMS1_k127_929442_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1368.0
CMS1_k127_929442_1 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 2.829e-286 888.0
CMS1_k127_929442_2 oxidase, subunit K00425 - 1.10.3.14 1.621e-256 796.0
CMS1_k127_929442_3 oxidase subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 569.0
CMS1_k127_929442_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000005628 216.0
CMS1_k127_929442_5 DoxX - - - 0.000000000000000000000000000000000000000000000000003035 191.0
CMS1_k127_929442_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000001878 155.0
CMS1_k127_929442_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000003344 150.0
CMS1_k127_929442_8 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000001791 132.0
CMS1_k127_929442_9 MAPEG family - - - 0.00000000000000000000005676 112.0
CMS1_k127_936678_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1304.0
CMS1_k127_936678_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 609.0
CMS1_k127_936678_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 505.0
CMS1_k127_936678_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 359.0
CMS1_k127_936678_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 364.0
CMS1_k127_936678_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000006489 191.0
CMS1_k127_936678_6 GDYXXLXY protein - - - 0.000000000000000000000000000000002125 140.0
CMS1_k127_936678_7 - - - - 0.00000000000000000000000000004732 121.0
CMS1_k127_936678_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000006682 109.0
CMS1_k127_936678_9 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000175 94.0
CMS1_k127_941367_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.188e-261 811.0
CMS1_k127_941367_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 510.0
CMS1_k127_941367_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 314.0
CMS1_k127_941367_3 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
CMS1_k127_941367_4 hydroxylase K15746 - 1.14.15.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 306.0
CMS1_k127_941367_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
CMS1_k127_941367_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000009574 184.0
CMS1_k127_941367_7 Domain of unknown function (DUF1476) - - - 0.00000000000000000000000000000000000000000025 161.0
CMS1_k127_941367_8 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000001942 115.0
CMS1_k127_941367_9 - - - - 0.0000000000002126 80.0
CMS1_k127_965999_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.671e-279 871.0
CMS1_k127_965999_1 Chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 407.0
CMS1_k127_965999_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
CMS1_k127_965999_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000365 219.0
CMS1_k127_973165_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 434.0
CMS1_k127_973165_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 418.0
CMS1_k127_973165_2 Ion transport protein K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
CMS1_k127_973165_3 riboflavin biosynthesis protein RIBA K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 297.0
CMS1_k127_973165_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000476 279.0
CMS1_k127_973165_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 255.0
CMS1_k127_973165_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000001334 220.0
CMS1_k127_973165_7 SOS response K14160 - - 0.000000000000000000000000000000000000000000006246 176.0
CMS1_k127_973165_8 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000002018 158.0
CMS1_k127_973165_9 - - - - 0.000000000000000000008359 99.0
CMS1_k127_982479_0 Nitrogenase component 1 type Oxidoreductase K11334 - 1.3.7.14,1.3.7.15 1.815e-272 844.0
CMS1_k127_982479_1 Proto-chlorophyllide reductase 57 kD subunit K11335 - 1.3.7.14,1.3.7.15 1.583e-262 822.0
CMS1_k127_982479_10 Dehydrogenase K11337 - 1.1.1.396 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 433.0
CMS1_k127_982479_11 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 357.0
CMS1_k127_982479_12 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
CMS1_k127_982479_13 hydroxyneurosporene synthase K09844 - 4.2.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 336.0
CMS1_k127_982479_14 Alpha/beta hydrolase family K06049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 329.0
CMS1_k127_982479_15 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 307.0
CMS1_k127_982479_16 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 286.0
CMS1_k127_982479_17 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000001308 213.0
CMS1_k127_982479_18 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
CMS1_k127_982479_19 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000006863 197.0
CMS1_k127_982479_2 Acetyl-CoA hydrolase/transferase C-terminal domain K18288 - - 1.284e-203 641.0
CMS1_k127_982479_20 Antenna complex alpha/beta subunit K08927 - - 0.000000000000000000000000000005019 120.0
CMS1_k127_982479_21 Antenna complex alpha/beta subunit K08926 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000001561 95.0
CMS1_k127_982479_22 - - - - 0.00000000000000001283 92.0
CMS1_k127_982479_23 - - - - 0.0000000000000004065 83.0
CMS1_k127_982479_3 Belongs to the NifH BchL ChlL family K11333 - 1.3.7.14,1.3.7.15 2.236e-198 620.0
CMS1_k127_982479_4 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 8.15e-198 629.0
CMS1_k127_982479_5 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 538.0
CMS1_k127_982479_6 Belongs to the reaction center PufL M PsbA D family K08928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 507.0
CMS1_k127_982479_7 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 492.0
CMS1_k127_982479_8 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 470.0
CMS1_k127_982479_9 von Willebrand factor type A domain K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 478.0
CMS1_k127_989053_0 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 6.831e-229 721.0
CMS1_k127_989053_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.987e-222 698.0
CMS1_k127_989053_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 571.0
CMS1_k127_989053_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 559.0
CMS1_k127_989053_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 543.0
CMS1_k127_989053_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 545.0
CMS1_k127_989053_6 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 531.0
CMS1_k127_989053_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 400.0
CMS1_k127_989053_8 - - - - 0.000000000000000000000000000000000003511 145.0
CMS1_k127_992119_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.0 1061.0
CMS1_k127_992119_1 cell adhesion involved in biofilm formation - - - 4.046e-198 628.0
CMS1_k127_992119_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 483.0
CMS1_k127_992119_3 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 331.0
CMS1_k127_992119_4 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 303.0
CMS1_k127_992119_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003189 133.0
CMS1_k127_992119_7 Histidine kinase - - - 0.000000000000000000000000000000296 125.0
CMS1_k127_992119_8 - - - - 0.0000000000000000006149 91.0