Overview

ID MAG00461
Name CMS2_bin.75
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Thiohalomonadales
Family Thiohalomonadaceae
Genus JBFEYJ01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 2.2
GC content (%) 57.0
N50 (bp) 30,447
Genome size (bp) 3,126,796

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2772

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_102730_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 594.0
CMS2_k127_102730_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 563.0
CMS2_k127_1041095_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1498.0
CMS2_k127_1041095_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 520.0
CMS2_k127_1041095_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000003759 164.0
CMS2_k127_1041095_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000001507 156.0
CMS2_k127_1041095_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 502.0
CMS2_k127_1041095_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 496.0
CMS2_k127_1041095_4 major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 478.0
CMS2_k127_1041095_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 443.0
CMS2_k127_1041095_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 322.0
CMS2_k127_1041095_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001875 261.0
CMS2_k127_1041095_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000009019 216.0
CMS2_k127_1041095_9 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001386 211.0
CMS2_k127_105216_0 DNA polymerase III alpha subunit K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1491.0
CMS2_k127_105216_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.426e-282 878.0
CMS2_k127_105216_10 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 420.0
CMS2_k127_105216_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 402.0
CMS2_k127_105216_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 376.0
CMS2_k127_105216_13 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 332.0
CMS2_k127_105216_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 322.0
CMS2_k127_105216_15 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 293.0
CMS2_k127_105216_16 helix_turn_helix, Lux Regulon K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
CMS2_k127_105216_17 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 283.0
CMS2_k127_105216_18 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
CMS2_k127_105216_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 253.0
CMS2_k127_105216_2 aminotransferase class I and II K14261 - - 5.451e-228 710.0
CMS2_k127_105216_20 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000008299 252.0
CMS2_k127_105216_21 PFAM O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000535 236.0
CMS2_k127_105216_22 Peptidase family M23 K06194 - - 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
CMS2_k127_105216_23 Smr protein - - - 0.000000000000000000000000000000000000000000000000000000001835 205.0
CMS2_k127_105216_24 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000934 185.0
CMS2_k127_105216_25 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - 0.000000000000000000000000003337 112.0
CMS2_k127_105216_26 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000001364 102.0
CMS2_k127_105216_3 DHH family K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 5.158e-227 718.0
CMS2_k127_105216_4 Aminotransferase AlaT K14260 - 2.6.1.2,2.6.1.66 7.382e-226 704.0
CMS2_k127_105216_5 homoserine dehydrogenase K00003 - 1.1.1.3 1.322e-210 661.0
CMS2_k127_105216_6 threonine synthase K01733 - 4.2.3.1 7.947e-210 656.0
CMS2_k127_105216_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.429e-195 617.0
CMS2_k127_105216_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 505.0
CMS2_k127_105216_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 468.0
CMS2_k127_1073288_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 542.0
CMS2_k127_1073288_1 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 422.0
CMS2_k127_1073288_10 Paraquat-inducible protein A - - - 0.00000000000000000000000005641 113.0
CMS2_k127_1073288_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 413.0
CMS2_k127_1073288_3 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 406.0
CMS2_k127_1073288_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 336.0
CMS2_k127_1073288_5 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 319.0
CMS2_k127_1073288_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 298.0
CMS2_k127_1073288_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000003008 230.0
CMS2_k127_1073288_8 transcriptional regulators K03892 - - 0.00000000000000000000000000000000000000004639 154.0
CMS2_k127_1073288_9 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000001649 121.0
CMS2_k127_1074645_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.394e-257 804.0
CMS2_k127_1074645_1 ferric reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 545.0
CMS2_k127_1074645_10 SnoaL-like domain - - - 0.000000000000000000000000000000000001285 143.0
CMS2_k127_1074645_11 Propeptide PepSY amd peptidase M4 - - - 0.000000000000000000000000000001307 124.0
CMS2_k127_1074645_12 TPM domain - - - 0.00000000000000000000005017 112.0
CMS2_k127_1074645_13 Peptidase propeptide and YPEB domain - - - 0.0000000000000009758 81.0
CMS2_k127_1074645_15 CAAX protease self-immunity K07052 - - 0.0000000000003197 72.0
CMS2_k127_1074645_16 - - - - 0.0000000000357 66.0
CMS2_k127_1074645_17 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0003116 44.0
CMS2_k127_1074645_2 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 505.0
CMS2_k127_1074645_3 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 487.0
CMS2_k127_1074645_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 461.0
CMS2_k127_1074645_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 397.0
CMS2_k127_1074645_6 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 366.0
CMS2_k127_1074645_7 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 364.0
CMS2_k127_1074645_8 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 297.0
CMS2_k127_1074645_9 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
CMS2_k127_1080946_0 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 3.547e-274 864.0
CMS2_k127_1080946_1 Phosphate transport system permease protein K02038 - - 2.384e-248 777.0
CMS2_k127_1080946_2 COG4992 Ornithine acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 543.0
CMS2_k127_1080946_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 473.0
CMS2_k127_1080946_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 451.0
CMS2_k127_1080946_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 335.0
CMS2_k127_1080946_6 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 320.0
CMS2_k127_1080946_7 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
CMS2_k127_1080946_8 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000007431 169.0
CMS2_k127_1080946_9 - - - - 0.00000000000000000000000000000000000000008785 153.0
CMS2_k127_1083231_0 DEAD DEAH box K06877 - - 0.0 1232.0
CMS2_k127_1083231_1 COG0471 Di- and tricarboxylate transporters - - - 4.163e-259 811.0
CMS2_k127_1083231_2 S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 590.0
CMS2_k127_1083231_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 486.0
CMS2_k127_1083231_4 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 288.0
CMS2_k127_1083231_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009817 273.0
CMS2_k127_1083231_6 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008786 269.0
CMS2_k127_1109583_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 584.0
CMS2_k127_1109583_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 379.0
CMS2_k127_1109583_10 May be involved in the transport of PQQ or its precursor to the periplasm K06136,K06167 - 3.1.4.55 0.000000000000000000000007608 112.0
CMS2_k127_1109583_11 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000008676 95.0
CMS2_k127_1109583_12 - - - - 0.0000000004926 64.0
CMS2_k127_1109583_13 Multicopper oxidase K06324 - 1.16.3.3 0.00004156 46.0
CMS2_k127_1109583_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
CMS2_k127_1109583_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 362.0
CMS2_k127_1109583_4 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
CMS2_k127_1109583_5 - - - - 0.00000000000000000000000000000000000000000001058 171.0
CMS2_k127_1109583_6 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000002439 163.0
CMS2_k127_1109583_7 Protein of unknown function, DUF484 - - - 0.0000000000000000000000000000000000000001387 160.0
CMS2_k127_1109583_8 Glycine zipper - - - 0.000000000000000000000000000001643 130.0
CMS2_k127_1109583_9 belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.0000000000000000000000009078 107.0
CMS2_k127_114674_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.267e-279 869.0
CMS2_k127_114674_1 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 4.59e-239 755.0
CMS2_k127_114674_10 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 340.0
CMS2_k127_114674_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 328.0
CMS2_k127_114674_12 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 315.0
CMS2_k127_114674_13 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 301.0
CMS2_k127_114674_14 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 286.0
CMS2_k127_114674_15 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 267.0
CMS2_k127_114674_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 262.0
CMS2_k127_114674_17 Belongs to the DnaA family. HdA subfamily K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
CMS2_k127_114674_18 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000005679 221.0
CMS2_k127_114674_19 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000001055 218.0
CMS2_k127_114674_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 590.0
CMS2_k127_114674_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000003833 216.0
CMS2_k127_114674_21 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000001016 207.0
CMS2_k127_114674_22 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000161 197.0
CMS2_k127_114674_23 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000003331 185.0
CMS2_k127_114674_24 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000689 178.0
CMS2_k127_114674_25 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000001964 180.0
CMS2_k127_114674_26 Thioesterase superfamily K01075,K07107 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790 3.1.2.23 0.00000000000000000000000000000000000000000000002524 173.0
CMS2_k127_114674_27 transcriptional regulator K01420 - - 0.0000000000000000000000000000000000000000006035 168.0
CMS2_k127_114674_28 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000007724 164.0
CMS2_k127_114674_29 COG1393 Arsenate reductase and related proteins, glutaredoxin family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000001651 155.0
CMS2_k127_114674_3 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 567.0
CMS2_k127_114674_30 PFAM Biopolymer transport protein ExbD TolR K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000002587 158.0
CMS2_k127_114674_31 protein conserved in bacteria K09938 - - 0.0000000000000000000000000000000000000001098 165.0
CMS2_k127_114674_32 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18901 - - 0.0000000000000000000000000000000000000002249 159.0
CMS2_k127_114674_33 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000002667 156.0
CMS2_k127_114674_34 Rhomboid family - - - 0.000000000000000000000000000000000000001599 155.0
CMS2_k127_114674_35 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000001447 143.0
CMS2_k127_114674_36 LysM domain - - - 0.0000000000000000000000000000000001506 140.0
CMS2_k127_114674_37 TonB C terminal K03646 - - 0.00000000000000000000000000000001224 138.0
CMS2_k127_114674_38 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000008366 111.0
CMS2_k127_114674_39 acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000009514 101.0
CMS2_k127_114674_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 528.0
CMS2_k127_114674_40 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000002056 89.0
CMS2_k127_114674_42 - - - - 0.00000007001 59.0
CMS2_k127_114674_5 AIR synthase related protein, N-terminal domain K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 515.0
CMS2_k127_114674_6 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 512.0
CMS2_k127_114674_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 502.0
CMS2_k127_114674_8 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
CMS2_k127_114674_9 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 370.0
CMS2_k127_1165512_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 1.847e-212 666.0
CMS2_k127_1165512_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.393e-196 617.0
CMS2_k127_1165512_10 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 323.0
CMS2_k127_1165512_11 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 298.0
CMS2_k127_1165512_12 COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
CMS2_k127_1165512_13 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 286.0
CMS2_k127_1165512_14 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K02074,K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 269.0
CMS2_k127_1165512_15 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000927 258.0
CMS2_k127_1165512_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000002483 226.0
CMS2_k127_1165512_17 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000000000000006049 219.0
CMS2_k127_1165512_18 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000002524 213.0
CMS2_k127_1165512_19 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
CMS2_k127_1165512_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.486e-196 621.0
CMS2_k127_1165512_20 Iron--sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000000000000000000000000000000434 198.0
CMS2_k127_1165512_21 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000005427 185.0
CMS2_k127_1165512_22 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000002678 156.0
CMS2_k127_1165512_23 - - - - 0.0000000000000000000000000000000819 133.0
CMS2_k127_1165512_24 - - - - 0.0000000000000000000000000000009128 126.0
CMS2_k127_1165512_25 - - - - 0.000000009225 57.0
CMS2_k127_1165512_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 613.0
CMS2_k127_1165512_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 524.0
CMS2_k127_1165512_5 Acid phosphatase homologues K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 465.0
CMS2_k127_1165512_6 Chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 436.0
CMS2_k127_1165512_7 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 436.0
CMS2_k127_1165512_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 409.0
CMS2_k127_1165512_9 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 375.0
CMS2_k127_1183366_0 Dinitrogenase iron-molybdenum cofactor K02585 - - 1.775e-242 760.0
CMS2_k127_1183366_1 Fis Family K02584 - - 3.098e-214 676.0
CMS2_k127_1183366_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 342.0
CMS2_k127_1183366_11 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 307.0
CMS2_k127_1183366_12 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 310.0
CMS2_k127_1183366_13 peptidase K06992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
CMS2_k127_1183366_14 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000004192 237.0
CMS2_k127_1183366_15 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
CMS2_k127_1183366_16 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000002062 231.0
CMS2_k127_1183366_17 PFAM NifQ K15790 - - 0.00000000000000000000000000000000000000000000001414 179.0
CMS2_k127_1183366_18 - - - - 0.00000000000000000000000000000000000000000000003351 184.0
CMS2_k127_1183366_19 - - - - 0.000000000000000000000000000000000000000002383 170.0
CMS2_k127_1183366_2 TIGRFAM SagB-type dehydrogenase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 575.0
CMS2_k127_1183366_20 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000403 150.0
CMS2_k127_1183366_21 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000001133 149.0
CMS2_k127_1183366_22 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000001204 146.0
CMS2_k127_1183366_23 Ferredoxin - - - 0.000000000000000000000000000000000007049 138.0
CMS2_k127_1183366_24 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000339 119.0
CMS2_k127_1183366_25 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000007661 115.0
CMS2_k127_1183366_26 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000004543 114.0
CMS2_k127_1183366_27 NifZ domain K02597 - - 0.0000000000000000007872 89.0
CMS2_k127_1183366_28 YqjK-like protein - - - 0.00000000000004677 75.0
CMS2_k127_1183366_29 PFAM peptidase M4 thermolysin - - - 0.0000000000001038 83.0
CMS2_k127_1183366_3 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 568.0
CMS2_k127_1183366_30 Metallo-beta-lactamase superfamily - - - 0.000000000003251 68.0
CMS2_k127_1183366_31 - - - - 0.0000000001426 70.0
CMS2_k127_1183366_32 - - - - 0.000000004097 66.0
CMS2_k127_1183366_33 - - - - 0.0001428 53.0
CMS2_k127_1183366_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 474.0
CMS2_k127_1183366_5 nitrogen fixation negative regulator NifL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 483.0
CMS2_k127_1183366_6 Domains REC, sigma54 interaction, HTH8 K20919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 450.0
CMS2_k127_1183366_7 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 393.0
CMS2_k127_1183366_8 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 367.0
CMS2_k127_1183366_9 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 360.0
CMS2_k127_1228718_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 0.0 1168.0
CMS2_k127_1228718_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 571.0
CMS2_k127_1228718_10 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003702 249.0
CMS2_k127_1228718_11 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002658 248.0
CMS2_k127_1228718_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003868 223.0
CMS2_k127_1228718_13 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000001219 216.0
CMS2_k127_1228718_14 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000004163 211.0
CMS2_k127_1228718_15 TIGRFAM Diguanylate cyclase K13069 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000004288 201.0
CMS2_k127_1228718_16 protein histidine kinase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000002472 196.0
CMS2_k127_1228718_17 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000001777 163.0
CMS2_k127_1228718_18 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000001039 157.0
CMS2_k127_1228718_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 565.0
CMS2_k127_1228718_20 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000002706 133.0
CMS2_k127_1228718_21 DsrC like protein K11179 - - 0.0000000000000000000000000005512 117.0
CMS2_k127_1228718_22 Histidine kinase-like ATPases - - - 0.00000000000000000000000587 117.0
CMS2_k127_1228718_23 - - - - 0.0000000000000002255 79.0
CMS2_k127_1228718_24 Domain of unknown function (DUF3330) - - - 0.00000000001629 70.0
CMS2_k127_1228718_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 518.0
CMS2_k127_1228718_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 394.0
CMS2_k127_1228718_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 325.0
CMS2_k127_1228718_6 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 283.0
CMS2_k127_1228718_7 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004882 258.0
CMS2_k127_1228718_8 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002094 256.0
CMS2_k127_1228718_9 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003197 252.0
CMS2_k127_123980_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.294e-288 895.0
CMS2_k127_123980_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.064e-262 826.0
CMS2_k127_123980_10 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000006047 270.0
CMS2_k127_123980_11 Bacterial lipid A biosynthesis acyltransferase K02560 - 2.3.1.243 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 270.0
CMS2_k127_123980_12 Peptidase membrane zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
CMS2_k127_123980_13 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
CMS2_k127_123980_14 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005038 230.0
CMS2_k127_123980_15 SMART cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
CMS2_k127_123980_16 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
CMS2_k127_123980_17 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
CMS2_k127_123980_18 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001219 197.0
CMS2_k127_123980_19 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001096 192.0
CMS2_k127_123980_2 FecR protein - - - 1.689e-246 801.0
CMS2_k127_123980_20 Cell division protein K03591 - - 0.00000000000000000000000000000000001942 144.0
CMS2_k127_123980_22 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000008381 113.0
CMS2_k127_123980_23 Bacterial-like globin K06886 - - 0.00000000000000001184 87.0
CMS2_k127_123980_25 Zn-dependent protease with chaperone function - - - 0.00000001849 66.0
CMS2_k127_123980_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 557.0
CMS2_k127_123980_4 PFAM aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 501.0
CMS2_k127_123980_5 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 501.0
CMS2_k127_123980_6 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
CMS2_k127_123980_7 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 377.0
CMS2_k127_123980_8 Methyltransferase K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
CMS2_k127_123980_9 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 350.0
CMS2_k127_1255430_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 519.0
CMS2_k127_1255430_1 dna ligase K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 294.0
CMS2_k127_1255430_2 Nitroreductase K10679 GO:0000166,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018545,GO:0018973,GO:0018974,GO:0019326,GO:0019439,GO:0032553,GO:0036094,GO:0042537,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046256,GO:0046260,GO:0046263,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072490,GO:0072491,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.5.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 271.0
CMS2_k127_1255430_3 COG1051 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000006835 124.0
CMS2_k127_1255430_4 - - - - 0.000000000000000000000000000007207 126.0
CMS2_k127_1292834_0 Putative exonuclease SbcCD, C subunit - - - 0.0 1186.0
CMS2_k127_1292834_1 Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) K06957 - 2.3.1.193 2.44e-213 686.0
CMS2_k127_1292834_10 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000002911 183.0
CMS2_k127_1292834_11 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000473 185.0
CMS2_k127_1292834_12 Protein of unknown function (DUF2452) - - - 0.0000000000000000000000000000000000000000000003077 171.0
CMS2_k127_1292834_13 - - - - 0.0000000000000000000000000000000002386 139.0
CMS2_k127_1292834_14 - - - - 0.000000000000000000000000000003628 121.0
CMS2_k127_1292834_15 Protein of unknown function (DUF504) - - - 0.0000000000000000000000000002769 119.0
CMS2_k127_1292834_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 487.0
CMS2_k127_1292834_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 394.0
CMS2_k127_1292834_4 ZIP Zinc transporter K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008702 274.0
CMS2_k127_1292834_5 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000000000000000000007215 239.0
CMS2_k127_1292834_6 Uncharacterized protein conserved in bacteria C-term(DUF2220) - - - 0.00000000000000000000000000000000000000000000000000000000000000004087 236.0
CMS2_k127_1292834_7 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000000000000000000000001321 219.0
CMS2_k127_1292834_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001749 212.0
CMS2_k127_1292834_9 THUMP - - - 0.0000000000000000000000000000000000000000000000000001187 193.0
CMS2_k127_1304317_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1014.0
CMS2_k127_1304317_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.599e-227 732.0
CMS2_k127_1304317_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
CMS2_k127_1304317_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 546.0
CMS2_k127_1304317_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 456.0
CMS2_k127_1304317_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 427.0
CMS2_k127_1304317_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 377.0
CMS2_k127_1304317_6 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 372.0
CMS2_k127_1304317_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 342.0
CMS2_k127_1304317_8 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 331.0
CMS2_k127_1304317_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005681 261.0
CMS2_k127_1417028_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1416.0
CMS2_k127_1417028_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.324e-285 888.0
CMS2_k127_1417028_10 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 389.0
CMS2_k127_1417028_11 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
CMS2_k127_1417028_12 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 336.0
CMS2_k127_1417028_13 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
CMS2_k127_1417028_14 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 308.0
CMS2_k127_1417028_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 308.0
CMS2_k127_1417028_16 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003676 278.0
CMS2_k127_1417028_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
CMS2_k127_1417028_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000002648 241.0
CMS2_k127_1417028_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 228.0
CMS2_k127_1417028_2 ABC transporter transmembrane region K06147 - - 8.263e-248 779.0
CMS2_k127_1417028_20 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000001036 228.0
CMS2_k127_1417028_21 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000006786 222.0
CMS2_k127_1417028_22 - - - - 0.00000000000000000000000000000000000000000000000000002191 190.0
CMS2_k127_1417028_23 PFAM Amino acid-binding ACT K03567 - - 0.000000000000000000000000000000000000000000000000000214 190.0
CMS2_k127_1417028_24 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000008597 156.0
CMS2_k127_1417028_25 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.0000000000000000000000000000000000000009081 152.0
CMS2_k127_1417028_26 Belongs to the thioredoxin family K05838 - - 0.0000000000000000000000000000000000008361 142.0
CMS2_k127_1417028_27 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000429 97.0
CMS2_k127_1417028_28 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000005006 91.0
CMS2_k127_1417028_29 HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.0000000000000000007753 93.0
CMS2_k127_1417028_3 Thymidine phosphorylase K00758 - 2.4.2.4 6.147e-237 741.0
CMS2_k127_1417028_30 Regulatory protein, FmdB family - - - 0.00000000000000007637 82.0
CMS2_k127_1417028_31 Hydrogenase maturation protease - - - 0.00000000000003707 78.0
CMS2_k127_1417028_32 Cysteine-rich CPXCG - - - 0.0000000000001102 75.0
CMS2_k127_1417028_34 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000003899 48.0
CMS2_k127_1417028_4 Ion channel K10716 - - 1.583e-209 665.0
CMS2_k127_1417028_5 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 612.0
CMS2_k127_1417028_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 442.0
CMS2_k127_1417028_7 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 401.0
CMS2_k127_1417028_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 403.0
CMS2_k127_1417028_9 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 405.0
CMS2_k127_1467352_0 PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 1.83e-303 946.0
CMS2_k127_1467352_1 COG0210 Superfamily I DNA and RNA helicases K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 5.554e-302 942.0
CMS2_k127_1467352_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000001121 201.0
CMS2_k127_1467352_11 PFAM globin K06886 - - 0.00000000000000000000000000000000000000000000000000007141 188.0
CMS2_k127_1467352_12 Domain of unknown function (DUF4785) - - - 0.0000000000000000000000000000000000000000000000000003302 200.0
CMS2_k127_1467352_13 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000299 180.0
CMS2_k127_1467352_14 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.0000000000000000000000000000000000000000000001799 173.0
CMS2_k127_1467352_15 Uncharacterised protein family (UPF0149) - - - 0.000000000000000000000000000000000000000000001426 173.0
CMS2_k127_1467352_16 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000001671 168.0
CMS2_k127_1467352_17 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000003338 168.0
CMS2_k127_1467352_18 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000000000000002165 147.0
CMS2_k127_1467352_19 - - - - 0.00000000000000000000000000000000007544 139.0
CMS2_k127_1467352_2 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 5.001e-232 724.0
CMS2_k127_1467352_20 phosphoprotein phosphatase activity - - - 0.0000000000000001907 87.0
CMS2_k127_1467352_21 PFAM RNA recognition motif - - - 0.0000004489 54.0
CMS2_k127_1467352_22 - - - - 0.0000007406 56.0
CMS2_k127_1467352_23 - - - - 0.0002187 46.0
CMS2_k127_1467352_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 555.0
CMS2_k127_1467352_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 433.0
CMS2_k127_1467352_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 370.0
CMS2_k127_1467352_6 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
CMS2_k127_1467352_7 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 338.0
CMS2_k127_1467352_8 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006256 278.0
CMS2_k127_1467352_9 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001212 261.0
CMS2_k127_1468230_0 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 391.0
CMS2_k127_1468230_1 Stress responsive A/B Barrel Domain K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
CMS2_k127_1468230_2 hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 322.0
CMS2_k127_1468230_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000891 211.0
CMS2_k127_1468230_6 Alanine-zipper, major outer membrane lipoprotein - - - 0.00000002828 60.0
CMS2_k127_164440_0 P-type ATPase K17686 - 3.6.3.54 6.891e-266 839.0
CMS2_k127_164440_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.342e-233 729.0
CMS2_k127_164440_10 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002578 258.0
CMS2_k127_164440_11 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000009427 191.0
CMS2_k127_164440_12 Pfam Hemerythrin HHE - - - 0.00000000000000000000000000000000000000000000000001173 184.0
CMS2_k127_164440_13 - K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000003634 157.0
CMS2_k127_164440_14 epsilon subunit K02114 - - 0.00000000000000000000000000000000000006127 150.0
CMS2_k127_164440_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000006969 128.0
CMS2_k127_164440_16 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000000002722 127.0
CMS2_k127_164440_17 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000003249 116.0
CMS2_k127_164440_18 sulfur carrier activity K08363 - - 0.000000000000000001925 88.0
CMS2_k127_164440_19 Cupredoxin-like domain - - - 0.0004981 44.0
CMS2_k127_164440_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 499.0
CMS2_k127_164440_3 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 470.0
CMS2_k127_164440_4 radical SAM protein K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 454.0
CMS2_k127_164440_5 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 421.0
CMS2_k127_164440_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 398.0
CMS2_k127_164440_7 PFAM peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 359.0
CMS2_k127_164440_8 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 345.0
CMS2_k127_164440_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003357 286.0
CMS2_k127_17539_0 HI0933 family K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 567.0
CMS2_k127_17539_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005432 281.0
CMS2_k127_17539_2 Protein of unknown function (DUF1415) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006061 233.0
CMS2_k127_17539_3 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000001535 173.0
CMS2_k127_17539_4 MOSC domain - - - 0.00000000000000000000000000000000000000009552 156.0
CMS2_k127_17539_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000003835 57.0
CMS2_k127_1776935_0 Multicopper oxidase K22350 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 508.0
CMS2_k127_1776935_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 304.0
CMS2_k127_1776935_2 Integrase core domain K07482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004011 275.0
CMS2_k127_1776935_3 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001264 200.0
CMS2_k127_1776935_4 - - - - 0.00000000000000000000000000004954 123.0
CMS2_k127_1776935_5 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000002253 108.0
CMS2_k127_1794573_0 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 612.0
CMS2_k127_1794573_1 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001651 285.0
CMS2_k127_1794573_2 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000000000000000000000000000000001064 188.0
CMS2_k127_1794573_3 Domain of unknown function (DUF4398) - - - 0.0000000000002185 76.0
CMS2_k127_1897027_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1079.0
CMS2_k127_1897027_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 1.123e-266 847.0
CMS2_k127_1897027_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 428.0
CMS2_k127_1897027_11 Methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 419.0
CMS2_k127_1897027_12 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 417.0
CMS2_k127_1897027_13 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 413.0
CMS2_k127_1897027_14 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 352.0
CMS2_k127_1897027_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 338.0
CMS2_k127_1897027_16 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 336.0
CMS2_k127_1897027_17 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 313.0
CMS2_k127_1897027_18 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 312.0
CMS2_k127_1897027_19 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 304.0
CMS2_k127_1897027_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.241e-256 809.0
CMS2_k127_1897027_20 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007048 287.0
CMS2_k127_1897027_21 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008272 273.0
CMS2_k127_1897027_22 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001593 276.0
CMS2_k127_1897027_23 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003851 249.0
CMS2_k127_1897027_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004219 245.0
CMS2_k127_1897027_25 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000238 230.0
CMS2_k127_1897027_26 - - - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
CMS2_k127_1897027_27 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000001276 207.0
CMS2_k127_1897027_28 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000004382 201.0
CMS2_k127_1897027_29 - - - - 0.00000000000000000000000000000000000000000000000000004578 196.0
CMS2_k127_1897027_3 ABC transporter K06158 - - 2.951e-253 796.0
CMS2_k127_1897027_30 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000002542 190.0
CMS2_k127_1897027_31 PFAM ApaG domain protein K06195 - - 0.00000000000000000000000000000000000000000000000007104 180.0
CMS2_k127_1897027_32 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000000000004812 171.0
CMS2_k127_1897027_33 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000002869 177.0
CMS2_k127_1897027_34 PFAM SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000000025 168.0
CMS2_k127_1897027_35 - - - - 0.00000000000000000000000000000000005084 136.0
CMS2_k127_1897027_36 of the cupin superfamily K06995 - - 0.0000000000000000000000000000000001197 136.0
CMS2_k127_1897027_37 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000001792 124.0
CMS2_k127_1897027_38 pilin assembly protein - - - 0.000000000000000000000000000009146 121.0
CMS2_k127_1897027_39 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000001141 121.0
CMS2_k127_1897027_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.633e-234 728.0
CMS2_k127_1897027_40 SMART Cold shock protein K03704 - - 0.00000000000000000000000009439 108.0
CMS2_k127_1897027_41 Protein of unknown function (DUF465) - - - 0.000000000000000000000000204 109.0
CMS2_k127_1897027_42 PFAM VanZ - - - 0.00000000000000000004086 93.0
CMS2_k127_1897027_43 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000005052 86.0
CMS2_k127_1897027_44 Belongs to the SlyX family K03745 - - 0.00000004569 57.0
CMS2_k127_1897027_5 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.309e-197 620.0
CMS2_k127_1897027_6 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 528.0
CMS2_k127_1897027_7 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 529.0
CMS2_k127_1897027_8 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 514.0
CMS2_k127_1897027_9 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 439.0
CMS2_k127_1917943_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.695e-246 767.0
CMS2_k127_1917943_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.25e-239 749.0
CMS2_k127_1917943_10 pfam mofrl K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 371.0
CMS2_k127_1917943_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 359.0
CMS2_k127_1917943_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 338.0
CMS2_k127_1917943_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 324.0
CMS2_k127_1917943_14 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
CMS2_k127_1917943_15 FimV C-terminal K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 334.0
CMS2_k127_1917943_16 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009491 271.0
CMS2_k127_1917943_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001567 234.0
CMS2_k127_1917943_18 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000002582 194.0
CMS2_k127_1917943_19 Domain of unknown function (DUF1853) K09977 - - 0.00000000000000000000000000000000000000000000000006436 191.0
CMS2_k127_1917943_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.521e-217 678.0
CMS2_k127_1917943_20 Helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000003885 154.0
CMS2_k127_1917943_21 - - - - 0.000000000000000000000000000000000007354 145.0
CMS2_k127_1917943_22 Sporulation related domain K03749 - - 0.0000000000000000000000003035 112.0
CMS2_k127_1917943_23 Protein required for attachment to host cells - - - 0.00000000000000000000002324 104.0
CMS2_k127_1917943_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.093e-207 649.0
CMS2_k127_1917943_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 3.796e-194 613.0
CMS2_k127_1917943_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 580.0
CMS2_k127_1917943_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 443.0
CMS2_k127_1917943_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 434.0
CMS2_k127_1917943_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 372.0
CMS2_k127_1917943_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 368.0
CMS2_k127_1933375_0 5'-nucleotidase, C-terminal domain K17224 - - 4.28e-261 814.0
CMS2_k127_1933375_1 ABC transporter transmembrane region K06148 - - 8.606e-257 807.0
CMS2_k127_1933375_10 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 470.0
CMS2_k127_1933375_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 411.0
CMS2_k127_1933375_12 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 394.0
CMS2_k127_1933375_13 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 372.0
CMS2_k127_1933375_14 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
CMS2_k127_1933375_15 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004775 269.0
CMS2_k127_1933375_16 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000000000000000000001159 238.0
CMS2_k127_1933375_17 TadE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
CMS2_k127_1933375_18 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004114 232.0
CMS2_k127_1933375_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
CMS2_k127_1933375_2 His Kinase A (phosphoacceptor) domain K14986 - 2.7.13.3 1.324e-239 760.0
CMS2_k127_1933375_20 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000006112 207.0
CMS2_k127_1933375_21 TadE-like protein - - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
CMS2_k127_1933375_22 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000001556 194.0
CMS2_k127_1933375_24 COG3547 Transposase and inactivated derivatives - - - 0.00000000001618 68.0
CMS2_k127_1933375_25 Flp Fap pilin component K02651 - - 0.0000000007021 64.0
CMS2_k127_1933375_26 - - - - 0.000000007852 57.0
CMS2_k127_1933375_28 Nuclease-related domain - - - 0.000000513 59.0
CMS2_k127_1933375_29 - - - - 0.00001963 47.0
CMS2_k127_1933375_3 COG4962 Flp pilus assembly protein, ATPase CpaF K02283 - - 1.25e-233 730.0
CMS2_k127_1933375_4 cytochrome c biogenesis protein - - - 4.977e-230 723.0
CMS2_k127_1933375_5 ATPases associated with a variety of cellular activities - - - 7.486e-221 694.0
CMS2_k127_1933375_6 Belongs to the GSP D family K02280 - - 1.675e-213 675.0
CMS2_k127_1933375_7 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 575.0
CMS2_k127_1933375_8 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 526.0
CMS2_k127_1933375_9 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
CMS2_k127_2023296_0 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 507.0
CMS2_k127_2023296_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 383.0
CMS2_k127_2023296_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
CMS2_k127_2023296_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 338.0
CMS2_k127_2023296_4 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
CMS2_k127_2023296_5 pfam ammecr1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001429 232.0
CMS2_k127_2023296_6 protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000000000000000004229 221.0
CMS2_k127_2023296_7 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000004098 121.0
CMS2_k127_2023296_8 Cytochrome c - - - 0.000000000000000000000327 99.0
CMS2_k127_2023296_9 Belongs to the ompA family K03286 - - 0.00000000000008175 76.0
CMS2_k127_2107672_0 AcrB/AcrD/AcrF family K18138 - - 0.0 1477.0
CMS2_k127_2107672_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 477.0
CMS2_k127_2107672_2 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 391.0
CMS2_k127_2107672_3 PFAM regulatory protein TetR K03577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003973 248.0
CMS2_k127_2107672_4 Protein of unknown function (DUF1207) - - - 0.00000000000000000000000000000000000001106 156.0
CMS2_k127_2107672_5 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000004261 145.0
CMS2_k127_2107672_7 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000523 77.0
CMS2_k127_2109456_0 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 450.0
CMS2_k127_2109456_1 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001828 281.0
CMS2_k127_2109456_2 - - - - 0.00000000000000000000000000000000000000000000000000000000007619 214.0
CMS2_k127_2109456_3 response regulator receiver - - - 0.00000000000000000000000000000000000000000000003932 177.0
CMS2_k127_2109456_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.000001232 50.0
CMS2_k127_2109456_5 Transposase IS66 family K07484 - - 0.00000508 54.0
CMS2_k127_2109456_6 Transposase IS66 family - - - 0.00002632 53.0
CMS2_k127_2121358_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0 1825.0
CMS2_k127_2121358_1 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.0 1610.0
CMS2_k127_2121358_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1073.0
CMS2_k127_2121358_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1004.0
CMS2_k127_2121358_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.778e-309 960.0
CMS2_k127_2121358_5 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 2.86e-252 794.0
CMS2_k127_2121358_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 587.0
CMS2_k127_2121358_7 Alkaline and neutral invertase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 472.0
CMS2_k127_2121358_8 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000005091 65.0
CMS2_k127_2122188_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.427e-279 864.0
CMS2_k127_2122188_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.389e-276 860.0
CMS2_k127_2122188_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 433.0
CMS2_k127_2122188_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 394.0
CMS2_k127_2122188_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 370.0
CMS2_k127_2122188_13 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002302 285.0
CMS2_k127_2122188_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000004298 263.0
CMS2_k127_2122188_15 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000008621 216.0
CMS2_k127_2122188_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000008463 207.0
CMS2_k127_2122188_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000002033 196.0
CMS2_k127_2122188_18 PFAM Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000009579 194.0
CMS2_k127_2122188_19 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000223 178.0
CMS2_k127_2122188_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.453e-266 822.0
CMS2_k127_2122188_20 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000003594 162.0
CMS2_k127_2122188_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000209 132.0
CMS2_k127_2122188_22 ATP synthase I chain K02116 - - 0.0001623 49.0
CMS2_k127_2122188_3 signal transduction histidine kinase - - - 1.264e-230 735.0
CMS2_k127_2122188_4 PFAM TrkA-N domain K03499 - - 8.551e-227 709.0
CMS2_k127_2122188_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 1.808e-217 685.0
CMS2_k127_2122188_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 561.0
CMS2_k127_2122188_7 response regulator receiver K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 511.0
CMS2_k127_2122188_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 475.0
CMS2_k127_2122188_9 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 434.0
CMS2_k127_2123102_0 Polysaccharide biosynthesis/export protein - - - 8.241e-230 725.0
CMS2_k127_2123102_1 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 605.0
CMS2_k127_2123102_2 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 535.0
CMS2_k127_2123102_3 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 513.0
CMS2_k127_2123102_4 COG3524 Capsule polysaccharide export protein K10107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 416.0
CMS2_k127_2123102_5 PFAM ABC transporter related K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 324.0
CMS2_k127_2123102_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 326.0
CMS2_k127_2123102_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 314.0
CMS2_k127_2123102_8 Transport permease protein K09688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 270.0
CMS2_k127_2123102_9 - - - - 0.0000000000000000000000119 105.0
CMS2_k127_2143539_0 OmpA family - - - 0.0 2273.0
CMS2_k127_2143539_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1500.0
CMS2_k127_2143539_10 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.508e-229 716.0
CMS2_k127_2143539_11 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.243e-214 670.0
CMS2_k127_2143539_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 3.924e-211 662.0
CMS2_k127_2143539_13 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.255e-200 631.0
CMS2_k127_2143539_14 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 4.605e-200 631.0
CMS2_k127_2143539_15 ATPase (AAA K07478 - - 1.205e-196 623.0
CMS2_k127_2143539_16 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 596.0
CMS2_k127_2143539_17 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 592.0
CMS2_k127_2143539_18 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 580.0
CMS2_k127_2143539_19 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 574.0
CMS2_k127_2143539_2 Domain of unknown function DUF11 - - - 0.0 1500.0
CMS2_k127_2143539_20 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
CMS2_k127_2143539_21 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 512.0
CMS2_k127_2143539_22 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 499.0
CMS2_k127_2143539_23 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 484.0
CMS2_k127_2143539_24 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 485.0
CMS2_k127_2143539_25 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 467.0
CMS2_k127_2143539_26 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 464.0
CMS2_k127_2143539_27 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 463.0
CMS2_k127_2143539_28 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 465.0
CMS2_k127_2143539_29 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
CMS2_k127_2143539_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1315.0
CMS2_k127_2143539_30 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 437.0
CMS2_k127_2143539_31 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 383.0
CMS2_k127_2143539_32 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 386.0
CMS2_k127_2143539_33 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
CMS2_k127_2143539_34 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 357.0
CMS2_k127_2143539_35 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 351.0
CMS2_k127_2143539_36 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
CMS2_k127_2143539_37 pfam php K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 347.0
CMS2_k127_2143539_38 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 349.0
CMS2_k127_2143539_39 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 352.0
CMS2_k127_2143539_4 UPF0313 protein - - - 0.0 1084.0
CMS2_k127_2143539_40 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 329.0
CMS2_k127_2143539_41 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
CMS2_k127_2143539_42 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 314.0
CMS2_k127_2143539_43 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 318.0
CMS2_k127_2143539_44 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 304.0
CMS2_k127_2143539_45 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 301.0
CMS2_k127_2143539_46 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 315.0
CMS2_k127_2143539_47 PFAM HhH-GPD K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009454 277.0
CMS2_k127_2143539_48 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007167 273.0
CMS2_k127_2143539_49 HAD-hyrolase-like K01091,K22292 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564 3.1.3.105,3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000225 271.0
CMS2_k127_2143539_5 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1075.0
CMS2_k127_2143539_50 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
CMS2_k127_2143539_51 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
CMS2_k127_2143539_52 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002384 265.0
CMS2_k127_2143539_53 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
CMS2_k127_2143539_54 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 263.0
CMS2_k127_2143539_55 probably involved in intracellular septation K06190 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
CMS2_k127_2143539_56 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006316 241.0
CMS2_k127_2143539_57 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
CMS2_k127_2143539_58 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
CMS2_k127_2143539_59 PFAM Rhodanese-like - - - 0.0000000000000000000000000000000000000000000000000000000000007498 214.0
CMS2_k127_2143539_6 cell division protein K03466 - - 1.9e-284 893.0
CMS2_k127_2143539_60 High frequency lysogenization protein HflD homolog K07153 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - 0.000000000000000000000000000000000000000000000000000000000381 209.0
CMS2_k127_2143539_61 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000004609 208.0
CMS2_k127_2143539_62 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000838 187.0
CMS2_k127_2143539_63 MafB19-like deaminase K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000146 184.0
CMS2_k127_2143539_64 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000009673 180.0
CMS2_k127_2143539_65 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000002872 169.0
CMS2_k127_2143539_66 YCII-related domain K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000003639 168.0
CMS2_k127_2143539_67 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000664 175.0
CMS2_k127_2143539_68 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000000000000000000008018 165.0
CMS2_k127_2143539_7 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - 3.62e-284 882.0
CMS2_k127_2143539_70 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000001105 156.0
CMS2_k127_2143539_71 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000001216 138.0
CMS2_k127_2143539_72 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000001275 125.0
CMS2_k127_2143539_73 Peptidase S24-like - - - 0.00000000000000000000000000005071 119.0
CMS2_k127_2143539_74 - - - - 0.0000000000000000000000000002461 117.0
CMS2_k127_2143539_75 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000003438 100.0
CMS2_k127_2143539_76 TIGRFAM cold shock domain protein CspD K03704 - - 0.00000000000000000006548 91.0
CMS2_k127_2143539_77 competence protein ComEA K02237 - - 0.00000000000000004885 85.0
CMS2_k127_2143539_78 - - - - 0.000000000000005852 81.0
CMS2_k127_2143539_79 - - - - 0.0000000000005538 75.0
CMS2_k127_2143539_8 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.792e-257 812.0
CMS2_k127_2143539_80 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000004947 66.0
CMS2_k127_2143539_81 Belongs to the bacterial histone-like protein family - - - 0.0000000002795 73.0
CMS2_k127_2143539_82 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000001889 65.0
CMS2_k127_2143539_83 Transposase IS200 like K07491 - - 0.0000002405 55.0
CMS2_k127_2143539_84 Lysin motif - - - 0.0005267 53.0
CMS2_k127_2143539_9 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 1.845e-232 737.0
CMS2_k127_2161065_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 406.0
CMS2_k127_2161065_1 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002673 269.0
CMS2_k127_2161065_2 - - - - 0.000000000000000000000000000000000000122 148.0
CMS2_k127_2161065_3 PFAM RNA recognition motif - - - 0.0000000000000000000000000000000000005185 141.0
CMS2_k127_2161065_4 COG3209 Rhs family protein - - - 0.0000000000000000000000005566 108.0
CMS2_k127_2161065_5 cold-shock protein K03704 - - 0.0000000001891 61.0
CMS2_k127_2173424_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.407e-298 929.0
CMS2_k127_2173424_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 2.045e-281 882.0
CMS2_k127_2173424_10 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
CMS2_k127_2173424_11 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 301.0
CMS2_k127_2173424_12 PFAM YicC-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 301.0
CMS2_k127_2173424_13 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
CMS2_k127_2173424_14 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
CMS2_k127_2173424_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
CMS2_k127_2173424_16 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
CMS2_k127_2173424_17 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005611 256.0
CMS2_k127_2173424_18 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000001785 246.0
CMS2_k127_2173424_19 Competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000546 239.0
CMS2_k127_2173424_2 Bacterial protein of unknown function (DUF839) K07093 - - 2.826e-197 630.0
CMS2_k127_2173424_20 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000392 233.0
CMS2_k127_2173424_21 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000000001506 228.0
CMS2_k127_2173424_22 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000004543 225.0
CMS2_k127_2173424_23 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.00000000000000000000000000000000000000000000005378 176.0
CMS2_k127_2173424_24 - - - - 0.0000000000000000000000000000000000000000491 158.0
CMS2_k127_2173424_25 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000002534 161.0
CMS2_k127_2173424_26 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000001032 150.0
CMS2_k127_2173424_27 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000001231 113.0
CMS2_k127_2173424_28 Belongs to the frataxin family K06202 - - 0.000000000000000000000000001587 126.0
CMS2_k127_2173424_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 607.0
CMS2_k127_2173424_30 MerR HTH family regulatory protein K18997 - - 0.0000000000000000000004336 100.0
CMS2_k127_2173424_31 rho-dependent transcription termination K19000 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000007877 64.0
CMS2_k127_2173424_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 524.0
CMS2_k127_2173424_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 494.0
CMS2_k127_2173424_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 453.0
CMS2_k127_2173424_7 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 429.0
CMS2_k127_2173424_8 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 374.0
CMS2_k127_2173424_9 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 377.0
CMS2_k127_2177878_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 4.4e-323 1003.0
CMS2_k127_2177878_1 von Willebrand factor (vWF) type A domain K02448 - - 1.361e-265 835.0
CMS2_k127_2177878_10 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000001564 152.0
CMS2_k127_2177878_2 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.111e-202 635.0
CMS2_k127_2177878_3 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 520.0
CMS2_k127_2177878_4 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 447.0
CMS2_k127_2177878_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 447.0
CMS2_k127_2177878_6 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
CMS2_k127_2177878_7 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
CMS2_k127_2177878_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003526 255.0
CMS2_k127_2177878_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000003963 156.0
CMS2_k127_2178116_0 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 402.0
CMS2_k127_2178116_1 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 372.0
CMS2_k127_2178116_2 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
CMS2_k127_2178116_3 nucleoid-associated protein K06899 - - 0.000000000000000000000000002469 120.0
CMS2_k127_2179347_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 6.409e-208 658.0
CMS2_k127_2179347_1 Radical SAM - - - 9.41e-198 628.0
CMS2_k127_2179347_11 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000006662 98.0
CMS2_k127_2179347_12 - - - - 0.000000000000001411 82.0
CMS2_k127_2179347_13 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.0000000000001162 72.0
CMS2_k127_2179347_14 - - - - 0.00000001552 59.0
CMS2_k127_2179347_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 445.0
CMS2_k127_2179347_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
CMS2_k127_2179347_4 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 381.0
CMS2_k127_2179347_5 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
CMS2_k127_2179347_6 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 335.0
CMS2_k127_2179347_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
CMS2_k127_2179347_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
CMS2_k127_2179347_9 Protein of unknown function (DUF559) K03427 - 2.1.1.72 0.0000000000000000000000000000000000000002571 153.0
CMS2_k127_2200582_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1075.0
CMS2_k127_2200582_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 2.558e-222 700.0
CMS2_k127_2200582_10 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000003588 232.0
CMS2_k127_2200582_11 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000002245 214.0
CMS2_k127_2200582_12 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001702 185.0
CMS2_k127_2200582_13 Clan AA aspartic protease K06985 - - 0.00000000000000000000000000000000000000000000000000379 188.0
CMS2_k127_2200582_14 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000005928 182.0
CMS2_k127_2200582_15 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.000000000000000000000000000000000000000000000002763 183.0
CMS2_k127_2200582_16 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000001093 135.0
CMS2_k127_2200582_17 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000002444 106.0
CMS2_k127_2200582_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000001286 86.0
CMS2_k127_2200582_19 - - - - 0.00000000000000995 78.0
CMS2_k127_2200582_2 PFAM sodium alanine symporter K03310 - - 2.719e-198 626.0
CMS2_k127_2200582_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008965 414.0
CMS2_k127_2200582_4 Aminotransferase class I and II K00817,K02225 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 400.0
CMS2_k127_2200582_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 342.0
CMS2_k127_2200582_6 COG2202 FOG PAS PAC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 330.0
CMS2_k127_2200582_7 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 319.0
CMS2_k127_2200582_8 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
CMS2_k127_2200582_9 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000004218 239.0
CMS2_k127_2270785_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1124.0
CMS2_k127_2270785_1 CoA binding domain - - - 0.0 1123.0
CMS2_k127_2270785_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
CMS2_k127_2270785_11 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002564 232.0
CMS2_k127_2270785_12 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000008411 127.0
CMS2_k127_2270785_2 Na H antiporter - - - 1.159e-195 621.0
CMS2_k127_2270785_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 581.0
CMS2_k127_2270785_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 538.0
CMS2_k127_2270785_5 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 401.0
CMS2_k127_2270785_6 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 325.0
CMS2_k127_2270785_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
CMS2_k127_2270785_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
CMS2_k127_2270785_9 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
CMS2_k127_2316311_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1342.0
CMS2_k127_2316311_1 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 378.0
CMS2_k127_2316311_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 266.0
CMS2_k127_2316311_3 Lytic transglycolase K20628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001513 247.0
CMS2_k127_2316311_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000001558 217.0
CMS2_k127_2316311_5 AefR-like transcriptional repressor, C-terminal region K18301 - - 0.000000000000000000000000000000000000000000005302 170.0
CMS2_k127_2316311_6 Outer membrane protein beta-barrel domain - - - 0.000000000000000000003214 102.0
CMS2_k127_2316311_7 COG1943 Transposase and inactivated derivatives - - - 0.000000000000002557 76.0
CMS2_k127_2316311_8 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.45 0.00000000007268 62.0
CMS2_k127_233587_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.72e-216 681.0
CMS2_k127_233587_1 membrane-anchored protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 370.0
CMS2_k127_2349082_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.278e-219 690.0
CMS2_k127_2349082_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 557.0
CMS2_k127_2349082_2 Anthranilate synthase component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 520.0
CMS2_k127_2349082_3 catalyzes the conversion of K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 396.0
CMS2_k127_2349082_4 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000006391 202.0
CMS2_k127_2349082_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000001722 161.0
CMS2_k127_2441275_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1183.0
CMS2_k127_2441275_1 TonB dependent receptor - - - 1.332e-269 846.0
CMS2_k127_2441275_10 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000001998 158.0
CMS2_k127_2441275_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000009242 143.0
CMS2_k127_2441275_12 - - - - 0.000000000000000000000000000000000005542 148.0
CMS2_k127_2441275_13 AhpC/TSA family - - - 0.00000000000000000000000000000000005974 139.0
CMS2_k127_2441275_14 protein conserved in bacteria K09796 - - 0.000000000000000000000001146 109.0
CMS2_k127_2441275_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000002667 100.0
CMS2_k127_2441275_18 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000001445 87.0
CMS2_k127_2441275_19 - - - - 0.00001035 48.0
CMS2_k127_2441275_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.159e-221 691.0
CMS2_k127_2441275_3 receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 489.0
CMS2_k127_2441275_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 448.0
CMS2_k127_2441275_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 420.0
CMS2_k127_2441275_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 419.0
CMS2_k127_2441275_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 401.0
CMS2_k127_2441275_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 344.0
CMS2_k127_2441275_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
CMS2_k127_2489192_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1245.0
CMS2_k127_2489192_1 Bifunctional transglycosylase second domain K05365 - 2.4.1.129,3.4.16.4 5.905e-272 858.0
CMS2_k127_2489192_10 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 467.0
CMS2_k127_2489192_11 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 364.0
CMS2_k127_2489192_12 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 357.0
CMS2_k127_2489192_13 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 346.0
CMS2_k127_2489192_14 phosphoesterase DHHA1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 332.0
CMS2_k127_2489192_15 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 261.0
CMS2_k127_2489192_16 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
CMS2_k127_2489192_17 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000127 254.0
CMS2_k127_2489192_18 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000003263 229.0
CMS2_k127_2489192_19 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
CMS2_k127_2489192_2 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 - - 3.505e-203 649.0
CMS2_k127_2489192_20 - - - - 0.0000000000000000000000000000000000000000000000000002667 189.0
CMS2_k127_2489192_21 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000007917 174.0
CMS2_k127_2489192_22 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000001885 174.0
CMS2_k127_2489192_23 Bacterial SH3 domain homologues K07184 - - 0.0000000000000000000000000000000000000001607 158.0
CMS2_k127_2489192_24 - - - - 0.000000000000000000000000000000003843 136.0
CMS2_k127_2489192_25 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003538 128.0
CMS2_k127_2489192_26 Protein of unknown function (DUF3579) - - - 0.00000000000000000006552 94.0
CMS2_k127_2489192_27 - - - - 0.00000000001548 65.0
CMS2_k127_2489192_28 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000003089 70.0
CMS2_k127_2489192_29 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000001019 63.0
CMS2_k127_2489192_3 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 6.83e-201 639.0
CMS2_k127_2489192_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 602.0
CMS2_k127_2489192_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 562.0
CMS2_k127_2489192_6 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 520.0
CMS2_k127_2489192_7 binding-protein-dependent transport systems inner membrane component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 514.0
CMS2_k127_2489192_8 PFAM Binding-protein-dependent transport system inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 510.0
CMS2_k127_2489192_9 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 483.0
CMS2_k127_2612173_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1167.0
CMS2_k127_2612173_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 9.746e-305 970.0
CMS2_k127_2612173_10 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 586.0
CMS2_k127_2612173_11 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 527.0
CMS2_k127_2612173_12 Putative metallopeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 527.0
CMS2_k127_2612173_13 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 521.0
CMS2_k127_2612173_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 524.0
CMS2_k127_2612173_15 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 508.0
CMS2_k127_2612173_16 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 514.0
CMS2_k127_2612173_17 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 482.0
CMS2_k127_2612173_18 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 470.0
CMS2_k127_2612173_19 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 454.0
CMS2_k127_2612173_2 Molecular chaperone. Has ATPase activity K04079 - - 1.85e-300 932.0
CMS2_k127_2612173_20 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 404.0
CMS2_k127_2612173_21 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 407.0
CMS2_k127_2612173_22 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 402.0
CMS2_k127_2612173_23 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 398.0
CMS2_k127_2612173_24 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 394.0
CMS2_k127_2612173_25 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 373.0
CMS2_k127_2612173_26 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 357.0
CMS2_k127_2612173_27 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 344.0
CMS2_k127_2612173_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 340.0
CMS2_k127_2612173_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 5.633e-299 934.0
CMS2_k127_2612173_30 PFAM pfkB family carbohydrate kinase K00846 - 2.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 306.0
CMS2_k127_2612173_31 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 302.0
CMS2_k127_2612173_32 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 282.0
CMS2_k127_2612173_33 cAMP phosphodiesterases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
CMS2_k127_2612173_34 PFAM Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001719 277.0
CMS2_k127_2612173_35 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000076 259.0
CMS2_k127_2612173_36 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003779 240.0
CMS2_k127_2612173_37 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
CMS2_k127_2612173_38 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000002344 240.0
CMS2_k127_2612173_39 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000005647 234.0
CMS2_k127_2612173_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.055e-251 786.0
CMS2_k127_2612173_40 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000001593 214.0
CMS2_k127_2612173_41 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000001592 204.0
CMS2_k127_2612173_42 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000001328 199.0
CMS2_k127_2612173_43 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000001822 198.0
CMS2_k127_2612173_44 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
CMS2_k127_2612173_45 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 0.000000000000000000000000000000000000000000000000000000168 204.0
CMS2_k127_2612173_46 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001891 197.0
CMS2_k127_2612173_47 pfam nudix K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000233 190.0
CMS2_k127_2612173_48 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000004005 184.0
CMS2_k127_2612173_49 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000001942 182.0
CMS2_k127_2612173_5 double-strand break repair protein AddB K16899 - 3.6.4.12 6.976e-248 797.0
CMS2_k127_2612173_50 possibly involved in cell wall synthesis K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000005466 182.0
CMS2_k127_2612173_51 membrane - - - 0.0000000000000000000000000000000000000000000005432 178.0
CMS2_k127_2612173_52 NUDIX domain K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000001003 160.0
CMS2_k127_2612173_53 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000003323 156.0
CMS2_k127_2612173_54 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000000000001854 145.0
CMS2_k127_2612173_55 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001029 139.0
CMS2_k127_2612173_56 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000003598 136.0
CMS2_k127_2612173_57 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000004233 136.0
CMS2_k127_2612173_58 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000005865 135.0
CMS2_k127_2612173_59 NlpC/P60 family - - - 0.00000000000000000000000000000001476 134.0
CMS2_k127_2612173_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.128e-217 681.0
CMS2_k127_2612173_60 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000001858 128.0
CMS2_k127_2612173_61 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000002386 118.0
CMS2_k127_2612173_62 PFAM CHAD domain containing protein - - - 0.000000000000000000005111 104.0
CMS2_k127_2612173_63 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000009071 86.0
CMS2_k127_2612173_64 protein conserved in bacteria K09937 - - 0.0000000001017 64.0
CMS2_k127_2612173_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 5.677e-214 673.0
CMS2_k127_2612173_8 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.331e-212 666.0
CMS2_k127_2612173_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 6.335e-194 614.0
CMS2_k127_2639232_0 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 440.0
CMS2_k127_2639232_1 ABC transporter ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 376.0
CMS2_k127_2639232_2 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001559 247.0
CMS2_k127_2639232_3 transport system, auxiliary component K18480 - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
CMS2_k127_2639232_4 AAA domain - - - 0.00000000000000000000000000000000000000000000003308 173.0
CMS2_k127_2675977_0 - - - - 0.0 1511.0
CMS2_k127_2675977_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 591.0
CMS2_k127_2675977_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001162 230.0
CMS2_k127_2698089_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2217.0
CMS2_k127_2698089_1 nitrate nitrite transporter K02575 - - 0.0 1002.0
CMS2_k127_2698089_10 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000000000000000007755 208.0
CMS2_k127_2698089_11 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000003272 172.0
CMS2_k127_2698089_2 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 7.195e-284 878.0
CMS2_k127_2698089_3 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 604.0
CMS2_k127_2698089_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 532.0
CMS2_k127_2698089_5 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 448.0
CMS2_k127_2698089_6 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 439.0
CMS2_k127_2698089_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 389.0
CMS2_k127_2698089_8 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 329.0
CMS2_k127_2698089_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 297.0
CMS2_k127_2708046_0 Tetratricopeptide repeat - - - 0.0 1142.0
CMS2_k127_2708046_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.258e-283 885.0
CMS2_k127_2708046_10 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000000000003035 110.0
CMS2_k127_2708046_11 - - - - 0.0000000000000000003696 91.0
CMS2_k127_2708046_2 Tetratricopeptide repeat - - - 3.294e-230 730.0
CMS2_k127_2708046_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 395.0
CMS2_k127_2708046_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 355.0
CMS2_k127_2708046_5 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002253 275.0
CMS2_k127_2708046_6 - - - - 0.00000000000000000000000000000000000000000000000000008446 191.0
CMS2_k127_2708046_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000003498 182.0
CMS2_k127_2708046_8 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000001829 164.0
CMS2_k127_2708046_9 biopolymer transport protein - - - 0.000000000000000000000000000000000000000001342 161.0
CMS2_k127_2725664_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1181.0
CMS2_k127_2725664_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0 1074.0
CMS2_k127_2725664_10 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 414.0
CMS2_k127_2725664_11 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 349.0
CMS2_k127_2725664_12 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 338.0
CMS2_k127_2725664_13 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 342.0
CMS2_k127_2725664_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 333.0
CMS2_k127_2725664_15 membrane GTPase involved in stress response K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 328.0
CMS2_k127_2725664_16 Transcriptional regulator K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 315.0
CMS2_k127_2725664_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 300.0
CMS2_k127_2725664_18 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 301.0
CMS2_k127_2725664_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 289.0
CMS2_k127_2725664_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.733e-286 892.0
CMS2_k127_2725664_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
CMS2_k127_2725664_21 PFAM NADH Ubiquinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001151 278.0
CMS2_k127_2725664_22 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000001775 214.0
CMS2_k127_2725664_23 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000000397 206.0
CMS2_k127_2725664_24 - - - - 0.00000000000000000000000000000000000000000000000000003937 194.0
CMS2_k127_2725664_26 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001824 170.0
CMS2_k127_2725664_27 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000001963 169.0
CMS2_k127_2725664_28 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000006124 173.0
CMS2_k127_2725664_29 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000001793 167.0
CMS2_k127_2725664_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.147e-269 832.0
CMS2_k127_2725664_30 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000008588 139.0
CMS2_k127_2725664_31 - - - - 0.0000000000000000000000000000000003493 138.0
CMS2_k127_2725664_32 PFAM FixH - - - 0.00000000000000000000000000000000349 136.0
CMS2_k127_2725664_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000003483 123.0
CMS2_k127_2725664_34 XRE family transcriptional regulator - - - 0.00000000000000000000000000004711 117.0
CMS2_k127_2725664_35 organic phosphonate transport K02044 - - 0.000000000000000000000000003654 122.0
CMS2_k127_2725664_36 luxR family - - - 0.0000000000000000000006242 103.0
CMS2_k127_2725664_37 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000000000000000002035 90.0
CMS2_k127_2725664_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000889 87.0
CMS2_k127_2725664_39 PFAM Integrase - - - 0.0000000000000002177 80.0
CMS2_k127_2725664_4 PFAM NADH Ubiquinone plastoquinone K12141 - - 4.219e-252 784.0
CMS2_k127_2725664_40 PFAM cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000003262 81.0
CMS2_k127_2725664_5 NADH dehydrogenase - - - 2.376e-203 656.0
CMS2_k127_2725664_6 TIGRFAM cytochrome c oxidase accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 608.0
CMS2_k127_2725664_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 496.0
CMS2_k127_2725664_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 452.0
CMS2_k127_2725664_9 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 449.0
CMS2_k127_277134_0 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 467.0
CMS2_k127_277134_1 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000009765 181.0
CMS2_k127_277134_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000907 159.0
CMS2_k127_277134_3 - - - - 0.000000000000000000009366 96.0
CMS2_k127_277134_4 Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC K02016,K06858 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - 0.0000000000001888 71.0
CMS2_k127_278127_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.374e-215 677.0
CMS2_k127_278127_1 PFAM Radical SAM K04069 - 1.97.1.4 3.579e-202 633.0
CMS2_k127_278127_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.061e-197 619.0
CMS2_k127_278127_3 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
CMS2_k127_278127_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 383.0
CMS2_k127_278127_5 May be involved in the biosynthesis of molybdopterin K03638,K03831 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 295.0
CMS2_k127_278127_6 Memo-like protein K06990 - - 0.0000000000000000000000000000003197 123.0
CMS2_k127_278127_7 - - - - 0.000000000000000001162 90.0
CMS2_k127_2946076_0 Peptidase, M16 K06972 - - 0.0 1177.0
CMS2_k127_2946076_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.199e-292 906.0
CMS2_k127_2946076_10 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 404.0
CMS2_k127_2946076_11 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 353.0
CMS2_k127_2946076_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 334.0
CMS2_k127_2946076_13 Domain of unknown function (DUF4350) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 325.0
CMS2_k127_2946076_14 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 296.0
CMS2_k127_2946076_15 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 273.0
CMS2_k127_2946076_16 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002061 258.0
CMS2_k127_2946076_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002574 242.0
CMS2_k127_2946076_18 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000004877 192.0
CMS2_k127_2946076_19 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003104 168.0
CMS2_k127_2946076_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.702e-269 837.0
CMS2_k127_2946076_20 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000004153 111.0
CMS2_k127_2946076_21 Cytochrome c554 and c-prime - - - 0.00000000000000001619 90.0
CMS2_k127_2946076_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.008e-267 831.0
CMS2_k127_2946076_4 Diguanylate cyclase - - - 6.084e-200 654.0
CMS2_k127_2946076_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 600.0
CMS2_k127_2946076_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 559.0
CMS2_k127_2946076_7 ATPase, AAA K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 516.0
CMS2_k127_2946076_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 521.0
CMS2_k127_2946076_9 pfam abc K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 410.0
CMS2_k127_2983782_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 574.0
CMS2_k127_2983782_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 493.0
CMS2_k127_2983782_2 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 369.0
CMS2_k127_2983782_3 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000001165 200.0
CMS2_k127_2983782_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000007908 166.0
CMS2_k127_2983782_5 Modulates RecA activity K03565 - - 0.00000000000000000000000000004708 123.0
CMS2_k127_2983782_6 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000002054 98.0
CMS2_k127_3014642_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 579.0
CMS2_k127_3014642_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 512.0
CMS2_k127_3061362_0 PFAM peptidase K08303 - - 2.042e-218 684.0
CMS2_k127_3061362_1 PFAM phosphate transporter K03306 - - 4.376e-194 612.0
CMS2_k127_3061362_10 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000003345 192.0
CMS2_k127_3061362_11 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000001005 171.0
CMS2_k127_3061362_12 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000002534 139.0
CMS2_k127_3061362_13 GDYXXLXY protein - - - 0.00000000000000000000000000003496 130.0
CMS2_k127_3061362_14 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.000000000000000003071 95.0
CMS2_k127_3061362_15 Chemoreceptor zinc-binding domain - - - 0.00000000000000003285 86.0
CMS2_k127_3061362_16 Chemoreceptor zinc-binding domain - - - 0.0000000000000859 74.0
CMS2_k127_3061362_17 Cytochrome c554 and c-prime - - - 0.0008767 48.0
CMS2_k127_3061362_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 532.0
CMS2_k127_3061362_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 527.0
CMS2_k127_3061362_4 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 379.0
CMS2_k127_3061362_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
CMS2_k127_3061362_6 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 344.0
CMS2_k127_3061362_7 Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 297.0
CMS2_k127_3061362_8 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 286.0
CMS2_k127_3061362_9 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
CMS2_k127_3066234_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1131.0
CMS2_k127_3066234_1 Glycosyl transferase family 21 - - - 0.0 1079.0
CMS2_k127_3066234_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 578.0
CMS2_k127_3066234_11 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 564.0
CMS2_k127_3066234_12 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 556.0
CMS2_k127_3066234_13 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 563.0
CMS2_k127_3066234_14 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 546.0
CMS2_k127_3066234_15 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 530.0
CMS2_k127_3066234_16 Surface antigen variable number K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 504.0
CMS2_k127_3066234_17 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 483.0
CMS2_k127_3066234_18 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) K05844 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
CMS2_k127_3066234_19 PFAM Succinylglutamate desuccinylase Aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 446.0
CMS2_k127_3066234_2 Heat shock 70 kDa protein K04043 - - 0.0 1050.0
CMS2_k127_3066234_20 FeS assembly protein SufB K09014 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 434.0
CMS2_k127_3066234_21 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
CMS2_k127_3066234_22 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 398.0
CMS2_k127_3066234_23 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
CMS2_k127_3066234_24 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 376.0
CMS2_k127_3066234_25 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 358.0
CMS2_k127_3066234_26 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 353.0
CMS2_k127_3066234_27 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
CMS2_k127_3066234_28 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 317.0
CMS2_k127_3066234_29 FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 305.0
CMS2_k127_3066234_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.641e-303 936.0
CMS2_k127_3066234_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
CMS2_k127_3066234_31 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008746 280.0
CMS2_k127_3066234_32 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
CMS2_k127_3066234_33 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000002758 235.0
CMS2_k127_3066234_34 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000001875 224.0
CMS2_k127_3066234_35 PFAM MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000000000000002675 231.0
CMS2_k127_3066234_36 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000007789 224.0
CMS2_k127_3066234_37 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000002433 211.0
CMS2_k127_3066234_38 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000001098 198.0
CMS2_k127_3066234_39 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000001614 185.0
CMS2_k127_3066234_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.806e-253 789.0
CMS2_k127_3066234_40 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000001288 181.0
CMS2_k127_3066234_41 recombinase XerD - - - 0.00000000000000000000000000000000000000000008055 166.0
CMS2_k127_3066234_42 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000007271 156.0
CMS2_k127_3066234_43 Toprim domain - - - 0.00000000000000000000000000000000000001507 147.0
CMS2_k127_3066234_44 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000001142 145.0
CMS2_k127_3066234_45 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000004447 140.0
CMS2_k127_3066234_46 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.000000000000000000000000000000001816 148.0
CMS2_k127_3066234_47 response to oxidative stress K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000006109 133.0
CMS2_k127_3066234_48 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000001792 130.0
CMS2_k127_3066234_49 - - - - 0.000000000000000000000000000003963 123.0
CMS2_k127_3066234_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 3.012e-248 776.0
CMS2_k127_3066234_50 - - - - 0.0000000000000000000000000001005 123.0
CMS2_k127_3066234_51 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000000000000000003456 118.0
CMS2_k127_3066234_52 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000001261 104.0
CMS2_k127_3066234_53 protein acetylation - - - 0.0000000000000000000182 98.0
CMS2_k127_3066234_54 Domain of unknown function (DUF4845) - - - 0.000000000000000001569 91.0
CMS2_k127_3066234_55 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.000000000002794 70.0
CMS2_k127_3066234_56 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000002064 57.0
CMS2_k127_3066234_57 - K19168 - - 0.0006163 49.0
CMS2_k127_3066234_6 protease with the C-terminal PDZ domain - - - 2.991e-240 757.0
CMS2_k127_3066234_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.407e-226 707.0
CMS2_k127_3066234_8 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 8.912e-211 664.0
CMS2_k127_3066234_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 1.18e-204 682.0
CMS2_k127_3086373_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07641,K07711 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031667,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 477.0
CMS2_k127_3086373_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 398.0
CMS2_k127_3086373_2 Inner membrane protein involved in colicin E2 resistance K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 379.0
CMS2_k127_3086373_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002303 273.0
CMS2_k127_3086373_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
CMS2_k127_3086373_8 - - - - 0.0001125 48.0
CMS2_k127_3096761_0 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 427.0
CMS2_k127_3096761_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 366.0
CMS2_k127_3096761_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 279.0
CMS2_k127_3096761_3 PFAM SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000286 257.0
CMS2_k127_3096761_4 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001239 232.0
CMS2_k127_3096761_5 Domain of unknown function (DUF5062) - - - 0.000000000000000000000000000000000004041 138.0
CMS2_k127_3096761_6 PFAM SCP-like extracellular - - - 0.0000000000000000000000000000000001174 142.0
CMS2_k127_3096761_7 PFAM PspA IM30 - - - 0.0000000000000000000000000000000001399 143.0
CMS2_k127_3096761_8 - - - - 0.000000000000000000000000000004353 135.0
CMS2_k127_3096761_9 GGDEF domain K02282 - - 0.000000000000000000000000003097 119.0
CMS2_k127_3110168_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2055.0
CMS2_k127_3110168_1 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 4.338e-236 736.0
CMS2_k127_3110168_10 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 416.0
CMS2_k127_3110168_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 410.0
CMS2_k127_3110168_12 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 392.0
CMS2_k127_3110168_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 372.0
CMS2_k127_3110168_14 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 346.0
CMS2_k127_3110168_15 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
CMS2_k127_3110168_16 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 304.0
CMS2_k127_3110168_17 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 281.0
CMS2_k127_3110168_18 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 262.0
CMS2_k127_3110168_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000007134 230.0
CMS2_k127_3110168_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.063e-233 732.0
CMS2_k127_3110168_20 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000005587 222.0
CMS2_k127_3110168_21 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000004773 199.0
CMS2_k127_3110168_22 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000001437 195.0
CMS2_k127_3110168_23 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000001012 192.0
CMS2_k127_3110168_24 protein conserved in bacteria K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000001262 179.0
CMS2_k127_3110168_25 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000000007693 171.0
CMS2_k127_3110168_26 Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000000000000000000161 175.0
CMS2_k127_3110168_27 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000001666 175.0
CMS2_k127_3110168_28 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000005666 158.0
CMS2_k127_3110168_29 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000003147 163.0
CMS2_k127_3110168_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.805e-213 679.0
CMS2_k127_3110168_30 CDP-archaeol synthase K19664 - 2.7.7.67 0.00000000000000000000000000000000000003636 148.0
CMS2_k127_3110168_31 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000004428 145.0
CMS2_k127_3110168_32 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000003095 138.0
CMS2_k127_3110168_33 membrane protein domain - - - 0.00000000000000000000000000000001791 132.0
CMS2_k127_3110168_35 protein conserved in bacteria K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.0000000000000000000000004645 109.0
CMS2_k127_3110168_36 - - - - 0.0000000000000000000168 93.0
CMS2_k127_3110168_37 regulation of response to stimulus K02014,K13730 - - 0.000000000000001863 90.0
CMS2_k127_3110168_39 AAA domain K03112 - - 0.000000001862 68.0
CMS2_k127_3110168_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 586.0
CMS2_k127_3110168_40 - - - - 0.0000000479 60.0
CMS2_k127_3110168_41 Right handed beta helix region - - - 0.0000004077 63.0
CMS2_k127_3110168_42 cellulase activity K01209 - 3.2.1.55 0.000001237 61.0
CMS2_k127_3110168_43 COG NOG27188 non supervised orthologous group - - - 0.000008595 55.0
CMS2_k127_3110168_5 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 550.0
CMS2_k127_3110168_6 malate quinone oxidoreductase K00116 - 1.1.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 535.0
CMS2_k127_3110168_7 PFAM Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 521.0
CMS2_k127_3110168_8 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 503.0
CMS2_k127_3110168_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 460.0
CMS2_k127_3159970_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 4.174e-302 934.0
CMS2_k127_3159970_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.003e-234 730.0
CMS2_k127_3159970_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 447.0
CMS2_k127_3159970_3 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 416.0
CMS2_k127_3159970_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 311.0
CMS2_k127_3159970_5 - - - - 0.00000000000000000000000000000000004244 137.0
CMS2_k127_3159970_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.45 0.00000000007268 62.0
CMS2_k127_3159970_7 - - - - 0.000000005217 64.0
CMS2_k127_3159970_8 Domain of unknown function (DUF3362) - - - 0.00001774 47.0
CMS2_k127_3162816_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1080.0
CMS2_k127_3162816_1 pfam abc - - - 4.744e-283 877.0
CMS2_k127_3162816_10 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000002321 231.0
CMS2_k127_3162816_11 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000002084 205.0
CMS2_k127_3162816_12 Pilin (bacterial filament) K02650 - - 0.00000000000000000000000000000000000000000000000000479 185.0
CMS2_k127_3162816_13 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000503 157.0
CMS2_k127_3162816_14 Thiamine-binding protein - - - 0.0000000000000000000000000000000000009892 141.0
CMS2_k127_3162816_15 Sterol carrier protein - - - 0.00000000000000000000000000000000004004 138.0
CMS2_k127_3162816_16 - - - - 0.0000000000000000000000000000003534 126.0
CMS2_k127_3162816_17 - - - - 0.000000000000000000000000000003132 128.0
CMS2_k127_3162816_18 Domain of unknown function (DUF4156) - - - 0.000000000000000005086 87.0
CMS2_k127_3162816_19 Yip1 domain - - - 0.000000000000004506 84.0
CMS2_k127_3162816_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.41e-206 645.0
CMS2_k127_3162816_20 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.0000000000002428 80.0
CMS2_k127_3162816_21 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000007072 76.0
CMS2_k127_3162816_22 - - - - 0.0000000003022 63.0
CMS2_k127_3162816_23 Protein of unknown function (DUF3096) - - - 0.0000003243 53.0
CMS2_k127_3162816_24 COG1459 Type II secretory pathway, component PulF K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.000005905 58.0
CMS2_k127_3162816_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 521.0
CMS2_k127_3162816_4 Belongs to the Orn Lys Arg decarboxylase class-II family K01581,K01586 - 4.1.1.17,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 485.0
CMS2_k127_3162816_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03212 - 2.1.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 477.0
CMS2_k127_3162816_6 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 479.0
CMS2_k127_3162816_7 Predicted nucleotidyltransferase K07074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 345.0
CMS2_k127_3162816_8 PFAM regulatory protein AsnC Lrp family K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 258.0
CMS2_k127_3162816_9 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009393 254.0
CMS2_k127_3163077_0 Cytochrome c oxidase subunit K00376 - 1.7.2.4 5e-324 1000.0
CMS2_k127_3163077_1 Regulator of nitric oxide reductase transcription K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.112e-290 906.0
CMS2_k127_3163077_10 PFAM NosL family protein K19342 - - 0.0000000000000000000000000000000000000233 153.0
CMS2_k127_3163077_11 Domain of unknown function (DUF3817) - - - 0.00000000000000000000000000002665 119.0
CMS2_k127_3163077_12 - - - - 0.0000000000000000000000000008812 119.0
CMS2_k127_3163077_13 Protein of unknown function (DUF2621) - - - 0.0000009537 59.0
CMS2_k127_3163077_2 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 2.851e-246 803.0
CMS2_k127_3163077_3 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 593.0
CMS2_k127_3163077_4 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 551.0
CMS2_k127_3163077_5 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 371.0
CMS2_k127_3163077_6 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 367.0
CMS2_k127_3163077_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 330.0
CMS2_k127_3163077_8 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001041 267.0
CMS2_k127_3163077_9 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000000000000003291 167.0
CMS2_k127_3175288_0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 428.0
CMS2_k127_3175288_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 327.0
CMS2_k127_3175288_2 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000001501 174.0
CMS2_k127_3175288_3 PFAM Kelch - - - 0.0000000000000000000000000005005 133.0
CMS2_k127_3175288_4 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000002431 113.0
CMS2_k127_3175288_5 COG1943 Transposase and inactivated derivatives - - - 0.00000000000002799 73.0
CMS2_k127_3175288_6 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000008448 66.0
CMS2_k127_3175288_7 Transposase IS200 like K07491 - - 0.000000000009711 65.0
CMS2_k127_3175288_8 Galactose oxidase, central domain - - - 0.0000001204 66.0
CMS2_k127_3175288_9 cellulase activity - - - 0.00006809 57.0
CMS2_k127_3188052_0 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 425.0
CMS2_k127_3188052_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 372.0
CMS2_k127_3188052_2 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000000000000000008178 200.0
CMS2_k127_3188052_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000008715 65.0
CMS2_k127_3199003_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 2.17e-272 855.0
CMS2_k127_3199003_1 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 449.0
CMS2_k127_3199003_10 WHG domain - - - 0.000000000000000000000000000000000000000000006665 169.0
CMS2_k127_3199003_11 MazG-like family - - - 0.00000000000000000000000000000000000000000001596 165.0
CMS2_k127_3199003_12 membrane - - - 0.00000000000000000000000000000006919 128.0
CMS2_k127_3199003_13 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000005581 110.0
CMS2_k127_3199003_14 Desiccation protectant protein Lea14 homolog - GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009314,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009620,GO:0009628,GO:0009642,GO:0009644,GO:0016020,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0048046,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542 - 0.000001682 59.0
CMS2_k127_3199003_2 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 416.0
CMS2_k127_3199003_3 PFAM Major Facilitator Superfamily K08227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 410.0
CMS2_k127_3199003_4 PhnA domain K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 329.0
CMS2_k127_3199003_5 Penicillin-insensitive murein endopeptidase K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 308.0
CMS2_k127_3199003_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
CMS2_k127_3199003_7 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001482 257.0
CMS2_k127_3199003_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003962 244.0
CMS2_k127_3199003_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000001226 225.0
CMS2_k127_3213149_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.491e-198 629.0
CMS2_k127_3213149_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 588.0
CMS2_k127_3213149_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 514.0
CMS2_k127_3213149_3 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
CMS2_k127_3213149_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000006263 227.0
CMS2_k127_3213149_5 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000003379 207.0
CMS2_k127_3213149_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000003513 188.0
CMS2_k127_3213149_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000003313 175.0
CMS2_k127_3213149_8 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003961 103.0
CMS2_k127_3216412_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5e-323 1000.0
CMS2_k127_3216412_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.343e-317 994.0
CMS2_k127_3216412_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 312.0
CMS2_k127_3216412_11 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
CMS2_k127_3216412_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 281.0
CMS2_k127_3216412_13 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008161 268.0
CMS2_k127_3216412_14 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 262.0
CMS2_k127_3216412_15 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
CMS2_k127_3216412_16 CDP-alcohol phosphatidyltransferase K00995 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000005732 213.0
CMS2_k127_3216412_17 - - - - 0.000000000000000000000000000000000000000000000009987 182.0
CMS2_k127_3216412_18 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000009279 166.0
CMS2_k127_3216412_19 - - - - 0.000000000000000000000000000000000000000103 156.0
CMS2_k127_3216412_2 Hydrolase, alpha beta domain protein - - - 1.685e-258 809.0
CMS2_k127_3216412_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000001442 150.0
CMS2_k127_3216412_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000002474 151.0
CMS2_k127_3216412_22 Transcriptional regulator K13771 - - 0.000000000000000000000000000000000000008664 151.0
CMS2_k127_3216412_23 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000005219 138.0
CMS2_k127_3216412_24 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000000003363 135.0
CMS2_k127_3216412_25 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000009925 116.0
CMS2_k127_3216412_26 hemerythrin HHE cation binding domain - - - 0.0000000000000000000001107 104.0
CMS2_k127_3216412_28 photosynthesis K02656 - - 0.0000000000008714 73.0
CMS2_k127_3216412_29 - - - - 0.00000000001801 70.0
CMS2_k127_3216412_3 Domain of unknown function (DUF3482) - - - 1.541e-237 745.0
CMS2_k127_3216412_4 Participates in both transcription termination and antitermination K02600 - - 1.092e-222 700.0
CMS2_k127_3216412_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 392.0
CMS2_k127_3216412_6 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 395.0
CMS2_k127_3216412_7 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
CMS2_k127_3216412_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 362.0
CMS2_k127_3216412_9 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 318.0
CMS2_k127_3257582_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.035e-316 994.0
CMS2_k127_3257582_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.335e-291 902.0
CMS2_k127_3257582_10 Sulfatase - - - 1.689e-202 652.0
CMS2_k127_3257582_11 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 588.0
CMS2_k127_3257582_12 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
CMS2_k127_3257582_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 538.0
CMS2_k127_3257582_14 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 527.0
CMS2_k127_3257582_15 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 476.0
CMS2_k127_3257582_16 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 478.0
CMS2_k127_3257582_17 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 475.0
CMS2_k127_3257582_18 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 474.0
CMS2_k127_3257582_19 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 426.0
CMS2_k127_3257582_2 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 1.253e-271 843.0
CMS2_k127_3257582_20 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 404.0
CMS2_k127_3257582_21 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 351.0
CMS2_k127_3257582_22 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 338.0
CMS2_k127_3257582_23 Bacterial Ig-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 338.0
CMS2_k127_3257582_24 ADP-heptose LPS heptosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 317.0
CMS2_k127_3257582_25 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 304.0
CMS2_k127_3257582_26 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
CMS2_k127_3257582_27 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
CMS2_k127_3257582_28 Male sterility protein K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000003371 263.0
CMS2_k127_3257582_29 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
CMS2_k127_3257582_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.472e-244 759.0
CMS2_k127_3257582_30 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000004095 226.0
CMS2_k127_3257582_31 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000001405 213.0
CMS2_k127_3257582_32 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000002386 203.0
CMS2_k127_3257582_33 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
CMS2_k127_3257582_34 Acetyltransferase (GNAT) family K06718 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 0.000000000000000000000000000000000000000000000001239 179.0
CMS2_k127_3257582_35 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000006793 171.0
CMS2_k127_3257582_36 COG1846 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000001129 173.0
CMS2_k127_3257582_37 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000000000000004326 169.0
CMS2_k127_3257582_38 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000008858 163.0
CMS2_k127_3257582_39 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000004282 160.0
CMS2_k127_3257582_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.359e-240 762.0
CMS2_k127_3257582_40 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000003864 134.0
CMS2_k127_3257582_41 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000009122 126.0
CMS2_k127_3257582_42 MJ0042 family finger-like protein - - - 0.000000000000000000000000000000679 139.0
CMS2_k127_3257582_43 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.000000000000000000000002671 104.0
CMS2_k127_3257582_44 O-Antigen ligase K02847 - - 0.000000000000000000006155 106.0
CMS2_k127_3257582_45 protein conserved in bacteria - - - 0.0000000000000000003362 88.0
CMS2_k127_3257582_46 Peptidase S15 K06978 - - 0.000000001998 61.0
CMS2_k127_3257582_47 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.0009684 46.0
CMS2_k127_3257582_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 2.878e-221 692.0
CMS2_k127_3257582_6 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 3.059e-212 668.0
CMS2_k127_3257582_7 Belongs to the GARS family K01945 GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 3.63e-209 658.0
CMS2_k127_3257582_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 2.794e-208 657.0
CMS2_k127_3257582_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.041e-207 652.0
CMS2_k127_3343951_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.134e-321 992.0
CMS2_k127_3343951_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 375.0
CMS2_k127_3343951_2 COG1538 Outer membrane protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 379.0
CMS2_k127_3343951_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003797 289.0
CMS2_k127_3343951_4 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000006779 248.0
CMS2_k127_3343951_5 transcriptional regulator K16137 - - 0.000000000000000000000000000000000000000000005949 170.0
CMS2_k127_3343951_6 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000003554 124.0
CMS2_k127_3343951_7 protein conserved in bacteria - - - 0.0000000000000000000000000003727 118.0
CMS2_k127_3357102_0 HD domain - - - 0.0 1042.0
CMS2_k127_3357102_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 2.025e-241 752.0
CMS2_k127_3357102_10 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002852 260.0
CMS2_k127_3357102_11 DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
CMS2_k127_3357102_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000109 234.0
CMS2_k127_3357102_13 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000004406 235.0
CMS2_k127_3357102_14 low molecular weight phosphotyrosine protein phosphatase - - - 0.000000000000000000000000000000000000000000000000001774 185.0
CMS2_k127_3357102_15 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000000000000000000003199 181.0
CMS2_k127_3357102_16 Putative phosphatase (DUF442) - - - 0.0000000000000000000000000000006429 141.0
CMS2_k127_3357102_17 Transposase - - - 0.0000000000000000000000000002122 116.0
CMS2_k127_3357102_18 Transposase - - - 0.000000000001364 68.0
CMS2_k127_3357102_19 protein conserved in bacteria K09920 - - 0.000000000001469 74.0
CMS2_k127_3357102_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 1.665e-226 717.0
CMS2_k127_3357102_20 Transposase - - - 0.0000000005797 60.0
CMS2_k127_3357102_22 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000008698 55.0
CMS2_k127_3357102_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0017144,GO:0034641,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0044237,GO:0044248,GO:0044270,GO:0046209,GO:0046210,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748,GO:2001057 1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 614.0
CMS2_k127_3357102_4 Pyoverdine/dityrosine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 597.0
CMS2_k127_3357102_5 Bacterial periplasmic substrate-binding proteins K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 576.0
CMS2_k127_3357102_6 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 459.0
CMS2_k127_3357102_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 354.0
CMS2_k127_3357102_8 Pyoverdine/dityrosine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 335.0
CMS2_k127_3357102_9 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 293.0
CMS2_k127_3467216_0 Predicted membrane protein (DUF2339) - - - 2.651e-240 770.0
CMS2_k127_3467216_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 379.0
CMS2_k127_3467216_2 Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine. TcdA is also part of a sulfur transfer pathway K22132 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 331.0
CMS2_k127_3467216_3 Belongs to the pseudouridine synthase RsuA family K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002688 278.0
CMS2_k127_3467216_4 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 289.0
CMS2_k127_3489118_0 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.988e-226 705.0
CMS2_k127_3489118_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 488.0
CMS2_k127_3489118_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 276.0
CMS2_k127_3489118_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009012 273.0
CMS2_k127_3489118_12 TIGRFAM CRISPR-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000254 241.0
CMS2_k127_3489118_13 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000003383 246.0
CMS2_k127_3489118_14 pilus assembly protein, PilZ K02676 - - 0.0000000000000000000000000000000000000000000000000000173 190.0
CMS2_k127_3489118_15 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000006321 159.0
CMS2_k127_3489118_16 - - - - 0.00000000000000000000000000008034 123.0
CMS2_k127_3489118_18 Sulfite reductase K11181 - 1.8.99.5 0.0000000001006 62.0
CMS2_k127_3489118_19 - - - - 0.000009408 54.0
CMS2_k127_3489118_2 PFAM Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 471.0
CMS2_k127_3489118_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 424.0
CMS2_k127_3489118_4 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
CMS2_k127_3489118_5 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 343.0
CMS2_k127_3489118_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 336.0
CMS2_k127_3489118_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 334.0
CMS2_k127_3489118_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 321.0
CMS2_k127_3489118_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001211 289.0
CMS2_k127_3512029_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 8.685e-281 876.0
CMS2_k127_3512029_1 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 590.0
CMS2_k127_3512029_10 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 432.0
CMS2_k127_3512029_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 363.0
CMS2_k127_3512029_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 330.0
CMS2_k127_3512029_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 331.0
CMS2_k127_3512029_14 response regulator receiver K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
CMS2_k127_3512029_15 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 295.0
CMS2_k127_3512029_16 ErfK ybiS ycfS ynhG family protein K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002108 253.0
CMS2_k127_3512029_17 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001735 237.0
CMS2_k127_3512029_18 PFAM L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
CMS2_k127_3512029_19 phosphoribosyltransferase K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000008468 233.0
CMS2_k127_3512029_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 578.0
CMS2_k127_3512029_20 Cupin - - - 0.0000000000000000000000000000000000000000000009207 171.0
CMS2_k127_3512029_21 - - - - 0.00000000000000000000000000000002858 131.0
CMS2_k127_3512029_22 - - - - 0.00000000000000000000000000000006841 128.0
CMS2_k127_3512029_23 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000001783 117.0
CMS2_k127_3512029_24 Peptidoglycan-binding protein, CsiV - - - 0.0000000000000000000000009728 111.0
CMS2_k127_3512029_25 signal transduction histidine kinase K07678,K20974 - 2.7.13.3 0.000000000001177 72.0
CMS2_k127_3512029_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 544.0
CMS2_k127_3512029_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
CMS2_k127_3512029_5 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 526.0
CMS2_k127_3512029_6 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 502.0
CMS2_k127_3512029_7 COG0668 Small-conductance mechanosensitive channel K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 467.0
CMS2_k127_3512029_8 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 436.0
CMS2_k127_3512029_9 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 430.0
CMS2_k127_3513696_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.74e-278 865.0
CMS2_k127_3513696_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 6.099e-234 730.0
CMS2_k127_3513696_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002211 239.0
CMS2_k127_3513696_3 Phosphate-starvation-inducible E K13256 - - 0.00000000000000000000000000000000000005726 147.0
CMS2_k127_3513696_4 Rhodanese - - - 0.000000000000000000000000000000003044 132.0
CMS2_k127_3513696_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000007823 91.0
CMS2_k127_3513696_6 - - - - 0.000000000000000005795 84.0
CMS2_k127_3513696_7 - - - - 0.000005069 48.0
CMS2_k127_3513696_8 COG1943 Transposase and inactivated derivatives - - - 0.0003134 46.0
CMS2_k127_3581462_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.0 1168.0
CMS2_k127_3581462_1 Belongs to the AAA ATPase family K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 542.0
CMS2_k127_3581462_10 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000002982 203.0
CMS2_k127_3581462_11 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000002422 151.0
CMS2_k127_3581462_12 Lysin motif - - - 0.00000000000000000000000000000000008749 136.0
CMS2_k127_3581462_13 - - - - 0.000000000000000000000000000000001566 135.0
CMS2_k127_3581462_2 Exonuclease C-terminal K01141 - 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 538.0
CMS2_k127_3581462_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 499.0
CMS2_k127_3581462_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 412.0
CMS2_k127_3581462_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 369.0
CMS2_k127_3581462_6 Domain of Unknown Function (DUF350) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007171 282.0
CMS2_k127_3581462_7 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002589 269.0
CMS2_k127_3581462_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
CMS2_k127_3581462_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
CMS2_k127_3614402_0 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 565.0
CMS2_k127_3614402_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 405.0
CMS2_k127_3614402_2 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 399.0
CMS2_k127_3614402_3 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 342.0
CMS2_k127_3614402_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 301.0
CMS2_k127_3614402_6 ABC-type sugar transport system periplasmic component - - - 0.0000000000001283 85.0
CMS2_k127_3614402_7 Protein of unknown function (DUF2384) - - - 0.0000001711 58.0
CMS2_k127_3650840_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1704.0
CMS2_k127_3650840_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1010.0
CMS2_k127_3650840_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 484.0
CMS2_k127_3650840_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 368.0
CMS2_k127_3650840_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 353.0
CMS2_k127_3650840_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 316.0
CMS2_k127_3650840_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 287.0
CMS2_k127_3650840_15 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
CMS2_k127_3650840_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 274.0
CMS2_k127_3650840_17 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003302 246.0
CMS2_k127_3650840_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
CMS2_k127_3650840_19 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
CMS2_k127_3650840_2 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 2.999e-283 884.0
CMS2_k127_3650840_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001151 200.0
CMS2_k127_3650840_21 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000002237 192.0
CMS2_k127_3650840_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000001124 164.0
CMS2_k127_3650840_23 Protein of unknown function (DUF2818) - - - 0.0000000000000000000000000000002815 125.0
CMS2_k127_3650840_24 Preprotein translocase subunit SecG K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000001542 107.0
CMS2_k127_3650840_25 CRS1_YhbY K07574 - - 0.000000000000000000000003729 106.0
CMS2_k127_3650840_26 Domain of unknown function (DUF4149) - - - 0.00000000000000000000004613 107.0
CMS2_k127_3650840_27 - - - - 0.00000000199 63.0
CMS2_k127_3650840_28 Participates in both transcription termination and antitermination K02600 - - 0.0000000108 56.0
CMS2_k127_3650840_3 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 3.412e-263 832.0
CMS2_k127_3650840_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.598e-244 757.0
CMS2_k127_3650840_5 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 7.519e-239 747.0
CMS2_k127_3650840_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.269e-230 717.0
CMS2_k127_3650840_7 carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 1.093e-194 612.0
CMS2_k127_3650840_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 595.0
CMS2_k127_3650840_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 591.0
CMS2_k127_37891_0 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 1.792e-317 987.0
CMS2_k127_37891_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 520.0
CMS2_k127_37891_10 cold-shock protein K03704 - - 0.000000000000000000000000000000698 124.0
CMS2_k127_37891_11 MarR family - - - 0.0000000000000000000000000000252 122.0
CMS2_k127_37891_13 diguanylate cyclase - - - 0.000000000006079 70.0
CMS2_k127_37891_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 426.0
CMS2_k127_37891_3 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 398.0
CMS2_k127_37891_4 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 331.0
CMS2_k127_37891_5 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 292.0
CMS2_k127_37891_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001302 249.0
CMS2_k127_37891_7 OmpA-like transmembrane domain - - - 0.00000000000000000000000000000000000002687 153.0
CMS2_k127_37891_8 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000131 133.0
CMS2_k127_37891_9 cold-shock protein K03704 - - 0.00000000000000000000000000000001221 127.0
CMS2_k127_3947079_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.038e-194 617.0
CMS2_k127_3947079_1 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
CMS2_k127_3947079_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 306.0
CMS2_k127_3947079_3 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000199 158.0
CMS2_k127_3947079_4 Surface antigen - - - 0.000000000003181 70.0
CMS2_k127_398609_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 9.677e-216 675.0
CMS2_k127_398609_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 510.0
CMS2_k127_398609_2 4Fe-4S binding domain K00184,K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 432.0
CMS2_k127_398609_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 411.0
CMS2_k127_398609_4 Molybdopterin oxidoreductase Fe4S4 domain K08352,K08357,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 366.0
CMS2_k127_398609_5 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000009257 224.0
CMS2_k127_398609_6 - - - - 0.0000000000000000000000000000001798 130.0
CMS2_k127_398609_7 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000001919 111.0
CMS2_k127_398609_8 Protein of unknown function (DUF3617) - - - 0.0000005678 57.0
CMS2_k127_4089727_0 TonB-dependent copper receptor K02014 - - 2.58e-231 735.0
CMS2_k127_4089727_1 uracil-DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 300.0
CMS2_k127_4089727_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001642 239.0
CMS2_k127_4089727_3 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
CMS2_k127_4100226_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 9.132e-317 981.0
CMS2_k127_4100226_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 1.851e-284 878.0
CMS2_k127_4100226_2 STAS domain K03321 - - 8.092e-209 664.0
CMS2_k127_4100226_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 2.443e-201 635.0
CMS2_k127_4100226_4 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 398.0
CMS2_k127_4100226_5 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 366.0
CMS2_k127_4100226_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 290.0
CMS2_k127_4100226_7 Phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 290.0
CMS2_k127_4100226_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000005326 218.0
CMS2_k127_4100226_9 Chemoreceptor zinc-binding domain - - - 0.0000000000000001001 83.0
CMS2_k127_4103297_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1321.0
CMS2_k127_4103297_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1208.0
CMS2_k127_4103297_10 PFAM FAD linked oxidase domain protein K03777 - 1.1.5.12 2.123e-194 616.0
CMS2_k127_4103297_11 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 601.0
CMS2_k127_4103297_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 571.0
CMS2_k127_4103297_13 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 559.0
CMS2_k127_4103297_14 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 552.0
CMS2_k127_4103297_15 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 535.0
CMS2_k127_4103297_16 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 522.0
CMS2_k127_4103297_17 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 516.0
CMS2_k127_4103297_18 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 516.0
CMS2_k127_4103297_19 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 505.0
CMS2_k127_4103297_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 1.711e-219 685.0
CMS2_k127_4103297_20 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 491.0
CMS2_k127_4103297_21 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 493.0
CMS2_k127_4103297_22 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 451.0
CMS2_k127_4103297_23 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 444.0
CMS2_k127_4103297_24 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 474.0
CMS2_k127_4103297_25 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 440.0
CMS2_k127_4103297_26 Trypsin K04691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 436.0
CMS2_k127_4103297_27 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 424.0
CMS2_k127_4103297_28 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 420.0
CMS2_k127_4103297_29 PFAM LppC K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 422.0
CMS2_k127_4103297_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.775e-218 685.0
CMS2_k127_4103297_30 ABC transporter permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 395.0
CMS2_k127_4103297_31 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 401.0
CMS2_k127_4103297_32 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 391.0
CMS2_k127_4103297_33 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 386.0
CMS2_k127_4103297_34 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 385.0
CMS2_k127_4103297_35 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 386.0
CMS2_k127_4103297_36 COG0530 Ca2 Na antiporter K07301 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 382.0
CMS2_k127_4103297_37 ABC transporter ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 367.0
CMS2_k127_4103297_38 PFAM CBS domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
CMS2_k127_4103297_39 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
CMS2_k127_4103297_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 9.571e-215 672.0
CMS2_k127_4103297_40 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 350.0
CMS2_k127_4103297_41 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 334.0
CMS2_k127_4103297_42 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 337.0
CMS2_k127_4103297_43 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
CMS2_k127_4103297_44 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
CMS2_k127_4103297_45 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 312.0
CMS2_k127_4103297_46 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 311.0
CMS2_k127_4103297_47 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 309.0
CMS2_k127_4103297_48 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 306.0
CMS2_k127_4103297_49 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001015 281.0
CMS2_k127_4103297_5 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.26e-214 681.0
CMS2_k127_4103297_50 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
CMS2_k127_4103297_51 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002741 273.0
CMS2_k127_4103297_52 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000001743 262.0
CMS2_k127_4103297_53 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
CMS2_k127_4103297_54 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001654 258.0
CMS2_k127_4103297_55 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000001087 242.0
CMS2_k127_4103297_56 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000002466 231.0
CMS2_k127_4103297_57 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001597 218.0
CMS2_k127_4103297_58 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000004698 202.0
CMS2_k127_4103297_59 PFAM toluene tolerance K07323 - - 0.000000000000000000000000000000000000000000000000000004192 197.0
CMS2_k127_4103297_6 TIGRFAM ribonuclease, Rne Rng family K08301 - - 1.055e-208 659.0
CMS2_k127_4103297_60 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000002376 199.0
CMS2_k127_4103297_61 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000006342 190.0
CMS2_k127_4103297_62 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000004032 183.0
CMS2_k127_4103297_63 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000007533 188.0
CMS2_k127_4103297_64 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000001545 180.0
CMS2_k127_4103297_65 PFAM Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000002093 168.0
CMS2_k127_4103297_66 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000000000000005261 165.0
CMS2_k127_4103297_67 Belongs to the UPF0307 family K09889 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000001248 168.0
CMS2_k127_4103297_68 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000000000000005928 163.0
CMS2_k127_4103297_69 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000003258 152.0
CMS2_k127_4103297_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.15e-203 644.0
CMS2_k127_4103297_70 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000006264 139.0
CMS2_k127_4103297_71 - - - - 0.000000000000000000000000000000002336 134.0
CMS2_k127_4103297_72 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000002008 124.0
CMS2_k127_4103297_73 Phosphotransferase System K11189 - - 0.0000000000000000000000000004073 116.0
CMS2_k127_4103297_74 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000000001039 111.0
CMS2_k127_4103297_75 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000005155 106.0
CMS2_k127_4103297_76 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000001659 93.0
CMS2_k127_4103297_77 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000002456 95.0
CMS2_k127_4103297_78 - - - - 0.00000000000000000003906 91.0
CMS2_k127_4103297_79 NTP binding protein (Contains STAS domain) K07122 - - 0.0000000000000000003146 91.0
CMS2_k127_4103297_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.514e-203 642.0
CMS2_k127_4103297_81 Belongs to the BolA IbaG family - - - 0.000000000000001048 81.0
CMS2_k127_4103297_82 COG3170 Tfp pilus assembly protein FimV K07288,K08086 - - 0.00000000000007099 83.0
CMS2_k127_4103297_83 Protein of unknown function (DUF721) - - - 0.0000000000001963 76.0
CMS2_k127_4103297_84 Protein of unknown function DUF72 - - - 0.0000000000008959 76.0
CMS2_k127_4103297_85 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000396 74.0
CMS2_k127_4103297_86 Heavy-metal-associated domain K07213 - - 0.00000000001435 66.0
CMS2_k127_4103297_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 4.736e-202 635.0
CMS2_k127_414959_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 8.786e-216 674.0
CMS2_k127_414959_1 Diguanylate cyclase - - - 1.945e-194 640.0
CMS2_k127_414959_10 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001284 225.0
CMS2_k127_414959_11 PFAM NifZ K02597 - - 0.0000000000000000000000000000000000000000000000000000002505 201.0
CMS2_k127_414959_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000008571 164.0
CMS2_k127_414959_13 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000001372 138.0
CMS2_k127_414959_15 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000003355 123.0
CMS2_k127_414959_16 conserved protein - - - 0.000000000000000000000000003668 112.0
CMS2_k127_414959_17 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.00000000000000000000000001979 111.0
CMS2_k127_414959_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.187e-194 616.0
CMS2_k127_414959_3 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 507.0
CMS2_k127_414959_4 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 499.0
CMS2_k127_414959_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 475.0
CMS2_k127_414959_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 344.0
CMS2_k127_414959_7 iron-storage protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000008016 233.0
CMS2_k127_414959_8 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000002295 230.0
CMS2_k127_414959_9 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000007141 217.0
CMS2_k127_4163751_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1033.0
CMS2_k127_4163751_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 1.12e-282 888.0
CMS2_k127_4163751_10 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 436.0
CMS2_k127_4163751_11 sulfur carrier activity K04085,K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 418.0
CMS2_k127_4163751_12 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 376.0
CMS2_k127_4163751_13 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 378.0
CMS2_k127_4163751_14 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 389.0
CMS2_k127_4163751_15 TonB-dependent Receptor Plug K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 365.0
CMS2_k127_4163751_16 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 354.0
CMS2_k127_4163751_17 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
CMS2_k127_4163751_18 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
CMS2_k127_4163751_19 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 324.0
CMS2_k127_4163751_2 Sulfate permease and related transporters (MFS superfamily) K03321 - - 2.524e-246 768.0
CMS2_k127_4163751_20 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 313.0
CMS2_k127_4163751_21 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 313.0
CMS2_k127_4163751_22 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
CMS2_k127_4163751_23 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003068 247.0
CMS2_k127_4163751_24 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
CMS2_k127_4163751_25 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000003227 248.0
CMS2_k127_4163751_26 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000008211 239.0
CMS2_k127_4163751_27 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000001119 225.0
CMS2_k127_4163751_28 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000002626 214.0
CMS2_k127_4163751_29 COG1734 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000006947 125.0
CMS2_k127_4163751_3 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 596.0
CMS2_k127_4163751_31 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000005407 104.0
CMS2_k127_4163751_32 sulfur carrier activity K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000007201 95.0
CMS2_k127_4163751_33 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000749 80.0
CMS2_k127_4163751_34 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.0000439 46.0
CMS2_k127_4163751_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 604.0
CMS2_k127_4163751_5 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 578.0
CMS2_k127_4163751_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 542.0
CMS2_k127_4163751_7 Phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 483.0
CMS2_k127_4163751_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 471.0
CMS2_k127_4163751_9 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 457.0
CMS2_k127_4184299_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.25e-234 733.0
CMS2_k127_4184299_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.766e-216 681.0
CMS2_k127_4184299_10 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 324.0
CMS2_k127_4184299_11 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 323.0
CMS2_k127_4184299_12 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
CMS2_k127_4184299_13 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
CMS2_k127_4184299_14 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003263 250.0
CMS2_k127_4184299_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000477 241.0
CMS2_k127_4184299_16 Redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000002509 219.0
CMS2_k127_4184299_17 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
CMS2_k127_4184299_18 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000001561 208.0
CMS2_k127_4184299_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001412 195.0
CMS2_k127_4184299_2 drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
CMS2_k127_4184299_20 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002366 181.0
CMS2_k127_4184299_21 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000001705 184.0
CMS2_k127_4184299_22 Ferredoxin - - - 0.0000000000000000000000000000000000000000000003058 168.0
CMS2_k127_4184299_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000003331 131.0
CMS2_k127_4184299_24 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000002504 111.0
CMS2_k127_4184299_25 PD-(D/E)XK nuclease superfamily - - - 0.00000000001505 67.0
CMS2_k127_4184299_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 467.0
CMS2_k127_4184299_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 450.0
CMS2_k127_4184299_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 427.0
CMS2_k127_4184299_6 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 361.0
CMS2_k127_4184299_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 361.0
CMS2_k127_4184299_8 HAD-hyrolase-like K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 351.0
CMS2_k127_4184299_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
CMS2_k127_423805_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1084.0
CMS2_k127_423805_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 436.0
CMS2_k127_423805_10 Cytochrome C' - - - 0.0000000000001963 76.0
CMS2_k127_423805_11 ABC-2 type transporter K01992 - - 0.000000000002462 69.0
CMS2_k127_423805_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 423.0
CMS2_k127_423805_3 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 315.0
CMS2_k127_423805_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 297.0
CMS2_k127_423805_5 YsiA-like protein, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
CMS2_k127_423805_6 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000001205 190.0
CMS2_k127_423805_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000001436 197.0
CMS2_k127_423805_8 - - - - 0.0000000000000000000000000000000000001615 146.0
CMS2_k127_423805_9 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000009383 96.0
CMS2_k127_4294979_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.277e-302 932.0
CMS2_k127_4294979_1 Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 3.026e-285 880.0
CMS2_k127_4294979_10 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 414.0
CMS2_k127_4294979_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 409.0
CMS2_k127_4294979_12 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 381.0
CMS2_k127_4294979_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 383.0
CMS2_k127_4294979_14 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 362.0
CMS2_k127_4294979_15 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 362.0
CMS2_k127_4294979_16 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 344.0
CMS2_k127_4294979_17 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 344.0
CMS2_k127_4294979_18 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
CMS2_k127_4294979_19 molybdenum ABC transporter, periplasmic K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 297.0
CMS2_k127_4294979_2 Nitrogenase component 1 type Oxidoreductase K02587 - - 5.939e-255 793.0
CMS2_k127_4294979_20 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 291.0
CMS2_k127_4294979_21 Transcriptional regulator, ModE family K02019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
CMS2_k127_4294979_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009529 278.0
CMS2_k127_4294979_23 Dinitrogenase iron-molybdenum cofactor, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 260.0
CMS2_k127_4294979_24 Glutamine amido-transferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001407 255.0
CMS2_k127_4294979_25 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 244.0
CMS2_k127_4294979_26 Nitrogen fixation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 235.0
CMS2_k127_4294979_27 Putative heavy-metal chelation K09138 - - 0.00000000000000000000000000000000000000000000004976 182.0
CMS2_k127_4294979_28 PFAM Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000000006485 159.0
CMS2_k127_4294979_29 Ferredoxin - - - 0.0000000000000000000000000000000000000001005 154.0
CMS2_k127_4294979_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 613.0
CMS2_k127_4294979_30 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000008018 150.0
CMS2_k127_4294979_31 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000003198 145.0
CMS2_k127_4294979_32 NifT/FixU protein K02593 - - 0.000000000000000000000000000008165 119.0
CMS2_k127_4294979_33 - - - - 0.00000000000000000002215 93.0
CMS2_k127_4294979_34 4Fe-4S binding domain - - - 0.00000000000000000004769 92.0
CMS2_k127_4294979_35 Rop-like - - - 0.00000000000000000007515 91.0
CMS2_k127_4294979_37 COG0471 Di- and tricarboxylate transporters - - - 0.0000000003413 61.0
CMS2_k127_4294979_38 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.0000005841 57.0
CMS2_k127_4294979_39 Fe-S protein K06938 - - 0.000001345 58.0
CMS2_k127_4294979_4 Belongs to the NifD NifK NifE NifN family K02592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 600.0
CMS2_k127_4294979_40 oxygen carrier activity K07216 - - 0.00003664 51.0
CMS2_k127_4294979_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 572.0
CMS2_k127_4294979_6 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 527.0
CMS2_k127_4294979_7 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 519.0
CMS2_k127_4294979_8 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 512.0
CMS2_k127_4294979_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 441.0
CMS2_k127_4326393_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1230.0
CMS2_k127_4326393_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.418e-262 818.0
CMS2_k127_4326393_10 NnrU protein - - - 0.00000000000000000000000000000000000000000002885 167.0
CMS2_k127_4326393_11 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000001155 123.0
CMS2_k127_4326393_12 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000003061 117.0
CMS2_k127_4326393_13 cheY-homologous receiver domain - - - 0.000000000000000000000000007581 116.0
CMS2_k127_4326393_14 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000007969 106.0
CMS2_k127_4326393_15 Domain of unknown function (DUF4389) - - - 0.0000000000000000002211 94.0
CMS2_k127_4326393_16 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000158 73.0
CMS2_k127_4326393_17 37-kD nucleoid-associated bacterial protein K06899 - - 0.0000000006324 66.0
CMS2_k127_4326393_18 Protein of unknown function (DUF2384) - - - 0.00002238 53.0
CMS2_k127_4326393_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 9.677e-253 794.0
CMS2_k127_4326393_3 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 547.0
CMS2_k127_4326393_4 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 342.0
CMS2_k127_4326393_5 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
CMS2_k127_4326393_6 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
CMS2_k127_4326393_7 Disulfide bond formation protein DsbB - - - 0.000000000000000000000000000000000000000000000000000000001151 205.0
CMS2_k127_4326393_8 - - - - 0.00000000000000000000000000000000000000000000000000005076 198.0
CMS2_k127_4326393_9 protein conserved in bacteria K09912 - - 0.00000000000000000000000000000000000000000000002457 179.0
CMS2_k127_4339783_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 357.0
CMS2_k127_4339783_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 309.0
CMS2_k127_4339783_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000001124 174.0
CMS2_k127_4339783_3 Universal stress protein K06149 - - 0.00000000000000000000000000000000007425 138.0
CMS2_k127_4339783_4 - - - - 0.00000000001546 74.0
CMS2_k127_4339783_5 - - - - 0.00000000004918 65.0
CMS2_k127_4339783_7 - - - - 0.0000001234 56.0
CMS2_k127_4339783_8 - - - - 0.000003686 51.0
CMS2_k127_4339783_9 - - - - 0.00006045 46.0
CMS2_k127_4366907_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1136.0
CMS2_k127_4366907_1 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 4.17e-289 910.0
CMS2_k127_4366907_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000001146 201.0
CMS2_k127_4366907_11 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000002837 196.0
CMS2_k127_4366907_12 nuclease K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000002141 187.0
CMS2_k127_4366907_13 - - - - 0.000000000000000000000000000000000000000000000008766 181.0
CMS2_k127_4366907_14 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000009917 141.0
CMS2_k127_4366907_15 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000007938 124.0
CMS2_k127_4366907_16 ABC transporter substrate binding protein - - - 0.00000000000000000001417 102.0
CMS2_k127_4366907_17 - - - - 0.00000004911 59.0
CMS2_k127_4366907_19 - - - - 0.00003479 55.0
CMS2_k127_4366907_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.426e-232 724.0
CMS2_k127_4366907_20 Protein of unknown function (DUF3135) - - - 0.0001057 49.0
CMS2_k127_4366907_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 576.0
CMS2_k127_4366907_4 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 488.0
CMS2_k127_4366907_5 histidine kinase HAMP region domain protein K07678 GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 390.0
CMS2_k127_4366907_6 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 349.0
CMS2_k127_4366907_7 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 323.0
CMS2_k127_4366907_8 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 301.0
CMS2_k127_4366907_9 PFAM NUDIX hydrolase K08312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
CMS2_k127_4375866_0 Parallel beta-helix repeats - - - 0.0 1361.0
CMS2_k127_4375866_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 494.0
CMS2_k127_4375866_10 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000006236 193.0
CMS2_k127_4375866_11 - - - - 0.0000000000000000000000000000003538 128.0
CMS2_k127_4375866_12 Esterase PHB depolymerase K05973 - 3.1.1.75 0.0002592 53.0
CMS2_k127_4375866_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 471.0
CMS2_k127_4375866_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 470.0
CMS2_k127_4375866_4 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 373.0
CMS2_k127_4375866_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000115 262.0
CMS2_k127_4375866_6 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 266.0
CMS2_k127_4375866_7 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002416 279.0
CMS2_k127_4375866_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001035 245.0
CMS2_k127_4375866_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001204 236.0
CMS2_k127_4392940_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1335.0
CMS2_k127_4392940_1 FtsX-like permease family K02004 - - 5.043e-300 938.0
CMS2_k127_4392940_10 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001455 239.0
CMS2_k127_4392940_11 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000000002402 205.0
CMS2_k127_4392940_12 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000001007 170.0
CMS2_k127_4392940_2 AMP-binding enzyme C-terminal domain K00666 - - 3.035e-269 839.0
CMS2_k127_4392940_3 Beta-Casp domain K07576 - - 3.259e-203 643.0
CMS2_k127_4392940_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 601.0
CMS2_k127_4392940_5 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 404.0
CMS2_k127_4392940_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 367.0
CMS2_k127_4392940_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000346 255.0
CMS2_k127_4392940_8 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003629 261.0
CMS2_k127_4392940_9 modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000008204 255.0
CMS2_k127_4431974_0 protein conserved in bacteria K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.513e-211 671.0
CMS2_k127_4431974_1 Protein of unknown function (DUF1449) - - - 0.000000000000000000000000000000000000000000000000000002496 198.0
CMS2_k127_4431974_2 Stage II sporulation protein K06381 - - 0.0000000000000000000000000004885 122.0
CMS2_k127_4431974_3 COG1943 Transposase and inactivated derivatives - - - 0.000005069 52.0
CMS2_k127_4462961_0 Psort location Cytoplasmic, score 9.26 K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 566.0
CMS2_k127_4462961_1 Histidine kinase K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 563.0
CMS2_k127_4462961_2 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 368.0
CMS2_k127_4462961_3 Putative rRNA methylase - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
CMS2_k127_4466073_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1082.0
CMS2_k127_4466073_1 Protein of unknown function, DUF255 K06888 - - 5.79e-243 767.0
CMS2_k127_4466073_10 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 357.0
CMS2_k127_4466073_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 343.0
CMS2_k127_4466073_12 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 323.0
CMS2_k127_4466073_13 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 326.0
CMS2_k127_4466073_14 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
CMS2_k127_4466073_15 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
CMS2_k127_4466073_16 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 297.0
CMS2_k127_4466073_17 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001635 252.0
CMS2_k127_4466073_18 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
CMS2_k127_4466073_19 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18590 GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 0.00000000000000000000000000000000000000000000000000000009917 199.0
CMS2_k127_4466073_2 Part of a membrane complex involved in electron transport K03615 - - 1.174e-210 671.0
CMS2_k127_4466073_20 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000000000001746 162.0
CMS2_k127_4466073_21 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000007984 162.0
CMS2_k127_4466073_22 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000009347 169.0
CMS2_k127_4466073_23 Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000000000000000001334 146.0
CMS2_k127_4466073_24 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000009558 156.0
CMS2_k127_4466073_25 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000001506 136.0
CMS2_k127_4466073_26 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000008644 135.0
CMS2_k127_4466073_27 small protein containing a coiled-coil domain - - - 0.000000000000054 76.0
CMS2_k127_4466073_28 RibD C-terminal domain - - - 0.0000000004549 63.0
CMS2_k127_4466073_3 SAM-dependent K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 535.0
CMS2_k127_4466073_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 505.0
CMS2_k127_4466073_5 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 419.0
CMS2_k127_4466073_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 394.0
CMS2_k127_4466073_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 386.0
CMS2_k127_4466073_8 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 367.0
CMS2_k127_4466073_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
CMS2_k127_4467602_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.732e-278 865.0
CMS2_k127_4467602_1 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 620.0
CMS2_k127_4467602_10 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 247.0
CMS2_k127_4467602_11 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000000000000000000002512 232.0
CMS2_k127_4467602_12 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
CMS2_k127_4467602_13 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000105 205.0
CMS2_k127_4467602_14 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000002397 200.0
CMS2_k127_4467602_15 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000006009 203.0
CMS2_k127_4467602_16 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000008009 180.0
CMS2_k127_4467602_17 PFAM cytochrome c, class I - - - 0.0000000000000000000000002278 108.0
CMS2_k127_4467602_18 - - - - 0.0000000000003948 75.0
CMS2_k127_4467602_2 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 557.0
CMS2_k127_4467602_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 546.0
CMS2_k127_4467602_4 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
CMS2_k127_4467602_5 PFAM cation efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 302.0
CMS2_k127_4467602_6 Flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 298.0
CMS2_k127_4467602_7 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 294.0
CMS2_k127_4467602_8 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 297.0
CMS2_k127_4467602_9 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
CMS2_k127_4546840_0 DNA RNA helicase - - - 0.0 1178.0
CMS2_k127_4546840_1 Ferrous iron transport protein B K04759 - - 6.444e-250 787.0
CMS2_k127_4546840_10 (ABC) transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 302.0
CMS2_k127_4546840_11 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 301.0
CMS2_k127_4546840_12 Histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 310.0
CMS2_k127_4546840_13 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 292.0
CMS2_k127_4546840_14 Transcriptional regulatory protein, C terminal K07659 GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
CMS2_k127_4546840_15 Pseudouridine synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 276.0
CMS2_k127_4546840_16 protein domain (DUF2202) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003626 251.0
CMS2_k127_4546840_17 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
CMS2_k127_4546840_18 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
CMS2_k127_4546840_19 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
CMS2_k127_4546840_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.092e-247 788.0
CMS2_k127_4546840_20 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000003222 190.0
CMS2_k127_4546840_21 Crp-like helix-turn-helix domain K21563 - - 0.0000000000000000000000000000000000000000000000000001397 194.0
CMS2_k127_4546840_22 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000003145 192.0
CMS2_k127_4546840_23 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000002471 198.0
CMS2_k127_4546840_24 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000006826 185.0
CMS2_k127_4546840_25 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000000000000000000000000004666 168.0
CMS2_k127_4546840_26 redox protein regulator of disulfide bond formation K04063 - - 0.0000000000000000000000000000000000000000000009704 169.0
CMS2_k127_4546840_27 surface antigen - - - 0.000000000000000000000000000000000000000000002309 173.0
CMS2_k127_4546840_29 protein conserved in bacteria - - - 0.00000000000000000000000000000000000001927 148.0
CMS2_k127_4546840_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 580.0
CMS2_k127_4546840_30 Acetyltransferase (GNAT) domain K03830 - - 0.0000000000000000000000000000000000004817 145.0
CMS2_k127_4546840_31 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000000000001532 147.0
CMS2_k127_4546840_32 - - - - 0.00000000000000000000000000000000007565 140.0
CMS2_k127_4546840_33 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000000006061 138.0
CMS2_k127_4546840_34 Thioredoxin - - - 0.00000000000000000000000000006091 119.0
CMS2_k127_4546840_35 Rhodanese Homology Domain - - - 0.0000000000000000000000000009205 117.0
CMS2_k127_4546840_36 Belongs to the ompA family K03286 - - 0.0000000000000000006464 92.0
CMS2_k127_4546840_37 YfaZ precursor - - - 0.00000000000000000141 93.0
CMS2_k127_4546840_39 - - - - 0.000000000000007002 81.0
CMS2_k127_4546840_4 DbpA RNA binding domain K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 552.0
CMS2_k127_4546840_40 Protein of unknown function (DUF3012) - - - 0.00000000000004698 74.0
CMS2_k127_4546840_41 SH3 domain protein K07184 - - 0.000000001112 67.0
CMS2_k127_4546840_43 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.000000005576 63.0
CMS2_k127_4546840_44 PFAM Sporulation - - - 0.00000001574 64.0
CMS2_k127_4546840_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 448.0
CMS2_k127_4546840_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
CMS2_k127_4546840_7 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 311.0
CMS2_k127_4546840_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 324.0
CMS2_k127_4546840_9 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 310.0
CMS2_k127_4653038_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.178e-244 761.0
CMS2_k127_4653038_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 5.838e-244 761.0
CMS2_k127_4653038_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 494.0
CMS2_k127_4653038_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 471.0
CMS2_k127_4653038_12 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 471.0
CMS2_k127_4653038_13 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 471.0
CMS2_k127_4653038_14 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 462.0
CMS2_k127_4653038_15 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 451.0
CMS2_k127_4653038_16 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 436.0
CMS2_k127_4653038_17 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 404.0
CMS2_k127_4653038_18 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
CMS2_k127_4653038_19 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 353.0
CMS2_k127_4653038_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 1.114e-218 694.0
CMS2_k127_4653038_20 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 337.0
CMS2_k127_4653038_21 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 345.0
CMS2_k127_4653038_22 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 338.0
CMS2_k127_4653038_23 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 322.0
CMS2_k127_4653038_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 301.0
CMS2_k127_4653038_25 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 283.0
CMS2_k127_4653038_26 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 290.0
CMS2_k127_4653038_27 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
CMS2_k127_4653038_28 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000668 276.0
CMS2_k127_4653038_29 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 274.0
CMS2_k127_4653038_3 HD domain - - - 2.955e-197 629.0
CMS2_k127_4653038_30 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000004736 262.0
CMS2_k127_4653038_31 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 249.0
CMS2_k127_4653038_32 PFAM response regulator receiver K07183 - - 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
CMS2_k127_4653038_33 membrane - - - 0.00000000000000000000000000000000000000000000000000000000003526 210.0
CMS2_k127_4653038_34 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000000005613 178.0
CMS2_k127_4653038_35 nitric oxide dioxygenase activity K07140 - - 0.000000000000000000000000000000000000000000001335 168.0
CMS2_k127_4653038_36 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000002293 166.0
CMS2_k127_4653038_37 - - - - 0.000000000000000000000000000000000000004422 147.0
CMS2_k127_4653038_38 SMART Mov34 MPN PAD-1 family protein - - - 0.000000000000000000000000000000000000006768 151.0
CMS2_k127_4653038_39 - - - - 0.00000000000000000000000000000000002452 138.0
CMS2_k127_4653038_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 592.0
CMS2_k127_4653038_40 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000003236 138.0
CMS2_k127_4653038_41 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000001784 131.0
CMS2_k127_4653038_42 Belongs to the UPF0250 family - - - 0.00000000000000000000000003875 109.0
CMS2_k127_4653038_43 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000004616 96.0
CMS2_k127_4653038_44 - - - - 0.0000005189 53.0
CMS2_k127_4653038_5 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 575.0
CMS2_k127_4653038_6 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 569.0
CMS2_k127_4653038_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 544.0
CMS2_k127_4653038_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 537.0
CMS2_k127_4653038_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 537.0
CMS2_k127_4664233_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 419.0
CMS2_k127_4664233_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003046 276.0
CMS2_k127_4664233_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000008823 235.0
CMS2_k127_4664233_3 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000006877 193.0
CMS2_k127_4695186_0 Parallel beta-helix repeats - - - 0.0 1570.0
CMS2_k127_4695186_1 Histidine kinase - - - 2.615e-264 863.0
CMS2_k127_4695186_10 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 343.0
CMS2_k127_4695186_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 327.0
CMS2_k127_4695186_12 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 323.0
CMS2_k127_4695186_13 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
CMS2_k127_4695186_14 Uncharacterized conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000175 277.0
CMS2_k127_4695186_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005505 274.0
CMS2_k127_4695186_16 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007618 252.0
CMS2_k127_4695186_17 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000001008 205.0
CMS2_k127_4695186_18 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000867 185.0
CMS2_k127_4695186_19 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000001031 157.0
CMS2_k127_4695186_2 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 3.324e-202 647.0
CMS2_k127_4695186_20 fimbrial assembly K02461 - - 0.0000000000000000000000000001793 128.0
CMS2_k127_4695186_21 General secretion pathway protein H K02457 - - 0.00000000000000000000000001078 116.0
CMS2_k127_4695186_22 Pfam Response regulator receiver - - - 0.00000000000000000000009953 102.0
CMS2_k127_4695186_23 Pfam:N_methyl_2 K02459 - - 0.0000000000000000000001231 107.0
CMS2_k127_4695186_24 - - - - 0.0000000000000000000002948 102.0
CMS2_k127_4695186_25 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000000000006539 85.0
CMS2_k127_4695186_26 Type II secretion system protein B K02451 - - 0.000000002353 68.0
CMS2_k127_4695186_27 Prokaryotic N-terminal methylation motif K02458 - - 0.000000003467 63.0
CMS2_k127_4695186_28 COG0840 Methyl-accepting chemotaxis protein K02660 - - 0.000000003705 65.0
CMS2_k127_4695186_29 Putative metal-binding motif - - - 0.0000718 56.0
CMS2_k127_4695186_3 SMART Signal transduction response regulator, receiver region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 507.0
CMS2_k127_4695186_30 - K02463 - - 0.0002032 51.0
CMS2_k127_4695186_4 General secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 525.0
CMS2_k127_4695186_5 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 495.0
CMS2_k127_4695186_6 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 468.0
CMS2_k127_4695186_7 Type II secretory pathway component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 426.0
CMS2_k127_4695186_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 362.0
CMS2_k127_4695186_9 receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 336.0
CMS2_k127_4714333_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00171,K00172,K02573,K03737,K13795,K18930 - 1.2.7.1 0.0 1157.0
CMS2_k127_4714333_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1059.0
CMS2_k127_4714333_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.045e-199 628.0
CMS2_k127_4714333_11 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 589.0
CMS2_k127_4714333_12 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 588.0
CMS2_k127_4714333_13 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 561.0
CMS2_k127_4714333_14 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 527.0
CMS2_k127_4714333_15 Anthranilate synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 509.0
CMS2_k127_4714333_16 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 493.0
CMS2_k127_4714333_17 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 459.0
CMS2_k127_4714333_18 AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 473.0
CMS2_k127_4714333_19 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 457.0
CMS2_k127_4714333_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1053.0
CMS2_k127_4714333_20 Domains REC, sigma54 interaction, HTH8 K20919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 441.0
CMS2_k127_4714333_21 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006099,GO:0006101,GO:0006108,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009060,GO:0009061,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019898,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045333,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 425.0
CMS2_k127_4714333_22 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 412.0
CMS2_k127_4714333_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 351.0
CMS2_k127_4714333_24 2Fe-2S iron-sulfur cluster binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 344.0
CMS2_k127_4714333_25 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 335.0
CMS2_k127_4714333_26 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 327.0
CMS2_k127_4714333_27 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 319.0
CMS2_k127_4714333_28 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 292.0
CMS2_k127_4714333_29 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001617 258.0
CMS2_k127_4714333_3 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.729e-313 972.0
CMS2_k127_4714333_30 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000000000000000000000000996 248.0
CMS2_k127_4714333_31 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003438 246.0
CMS2_k127_4714333_32 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005694 229.0
CMS2_k127_4714333_33 Recombinase zinc beta ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009399 229.0
CMS2_k127_4714333_34 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000006391 202.0
CMS2_k127_4714333_35 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000003242 192.0
CMS2_k127_4714333_36 - - - - 0.00000000000000000000000000000000000000000004301 175.0
CMS2_k127_4714333_37 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000003241 160.0
CMS2_k127_4714333_38 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000003891 151.0
CMS2_k127_4714333_39 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000002329 142.0
CMS2_k127_4714333_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 2.212e-309 968.0
CMS2_k127_4714333_40 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001733 89.0
CMS2_k127_4714333_41 - - - - 0.000000000000000004285 93.0
CMS2_k127_4714333_43 - - - - 0.00000001309 63.0
CMS2_k127_4714333_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 3.471e-303 948.0
CMS2_k127_4714333_6 of the RND superfamily K07003 - - 6.875e-260 822.0
CMS2_k127_4714333_7 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 8.633e-258 803.0
CMS2_k127_4714333_8 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.257e-251 788.0
CMS2_k127_4714333_9 Part of a membrane complex involved in electron transport K03615 - - 6.466e-221 691.0
CMS2_k127_4723654_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0 1224.0
CMS2_k127_4723654_1 Ammonium Transporter Family K03320,K06580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 492.0
CMS2_k127_4723654_10 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000007214 121.0
CMS2_k127_4723654_11 - - - - 0.0000000000000000000000005491 108.0
CMS2_k127_4723654_2 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 342.0
CMS2_k127_4723654_3 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
CMS2_k127_4723654_4 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 295.0
CMS2_k127_4723654_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
CMS2_k127_4723654_6 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000002246 181.0
CMS2_k127_4723654_7 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000000000000000000756 173.0
CMS2_k127_4723654_8 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000001236 159.0
CMS2_k127_4723654_9 - - - - 0.0000000000000000000000000000000502 130.0
CMS2_k127_4778477_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1169.0
CMS2_k127_4778477_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 452.0
CMS2_k127_4778477_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000005139 202.0
CMS2_k127_4778477_3 Peptidyl-prolyl cis-trans K03774 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000009305 154.0
CMS2_k127_4807065_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 7.304e-298 986.0
CMS2_k127_4807065_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.865e-255 790.0
CMS2_k127_4807065_10 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 536.0
CMS2_k127_4807065_11 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 490.0
CMS2_k127_4807065_12 Belongs to the prokaryotic GSH synthase family K01920 GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 453.0
CMS2_k127_4807065_13 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 419.0
CMS2_k127_4807065_14 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 398.0
CMS2_k127_4807065_15 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 366.0
CMS2_k127_4807065_16 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 361.0
CMS2_k127_4807065_17 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 334.0
CMS2_k127_4807065_18 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
CMS2_k127_4807065_19 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
CMS2_k127_4807065_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.858e-204 641.0
CMS2_k127_4807065_20 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 284.0
CMS2_k127_4807065_21 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
CMS2_k127_4807065_22 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000001861 248.0
CMS2_k127_4807065_23 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000002458 231.0
CMS2_k127_4807065_24 tonb protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000001172 234.0
CMS2_k127_4807065_25 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
CMS2_k127_4807065_26 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000000000000000002552 220.0
CMS2_k127_4807065_27 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000003377 229.0
CMS2_k127_4807065_28 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000001273 182.0
CMS2_k127_4807065_29 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000007667 169.0
CMS2_k127_4807065_3 Dynamin family - - - 9.321e-201 644.0
CMS2_k127_4807065_30 nuclease - - - 0.000000000000000000000000000000000000000001289 167.0
CMS2_k127_4807065_31 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000000000000001454 159.0
CMS2_k127_4807065_32 COG2863 Cytochrome c553 - - - 0.0000000000000000000000000000000000000000167 161.0
CMS2_k127_4807065_33 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000002061 156.0
CMS2_k127_4807065_34 DUF167 K09131 - - 0.00000000000000000000000000000007239 126.0
CMS2_k127_4807065_35 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000001438 123.0
CMS2_k127_4807065_36 Domain of unknown function (DUF4426) - - - 0.000000000000000000000000001928 117.0
CMS2_k127_4807065_37 CheW domain protein K06598 - - 0.000000000000000167 86.0
CMS2_k127_4807065_38 - - - - 0.000000000000001142 80.0
CMS2_k127_4807065_4 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 613.0
CMS2_k127_4807065_5 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 579.0
CMS2_k127_4807065_6 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 595.0
CMS2_k127_4807065_7 PFAM Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 561.0
CMS2_k127_4807065_8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 547.0
CMS2_k127_4807065_9 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 548.0
CMS2_k127_4897302_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1383.0
CMS2_k127_4897302_1 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 8.277e-308 952.0
CMS2_k127_4897302_10 NosL K19342 - - 0.0000000000000000000000000000000000000000000000002136 184.0
CMS2_k127_4897302_11 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000002378 164.0
CMS2_k127_4897302_2 Regulator of nitric oxide reductase transcription K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.494e-252 798.0
CMS2_k127_4897302_3 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 460.0
CMS2_k127_4897302_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 423.0
CMS2_k127_4897302_5 peroxiredoxin glutaredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 384.0
CMS2_k127_4897302_6 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 342.0
CMS2_k127_4897302_7 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
CMS2_k127_4897302_8 Transcriptional regulator K04761 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 294.0
CMS2_k127_4897302_9 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
CMS2_k127_4945346_0 Peptidase_C39 like family - - - 1.741e-242 809.0
CMS2_k127_4945346_1 Sigma-54 interaction domain K11914 - - 1.151e-223 711.0
CMS2_k127_4945346_10 PFAM binding-protein-dependent transport systems inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 396.0
CMS2_k127_4945346_11 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
CMS2_k127_4945346_12 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
CMS2_k127_4945346_13 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008536 274.0
CMS2_k127_4945346_14 AsnC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
CMS2_k127_4945346_15 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000000000000000000000004149 204.0
CMS2_k127_4945346_16 Uncharacterized protein conserved in bacteria C-term(DUF2220) - - - 0.00000000000000000000000000008182 120.0
CMS2_k127_4945346_17 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 0.0007529 46.0
CMS2_k127_4945346_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.817e-208 657.0
CMS2_k127_4945346_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 594.0
CMS2_k127_4945346_4 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 554.0
CMS2_k127_4945346_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 523.0
CMS2_k127_4945346_6 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 484.0
CMS2_k127_4945346_7 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 476.0
CMS2_k127_4945346_8 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 426.0
CMS2_k127_4945346_9 Putrescine transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 420.0
CMS2_k127_5027402_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 527.0
CMS2_k127_5027402_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 451.0
CMS2_k127_5027402_10 TIGRFAM CRISPR-associated protein - - - 0.000000000000000000000000000000000000000000000002527 181.0
CMS2_k127_5027402_11 Ami_2 - - - 0.00000000000000000000000000002413 124.0
CMS2_k127_5027402_12 - - - - 0.00000000000000000000000001993 109.0
CMS2_k127_5027402_13 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000005095 81.0
CMS2_k127_5027402_2 radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 442.0
CMS2_k127_5027402_3 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 437.0
CMS2_k127_5027402_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 340.0
CMS2_k127_5027402_5 TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
CMS2_k127_5027402_6 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 321.0
CMS2_k127_5027402_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000003484 234.0
CMS2_k127_5027402_9 protein conserved in bacteria K09931 - - 0.0000000000000000000000000000000000000000000000000000002103 201.0
CMS2_k127_5038524_0 PFAM von Willebrand factor type A - - - 0.0 1114.0
CMS2_k127_5038524_1 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 3.449e-294 904.0
CMS2_k127_5038524_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000001769 157.0
CMS2_k127_5038524_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.755e-219 689.0
CMS2_k127_5038524_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.42e-218 683.0
CMS2_k127_5038524_4 COG0191 Fructose tagatose bisphosphate aldolase K01624 - 4.1.2.13 2.863e-204 638.0
CMS2_k127_5038524_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.489e-201 630.0
CMS2_k127_5038524_6 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 1.527e-201 633.0
CMS2_k127_5038524_7 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 471.0
CMS2_k127_5038524_8 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 404.0
CMS2_k127_5038524_9 PFAM methyltransferase small - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 312.0
CMS2_k127_5084276_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 3.451e-312 957.0
CMS2_k127_5084276_1 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 568.0
CMS2_k127_5084276_2 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 515.0
CMS2_k127_5084276_3 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 497.0
CMS2_k127_5084276_4 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000005977 220.0
CMS2_k127_5084276_5 - - - - 0.0000000000000000000000000000000000000000000004327 168.0
CMS2_k127_5109178_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.39e-265 832.0
CMS2_k127_5109178_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.943e-261 808.0
CMS2_k127_5109178_10 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 537.0
CMS2_k127_5109178_11 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 519.0
CMS2_k127_5109178_12 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 415.0
CMS2_k127_5109178_13 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 409.0
CMS2_k127_5109178_14 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
CMS2_k127_5109178_15 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 398.0
CMS2_k127_5109178_16 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 389.0
CMS2_k127_5109178_17 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 339.0
CMS2_k127_5109178_18 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 316.0
CMS2_k127_5109178_19 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 319.0
CMS2_k127_5109178_2 Large extracellular alpha-helical protein K06894 - - 8.679e-246 842.0
CMS2_k127_5109178_20 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 317.0
CMS2_k127_5109178_21 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 292.0
CMS2_k127_5109178_22 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009808 276.0
CMS2_k127_5109178_23 Transcriptional regulator, LysR K10918,K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001791 275.0
CMS2_k127_5109178_24 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000002997 237.0
CMS2_k127_5109178_25 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000003322 243.0
CMS2_k127_5109178_26 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005233 241.0
CMS2_k127_5109178_27 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007265 242.0
CMS2_k127_5109178_28 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000002508 238.0
CMS2_k127_5109178_29 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000009615 232.0
CMS2_k127_5109178_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 4.895e-233 730.0
CMS2_k127_5109178_30 Cytochrome B561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
CMS2_k127_5109178_31 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000006473 213.0
CMS2_k127_5109178_32 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000003048 217.0
CMS2_k127_5109178_33 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
CMS2_k127_5109178_34 pilus organization K07346 - - 0.0000000000000000000000000000000000000000000000000000000004087 211.0
CMS2_k127_5109178_35 regulatory protein, arsR - - - 0.000000000000000000000000000000000000000000001117 166.0
CMS2_k127_5109178_36 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000001088 164.0
CMS2_k127_5109178_38 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000005608 145.0
CMS2_k127_5109178_39 Thioredoxin-like - - - 0.0000000000000000000000000000008935 129.0
CMS2_k127_5109178_4 nitrogen regulation protein K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.897e-219 689.0
CMS2_k127_5109178_40 sulfur carrier activity K04085 - - 0.0000000000000000000000000006318 115.0
CMS2_k127_5109178_41 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000007706 122.0
CMS2_k127_5109178_44 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000001166 102.0
CMS2_k127_5109178_45 Spore Coat Protein U domain - - - 0.000000000000000000114 94.0
CMS2_k127_5109178_46 Domain of unknown function (DUF4124) - - - 0.00000000001127 72.0
CMS2_k127_5109178_47 COG2385 Sporulation protein and related proteins K06381 - - 0.00000003709 61.0
CMS2_k127_5109178_5 penicillin binding K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 601.0
CMS2_k127_5109178_6 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 563.0
CMS2_k127_5109178_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 558.0
CMS2_k127_5109178_8 glycyl-tRNA synthetase, alpha subunit K01878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 551.0
CMS2_k127_5109178_9 Belongs to the dihydroorotate dehydrogenase family K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 533.0
CMS2_k127_5118129_0 Alpha-2-Macroglobulin K06894 - - 0.0 1986.0
CMS2_k127_5118129_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1177.0
CMS2_k127_5118129_10 abc-type branched-chain amino acid transport K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 524.0
CMS2_k127_5118129_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 450.0
CMS2_k127_5118129_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 424.0
CMS2_k127_5118129_13 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 404.0
CMS2_k127_5118129_14 Histidine kinase K07637 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 401.0
CMS2_k127_5118129_15 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 307.0
CMS2_k127_5118129_16 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 291.0
CMS2_k127_5118129_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002637 280.0
CMS2_k127_5118129_18 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009672 274.0
CMS2_k127_5118129_19 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001338 264.0
CMS2_k127_5118129_2 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.249e-279 883.0
CMS2_k127_5118129_20 - K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000002044 250.0
CMS2_k127_5118129_21 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 253.0
CMS2_k127_5118129_22 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000004043 229.0
CMS2_k127_5118129_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000001971 203.0
CMS2_k127_5118129_24 Membrane K08988 - - 0.0000000000000000000000000000000000000000000000000000004646 200.0
CMS2_k127_5118129_25 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000004442 197.0
CMS2_k127_5118129_26 Outer Membrane Lipoprotein - - - 0.000000000000000000000000000000006809 135.0
CMS2_k127_5118129_27 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000846 117.0
CMS2_k127_5118129_28 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000001804 113.0
CMS2_k127_5118129_29 - - - - 0.000000000000000000002244 103.0
CMS2_k127_5118129_3 Diguanylate cyclase - - - 3.616e-270 865.0
CMS2_k127_5118129_30 - - - - 0.0000000000000000000114 100.0
CMS2_k127_5118129_31 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002155 74.0
CMS2_k127_5118129_32 - - - - 0.000000002986 61.0
CMS2_k127_5118129_4 SNF2 family N-terminal domain - - - 1.229e-222 720.0
CMS2_k127_5118129_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 7.852e-209 657.0
CMS2_k127_5118129_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 598.0
CMS2_k127_5118129_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 586.0
CMS2_k127_5118129_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 559.0
CMS2_k127_5118129_9 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 543.0
CMS2_k127_5141691_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1499.0
CMS2_k127_5141691_1 ABC transporter - - - 7.731e-301 928.0
CMS2_k127_5141691_2 - - - - 3.238e-224 700.0
CMS2_k127_5141691_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 304.0
CMS2_k127_5141691_4 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002449 250.0
CMS2_k127_5141691_5 PIN domain - - - 0.000000000000000000000000000000000000002156 149.0
CMS2_k127_5141691_6 copG family - - - 0.00000000000001422 78.0
CMS2_k127_5154801_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0 1178.0
CMS2_k127_5154801_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 6.724e-259 803.0
CMS2_k127_5154801_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 3.724e-198 626.0
CMS2_k127_5154801_3 NMT1-like family K15576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 608.0
CMS2_k127_5154801_4 PFAM binding-protein-dependent transport systems inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 448.0
CMS2_k127_5154801_5 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 430.0
CMS2_k127_5154801_6 Group 1 truncated hemoglobin K06886 - - 0.00000000000000000000000000000000000000000000002634 173.0
CMS2_k127_5154801_7 nitrite reductase K00363 - 1.7.1.15 0.00000000000000000000000000000000000000004475 154.0
CMS2_k127_5260210_0 Baseplate J-like protein - - - 5.372e-258 821.0
CMS2_k127_5260210_1 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 463.0
CMS2_k127_5260210_2 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
CMS2_k127_5260210_3 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000000000001171 175.0
CMS2_k127_5260210_4 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000004738 160.0
CMS2_k127_5260210_5 - - - - 0.00000000000000000000000000000000000006892 146.0
CMS2_k127_5260210_6 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.00000000000000000000598 107.0
CMS2_k127_5287826_0 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 1.914e-250 788.0
CMS2_k127_5287826_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 4.136e-227 711.0
CMS2_k127_5287826_2 COG1214 Inactive homolog of metal-dependent proteases K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001898 263.0
CMS2_k127_5287826_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000006992 213.0
CMS2_k127_5287826_4 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000007236 187.0
CMS2_k127_5287826_5 pathogenesis - - - 0.0000000000000000000000000006304 121.0
CMS2_k127_5287826_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000107 56.0
CMS2_k127_5320047_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - 0.0 1137.0
CMS2_k127_5320047_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 0.0 1034.0
CMS2_k127_5320047_10 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 371.0
CMS2_k127_5320047_11 of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
CMS2_k127_5320047_12 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 310.0
CMS2_k127_5320047_13 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001118 239.0
CMS2_k127_5320047_14 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000006081 244.0
CMS2_k127_5320047_15 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002137 231.0
CMS2_k127_5320047_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000005292 222.0
CMS2_k127_5320047_17 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000005554 175.0
CMS2_k127_5320047_19 PFAM thioesterase superfamily protein - - - 0.000000000007061 72.0
CMS2_k127_5320047_2 SMART Nucleotide binding protein, PINc K07175 - - 1.269e-226 710.0
CMS2_k127_5320047_21 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000001979 49.0
CMS2_k127_5320047_3 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 527.0
CMS2_k127_5320047_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 439.0
CMS2_k127_5320047_5 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 400.0
CMS2_k127_5320047_6 Peptidase family M48 K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 397.0
CMS2_k127_5320047_7 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 391.0
CMS2_k127_5320047_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 366.0
CMS2_k127_5320047_9 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 369.0
CMS2_k127_5321408_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1883.0
CMS2_k127_5321408_1 glutamate synthase - - - 4.404e-289 894.0
CMS2_k127_5321408_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000103 214.0
CMS2_k127_5321408_11 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000007818 175.0
CMS2_k127_5321408_12 Acyl-CoA hydrolase - - - 0.0000000000000000000000000000000000000000000003593 169.0
CMS2_k127_5321408_13 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000001164 78.0
CMS2_k127_5321408_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 7.913e-233 726.0
CMS2_k127_5321408_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 626.0
CMS2_k127_5321408_4 phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 396.0
CMS2_k127_5321408_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 366.0
CMS2_k127_5321408_6 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 318.0
CMS2_k127_5321408_7 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000003659 261.0
CMS2_k127_5321408_8 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
CMS2_k127_5321408_9 PFAM Glycosyl transferase, family 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001307 264.0
CMS2_k127_5359225_0 PFAM Glycosyl transferase family 2 - - - 2.015e-262 827.0
CMS2_k127_5359225_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 4.938e-207 655.0
CMS2_k127_5359225_10 - - - - 0.000000000000000000000000000000000000000000000000004321 186.0
CMS2_k127_5359225_11 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000798 170.0
CMS2_k127_5359225_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001018 136.0
CMS2_k127_5359225_13 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000005833 127.0
CMS2_k127_5359225_14 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000004787 118.0
CMS2_k127_5359225_15 AntiSigma factor - - - 0.000000000000000000003547 101.0
CMS2_k127_5359225_16 Membrane fusogenic activity K09806 - - 0.00000000000000000006548 91.0
CMS2_k127_5359225_17 - - - - 0.00000000007463 72.0
CMS2_k127_5359225_18 Cellulose synthase operon protein C C-terminus (BCSC_C) - - - 0.000000001002 72.0
CMS2_k127_5359225_2 Bacterial cellulose synthase subunit K20541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 429.0
CMS2_k127_5359225_20 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000001319 53.0
CMS2_k127_5359225_21 Acetyltransferase (GNAT) domain - - - 0.0000001544 53.0
CMS2_k127_5359225_3 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 343.0
CMS2_k127_5359225_4 Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 306.0
CMS2_k127_5359225_5 cellulose synthase operon protein YhjU - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009605 289.0
CMS2_k127_5359225_6 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000005739 227.0
CMS2_k127_5359225_7 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
CMS2_k127_5359225_8 - - - - 0.00000000000000000000000000000000000000000000000000001245 198.0
CMS2_k127_5359225_9 COG2346, Truncated hemoglobins K06886,K07006 - - 0.00000000000000000000000000000000000000000000000000006072 197.0
CMS2_k127_5369136_0 Multicopper oxidase - - - 3.207e-314 973.0
CMS2_k127_5369136_1 - - - - 1.004e-220 692.0
CMS2_k127_5369136_10 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008261 282.0
CMS2_k127_5369136_11 Protein of unknown function, DUF484 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003257 284.0
CMS2_k127_5369136_13 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
CMS2_k127_5369136_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
CMS2_k127_5369136_15 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000003002 220.0
CMS2_k127_5369136_16 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.000000000000000000000000000000000000000001591 161.0
CMS2_k127_5369136_18 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000002534 151.0
CMS2_k127_5369136_19 choline dehydrogenase activity - - - 0.0000000000000000000000000000000009077 135.0
CMS2_k127_5369136_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 445.0
CMS2_k127_5369136_21 - - - - 0.000000000000000000000000000001125 126.0
CMS2_k127_5369136_22 ketosteroid isomerase - - - 0.00000000000000000000000000001439 128.0
CMS2_k127_5369136_23 YebG protein K09918 - - 0.000000000000000000000000002801 113.0
CMS2_k127_5369136_24 Domain of unknown function (DUF1840) - - - 0.0000000000000000000000000965 109.0
CMS2_k127_5369136_25 - - - - 0.0000000000000000000000001083 113.0
CMS2_k127_5369136_26 Fe-S protein K06938 - - 0.00000000000000000000001596 102.0
CMS2_k127_5369136_28 Putative zinc- or iron-chelating domain - - - 0.000001302 55.0
CMS2_k127_5369136_29 transcriptional regulator PadR family protein - - - 0.0003959 49.0
CMS2_k127_5369136_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 451.0
CMS2_k127_5369136_4 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 443.0
CMS2_k127_5369136_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 390.0
CMS2_k127_5369136_6 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 394.0
CMS2_k127_5369136_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 347.0
CMS2_k127_5369136_8 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 341.0
CMS2_k127_5369136_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 326.0
CMS2_k127_5433789_0 Capsule polysaccharide biosynthesis protein K07266 - - 3.106e-220 703.0
CMS2_k127_5433789_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 574.0
CMS2_k127_5433789_10 PFAM Stf0 sulphotransferase - - - 0.00000000000000000000000000000000204 139.0
CMS2_k127_5433789_12 Sulfotransferase domain - - - 0.000000002228 68.0
CMS2_k127_5433789_13 EF hand - - - 0.0000002343 56.0
CMS2_k127_5433789_14 - - - - 0.0004865 51.0
CMS2_k127_5433789_2 Capsule polysaccharide biosynthesis protein K07265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 492.0
CMS2_k127_5433789_3 Galactosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 441.0
CMS2_k127_5433789_4 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 312.0
CMS2_k127_5433789_5 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 295.0
CMS2_k127_5433789_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 287.0
CMS2_k127_5433789_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001808 252.0
CMS2_k127_5433789_8 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000002056 204.0
CMS2_k127_5433789_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000002796 166.0
CMS2_k127_5468156_0 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 435.0
CMS2_k127_5468156_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 434.0
CMS2_k127_5468156_10 Helix-turn-helix domain - - - 0.00000000000000000000000002377 111.0
CMS2_k127_5468156_11 - - - - 0.00000000000000000005114 97.0
CMS2_k127_5468156_13 - - - - 0.0000000006271 65.0
CMS2_k127_5468156_14 - - - - 0.0000002493 54.0
CMS2_k127_5468156_15 Transcriptional regulator - - - 0.0000005352 53.0
CMS2_k127_5468156_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
CMS2_k127_5468156_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000109 249.0
CMS2_k127_5468156_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001559 248.0
CMS2_k127_5468156_5 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000327 233.0
CMS2_k127_5468156_6 peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000002441 218.0
CMS2_k127_5468156_7 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000008708 204.0
CMS2_k127_5468156_8 Peptidase M50B-like - - - 0.00000000000000000000000000000000000000002689 161.0
CMS2_k127_5468156_9 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000000000000000001684 146.0
CMS2_k127_5484096_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1244.0
CMS2_k127_5484096_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 9.821e-252 800.0
CMS2_k127_5484096_10 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
CMS2_k127_5484096_11 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 366.0
CMS2_k127_5484096_12 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
CMS2_k127_5484096_13 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 348.0
CMS2_k127_5484096_14 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 336.0
CMS2_k127_5484096_15 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 332.0
CMS2_k127_5484096_16 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
CMS2_k127_5484096_17 Pfam Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 299.0
CMS2_k127_5484096_18 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003307 249.0
CMS2_k127_5484096_19 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004745 264.0
CMS2_k127_5484096_2 inner membrane component K02011 - - 2.131e-250 782.0
CMS2_k127_5484096_20 SurA N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003518 245.0
CMS2_k127_5484096_21 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000135 248.0
CMS2_k127_5484096_22 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000003124 210.0
CMS2_k127_5484096_23 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000004399 222.0
CMS2_k127_5484096_24 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000513 204.0
CMS2_k127_5484096_25 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000001102 202.0
CMS2_k127_5484096_26 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000000000002006 183.0
CMS2_k127_5484096_27 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000001806 161.0
CMS2_k127_5484096_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000007769 151.0
CMS2_k127_5484096_29 - - - - 0.0000000000000000000000000000000006312 145.0
CMS2_k127_5484096_3 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.578e-209 660.0
CMS2_k127_5484096_30 Thioredoxin-like - - - 0.00000000000000000000000001275 116.0
CMS2_k127_5484096_31 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000003581 109.0
CMS2_k127_5484096_32 Protein of unknown function (DUF2782) - - - 0.000000000000000000001563 99.0
CMS2_k127_5484096_33 amine dehydrogenase activity - - - 0.0000000000000002623 90.0
CMS2_k127_5484096_34 - - - - 0.0000000000000004496 92.0
CMS2_k127_5484096_35 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000003052 73.0
CMS2_k127_5484096_36 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000006641 68.0
CMS2_k127_5484096_38 Protein of unknown function (DUF3501) - - - 0.0000003196 57.0
CMS2_k127_5484096_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 524.0
CMS2_k127_5484096_5 PFAM Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 493.0
CMS2_k127_5484096_6 PFAM Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 480.0
CMS2_k127_5484096_7 Ferric iron ABC transporter, ATP-binding protein K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 465.0
CMS2_k127_5484096_8 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 383.0
CMS2_k127_5484096_9 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
CMS2_k127_5490205_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1213.0
CMS2_k127_5490205_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.313e-291 903.0
CMS2_k127_5490205_10 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 425.0
CMS2_k127_5490205_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 372.0
CMS2_k127_5490205_12 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 355.0
CMS2_k127_5490205_13 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
CMS2_k127_5490205_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 323.0
CMS2_k127_5490205_15 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 317.0
CMS2_k127_5490205_16 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 316.0
CMS2_k127_5490205_17 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 300.0
CMS2_k127_5490205_18 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 288.0
CMS2_k127_5490205_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
CMS2_k127_5490205_2 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 3.545e-274 853.0
CMS2_k127_5490205_20 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
CMS2_k127_5490205_21 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000002132 225.0
CMS2_k127_5490205_22 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000001926 204.0
CMS2_k127_5490205_23 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000008649 195.0
CMS2_k127_5490205_24 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000004838 190.0
CMS2_k127_5490205_25 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000002152 186.0
CMS2_k127_5490205_26 - - - - 0.000000000000000000000002802 112.0
CMS2_k127_5490205_27 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000001694 90.0
CMS2_k127_5490205_28 - - - - 0.0000000000000002777 80.0
CMS2_k127_5490205_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.131e-240 750.0
CMS2_k127_5490205_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.128e-233 730.0
CMS2_k127_5490205_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 564.0
CMS2_k127_5490205_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 539.0
CMS2_k127_5490205_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 528.0
CMS2_k127_5490205_8 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 449.0
CMS2_k127_5490205_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 447.0
CMS2_k127_5696118_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.875e-240 749.0
CMS2_k127_5696118_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.995e-234 734.0
CMS2_k127_5696118_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 376.0
CMS2_k127_5696118_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 335.0
CMS2_k127_5696118_12 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000006399 216.0
CMS2_k127_5696118_13 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000001292 207.0
CMS2_k127_5696118_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000001941 196.0
CMS2_k127_5696118_15 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000001575 151.0
CMS2_k127_5696118_16 Belongs to the UPF0149 family K09895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000002607 153.0
CMS2_k127_5696118_17 cellulase activity - - - 0.0000000000000000000000003522 113.0
CMS2_k127_5696118_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000001099 101.0
CMS2_k127_5696118_19 - - - - 0.000000000000000000001111 95.0
CMS2_k127_5696118_2 FAD linked - - - 7.614e-229 714.0
CMS2_k127_5696118_20 TIGRFAM TIGR02449 family protein K09892 - - 0.000000000003026 70.0
CMS2_k127_5696118_3 Belongs to the GcvP family K00282 - 1.4.4.2 2.632e-205 647.0
CMS2_k127_5696118_4 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 1.277e-203 642.0
CMS2_k127_5696118_5 Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085) K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 507.0
CMS2_k127_5696118_6 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 472.0
CMS2_k127_5696118_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03184,K03185,K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 437.0
CMS2_k127_5696118_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 381.0
CMS2_k127_5696118_9 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 385.0
CMS2_k127_5771951_0 SMART Resolvase, RNase H domain protein fold K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.0 1052.0
CMS2_k127_5771951_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 1.002e-308 951.0
CMS2_k127_5771951_10 Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 426.0
CMS2_k127_5771951_11 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 403.0
CMS2_k127_5771951_12 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 373.0
CMS2_k127_5771951_13 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
CMS2_k127_5771951_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 370.0
CMS2_k127_5771951_15 Protein of unknown function (DUF2797) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
CMS2_k127_5771951_16 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
CMS2_k127_5771951_17 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 307.0
CMS2_k127_5771951_18 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001486 276.0
CMS2_k127_5771951_19 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000164 258.0
CMS2_k127_5771951_2 Belongs to the 5'-nucleotidase family K17224 - - 1.512e-304 942.0
CMS2_k127_5771951_20 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000002255 212.0
CMS2_k127_5771951_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000002696 215.0
CMS2_k127_5771951_22 Predicted integral membrane protein (DUF2269) - - - 0.00000000000000000000000000000000000000000000000000000000003233 210.0
CMS2_k127_5771951_23 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000000000000000000000000000363 203.0
CMS2_k127_5771951_25 Domain of unknown function (DUF4166) - - - 0.00000000000000000000000000000000000000000000005168 176.0
CMS2_k127_5771951_26 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000001627 177.0
CMS2_k127_5771951_27 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000002172 165.0
CMS2_k127_5771951_28 PFAM Pentapeptide - - - 0.000000000000000000000000000000000002188 147.0
CMS2_k127_5771951_29 oxidoreductase activity, acting on diphenols and related substances as donors K00411 - 1.10.2.2 0.00000000000000000000000000002756 124.0
CMS2_k127_5771951_3 Belongs to the peptidase S16 family - - - 3.072e-303 949.0
CMS2_k127_5771951_30 YcgL domain K09902 - - 0.000000000000000000000468 97.0
CMS2_k127_5771951_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 604.0
CMS2_k127_5771951_5 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 561.0
CMS2_k127_5771951_6 Synthesizes selenophosphate from selenide and ATP K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 518.0
CMS2_k127_5771951_7 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 517.0
CMS2_k127_5771951_8 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 477.0
CMS2_k127_5771951_9 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 445.0
CMS2_k127_5778085_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.239e-223 704.0
CMS2_k127_5778085_1 PFAM Type II secretion system protein E K02454 - - 6.363e-215 677.0
CMS2_k127_5778085_10 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000000000000000000000000000000000000000000000000002407 200.0
CMS2_k127_5778085_11 General secretion pathway protein C K02452 - - 0.0000000000000000000000000000000000000000000000000003538 196.0
CMS2_k127_5778085_12 General secretion pathway protein J K02459 - - 0.00000000000000000000000000000000000000000009673 168.0
CMS2_k127_5778085_13 type II secretion system protein N K02463 - - 0.00000000000000000000000000000000003164 145.0
CMS2_k127_5778085_14 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000000000000000000000000002357 119.0
CMS2_k127_5778085_15 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000005746 110.0
CMS2_k127_5778085_16 cell adhesion K02650,K02682 - - 0.0000000000000000000007793 97.0
CMS2_k127_5778085_17 general secretion pathway protein h K02457 - - 0.000000000000000001006 93.0
CMS2_k127_5778085_19 - K06950 - - 0.00000000003359 67.0
CMS2_k127_5778085_2 general secretion pathway protein D K02453 - - 1.085e-197 637.0
CMS2_k127_5778085_20 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.000001232 50.0
CMS2_k127_5778085_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 544.0
CMS2_k127_5778085_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 514.0
CMS2_k127_5778085_5 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 510.0
CMS2_k127_5778085_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 467.0
CMS2_k127_5778085_7 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 405.0
CMS2_k127_5778085_8 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006345 250.0
CMS2_k127_5778085_9 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000009271 223.0
CMS2_k127_5876512_1 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
CMS2_k127_5876512_2 ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000000000000000000000000003011 215.0
CMS2_k127_5876512_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000001374 194.0
CMS2_k127_5876512_5 - - - - 0.00000002493 65.0
CMS2_k127_6110211_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1184.0
CMS2_k127_6110211_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.821e-214 671.0
CMS2_k127_6110211_10 Cytochrome c - - - 0.000000000000000000000000000004233 123.0
CMS2_k127_6110211_11 Short C-terminal domain K08982 - - 0.0000000000000000000007301 96.0
CMS2_k127_6110211_12 Cytochrome c - - - 0.00000000000000000000376 96.0
CMS2_k127_6110211_2 Rhodanese Homology Domain - - - 9.741e-202 634.0
CMS2_k127_6110211_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 506.0
CMS2_k127_6110211_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 388.0
CMS2_k127_6110211_5 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 368.0
CMS2_k127_6110211_6 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 360.0
CMS2_k127_6110211_7 Alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 340.0
CMS2_k127_6110211_8 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
CMS2_k127_6110211_9 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000001857 208.0
CMS2_k127_6214444_0 Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
CMS2_k127_6214444_1 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
CMS2_k127_6214444_2 ATP synthase alpha/beta chain, C terminal domain K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008792 268.0
CMS2_k127_6214444_3 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000001099 125.0
CMS2_k127_621541_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.196e-320 995.0
CMS2_k127_621541_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.221e-238 752.0
CMS2_k127_621541_2 Belongs to the glycosyl hydrolase 57 family - - - 5.788e-223 705.0
CMS2_k127_621541_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.949e-206 649.0
CMS2_k127_621541_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.785e-198 623.0
CMS2_k127_621541_5 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 578.0
CMS2_k127_621541_6 Queuosine biosynthesis protein K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 466.0
CMS2_k127_621541_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 398.0
CMS2_k127_621541_8 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000009565 130.0
CMS2_k127_6226118_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.792e-275 859.0
CMS2_k127_6226118_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
CMS2_k127_6226118_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000002053 201.0
CMS2_k127_6226118_3 BON domain - - - 0.0000000000000000000000000000000000000000000000001182 185.0
CMS2_k127_6232533_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 5.908e-271 850.0
CMS2_k127_6232533_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 5.62e-246 778.0
CMS2_k127_6232533_10 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 443.0
CMS2_k127_6232533_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627,K09699 - 2.3.1.12,2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 438.0
CMS2_k127_6232533_12 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
CMS2_k127_6232533_13 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 335.0
CMS2_k127_6232533_14 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 288.0
CMS2_k127_6232533_15 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000002765 254.0
CMS2_k127_6232533_16 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009288 258.0
CMS2_k127_6232533_17 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001138 253.0
CMS2_k127_6232533_18 - - - - 0.00000000000000000000000000000000000000000000000002954 189.0
CMS2_k127_6232533_19 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000001225 181.0
CMS2_k127_6232533_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 600.0
CMS2_k127_6232533_20 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000008268 170.0
CMS2_k127_6232533_21 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000001411 163.0
CMS2_k127_6232533_22 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000001885 148.0
CMS2_k127_6232533_23 COG3245 Cytochrome c5 K02277 - 1.9.3.1 0.00000000000000000000000000000331 125.0
CMS2_k127_6232533_24 Cytochrome c - - - 0.0000000000000000000000000001599 132.0
CMS2_k127_6232533_25 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000002658 108.0
CMS2_k127_6232533_26 PFAM cytochrome c - - - 0.000000000000000004637 98.0
CMS2_k127_6232533_27 Pfam Transposase IS66 - - - 0.00000000000259 71.0
CMS2_k127_6232533_28 Metallo-beta-lactamase superfamily - - - 0.00000007674 53.0
CMS2_k127_6232533_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 583.0
CMS2_k127_6232533_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0019438,GO:0019464,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 537.0
CMS2_k127_6232533_5 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 499.0
CMS2_k127_6232533_6 PFAM ABC-type uncharacterised transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 482.0
CMS2_k127_6232533_7 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
CMS2_k127_6232533_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 465.0
CMS2_k127_6232533_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
CMS2_k127_6238390_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 399.0
CMS2_k127_6238390_1 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 328.0
CMS2_k127_6254339_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1105.0
CMS2_k127_6254339_1 Sodium:solute symporter family K14393 - - 2.193e-305 944.0
CMS2_k127_6254339_10 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 587.0
CMS2_k127_6254339_11 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 576.0
CMS2_k127_6254339_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 485.0
CMS2_k127_6254339_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 475.0
CMS2_k127_6254339_14 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 450.0
CMS2_k127_6254339_15 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 421.0
CMS2_k127_6254339_16 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 376.0
CMS2_k127_6254339_17 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 374.0
CMS2_k127_6254339_18 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 340.0
CMS2_k127_6254339_19 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 319.0
CMS2_k127_6254339_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 4.197e-289 893.0
CMS2_k127_6254339_20 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 315.0
CMS2_k127_6254339_21 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 291.0
CMS2_k127_6254339_22 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 299.0
CMS2_k127_6254339_23 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001252 275.0
CMS2_k127_6254339_24 Peptidase, M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 272.0
CMS2_k127_6254339_25 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
CMS2_k127_6254339_26 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003035 249.0
CMS2_k127_6254339_27 PFAM peptidylprolyl isomerase FKBP-type K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
CMS2_k127_6254339_28 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001369 228.0
CMS2_k127_6254339_29 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000002964 227.0
CMS2_k127_6254339_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 1.141e-281 877.0
CMS2_k127_6254339_30 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
CMS2_k127_6254339_31 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000003546 206.0
CMS2_k127_6254339_32 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000000008557 184.0
CMS2_k127_6254339_33 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.00000000000000000000000000000000000000000001197 168.0
CMS2_k127_6254339_34 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000008076 165.0
CMS2_k127_6254339_35 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000000000000000000000000000000292 168.0
CMS2_k127_6254339_36 Glycosyltransferase 36 associated - - - 0.00000000000000000000000000000000000000005569 158.0
CMS2_k127_6254339_37 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - 0.000000000000000000000000000000000000002029 154.0
CMS2_k127_6254339_38 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000001184 142.0
CMS2_k127_6254339_39 Rhodanese domain protein - - - 0.00000000000000000000000000000002829 128.0
CMS2_k127_6254339_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.088e-243 761.0
CMS2_k127_6254339_40 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000004711 117.0
CMS2_k127_6254339_41 Domain of unknown function (DUF4115) K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000008031 122.0
CMS2_k127_6254339_42 Sulfurtransferase - - - 0.00000000000000000000000729 102.0
CMS2_k127_6254339_43 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000003958 95.0
CMS2_k127_6254339_44 Protein of unknown function (DUF2905) - - - 0.000000000000000000008836 93.0
CMS2_k127_6254339_47 - - - - 0.00000126 54.0
CMS2_k127_6254339_5 Putative nucleotidyltransferase substrate binding domain K07182 - - 1.128e-239 756.0
CMS2_k127_6254339_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 1.702e-208 653.0
CMS2_k127_6254339_7 Diguanylate cyclase - - - 4.021e-203 670.0
CMS2_k127_6254339_8 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 7.362e-197 631.0
CMS2_k127_6254339_9 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.588e-195 620.0
CMS2_k127_6331068_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.483e-286 887.0
CMS2_k127_6331068_1 Cytochrome bd terminal oxidase subunit I K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 1.613e-269 837.0
CMS2_k127_6331068_10 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 510.0
CMS2_k127_6331068_11 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 420.0
CMS2_k127_6331068_12 oxidase, subunit K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 415.0
CMS2_k127_6331068_13 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 397.0
CMS2_k127_6331068_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
CMS2_k127_6331068_15 Protein of unknown function (DUF3549) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 297.0
CMS2_k127_6331068_16 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
CMS2_k127_6331068_17 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004308 240.0
CMS2_k127_6331068_18 Nitrite reductase heme biosynthesis H protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
CMS2_k127_6331068_19 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000001738 211.0
CMS2_k127_6331068_2 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 6.854e-261 809.0
CMS2_k127_6331068_20 heme biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000002235 208.0
CMS2_k127_6331068_21 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000408 168.0
CMS2_k127_6331068_22 SseB protein N-terminal domain - - - 0.000000000000000000000000000000000000000009226 157.0
CMS2_k127_6331068_23 - - - - 0.00000000000000000000000000000000003079 138.0
CMS2_k127_6331068_24 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.00000000000000000000000000005912 128.0
CMS2_k127_6331068_25 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000685 121.0
CMS2_k127_6331068_26 - - - - 0.0000000000000000000000000001759 120.0
CMS2_k127_6331068_27 RNA recognition motif K03655,K05592 - 3.6.4.12,3.6.4.13 0.0000000000000000000000508 104.0
CMS2_k127_6331068_28 GIY-YIG catalytic domain K07461 - - 0.0000000000000000002646 99.0
CMS2_k127_6331068_29 ERAD pathway - - - 0.000000000000000002031 91.0
CMS2_k127_6331068_3 Cytochrome D1 heme domain - - - 1.542e-225 710.0
CMS2_k127_6331068_30 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000000000000008132 77.0
CMS2_k127_6331068_4 membrane GTPase involved in stress response K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 2.717e-221 694.0
CMS2_k127_6331068_5 PFAM von Willebrand factor type A K02448 - - 3.437e-217 690.0
CMS2_k127_6331068_6 lysine 2,3-aminomutase K01843 - 5.4.3.2 2.113e-210 662.0
CMS2_k127_6331068_7 Belongs to the UPF0061 (SELO) family - - - 9.322e-208 656.0
CMS2_k127_6331068_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 601.0
CMS2_k127_6331068_9 cytochrome d1, heme region K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 562.0
CMS2_k127_6376198_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 608.0
CMS2_k127_6376198_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 532.0
CMS2_k127_6376198_2 endonuclease exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 448.0
CMS2_k127_6376198_3 pectinesterase activity K01728 - 4.2.2.2 0.00000000000000000000009084 111.0
CMS2_k127_6439163_0 Bacterial protein of unknown function (DUF853) K06915 - - 7.492e-220 691.0
CMS2_k127_6439163_1 Cytochrome c K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 525.0
CMS2_k127_6439163_2 PFAM Ion transport K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 342.0
CMS2_k127_6439163_3 Pas domain - - - 0.000000000000000002459 93.0
CMS2_k127_6439163_4 Belongs to the pseudouridine synthase RsuA family K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 0.000001216 50.0
CMS2_k127_6439163_5 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00001158 59.0
CMS2_k127_6462848_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1458.0
CMS2_k127_6462848_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.275e-316 982.0
CMS2_k127_6462848_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 543.0
CMS2_k127_6462848_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 380.0
CMS2_k127_6462848_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
CMS2_k127_6462848_5 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000002658 163.0
CMS2_k127_6462848_6 Glutaredoxin - - - 0.000000000000000000177 96.0
CMS2_k127_6462848_7 - - - - 0.000000000000000001002 86.0
CMS2_k127_6514405_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1076.0
CMS2_k127_6514405_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 357.0
CMS2_k127_6514405_2 dextransucrase activity K01728,K06324,K08100,K18197,K20276 GO:0005575,GO:0005576 1.16.3.3,1.3.3.5,4.2.2.2,4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
CMS2_k127_6514405_3 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000000001892 201.0
CMS2_k127_6514405_4 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000004129 128.0
CMS2_k127_6514405_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000002746 121.0
CMS2_k127_6846162_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 525.0
CMS2_k127_6846162_1 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 310.0
CMS2_k127_6846162_2 Metallo-beta-lactamase superfamily K04088,K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008623 279.0
CMS2_k127_6846162_3 - - - - 0.000000000000000003679 86.0
CMS2_k127_6851961_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 554.0
CMS2_k127_6851961_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 402.0
CMS2_k127_6851961_2 Secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 269.0
CMS2_k127_6851961_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
CMS2_k127_6851961_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
CMS2_k127_6851961_5 ABC-2 family transporter protein - - - 0.00000000000000000000000000002335 128.0
CMS2_k127_7037865_0 PFAM Glycoside hydrolase 15-related - - - 0.0 1149.0
CMS2_k127_7037865_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.625e-302 945.0
CMS2_k127_7037865_10 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 287.0
CMS2_k127_7037865_11 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000005868 236.0
CMS2_k127_7037865_12 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000001094 171.0
CMS2_k127_7037865_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000001055 168.0
CMS2_k127_7037865_14 Tetratricopeptide repeat - - - 0.000000000000000000000001985 120.0
CMS2_k127_7037865_15 Paraquat-inducible protein A - - - 0.0000000000000000000002508 104.0
CMS2_k127_7037865_16 - - - - 0.000000000000000000001767 95.0
CMS2_k127_7037865_17 PFAM Invasion gene expression up-regulator, SirB - - - 0.000000000005162 72.0
CMS2_k127_7037865_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 533.0
CMS2_k127_7037865_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 511.0
CMS2_k127_7037865_4 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 444.0
CMS2_k127_7037865_5 Na Pi-Cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 426.0
CMS2_k127_7037865_6 Glycosyltransferase like family 2 K21366 - 2.4.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 394.0
CMS2_k127_7037865_7 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 350.0
CMS2_k127_7037865_8 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 326.0
CMS2_k127_7037865_9 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 308.0
CMS2_k127_74995_0 e3 binding domain K00382 - 1.8.1.4 0.0 1292.0
CMS2_k127_74995_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05559,K14086 - - 0.0 1281.0
CMS2_k127_74995_10 Pfam:UPF0118 K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 410.0
CMS2_k127_74995_11 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 308.0
CMS2_k127_74995_12 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 288.0
CMS2_k127_74995_13 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
CMS2_k127_74995_14 antiporter K05562,K05569 - - 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
CMS2_k127_74995_15 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000608 217.0
CMS2_k127_74995_16 Thrombospondin type 3 repeat K03286 - - 0.0000000000000000000000000000000000000000000000000000000002343 212.0
CMS2_k127_74995_17 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000002925 190.0
CMS2_k127_74995_18 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000003023 178.0
CMS2_k127_74995_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560,K05567 - - 0.0000000000000000000000000000000000000000000001917 171.0
CMS2_k127_74995_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.33e-276 861.0
CMS2_k127_74995_20 cytochrome - - - 0.0000000000000000000000000000000000000000000006134 173.0
CMS2_k127_74995_21 Dihaem cytochrome c - - - 0.000000000000000000000000000000000000000000003853 169.0
CMS2_k127_74995_22 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000002686 153.0
CMS2_k127_74995_23 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05564,K05571 - - 0.000000000000000000000000000000000000008382 148.0
CMS2_k127_74995_24 Multisubunit Na H antiporter, MnhF subunit K05563 - - 0.00000000000000000000000000000000001573 138.0
CMS2_k127_74995_25 - - - - 0.000000000000000000000000001112 116.0
CMS2_k127_74995_26 Protein of unknown function (DUF3301) - - - 0.000000000000000001257 90.0
CMS2_k127_74995_27 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000001351 87.0
CMS2_k127_74995_28 bacterial OsmY and nodulation domain - - - 0.0000000007539 64.0
CMS2_k127_74995_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.773e-226 711.0
CMS2_k127_74995_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05561,K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 585.0
CMS2_k127_74995_5 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 556.0
CMS2_k127_74995_6 Dehydrogenase E1 component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 500.0
CMS2_k127_74995_7 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 492.0
CMS2_k127_74995_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 461.0
CMS2_k127_74995_9 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
CMS2_k127_75402_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1085.0
CMS2_k127_75402_1 - - - - 4.835e-209 655.0
CMS2_k127_75402_10 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000008232 215.0
CMS2_k127_75402_11 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000001498 211.0
CMS2_k127_75402_12 COG1186 Protein chain release factor B K15034 - - 0.0000000000000000000000000000000000000000000000000004394 187.0
CMS2_k127_75402_13 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000106 169.0
CMS2_k127_75402_14 - - - - 0.000000000000000000000000000000000000009272 150.0
CMS2_k127_75402_15 protein conserved in bacteria K09954 - - 0.0000000000000000000000000001319 127.0
CMS2_k127_75402_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000002303 114.0
CMS2_k127_75402_17 - - - - 0.000000000000000000000002156 107.0
CMS2_k127_75402_19 Protein of unknown function (DUF2384) - - - 0.000000007994 61.0
CMS2_k127_75402_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 8.929e-198 626.0
CMS2_k127_75402_3 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 476.0
CMS2_k127_75402_4 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 430.0
CMS2_k127_75402_5 Aldo keto - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 383.0
CMS2_k127_75402_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 383.0
CMS2_k127_75402_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 372.0
CMS2_k127_75402_8 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 350.0
CMS2_k127_75402_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
CMS2_k127_797600_0 (ABC) transporter K13926 - - 0.0 1056.0
CMS2_k127_797600_1 COG0845 Membrane-fusion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002797 282.0
CMS2_k127_797600_2 ABC-2 type transporter K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000001573 169.0
CMS2_k127_797600_3 COG1943 Transposase and inactivated derivatives - - - 0.000007511 51.0
CMS2_k127_82787_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 422.0
CMS2_k127_82787_1 VirC1 protein K03496 - - 0.000000000000000000000000000000000000000000000001847 181.0
CMS2_k127_82787_2 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000002691 152.0
CMS2_k127_82787_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000001634 127.0
CMS2_k127_82787_4 - K09858 - - 0.000000000000000000002239 97.0
CMS2_k127_82787_5 - - - - 0.000000101 54.0
CMS2_k127_82787_6 DsrE/DsrF-like family - - - 0.000001071 58.0
CMS2_k127_82787_7 - - - - 0.000001771 49.0
CMS2_k127_870572_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 2.206e-291 905.0
CMS2_k127_870572_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.055e-255 802.0
CMS2_k127_870572_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 474.0
CMS2_k127_870572_11 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 398.0
CMS2_k127_870572_12 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 376.0
CMS2_k127_870572_13 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 369.0
CMS2_k127_870572_14 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 370.0
CMS2_k127_870572_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 363.0
CMS2_k127_870572_16 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 343.0
CMS2_k127_870572_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
CMS2_k127_870572_18 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 293.0
CMS2_k127_870572_19 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 291.0
CMS2_k127_870572_2 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 2.545e-234 734.0
CMS2_k127_870572_20 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
CMS2_k127_870572_21 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
CMS2_k127_870572_22 subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
CMS2_k127_870572_23 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 262.0
CMS2_k127_870572_24 Inhibitor of apoptosis-promoting Bax1 K19416 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
CMS2_k127_870572_25 Maf-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005868 256.0
CMS2_k127_870572_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000167 237.0
CMS2_k127_870572_27 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
CMS2_k127_870572_28 low molecular weight K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000002899 212.0
CMS2_k127_870572_29 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000007239 190.0
CMS2_k127_870572_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.203e-234 761.0
CMS2_k127_870572_30 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000000000000000000000001751 168.0
CMS2_k127_870572_31 Protein of unknown function (DUF2953) - - - 0.00000000000000000000000000000000000000000006207 166.0
CMS2_k127_870572_32 COG0848 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000001368 154.0
CMS2_k127_870572_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001701 136.0
CMS2_k127_870572_34 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000006853 137.0
CMS2_k127_870572_35 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000006819 101.0
CMS2_k127_870572_36 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000001039 98.0
CMS2_k127_870572_37 Spore Coat - - - 0.00000000000000000001655 96.0
CMS2_k127_870572_39 domain, Protein - - - 0.0000001706 62.0
CMS2_k127_870572_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.176e-202 637.0
CMS2_k127_870572_40 Resolvase, N terminal domain - - - 0.0000002405 54.0
CMS2_k127_870572_41 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000007822 48.0
CMS2_k127_870572_42 Lipase (class 3) K01046 - 3.1.1.3 0.0003709 52.0
CMS2_k127_870572_43 - - - - 0.0004867 48.0
CMS2_k127_870572_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.212e-200 649.0
CMS2_k127_870572_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 1.97e-196 628.0
CMS2_k127_870572_7 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 585.0
CMS2_k127_870572_8 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 567.0
CMS2_k127_870572_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 511.0
CMS2_k127_92062_0 PFAM Glycoside hydrolase family 65, central catalytic - - - 0.0 1033.0
CMS2_k127_92062_1 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 6.653e-262 813.0
CMS2_k127_92062_10 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 327.0
CMS2_k127_92062_11 COGs COG1801 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 287.0
CMS2_k127_92062_12 ATP synthase B/B' CF(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000001909 240.0
CMS2_k127_92062_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000001406 233.0
CMS2_k127_92062_14 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000000000000415 212.0
CMS2_k127_92062_15 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000003379 207.0
CMS2_k127_92062_16 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000009659 209.0
CMS2_k127_92062_17 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000000000000000000000000001314 195.0
CMS2_k127_92062_18 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000201 171.0
CMS2_k127_92062_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000173 153.0
CMS2_k127_92062_2 DNA polymerase X family K02347 - - 7.604e-242 759.0
CMS2_k127_92062_20 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000000000005659 139.0
CMS2_k127_92062_21 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000221 129.0
CMS2_k127_92062_22 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000009637 130.0
CMS2_k127_92062_23 RNA-DNA hybrid ribonuclease activity K03469 - 3.1.26.4 0.00000000000000000000000000002173 126.0
CMS2_k127_92062_24 HNH endonuclease - - - 0.00000000000000000000000006425 109.0
CMS2_k127_92062_25 Dodecin K09165 - - 0.00000000000000000007366 93.0
CMS2_k127_92062_26 N-ATPase, AtpR subunit - - - 0.000006211 52.0
CMS2_k127_92062_3 ATP synthase alpha/beta chain, C terminal domain K02112 - 3.6.3.14 1.18e-196 615.0
CMS2_k127_92062_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 548.0
CMS2_k127_92062_5 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
CMS2_k127_92062_6 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 468.0
CMS2_k127_92062_7 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 444.0
CMS2_k127_92062_8 ATP synthase A chain K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 375.0
CMS2_k127_92062_9 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 341.0
CMS2_k127_95304_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 9.743e-246 772.0
CMS2_k127_95304_1 Ammonium transporter K03320 - - 1.643e-209 657.0
CMS2_k127_95304_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 413.0
CMS2_k127_95304_3 PFAM conserved K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 398.0
CMS2_k127_95304_4 pfam abc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005273 254.0
CMS2_k127_95304_5 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04752 - - 0.00000000000000000000000000000000000000000000000000000000004211 205.0
CMS2_k127_95304_6 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000007238 131.0
CMS2_k127_95304_7 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000001285 122.0
CMS2_k127_990130_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08356 - 1.20.2.1,1.20.9.1 0.0 1265.0
CMS2_k127_990130_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 544.0
CMS2_k127_990130_10 - - - - 0.0000000001013 64.0
CMS2_k127_990130_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000002794 224.0
CMS2_k127_990130_3 Rieske [2Fe-2S] domain K08355 - 1.20.2.1,1.20.9.1 0.00000000000000000000000000000000000000000000000000000000002877 209.0
CMS2_k127_990130_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000001537 190.0
CMS2_k127_990130_5 - - - - 0.00000000000000000000000000000000000000000000002629 174.0
CMS2_k127_990130_6 Putative thioesterase (yiiD_Cterm) - - - 0.0000000000000000000000000000000002799 136.0
CMS2_k127_990130_7 His Kinase A (phosphoacceptor) domain K07638 - 2.7.13.3 0.0000000000000000000000000000000004027 133.0
CMS2_k127_990130_8 Thioredoxin domain - - - 0.00000000000000000000000000000006026 131.0
CMS2_k127_990130_9 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000001448 103.0