Overview

ID MAG00776
Name DTH2_bin.41
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Planctomycetota
Class Phycisphaerae
Order Sedimentisphaerales
Family Anaerohalosphaeraceae
Genus UBA7708
Species
Assembly information
Completeness (%) 78.69
Contamination (%) 3.19
GC content (%) 49.0
N50 (bp) 6,939
Genome size (bp) 2,192,837

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1904

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10020972_0 leucine-rich repeat extensin-like protein K14709 - - 0.00000000000004493 79.0
DTH2_k127_10029041_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 4.319e-196 635.0
DTH2_k127_10029041_1 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 419.0
DTH2_k127_10029041_2 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 331.0
DTH2_k127_10029041_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 296.0
DTH2_k127_10029041_4 transcriptional regulator K13637 - - 0.0000000000000000000000001988 117.0
DTH2_k127_10029041_5 Belongs to the 'phage' integrase family - - - 0.00000001092 58.0
DTH2_k127_10029041_6 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000001769 61.0
DTH2_k127_10036361_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008461 268.0
DTH2_k127_10036361_1 Formate nitrite family of K21993 - - 0.00000000000000000000000000000000000000000000000000001804 200.0
DTH2_k127_10036361_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000001705 201.0
DTH2_k127_10036361_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000015 184.0
DTH2_k127_10036361_4 Ribonuclease B OB domain - - - 0.000000000000000000000000000001081 122.0
DTH2_k127_10054383_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 9.132e-235 739.0
DTH2_k127_10054383_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.334e-217 683.0
DTH2_k127_10054383_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002771 295.0
DTH2_k127_10054383_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000209 168.0
DTH2_k127_10054383_4 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.00000000000000000000000000000000001108 141.0
DTH2_k127_10054383_5 C subunit K02119 - - 0.000000000000000000000000000000003102 141.0
DTH2_k127_10054383_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000003503 106.0
DTH2_k127_10054383_7 PFAM Vacuolar H transporting two-sector ATPase F subunit K02122 - - 0.0004646 47.0
DTH2_k127_1046739_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 373.0
DTH2_k127_1046739_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
DTH2_k127_1075970_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 492.0
DTH2_k127_1075970_1 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 328.0
DTH2_k127_1075970_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000029 230.0
DTH2_k127_1075970_3 Carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000007559 194.0
DTH2_k127_1075970_4 TrkA-C domain K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000008005 185.0
DTH2_k127_107914_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 451.0
DTH2_k127_107914_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 367.0
DTH2_k127_107914_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000498 187.0
DTH2_k127_107914_3 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000004483 147.0
DTH2_k127_107914_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000007184 135.0
DTH2_k127_107914_5 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002605 120.0
DTH2_k127_107914_6 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000001937 85.0
DTH2_k127_107914_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000001168 76.0
DTH2_k127_1082943_0 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000004753 215.0
DTH2_k127_1087268_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.796e-315 987.0
DTH2_k127_1087268_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.092e-274 880.0
DTH2_k127_1087268_2 Domain of unknown function (DUF4954) - - - 2.875e-261 824.0
DTH2_k127_1087268_3 sugar isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 331.0
DTH2_k127_1087268_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002853 261.0
DTH2_k127_1103423_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1164.0
DTH2_k127_1103423_1 DeoR C terminal sensor domain - - - 0.0000000000000000000000000000000000006007 149.0
DTH2_k127_1103423_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000004773 83.0
DTH2_k127_1129159_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
DTH2_k127_1129159_1 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 316.0
DTH2_k127_1129159_2 PFAM Metal-dependent phosphohydrolase, HD K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 325.0
DTH2_k127_1129159_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
DTH2_k127_1129159_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000001598 250.0
DTH2_k127_1129159_5 COG1253 Hemolysins and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000491 256.0
DTH2_k127_1129159_6 - - - - 0.000000000000000000000000000000000000000000000000000004966 198.0
DTH2_k127_1129159_7 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000001782 131.0
DTH2_k127_1129159_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000006253 116.0
DTH2_k127_1129159_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000005562 78.0
DTH2_k127_1193980_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 7.301e-210 666.0
DTH2_k127_1193980_1 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 504.0
DTH2_k127_1193980_2 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 433.0
DTH2_k127_1193980_3 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 352.0
DTH2_k127_1193980_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000043 206.0
DTH2_k127_1193980_6 carbon utilization K02664 - - 0.000000000000000000003441 100.0
DTH2_k127_1193980_7 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000002863 65.0
DTH2_k127_1193980_8 type IV pilus modification protein PilV K02458,K02671,K02681 - - 0.000005096 55.0
DTH2_k127_1199448_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000005002 194.0
DTH2_k127_1227159_0 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000001409 180.0
DTH2_k127_1227159_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000003891 101.0
DTH2_k127_1234948_0 PFAM 2-nitropropane dioxygenase NPD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 374.0
DTH2_k127_1234948_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 371.0
DTH2_k127_1234948_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000305 188.0
DTH2_k127_1234948_3 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000002757 174.0
DTH2_k127_1234948_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00001073 53.0
DTH2_k127_1239795_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 555.0
DTH2_k127_1239795_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000004529 195.0
DTH2_k127_1239795_2 HEPN domain - - - 0.00000000000000000000000006106 112.0
DTH2_k127_1239795_3 nucleotidyltransferase activity K07076 - - 0.0008324 47.0
DTH2_k127_1246949_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 597.0
DTH2_k127_1246949_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 286.0
DTH2_k127_1246949_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 285.0
DTH2_k127_1246949_3 glycosyl transferase - - - 0.00000000000000009888 89.0
DTH2_k127_1267353_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 596.0
DTH2_k127_1267353_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000001836 135.0
DTH2_k127_1267353_2 alcohol dehydrogenase K12957,K13953 GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0008106,GO:0008150,GO:0008152,GO:0008270,GO:0016491,GO:0016614,GO:0016616,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.1 0.0000009448 51.0
DTH2_k127_1272479_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 511.0
DTH2_k127_1272479_1 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 496.0
DTH2_k127_1272479_2 Periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000001311 139.0
DTH2_k127_1272479_3 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000001467 124.0
DTH2_k127_127610_0 ABC-type multidrug transport system ATPase component K13926 - - 0.0 1475.0
DTH2_k127_127610_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1298.0
DTH2_k127_127610_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 589.0
DTH2_k127_127610_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 577.0
DTH2_k127_127610_4 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 407.0
DTH2_k127_127610_5 Glycosyl hydrolase family 38 C-terminal domain protein K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000002842 168.0
DTH2_k127_127610_6 Domain of unknown function (DUF4136) - - - 0.000000009352 64.0
DTH2_k127_1283690_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000001019 104.0
DTH2_k127_1283690_1 PEP-CTERM motif - - - 0.0008243 50.0
DTH2_k127_1290287_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 466.0
DTH2_k127_1290287_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000001081 147.0
DTH2_k127_1290287_2 efflux transmembrane transporter activity K12340 - - 0.000000001763 64.0
DTH2_k127_1295114_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 590.0
DTH2_k127_1295114_1 pyruvate kinase activity K00873,K00958 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 342.0
DTH2_k127_1295114_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 300.0
DTH2_k127_1295114_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000001243 62.0
DTH2_k127_1301652_0 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000001588 169.0
DTH2_k127_1301652_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000001774 141.0
DTH2_k127_1332173_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.507e-208 669.0
DTH2_k127_1332173_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 364.0
DTH2_k127_1332173_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000009291 128.0
DTH2_k127_1334698_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 371.0
DTH2_k127_1334698_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000002034 216.0
DTH2_k127_1334698_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000001362 181.0
DTH2_k127_1334698_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000004476 92.0
DTH2_k127_1334698_4 Sulfotransferase family - - - 0.0000000000000004531 87.0
DTH2_k127_1335829_0 Ig domain protein group 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 395.0
DTH2_k127_1335829_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000003159 192.0
DTH2_k127_1335829_2 Streptomycin adenylyltransferase - - - 0.000000000000000000002689 104.0
DTH2_k127_1335829_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000007425 68.0
DTH2_k127_137739_0 Belongs to the xylose isomerase family K01805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 597.0
DTH2_k127_137739_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
DTH2_k127_137739_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 273.0
DTH2_k127_137739_3 Xylose operon regulatory protein K02529 - - 0.000000000000000000000000000000000000000000000000000000000003819 222.0
DTH2_k127_137739_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000009828 178.0
DTH2_k127_137739_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000006624 136.0
DTH2_k127_137739_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000006799 146.0
DTH2_k127_137739_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000001879 126.0
DTH2_k127_1379154_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 1.796e-219 699.0
DTH2_k127_1379154_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 374.0
DTH2_k127_1379154_2 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 331.0
DTH2_k127_1379154_4 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000005135 164.0
DTH2_k127_1379154_5 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000162 149.0
DTH2_k127_142361_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 509.0
DTH2_k127_142361_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 468.0
DTH2_k127_142361_10 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004867 244.0
DTH2_k127_142361_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000002777 221.0
DTH2_k127_142361_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000001038 108.0
DTH2_k127_142361_13 - - - - 0.00000000000000000000004414 105.0
DTH2_k127_142361_14 - - - - 0.000000003279 61.0
DTH2_k127_142361_15 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000009053 58.0
DTH2_k127_142361_2 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 422.0
DTH2_k127_142361_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 359.0
DTH2_k127_142361_4 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 337.0
DTH2_k127_142361_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 327.0
DTH2_k127_142361_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 307.0
DTH2_k127_142361_7 PFAM response regulator receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 302.0
DTH2_k127_142361_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001627 277.0
DTH2_k127_142361_9 COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
DTH2_k127_1437952_0 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 558.0
DTH2_k127_1437952_1 Sigma-70, region 4 - - - 0.0000000000000000000000000000000005555 138.0
DTH2_k127_1437952_2 iron-sulfur cluster-binding protein K18979 - 1.17.99.6 0.0000000000003462 72.0
DTH2_k127_1442917_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 525.0
DTH2_k127_1442917_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 437.0
DTH2_k127_1442917_10 TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000003635 79.0
DTH2_k127_1442917_11 - - - - 0.000004239 55.0
DTH2_k127_1442917_2 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 354.0
DTH2_k127_1442917_3 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 292.0
DTH2_k127_1442917_4 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000007226 214.0
DTH2_k127_1442917_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000001112 184.0
DTH2_k127_1442917_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000003977 184.0
DTH2_k127_1442917_7 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000007392 167.0
DTH2_k127_1442917_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000001043 158.0
DTH2_k127_1442917_9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000003644 89.0
DTH2_k127_1443967_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 544.0
DTH2_k127_1443967_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
DTH2_k127_1443967_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000428 218.0
DTH2_k127_1478559_0 Acetyl esterase K01060 - 3.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 490.0
DTH2_k127_1478559_1 PFAM HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005093 291.0
DTH2_k127_1478559_2 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000005022 244.0
DTH2_k127_1478559_3 thioesterase K07107 - - 0.000000000000000000000000000002429 126.0
DTH2_k127_1478559_4 - - - - 0.000000002655 60.0
DTH2_k127_1478559_5 Zinc carboxypeptidase - - - 0.00000695 52.0
DTH2_k127_1494573_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 415.0
DTH2_k127_1494573_1 Glycogen debranching enzyme K03931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 406.0
DTH2_k127_1494573_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000007735 269.0
DTH2_k127_1494573_3 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000008002 93.0
DTH2_k127_1511793_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 424.0
DTH2_k127_1511793_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 267.0
DTH2_k127_1511793_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007825 248.0
DTH2_k127_1511793_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000001825 167.0
DTH2_k127_1511793_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000648 151.0
DTH2_k127_1511793_5 transcriptional regulator, AsnC family - - - 0.0000000000000000000000000000000000004263 146.0
DTH2_k127_1511793_6 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.0000000000003311 79.0
DTH2_k127_1511793_7 PFAM cytochrome c assembly protein - - - 0.0000003334 61.0
DTH2_k127_1511793_8 - - - - 0.0003791 49.0
DTH2_k127_1526683_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.846e-222 700.0
DTH2_k127_1526683_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 620.0
DTH2_k127_1526683_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 295.0
DTH2_k127_1526683_3 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009389 246.0
DTH2_k127_1526683_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000001513 190.0
DTH2_k127_1526683_5 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000004939 170.0
DTH2_k127_1526683_6 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000002013 98.0
DTH2_k127_1526683_7 Nucleotidyltransferase domain - - - 0.00000000000000002124 85.0
DTH2_k127_1526683_8 HEPN domain - - - 0.00000000000003396 79.0
DTH2_k127_1526683_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000005378 68.0
DTH2_k127_1534317_0 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000002885 213.0
DTH2_k127_1534317_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000001835 189.0
DTH2_k127_1542421_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 443.0
DTH2_k127_1542421_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 443.0
DTH2_k127_1542421_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
DTH2_k127_1542421_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001456 281.0
DTH2_k127_1542421_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000002737 177.0
DTH2_k127_1542421_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000018 129.0
DTH2_k127_1542421_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000004086 69.0
DTH2_k127_1542421_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000001245 58.0
DTH2_k127_1599538_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 428.0
DTH2_k127_1599538_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000004036 239.0
DTH2_k127_1599538_2 COG0859 ADP-heptose LPS heptosyltransferase K02843 - - 0.0000000000000000000000000000000000000000000000000000000000176 218.0
DTH2_k127_1599538_3 D,D-heptose 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000000000002861 177.0
DTH2_k127_1599538_4 Glycosyltransferase Family 4 K02844 - - 0.000000000002692 75.0
DTH2_k127_1603139_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 454.0
DTH2_k127_1603139_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 370.0
DTH2_k127_1603139_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000001622 270.0
DTH2_k127_1603139_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000002334 136.0
DTH2_k127_1603139_4 PFAM DNA polymerase, beta domain protein region K07075 - - 0.0000000000000000007782 89.0
DTH2_k127_1631217_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1355.0
DTH2_k127_1631217_1 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 622.0
DTH2_k127_1631217_10 Permease, YjgP YjgQ family K11720 - - 0.0000004548 59.0
DTH2_k127_1631217_11 Lysin motif - - - 0.00000122 61.0
DTH2_k127_1631217_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 462.0
DTH2_k127_1631217_3 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 349.0
DTH2_k127_1631217_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
DTH2_k127_1631217_5 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000678 250.0
DTH2_k127_1631217_6 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000005072 95.0
DTH2_k127_1631217_7 YHS domain - - - 0.00000000000006116 76.0
DTH2_k127_1631217_8 Permease YjgP YjgQ family K07091 - - 0.000000000000281 83.0
DTH2_k127_1631217_9 YHS domain - - - 0.0000000000009245 81.0
DTH2_k127_1650560_0 beta-galactosidase activity - - - 6.309e-209 670.0
DTH2_k127_1650560_1 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 392.0
DTH2_k127_1650560_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
DTH2_k127_1650560_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000139 218.0
DTH2_k127_1650560_4 Transposase K03589,K07491 - - 0.000000000000000000000000000000000000000000000000000000003671 208.0
DTH2_k127_1650560_5 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000005491 165.0
DTH2_k127_1657170_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000001704 248.0
DTH2_k127_1657170_1 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000003324 132.0
DTH2_k127_1669474_0 Domain of unknown function (DUF2088) - - - 2.052e-194 612.0
DTH2_k127_1669474_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 415.0
DTH2_k127_1712133_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 1.348e-299 951.0
DTH2_k127_1721796_0 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 439.0
DTH2_k127_1721796_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000001986 233.0
DTH2_k127_1721796_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000005791 99.0
DTH2_k127_1744635_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.101e-207 655.0
DTH2_k127_1744635_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 372.0
DTH2_k127_1744635_2 Belongs to the alpha-IPM synthase homocitrate synthase family - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 357.0
DTH2_k127_1744635_3 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 306.0
DTH2_k127_1744635_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000004224 202.0
DTH2_k127_1744635_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000001372 203.0
DTH2_k127_1744635_6 histidine kinase A domain protein - - - 0.0000000000000000000000000000000001199 151.0
DTH2_k127_1744635_7 helix_turn_helix, Lux Regulon - - - 0.00000004121 66.0
DTH2_k127_1744635_9 Response regulator receiver K03413 - - 0.0004608 48.0
DTH2_k127_178210_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.357e-223 707.0
DTH2_k127_178210_1 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000002725 261.0
DTH2_k127_178210_2 Iron (Metal) dependent repressor, DtxR family K03709 - - 0.000000000000000000000000000000000007869 141.0
DTH2_k127_178210_3 FeoA K04758 - - 0.0000000001064 64.0
DTH2_k127_1792508_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 3.834e-299 955.0
DTH2_k127_1792508_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.658e-209 669.0
DTH2_k127_1792508_2 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004171 306.0
DTH2_k127_1792508_3 Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
DTH2_k127_1792508_4 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000623 215.0
DTH2_k127_1792508_5 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000001641 157.0
DTH2_k127_1792508_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000004065 143.0
DTH2_k127_1793101_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
DTH2_k127_1793101_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002384 277.0
DTH2_k127_1793101_2 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000003598 216.0
DTH2_k127_1793101_3 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000009012 153.0
DTH2_k127_1793101_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000001413 113.0
DTH2_k127_1793101_5 23S rRNA-intervening sequence protein - - - 0.00000000000000000000001388 105.0
DTH2_k127_179397_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 323.0
DTH2_k127_179397_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 287.0
DTH2_k127_179397_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000001001 246.0
DTH2_k127_179397_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000002701 221.0
DTH2_k127_179397_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000003017 88.0
DTH2_k127_179397_5 General secretion pathway protein K02456 - - 0.000003242 53.0
DTH2_k127_1821790_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
DTH2_k127_1821790_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 293.0
DTH2_k127_1821790_2 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000001216 166.0
DTH2_k127_185245_0 Ribosomal protein S1 K02945 - - 5.496e-219 692.0
DTH2_k127_185245_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
DTH2_k127_187274_0 Lipoxygenase homology 2 (beta barrel) domain K14073,K14074,K14075 GO:0003674,GO:0003824,GO:0004620,GO:0004806,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006968,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009605,GO:0009719,GO:0009725,GO:0009791,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0012505,GO:0012506,GO:0014070,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019374,GO:0019376,GO:0019377,GO:0019637,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031667,GO:0031960,GO:0031982,GO:0032094,GO:0032501,GO:0032502,GO:0033993,GO:0042221,GO:0042588,GO:0042589,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043434,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044258,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0046434,GO:0046466,GO:0046872,GO:0047372,GO:0047714,GO:0048545,GO:0048856,GO:0050896,GO:0051384,GO:0052689,GO:0071704,GO:0097708,GO:0098588,GO:0098805,GO:0099503,GO:1901135,GO:1901136,GO:1901575,GO:1901652,GO:1901698,GO:1901700,GO:1903509 3.1.1.3 0.000005157 58.0
DTH2_k127_1893888_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 591.0
DTH2_k127_1893888_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 321.0
DTH2_k127_1893888_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000008386 235.0
DTH2_k127_1893888_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000001047 191.0
DTH2_k127_1893888_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000704 164.0
DTH2_k127_1893888_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000002928 151.0
DTH2_k127_1893888_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000209 130.0
DTH2_k127_1905835_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 379.0
DTH2_k127_1905835_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 329.0
DTH2_k127_1905835_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000008991 259.0
DTH2_k127_192041_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 380.0
DTH2_k127_192041_1 PFAM type II and III secretion system protein K02666 - - 0.00000000000000001804 97.0
DTH2_k127_192041_2 Belongs to the GSP D family K02280 - - 0.0000000000001943 84.0
DTH2_k127_192041_3 Zinc metalloprotease (Elastase) K20274 - - 0.000000000003227 74.0
DTH2_k127_1950886_0 Belongs to the glycosyl hydrolase 2 family K01192,K15855 - 3.2.1.165,3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 471.0
DTH2_k127_1950886_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 378.0
DTH2_k127_1950886_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 332.0
DTH2_k127_1950886_3 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000003941 235.0
DTH2_k127_1950886_4 Periplasmic binding proteins and sugar binding domain of LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000008897 222.0
DTH2_k127_1950886_6 - - - - 0.000000000000000000000000000001321 140.0
DTH2_k127_1950886_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000004458 116.0
DTH2_k127_1950886_8 Two component signalling adaptor domain K03408 - - 0.0000000000003104 71.0
DTH2_k127_1950886_9 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0002152 45.0
DTH2_k127_1958450_0 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 374.0
DTH2_k127_1961721_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
DTH2_k127_1961721_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000001539 183.0
DTH2_k127_196243_0 SRP54-type protein, helical bundle domain K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 492.0
DTH2_k127_196243_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 386.0
DTH2_k127_196243_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 390.0
DTH2_k127_196243_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 352.0
DTH2_k127_196243_4 Protein of unknown function (DUF1559) K02456 - - 0.00000001209 65.0
DTH2_k127_1989121_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.653e-195 634.0
DTH2_k127_1989121_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000001107 139.0
DTH2_k127_1997444_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 293.0
DTH2_k127_1997444_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000009133 184.0
DTH2_k127_1997444_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000003731 124.0
DTH2_k127_1997444_3 - - - - 0.0000000000008583 78.0
DTH2_k127_200477_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.262e-204 661.0
DTH2_k127_2034070_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
DTH2_k127_2034070_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000006348 187.0
DTH2_k127_2034070_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000001682 75.0
DTH2_k127_2034070_3 dihydroceramide glucosyltransferase activity K00720 GO:0000139,GO:0002119,GO:0002164,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006677,GO:0006678,GO:0006679,GO:0006687,GO:0006688,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0008120,GO:0008150,GO:0008152,GO:0008194,GO:0008544,GO:0008610,GO:0009056,GO:0009058,GO:0009247,GO:0009719,GO:0009791,GO:0009888,GO:0009987,GO:0010033,GO:0010453,GO:0010470,GO:0010941,GO:0012505,GO:0016020,GO:0016042,GO:0016740,GO:0016757,GO:0016758,GO:0019377,GO:0022603,GO:0023052,GO:0030148,GO:0030149,GO:0031090,GO:0031984,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0034641,GO:0035251,GO:0040008,GO:0040014,GO:0042175,GO:0042221,GO:0042659,GO:0042661,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045995,GO:0046466,GO:0046467,GO:0046476,GO:0046479,GO:0046513,GO:0046527,GO:0048519,GO:0048523,GO:0048638,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051239,GO:0051716,GO:0060341,GO:0060548,GO:0065007,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071944,GO:0098588,GO:0098791,GO:0098827,GO:1901048,GO:1901135,GO:1901136,GO:1901137,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903509,GO:1903827,GO:1904375,GO:1904508,GO:1905475,GO:1905770,GO:1905902,GO:2000026,GO:2000027,GO:2000380 2.4.1.80 0.0000005872 55.0
DTH2_k127_2034070_5 hydrolase family 65, central catalytic K00691 - 2.4.1.8 0.0005623 44.0
DTH2_k127_2053265_0 TIGRFAM ribonuclease, Rne Rng family K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 402.0
DTH2_k127_2053265_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 289.0
DTH2_k127_2053265_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000007296 174.0
DTH2_k127_2059520_0 Cytidylate kinase-like family - - - 0.000000000000000004115 93.0
DTH2_k127_2059520_2 H subunit K02107 - - 0.00001801 51.0
DTH2_k127_2070913_0 3-beta hydroxysteroid dehydrogenase/isomerase family K03274 - 5.1.3.20 0.000000000000000001857 86.0
DTH2_k127_2070913_1 Nucleotidyltransferase substrate binding protein like - - - 0.000000000000000002269 89.0
DTH2_k127_2070913_2 Nucleotidyltransferase domain - - - 0.000000000000000002486 88.0
DTH2_k127_2083418_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 323.0
DTH2_k127_2083418_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 303.0
DTH2_k127_2083418_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.00000000000000000000000000000000000000000000000000000000000000000003522 238.0
DTH2_k127_2083418_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000009292 240.0
DTH2_k127_2083418_4 FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000001163 220.0
DTH2_k127_2083418_5 - - - - 0.00000000000000000000000000000472 124.0
DTH2_k127_2083418_6 Helix-turn-helix domain - - - 0.00000000000000002936 91.0
DTH2_k127_2083418_7 retrograde transport, endosome to Golgi - - - 0.0000002198 59.0
DTH2_k127_2089819_0 60 kDa outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 346.0
DTH2_k127_2089819_1 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 305.0
DTH2_k127_2089819_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
DTH2_k127_2089819_3 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000001274 177.0
DTH2_k127_2096363_0 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 527.0
DTH2_k127_2096363_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 373.0
DTH2_k127_2096363_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000001877 95.0
DTH2_k127_2107136_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.823e-220 708.0
DTH2_k127_2107136_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000004117 79.0
DTH2_k127_2121173_0 Major facilitator Superfamily K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003652 294.0
DTH2_k127_2121173_1 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 0.0000000000004708 69.0
DTH2_k127_2121173_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000004176 60.0
DTH2_k127_21258_0 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 507.0
DTH2_k127_21258_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000001927 156.0
DTH2_k127_21258_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000004874 66.0
DTH2_k127_218753_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 348.0
DTH2_k127_218753_1 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 295.0
DTH2_k127_218753_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005086 289.0
DTH2_k127_221401_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 299.0
DTH2_k127_221401_1 COG0226 ABC-type phosphate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000009762 175.0
DTH2_k127_221401_2 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000001318 135.0
DTH2_k127_221401_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000007257 78.0
DTH2_k127_2219707_0 aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 504.0
DTH2_k127_2219707_1 nucleic acid binding OB-fold tRNA helicase-type K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.0000000000000000000000006351 112.0
DTH2_k127_2219730_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 522.0
DTH2_k127_2219730_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 407.0
DTH2_k127_2219730_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000002702 123.0
DTH2_k127_2219730_3 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000001731 108.0
DTH2_k127_2219730_4 Polysaccharide biosynthesis protein - - - 0.00003401 48.0
DTH2_k127_2252766_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 295.0
DTH2_k127_2252766_1 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000002244 212.0
DTH2_k127_2252766_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00002705 47.0
DTH2_k127_2275077_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 526.0
DTH2_k127_2275077_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 341.0
DTH2_k127_2275077_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000005736 139.0
DTH2_k127_2383980_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 355.0
DTH2_k127_2383980_1 Domain of unknown function (DUF4136) - - - 0.0000002158 60.0
DTH2_k127_241456_0 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 458.0
DTH2_k127_241456_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
DTH2_k127_241456_2 Sugar-binding cellulase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 362.0
DTH2_k127_241456_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000217 156.0
DTH2_k127_241456_4 - - - - 0.000000000000000000000000000001714 140.0
DTH2_k127_241456_5 Bacterial regulatory proteins, tetR family - - - 0.00000000001942 69.0
DTH2_k127_241456_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000002209 62.0
DTH2_k127_2423556_0 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000003859 176.0
DTH2_k127_2423556_1 Penicillinase repressor - - - 0.0000000000000000003934 93.0
DTH2_k127_2423556_2 Tfp pilus assembly protein FimV - - - 0.000000000000000004583 95.0
DTH2_k127_2423556_3 Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle K14211 GO:0001101,GO:0001568,GO:0001666,GO:0001944,GO:0001974,GO:0003007,GO:0003008,GO:0003013,GO:0003151,GO:0003170,GO:0003176,GO:0003179,GO:0003180,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007275,GO:0007507,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0007585,GO:0008015,GO:0008064,GO:0008150,GO:0008283,GO:0009410,GO:0009605,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009887,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0014070,GO:0014706,GO:0016043,GO:0022607,GO:0030023,GO:0030029,GO:0030036,GO:0030038,GO:0030198,GO:0030832,GO:0030833,GO:0031012,GO:0031032,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031960,GO:0032271,GO:0032501,GO:0032502,GO:0032526,GO:0032535,GO:0032870,GO:0032956,GO:0032970,GO:0033043,GO:0033273,GO:0033554,GO:0033591,GO:0033993,GO:0034284,GO:0035690,GO:0035904,GO:0036293,GO:0036294,GO:0036296,GO:0042221,GO:0042493,GO:0043062,GO:0043149,GO:0043254,GO:0044085,GO:0044087,GO:0044344,GO:0044420,GO:0044421,GO:0046688,GO:0048251,GO:0048513,GO:0048545,GO:0048731,GO:0048771,GO:0048856,GO:0050789,GO:0050794,GO:0050840,GO:0050896,GO:0051017,GO:0051128,GO:0051384,GO:0051493,GO:0051716,GO:0055093,GO:0060537,GO:0060538,GO:0060840,GO:0061061,GO:0061572,GO:0065007,GO:0065008,GO:0070482,GO:0070848,GO:0070887,GO:0071229,GO:0071241,GO:0071248,GO:0071280,GO:0071295,GO:0071298,GO:0071300,GO:0071310,GO:0071322,GO:0071326,GO:0071363,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071453,GO:0071456,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071559,GO:0071560,GO:0071774,GO:0071840,GO:0071953,GO:0072358,GO:0072359,GO:0085029,GO:0090066,GO:0097327,GO:0097435,GO:0097493,GO:0110053,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902903,GO:1905314 - 0.0000000002361 63.0
DTH2_k127_2434085_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 1.178e-201 642.0
DTH2_k127_2434085_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 609.0
DTH2_k127_2434085_10 nitrogen fixation - - - 0.0000000000000000000000000000000000005923 144.0
DTH2_k127_2434085_11 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000001464 153.0
DTH2_k127_2434085_12 PFAM response regulator receiver K11329 - - 0.0000000000000000000000000005649 119.0
DTH2_k127_2434085_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000004142 96.0
DTH2_k127_2434085_14 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000008505 77.0
DTH2_k127_2434085_15 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - 0.000000003617 63.0
DTH2_k127_2434085_16 Tetratricopeptide repeat - - - 0.00000847 58.0
DTH2_k127_2434085_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
DTH2_k127_2434085_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004865 246.0
DTH2_k127_2434085_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000405 237.0
DTH2_k127_2434085_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000003363 231.0
DTH2_k127_2434085_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000002522 210.0
DTH2_k127_2434085_7 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000007222 173.0
DTH2_k127_2434085_8 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000001019 159.0
DTH2_k127_2434085_9 Belongs to the GSP D family K02666 - - 0.00000000000000000000000000000000000006844 152.0
DTH2_k127_2463244_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 491.0
DTH2_k127_2463244_1 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.0000000000000000000000000000000000000001827 154.0
DTH2_k127_2463244_2 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000001896 158.0
DTH2_k127_2463244_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000009048 102.0
DTH2_k127_2463244_4 late embryogenesis abundant protein - - - 0.000000000000000000000273 103.0
DTH2_k127_251833_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 333.0
DTH2_k127_251833_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 298.0
DTH2_k127_251833_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000000000005291 197.0
DTH2_k127_251833_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000003842 62.0
DTH2_k127_2561118_0 Glycosyl hydrolases family 38 C-terminal domain K15524 - 3.2.1.170 5.299e-257 823.0
DTH2_k127_2561118_1 Fibronectin type III domain - - - 0.000000006279 59.0
DTH2_k127_2561118_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.000000007438 57.0
DTH2_k127_2582958_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 385.0
DTH2_k127_2582958_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 291.0
DTH2_k127_2582958_2 PFAM nucleic acid binding, OB-fold, tRNA - - - 0.00001059 56.0
DTH2_k127_2593558_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 522.0
DTH2_k127_2593558_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
DTH2_k127_2593558_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
DTH2_k127_2593558_3 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000001607 167.0
DTH2_k127_2593558_4 - - - - 0.0000001749 55.0
DTH2_k127_2594081_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 620.0
DTH2_k127_2594081_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
DTH2_k127_2594081_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 379.0
DTH2_k127_2594081_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 370.0
DTH2_k127_2594081_4 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
DTH2_k127_2594081_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000003377 67.0
DTH2_k127_2594081_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000002518 67.0
DTH2_k127_2611832_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 492.0
DTH2_k127_2616617_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 604.0
DTH2_k127_2616617_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 367.0
DTH2_k127_2616617_2 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 348.0
DTH2_k127_2616617_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 335.0
DTH2_k127_2616617_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001702 269.0
DTH2_k127_2616617_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 254.0
DTH2_k127_2616617_6 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000003903 188.0
DTH2_k127_2616617_7 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000001871 131.0
DTH2_k127_2616617_8 polygalacturonase activity - - - 0.000000000000000000004781 98.0
DTH2_k127_2616617_9 - - - - 0.000000001106 61.0
DTH2_k127_2666709_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000001797 214.0
DTH2_k127_2666709_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000293 218.0
DTH2_k127_2666709_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000007205 116.0
DTH2_k127_2666709_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000003346 100.0
DTH2_k127_2712357_0 with chaperone activity ATP-binding K03696 - - 6.658e-266 829.0
DTH2_k127_2712357_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 450.0
DTH2_k127_2712357_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
DTH2_k127_2712357_3 adenylate kinase activity K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
DTH2_k127_2712357_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000003701 183.0
DTH2_k127_2712357_5 PFAM Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000002812 141.0
DTH2_k127_2712357_6 Pyruvate phosphate dikinase - - - 0.00000000000000000000000004464 117.0
DTH2_k127_2764873_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 435.0
DTH2_k127_2764873_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000004873 183.0
DTH2_k127_2790132_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000004335 253.0
DTH2_k127_2790132_1 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000001157 144.0
DTH2_k127_2798438_0 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 584.0
DTH2_k127_2798438_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 534.0
DTH2_k127_2798438_2 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000007359 235.0
DTH2_k127_2798438_3 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000001859 167.0
DTH2_k127_2798438_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000005722 132.0
DTH2_k127_2798438_5 - - - - 0.0000000000000000000000000002391 122.0
DTH2_k127_2798438_6 nucleotidyltransferase activity K07075 - - 0.00000000000000005857 84.0
DTH2_k127_286028_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 516.0
DTH2_k127_286028_1 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 368.0
DTH2_k127_2904118_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000148 267.0
DTH2_k127_2904118_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K05881 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000007194 263.0
DTH2_k127_293243_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 501.0
DTH2_k127_293243_1 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 394.0
DTH2_k127_293243_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000004571 136.0
DTH2_k127_2949169_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 404.0
DTH2_k127_2949169_1 - - - - 0.000000000000000000000003372 108.0
DTH2_k127_2949169_2 - - - - 0.0000000000002886 75.0
DTH2_k127_2957505_0 PFAM hexokinase K00844 - 2.7.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 444.0
DTH2_k127_2957505_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 438.0
DTH2_k127_2957505_2 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 419.0
DTH2_k127_2957505_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 388.0
DTH2_k127_2957505_4 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000001768 161.0
DTH2_k127_3001999_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 409.0
DTH2_k127_3001999_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
DTH2_k127_3001999_2 DJ-1/PfpI family K03152,K05520,K05687,K12132 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000007411 235.0
DTH2_k127_3001999_3 ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000004528 234.0
DTH2_k127_3001999_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000001045 210.0
DTH2_k127_3001999_5 Protein of unknown function (DUF2905) - - - 0.00000000005894 65.0
DTH2_k127_3005451_0 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 317.0
DTH2_k127_3005451_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
DTH2_k127_3005451_2 Lipoprotein - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000001892 62.0
DTH2_k127_3005451_3 Curli production assembly/transport component CsgG - - - 0.0001101 52.0
DTH2_k127_3007765_0 Hypothetical glycosyl hydrolase 6 - - - 1.846e-263 827.0
DTH2_k127_3007765_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 353.0
DTH2_k127_3007765_2 Major facilitator Superfamily K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 312.0
DTH2_k127_3007765_3 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000004649 223.0
DTH2_k127_3007765_4 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000001893 220.0
DTH2_k127_3008837_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
DTH2_k127_3008837_1 Pyruvate carboxyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 0.000000000000000000000000000000000000000000006443 167.0
DTH2_k127_3008837_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.00000000000000005117 91.0
DTH2_k127_3026871_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
DTH2_k127_3026871_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 280.0
DTH2_k127_3026871_2 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000003221 179.0
DTH2_k127_3026871_3 ABC-type transport auxiliary lipoprotein component - - - 0.000000000003747 75.0
DTH2_k127_3084695_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 587.0
DTH2_k127_3084695_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 327.0
DTH2_k127_3084695_2 Rubrerythrin - - - 0.00001815 49.0
DTH2_k127_3086750_0 Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 546.0
DTH2_k127_3086750_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 516.0
DTH2_k127_3086750_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 462.0
DTH2_k127_3086750_3 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 407.0
DTH2_k127_3086750_4 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000000000001285 154.0
DTH2_k127_3086750_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000002452 69.0
DTH2_k127_3099302_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 548.0
DTH2_k127_3099302_1 Trp repressor protein K03720 - - 0.00000000000000002673 85.0
DTH2_k127_3099302_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K06378 - - 0.0002311 48.0
DTH2_k127_3127870_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 4.793e-251 785.0
DTH2_k127_3127870_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.492e-248 784.0
DTH2_k127_3127870_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
DTH2_k127_3127870_3 signal peptidase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001064 233.0
DTH2_k127_3127870_4 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000003224 176.0
DTH2_k127_3127870_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000008863 156.0
DTH2_k127_3127870_6 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000005287 106.0
DTH2_k127_3127870_7 - - - - 0.000000000000000000162 93.0
DTH2_k127_3127870_8 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00000000000005165 74.0
DTH2_k127_3158384_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000006951 267.0
DTH2_k127_3158384_1 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000007509 192.0
DTH2_k127_3185576_0 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 297.0
DTH2_k127_3185576_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000003947 225.0
DTH2_k127_3185576_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000001053 198.0
DTH2_k127_3185576_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000002013 165.0
DTH2_k127_3185576_4 Putative regulatory protein - - - 0.0000000197 57.0
DTH2_k127_3201824_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 312.0
DTH2_k127_3201824_1 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
DTH2_k127_3201824_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000001226 183.0
DTH2_k127_3201824_3 Pfam Response regulator receiver - - - 0.000000000000000000000000000000000000001783 151.0
DTH2_k127_3201824_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000001437 135.0
DTH2_k127_3201824_5 Response regulator, receiver - - - 0.000000000002195 73.0
DTH2_k127_3201824_6 ThiS family K03154 - - 0.0000003157 54.0
DTH2_k127_3280036_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 327.0
DTH2_k127_3280036_1 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000002243 205.0
DTH2_k127_3280036_2 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000002741 86.0
DTH2_k127_3283017_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1637.0
DTH2_k127_3283017_1 Belongs to the CarB family K01955 - 6.3.5.5 3.356e-279 869.0
DTH2_k127_3283017_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 526.0
DTH2_k127_3283017_3 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
DTH2_k127_3284890_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 584.0
DTH2_k127_3284890_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 475.0
DTH2_k127_3284890_2 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
DTH2_k127_3284890_3 Pfam ABC K02068 - - 0.0000000000000000000000000000000000000000000000001121 187.0
DTH2_k127_3325167_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 2.44e-281 876.0
DTH2_k127_3325167_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.435e-268 840.0
DTH2_k127_3325167_2 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 511.0
DTH2_k127_3325167_3 PFAM Sporulation stage II, protein E C-terminal - - - 0.0000000000000000000000000000000000000000003755 171.0
DTH2_k127_3325167_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000001189 158.0
DTH2_k127_3363364_0 Transposase IS200 like - - - 0.00000000000000000000000000000000000000002244 158.0
DTH2_k127_3363364_1 Transcriptional K07729 - - 0.0000000000000000001845 90.0
DTH2_k127_3363364_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000003779 60.0
DTH2_k127_3363506_0 Carbohydrate kinase, FGGY family protein K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 620.0
DTH2_k127_3363506_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 355.0
DTH2_k127_3363506_10 Domain of unknown function (DUF1844) - - - 0.000000000000001904 81.0
DTH2_k127_3363506_11 response to heat K07090 - - 0.00000000001872 67.0
DTH2_k127_3363506_12 Sulfite exporter TauE/SafE K07090 - - 0.00000002512 63.0
DTH2_k127_3363506_13 COG1360 Flagellar motor protein K02557 - - 0.0003764 51.0
DTH2_k127_3363506_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000004078 235.0
DTH2_k127_3363506_3 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000001391 209.0
DTH2_k127_3363506_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002747 171.0
DTH2_k127_3363506_5 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000002273 151.0
DTH2_k127_3363506_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000007237 141.0
DTH2_k127_3363506_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000003196 127.0
DTH2_k127_3363506_8 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000001001 111.0
DTH2_k127_3363506_9 - - - - 0.00000000000000000003053 99.0
DTH2_k127_3372654_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.808e-201 640.0
DTH2_k127_3372654_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 502.0
DTH2_k127_3372654_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 291.0
DTH2_k127_3372654_3 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006887 247.0
DTH2_k127_3372654_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000006021 218.0
DTH2_k127_3372654_5 Histidine kinase - - - 0.00000000000000000000000000000000000434 147.0
DTH2_k127_3372654_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000001118 125.0
DTH2_k127_3372654_7 haemagglutination activity domain - - - 0.00000000000000000000000000001222 135.0
DTH2_k127_3372654_8 COG1253 Hemolysins and related - - - 0.0000000000000000000000006942 117.0
DTH2_k127_342934_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 506.0
DTH2_k127_342934_1 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 357.0
DTH2_k127_342934_10 CTP reductase activity K21636 - 1.1.98.6 0.00000006013 61.0
DTH2_k127_342934_2 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 346.0
DTH2_k127_342934_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 317.0
DTH2_k127_342934_4 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006822 256.0
DTH2_k127_342934_5 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000001841 186.0
DTH2_k127_342934_6 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001995 188.0
DTH2_k127_342934_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000002318 169.0
DTH2_k127_342934_8 UPF0056 membrane protein K05595 - - 0.0000000000000000000000004274 112.0
DTH2_k127_342934_9 Alternative locus ID K06995 - - 0.00000000000000000000004374 102.0
DTH2_k127_3440836_1 Transcriptional regulator, AraC family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009931 283.0
DTH2_k127_3440836_2 symporter activity K03307 - - 0.0000000000000000000000000000001363 126.0
DTH2_k127_3542_0 Uncharacterized conserved protein (DUF2075) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 563.0
DTH2_k127_3542_1 Raffinose synthase or seed imbibition protein Sip1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 497.0
DTH2_k127_3542_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 361.0
DTH2_k127_3542_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000199 222.0
DTH2_k127_3542_4 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000001481 151.0
DTH2_k127_3542_5 Endoglucanase K01218 - 3.2.1.78 0.000000000000000000000000000000000001763 160.0
DTH2_k127_3542_6 Carbohydrate binding domain - - - 0.000001017 58.0
DTH2_k127_3561253_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 453.0
DTH2_k127_3561253_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 442.0
DTH2_k127_3561253_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000006462 153.0
DTH2_k127_3561253_3 cell redox homeostasis K02199 - - 0.0000000000000000000005328 112.0
DTH2_k127_3561253_4 Protein of unknown function (DUF2752) - - - 0.000001397 56.0
DTH2_k127_3599985_0 Beta-xylosidase K22268 - 3.2.1.37 9.554e-276 864.0
DTH2_k127_3599985_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 509.0
DTH2_k127_3599985_2 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 320.0
DTH2_k127_3599985_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000319 242.0
DTH2_k127_3609381_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 516.0
DTH2_k127_3609381_1 TIGRFAM ribonuclease, Rne Rng family K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000006816 179.0
DTH2_k127_3609381_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768,K02806 - 2.7.1.202 0.00000000000000000000000000000002335 131.0
DTH2_k127_3609381_3 protein conserved in bacteria (DUF2344) - - - 0.000000000001515 76.0
DTH2_k127_3609381_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000004643 70.0
DTH2_k127_3609381_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000009457 70.0
DTH2_k127_3645825_0 MMPL family K07003 - - 3.872e-259 823.0
DTH2_k127_3645825_1 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 375.0
DTH2_k127_3645825_2 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
DTH2_k127_3645825_3 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000007994 141.0
DTH2_k127_3687177_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 394.0
DTH2_k127_3687177_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
DTH2_k127_3687177_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000002268 204.0
DTH2_k127_3687177_3 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000001855 157.0
DTH2_k127_3687177_4 ERAD pathway K07126,K14026 - - 0.000000001503 59.0
DTH2_k127_3687177_5 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000003538 57.0
DTH2_k127_3692780_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 439.0
DTH2_k127_3692780_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 294.0
DTH2_k127_3692780_10 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806,K07646 - 2.7.1.202,2.7.13.3 0.00001554 50.0
DTH2_k127_3692780_2 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000001364 228.0
DTH2_k127_3692780_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000003069 190.0
DTH2_k127_3692780_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000001114 183.0
DTH2_k127_3692780_5 Type II secretion system (T2SS), protein F K12278 - - 0.0000000000000000000000000006285 125.0
DTH2_k127_3692780_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000158 113.0
DTH2_k127_3692780_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000002927 80.0
DTH2_k127_3692780_8 virulence factor Mce family protein K02067 - - 0.0000000000004655 79.0
DTH2_k127_3692780_9 helix_turn_helix, mercury resistance - - - 0.000001625 53.0
DTH2_k127_3697488_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 402.0
DTH2_k127_3697488_1 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000002274 90.0
DTH2_k127_3701366_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001621 207.0
DTH2_k127_3701366_1 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000002717 131.0
DTH2_k127_3701366_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000001246 85.0
DTH2_k127_3714810_0 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000008876 179.0
DTH2_k127_3714810_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000064 171.0
DTH2_k127_3714810_2 - - - - 0.00000000000000000000003599 101.0
DTH2_k127_3714810_3 Putative prokaryotic signal transducing protein - - - 0.0001107 49.0
DTH2_k127_3825472_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 499.0
DTH2_k127_3825472_1 Saccharopine dehydrogenase K00290,K13746 - 1.5.1.43,1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 415.0
DTH2_k127_3825472_2 COG2211 Na melibiose symporter and related transporters K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 409.0
DTH2_k127_3825472_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000009831 194.0
DTH2_k127_3838042_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 3.013e-238 739.0
DTH2_k127_3838042_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003637 242.0
DTH2_k127_3839668_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 614.0
DTH2_k127_3839668_1 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 467.0
DTH2_k127_3839668_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 337.0
DTH2_k127_3839668_3 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
DTH2_k127_3839668_4 - - - - 0.0000000000000000000000000000000000000000000006206 169.0
DTH2_k127_3839668_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000006388 61.0
DTH2_k127_3845759_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 353.0
DTH2_k127_3845759_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002859 270.0
DTH2_k127_3845759_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000462 249.0
DTH2_k127_3845759_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000007049 223.0
DTH2_k127_3845759_4 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000462 85.0
DTH2_k127_3845759_5 MacB-like periplasmic core domain K09808 - - 0.0000003296 62.0
DTH2_k127_3848068_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 442.0
DTH2_k127_3848068_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 413.0
DTH2_k127_3848068_2 rna polymerase alpha K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 307.0
DTH2_k127_3848068_3 TIGRFAM 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000122 183.0
DTH2_k127_3848068_4 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000002016 162.0
DTH2_k127_3848068_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000002183 147.0
DTH2_k127_3848068_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000001464 104.0
DTH2_k127_3848068_7 Preprotein translocase subunit K03210 - - 0.00000000009155 68.0
DTH2_k127_3848068_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.000000001461 67.0
DTH2_k127_3848068_9 Domain of unknown function (DUF4190) - - - 0.00001008 56.0
DTH2_k127_3859878_0 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
DTH2_k127_3859878_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000001919 88.0
DTH2_k127_3859878_2 Polymer-forming cytoskeletal - - - 0.0000000003077 72.0
DTH2_k127_3859878_3 Pilus assembly protein PilX - - - 0.000000001672 70.0
DTH2_k127_3882194_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 422.0
DTH2_k127_3882194_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000005542 154.0
DTH2_k127_3882194_2 UPF0210 protein K09157 - - 0.0000000004224 61.0
DTH2_k127_3882194_3 L-iditol 2-dehydrogenase activity K00008 GO:0008150,GO:0030431,GO:0032501 1.1.1.14 0.00000007044 56.0
DTH2_k127_3882194_4 - - - - 0.0008264 43.0
DTH2_k127_3882632_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000002708 233.0
DTH2_k127_3882632_1 - - - - 0.000000009571 67.0
DTH2_k127_3923_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.068e-268 838.0
DTH2_k127_3923_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000426 57.0
DTH2_k127_3933836_0 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 1.928e-197 621.0
DTH2_k127_3933836_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 326.0
DTH2_k127_3933836_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 326.0
DTH2_k127_394118_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
DTH2_k127_394118_1 Cellulose biosynthesis protein BcsQ K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
DTH2_k127_394118_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000001118 167.0
DTH2_k127_394118_3 - - - - 0.0000000000002513 81.0
DTH2_k127_394118_4 transcriptional - - - 0.00000004199 57.0
DTH2_k127_3964174_0 COG0639 Diadenosine tetraphosphatase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 286.0
DTH2_k127_3964174_1 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000001054 196.0
DTH2_k127_3964174_2 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000002698 127.0
DTH2_k127_3964174_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000002763 93.0
DTH2_k127_3964174_4 Nucleotidyltransferase domain - - - 0.00000005386 58.0
DTH2_k127_4036453_0 COG0147 Anthranilate para-aminobenzoate synthases component I K01657,K13503 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 344.0
DTH2_k127_4036453_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 315.0
DTH2_k127_4036453_2 Anthranilate synthase K01658 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000002296 211.0
DTH2_k127_4036453_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000005584 185.0
DTH2_k127_4058577_0 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 460.0
DTH2_k127_4058577_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 350.0
DTH2_k127_4058577_2 Alcohol dehydrogenase GroES-like domain K19956 - - 0.0000000000000000000000000000000000000000002434 174.0
DTH2_k127_4058577_3 mannitol metabolic process K00009 - 1.1.1.17 0.00000000000001017 76.0
DTH2_k127_4058624_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 4.387e-303 952.0
DTH2_k127_4058624_1 promotes GTP-dependent translocation of the ribosome during translation K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
DTH2_k127_4103578_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
DTH2_k127_4103578_1 Protein of unknown function (DUF3313) - - - 0.0000001254 61.0
DTH2_k127_410936_0 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
DTH2_k127_410936_1 COG1283 Na phosphate symporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 319.0
DTH2_k127_410936_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 299.0
DTH2_k127_410936_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 292.0
DTH2_k127_410936_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001388 250.0
DTH2_k127_410936_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000002163 241.0
DTH2_k127_4109656_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 8.059e-236 745.0
DTH2_k127_4109656_1 Protein of unknown function, DUF485 - - - 0.000000000000000000001565 98.0
DTH2_k127_4122455_0 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009317 258.0
DTH2_k127_4122455_1 FR47-like protein K03826,K22477 - 2.3.1.1 0.0000000000000000000000000000000000000000000133 166.0
DTH2_k127_4122455_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000004711 164.0
DTH2_k127_4122455_3 cyclopropane-fatty-acyl-phospholipid synthase K00574,K07154,K14369,K15257,K18534 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249 2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1 0.00000006764 59.0
DTH2_k127_4122455_4 Acetyltransferase (GNAT) domain - - - 0.00002557 46.0
DTH2_k127_4127594_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.708e-317 986.0
DTH2_k127_4127594_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.411e-231 721.0
DTH2_k127_4127594_10 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000375 93.0
DTH2_k127_4127594_11 membrane K00860,K00956 - 2.7.1.25,2.7.7.4 0.000000000000004472 77.0
DTH2_k127_4127594_12 Protein of unknown function (DUF3034) - - - 0.00000000000003847 83.0
DTH2_k127_4127594_13 DNA polymerase Ligase (LigD) - - - 0.00000000000004963 77.0
DTH2_k127_4127594_14 Uncharacterized small protein (DUF2292) - - - 0.00003167 49.0
DTH2_k127_4127594_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 5.252e-205 654.0
DTH2_k127_4127594_3 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 501.0
DTH2_k127_4127594_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 466.0
DTH2_k127_4127594_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 428.0
DTH2_k127_4127594_6 belongs to the CobB CobQ family K13788 GO:0005575,GO:0005576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 309.0
DTH2_k127_4127594_7 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 301.0
DTH2_k127_4127594_8 Nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 0.000000000000000000000000000000000000000002146 172.0
DTH2_k127_4127594_9 Transcriptional regulator - - - 0.00000000000000000000000000000000002291 139.0
DTH2_k127_4142813_0 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 348.0
DTH2_k127_4142813_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000003046 153.0
DTH2_k127_4142813_2 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000000214 128.0
DTH2_k127_4142813_3 protein with conserved CXXC pairs K19411 - - 0.00000001602 57.0
DTH2_k127_4148211_0 Required for chromosome condensation and partitioning K03529 - - 1.042e-194 650.0
DTH2_k127_4148211_1 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 574.0
DTH2_k127_4148211_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 423.0
DTH2_k127_4148211_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
DTH2_k127_4148211_4 - - - - 0.00000000000000000000000000000000000000000001827 177.0
DTH2_k127_4148211_5 PFAM Peptidase M16 - - - 0.00000000000000007296 86.0
DTH2_k127_4148211_6 serine protease K07403 - - 0.00000000001886 76.0
DTH2_k127_4148211_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000002313 70.0
DTH2_k127_4148211_8 NfeD-like C-terminal, partner-binding K07403 - - 0.0003433 53.0
DTH2_k127_4150784_0 S1, RNA binding domain K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 562.0
DTH2_k127_4150784_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000001137 240.0
DTH2_k127_4150784_2 COG4969 Tfp pilus assembly protein, major pilin PilA K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000002653 55.0
DTH2_k127_4150999_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001643 274.0
DTH2_k127_4150999_1 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000004324 230.0
DTH2_k127_4150999_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000001053 121.0
DTH2_k127_4150999_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001897 92.0
DTH2_k127_4172656_0 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000001263 169.0
DTH2_k127_4172656_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000003431 52.0
DTH2_k127_4178401_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
DTH2_k127_4178401_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
DTH2_k127_4178401_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000006832 227.0
DTH2_k127_4178401_3 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
DTH2_k127_4178401_4 Passenger-associated-transport-repeat - - - 0.00000001867 63.0
DTH2_k127_4189303_0 Galactose mutarotase-like K01187,K01811 - 3.2.1.177,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 535.0
DTH2_k127_4189303_1 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 436.0
DTH2_k127_4189303_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 392.0
DTH2_k127_4189303_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000002764 250.0
DTH2_k127_4189303_4 zinc-ribbon domain - - - 0.0000000000000001071 85.0
DTH2_k127_4189303_5 Transcription factor zinc-finger - - - 0.00000000003844 70.0
DTH2_k127_4189303_6 glycosyl transferase family 2 K20444 - - 0.0000000592 63.0
DTH2_k127_4214286_0 TIGRFAM amino acid carrier protein K03310 - - 1.541e-196 621.0
DTH2_k127_4214286_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 389.0
DTH2_k127_4214286_2 PAC2 family K07159 - - 0.000000000000000000000001886 113.0
DTH2_k127_4214286_3 Protein of unknown function (DUF3568) - - - 0.0000000000003719 74.0
DTH2_k127_4225833_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000005666 238.0
DTH2_k127_4225833_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000002515 53.0
DTH2_k127_4254830_0 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000003173 224.0
DTH2_k127_4254830_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000005624 220.0
DTH2_k127_4254830_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000005569 158.0
DTH2_k127_4254830_3 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000002202 66.0
DTH2_k127_4254830_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000001419 66.0
DTH2_k127_4254830_5 Tetratricopeptide repeat - - - 0.00000008582 64.0
DTH2_k127_4268790_0 ATPase activity K06027 - 3.6.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 612.0
DTH2_k127_4268790_1 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 571.0
DTH2_k127_4268790_3 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000964 176.0
DTH2_k127_4268790_5 Protein of unknown function (DUF2997) - - - 0.000000000005273 68.0
DTH2_k127_4268901_0 Electron transfer flavoprotein, alpha subunit K03522 - - 1.029e-282 884.0
DTH2_k127_4268901_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 5.378e-226 712.0
DTH2_k127_4268901_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100,K03444,K08138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 502.0
DTH2_k127_4268901_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000006282 254.0
DTH2_k127_4268901_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000004541 178.0
DTH2_k127_427634_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 500.0
DTH2_k127_427634_1 Ferritin-like domain - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006283 267.0
DTH2_k127_427634_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
DTH2_k127_427634_3 symporter activity - - - 0.000000000000000000000000000000000000000000000000000000000001541 213.0
DTH2_k127_427634_4 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000003887 207.0
DTH2_k127_427634_5 Belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.0000000000000000000000000000000000000000009378 161.0
DTH2_k127_4317689_0 Beta-galactosidase K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000001961 234.0
DTH2_k127_4317689_1 translation initiation factor activity K01448,K07315,K12308,K21000,K21470 - 3.1.3.3,3.2.1.23,3.5.1.28 0.000000000000000000002838 104.0
DTH2_k127_4318567_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 547.0
DTH2_k127_4318567_1 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 535.0
DTH2_k127_4318567_2 drug transmembrane transporter activity K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 448.0
DTH2_k127_4318567_3 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 441.0
DTH2_k127_4318567_4 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 430.0
DTH2_k127_4318567_5 PFAM Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001 283.0
DTH2_k127_4318567_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000115 149.0
DTH2_k127_4318567_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002765 75.0
DTH2_k127_436901_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000002429 156.0
DTH2_k127_436901_1 HYR domain - - - 0.00000000000000000005182 103.0
DTH2_k127_4411210_0 Cupin domain K11312 - - 0.000000000000000000000000000000000000000000000113 169.0
DTH2_k127_4411210_1 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000001062 160.0
DTH2_k127_4411210_2 transposase activity - - - 0.0000000000000000000000000001057 124.0
DTH2_k127_441748_0 - - - - 0.00000000000000000000000001073 123.0
DTH2_k127_441748_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000797 102.0
DTH2_k127_4431883_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.846e-228 756.0
DTH2_k127_4431883_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000005971 137.0
DTH2_k127_4431883_3 PFAM glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000135 132.0
DTH2_k127_4431883_4 PFAM TPR repeat-containing protein - - - 0.000000000000000000001023 102.0
DTH2_k127_4431883_5 PFAM TonB-dependent receptor, plug K02014,K16089 - - 0.00000000002079 68.0
DTH2_k127_4431883_6 DegT/DnrJ/EryC1/StrS aminotransferase family K20429 - 2.6.1.33 0.0000000002832 65.0
DTH2_k127_4433035_0 SMART Elongator protein 3 MiaB NifB - - - 2.514e-211 668.0
DTH2_k127_4433035_1 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 438.0
DTH2_k127_4433035_2 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
DTH2_k127_4433035_3 thiol-disulfide isomerase and thioredoxins - - - 0.0000004209 55.0
DTH2_k127_4433035_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.0002138 50.0
DTH2_k127_446224_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 353.0
DTH2_k127_446224_1 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 346.0
DTH2_k127_446224_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 318.0
DTH2_k127_446224_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000001279 178.0
DTH2_k127_4493353_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 334.0
DTH2_k127_4493353_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000000000000006422 93.0
DTH2_k127_4493353_2 Integrase core domain K07482 - - 0.00003726 47.0
DTH2_k127_4558810_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.758e-199 639.0
DTH2_k127_4558810_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000003278 154.0
DTH2_k127_4558810_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768 - 2.7.1.202 0.00000000000000000000000000000000001055 140.0
DTH2_k127_4558810_3 cobalamin binding - - - 0.0000000000000000000000000000000004221 140.0
DTH2_k127_4678071_0 Pfam:N_methyl_2 K02456 - - 0.00000000000000000002054 96.0
DTH2_k127_4678071_1 Pfam:N_methyl_2 K02456 - - 0.0000003712 59.0
DTH2_k127_4680930_0 response regulator receiver K02488 - 2.7.7.65 0.000000000000000000000000000000000000000006581 158.0
DTH2_k127_4680930_1 Subtilase family - - - 0.00000000000002713 86.0
DTH2_k127_4793807_0 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 404.0
DTH2_k127_4793807_1 Tellurite resistance protein TerB - - - 0.000000242 63.0
DTH2_k127_4793807_2 - - - - 0.0000102 55.0
DTH2_k127_4883070_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1308.0
DTH2_k127_4883070_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000002517 241.0
DTH2_k127_4883070_2 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.00000000000000000000000000000000000000000000000000000397 197.0
DTH2_k127_4968062_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 381.0
DTH2_k127_4981193_0 Transposase domain (DUF772) - - - 3.152e-245 763.0
DTH2_k127_5013197_0 Dienelactone hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000592 233.0
DTH2_k127_5013197_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001622 106.0
DTH2_k127_5013197_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000006197 85.0
DTH2_k127_5013197_3 DNA-binding transcription factor activity - - - 0.00000000000000006393 87.0
DTH2_k127_5013601_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 498.0
DTH2_k127_5013601_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000004542 136.0
DTH2_k127_5013601_2 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000007466 91.0
DTH2_k127_5051300_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
DTH2_k127_5051300_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 302.0
DTH2_k127_5051300_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids - - - 0.000000000000000000000000000000000000000000000000000003937 202.0
DTH2_k127_5051300_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000573 134.0
DTH2_k127_5094869_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
DTH2_k127_5094869_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
DTH2_k127_5094869_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001186 273.0
DTH2_k127_5094869_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002173 265.0
DTH2_k127_5094869_4 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000001179 224.0
DTH2_k127_5094869_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000003712 213.0
DTH2_k127_5094869_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000001429 208.0
DTH2_k127_5094869_7 HEPN domain - - - 0.00000000000000000000000000000007476 129.0
DTH2_k127_5094869_8 cheY-homologous receiver domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000000000000135 110.0
DTH2_k127_5094869_9 Nucleotidyltransferase domain - - - 0.000000002064 63.0
DTH2_k127_5101840_0 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000504 214.0
DTH2_k127_5101840_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000002668 173.0
DTH2_k127_5101840_2 ATPase or kinase K06925 - - 0.0000000000000000000000000000007671 126.0
DTH2_k127_5101840_3 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.000000002311 68.0
DTH2_k127_5101840_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0001164 46.0
DTH2_k127_5104912_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.401e-230 724.0
DTH2_k127_5104912_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 308.0
DTH2_k127_5104912_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000003105 117.0
DTH2_k127_5104912_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000009877 108.0
DTH2_k127_5104912_4 Tetratricopeptide repeat - - - 0.000000000135 74.0
DTH2_k127_5116539_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 291.0
DTH2_k127_5116539_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
DTH2_k127_5116539_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000001068 132.0
DTH2_k127_5137241_0 Flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
DTH2_k127_5137241_1 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005707 285.0
DTH2_k127_5137241_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000005713 188.0
DTH2_k127_5137241_3 Flagellar basal body rod FlgEFG protein C-terminal - - - 0.00000000000000000000000000000000009518 142.0
DTH2_k127_5137241_4 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000006201 74.0
DTH2_k127_5137241_5 TIGRFAM flagella basal body P-ring formation protein FlgA K02386 - - 0.00006316 54.0
DTH2_k127_5137241_6 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0005002 48.0
DTH2_k127_5139844_0 ABC transporter - - - 1.051e-215 682.0
DTH2_k127_5139844_1 PFAM D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 399.0
DTH2_k127_5139844_2 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
DTH2_k127_5139844_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00005159 46.0
DTH2_k127_5145277_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 518.0
DTH2_k127_5155623_0 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 608.0
DTH2_k127_5155623_1 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003386 246.0
DTH2_k127_5155623_2 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000003813 154.0
DTH2_k127_5155623_3 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000001135 138.0
DTH2_k127_5155623_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000000000000000499 98.0
DTH2_k127_5155623_5 IS30 family K07482 - - 0.00000000007303 63.0
DTH2_k127_5155623_6 - - - - 0.0000001815 53.0
DTH2_k127_5160134_0 PFAM PfkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 290.0
DTH2_k127_5160134_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000001078 116.0
DTH2_k127_5167407_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
DTH2_k127_5167407_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000002359 157.0
DTH2_k127_5167407_2 mRNA catabolic process - - - 0.0000000000000000000000000009915 120.0
DTH2_k127_5167407_3 - - - - 0.00000000000000000000000006323 114.0
DTH2_k127_5167407_4 Domain of unknown function (DUF3786) - - - 0.0000004144 53.0
DTH2_k127_5177830_0 Sensory domain found in PocR K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002826 266.0
DTH2_k127_5177830_1 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000002352 200.0
DTH2_k127_5177830_2 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000002128 110.0
DTH2_k127_5181129_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
DTH2_k127_5181129_2 COG2267 Lysophospholipase K01048 - 3.1.1.5 0.0001622 48.0
DTH2_k127_5190874_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 432.0
DTH2_k127_5190874_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 320.0
DTH2_k127_5190874_2 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001309 296.0
DTH2_k127_5190874_3 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000487 266.0
DTH2_k127_5190874_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000002133 222.0
DTH2_k127_5190874_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000002702 198.0
DTH2_k127_5190874_7 Outer membrane protein (OmpH-like) - - - 0.0005415 48.0
DTH2_k127_521580_0 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003216 290.0
DTH2_k127_521580_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000001225 94.0
DTH2_k127_5224500_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000634 212.0
DTH2_k127_5224500_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000563 189.0
DTH2_k127_5224500_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000002489 79.0
DTH2_k127_522831_0 radical SAM domain protein K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 477.0
DTH2_k127_522831_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000003892 146.0
DTH2_k127_522831_2 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000002103 119.0
DTH2_k127_5264518_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.745e-210 683.0
DTH2_k127_5264518_1 histidine kinase A domain protein - - - 0.000000000000000000001445 99.0
DTH2_k127_5266208_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 513.0
DTH2_k127_5273124_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 526.0
DTH2_k127_5273124_1 AraC-like ligand binding domain - - - 0.000000000000000000000000000003099 123.0
DTH2_k127_5273124_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000006389 128.0
DTH2_k127_5273124_3 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000000000000002969 122.0
DTH2_k127_5273124_4 Protein of unknown function (DUF1559) - - - 0.0001803 47.0
DTH2_k127_5273124_5 PAS domain K09155 - - 0.0009906 45.0
DTH2_k127_5273973_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 330.0
DTH2_k127_5273973_1 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 319.0
DTH2_k127_5273973_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000004811 151.0
DTH2_k127_5298876_0 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 435.0
DTH2_k127_5298876_1 Oxidoreductase NAD-binding domain K00528,K02823,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
DTH2_k127_5298876_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
DTH2_k127_5298876_3 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
DTH2_k127_5298876_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000006021 218.0
DTH2_k127_5298876_5 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000005035 182.0
DTH2_k127_5303149_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.064e-208 656.0
DTH2_k127_5303149_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.798e-197 625.0
DTH2_k127_5303149_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000009616 55.0
DTH2_k127_5303149_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0003627 47.0
DTH2_k127_5303149_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000005545 189.0
DTH2_k127_5303149_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000002703 145.0
DTH2_k127_5303149_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000376 131.0
DTH2_k127_5303149_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000001372 96.0
DTH2_k127_5303149_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000005609 80.0
DTH2_k127_5303149_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000004846 75.0
DTH2_k127_5303149_9 PQQ enzyme repeat - - - 0.0000000183 66.0
DTH2_k127_531665_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 545.0
DTH2_k127_531665_1 FHA domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000005508 259.0
DTH2_k127_531665_2 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000004755 156.0
DTH2_k127_531665_3 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.000000000000000000008752 96.0
DTH2_k127_531665_4 - - - - 0.0000001532 61.0
DTH2_k127_531665_5 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - 0.0002005 53.0
DTH2_k127_5321924_0 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 596.0
DTH2_k127_5321924_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 533.0
DTH2_k127_5321924_2 Alcohol dehydrogenase GroES-like domain K19956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 499.0
DTH2_k127_5321924_3 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 490.0
DTH2_k127_5321924_4 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 381.0
DTH2_k127_5321924_5 PFAM Short-chain dehydrogenase reductase SDR K00068 - 1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
DTH2_k127_5321924_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001142 281.0
DTH2_k127_5321924_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000006931 246.0
DTH2_k127_5321924_8 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
DTH2_k127_5321924_9 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000005699 178.0
DTH2_k127_5323360_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 410.0
DTH2_k127_5323360_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000005918 146.0
DTH2_k127_5323360_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0002281 47.0
DTH2_k127_532464_0 Peptidase, M56 K02172 - - 0.0000000000000000000000000000000003757 151.0
DTH2_k127_532464_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000005133 104.0
DTH2_k127_532464_2 Psort location CytoplasmicMembrane, score K02172 - - 0.000000000000001736 91.0
DTH2_k127_5397189_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 522.0
DTH2_k127_5397189_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 333.0
DTH2_k127_5397189_2 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000001916 108.0
DTH2_k127_5421121_0 UPF0210 protein K09157 - - 0.00000000000000000000000000000000000000000000002326 177.0
DTH2_k127_5421121_2 ACT domain protein K07166 - - 0.0000000000000000005736 89.0
DTH2_k127_5425253_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 284.0
DTH2_k127_5425253_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002055 257.0
DTH2_k127_5425253_2 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000005244 256.0
DTH2_k127_5425253_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.0000000000000001254 92.0
DTH2_k127_5463389_0 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.00000000000000000000000000000007278 130.0
DTH2_k127_5463389_1 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 0.00000000000000000000000005867 109.0
DTH2_k127_5463389_2 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K04749 - - 0.000000000000000000002336 97.0
DTH2_k127_5463389_3 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000006552 96.0
DTH2_k127_5463389_4 Transcriptional regulator - - - 0.0000000000000002087 84.0
DTH2_k127_5463389_5 Protein of unknown function (DUF2442) - - - 0.000000000000001234 78.0
DTH2_k127_5478886_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.374e-219 696.0
DTH2_k127_5478886_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 521.0
DTH2_k127_5478886_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004001 237.0
DTH2_k127_5478886_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000128 152.0
DTH2_k127_5478886_4 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000006051 123.0
DTH2_k127_5478886_5 belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000007323 123.0
DTH2_k127_5485233_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.00000000000000000000000000000000000000000000003274 176.0
DTH2_k127_5485233_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000002461 153.0
DTH2_k127_5485233_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000004606 86.0
DTH2_k127_55607_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 306.0
DTH2_k127_55607_1 glycosyl transferase - - - 0.00000000000000000000000000000000000005303 161.0
DTH2_k127_55607_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000003658 146.0
DTH2_k127_55607_3 - - - - 0.0000000226 61.0
DTH2_k127_5587225_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 623.0
DTH2_k127_5587225_1 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 468.0
DTH2_k127_5587225_2 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 307.0
DTH2_k127_5587225_3 Lipopolysaccharide-assembly - - - 0.0000000000000000000001988 104.0
DTH2_k127_5587225_4 Tetratricopeptide TPR_2 repeat protein K05807 - - 0.00000000000007119 83.0
DTH2_k127_5604505_0 In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS K03150 - 4.1.99.19 2.174e-196 619.0
DTH2_k127_5604505_1 Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 386.0
DTH2_k127_5604505_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 371.0
DTH2_k127_5604505_3 PDZ domain (Also known as DHR K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002051 273.0
DTH2_k127_5621173_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 261.0
DTH2_k127_5621173_1 Transposase and inactivated derivatives - - - 0.00000000001398 65.0
DTH2_k127_5625492_0 formate acetyltransferase K00656 - 2.3.1.54 0.0 1057.0
DTH2_k127_5625492_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.344e-269 850.0
DTH2_k127_5625492_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 281.0
DTH2_k127_5625492_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002151 262.0
DTH2_k127_5625492_4 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 254.0
DTH2_k127_5625492_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000004881 221.0
DTH2_k127_5625492_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000002192 179.0
DTH2_k127_5625492_7 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000149 72.0
DTH2_k127_5646950_0 - - - - 0.000000000000000000000000000000000000000000002591 181.0
DTH2_k127_5646950_1 SEC-C Motif Domain Protein - - - 0.000000000000000000000000000000000000002894 163.0
DTH2_k127_5646950_2 Sigma-70, region 4 - - - 0.0000000000000003658 85.0
DTH2_k127_5654658_0 membrane GTPase involved in stress response K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 614.0
DTH2_k127_5654658_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 353.0
DTH2_k127_5654658_2 rna polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 348.0
DTH2_k127_5654658_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
DTH2_k127_5654658_4 N-acetylmuramoyl-L-alanine amidase - - - 0.000000002796 64.0
DTH2_k127_5654658_5 COG NOG33517 non supervised orthologous group - - - 0.000003059 53.0
DTH2_k127_5695821_0 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 443.0
DTH2_k127_5695821_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000133 260.0
DTH2_k127_5695821_2 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
DTH2_k127_5697665_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.767e-255 793.0
DTH2_k127_5697665_1 glucuronate isomerase K01812 - 5.3.1.12 1.498e-199 628.0
DTH2_k127_5697665_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 385.0
DTH2_k127_5697665_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 364.0
DTH2_k127_5697665_4 glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000001044 89.0
DTH2_k127_5697665_5 pfkB family carbohydrate kinase - - - 0.000000000001798 71.0
DTH2_k127_5720697_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 408.0
DTH2_k127_5720697_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004889 264.0
DTH2_k127_5720697_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000001986 78.0
DTH2_k127_5727526_0 Alcohol dehydrogenase GroES domain protein K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 460.0
DTH2_k127_5727526_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
DTH2_k127_5727526_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000697 230.0
DTH2_k127_5727526_3 oligosaccharyl transferase activity - - - 0.0000000002566 74.0
DTH2_k127_5734468_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
DTH2_k127_5734468_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 329.0
DTH2_k127_5734468_2 Phage portal protein, SPP1 Gp6-like - - - 0.0000009421 61.0
DTH2_k127_5746552_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 306.0
DTH2_k127_5746552_1 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000003334 234.0
DTH2_k127_5746552_2 OmpA family - - - 0.0000000000000000000003236 105.0
DTH2_k127_5746552_3 competence protein ComEC Rec2 K02238 - - 0.0000000000000000002644 95.0
DTH2_k127_5763399_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 399.0
DTH2_k127_5763399_1 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 369.0
DTH2_k127_5763399_2 symporter activity K03307 - - 0.00000000000000000000000465 108.0
DTH2_k127_5766381_0 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004888 253.0
DTH2_k127_5766381_1 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000002645 214.0
DTH2_k127_5766381_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002128 209.0
DTH2_k127_5766381_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000003051 211.0
DTH2_k127_5766381_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000005076 178.0
DTH2_k127_5784385_0 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 446.0
DTH2_k127_5806545_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 549.0
DTH2_k127_5806545_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000007896 51.0
DTH2_k127_5816649_0 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 550.0
DTH2_k127_5816649_1 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 314.0
DTH2_k127_5816649_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000000000000000000000000000009139 166.0
DTH2_k127_5816649_3 - K01992 - - 0.000000000000000000005377 107.0
DTH2_k127_5816649_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000006587 103.0
DTH2_k127_5816649_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000001015 76.0
DTH2_k127_5829864_0 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 313.0
DTH2_k127_5829864_1 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000004226 214.0
DTH2_k127_5829864_2 NfeD-like C-terminal, partner-binding - - - 0.00000000000000001793 89.0
DTH2_k127_5829864_4 COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes - - - 0.000007195 53.0
DTH2_k127_5829864_5 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0003154 51.0
DTH2_k127_5862976_0 chitin binding K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000002848 238.0
DTH2_k127_5862976_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000003735 166.0
DTH2_k127_5862976_2 PFAM TfoX N-terminal domain K07343 - - 0.000000000000000000000000001247 117.0
DTH2_k127_5862976_3 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000009392 100.0
DTH2_k127_5880716_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 615.0
DTH2_k127_5880716_1 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 552.0
DTH2_k127_5880716_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 314.0
DTH2_k127_5880716_3 ROK family - - - 0.0000000000000000000000000000000000000000000000006397 190.0
DTH2_k127_5880716_4 - - - - 0.0000000000000000000000000000000000000000249 157.0
DTH2_k127_5880716_5 Domain of unknown function (DUF2088) - - - 0.0000000001249 63.0
DTH2_k127_5893240_0 translation initiation factor activity K01448,K07315,K12308,K21000,K21470 - 3.1.3.3,3.2.1.23,3.5.1.28 0.00000000000000000000002096 115.0
DTH2_k127_5917704_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5e-218 690.0
DTH2_k127_5917704_1 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 492.0
DTH2_k127_5917704_2 Type II secretory pathway component PulF K02653 - - 0.000000000000000000000000000000000000000000000000000007962 198.0
DTH2_k127_5917704_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000007075 81.0
DTH2_k127_594760_0 PFAM Radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 344.0
DTH2_k127_594760_1 KilA-N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001435 274.0
DTH2_k127_594760_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000001922 235.0
DTH2_k127_594760_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000001929 228.0
DTH2_k127_594760_4 flagellar biosynthetic protein FliR K02421 - - 0.00000000000000002498 93.0
DTH2_k127_594760_5 Role in flagellar biosynthesis K02420 - - 0.0000000000000005864 80.0
DTH2_k127_594760_6 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000006567 81.0
DTH2_k127_594760_7 flagellar K02418 - - 0.000002556 55.0
DTH2_k127_59503_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 558.0
DTH2_k127_5958061_0 COG1448 Aspartate tyrosine aromatic aminotransferase K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 496.0
DTH2_k127_5958061_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 475.0
DTH2_k127_5958061_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 368.0
DTH2_k127_5958061_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000002747 239.0
DTH2_k127_5958061_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004797 196.0
DTH2_k127_5958061_5 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000006287 160.0
DTH2_k127_5958061_6 PFAM O-Antigen - - - 0.00000000000000000008005 105.0
DTH2_k127_5969340_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001949 282.0
DTH2_k127_5969340_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001627 243.0
DTH2_k127_5969340_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000007293 223.0
DTH2_k127_5969340_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000003409 180.0
DTH2_k127_5969340_4 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000633 138.0
DTH2_k127_5969340_5 Protein of unknown function (DUF4056) - - - 0.0000000000000000000002992 109.0
DTH2_k127_5969340_6 - K07164,K22391 - 3.5.4.16 0.000000000000000000002689 104.0
DTH2_k127_5969340_7 PFAM PEGA domain - - - 0.000000000000000001553 91.0
DTH2_k127_5969340_8 Mediates influx of magnesium ions K03284 - - 0.000000000001365 70.0
DTH2_k127_5984469_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
DTH2_k127_5984469_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000001958 190.0
DTH2_k127_5984469_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000009917 141.0
DTH2_k127_5984469_3 Glycosyl transferase 4-like - - - 0.000000000002672 78.0
DTH2_k127_5984469_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000002525 68.0
DTH2_k127_5984469_5 PFAM UvrB UvrC protein K19411 - - 0.000000007509 60.0
DTH2_k127_5989186_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 364.0
DTH2_k127_5989186_1 KTSC domain - - - 0.0000000000000000000000000000000002355 132.0
DTH2_k127_5989186_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000002489 129.0
DTH2_k127_5990043_0 neurotransmitter:sodium symporter activity K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 511.0
DTH2_k127_5990043_1 Sodium:dicarboxylate symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 459.0
DTH2_k127_5990043_2 aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 398.0
DTH2_k127_5990043_3 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
DTH2_k127_5990043_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
DTH2_k127_5990043_5 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 232.0
DTH2_k127_5990043_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001213 238.0
DTH2_k127_5990043_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000002876 167.0
DTH2_k127_5990043_8 TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000002173 171.0
DTH2_k127_6024029_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 6.311e-202 645.0
DTH2_k127_6024029_1 Domain of unknown function (DUF4954) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 477.0
DTH2_k127_6024029_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 317.0
DTH2_k127_6024029_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 302.0
DTH2_k127_6024029_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002189 273.0
DTH2_k127_6024029_5 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000003991 220.0
DTH2_k127_6024029_6 Belongs to the SUA5 family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000003917 203.0
DTH2_k127_6024029_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000857 148.0
DTH2_k127_6024029_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000003127 96.0
DTH2_k127_6043390_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.764e-254 797.0
DTH2_k127_6043390_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.438e-218 692.0
DTH2_k127_6043390_10 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000001083 229.0
DTH2_k127_6043390_11 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
DTH2_k127_6043390_12 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000005084 197.0
DTH2_k127_6043390_13 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000004846 156.0
DTH2_k127_6043390_14 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000257 135.0
DTH2_k127_6043390_2 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 4.25e-216 685.0
DTH2_k127_6043390_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 505.0
DTH2_k127_6043390_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 468.0
DTH2_k127_6043390_5 PFAM AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 457.0
DTH2_k127_6043390_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 333.0
DTH2_k127_6043390_7 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 286.0
DTH2_k127_6043390_8 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009831 253.0
DTH2_k127_6043390_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000006728 241.0
DTH2_k127_6095711_0 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 477.0
DTH2_k127_6095711_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000003906 229.0
DTH2_k127_6095711_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000001249 169.0
DTH2_k127_6095711_3 - - - - 0.0000002105 62.0
DTH2_k127_6135691_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000002307 235.0
DTH2_k127_6135691_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000004008 185.0
DTH2_k127_6135691_2 PFAM Glycoside hydrolase, clan GH-D - - - 0.000000000000000000000000000000004983 148.0
DTH2_k127_6173171_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.166e-208 666.0
DTH2_k127_6173171_1 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 606.0
DTH2_k127_6173171_10 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000005562 152.0
DTH2_k127_6173171_11 - - - - 0.00000000000000000000000000000000008795 144.0
DTH2_k127_6173171_12 PFAM RNA recognition motif - - - 0.00000000000000000000000008977 111.0
DTH2_k127_6173171_13 - - - - 0.0000000007154 62.0
DTH2_k127_6173171_2 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 534.0
DTH2_k127_6173171_3 transcription initiation from RNA polymerase III promoter K03022 GO:0000228,GO:0000428,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005666,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006352,GO:0006383,GO:0006384,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009304,GO:0009987,GO:0010467,GO:0015630,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042797,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 505.0
DTH2_k127_6173171_4 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 498.0
DTH2_k127_6173171_5 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 494.0
DTH2_k127_6173171_6 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 492.0
DTH2_k127_6173171_7 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000003835 165.0
DTH2_k127_6173171_8 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000637 162.0
DTH2_k127_6173171_9 single-species biofilm formation - - - 0.0000000000000000000000000000000000000000007562 161.0
DTH2_k127_6184068_0 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 503.0
DTH2_k127_6184068_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000004917 241.0
DTH2_k127_6184068_2 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000001359 138.0
DTH2_k127_6184068_3 Major Facilitator Superfamily K08177 - - 0.000000000000003714 80.0
DTH2_k127_6222193_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 378.0
DTH2_k127_6222193_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 334.0
DTH2_k127_6222193_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
DTH2_k127_6222193_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
DTH2_k127_6222193_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000002966 226.0
DTH2_k127_6222193_5 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000223 144.0
DTH2_k127_6222193_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000001549 100.0
DTH2_k127_6223325_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 445.0
DTH2_k127_6223325_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000001862 140.0
DTH2_k127_6233839_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002009 258.0
DTH2_k127_6233839_1 Flagellar L-ring protein K02393 - - 0.0000000000000001258 84.0
DTH2_k127_6233839_2 Rod binding protein K02395 - - 0.00014 49.0
DTH2_k127_6244408_0 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 560.0
DTH2_k127_6244408_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 484.0
DTH2_k127_6244408_2 - - - - 0.000000000008705 73.0
DTH2_k127_6244408_3 - - - - 0.00000003547 66.0
DTH2_k127_6248857_0 Evidence 4 Homologs of previously reported genes of K06990 - - 0.0000000000000000000000000000000000000000000000000000000001027 213.0
DTH2_k127_6248857_1 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000002548 182.0
DTH2_k127_6248857_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000002476 146.0
DTH2_k127_6248857_4 positive regulation of growth - - - 0.00000000263 61.0
DTH2_k127_6299742_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 428.0
DTH2_k127_6339212_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 462.0
DTH2_k127_6339212_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 352.0
DTH2_k127_6339212_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 349.0
DTH2_k127_6339212_3 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
DTH2_k127_6339212_4 PFAM Rhomboid family - - - 0.0000000000000000000000000000001968 136.0
DTH2_k127_6340736_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.083e-204 654.0
DTH2_k127_6340736_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000004889 187.0
DTH2_k127_6340736_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000003039 121.0
DTH2_k127_6340736_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000683 81.0
DTH2_k127_6340736_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000351 68.0
DTH2_k127_634276_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 370.0
DTH2_k127_634276_1 NAD binding K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 330.0
DTH2_k127_634276_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001171 214.0
DTH2_k127_6351805_0 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 407.0
DTH2_k127_6351805_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
DTH2_k127_6351805_2 stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000006015 198.0
DTH2_k127_6351805_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000007399 189.0
DTH2_k127_6351805_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000002071 176.0
DTH2_k127_6351805_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598 - 4.1.1.36 0.000000000000000000000000000000000000000004337 161.0
DTH2_k127_6351805_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000005512 71.0
DTH2_k127_6351805_7 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000002489 58.0
DTH2_k127_6372678_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 407.0
DTH2_k127_6372678_1 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 357.0
DTH2_k127_6372678_10 Staphylococcal nuclease homologue - - - 0.000000002694 66.0
DTH2_k127_6372678_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0016783,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000002306 63.0
DTH2_k127_6372678_12 competence protein COMEC K02238 - - 0.00001179 55.0
DTH2_k127_6372678_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
DTH2_k127_6372678_3 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005751 249.0
DTH2_k127_6372678_4 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 244.0
DTH2_k127_6372678_5 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000001244 235.0
DTH2_k127_6372678_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000001183 221.0
DTH2_k127_6372678_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000003164 198.0
DTH2_k127_6372678_8 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000000000000000522 165.0
DTH2_k127_6372678_9 - - - - 0.00000000000000000000000000000007476 129.0
DTH2_k127_639724_0 PFAM Glycosyl hydrolases family 38 C-terminal domain - - - 3.196e-283 892.0
DTH2_k127_639724_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 474.0
DTH2_k127_639724_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 471.0
DTH2_k127_639724_3 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 432.0
DTH2_k127_639724_4 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 395.0
DTH2_k127_639724_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000001699 180.0
DTH2_k127_639724_6 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000002927 156.0
DTH2_k127_639724_7 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000228 68.0
DTH2_k127_6413726_0 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 326.0
DTH2_k127_6413726_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000009551 220.0
DTH2_k127_6413726_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000001481 207.0
DTH2_k127_6413726_3 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000001315 163.0
DTH2_k127_6417167_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.231e-242 766.0
DTH2_k127_6417167_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 363.0
DTH2_k127_6417167_2 TIGRFAM mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002016 262.0
DTH2_k127_6417167_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000002473 228.0
DTH2_k127_6417167_4 endonuclease III - - - 0.000000000000000000000000000000000000000000009702 165.0
DTH2_k127_6417167_5 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000312 127.0
DTH2_k127_6417167_6 CAAX protease self-immunity - - - 0.00000000000000000000000000103 125.0
DTH2_k127_6417167_7 Protein of unknown function DUF2617 - - - 0.000000000000000000003819 100.0
DTH2_k127_6417167_8 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000004773 76.0
DTH2_k127_6433639_0 PAS fold K02030 - - 0.00000000000000000000000000000000000000000000000000004854 215.0
DTH2_k127_6433639_1 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000002603 141.0
DTH2_k127_6455009_0 Sulfatase K01130 - 3.1.6.1 0.0 1310.0
DTH2_k127_6455009_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 380.0
DTH2_k127_6455009_2 - - - - 0.00000000000000000000001622 106.0
DTH2_k127_6455009_3 Protein of unknown function (DUF3313) - - - 0.00000003734 62.0
DTH2_k127_6480985_0 Hypothetical glycosyl hydrolase 6 - - - 6.478e-252 794.0
DTH2_k127_6481739_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 8.23e-220 704.0
DTH2_k127_6516381_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.906e-200 635.0
DTH2_k127_6516381_1 SMART chemotaxis sensory transducer K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 584.0
DTH2_k127_6516381_10 - - - - 0.0000006516 51.0
DTH2_k127_6516381_11 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.000001784 58.0
DTH2_k127_6516381_12 Major Facilitator Superfamily - - - 0.000002312 59.0
DTH2_k127_6516381_2 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 425.0
DTH2_k127_6516381_3 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 366.0
DTH2_k127_6516381_4 ABC transporter K02013,K05776 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000003881 246.0
DTH2_k127_6516381_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
DTH2_k127_6516381_6 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
DTH2_k127_6516381_7 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000005006 196.0
DTH2_k127_6516381_8 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000001592 132.0
DTH2_k127_6516381_9 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000009202 124.0
DTH2_k127_6520263_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 384.0
DTH2_k127_6520263_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 389.0
DTH2_k127_6520263_10 - - - - 0.000000000009296 70.0
DTH2_k127_6520263_11 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0002017 51.0
DTH2_k127_6520263_2 Hydrolyase tartrate alpha subunit fumarate domain protein Fe-S type K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
DTH2_k127_6520263_3 PFAM GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000001302 249.0
DTH2_k127_6520263_4 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000003929 198.0
DTH2_k127_6520263_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000006324 180.0
DTH2_k127_6520263_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000001008 153.0
DTH2_k127_6520263_7 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000001335 128.0
DTH2_k127_6520263_8 - - - - 0.000000000000000000000000001735 112.0
DTH2_k127_6520263_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000002108 113.0
DTH2_k127_6523775_1 PFAM Methyltransferase - - - 0.0001564 51.0
DTH2_k127_6533996_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 517.0
DTH2_k127_6533996_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 299.0
DTH2_k127_6533996_2 FR47-like protein K03826,K22477 - 2.3.1.1 0.0000001375 53.0
DTH2_k127_6571780_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1017.0
DTH2_k127_6571780_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 437.0
DTH2_k127_657598_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 592.0
DTH2_k127_657598_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 505.0
DTH2_k127_657598_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 351.0
DTH2_k127_657598_3 - - - - 0.0000000000000000000000000000000000000000000000003713 186.0
DTH2_k127_657598_4 Domain of unknown function (DUF4136) - - - 0.00009995 51.0
DTH2_k127_657598_5 Sulfate permease family K03321 - - 0.0007747 43.0
DTH2_k127_6589432_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 464.0
DTH2_k127_6589432_1 Bax inhibitor 1 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007431 241.0
DTH2_k127_6599050_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 444.0
DTH2_k127_6599050_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000002324 84.0
DTH2_k127_6602393_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 460.0
DTH2_k127_6602393_1 General secretory system II protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 420.0
DTH2_k127_6602393_10 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000008745 57.0
DTH2_k127_6602393_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 403.0
DTH2_k127_6602393_3 Belongs to the purine-cytosine permease (2.A.39) family K10974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 381.0
DTH2_k127_6602393_4 formate dehydrogenase K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 338.0
DTH2_k127_6602393_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004935 272.0
DTH2_k127_6602393_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000002145 251.0
DTH2_k127_6602393_7 - - - - 0.00000000000000000000000000000000000000000000000000000009119 204.0
DTH2_k127_6602393_8 ApbE family - - - 0.000000000000000000000000000000000006048 158.0
DTH2_k127_6602393_9 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000002271 137.0
DTH2_k127_6637734_0 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 469.0
DTH2_k127_6637734_1 Transposase domain (DUF772) K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 454.0
DTH2_k127_6637734_2 Nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007163 278.0
DTH2_k127_6637734_3 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000000000000000000000000000000000000000001764 179.0
DTH2_k127_6637734_4 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000005581 119.0
DTH2_k127_6637734_5 - - - - 0.0001815 45.0
DTH2_k127_6656857_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001009 255.0
DTH2_k127_6656857_1 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000003922 209.0
DTH2_k127_6656857_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000001004 190.0
DTH2_k127_6656857_3 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000001212 179.0
DTH2_k127_6656857_4 - - - - 0.00000000000000000000000000000000000003212 156.0
DTH2_k127_6659792_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 592.0
DTH2_k127_6659792_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 468.0
DTH2_k127_6659792_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
DTH2_k127_6659792_3 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 311.0
DTH2_k127_6659792_4 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 286.0
DTH2_k127_6659792_5 AraC-like ligand binding domain K02854 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008894 262.0
DTH2_k127_6659792_6 Uncharacterized conserved protein (DUF2294) - - - 0.000000000000000000000000000000000000000000000000003951 183.0
DTH2_k127_6659792_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0001291 46.0
DTH2_k127_6693600_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 368.0
DTH2_k127_6693600_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003665 286.0
DTH2_k127_6693600_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
DTH2_k127_6693600_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000306 260.0
DTH2_k127_6693600_4 4-phosphoerythronate dehydrogenase activity K03473 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 0.00000000001398 65.0
DTH2_k127_6705239_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000008402 178.0
DTH2_k127_6705239_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000003594 164.0
DTH2_k127_6705239_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000006465 131.0
DTH2_k127_6705239_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000002938 130.0
DTH2_k127_6747126_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 499.0
DTH2_k127_6747126_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000002147 198.0
DTH2_k127_6747126_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000001233 156.0
DTH2_k127_6747126_3 3D domain - - - 0.000000000000000002954 95.0
DTH2_k127_6747126_4 phosphoserine phosphatase activity - - - 0.000000005262 59.0
DTH2_k127_6750587_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 305.0
DTH2_k127_6750587_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 307.0
DTH2_k127_6750587_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
DTH2_k127_6754754_0 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 308.0
DTH2_k127_6754754_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000004777 144.0
DTH2_k127_6754754_2 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000001964 122.0
DTH2_k127_6754754_3 chitin binding K01183 - 3.2.1.14 0.00004207 51.0
DTH2_k127_6782303_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 296.0
DTH2_k127_6782303_1 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000123 124.0
DTH2_k127_6799576_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 466.0
DTH2_k127_6799576_1 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 332.0
DTH2_k127_6799576_3 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000001151 174.0
DTH2_k127_6799576_4 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000007449 135.0
DTH2_k127_683145_0 Evidence 5 No homology to any previously reported sequences K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 467.0
DTH2_k127_683145_1 - - - - 0.00000000000000000000000000000000000000000000000008536 190.0
DTH2_k127_683145_2 Cold shock protein K03704 - - 0.0000000000000000000002164 97.0
DTH2_k127_683145_3 general secretion pathway protein K02456 - - 0.000000009136 66.0
DTH2_k127_683145_4 - - - - 0.000003332 56.0
DTH2_k127_683145_5 Competence protein - - - 0.0004975 47.0
DTH2_k127_6833441_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 350.0
DTH2_k127_6833441_1 Transposase domain (DUF772) - - - 0.0000000000000000001561 93.0
DTH2_k127_6837225_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 401.0
DTH2_k127_6837225_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 323.0
DTH2_k127_6837225_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001054 218.0
DTH2_k127_6837225_3 Tetratricopeptide repeat protein - - - 0.0006987 53.0
DTH2_k127_6878702_0 Belongs to the GSP D family K02666 - - 0.0000000000000000000000000002764 123.0
DTH2_k127_6878702_1 PFAM Pilus assembly protein PilO K02664 - - 0.00001921 53.0
DTH2_k127_6898692_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 498.0
DTH2_k127_6898692_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000003483 124.0
DTH2_k127_6898692_2 peptidoglycan-binding protein, lysm - - - 0.0000001182 58.0
DTH2_k127_6960043_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000007142 195.0
DTH2_k127_6960043_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000002448 134.0
DTH2_k127_6965942_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 348.0
DTH2_k127_6965942_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005781 258.0
DTH2_k127_6965942_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000007625 51.0
DTH2_k127_696811_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000009739 156.0
DTH2_k127_7000441_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 434.0
DTH2_k127_7059976_0 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007907 277.0
DTH2_k127_7059976_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000002081 127.0
DTH2_k127_7062331_0 hydrogenase large subunit K00533,K06281 - 1.12.7.2,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 542.0
DTH2_k127_7062331_1 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 309.0
DTH2_k127_7062331_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000003691 234.0
DTH2_k127_7062331_3 PFAM chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000007697 218.0
DTH2_k127_7062331_4 Bax inhibitor 1 like - - - 0.000000000000000001631 87.0
DTH2_k127_7073595_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 322.0
DTH2_k127_7073595_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
DTH2_k127_7073595_2 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 306.0
DTH2_k127_7073595_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007381 271.0
DTH2_k127_7073595_4 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000005439 157.0
DTH2_k127_7073595_5 PFAM Transcription termination factor nusG K05785 - - 0.000000000000000000000000000002127 127.0
DTH2_k127_7073595_6 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000009875 87.0
DTH2_k127_7073595_7 - - - - 0.00000000008379 67.0
DTH2_k127_7073595_8 - - - - 0.0008835 45.0
DTH2_k127_7096797_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 395.0
DTH2_k127_7096797_1 PFAM peptidase S1 and S6 chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.000000000406 73.0
DTH2_k127_7098359_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000005066 226.0
DTH2_k127_7098359_1 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000002459 216.0
DTH2_k127_7098359_2 transcriptional regulator K07722 - - 0.00000000000000000000000000000000006528 138.0
DTH2_k127_7098359_3 Cobalt transport protein K02008 - - 0.000000000000000000000000000000001227 139.0
DTH2_k127_7098359_4 Carbohydrate-selective porin K07267 - - 0.0000000000000000000007105 109.0
DTH2_k127_7129253_0 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 360.0
DTH2_k127_7129253_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000883 205.0
DTH2_k127_7129253_2 Protein of unknown function (DUF4056) - - - 0.00000858 54.0
DTH2_k127_717648_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 5.201e-200 648.0
DTH2_k127_717648_1 Glycoside hydrolase, family 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 590.0
DTH2_k127_717648_2 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 359.0
DTH2_k127_717648_3 Ig domain protein group 2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 370.0
DTH2_k127_717648_4 SMART Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005686 294.0
DTH2_k127_717648_5 - K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000593 218.0
DTH2_k127_717648_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000002743 180.0
DTH2_k127_717648_7 Integrase core domain K07497 - - 0.000001232 54.0
DTH2_k127_7205518_0 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 287.0
DTH2_k127_7205518_1 Hydrolase, tatd K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000001132 209.0
DTH2_k127_7205518_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003236 138.0
DTH2_k127_7205518_3 - - - - 0.000000000000000000000000000008132 120.0
DTH2_k127_7205518_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000008116 97.0
DTH2_k127_7205518_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000003791 93.0
DTH2_k127_72306_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 558.0
DTH2_k127_72306_1 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 551.0
DTH2_k127_72306_10 - - - - 0.000000000000000000000008235 107.0
DTH2_k127_72306_11 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000006017 85.0
DTH2_k127_72306_12 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000001293 58.0
DTH2_k127_72306_14 Domain of unknown function (DUF4105) - - - 0.0001951 44.0
DTH2_k127_72306_2 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 422.0
DTH2_k127_72306_3 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005223 291.0
DTH2_k127_72306_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000001072 244.0
DTH2_k127_72306_5 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000002448 236.0
DTH2_k127_72306_6 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000004263 233.0
DTH2_k127_72306_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000003497 198.0
DTH2_k127_72306_8 regulation of circadian rhythm K06919 - - 0.000000000000000000000000000000000000000001599 174.0
DTH2_k127_72306_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000009321 164.0
DTH2_k127_7276809_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 530.0
DTH2_k127_7276809_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 486.0
DTH2_k127_7276809_10 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000005614 74.0
DTH2_k127_7276809_12 - - - - 0.00002191 47.0
DTH2_k127_7276809_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
DTH2_k127_7276809_3 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000004611 168.0
DTH2_k127_7276809_4 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000000000000000000176 151.0
DTH2_k127_7276809_5 Hydrolase - - - 0.000000000000000000000000000000002177 139.0
DTH2_k127_7276809_6 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000002501 134.0
DTH2_k127_7276809_7 PFAM Phosphoribosyltransferase K02242 - - 0.0000000000000000000000000002926 124.0
DTH2_k127_7276809_8 4Fe-4S binding domain - - - 0.000000000000000002733 85.0
DTH2_k127_7276809_9 Pfam:N_methyl_2 - - - 0.000000000002391 71.0
DTH2_k127_7298203_0 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 417.0
DTH2_k127_7298203_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 402.0
DTH2_k127_7298203_2 Integral membrane protein (PIN domain superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 332.0
DTH2_k127_7298203_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 301.0
DTH2_k127_7298203_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000006157 173.0
DTH2_k127_7298203_5 Histidine kinase - - - 0.0000000000000000000000000000000000003253 156.0
DTH2_k127_7298203_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000006041 131.0
DTH2_k127_7298203_7 - - - - 0.00000000002416 67.0
DTH2_k127_7308648_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 497.0
DTH2_k127_7308648_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 416.0
DTH2_k127_7308648_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 277.0
DTH2_k127_7308648_3 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000007312 209.0
DTH2_k127_7308648_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000006914 177.0
DTH2_k127_7308648_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000008388 156.0
DTH2_k127_7308648_6 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000003234 83.0
DTH2_k127_7308648_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0009656 49.0
DTH2_k127_7341910_0 COG4992 Ornithine acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 495.0
DTH2_k127_7341910_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 331.0
DTH2_k127_7341910_2 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 340.0
DTH2_k127_7341910_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
DTH2_k127_7341910_4 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000228 185.0
DTH2_k127_7341910_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000007023 139.0
DTH2_k127_7341910_6 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000001903 134.0
DTH2_k127_7341910_7 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000003905 99.0
DTH2_k127_7341910_8 Cytochrome c - - - 0.0000000000000004129 89.0
DTH2_k127_7404306_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000006148 169.0
DTH2_k127_7404306_1 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000005882 150.0
DTH2_k127_7441902_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 434.0
DTH2_k127_7441902_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000005417 271.0
DTH2_k127_7441902_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000001946 172.0
DTH2_k127_7441902_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.0000000000000000000000000000001179 130.0
DTH2_k127_7462891_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1273.0
DTH2_k127_7462891_1 - - - - 0.00001569 47.0
DTH2_k127_7499865_0 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 429.0
DTH2_k127_7499865_1 Bacterial regulatory protein, arsR - - - 0.000000000000000000002377 97.0
DTH2_k127_7550447_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 553.0
DTH2_k127_7550447_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000001803 144.0
DTH2_k127_7550447_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000003014 128.0
DTH2_k127_7550447_3 Bacterial regulatory proteins, tetR family - - - 0.0000000001048 70.0
DTH2_k127_7604220_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 8.25e-222 701.0
DTH2_k127_7604220_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.547e-203 646.0
DTH2_k127_7604220_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 382.0
DTH2_k127_7604220_3 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
DTH2_k127_7604220_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000003426 258.0
DTH2_k127_7604220_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000009019 216.0
DTH2_k127_7604220_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000001938 131.0
DTH2_k127_7604220_7 Regulatory protein, FmdB family - - - 0.00000000000000000000000000007593 119.0
DTH2_k127_7604220_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000003023 116.0
DTH2_k127_7604220_9 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 0.000000002561 58.0
DTH2_k127_762127_0 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 329.0
DTH2_k127_762127_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000415 216.0
DTH2_k127_762127_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000006376 71.0
DTH2_k127_7689357_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 599.0
DTH2_k127_7689357_1 Phosphoglycerate kinase K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 466.0
DTH2_k127_7689357_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 315.0
DTH2_k127_7689357_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000007695 217.0
DTH2_k127_7732500_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
DTH2_k127_7732500_1 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000008081 241.0
DTH2_k127_7732500_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000003534 64.0
DTH2_k127_7732500_3 phosphate ion binding K02040 - - 0.0000001373 56.0
DTH2_k127_778129_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 505.0
DTH2_k127_778129_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
DTH2_k127_778129_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
DTH2_k127_778129_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000001068 195.0
DTH2_k127_778129_4 response regulator receiver - - - 0.000000000000000000000000000000000000000000003148 170.0
DTH2_k127_7792697_0 PFAM MltA domain protein K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 471.0
DTH2_k127_7792697_1 Divalent cation transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004335 253.0
DTH2_k127_7792697_2 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000001669 158.0
DTH2_k127_7792697_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000001156 124.0
DTH2_k127_7792697_4 Beta-Casp domain K07576 - - 0.00000000003128 64.0
DTH2_k127_7792697_5 low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000003771 58.0
DTH2_k127_7884006_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 593.0
DTH2_k127_7884006_1 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 412.0
DTH2_k127_7884006_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
DTH2_k127_7884006_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 308.0
DTH2_k127_7884006_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000001124 226.0
DTH2_k127_7884006_5 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000001931 214.0
DTH2_k127_7884006_6 zinc ion binding K06204 - - 0.00000000000000000000002128 108.0
DTH2_k127_7884006_7 PFAM Copper amine oxidase N-terminal domain K01448 - 3.5.1.28 0.00000000000000000000008514 103.0
DTH2_k127_7884006_8 SpoIIAA-like - - - 0.000000000000001143 81.0
DTH2_k127_7884006_9 PFAM Glycosyl transferase, group 1 - - - 0.0000000000007618 75.0
DTH2_k127_7998526_0 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 388.0
DTH2_k127_7998526_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
DTH2_k127_7998526_2 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005498 274.0
DTH2_k127_7998526_3 - - - - 0.0000000000000000000000000000000000000000000000000002637 191.0
DTH2_k127_7998526_4 AraC-like ligand binding domain - - - 0.0009325 46.0
DTH2_k127_801300_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
DTH2_k127_801300_1 Transposase (IS116 IS110 IS902 family) - - - 0.000000000121 73.0
DTH2_k127_8013709_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 305.0
DTH2_k127_8013709_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003993 278.0
DTH2_k127_8013709_2 Belongs to the SpoVG family K06412 - - 0.00000000000000000000000000000000000000000000000000006031 189.0
DTH2_k127_8013709_3 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000000000000000000000000000000000000000000000000003799 191.0
DTH2_k127_8013709_4 AMMECR1 - - - 0.00000000000000000000000000000000000000000000000001826 186.0
DTH2_k127_8013709_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000005077 186.0
DTH2_k127_8013709_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000001433 99.0
DTH2_k127_8019636_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 567.0
DTH2_k127_8019636_1 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 467.0
DTH2_k127_8019636_2 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0000000000000000000000000009785 116.0
DTH2_k127_808063_0 ABC transporter C-terminal domain K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 431.0
DTH2_k127_808063_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000003234 126.0
DTH2_k127_808063_2 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000006257 123.0
DTH2_k127_808063_3 Protein of unknown function DUF86 - - - 0.000000000000000000000000001361 115.0
DTH2_k127_8084612_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 359.0
DTH2_k127_8084612_1 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000000003968 208.0
DTH2_k127_8084612_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000006766 211.0
DTH2_k127_8084612_4 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000003408 152.0
DTH2_k127_8084612_5 membrane - - - 0.0000000000000000000000000000000212 131.0
DTH2_k127_8084612_6 Endonuclease I - - - 0.000046 54.0
DTH2_k127_8088084_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 523.0
DTH2_k127_8088084_1 Oxidoreductase FAD-binding domain K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 373.0
DTH2_k127_8088084_10 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000001782 99.0
DTH2_k127_8088084_11 PFAM FMN-binding domain K00348 - 1.6.5.8 0.000000000000000000003543 102.0
DTH2_k127_8088084_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000001632 83.0
DTH2_k127_8088084_13 Permease, YjgP YjgQ family K11720 - - 0.000005767 57.0
DTH2_k127_8088084_2 Rnf-Nqr subunit, membrane protein K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000001649 242.0
DTH2_k127_8088084_3 Belongs to the NqrDE RnfAE family K00349 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000004577 229.0
DTH2_k127_8088084_4 NQR2, RnfD, RnfE family K00347 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000006735 232.0
DTH2_k127_8088084_5 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000008389 212.0
DTH2_k127_8088084_6 Protein of unknown function (DUF2959) - - - 0.0000000000000000000000000000000000000000000000000000001249 201.0
DTH2_k127_8088084_7 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000002686 194.0
DTH2_k127_8088084_8 Rubrerythrin - - - 0.00000000000000000000000000000000005659 139.0
DTH2_k127_8088084_9 - - - - 0.000000000000000000000000000004133 124.0
DTH2_k127_8096338_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 517.0
DTH2_k127_8096338_1 peptidyl-tyrosine sulfation - - - 0.000001255 55.0
DTH2_k127_809773_0 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
DTH2_k127_809773_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 281.0
DTH2_k127_809773_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000009875 212.0
DTH2_k127_8143183_0 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 510.0
DTH2_k127_8143183_1 symporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 482.0
DTH2_k127_8143183_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 455.0
DTH2_k127_8143183_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 411.0
DTH2_k127_8143183_4 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000000000000000000000000000007573 149.0
DTH2_k127_8143183_5 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000008376 131.0
DTH2_k127_8162213_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 3.7e-202 638.0
DTH2_k127_8162213_1 helix_turn _helix lactose operon repressor K02529,K03435 - - 0.0000000000000000000003352 109.0
DTH2_k127_8162213_2 Domain of unknown function (DUF4832) - - - 0.000000000000000006155 98.0
DTH2_k127_8162213_3 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00002103 56.0
DTH2_k127_8169037_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000427 180.0
DTH2_k127_8173468_0 asparagine synthase K01953 - 6.3.5.4 3.962e-216 687.0
DTH2_k127_8173468_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 522.0
DTH2_k127_8173468_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 362.0
DTH2_k127_8262915_0 ADP-glyceromanno-heptose 6-epimerase activity K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 438.0
DTH2_k127_8262915_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006464 230.0
DTH2_k127_8262915_2 nucleotidyltransferase activity - - - 0.00000000000000000002849 91.0
DTH2_k127_8348487_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 605.0
DTH2_k127_8348487_1 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 422.0
DTH2_k127_8348487_10 Transcriptional regulator with PAS PAC sensors, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000001412 225.0
DTH2_k127_8348487_11 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000009429 214.0
DTH2_k127_8348487_12 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.000000000000000000000000000000000000000000000000000001252 220.0
DTH2_k127_8348487_13 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000004625 192.0
DTH2_k127_8348487_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009272 150.0
DTH2_k127_8348487_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000004699 143.0
DTH2_k127_8348487_16 Bacterial PH domain - - - 0.0000000000002708 79.0
DTH2_k127_8348487_17 ADP-ribosylglycohydrolase - - - 0.000001031 63.0
DTH2_k127_8348487_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 417.0
DTH2_k127_8348487_3 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 437.0
DTH2_k127_8348487_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 372.0
DTH2_k127_8348487_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 343.0
DTH2_k127_8348487_6 ABC-type (unclassified) transport system ATPase K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
DTH2_k127_8348487_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 293.0
DTH2_k127_8348487_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000003259 237.0
DTH2_k127_8348487_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000001054 248.0
DTH2_k127_8382695_0 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005005 257.0
DTH2_k127_8382695_1 - - - - 0.0000000000000000000000000000000000000000000059 172.0
DTH2_k127_8382695_2 Belongs to the Fur family K03711 - - 0.0000000000001501 78.0
DTH2_k127_8382695_3 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000003773 78.0
DTH2_k127_8382695_4 PFAM OmpA MotB domain protein K02557 - - 0.0000000000127 74.0
DTH2_k127_8382695_5 DNA packaging K06909 - - 0.0000003346 63.0
DTH2_k127_8405720_0 L-arabinose isomerase K01804 - 5.3.1.4 8.502e-228 714.0
DTH2_k127_8405720_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 346.0
DTH2_k127_8405720_2 Class II Aldolase and Adducin N-terminal domain K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 296.0
DTH2_k127_8405720_3 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 0.000000000004156 70.0
DTH2_k127_8405720_4 Belongs to the 'phage' integrase family - - - 0.000000156 60.0
DTH2_k127_8405720_5 hydrolase K01048 - 3.1.1.5 0.0001273 45.0
DTH2_k127_8455792_0 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000007837 218.0
DTH2_k127_8455792_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000008797 184.0
DTH2_k127_8455792_2 - - - - 0.000003151 52.0
DTH2_k127_848250_0 Flagellar M-ring protein C-terminal - - - 0.00000000000000000000000000000000000000000000000000002115 207.0
DTH2_k127_848250_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000003305 162.0
DTH2_k127_848250_2 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000002509 132.0
DTH2_k127_848250_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000008736 120.0
DTH2_k127_848250_5 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000003885 64.0
DTH2_k127_848250_6 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000435 66.0
DTH2_k127_8501445_0 PFAM Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1242.0
DTH2_k127_8501445_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 3.185e-203 642.0
DTH2_k127_8537522_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 317.0
DTH2_k127_8537522_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000004216 199.0
DTH2_k127_8537522_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000002884 63.0
DTH2_k127_8541419_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 403.0
DTH2_k127_8541419_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003771 275.0
DTH2_k127_8541419_2 Belongs to the NqrDE RnfAE family K03613 - - 0.0000000000000000000000000000000000000000000000000001261 192.0
DTH2_k127_8541419_3 Peptidase M56 - - - 0.000000000000000000001018 108.0
DTH2_k127_8541419_4 Part of a membrane complex involved in electron transport K03612 - - 0.00001787 54.0
DTH2_k127_8560430_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1660.0
DTH2_k127_8560430_1 COG1283 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000000000000000000000001716 205.0
DTH2_k127_8560430_2 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000001561 205.0
DTH2_k127_8560430_3 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000000000000000000000000000000000000001251 182.0
DTH2_k127_8560430_4 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000004219 147.0
DTH2_k127_8560430_5 TPR Domain containing protein K12600 - - 0.00000000000000000000662 110.0
DTH2_k127_8560430_6 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000005162 76.0
DTH2_k127_8560430_7 Male sterility protein K01710,K08678 - 4.1.1.35,4.2.1.46 0.0004828 44.0
DTH2_k127_8595764_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 449.0
DTH2_k127_8595764_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001432 286.0
DTH2_k127_8645990_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 491.0
DTH2_k127_8645990_1 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.0000008285 58.0
DTH2_k127_8673468_0 Catalyzes the conversion of chorismate to isochorismate K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001709 289.0
DTH2_k127_8673468_1 Protein PHYLLO, chloroplastic K14759 GO:0006732,GO:0006766,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010109,GO:0019222,GO:0031323,GO:0042180,GO:0042181,GO:0042372,GO:0042374,GO:0042548,GO:0042550,GO:0043467,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050789,GO:0050794,GO:0051186,GO:0051188,GO:0065007,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.2.1.9,4.2.1.113,4.2.99.20,5.4.4.2 0.000000000000000004824 86.0
DTH2_k127_8709752_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 413.0
DTH2_k127_8709752_1 oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000001326 214.0
DTH2_k127_8719178_0 Alpha galactosidase A K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 355.0
DTH2_k127_8719178_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 334.0
DTH2_k127_8719178_2 domain, Protein - - - 0.0000000183 65.0
DTH2_k127_8769456_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 413.0
DTH2_k127_8769456_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 315.0
DTH2_k127_8769456_2 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.000000000000000000000000000000000000000000000000000000000000000001297 233.0
DTH2_k127_8769456_3 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.0000000000000000000001482 96.0
DTH2_k127_8797803_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.498e-292 903.0
DTH2_k127_8797803_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
DTH2_k127_8797803_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005627 72.0
DTH2_k127_8797803_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006734 280.0
DTH2_k127_8797803_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
DTH2_k127_8797803_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000002073 212.0
DTH2_k127_8797803_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001932 182.0
DTH2_k127_8797803_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000001272 175.0
DTH2_k127_8797803_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000025 161.0
DTH2_k127_8797803_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000109 124.0
DTH2_k127_8797803_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000006507 126.0
DTH2_k127_8806050_0 aspartate kinase, monofunctional class K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 442.0
DTH2_k127_8806050_1 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000005367 195.0
DTH2_k127_8806050_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000001715 176.0
DTH2_k127_8806050_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000001202 145.0
DTH2_k127_8806050_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.0000000000000000000000006507 111.0
DTH2_k127_8806050_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 0.000000000000000000000005419 107.0
DTH2_k127_8806050_6 Tetratricopeptide repeat - - - 0.00000000001281 76.0
DTH2_k127_8838838_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000582 289.0
DTH2_k127_8841441_0 Dehydratase family K01687,K16786 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 583.0
DTH2_k127_8841441_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 332.0
DTH2_k127_8841441_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000101 182.0
DTH2_k127_8841441_3 - - - - 0.0000000000000000000000000001385 124.0
DTH2_k127_8841441_4 - - - - 0.000001554 52.0
DTH2_k127_8857250_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 397.0
DTH2_k127_8857250_1 protein kinase related protein - - - 0.000000000000000000000000000000004478 137.0
DTH2_k127_8857250_2 protein kinase related protein - - - 0.000000000000000000002217 98.0
DTH2_k127_8857250_3 PFAM Transcriptional regulator, histidine kinase sensor, histidine kinase internal region, ATP-binding region ATPase domain protein - - - 0.00001476 52.0
DTH2_k127_888165_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 432.0
DTH2_k127_888165_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 345.0
DTH2_k127_888165_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 329.0
DTH2_k127_888165_3 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
DTH2_k127_888165_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000001402 218.0
DTH2_k127_888165_5 PFAM regulatory protein, ArsR - - - 0.000000000000000000003927 96.0
DTH2_k127_888165_6 general stress protein - - - 0.00003435 52.0
DTH2_k127_8892113_0 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 382.0
DTH2_k127_8892113_1 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
DTH2_k127_8892113_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000001456 234.0
DTH2_k127_8892113_3 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000008209 231.0
DTH2_k127_8892113_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000007539 168.0
DTH2_k127_8892113_5 with chaperone activity ATP-binding K03696 - - 0.0000000000000000000000000000000000002613 146.0
DTH2_k127_8892113_6 Has endoribonuclease activity on mRNA K09022 - 3.5.99.10 0.0000000000000000000000000000000001959 136.0
DTH2_k127_8892113_7 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000008536 119.0
DTH2_k127_8892113_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000005406 82.0
DTH2_k127_8894508_0 Flotillin K07192 - - 5.561e-209 664.0
DTH2_k127_8894508_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000008372 221.0
DTH2_k127_8894508_2 GAF domain - - - 0.00000000000000000000000000000000000000000002016 175.0
DTH2_k127_8894508_3 - - - - 0.00000000000000000000000000000000002158 142.0
DTH2_k127_8894508_4 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000001938 133.0
DTH2_k127_8902711_0 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 355.0
DTH2_k127_8902711_1 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000002441 116.0
DTH2_k127_8902711_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000008075 106.0
DTH2_k127_8902711_3 Protein of unknown function (DUF503) K09764 - - 0.00000000000000001246 89.0
DTH2_k127_8902711_4 - - - - 0.00000000001112 69.0
DTH2_k127_8902711_5 Protein of unknown function (DUF3485) - - - 0.00000003762 63.0
DTH2_k127_8902711_6 Biopolymer transport protein ExbD/TolR - - - 0.000001604 55.0
DTH2_k127_8902711_7 inter-alpha-trypsin inhibitor heavy chain - GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.0001185 53.0
DTH2_k127_8997187_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 517.0
DTH2_k127_8997187_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000004392 164.0
DTH2_k127_9012013_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1111.0
DTH2_k127_9012013_1 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 408.0
DTH2_k127_9012013_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 300.0
DTH2_k127_9012013_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000202 162.0
DTH2_k127_9012013_4 Belongs to the bacterial histone-like protein family K03530,K05788 - - 0.00000000000000000000000000002262 120.0
DTH2_k127_9012013_5 Cold shock protein K03704 - - 0.000000000000000004143 85.0
DTH2_k127_9012013_6 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000003354 55.0
DTH2_k127_9013356_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.08e-242 767.0
DTH2_k127_9013356_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 8.919e-231 730.0
DTH2_k127_9013356_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000003032 176.0
DTH2_k127_9013356_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001435 175.0
DTH2_k127_9013356_12 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000009239 175.0
DTH2_k127_9013356_13 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001911 166.0
DTH2_k127_9013356_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000808 162.0
DTH2_k127_9013356_15 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001365 157.0
DTH2_k127_9013356_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001733 153.0
DTH2_k127_9013356_17 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000003679 144.0
DTH2_k127_9013356_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001147 139.0
DTH2_k127_9013356_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000006377 122.0
DTH2_k127_9013356_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 348.0
DTH2_k127_9013356_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000001063 100.0
DTH2_k127_9013356_21 Ribosomal protein S17 - - - 0.00000000000000000001603 93.0
DTH2_k127_9013356_22 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000003047 91.0
DTH2_k127_9013356_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000004263 85.0
DTH2_k127_9013356_24 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000008385 50.0
DTH2_k127_9013356_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 304.0
DTH2_k127_9013356_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
DTH2_k127_9013356_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
DTH2_k127_9013356_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
DTH2_k127_9013356_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
DTH2_k127_9013356_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000001838 190.0
DTH2_k127_9013356_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000002212 184.0
DTH2_k127_9024389_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 466.0
DTH2_k127_9024389_1 Peptidase C39 family - - - 0.00005491 54.0
DTH2_k127_9035532_0 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000003886 244.0
DTH2_k127_9035532_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
DTH2_k127_9035532_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000002707 140.0
DTH2_k127_9035532_3 general secretion pathway protein K02456 - - 0.000000000000000000000000000000002539 134.0
DTH2_k127_9037315_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 416.0
DTH2_k127_9037315_1 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000005809 213.0
DTH2_k127_9037315_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000002081 203.0
DTH2_k127_9037315_3 DUF167 K09131 - - 0.0000000000000003219 81.0
DTH2_k127_9084444_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.101e-197 633.0
DTH2_k127_9084444_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 456.0
DTH2_k127_9084444_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 411.0
DTH2_k127_9084444_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000002395 198.0
DTH2_k127_9084444_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000216 133.0
DTH2_k127_9109958_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003601 188.0
DTH2_k127_9134367_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 406.0
DTH2_k127_9134367_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
DTH2_k127_9134367_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000007822 252.0
DTH2_k127_9139653_0 Domain of unknown function (DUF5110) K01811 - 3.2.1.177 4.603e-218 698.0
DTH2_k127_9139653_1 Sulfate permease family K01673,K03321 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 587.0
DTH2_k127_9139653_2 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
DTH2_k127_9139653_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009497 245.0
DTH2_k127_9139653_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000005622 202.0
DTH2_k127_9139653_5 PFAM PPIC-type K03769 - 5.2.1.8 0.000000000000000000000000000000000000003003 157.0
DTH2_k127_9139653_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000001798 117.0
DTH2_k127_9139653_7 TPR Domain containing protein K12600 - - 0.000000000000000000000000005555 125.0
DTH2_k127_9139653_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000004981 113.0
DTH2_k127_9167055_0 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 431.0
DTH2_k127_9167055_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 378.0
DTH2_k127_9167055_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 371.0
DTH2_k127_9167055_3 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001221 286.0
DTH2_k127_9167055_4 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007022 275.0
DTH2_k127_9167055_5 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
DTH2_k127_9167055_6 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000004573 115.0
DTH2_k127_9167055_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000002463 108.0
DTH2_k127_9167055_8 YacP-like NYN domain K06962 - - 0.0000006891 57.0
DTH2_k127_91753_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 549.0
DTH2_k127_9185048_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 464.0
DTH2_k127_9185048_1 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 299.0
DTH2_k127_9185048_2 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000000000000001067 162.0
DTH2_k127_9185048_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000009732 74.0
DTH2_k127_9188769_0 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 382.0
DTH2_k127_9188769_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000006944 91.0
DTH2_k127_9199811_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1644.0
DTH2_k127_9199811_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1276.0
DTH2_k127_9199811_2 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 599.0
DTH2_k127_9199811_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 259.0
DTH2_k127_9199811_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
DTH2_k127_9199811_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000001111 206.0
DTH2_k127_9199811_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000009248 160.0
DTH2_k127_9199811_7 ribosomal protein l10 K02864 - - 0.00000000000000001333 89.0
DTH2_k127_9199811_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000006074 68.0
DTH2_k127_9199811_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000002536 60.0
DTH2_k127_9204719_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 310.0
DTH2_k127_9204719_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000006523 100.0
DTH2_k127_9204719_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000162 55.0
DTH2_k127_9220432_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 303.0
DTH2_k127_9220432_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007885 277.0
DTH2_k127_9220432_2 transport systems K02033 - - 0.0000000000000000000000000000000000000000000646 163.0
DTH2_k127_9229154_0 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 293.0
DTH2_k127_9229154_1 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000586 225.0
DTH2_k127_9229154_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000001918 61.0
DTH2_k127_9232126_0 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000005511 214.0
DTH2_k127_9232126_1 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000415 154.0
DTH2_k127_9232126_2 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000004431 140.0
DTH2_k127_9232126_3 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000005433 117.0
DTH2_k127_9250707_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.126e-242 767.0
DTH2_k127_9250707_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000002546 213.0
DTH2_k127_9262424_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 374.0
DTH2_k127_9262424_1 PFAM Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000002803 213.0
DTH2_k127_9336344_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 597.0
DTH2_k127_9336344_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 537.0
DTH2_k127_9336344_10 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000003578 130.0
DTH2_k127_9336344_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000001443 100.0
DTH2_k127_9336344_12 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000009603 87.0
DTH2_k127_9336344_13 - - - - 0.000001518 56.0
DTH2_k127_9336344_14 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000006386 53.0
DTH2_k127_9336344_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
DTH2_k127_9336344_3 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 426.0
DTH2_k127_9336344_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 377.0
DTH2_k127_9336344_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
DTH2_k127_9336344_6 Serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
DTH2_k127_9336344_7 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001335 265.0
DTH2_k127_9336344_8 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000002522 201.0
DTH2_k127_9336344_9 Transcriptional regulator - - - 0.000000000000000000000000000000002539 134.0
DTH2_k127_9337286_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 351.0
DTH2_k127_9337286_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000003337 112.0
DTH2_k127_9337286_2 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000003779 95.0
DTH2_k127_9382021_0 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 499.0
DTH2_k127_9382021_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000002311 196.0
DTH2_k127_9382021_10 - - - - 0.00001815 49.0
DTH2_k127_9382021_2 - - - - 0.0000000000000000000000006071 108.0
DTH2_k127_9382021_3 - - - - 0.000000000000000000001109 98.0
DTH2_k127_9382021_5 - - - - 0.0000000000000006346 79.0
DTH2_k127_9382021_6 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000001875 78.0
DTH2_k127_9382021_7 - - - - 0.0000000000526 64.0
DTH2_k127_9382021_8 - - - - 0.000000009564 56.0
DTH2_k127_9382021_9 CAAX protease self-immunity - - - 0.00000003808 64.0
DTH2_k127_9395213_0 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 296.0
DTH2_k127_9395213_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000001725 177.0
DTH2_k127_9395213_2 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.000000000000000001416 93.0
DTH2_k127_9395213_3 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000009961 78.0
DTH2_k127_9407539_0 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003778 254.0
DTH2_k127_9407539_1 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000002708 202.0
DTH2_k127_9407539_3 Belongs to the 'phage' integrase family - - - 0.0000000002232 65.0
DTH2_k127_9407539_4 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000001014 55.0
DTH2_k127_9475303_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.703e-277 868.0
DTH2_k127_9475303_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 371.0
DTH2_k127_9475303_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 297.0
DTH2_k127_9475303_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001962 274.0
DTH2_k127_9546312_0 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000003354 183.0
DTH2_k127_9546312_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000001069 110.0
DTH2_k127_9546312_2 Transcriptional regulator - - - 0.00000000000000000423 93.0
DTH2_k127_9568203_0 Heat shock 70 kDa protein K04043 - - 7.449e-274 855.0
DTH2_k127_9568203_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 465.0
DTH2_k127_9568203_2 PFAM Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
DTH2_k127_9568203_3 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain - - - 0.000000000001666 68.0
DTH2_k127_9684082_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 490.0
DTH2_k127_9684082_1 SMART Transcription regulator, AsnC-type - - - 0.00000000000000000000000000000000000001133 149.0
DTH2_k127_9684082_2 Cytochrome c K02198 - - 0.00000000000000001063 86.0
DTH2_k127_9684082_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000006805 82.0
DTH2_k127_9712368_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.438e-216 687.0
DTH2_k127_9712368_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 477.0
DTH2_k127_9712368_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000008141 134.0
DTH2_k127_9712368_3 Alternative locus ID - - - 0.00000000000000000000000000000001193 136.0
DTH2_k127_9712368_4 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000006708 128.0
DTH2_k127_9738671_0 transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005159 267.0
DTH2_k127_9738671_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000002361 211.0
DTH2_k127_9738671_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000664 159.0
DTH2_k127_9818079_0 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000862 197.0
DTH2_k127_9818079_1 - - - - 0.000000000002723 79.0
DTH2_k127_9883736_0 with chaperone activity ATP-binding K03696 - - 2.189e-216 678.0
DTH2_k127_9883736_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000006866 184.0
DTH2_k127_9885127_0 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 567.0
DTH2_k127_9893915_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 282.0
DTH2_k127_9893915_1 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000001766 159.0
DTH2_k127_9893915_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000002598 148.0
DTH2_k127_9893915_3 metal cluster binding K06940 - - 0.000000000000000000005789 99.0
DTH2_k127_9893915_4 DNA photolyase K01669 - 4.1.99.3 0.00000000000004751 74.0
DTH2_k127_9893915_5 photo-lyase K01669 GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 4.1.99.3 0.0000002493 52.0