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Overview

ID MAG00783
Name DTH2_bin.56
Sample SMP0023
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JACTUA01
Species
Assembly information
Completeness (%) 65.94
Contamination (%) 0.19
GC content (%) 66.0
N50 (bp) 3,143
Genome size (bp) 793,937

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes971

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_1148607_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 4.769e-198 630.0
DTH2_k127_1148607_1 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000008945 75.0
DTH2_k127_1148607_2 - - - - 0.0000007625 51.0
DTH2_k127_121112_0 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002703 254.0
DTH2_k127_121112_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000109 203.0
DTH2_k127_121112_2 - - - - 0.0000000000000000000000000000000000554 137.0
DTH2_k127_1274338_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 467.0
DTH2_k127_1274338_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000001173 181.0
DTH2_k127_1274338_2 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000001553 175.0
DTH2_k127_1284480_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 407.0
DTH2_k127_1284480_1 PFAM peptidase U32 K08303 - - 0.000000000000000003047 87.0
DTH2_k127_1284480_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000372 50.0
DTH2_k127_130541_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 489.0
DTH2_k127_130541_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 358.0
DTH2_k127_130541_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000004217 132.0
DTH2_k127_1312461_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 406.0
DTH2_k127_1312461_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 290.0
DTH2_k127_1312461_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007589 277.0
DTH2_k127_1312461_3 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005062 272.0
DTH2_k127_1312461_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
DTH2_k127_1312461_5 metallopeptidase activity - - - 0.00000000000000000000000000000000000002195 149.0
DTH2_k127_1352458_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 3.541e-217 685.0
DTH2_k127_1352458_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 497.0
DTH2_k127_1352458_10 Membrane protein of unknown function DUF63 - - - 0.0000000000002354 69.0
DTH2_k127_1352458_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 447.0
DTH2_k127_1352458_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 295.0
DTH2_k127_1352458_4 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
DTH2_k127_1352458_5 binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000000000000000001654 174.0
DTH2_k127_1352458_6 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000148 159.0
DTH2_k127_1352458_7 metal-binding protein - - - 0.0000000000000000000000000001029 119.0
DTH2_k127_1352458_8 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000000005625 107.0
DTH2_k127_1352458_9 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000004123 78.0
DTH2_k127_1364930_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 562.0
DTH2_k127_1364930_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000003923 121.0
DTH2_k127_1367120_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 1.063e-243 764.0
DTH2_k127_1367120_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 7.199e-207 652.0
DTH2_k127_1367120_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 347.0
DTH2_k127_1367120_3 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000005701 244.0
DTH2_k127_1367120_4 B-block binding subunit of TFIIIC - - - 0.000000000000000000000000000000000000000000001745 168.0
DTH2_k127_1367120_5 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000001972 141.0
DTH2_k127_1367120_6 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000004704 123.0
DTH2_k127_1367120_7 - - - - 0.0000000000008773 77.0
DTH2_k127_1367120_8 - - - - 0.000000006188 65.0
DTH2_k127_1374085_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 604.0
DTH2_k127_1374085_1 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 565.0
DTH2_k127_1374085_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000004465 158.0
DTH2_k127_1374085_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000002765 97.0
DTH2_k127_1374085_4 - K06868 - 2.5.1.73 0.0000000000005584 70.0
DTH2_k127_1374085_5 Tetratricopeptide repeat - - - 0.0000000000008622 74.0
DTH2_k127_1382968_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 5.017e-208 656.0
DTH2_k127_1382968_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 524.0
DTH2_k127_1396738_0 Ferrous iron transport B domain protein K04759 - - 1.047e-211 683.0
DTH2_k127_1396738_1 iron dependent repressor K03709,K04758 - - 0.000000000000000000000000000000000000008679 153.0
DTH2_k127_1396738_2 Helix-hairpin-helix domain K02347 - - 0.0009972 45.0
DTH2_k127_1431245_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 466.0
DTH2_k127_1431245_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 411.0
DTH2_k127_1431245_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
DTH2_k127_1431245_3 EamA-like transporter family - - - 0.00000000000000005941 86.0
DTH2_k127_1431245_4 - - - - 0.0000000000000008044 83.0
DTH2_k127_1433466_0 STAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 591.0
DTH2_k127_1454555_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 1.835e-227 708.0
DTH2_k127_1454555_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 383.0
DTH2_k127_1485554_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004994 241.0
DTH2_k127_1485554_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
DTH2_k127_1485554_2 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000001446 223.0
DTH2_k127_1485554_3 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000000000164 167.0
DTH2_k127_148647_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 590.0
DTH2_k127_148647_1 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 469.0
DTH2_k127_1489848_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 305.0
DTH2_k127_1489848_1 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000418 121.0
DTH2_k127_1489848_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000002992 93.0
DTH2_k127_1490903_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 439.0
DTH2_k127_1490903_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000182 187.0
DTH2_k127_1490903_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000008355 102.0
DTH2_k127_1515257_0 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 419.0
DTH2_k127_1515257_1 - - - - 0.0000000000000000000000000000000001958 137.0
DTH2_k127_1515257_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000008756 119.0
DTH2_k127_1515257_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00003726 47.0
DTH2_k127_1517987_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.454e-244 762.0
DTH2_k127_1517987_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 339.0
DTH2_k127_1517987_2 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 314.0
DTH2_k127_1517987_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000002463 92.0
DTH2_k127_1598444_0 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 359.0
DTH2_k127_1598444_1 Domain of unknown function (DUF1858) - - - 0.00000000000000000000002082 100.0
DTH2_k127_1604286_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
DTH2_k127_1604286_1 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 361.0
DTH2_k127_1604286_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
DTH2_k127_1614243_0 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 436.0
DTH2_k127_1614243_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 327.0
DTH2_k127_1614243_2 PDGLE domain K02009 - - 0.000000000000000000000000000000000001782 142.0
DTH2_k127_1614243_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000001865 59.0
DTH2_k127_1614243_4 hydrolase K04794 - 3.1.1.29 0.0000008533 62.0
DTH2_k127_1614808_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 401.0
DTH2_k127_1614808_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000002554 108.0
DTH2_k127_1614808_2 - - - - 0.00000000008011 62.0
DTH2_k127_1632872_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 7.428e-217 677.0
DTH2_k127_1632872_1 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
DTH2_k127_1632872_2 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000003537 227.0
DTH2_k127_1632872_3 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000000003494 198.0
DTH2_k127_1646154_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 442.0
DTH2_k127_1646154_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
DTH2_k127_1704517_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 411.0
DTH2_k127_1704517_1 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 295.0
DTH2_k127_1704517_2 Domain of unknown function (DUF1917) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 288.0
DTH2_k127_1721423_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 555.0
DTH2_k127_1721423_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000011 275.0
DTH2_k127_1721423_2 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004541 258.0
DTH2_k127_1721423_3 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000007852 203.0
DTH2_k127_1721423_4 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000007338 212.0
DTH2_k127_1721423_5 chorismate mutase K04093 - 5.4.99.5 0.000000000000000000000000597 110.0
DTH2_k127_1721423_6 PFAM NADPH-dependent FMN reductase - - - 0.000000000005295 67.0
DTH2_k127_1753245_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 371.0
DTH2_k127_1753245_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003273 269.0
DTH2_k127_1753245_2 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000007957 85.0
DTH2_k127_1849764_0 Domain of unknown function DUF128 K21640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 325.0
DTH2_k127_1849764_1 PFAM transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000001032 220.0
DTH2_k127_1849764_2 - - - - 0.00000000000000000000000000000000000000000000000001983 186.0
DTH2_k127_1852001_0 Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 419.0
DTH2_k127_1852001_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 342.0
DTH2_k127_1852001_2 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 299.0
DTH2_k127_1852001_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 260.0
DTH2_k127_1895856_0 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 351.0
DTH2_k127_1895856_1 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 312.0
DTH2_k127_1895856_2 PHP C-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 266.0
DTH2_k127_1895856_3 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000000003403 176.0
DTH2_k127_1895856_4 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000000007634 107.0
DTH2_k127_1895856_5 protein conserved in archaea K09723 - - 0.0000000000000000001439 93.0
DTH2_k127_1895856_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000002072 74.0
DTH2_k127_189741_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 474.0
DTH2_k127_189741_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 386.0
DTH2_k127_189741_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005866 276.0
DTH2_k127_189741_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000902 271.0
DTH2_k127_189741_4 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000005159 169.0
DTH2_k127_189741_5 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.000000000000000000000002136 119.0
DTH2_k127_1925170_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 331.0
DTH2_k127_1925170_1 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000008913 223.0
DTH2_k127_1925170_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000001024 210.0
DTH2_k127_1925170_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000002916 141.0
DTH2_k127_1943910_0 acid binding OB-fold tRNA helicase-type K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 518.0
DTH2_k127_1943910_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 453.0
DTH2_k127_1943910_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 290.0
DTH2_k127_19513_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 466.0
DTH2_k127_19513_1 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000002272 186.0
DTH2_k127_19513_2 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000002882 99.0
DTH2_k127_1959041_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 2.121e-238 745.0
DTH2_k127_196449_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 1.323e-196 624.0
DTH2_k127_2113992_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000005366 234.0
DTH2_k127_2113992_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000001739 226.0
DTH2_k127_2113992_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000001149 156.0
DTH2_k127_2151352_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 443.0
DTH2_k127_2151352_1 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 344.0
DTH2_k127_2156868_0 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
DTH2_k127_2156868_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 334.0
DTH2_k127_2156868_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001113 282.0
DTH2_k127_2156868_3 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008855 258.0
DTH2_k127_2156868_4 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000375 236.0
DTH2_k127_2156868_5 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000004482 152.0
DTH2_k127_2205942_0 V-type ATPase 116kDa subunit family K02123 - - 3.426e-222 706.0
DTH2_k127_2205942_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000002273 232.0
DTH2_k127_2205942_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000001969 136.0
DTH2_k127_2205942_3 ATP synthase subunit C K02124 - - 0.000000000000000000001167 95.0
DTH2_k127_2205942_4 H subunit K02107 - - 0.000009945 52.0
DTH2_k127_2266975_0 PFAM PilT protein domain protein K06865 - - 6.986e-226 710.0
DTH2_k127_2266975_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000577 286.0
DTH2_k127_2473800_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 443.0
DTH2_k127_2473800_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
DTH2_k127_2473800_2 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000007624 93.0
DTH2_k127_2533809_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 565.0
DTH2_k127_2533809_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 386.0
DTH2_k127_2533809_2 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 346.0
DTH2_k127_2533809_3 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004052 284.0
DTH2_k127_2533809_4 PAS domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000001071 248.0
DTH2_k127_2533809_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
DTH2_k127_2533809_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000195 86.0
DTH2_k127_2533809_7 - - - - 0.00000000000007904 79.0
DTH2_k127_2533809_8 PFAM Tetratricopeptide repeat - - - 0.000000006146 66.0
DTH2_k127_2580354_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
DTH2_k127_2580354_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 336.0
DTH2_k127_2580354_2 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002401 254.0
DTH2_k127_2580354_3 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000004076 155.0
DTH2_k127_2580354_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000003022 124.0
DTH2_k127_2600250_0 domain, Protein K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 561.0
DTH2_k127_2600250_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001788 248.0
DTH2_k127_2600250_2 Sulphur transport K07112 - - 0.000000000000000005424 84.0
DTH2_k127_2619037_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 409.0
DTH2_k127_2619037_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000001717 234.0
DTH2_k127_2619037_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000002708 120.0
DTH2_k127_2639575_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 3.935e-305 942.0
DTH2_k127_2639575_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 1.846e-203 640.0
DTH2_k127_2639575_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 376.0
DTH2_k127_2639575_3 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 329.0
DTH2_k127_2639575_4 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
DTH2_k127_2639575_5 PFAM molydopterin dinucleotide-binding region K00201,K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.0000000000000000000000005166 108.0
DTH2_k127_2644968_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 564.0
DTH2_k127_2644968_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 291.0
DTH2_k127_2657512_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 1.013e-295 914.0
DTH2_k127_2657512_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 439.0
DTH2_k127_2657745_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 357.0
DTH2_k127_2657745_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000002144 151.0
DTH2_k127_2657745_2 - - - - 0.000000000000000006613 84.0
DTH2_k127_2664297_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 497.0
DTH2_k127_2664297_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
DTH2_k127_2670103_0 acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 527.0
DTH2_k127_2670103_1 CBS domain containing protein K03699 - - 0.000000000000000000000000000004653 122.0
DTH2_k127_2673274_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1427.0
DTH2_k127_2673274_1 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 305.0
DTH2_k127_2673274_2 PFAM PRC-barrel domain - - - 0.000000000000000000000000000001571 123.0
DTH2_k127_2679294_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1254.0
DTH2_k127_2679294_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0004828 44.0
DTH2_k127_2694403_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 374.0
DTH2_k127_2694403_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 314.0
DTH2_k127_2694403_2 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001833 264.0
DTH2_k127_2694403_3 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000004632 193.0
DTH2_k127_2699875_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000009527 177.0
DTH2_k127_2699875_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000001982 162.0
DTH2_k127_2699875_2 - - - - 0.00000000000007463 81.0
DTH2_k127_2702018_0 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 337.0
DTH2_k127_2702018_1 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
DTH2_k127_2702018_2 Protein of unknown function (DUF424) K09148 - - 0.00000000000728 66.0
DTH2_k127_2741571_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.077e-248 780.0
DTH2_k127_2741571_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 510.0
DTH2_k127_2741571_2 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
DTH2_k127_2741571_3 transferase hexapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000976 273.0
DTH2_k127_2741571_4 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000003529 134.0
DTH2_k127_2743049_0 PFAM type II secretion system protein E K07332 - - 3.221e-287 904.0
DTH2_k127_2743049_1 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000176 69.0
DTH2_k127_2747947_0 KH, type 1, domain K07041 - - 8.846e-269 832.0
DTH2_k127_2747947_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 325.0
DTH2_k127_2747947_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 298.0
DTH2_k127_2753656_0 Protein of unknown function (DUF460) K09150 - - 1.489e-223 714.0
DTH2_k127_2753656_1 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 384.0
DTH2_k127_2753656_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 321.0
DTH2_k127_2753656_3 PFAM PP-loop domain protein - - - 0.000000000000000000000000003587 115.0
DTH2_k127_2766638_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 586.0
DTH2_k127_2766638_1 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 527.0
DTH2_k127_2766638_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000001505 246.0
DTH2_k127_2766638_3 Histidine kinase - - - 0.00000000000000000000000000000000000002203 167.0
DTH2_k127_2766638_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000001252 58.0
DTH2_k127_2797387_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 258.0
DTH2_k127_2797387_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000008346 204.0
DTH2_k127_2813679_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.673e-219 692.0
DTH2_k127_2813679_1 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 599.0
DTH2_k127_2813679_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
DTH2_k127_2813679_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000002475 153.0
DTH2_k127_2829533_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 595.0
DTH2_k127_2829533_1 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 454.0
DTH2_k127_2829533_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 325.0
DTH2_k127_2829533_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
DTH2_k127_2829533_4 Helix-turn-helix domain protein K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004352 253.0
DTH2_k127_2840020_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.654e-212 668.0
DTH2_k127_2840020_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000004274 129.0
DTH2_k127_2852752_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 547.0
DTH2_k127_2852752_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000001505 195.0
DTH2_k127_2864420_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
DTH2_k127_2864420_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
DTH2_k127_2864420_2 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000114 191.0
DTH2_k127_2864420_3 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000002843 160.0
DTH2_k127_2864420_4 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000002828 141.0
DTH2_k127_3054526_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.078e-247 773.0
DTH2_k127_3054526_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.000000000000000000000000000000267 126.0
DTH2_k127_3056961_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.231e-272 849.0
DTH2_k127_3056961_1 PFAM CBS domain - - - 3.951e-237 741.0
DTH2_k127_3056961_2 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000225 290.0
DTH2_k127_3056961_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000001279 187.0
DTH2_k127_3056961_4 zinc finger, SWIM - - - 0.0000000000000000000000000006155 119.0
DTH2_k127_3056961_5 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000004438 101.0
DTH2_k127_3102218_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 419.0
DTH2_k127_3102218_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000001967 157.0
DTH2_k127_3142175_0 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 366.0
DTH2_k127_3142175_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000009651 202.0
DTH2_k127_3142175_2 Protein of unknown function (DUF1622) - - - 0.000000000000000000000007793 105.0
DTH2_k127_3142175_3 Belongs to the UPF0305 family K07012 - - 0.00000000000000138 78.0
DTH2_k127_3169437_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 377.0
DTH2_k127_3171982_0 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 314.0
DTH2_k127_3171982_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000002071 211.0
DTH2_k127_3171982_2 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000002929 171.0
DTH2_k127_329703_0 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000001084 229.0
DTH2_k127_329703_1 - - - - 0.0000000000000000000000000000000000000000000000000003298 192.0
DTH2_k127_329703_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000003948 128.0
DTH2_k127_3340584_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 444.0
DTH2_k127_3340584_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 312.0
DTH2_k127_3340584_2 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 306.0
DTH2_k127_3340584_3 Yip1 domain - - - 0.000000000000000000000000000000000000000256 157.0
DTH2_k127_3340584_4 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000001745 130.0
DTH2_k127_3340584_5 - - - - 0.000000000000008896 83.0
DTH2_k127_3347071_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.725e-211 664.0
DTH2_k127_3347071_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000171 154.0
DTH2_k127_3356890_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
DTH2_k127_3356890_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 379.0
DTH2_k127_3367979_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 522.0
DTH2_k127_3367979_1 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 307.0
DTH2_k127_3367979_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000002996 211.0
DTH2_k127_3367979_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000819 123.0
DTH2_k127_3367979_4 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000003473 63.0
DTH2_k127_3494757_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 563.0
DTH2_k127_3494757_1 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 500.0
DTH2_k127_3494757_2 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 318.0
DTH2_k127_3506082_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1241.0
DTH2_k127_3506082_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000006164 104.0
DTH2_k127_3506082_2 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0000000000000000000004727 98.0
DTH2_k127_353360_0 Belongs to the MCM family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 374.0
DTH2_k127_353360_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 346.0
DTH2_k127_3555851_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 573.0
DTH2_k127_3555851_1 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 398.0
DTH2_k127_3653892_0 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 326.0
DTH2_k127_3653892_1 Sugar efflux transporter for intercellular exchange K15383 - - 0.000000000000000000002377 97.0
DTH2_k127_3653892_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000001992 75.0
DTH2_k127_3653892_3 Protein of unknown function (DUF1624) - - - 0.00008133 54.0
DTH2_k127_3740271_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
DTH2_k127_3740271_1 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
DTH2_k127_3740271_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000001008 178.0
DTH2_k127_3740271_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000002082 167.0
DTH2_k127_3740271_4 PFAM Ribosomal protein K02912 - - 0.0000000000000000000000000000001789 134.0
DTH2_k127_379864_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 532.0
DTH2_k127_379864_1 Belongs to the UPF0235 family K09131 - - 0.00000000000000000007515 91.0
DTH2_k127_3808631_0 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 320.0
DTH2_k127_3808631_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 306.0
DTH2_k127_3808631_2 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000001983 156.0
DTH2_k127_3812131_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.371e-228 719.0
DTH2_k127_3812131_1 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 364.0
DTH2_k127_3812131_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001219 278.0
DTH2_k127_3812131_3 ribosomal protein S15 K02956 - - 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
DTH2_k127_3812131_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000531 63.0
DTH2_k127_3812131_5 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.00001349 52.0
DTH2_k127_3814466_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
DTH2_k127_3814466_1 WD-40 repeat - - - 0.00000000000000000000000000001827 133.0
DTH2_k127_3814466_2 - - - - 0.0000000000001028 83.0
DTH2_k127_3824464_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 467.0
DTH2_k127_3824464_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
DTH2_k127_3824464_2 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000001121 225.0
DTH2_k127_3824464_3 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000001554 195.0
DTH2_k127_3826286_0 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000001531 218.0
DTH2_k127_3826286_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000001208 153.0
DTH2_k127_3826286_2 - - - - 0.000000000000000000002973 100.0
DTH2_k127_3844795_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 448.0
DTH2_k127_3844795_1 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
DTH2_k127_3867694_0 PFAM Linocin_M18 bacteriocin protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006849 241.0
DTH2_k127_3867694_1 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000001232 205.0
DTH2_k127_3867694_2 - - - - 0.000000000000000000000000000000000000000000000000008902 194.0
DTH2_k127_3867694_3 Rubrerythrin - - - 0.00000000000000000000000000000000000004041 148.0
DTH2_k127_3867694_4 - - - - 0.0004358 51.0
DTH2_k127_3875295_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 599.0
DTH2_k127_3875295_1 - - - - 0.000000000000000000000000000000000000000000000001776 179.0
DTH2_k127_3875295_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000001815 159.0
DTH2_k127_3875295_3 - - - - 0.0000000000000000000000000004128 120.0
DTH2_k127_3880792_0 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000005961 212.0
DTH2_k127_3886856_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1193.0
DTH2_k127_3886856_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000007235 182.0
DTH2_k127_3886856_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000001093 176.0
DTH2_k127_3886856_3 TIR domain - - - 0.000000001817 64.0
DTH2_k127_3887370_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 533.0
DTH2_k127_3887370_1 Belongs to the P(II) protein family K04751 - - 0.000000000000000000176 88.0
DTH2_k127_3887370_2 - - - - 0.0000001009 53.0
DTH2_k127_3888673_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 366.0
DTH2_k127_3888673_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 308.0
DTH2_k127_3888673_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000006994 145.0
DTH2_k127_3888673_3 - - - - 0.0000000000000000000000000004069 116.0
DTH2_k127_3891156_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 370.0
DTH2_k127_3891156_1 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
DTH2_k127_3891156_2 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000000000000000000000000001413 180.0
DTH2_k127_3908898_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 409.0
DTH2_k127_3908898_1 Formamidopyrimidine-DNA glycosylase H2TH domain - - - 0.0000000000000000000000000000000000002811 149.0
DTH2_k127_3908898_2 heme oxygenase (decyclizing) activity - - - 0.0000000000000005664 85.0
DTH2_k127_3932190_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 557.0
DTH2_k127_3932190_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000005868 126.0
DTH2_k127_3956145_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 443.0
DTH2_k127_3956145_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 371.0
DTH2_k127_3956145_2 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000002026 216.0
DTH2_k127_3956145_3 PFAM Abortive infection protein - - - 0.00000000000008288 82.0
DTH2_k127_3956759_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.28e-219 712.0
DTH2_k127_3956759_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.768e-209 661.0
DTH2_k127_3956759_2 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 392.0
DTH2_k127_3956759_3 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000004341 222.0
DTH2_k127_3956759_4 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000000005068 190.0
DTH2_k127_3985286_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 510.0
DTH2_k127_3985286_1 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 311.0
DTH2_k127_3985286_2 PFAM TspO MBR family K05770 - - 0.00000000000000000000000000000000000000002131 157.0
DTH2_k127_3985286_3 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000000000000000000001308 145.0
DTH2_k127_4016193_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.66e-206 650.0
DTH2_k127_4016193_1 Thioredoxin K03671 - - 0.00000000000000000000000000000000000001625 150.0
DTH2_k127_4016193_2 binds to the 23S rRNA K02922 - - 0.000000000000000000000001377 103.0
DTH2_k127_4047053_0 TGS domain protein K06942 - - 0.000000000000000000000000000000000000000000005177 164.0
DTH2_k127_4047053_1 - - - - 0.0000000000000000000000000000000000000002542 154.0
DTH2_k127_4047053_2 - - - - 0.00000000000000000000006694 104.0
DTH2_k127_4047053_3 - - - - 0.0000000001057 66.0
DTH2_k127_4091510_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 593.0
DTH2_k127_4109111_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 371.0
DTH2_k127_4109111_1 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.0000000000000000000000000000000000000000000000000000000000002645 218.0
DTH2_k127_4109111_2 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000005207 211.0
DTH2_k127_4110015_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 2.427e-204 648.0
DTH2_k127_4110015_1 F420-non-reducing hydrogenase subunit G K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 493.0
DTH2_k127_4110015_2 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
DTH2_k127_4110015_3 Roadblock LC7 K07131 - - 0.0000000000000000000000000000000000000000000000004617 177.0
DTH2_k127_4110015_4 - - - - 0.0000000000000000000000000000000000000000000002037 175.0
DTH2_k127_4110015_5 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000001388 142.0
DTH2_k127_4110015_6 - - - - 0.00006791 54.0
DTH2_k127_4156611_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 377.0
DTH2_k127_4156611_1 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001016 282.0
DTH2_k127_4156611_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000469 198.0
DTH2_k127_4156611_3 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000002654 160.0
DTH2_k127_4177746_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 359.0
DTH2_k127_4177746_1 methylase K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 333.0
DTH2_k127_4179495_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 599.0
DTH2_k127_4179495_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 417.0
DTH2_k127_4179495_10 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000137 93.0
DTH2_k127_4179495_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000000000000002833 90.0
DTH2_k127_4179495_12 Probably involved in the biogenesis of the ribosome K14561 - - 0.0000000000000001616 86.0
DTH2_k127_4179495_13 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000001504 74.0
DTH2_k127_4179495_2 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 368.0
DTH2_k127_4179495_3 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 324.0
DTH2_k127_4179495_4 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 295.0
DTH2_k127_4179495_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000006099 226.0
DTH2_k127_4179495_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000000000000000000000000000000000155 180.0
DTH2_k127_4179495_7 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000000002137 149.0
DTH2_k127_4179495_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00000000000000000000000000003255 126.0
DTH2_k127_4179495_9 - - - - 0.000000000000000000000008757 102.0
DTH2_k127_4216244_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 7.673e-208 657.0
DTH2_k127_4216244_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 523.0
DTH2_k127_4216244_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000002402 163.0
DTH2_k127_4216244_3 beta-lactamase domain protein - - - 0.000000000000004924 82.0
DTH2_k127_4216244_4 Metallo-beta-lactamase superfamily - - - 0.000000000005249 72.0
DTH2_k127_4216244_5 Metallo-beta-lactamase superfamily - - - 0.0002024 51.0
DTH2_k127_4225887_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 582.0
DTH2_k127_4225887_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 379.0
DTH2_k127_4225887_2 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000482 271.0
DTH2_k127_4225887_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000003816 258.0
DTH2_k127_4225887_4 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000005036 233.0
DTH2_k127_4225887_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000001049 233.0
DTH2_k127_4225887_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000004976 195.0
DTH2_k127_4238795_0 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.112e-248 779.0
DTH2_k127_4238795_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.795e-216 680.0
DTH2_k127_4238795_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 468.0
DTH2_k127_4238795_3 - - - - 0.000000000000000000000000000000000000000000006078 169.0
DTH2_k127_4238795_4 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000001965 85.0
DTH2_k127_4294796_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 504.0
DTH2_k127_4294796_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000004283 156.0
DTH2_k127_4294796_2 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000003319 89.0
DTH2_k127_43100_0 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000001001 226.0
DTH2_k127_43100_1 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000007639 192.0
DTH2_k127_43100_2 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000002367 113.0
DTH2_k127_4338837_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000005741 240.0
DTH2_k127_4338837_1 NTPase - - - 0.0000000000000000000000000000000000000003509 155.0
DTH2_k127_4338837_2 DEAD DEAH box helicase K06877 - - 0.0000000000000000000000008377 106.0
DTH2_k127_4345533_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 429.0
DTH2_k127_4345533_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 282.0
DTH2_k127_4345533_2 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
DTH2_k127_4345533_3 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000124 136.0
DTH2_k127_4349751_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.448e-206 658.0
DTH2_k127_4349751_1 Ras family K06945 - - 0.00000000000000000000000000000000000000000000000000003376 193.0
DTH2_k127_4349751_2 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000126 138.0
DTH2_k127_4349751_4 - - - - 0.000000000000005276 80.0
DTH2_k127_44710_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 471.0
DTH2_k127_44710_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
DTH2_k127_44710_2 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 301.0
DTH2_k127_44710_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
DTH2_k127_44710_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000000000000000000000000000002527 239.0
DTH2_k127_44710_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000002042 134.0
DTH2_k127_44710_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000001877 95.0
DTH2_k127_4478441_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000001591 192.0
DTH2_k127_4478441_1 COG0457 FOG TPR repeat - - - 0.000000002634 70.0
DTH2_k127_4495571_0 DEAD DEAH box helicase K06877 - - 1.088e-244 769.0
DTH2_k127_4539359_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.161e-316 978.0
DTH2_k127_4539359_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.014e-244 762.0
DTH2_k127_4539359_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 572.0
DTH2_k127_4539359_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
DTH2_k127_4539359_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000001851 191.0
DTH2_k127_4539359_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000000000000000000012 160.0
DTH2_k127_4539359_6 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000003907 81.0
DTH2_k127_4604225_0 Male sterility protein K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
DTH2_k127_4604225_1 Group 1 family - - - 0.0000000000000000000000000000000000000000000008322 179.0
DTH2_k127_4619629_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.714e-209 664.0
DTH2_k127_4619629_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.356e-207 660.0
DTH2_k127_4619629_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002639 278.0
DTH2_k127_4778913_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.845e-217 685.0
DTH2_k127_4794365_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 413.0
DTH2_k127_4794365_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
DTH2_k127_4887208_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 583.0
DTH2_k127_4887208_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 550.0
DTH2_k127_4887208_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 313.0
DTH2_k127_4887208_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004342 254.0
DTH2_k127_4887208_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000001218 201.0
DTH2_k127_4914212_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001592 270.0
DTH2_k127_4914212_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000008872 179.0
DTH2_k127_4914212_2 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000007842 69.0
DTH2_k127_4930388_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
DTH2_k127_4930388_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000969 205.0
DTH2_k127_4930388_2 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000001365 143.0
DTH2_k127_4930388_3 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000001083 134.0
DTH2_k127_4930388_4 structural constituent of ribosome K02924 - - 0.000000000000000005855 85.0
DTH2_k127_4930388_5 CRS1_YhbY K07574 - - 0.0000000005986 61.0
DTH2_k127_50213_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 473.0
DTH2_k127_50213_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004034 261.0
DTH2_k127_50213_2 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000001509 220.0
DTH2_k127_5046996_0 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 529.0
DTH2_k127_5046996_1 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003897 247.0
DTH2_k127_5046996_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000005096 119.0
DTH2_k127_5059005_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 9.149e-210 657.0
DTH2_k127_5059005_1 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 306.0
DTH2_k127_5059005_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 281.0
DTH2_k127_5059005_3 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000000000000006276 197.0
DTH2_k127_5059005_4 Large family of predicted nucleotide-binding domains K07158 - - 0.0000000000000000000000000000000002853 142.0
DTH2_k127_5059005_5 Transcriptional regulator K07722 - - 0.000000000000000000000000000002283 128.0
DTH2_k127_5059005_6 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000143 110.0
DTH2_k127_5059005_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000007049 106.0
DTH2_k127_5059005_8 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000000001682 94.0
DTH2_k127_5063571_0 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 437.0
DTH2_k127_5063571_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000000000000000000000000000000000000000000001129 230.0
DTH2_k127_5063571_2 - - - - 0.00000000000000000000000000000000000008725 151.0
DTH2_k127_5079946_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 318.0
DTH2_k127_5079946_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000007412 238.0
DTH2_k127_5082469_0 Belongs to the RtcB family K14415 - 6.5.1.3 9.272e-218 684.0
DTH2_k127_5082469_1 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 338.0
DTH2_k127_5082469_2 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
DTH2_k127_5082469_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000001845 126.0
DTH2_k127_5082469_4 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000005728 121.0
DTH2_k127_5082469_5 - - - - 0.0000000000000000000000002626 117.0
DTH2_k127_5082469_6 - - - - 0.00000000000000000000006617 104.0
DTH2_k127_5103878_0 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 533.0
DTH2_k127_5103878_1 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 351.0
DTH2_k127_5103878_2 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000006337 192.0
DTH2_k127_5103878_3 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000000001526 143.0
DTH2_k127_5109127_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
DTH2_k127_5109127_1 - - - - 0.00000000000005742 81.0
DTH2_k127_5110700_0 Radical SAM ThiC family K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 491.0
DTH2_k127_5110700_1 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 344.0
DTH2_k127_5110700_2 - - - - 0.0000000000000000000000000000000000007918 145.0
DTH2_k127_5132185_0 COG1668 ABC-type Na efflux pump, permease component - - - 2.808e-204 652.0
DTH2_k127_5132185_1 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 430.0
DTH2_k127_5132185_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 369.0
DTH2_k127_5132185_3 META domain - - - 0.0000000000000000007736 92.0
DTH2_k127_513697_0 PFAM TrkA-N domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 471.0
DTH2_k127_513697_1 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 394.0
DTH2_k127_513697_2 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 294.0
DTH2_k127_5139716_0 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 329.0
DTH2_k127_5139716_1 LemA family K03744 - - 0.000000000001648 76.0
DTH2_k127_5139716_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000001811 53.0
DTH2_k127_5146523_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 478.0
DTH2_k127_5146523_1 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000573 92.0
DTH2_k127_5175652_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 2.957e-274 846.0
DTH2_k127_5175652_1 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 532.0
DTH2_k127_5175652_2 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 507.0
DTH2_k127_5175652_3 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 498.0
DTH2_k127_5175652_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 451.0
DTH2_k127_5175652_5 Coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.000000000000000000000000000000000000000000002232 170.0
DTH2_k127_5176584_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 392.0
DTH2_k127_5176584_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 388.0
DTH2_k127_5176584_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000008831 106.0
DTH2_k127_5183834_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 524.0
DTH2_k127_5183834_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 498.0
DTH2_k127_5183834_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
DTH2_k127_5183834_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
DTH2_k127_5183834_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000001231 84.0
DTH2_k127_5184454_0 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 424.0
DTH2_k127_5184454_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 373.0
DTH2_k127_5184454_2 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000001843 158.0
DTH2_k127_5184454_3 protein conserved in archaea - - - 0.000000000000000000000000001899 120.0
DTH2_k127_5223789_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 450.0
DTH2_k127_5234363_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1043.0
DTH2_k127_5234363_2 Chromate transporter K07240 - - 0.000000000414 61.0
DTH2_k127_5302901_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 421.0
DTH2_k127_5302901_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002807 218.0
DTH2_k127_5330555_0 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008181 271.0
DTH2_k127_5330555_1 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000347 179.0
DTH2_k127_5330555_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000003521 129.0
DTH2_k127_535762_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.068e-220 697.0
DTH2_k127_535762_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000002391 164.0
DTH2_k127_535762_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000004478 63.0
DTH2_k127_5359087_0 AIR synthase related protein domain protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 393.0
DTH2_k127_5359087_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008019 270.0
DTH2_k127_5359087_2 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 267.0
DTH2_k127_5359087_3 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
DTH2_k127_5359087_4 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
DTH2_k127_5359087_5 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000002647 64.0
DTH2_k127_5381519_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 610.0
DTH2_k127_5381519_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 384.0
DTH2_k127_5381519_2 - - - - 0.0000000000000000000000000000000000000002785 161.0
DTH2_k127_5381519_3 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00001595 48.0
DTH2_k127_5389918_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001496 275.0
DTH2_k127_5389918_1 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000156 253.0
DTH2_k127_5389918_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000006495 208.0
DTH2_k127_5458468_0 PFAM ABC transporter K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000001894 233.0
DTH2_k127_5458468_1 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000001214 233.0
DTH2_k127_5458468_2 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000000001044 196.0
DTH2_k127_5458468_3 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000009613 164.0
DTH2_k127_5458468_4 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000009603 87.0
DTH2_k127_5488299_0 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 406.0
DTH2_k127_5488299_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000003518 186.0
DTH2_k127_5488299_2 PAS domain - - - 0.000000000000000000000000000000000000006143 154.0
DTH2_k127_5526772_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 370.0
DTH2_k127_5526772_1 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002423 270.0
DTH2_k127_5526772_2 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000009645 237.0
DTH2_k127_5585995_0 in RNase L inhibitor, RLI K06174 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 579.0
DTH2_k127_5601808_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.98e-297 919.0
DTH2_k127_5601808_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.937e-251 783.0
DTH2_k127_5601808_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
DTH2_k127_5601808_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000006113 168.0
DTH2_k127_5601808_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000001177 72.0
DTH2_k127_5615127_0 peptidyl-tyrosine sulfation - - - 1.411e-263 853.0
DTH2_k127_5615127_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 507.0
DTH2_k127_5615127_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000006398 121.0
DTH2_k127_5679747_0 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003792 278.0
DTH2_k127_5679747_1 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000329 213.0
DTH2_k127_5679747_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000009886 143.0
DTH2_k127_5679747_3 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000001371 138.0
DTH2_k127_5707549_0 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 406.0
DTH2_k127_5779245_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
DTH2_k127_5779245_1 - - - - 0.0000000000000000006287 93.0
DTH2_k127_5823456_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.795e-297 919.0
DTH2_k127_5827191_0 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 366.0
DTH2_k127_5827191_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
DTH2_k127_5827191_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000268 228.0
DTH2_k127_591238_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.285e-273 852.0
DTH2_k127_591238_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000312 165.0
DTH2_k127_591238_2 - - - - 0.00000000000000000000000000000000000005483 147.0
DTH2_k127_591238_3 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000007037 152.0
DTH2_k127_591238_4 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000001387 132.0
DTH2_k127_591238_5 extracellular matrix structural constituent - - - 0.000006541 53.0
DTH2_k127_5913172_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 389.0
DTH2_k127_5913172_1 - - - - 0.000000000000000000000000000001248 123.0
DTH2_k127_5913172_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000001953 73.0
DTH2_k127_5913172_3 but it may be involved in stabilization of the trimeric complex - - - 0.00000000000006237 72.0
DTH2_k127_6189465_0 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 515.0
DTH2_k127_6189465_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
DTH2_k127_6201456_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000003037 239.0
DTH2_k127_6201456_1 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000005162 168.0
DTH2_k127_6201456_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000003049 85.0
DTH2_k127_6342740_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.813e-246 772.0
DTH2_k127_6342740_1 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000001108 191.0
DTH2_k127_6342740_2 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000006392 99.0
DTH2_k127_6352802_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1032.0
DTH2_k127_6358725_0 PFAM Cation K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 486.0
DTH2_k127_6358725_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001959 269.0
DTH2_k127_6358725_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000001499 206.0
DTH2_k127_6358725_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000001403 156.0
DTH2_k127_6369691_0 Domain of unknown function DUF87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 488.0
DTH2_k127_6369691_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 336.0
DTH2_k127_6369834_0 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 551.0
DTH2_k127_6369834_1 - - - - 0.000393 48.0
DTH2_k127_6381367_0 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 424.0
DTH2_k127_6381367_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003924 274.0
DTH2_k127_6381367_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000007434 265.0
DTH2_k127_6381367_3 - - - - 0.0000000000000000000000000000000000000000000000000001107 203.0
DTH2_k127_6381367_4 TIR domain - - - 0.00000000001686 71.0
DTH2_k127_6399248_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 548.0
DTH2_k127_6399248_1 Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 403.0
DTH2_k127_6399248_2 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 353.0
DTH2_k127_6399248_3 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000004068 177.0
DTH2_k127_6399248_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000002081 59.0
DTH2_k127_6408765_0 Involved in cell shape control K22222 - - 1.524e-202 634.0
DTH2_k127_6408765_1 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 506.0
DTH2_k127_6408765_2 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 326.0
DTH2_k127_6408765_3 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007665 288.0
DTH2_k127_6408765_4 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000912 249.0
DTH2_k127_6410753_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 539.0
DTH2_k127_6410753_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000006019 220.0
DTH2_k127_6410786_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 535.0
DTH2_k127_6410786_1 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003744 281.0
DTH2_k127_6410786_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000002911 218.0
DTH2_k127_6410786_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000000000008872 166.0
DTH2_k127_6410786_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000002483 152.0
DTH2_k127_6410786_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000003821 98.0
DTH2_k127_6413735_0 Belongs to the MCM family K10726 - - 6.553e-218 683.0
DTH2_k127_6413735_1 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000005924 143.0
DTH2_k127_6413735_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000001393 70.0
DTH2_k127_6417917_0 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 287.0
DTH2_k127_6417917_1 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000165 166.0
DTH2_k127_6417917_2 Integral membrane protein DUF92 - - - 0.000007822 48.0
DTH2_k127_6425132_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 345.0
DTH2_k127_6425132_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000001173 155.0
DTH2_k127_6425132_2 STAS domain K04749 - - 0.000000000000001063 83.0
DTH2_k127_6438232_0 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 297.0
DTH2_k127_6438232_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382,K00383 - 1.8.1.4,1.8.1.7 0.000000000000007679 76.0
DTH2_k127_6438232_2 - - - - 0.00000000007469 64.0
DTH2_k127_6443509_0 Belongs to the peptidase S16 family - - - 2.274e-296 924.0
DTH2_k127_6465963_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 463.0
DTH2_k127_6465963_1 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 306.0
DTH2_k127_6503891_0 COG1233 Phytoene dehydrogenase and related proteins K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 9.075e-205 648.0
DTH2_k127_6503891_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000002155 212.0
DTH2_k127_6503891_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000001083 191.0
DTH2_k127_6527327_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
DTH2_k127_6527327_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000002926 229.0
DTH2_k127_6527327_2 Rubrerythrin - - - 0.00000000000004815 72.0
DTH2_k127_6562625_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 311.0
DTH2_k127_6562625_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 282.0
DTH2_k127_6584285_0 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
DTH2_k127_6584285_1 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000007125 237.0
DTH2_k127_6584285_2 DEAD DEAH box helicase domain protein K03725 - - 0.0000000000000000000000000000000000006776 154.0
DTH2_k127_6584285_3 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000000000000002701 131.0
DTH2_k127_6585944_0 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 413.0
DTH2_k127_6585944_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 384.0
DTH2_k127_6639179_0 PFAM ABC transporter K00400 - - 6.237e-274 850.0
DTH2_k127_6639179_1 Belongs to the UPF0288 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 510.0
DTH2_k127_6639179_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 412.0
DTH2_k127_6639179_3 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003923 237.0
DTH2_k127_6639179_4 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000007936 189.0
DTH2_k127_6639179_5 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000000000000000003005 190.0
DTH2_k127_6643747_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
DTH2_k127_6643747_1 PFAM PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009223 280.0
DTH2_k127_6643747_2 - - - - 0.000000000000000000000000000000000000009111 151.0
DTH2_k127_6655183_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 6.566e-237 734.0
DTH2_k127_6655183_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 410.0
DTH2_k127_6753126_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 604.0
DTH2_k127_6753126_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000004844 133.0
DTH2_k127_6765558_0 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
DTH2_k127_6765558_1 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000001133 105.0
DTH2_k127_6765558_2 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000002722 103.0
DTH2_k127_6765558_3 - - - - 0.000000000001177 72.0
DTH2_k127_6803259_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 313.0
DTH2_k127_6803259_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000001273 233.0
DTH2_k127_6803259_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000003712 226.0
DTH2_k127_6803259_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000002319 182.0
DTH2_k127_6803259_4 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.000000000000000000000000000000000000003242 149.0
DTH2_k127_6803259_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000000000173 110.0
DTH2_k127_6803259_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000004427 108.0
DTH2_k127_6803259_7 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.00000000000000000000002592 100.0
DTH2_k127_6803259_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000005135 99.0
DTH2_k127_6805531_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 353.0
DTH2_k127_6805531_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000002383 220.0
DTH2_k127_6805531_2 - - - - 0.000000000000000000000000000001434 123.0
DTH2_k127_6805531_3 Protein of unknown function (DUF473) K09135 - - 0.0000000000000000000000000005258 118.0
DTH2_k127_6811700_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 454.0
DTH2_k127_6811700_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
DTH2_k127_6811700_2 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000004962 72.0
DTH2_k127_6901027_0 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 355.0
DTH2_k127_6901027_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008454 283.0
DTH2_k127_6901027_2 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 251.0
DTH2_k127_6901027_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000418 123.0
DTH2_k127_6979156_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 580.0
DTH2_k127_6979156_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 379.0
DTH2_k127_6979156_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 370.0
DTH2_k127_6979156_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 346.0
DTH2_k127_6979156_4 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 311.0
DTH2_k127_6979156_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000364 248.0
DTH2_k127_6979156_6 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006534 241.0
DTH2_k127_6979156_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000009527 123.0
DTH2_k127_6979156_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000005826 93.0
DTH2_k127_6980391_0 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 301.0
DTH2_k127_6980391_1 HEAT repeat - - - 0.00000000000000000000000004013 119.0
DTH2_k127_6980391_2 HEAT repeat - - - 0.0000000000000000000000001713 116.0
DTH2_k127_7057926_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
DTH2_k127_7057926_1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 290.0
DTH2_k127_7057926_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000001798 226.0
DTH2_k127_7057926_3 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002329 60.0
DTH2_k127_7065326_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 473.0
DTH2_k127_7215912_0 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 417.0
DTH2_k127_7215912_1 in RNase L inhibitor, RLI K06174 - - 0.00000000000000000000000000000000000000000000005622 170.0
DTH2_k127_7215912_2 RNase L inhibitor, RLI - - - 0.000000000000000000000004822 108.0
DTH2_k127_735876_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 482.0
DTH2_k127_735876_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 475.0
DTH2_k127_735876_2 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
DTH2_k127_735876_3 PFAM peptidase zinc-dependent K06974 - - 0.000000000000000000000000000000000000000000000000000002097 199.0
DTH2_k127_735876_4 Belongs to the UPF0146 family K09713 - - 0.0000000000000000000000000000000000000000000279 173.0
DTH2_k127_735876_5 transcription factor (CBF NF-Y) - - - 0.0000000000000000000000000009839 112.0
DTH2_k127_7598216_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 612.0
DTH2_k127_7598216_1 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 396.0
DTH2_k127_7598216_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000005965 175.0
DTH2_k127_7624183_0 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 521.0
DTH2_k127_7624183_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 312.0
DTH2_k127_7624183_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000232 67.0
DTH2_k127_7624183_3 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000002534 68.0
DTH2_k127_7647532_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 9.806e-201 634.0
DTH2_k127_7647532_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000007846 64.0
DTH2_k127_7647532_2 Helix-turn-helix domain protein K03627 - - 0.0000003267 55.0
DTH2_k127_7680555_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 480.0
DTH2_k127_7680555_1 - K03686 - - 0.0000000000000000000003886 96.0
DTH2_k127_7680555_2 - - - - 0.00000006968 57.0
DTH2_k127_7681852_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 382.0
DTH2_k127_7681852_1 PFAM response regulator receiver K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 368.0
DTH2_k127_7693306_0 TGS domain protein K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
DTH2_k127_7693306_1 - - - - 0.00000000000000000000000000000000000000009729 155.0
DTH2_k127_7693306_2 - - - - 0.00000003535 57.0
DTH2_k127_7701312_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
DTH2_k127_7701312_1 YCII-related domain - - - 0.00000000000000000000001312 104.0
DTH2_k127_7701312_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000001301 61.0
DTH2_k127_7707825_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 424.0
DTH2_k127_7707825_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 304.0
DTH2_k127_7707825_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000004378 56.0
DTH2_k127_7724318_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 347.0
DTH2_k127_7724318_1 PFAM ferredoxin-dependent glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000009429 208.0
DTH2_k127_7732842_0 RimK domain protein ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 379.0
DTH2_k127_7732842_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 331.0
DTH2_k127_7732842_2 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000006682 213.0
DTH2_k127_7825344_0 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 372.0
DTH2_k127_7825344_1 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000006808 210.0
DTH2_k127_7825344_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000004896 175.0
DTH2_k127_7825344_3 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000008311 109.0
DTH2_k127_7828153_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007068 278.0
DTH2_k127_7828153_1 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000006983 142.0
DTH2_k127_7828153_2 integral membrane protein - - - 0.0000000000000000000000000003061 117.0
DTH2_k127_7828153_3 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000008915 74.0
DTH2_k127_7845738_0 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 372.0
DTH2_k127_7845738_1 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000005979 192.0
DTH2_k127_7845738_2 - - - - 0.00000000000000000000000000001026 128.0
DTH2_k127_784784_0 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 391.0
DTH2_k127_784784_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
DTH2_k127_784784_2 PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 315.0
DTH2_k127_784784_3 Molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000005032 156.0
DTH2_k127_784784_4 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000000000000000008282 129.0
DTH2_k127_784784_5 Transcriptional regulator K07108 - - 0.0000000000000000000000000000000233 133.0
DTH2_k127_7889854_0 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
DTH2_k127_7889854_1 PFAM Yip1 domain - - - 0.00000000000000000000000002309 118.0
DTH2_k127_7889854_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000006585 82.0
DTH2_k127_7899903_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 598.0
DTH2_k127_7899903_1 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000001436 138.0
DTH2_k127_7899903_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000003384 139.0
DTH2_k127_7899903_3 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000001611 128.0
DTH2_k127_7922173_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001281 254.0
DTH2_k127_7922173_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000001029 218.0
DTH2_k127_7922173_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000000000001333 196.0
DTH2_k127_7922173_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000000000002735 128.0
DTH2_k127_7922173_4 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000003612 131.0
DTH2_k127_7922173_5 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000000001374 120.0
DTH2_k127_7922173_6 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000001596 89.0
DTH2_k127_8002183_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 494.0
DTH2_k127_8002183_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 374.0
DTH2_k127_8002183_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001899 244.0
DTH2_k127_8002183_3 Belongs to the UPF0212 family K09731 - - 0.0000000000000000000000000000000000000000000000002454 177.0
DTH2_k127_8002183_4 Family of unknown function (DUF5350) - - - 0.00000000000000000000001062 103.0
DTH2_k127_8023581_0 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000102 181.0
DTH2_k127_8023581_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000008315 169.0
DTH2_k127_8023581_2 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.00000000000000000000000000000000000000002137 165.0
DTH2_k127_80638_0 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
DTH2_k127_80638_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 298.0
DTH2_k127_80638_2 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.000000000000000000005986 93.0
DTH2_k127_8072978_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 602.0
DTH2_k127_8072978_1 phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 546.0
DTH2_k127_8072978_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
DTH2_k127_8094278_0 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 340.0
DTH2_k127_8094278_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 327.0
DTH2_k127_8094278_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000001544 109.0
DTH2_k127_8094278_3 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000005943 91.0
DTH2_k127_8105514_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000005775 204.0
DTH2_k127_8167571_0 PFAM type II secretion system protein E K07332 - - 1.595e-285 887.0
DTH2_k127_8167571_1 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
DTH2_k127_8181184_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 2.073e-195 615.0
DTH2_k127_8181184_1 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 451.0
DTH2_k127_8181184_2 Small multi-drug export protein - - - 0.0000000000000000000000000000000000000008114 156.0
DTH2_k127_8181184_3 Secreted repeat of unknown function - - - 0.0000000000000000000000000000007414 128.0
DTH2_k127_8221898_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 512.0
DTH2_k127_8221898_1 Protein of unknown function (DUF2953) - - - 0.000000000000072 78.0
DTH2_k127_8277827_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 594.0
DTH2_k127_8277827_1 Chromate transporter K07240 - - 0.000000000000000000000007798 107.0
DTH2_k127_8290254_0 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 574.0
DTH2_k127_8290254_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 511.0
DTH2_k127_8290254_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
DTH2_k127_8290254_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
DTH2_k127_8290254_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000008343 208.0
DTH2_k127_8290254_5 Protein of unknown function (DUF432) K09149 - - 0.00000000000000000000000000000000000000000000000000111 192.0
DTH2_k127_8290254_6 - - - - 0.0000000000001684 73.0
DTH2_k127_8387760_0 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002708 281.0
DTH2_k127_8387760_1 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000007164 211.0
DTH2_k127_8387760_2 DNA polymerase activity K02319 - 2.7.7.7 0.000000000000000000000000000000000191 141.0
DTH2_k127_8387760_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000989 92.0
DTH2_k127_8387760_4 - - - - 0.000000000005262 75.0
DTH2_k127_8469605_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 458.0
DTH2_k127_8469605_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 389.0
DTH2_k127_8469605_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001005 276.0
DTH2_k127_8469605_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000008462 238.0
DTH2_k127_8469605_4 - K06193 - - 0.0000000000006261 70.0
DTH2_k127_8501268_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 312.0
DTH2_k127_8535230_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 433.0
DTH2_k127_8535230_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 441.0
DTH2_k127_8535230_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 417.0
DTH2_k127_8535230_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000001592 211.0
DTH2_k127_8862224_0 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 379.0
DTH2_k127_8862224_1 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000002117 198.0
DTH2_k127_8869427_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 531.0
DTH2_k127_8869427_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 485.0
DTH2_k127_8876642_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 1.578e-262 815.0
DTH2_k127_8876642_1 PFAM Radical SAM domain protein K06937 - - 2.194e-236 739.0
DTH2_k127_8876642_10 - - - - 0.0000000000000000000000219 102.0
DTH2_k127_8876642_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000005933 92.0
DTH2_k127_8876642_2 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 569.0
DTH2_k127_8876642_3 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 428.0
DTH2_k127_8876642_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 419.0
DTH2_k127_8876642_5 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 375.0
DTH2_k127_8876642_6 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 282.0
DTH2_k127_8876642_7 TIGRFAM Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000001745 234.0
DTH2_k127_8876642_8 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000003021 197.0
DTH2_k127_8876642_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000664 173.0
DTH2_k127_8876734_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 269.0
DTH2_k127_8876734_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
DTH2_k127_8876734_2 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000000000000000000000000000145 203.0
DTH2_k127_8876734_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000001802 127.0
DTH2_k127_8916621_0 acid binding OB-fold tRNA helicase-type K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 437.0
DTH2_k127_8916621_1 - - - - 0.0000000000000000000000000000000000003487 142.0
DTH2_k127_8916621_2 - - - - 0.00000000000000000000000000004855 124.0
DTH2_k127_8916621_3 - - - - 0.0000000000000000004187 88.0
DTH2_k127_8923123_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 528.0
DTH2_k127_8923123_1 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004694 279.0
DTH2_k127_8941791_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 596.0
DTH2_k127_8941791_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001066 244.0
DTH2_k127_8941791_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000003999 182.0
DTH2_k127_8941791_3 Domain of unknown function DUF123 - - - 0.000000002917 60.0
DTH2_k127_8962972_0 involved in cell wall biogenesis K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 443.0
DTH2_k127_8962972_1 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000007505 160.0
DTH2_k127_8970851_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 597.0
DTH2_k127_8970851_1 Protein of unknown function (DUF1648) - - - 0.000004066 54.0
DTH2_k127_8979728_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
DTH2_k127_8979728_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 361.0
DTH2_k127_8979728_2 - - - - 0.00002496 49.0
DTH2_k127_9028064_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 503.0
DTH2_k127_9028064_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 460.0
DTH2_k127_9028064_2 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 342.0
DTH2_k127_9028064_3 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000005655 235.0
DTH2_k127_9028159_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 8.061e-201 631.0
DTH2_k127_9028159_1 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000008347 253.0
DTH2_k127_9042332_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 534.0
DTH2_k127_9042332_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000005814 118.0
DTH2_k127_9069770_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 475.0
DTH2_k127_9069770_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000006919 121.0
DTH2_k127_9069770_2 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000002547 117.0
DTH2_k127_9069770_3 Histidine kinase-like ATPase domain - - - 0.000000000000000004177 89.0
DTH2_k127_9069770_4 STAS domain K04749 - - 0.0006689 46.0
DTH2_k127_9110936_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000002229 231.0
DTH2_k127_9110936_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000003683 198.0
DTH2_k127_9110936_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
DTH2_k127_9110936_3 Belongs to the UPF0305 family - - - 0.0000000000000000000000000000000000000000001335 164.0
DTH2_k127_9127943_0 PFAM SufBD protein K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 555.0
DTH2_k127_9127943_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
DTH2_k127_9127943_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000002336 97.0
DTH2_k127_9206018_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 592.0
DTH2_k127_9206018_1 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 422.0
DTH2_k127_9206018_2 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 405.0
DTH2_k127_9206018_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 384.0
DTH2_k127_9206018_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000000002248 94.0
DTH2_k127_9211275_0 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000002182 210.0
DTH2_k127_9211275_1 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000005574 139.0
DTH2_k127_9211275_2 Nucleotidyltransferase domain K07076 - - 0.000000000000000000003711 98.0
DTH2_k127_9211275_3 Protein of unknown function DUF86 - - - 0.0000003018 56.0
DTH2_k127_9225381_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000001738 244.0
DTH2_k127_9225381_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000009009 194.0
DTH2_k127_9225381_2 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000003342 117.0
DTH2_k127_9248495_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000007132 164.0
DTH2_k127_9248495_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000006356 100.0
DTH2_k127_9248495_3 - - - - 0.00005527 51.0
DTH2_k127_9306384_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007367 252.0
DTH2_k127_9306384_1 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000003282 192.0
DTH2_k127_9306384_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000004129 112.0
DTH2_k127_9306384_3 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.0000000000000007332 81.0
DTH2_k127_9341433_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000002456 165.0
DTH2_k127_9341433_1 ABC transporter K01995 - - 0.000000000000000000000000001487 113.0
DTH2_k127_9392652_0 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 512.0
DTH2_k127_9392652_1 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002155 256.0
DTH2_k127_9418158_0 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 379.0
DTH2_k127_9418158_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000001252 134.0
DTH2_k127_9567862_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 290.0
DTH2_k127_9567862_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
DTH2_k127_9576193_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 578.0
DTH2_k127_9576193_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 370.0
DTH2_k127_9576193_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000000000003193 121.0
DTH2_k127_9576193_11 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000007664 110.0
DTH2_k127_9576193_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000000007243 93.0
DTH2_k127_9576193_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 346.0
DTH2_k127_9576193_3 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 342.0
DTH2_k127_9576193_4 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008576 241.0
DTH2_k127_9576193_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
DTH2_k127_9576193_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
DTH2_k127_9576193_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000001049 198.0
DTH2_k127_9576193_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000002998 199.0
DTH2_k127_9576193_9 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000003008 167.0
DTH2_k127_9843919_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 471.0
DTH2_k127_9843919_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 373.0
DTH2_k127_9843919_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 333.0
DTH2_k127_9843919_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000000000000009199 214.0
DTH2_k127_9843919_4 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000009066 186.0
DTH2_k127_9843919_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000001076 198.0
DTH2_k127_9843919_6 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000008771 152.0
DTH2_k127_9843919_7 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000000003074 126.0
DTH2_k127_9945400_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 1.454e-220 698.0
DTH2_k127_9945400_1 MoeA N-terminal region (domain I and II) - - - 0.000000000000000000000000000000006798 132.0