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Overview

ID MAG01629
Name HFD2_bin.1
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Bryobacterales
Family Bryobacteraceae
Genus Palsa-187
Species
Assembly information
Completeness (%) 67.67
Contamination (%) 0.14
GC content (%) 61.0
N50 (bp) 10,878
Genome size (bp) 3,730,842

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3440

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1019017_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1069.0
HFD2_k127_1019017_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 465.0
HFD2_k127_1019017_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 452.0
HFD2_k127_1019017_4 Dehydrogenase K00117 - 1.1.5.2 0.0000000000001755 76.0
HFD2_k127_1021689_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.566e-200 631.0
HFD2_k127_1021689_1 PFAM Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 589.0
HFD2_k127_1021689_2 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 540.0
HFD2_k127_1021689_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 375.0
HFD2_k127_1054696_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 486.0
HFD2_k127_1054696_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 409.0
HFD2_k127_1054696_2 Glycosyltransferase like family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 316.0
HFD2_k127_1054696_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 299.0
HFD2_k127_1054696_4 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000009976 171.0
HFD2_k127_1054696_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000004332 154.0
HFD2_k127_1054696_7 GHMP kinase domain protein K07031 - 2.7.1.168 0.000000000000000000000000007136 111.0
HFD2_k127_1054696_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000003019 70.0
HFD2_k127_1076665_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 3.289e-232 727.0
HFD2_k127_1076665_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.151e-225 725.0
HFD2_k127_1076665_10 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000004323 162.0
HFD2_k127_1076665_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000007611 164.0
HFD2_k127_1076665_12 - - - - 0.00000000000000000000000000000000003685 145.0
HFD2_k127_1076665_13 HDOD domain - - - 0.0000000000000000000000003783 115.0
HFD2_k127_1076665_14 BON domain - - - 0.00000000000000000000000465 108.0
HFD2_k127_1076665_15 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000006442 103.0
HFD2_k127_1076665_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000178 99.0
HFD2_k127_1076665_17 - - - - 0.00000000001374 70.0
HFD2_k127_1076665_19 YtxH-like protein - - - 0.000005305 53.0
HFD2_k127_1076665_2 Aminotransferase class I and II - - - 2.576e-194 615.0
HFD2_k127_1076665_3 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 485.0
HFD2_k127_1076665_4 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 459.0
HFD2_k127_1076665_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 442.0
HFD2_k127_1076665_6 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 371.0
HFD2_k127_1076665_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
HFD2_k127_1076665_9 - - - - 0.0000000000000000000000000000000000000000001198 165.0
HFD2_k127_1090907_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1528.0
HFD2_k127_1090907_1 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00124,K18005 - 1.12.1.2 3.185e-248 775.0
HFD2_k127_1090907_2 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001308 273.0
HFD2_k127_1090907_3 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003523 234.0
HFD2_k127_1090907_4 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.000000000000000000000000000000000000000000000000000000005879 202.0
HFD2_k127_1090907_5 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000007651 148.0
HFD2_k127_1090907_6 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000916 83.0
HFD2_k127_1090907_7 Protein of unknown function (DUF3011) - - - 0.00000000000001196 85.0
HFD2_k127_1090907_8 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000003836 68.0
HFD2_k127_1099130_0 response regulator - - - 3.08e-219 687.0
HFD2_k127_1099130_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 574.0
HFD2_k127_1099130_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 555.0
HFD2_k127_1099130_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
HFD2_k127_1099130_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000761 282.0
HFD2_k127_1099130_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
HFD2_k127_1099130_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000001757 138.0
HFD2_k127_1099130_7 - - - - 0.00001142 56.0
HFD2_k127_1103249_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.282e-276 861.0
HFD2_k127_1103249_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 472.0
HFD2_k127_1103249_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 453.0
HFD2_k127_1103249_3 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 325.0
HFD2_k127_1103249_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002737 263.0
HFD2_k127_1103249_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000002264 209.0
HFD2_k127_1103249_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000003351 199.0
HFD2_k127_1103249_7 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000003521 172.0
HFD2_k127_1103249_8 Heavy-metal resistance - - - 0.000000000000000000000000000000001565 136.0
HFD2_k127_1103249_9 RNA recognition motif - - - 0.000000000000000000000000000000002376 134.0
HFD2_k127_110607_0 - K17285 - - 4.516e-314 983.0
HFD2_k127_110607_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 517.0
HFD2_k127_110607_10 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00004104 57.0
HFD2_k127_110607_2 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 483.0
HFD2_k127_110607_3 Collagenase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 374.0
HFD2_k127_110607_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 323.0
HFD2_k127_110607_5 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000006798 230.0
HFD2_k127_110607_6 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0000000000000000000000000000000000000002946 160.0
HFD2_k127_110607_7 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000000000000007735 130.0
HFD2_k127_110607_8 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000003787 106.0
HFD2_k127_110607_9 PFAM Sulfate transporter antisigma-factor antagonist STAS K06378 - - 0.0000000006554 65.0
HFD2_k127_1112123_0 Bacterial protein of unknown function (DUF839) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 542.0
HFD2_k127_1112123_1 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 512.0
HFD2_k127_1112123_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 260.0
HFD2_k127_1112123_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 250.0
HFD2_k127_1112123_4 PFAM Survival protein SurE K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
HFD2_k127_1112123_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
HFD2_k127_1112123_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000001602 95.0
HFD2_k127_1112123_7 Amidohydrolase family - - - 0.000003532 55.0
HFD2_k127_1119715_0 NeuB family K01654 - 2.5.1.56 2.5e-244 770.0
HFD2_k127_1119715_1 GHMP kinases C terminal K07031 - 2.7.1.168 1.393e-194 618.0
HFD2_k127_1119715_2 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 441.0
HFD2_k127_1119715_3 Nucleotidyl transferase K15669 - 2.7.7.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 287.0
HFD2_k127_1119715_4 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000454 176.0
HFD2_k127_1119715_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000004511 70.0
HFD2_k127_1126937_0 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 500.0
HFD2_k127_1126937_1 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 434.0
HFD2_k127_1126937_2 - - - - 0.00000000000000000000000000000000000000000002011 171.0
HFD2_k127_1126937_3 cellulose binding - - - 0.0000000000000000000000002218 110.0
HFD2_k127_114111_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 565.0
HFD2_k127_114111_1 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000000003101 209.0
HFD2_k127_114111_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000006015 156.0
HFD2_k127_1150461_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1398.0
HFD2_k127_1150461_1 Reductase C-terminal K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
HFD2_k127_1150461_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 386.0
HFD2_k127_1150461_3 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 326.0
HFD2_k127_1150461_4 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000003409 192.0
HFD2_k127_1150461_5 AAA domain K01090 - 3.1.3.16 0.000000000000000000000000000000000000000000003049 171.0
HFD2_k127_1150461_6 Ferredoxin K04755 - - 0.00000000000000000000000000000000000002442 145.0
HFD2_k127_1150461_7 energy transducer activity K03832 - - 0.0000000000000000000007678 101.0
HFD2_k127_1157430_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1239.0
HFD2_k127_1157430_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 564.0
HFD2_k127_1157430_10 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 384.0
HFD2_k127_1157430_11 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001332 271.0
HFD2_k127_1157430_12 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000000000000000000000001658 206.0
HFD2_k127_1157430_13 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000002892 145.0
HFD2_k127_1157430_14 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000007783 78.0
HFD2_k127_1157430_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 548.0
HFD2_k127_1157430_3 AMP-binding enzyme C-terminal domain K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 544.0
HFD2_k127_1157430_4 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 544.0
HFD2_k127_1157430_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 504.0
HFD2_k127_1157430_6 Domain of unknown function (DUF1972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 496.0
HFD2_k127_1157430_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 466.0
HFD2_k127_1157430_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 417.0
HFD2_k127_1157430_9 MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 419.0
HFD2_k127_1168369_0 COG2303 Choline dehydrogenase and related flavoproteins K06151 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 471.0
HFD2_k127_1168369_1 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.0000000000000005129 80.0
HFD2_k127_1175738_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 363.0
HFD2_k127_1175738_1 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 314.0
HFD2_k127_1175738_2 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 306.0
HFD2_k127_1175738_3 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000004185 201.0
HFD2_k127_1175738_4 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000005408 208.0
HFD2_k127_1175738_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000001059 155.0
HFD2_k127_1209816_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.375e-320 986.0
HFD2_k127_1209816_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 611.0
HFD2_k127_1209816_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000001291 113.0
HFD2_k127_1209816_2 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 430.0
HFD2_k127_1209816_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 308.0
HFD2_k127_1209816_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001198 254.0
HFD2_k127_1209816_5 - K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 259.0
HFD2_k127_1209816_6 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000000000000000000000000000001876 209.0
HFD2_k127_1209816_7 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000005036 188.0
HFD2_k127_1209816_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000002556 185.0
HFD2_k127_1209816_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000003535 154.0
HFD2_k127_1214400_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 439.0
HFD2_k127_1214400_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 325.0
HFD2_k127_1214400_2 - - - - 0.000000000000000000000000002065 121.0
HFD2_k127_1214400_3 - - - - 0.00000000000000000000000001408 121.0
HFD2_k127_1214400_4 - - - - 0.00000000000000000000008403 108.0
HFD2_k127_1214400_5 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0004277 52.0
HFD2_k127_1251528_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 6.935e-231 739.0
HFD2_k127_1251528_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 299.0
HFD2_k127_1251528_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000002467 195.0
HFD2_k127_12605_0 PQQ enzyme repeat K00114 - 1.1.2.8 1.306e-198 633.0
HFD2_k127_12605_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002293 216.0
HFD2_k127_12605_2 PQQ enzyme repeat - - - 0.00001271 50.0
HFD2_k127_1262036_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 307.0
HFD2_k127_1262036_1 COG2346, Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000006574 149.0
HFD2_k127_1262036_2 - - - - 0.00000000000000000000000000000004871 142.0
HFD2_k127_1262036_3 - - - - 0.0000000000000000000000000000002278 134.0
HFD2_k127_1262036_4 - - - - 0.000000000000000000000000002399 121.0
HFD2_k127_1262036_5 - - - - 0.0000000000000000000000001219 117.0
HFD2_k127_1262036_6 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.000000000000000162 81.0
HFD2_k127_1262036_7 - - - - 0.00002366 50.0
HFD2_k127_1265307_0 Domain of unknown function (DUF5107) - - - 0.00000000000000000000000000002635 134.0
HFD2_k127_1265307_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001066 61.0
HFD2_k127_1269309_0 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003922 220.0
HFD2_k127_1269309_1 Choline/ethanolamine kinase K09965 - - 0.00000000000000000000000000000000000000000000000000000000000183 211.0
HFD2_k127_1269309_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000000000000000000007458 210.0
HFD2_k127_1269309_3 Histidine kinase - - - 0.0000000000000000000000000000000000000002805 164.0
HFD2_k127_1273206_0 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 540.0
HFD2_k127_1273206_1 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 387.0
HFD2_k127_1273206_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000004881 206.0
HFD2_k127_1273206_3 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000001652 212.0
HFD2_k127_128269_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1381.0
HFD2_k127_128269_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 351.0
HFD2_k127_128269_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
HFD2_k127_128269_3 peptidase inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000009487 193.0
HFD2_k127_128269_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000003325 206.0
HFD2_k127_128269_5 Peptidase MA superfamily - - - 0.00000000000000000000381 106.0
HFD2_k127_128269_7 electron transfer activity - - - 0.0000002969 55.0
HFD2_k127_1287596_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.417e-292 904.0
HFD2_k127_1287596_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 1.884e-288 900.0
HFD2_k127_1287596_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 488.0
HFD2_k127_1287596_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 478.0
HFD2_k127_1287596_12 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 456.0
HFD2_k127_1287596_13 PFAM Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 437.0
HFD2_k127_1287596_14 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 399.0
HFD2_k127_1287596_15 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 406.0
HFD2_k127_1287596_16 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000002467 258.0
HFD2_k127_1287596_17 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000711 171.0
HFD2_k127_1287596_18 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000000000005784 148.0
HFD2_k127_1287596_2 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 7.075e-281 881.0
HFD2_k127_1287596_20 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000001193 96.0
HFD2_k127_1287596_3 MacB-like periplasmic core domain - - - 3.642e-258 822.0
HFD2_k127_1287596_4 MacB-like periplasmic core domain - - - 1.274e-228 736.0
HFD2_k127_1287596_5 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 556.0
HFD2_k127_1287596_6 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 521.0
HFD2_k127_1287596_7 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 491.0
HFD2_k127_1287596_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 494.0
HFD2_k127_1287596_9 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 485.0
HFD2_k127_1314916_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1155.0
HFD2_k127_1314916_1 Amino acid kinase family K00928 - 2.7.2.4 8.706e-196 626.0
HFD2_k127_1314916_2 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 407.0
HFD2_k127_1314916_3 transmembrane transporter activity K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 318.0
HFD2_k127_1314916_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002417 289.0
HFD2_k127_1314916_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
HFD2_k127_1314916_6 - - - - 0.00000000000000000000000005182 119.0
HFD2_k127_1314916_7 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000418 53.0
HFD2_k127_1318256_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
HFD2_k127_1318256_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002081 264.0
HFD2_k127_1318256_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000002477 142.0
HFD2_k127_1318256_3 acr, cog1565 - - - 0.0000000000000002073 93.0
HFD2_k127_1318256_4 Formiminotransferase-cyclodeaminase K01746,K13990 - 2.1.2.5,4.3.1.4 0.000002095 56.0
HFD2_k127_1318256_5 - - - - 0.00001869 55.0
HFD2_k127_1326738_0 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000000000000000000000000000000000000000000005874 232.0
HFD2_k127_1326738_1 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000004294 104.0
HFD2_k127_1326738_2 Belongs to the 'phage' integrase family - - - 0.00000000008138 63.0
HFD2_k127_1327536_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 4.728e-195 617.0
HFD2_k127_1327536_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 464.0
HFD2_k127_1327536_2 efflux protein, MATE family K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 415.0
HFD2_k127_1327536_3 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000000000000001776 218.0
HFD2_k127_1327536_4 - - - - 0.0004482 48.0
HFD2_k127_1338723_0 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 2.769e-262 825.0
HFD2_k127_1338723_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 2.837e-196 619.0
HFD2_k127_1338723_10 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000006125 183.0
HFD2_k127_1338723_11 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000009103 162.0
HFD2_k127_1338723_12 Putative peptidoglycan binding domain - - - 0.00000000000000000002014 98.0
HFD2_k127_1338723_2 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 606.0
HFD2_k127_1338723_3 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 490.0
HFD2_k127_1338723_4 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
HFD2_k127_1338723_5 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 420.0
HFD2_k127_1338723_6 AAA domain K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 364.0
HFD2_k127_1338723_7 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007596 287.0
HFD2_k127_1338723_8 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
HFD2_k127_1338723_9 EVE domain - - - 0.0000000000000000000000000000000000000000000000000009484 186.0
HFD2_k127_134734_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.292e-205 658.0
HFD2_k127_134734_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 487.0
HFD2_k127_134734_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006752 271.0
HFD2_k127_134734_3 metal cluster binding - - - 0.00000000000000000000000000000000000000002501 161.0
HFD2_k127_134734_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000001257 87.0
HFD2_k127_134734_5 Peptidase M56 - - - 0.0000000000000369 72.0
HFD2_k127_134734_6 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0000000000264 75.0
HFD2_k127_1368477_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 592.0
HFD2_k127_1373157_0 PQQ-like domain K00117 - 1.1.5.2 1.721e-203 651.0
HFD2_k127_1373157_1 PQQ-like domain K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 500.0
HFD2_k127_1373157_2 Pas domain - - - 0.00000000000000000000000000000000001672 139.0
HFD2_k127_1373157_3 Copper binding periplasmic protein CusF K07152 - - 0.000002636 53.0
HFD2_k127_137681_0 integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 327.0
HFD2_k127_137681_1 IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 316.0
HFD2_k127_137681_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000171 48.0
HFD2_k127_1382307_0 ABC transporter transmembrane K11085 - - 1.099e-264 829.0
HFD2_k127_1382307_1 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 520.0
HFD2_k127_1382307_10 Helix-turn-helix domain K15539 - - 0.0000000000000000000000002643 116.0
HFD2_k127_1382307_11 PFAM YcfA family protein - - - 0.0000000000000000000000005878 104.0
HFD2_k127_1382307_2 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 423.0
HFD2_k127_1382307_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 370.0
HFD2_k127_1382307_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 294.0
HFD2_k127_1382307_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004464 279.0
HFD2_k127_1382307_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000002348 243.0
HFD2_k127_1382307_7 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000002422 153.0
HFD2_k127_1382307_8 - - - - 0.0000000000000000000000000000005892 128.0
HFD2_k127_1382307_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000002062 118.0
HFD2_k127_1433361_0 PFAM NAD(P)H dehydrogenase (quinone) K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 291.0
HFD2_k127_1433361_1 B12 binding domain - - - 0.00000000000000000000000001707 109.0
HFD2_k127_1433361_2 - K07484 - - 0.0000000006523 62.0
HFD2_k127_1433361_3 Peptidase M56 - - - 0.00000001359 61.0
HFD2_k127_146127_0 - - - - 0.000000000000000000000000000000000000000000000000000000000002088 226.0
HFD2_k127_146127_1 Carboxypeptidase regulatory-like domain - - - 0.000002005 58.0
HFD2_k127_1468332_0 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000001252 243.0
HFD2_k127_1468332_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000036 240.0
HFD2_k127_1468332_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000005506 175.0
HFD2_k127_1468332_3 PIN domain - - - 0.00000002337 61.0
HFD2_k127_1493093_0 putrescine transport K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 371.0
HFD2_k127_1493093_1 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
HFD2_k127_1493093_2 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004271 270.0
HFD2_k127_1493093_3 TOBE domain K11072 - 3.6.3.31 0.00000000000000000003485 93.0
HFD2_k127_1531982_0 Amidohydrolase family - - - 3.415e-234 734.0
HFD2_k127_153713_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007552 282.0
HFD2_k127_153713_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
HFD2_k127_1564876_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HFD2_k127_1564876_1 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
HFD2_k127_1564876_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000007045 135.0
HFD2_k127_1564876_3 TIGRFAM TonB family K03832 - - 0.00000000000000000003702 99.0
HFD2_k127_1598395_0 AcrB/AcrD/AcrF family K03296 - - 2.673e-273 857.0
HFD2_k127_1598395_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 409.0
HFD2_k127_1598395_2 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 421.0
HFD2_k127_1598395_3 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002295 276.0
HFD2_k127_1650791_0 Chase2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 500.0
HFD2_k127_1650791_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 265.0
HFD2_k127_167030_0 TonB-dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 478.0
HFD2_k127_167030_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 409.0
HFD2_k127_167030_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001579 266.0
HFD2_k127_167030_3 - - - - 0.00000000000000000000000000000000000000000001274 165.0
HFD2_k127_167030_4 - - - - 0.00000000000000000000000000000000004702 141.0
HFD2_k127_167030_5 - - - - 0.0000000000000000000000000000000008543 145.0
HFD2_k127_1711259_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 540.0
HFD2_k127_1711259_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 453.0
HFD2_k127_1711259_10 NMT1-like family K02051 - - 0.00000000000006685 83.0
HFD2_k127_1711259_12 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.000002257 59.0
HFD2_k127_1711259_2 PFAM RNA polymerase sigma factor 54, interaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 482.0
HFD2_k127_1711259_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 445.0
HFD2_k127_1711259_4 Dehydrogenase K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 338.0
HFD2_k127_1711259_5 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000001022 227.0
HFD2_k127_1711259_7 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000002683 208.0
HFD2_k127_1711259_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000006728 179.0
HFD2_k127_1711259_9 WxcM-like, C-terminal - - - 0.0000000000000000000000000000003918 130.0
HFD2_k127_1774292_0 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 368.0
HFD2_k127_1774292_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000725 174.0
HFD2_k127_1774292_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000002556 121.0
HFD2_k127_1774292_3 Domain of unknown function (DUF1844) - - - 0.000000000000000000000001469 108.0
HFD2_k127_1779014_0 PFAM Beta-lactamase K18988 - 3.4.16.4 9.032e-207 652.0
HFD2_k127_1779014_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 581.0
HFD2_k127_1779014_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009036 232.0
HFD2_k127_1779014_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000004759 181.0
HFD2_k127_1779014_4 YtkA-like - - - 0.00001084 52.0
HFD2_k127_178085_0 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 616.0
HFD2_k127_178085_1 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 554.0
HFD2_k127_178085_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000002592 127.0
HFD2_k127_178085_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000003498 94.0
HFD2_k127_178085_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000001475 90.0
HFD2_k127_178085_5 Copper binding periplasmic protein CusF K07152 - - 0.0000001267 58.0
HFD2_k127_1790478_0 PFAM FAD linked oxidase - - - 9.738e-202 633.0
HFD2_k127_1790478_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
HFD2_k127_1794928_0 Collagenase K08303 - - 0.0 1088.0
HFD2_k127_1794928_1 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 343.0
HFD2_k127_1794928_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 330.0
HFD2_k127_1794928_3 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 319.0
HFD2_k127_1794928_4 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004531 256.0
HFD2_k127_1794928_5 Subtilase family K01342,K13275 - 3.4.21.62 0.000000000000000000000000000000002339 146.0
HFD2_k127_1794928_6 YCII-related domain - - - 0.00000000000000000000000006021 111.0
HFD2_k127_1794928_7 Domain of unknown function (DUF4136) - - - 0.0000000000000009194 83.0
HFD2_k127_1813037_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 2.215e-263 823.0
HFD2_k127_1813037_1 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 396.0
HFD2_k127_1813037_2 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 314.0
HFD2_k127_1813037_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000468 288.0
HFD2_k127_1813037_4 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000211 214.0
HFD2_k127_1813037_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000001329 193.0
HFD2_k127_1813037_6 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000001484 159.0
HFD2_k127_1813037_7 - - - - 0.00000000000000001448 94.0
HFD2_k127_1813037_8 - - - - 0.0000000008487 66.0
HFD2_k127_1813037_9 alpha/beta hydrolase fold - - - 0.000002395 51.0
HFD2_k127_1853520_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.186e-198 624.0
HFD2_k127_1853520_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 599.0
HFD2_k127_1853520_10 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000002852 96.0
HFD2_k127_1853520_12 Flp Fap pilin component K02651 - - 0.0003521 45.0
HFD2_k127_1853520_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 466.0
HFD2_k127_1853520_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 382.0
HFD2_k127_1853520_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000001039 248.0
HFD2_k127_1853520_6 - K21449 - - 0.000000000000000000000000000000000000000000000000009629 188.0
HFD2_k127_1853520_7 - - - - 0.000000000000000000000000000000000000000000003109 170.0
HFD2_k127_1853520_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000001063 131.0
HFD2_k127_1853520_9 - - - - 0.000000000000000000002276 97.0
HFD2_k127_1871276_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 482.0
HFD2_k127_1871276_1 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 440.0
HFD2_k127_1871276_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001941 225.0
HFD2_k127_1871276_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000000000000000001091 181.0
HFD2_k127_1871276_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000007124 179.0
HFD2_k127_1871276_5 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000008635 166.0
HFD2_k127_1886630_0 WD40-like Beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
HFD2_k127_1886630_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 391.0
HFD2_k127_1886630_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 296.0
HFD2_k127_1886630_3 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007435 272.0
HFD2_k127_1886630_4 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
HFD2_k127_1886630_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007476 258.0
HFD2_k127_1886630_6 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000001137 162.0
HFD2_k127_1886630_7 TIGRFAM TonB family K03832 - - 0.000000000000000006451 85.0
HFD2_k127_1900810_0 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
HFD2_k127_1900810_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 271.0
HFD2_k127_1900810_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000001276 211.0
HFD2_k127_1900810_3 virulence factor MVIN family protein K03980 - - 0.0000000000000000000000000000000000000000000001725 173.0
HFD2_k127_1900810_4 AAA domain - - - 0.00000000000000000000000000000000001079 138.0
HFD2_k127_1927178_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 6.898e-209 661.0
HFD2_k127_1927178_1 PFAM purine nucleoside permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
HFD2_k127_1927178_10 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00005131 46.0
HFD2_k127_1927178_11 Tetratricopeptide repeat - - - 0.000888 49.0
HFD2_k127_1927178_2 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 387.0
HFD2_k127_1927178_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 381.0
HFD2_k127_1927178_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 322.0
HFD2_k127_1927178_5 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 317.0
HFD2_k127_1927178_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 306.0
HFD2_k127_1927178_7 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000007615 262.0
HFD2_k127_1927178_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001021 253.0
HFD2_k127_1927178_9 mttA/Hcf106 family K03116 - - 0.0000000000000000000002372 104.0
HFD2_k127_1936336_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 550.0
HFD2_k127_1936336_1 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 513.0
HFD2_k127_1936336_2 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 448.0
HFD2_k127_1936336_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 376.0
HFD2_k127_1936336_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 304.0
HFD2_k127_1936336_5 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001689 256.0
HFD2_k127_1936336_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
HFD2_k127_1936336_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000004135 169.0
HFD2_k127_1936336_8 sterol desaturase - - - 0.000000000000000000000000002167 120.0
HFD2_k127_1936336_9 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000003978 113.0
HFD2_k127_19455_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 417.0
HFD2_k127_19455_1 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000004883 209.0
HFD2_k127_19455_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000004275 186.0
HFD2_k127_1949290_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 454.0
HFD2_k127_1949290_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
HFD2_k127_1949290_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 321.0
HFD2_k127_1949290_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 316.0
HFD2_k127_1949290_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000007755 186.0
HFD2_k127_1949290_5 selenocysteine lyase - - - 0.00000000000000000000000000001072 124.0
HFD2_k127_1952423_0 Caspase domain - - - 1.294e-240 756.0
HFD2_k127_1952423_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.159e-237 747.0
HFD2_k127_1952423_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002126 182.0
HFD2_k127_1952423_11 SnoaL-like domain - - - 0.0000000000000000000000000000000000000001149 156.0
HFD2_k127_1952423_12 ThiS family - - - 0.0000000000000005877 80.0
HFD2_k127_1952423_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.792e-212 672.0
HFD2_k127_1952423_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.228e-203 639.0
HFD2_k127_1952423_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 475.0
HFD2_k127_1952423_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 454.0
HFD2_k127_1952423_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 435.0
HFD2_k127_1952423_7 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001701 269.0
HFD2_k127_1952423_8 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000003137 236.0
HFD2_k127_1952423_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000008541 198.0
HFD2_k127_19869_0 PFAM peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 480.0
HFD2_k127_19869_1 Belongs to the Dps family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 313.0
HFD2_k127_19869_2 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000953 158.0
HFD2_k127_19869_3 Ferric uptake regulator family K09825 - - 0.000000000000000000000000000000001565 132.0
HFD2_k127_19869_4 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000001231 123.0
HFD2_k127_2001462_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 338.0
HFD2_k127_2001462_1 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
HFD2_k127_2001462_2 metal-dependent protease of the Pad1 Jab1 superfamily - - - 0.00000000000000000000000000003554 124.0
HFD2_k127_2020302_0 Protein of unknown function (DUF1595) - - - 5.706e-303 963.0
HFD2_k127_2020302_1 Protein of unknown function (DUF1552) - - - 9.227e-229 718.0
HFD2_k127_2020302_2 carboxylic ester hydrolase activity K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 592.0
HFD2_k127_2020302_3 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
HFD2_k127_2020302_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000001243 233.0
HFD2_k127_2020302_5 ribosylpyrimidine nucleosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002478 255.0
HFD2_k127_2023351_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000002014 139.0
HFD2_k127_2023351_1 - - - - 0.0000000000000000000000004149 113.0
HFD2_k127_2023351_2 O-antigen ligase like membrane protein - - - 0.00000000000002006 85.0
HFD2_k127_203456_0 Resolvase domain - - - 4.245e-295 920.0
HFD2_k127_203456_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000494 176.0
HFD2_k127_203456_2 Family of unknown function (DUF5372) - - - 0.00000000000000000000002284 102.0
HFD2_k127_203456_3 PFAM integrase - - - 0.0000000000000001753 83.0
HFD2_k127_203456_4 PFAM Integrase catalytic region - - - 0.00000000000001214 74.0
HFD2_k127_206331_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 415.0
HFD2_k127_206331_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003336 203.0
HFD2_k127_206331_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000004608 196.0
HFD2_k127_206331_3 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000261 191.0
HFD2_k127_206331_4 Protein of unknown function (DUF3738) K02172 - - 0.0000000000000000000000000000000000001914 154.0
HFD2_k127_206331_6 Hfq protein - - - 0.00000000000000000000000000000005275 127.0
HFD2_k127_206331_7 Tetratricopeptide repeat - - - 0.000000000000000000000000002367 113.0
HFD2_k127_206331_8 - - - - 0.0000000000000000000000002442 117.0
HFD2_k127_206331_9 - - - - 0.000000000000000005203 89.0
HFD2_k127_206922_0 Prolyl oligopeptidase family - - - 1.236e-299 931.0
HFD2_k127_206922_1 Ferrous iron transport protein B K04759 - - 1.013e-276 863.0
HFD2_k127_206922_2 DNA topological change K03168 - 5.99.1.2 1.046e-259 822.0
HFD2_k127_206922_3 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 412.0
HFD2_k127_206922_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
HFD2_k127_206922_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000001088 145.0
HFD2_k127_206922_7 - - - - 0.00000000000000000000000000000001343 134.0
HFD2_k127_206922_8 FeoA K04758 - - 0.0000000000000000000000009184 107.0
HFD2_k127_2074644_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 413.0
HFD2_k127_2074644_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 372.0
HFD2_k127_2074644_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
HFD2_k127_2074644_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
HFD2_k127_2074644_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000004815 201.0
HFD2_k127_2074644_5 Putative restriction endonuclease - - - 0.0000000000000000004133 95.0
HFD2_k127_2093945_0 Histidine kinase - - - 0.0 1054.0
HFD2_k127_2093945_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 478.0
HFD2_k127_2093945_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 301.0
HFD2_k127_2093945_3 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000001966 147.0
HFD2_k127_2093945_4 - - - - 0.000000000000000000000000003072 117.0
HFD2_k127_2093945_5 Membrane - - - 0.0000000000105 78.0
HFD2_k127_2103297_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 466.0
HFD2_k127_2103297_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 321.0
HFD2_k127_2103297_3 PFAM TadE family protein - - - 0.000000000002467 70.0
HFD2_k127_2108386_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 326.0
HFD2_k127_2108386_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 310.0
HFD2_k127_2129836_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.515e-313 967.0
HFD2_k127_2129836_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 589.0
HFD2_k127_2129836_2 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 323.0
HFD2_k127_2129836_3 TIGRFAM TonB K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001436 285.0
HFD2_k127_2129836_4 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000004789 226.0
HFD2_k127_2129836_5 Isoleucine patch superfamily enzyme, carbonic anhydrase acetyltransferase - - - 0.000000000000000000000000000000000000000000000006519 177.0
HFD2_k127_2129836_7 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000003655 108.0
HFD2_k127_2129836_9 - - - - 0.000000000000000002977 89.0
HFD2_k127_2133413_0 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000006368 217.0
HFD2_k127_2133413_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001614 221.0
HFD2_k127_2133413_2 - - - - 0.000000000000000000000000001496 123.0
HFD2_k127_2144002_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.274e-213 672.0
HFD2_k127_2144002_1 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 609.0
HFD2_k127_2144002_10 PFAM PIN domain - - - 0.0000000000000000005491 91.0
HFD2_k127_2144002_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001454 46.0
HFD2_k127_2144002_2 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 394.0
HFD2_k127_2144002_3 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 304.0
HFD2_k127_2144002_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004562 272.0
HFD2_k127_2144002_5 - - - - 0.000000000000000000000000000000000000000000000000000000002479 212.0
HFD2_k127_2144002_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000002735 203.0
HFD2_k127_2155507_0 Glycosyl transferases group 1 - - - 1.98e-305 957.0
HFD2_k127_2155507_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.221e-293 911.0
HFD2_k127_2155507_10 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 304.0
HFD2_k127_2155507_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 295.0
HFD2_k127_2155507_12 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 273.0
HFD2_k127_2155507_13 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001904 252.0
HFD2_k127_2155507_14 Bacterial regulatory proteins, luxR family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
HFD2_k127_2155507_15 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000007227 190.0
HFD2_k127_2155507_16 energy transducer activity - - - 0.0000000000000000000000000000000000000000000000001561 184.0
HFD2_k127_2155507_17 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000000000000001049 171.0
HFD2_k127_2155507_18 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000009965 145.0
HFD2_k127_2155507_19 Photosynthetic reaction centre cytochrome C subunit - - - 0.000000000000000000000000002314 116.0
HFD2_k127_2155507_2 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 597.0
HFD2_k127_2155507_20 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000006693 111.0
HFD2_k127_2155507_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000004358 84.0
HFD2_k127_2155507_23 - - - - 0.000000000000007428 86.0
HFD2_k127_2155507_24 PFAM CheW domain protein K03408 - - 0.000006089 53.0
HFD2_k127_2155507_26 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0004181 48.0
HFD2_k127_2155507_3 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 571.0
HFD2_k127_2155507_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 488.0
HFD2_k127_2155507_5 Ferrochelatase K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 385.0
HFD2_k127_2155507_6 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 379.0
HFD2_k127_2155507_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 368.0
HFD2_k127_2155507_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 346.0
HFD2_k127_2155507_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 309.0
HFD2_k127_2186990_0 long-chain fatty acid transporting porin activity - - - 4.351e-222 695.0
HFD2_k127_2186990_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 422.0
HFD2_k127_219359_0 xanthine dehydrogenase activity - - - 0.0 1190.0
HFD2_k127_219359_1 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 337.0
HFD2_k127_219359_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007525 273.0
HFD2_k127_219359_3 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001984 259.0
HFD2_k127_219359_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009036 256.0
HFD2_k127_219359_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 237.0
HFD2_k127_219359_6 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000018 168.0
HFD2_k127_219359_7 - - - - 0.000000000000000000000000000001538 124.0
HFD2_k127_219359_8 - - - - 0.0001326 51.0
HFD2_k127_2198659_0 Methyltransferase domain - - - 2.472e-213 672.0
HFD2_k127_2198659_1 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
HFD2_k127_2198659_2 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005705 258.0
HFD2_k127_2198659_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000007754 171.0
HFD2_k127_2198659_5 Colicin V production protein K03558 - - 0.00000000000000000000000000001346 126.0
HFD2_k127_2198659_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000004613 81.0
HFD2_k127_2200380_0 Spermine/spermidine synthase domain - - - 6.479e-265 841.0
HFD2_k127_2200380_1 TonB-dependent receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 415.0
HFD2_k127_2200380_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 324.0
HFD2_k127_2232620_0 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 406.0
HFD2_k127_2232620_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000124 277.0
HFD2_k127_2232620_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
HFD2_k127_2232620_3 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.0000001271 55.0
HFD2_k127_2232620_4 integral membrane protein - - - 0.0006279 48.0
HFD2_k127_2266110_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 480.0
HFD2_k127_2290439_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1106.0
HFD2_k127_2290439_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.343e-274 870.0
HFD2_k127_2290439_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 575.0
HFD2_k127_2290439_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 344.0
HFD2_k127_2290439_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000001342 187.0
HFD2_k127_2290439_5 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000003101 146.0
HFD2_k127_2290439_6 - - - - 0.000000000000000002571 94.0
HFD2_k127_2290439_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000005932 74.0
HFD2_k127_2290439_8 Cytochrome c K08738 - - 0.000000002796 64.0
HFD2_k127_2294073_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 598.0
HFD2_k127_2294073_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 316.0
HFD2_k127_2294073_2 - - - - 0.00000000000000000000000000006097 118.0
HFD2_k127_2314812_0 TonB-dependent receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 465.0
HFD2_k127_2314812_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006108 253.0
HFD2_k127_2314812_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000001185 219.0
HFD2_k127_2314812_3 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0003284 46.0
HFD2_k127_2320956_0 - - - - 0.0000000000000000000002481 109.0
HFD2_k127_2320956_1 - - - - 0.000000000003185 73.0
HFD2_k127_235504_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1197.0
HFD2_k127_235504_1 Major facilitator Superfamily K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 414.0
HFD2_k127_235504_2 Protein of unknown function (DUF3738) - - - 0.000000000000000000000000000000000002265 147.0
HFD2_k127_2362100_0 DEAD DEAH box K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 591.0
HFD2_k127_2362100_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 542.0
HFD2_k127_2362100_10 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000003925 183.0
HFD2_k127_2362100_12 - - - - 0.0000000000000000000000000000000000024 149.0
HFD2_k127_2362100_13 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.00000000000000000000000000000000001128 154.0
HFD2_k127_2362100_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 530.0
HFD2_k127_2362100_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 436.0
HFD2_k127_2362100_4 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 331.0
HFD2_k127_2362100_5 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 304.0
HFD2_k127_2362100_6 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001301 284.0
HFD2_k127_2362100_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005498 253.0
HFD2_k127_2362100_8 - - - - 0.000000000000000000000000000000000000000000000000000000175 206.0
HFD2_k127_2362100_9 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000002051 190.0
HFD2_k127_2371183_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.362e-207 656.0
HFD2_k127_2371183_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 539.0
HFD2_k127_2371183_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001204 244.0
HFD2_k127_2371183_4 RDD family - - - 0.0000000000000000000000000000000000000000000000002707 188.0
HFD2_k127_2371183_5 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000002921 163.0
HFD2_k127_2373997_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 8.693e-229 720.0
HFD2_k127_2373997_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 603.0
HFD2_k127_2373997_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000002511 56.0
HFD2_k127_2373997_2 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 508.0
HFD2_k127_2373997_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
HFD2_k127_2373997_4 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000004259 264.0
HFD2_k127_2373997_5 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
HFD2_k127_2373997_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000002497 203.0
HFD2_k127_2373997_7 mRNA binding K07339 - - 0.0000000000000000000000000001675 115.0
HFD2_k127_2373997_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000003834 114.0
HFD2_k127_2373997_9 Mycolic acid cyclopropane synthetase - - - 0.0000000000001476 73.0
HFD2_k127_2384423_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 530.0
HFD2_k127_2384423_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 529.0
HFD2_k127_2384423_10 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 332.0
HFD2_k127_2384423_11 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 336.0
HFD2_k127_2384423_12 Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 320.0
HFD2_k127_2384423_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000001873 221.0
HFD2_k127_2384423_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
HFD2_k127_2384423_15 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000481 160.0
HFD2_k127_2384423_16 - - - - 0.000000000000000000000000000000000001588 147.0
HFD2_k127_2384423_17 cheY-homologous receiver domain K03413 - - 0.000000000000000000000002342 106.0
HFD2_k127_2384423_18 - - - - 0.000000000000000000000007733 106.0
HFD2_k127_2384423_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 524.0
HFD2_k127_2384423_20 Acetyltransferase (GNAT) domain K00619 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 0.000000000002571 73.0
HFD2_k127_2384423_21 - - - - 0.0002799 46.0
HFD2_k127_2384423_3 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 472.0
HFD2_k127_2384423_4 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 421.0
HFD2_k127_2384423_5 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 404.0
HFD2_k127_2384423_6 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 396.0
HFD2_k127_2384423_7 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 396.0
HFD2_k127_2384423_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
HFD2_k127_2384423_9 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 360.0
HFD2_k127_241553_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.116e-227 733.0
HFD2_k127_241553_1 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 1.783e-201 666.0
HFD2_k127_241553_2 amino acid K03294 - - 6.768e-199 630.0
HFD2_k127_241553_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002767 246.0
HFD2_k127_241553_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002787 252.0
HFD2_k127_241553_5 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000557 233.0
HFD2_k127_241553_6 - - - - 0.000000000000000000000000000000000001032 149.0
HFD2_k127_241553_7 - - - - 0.00000000000000000000000000000006441 135.0
HFD2_k127_241553_8 - - - - 0.000000000000000000000007612 105.0
HFD2_k127_2454759_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 567.0
HFD2_k127_2454759_1 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 422.0
HFD2_k127_2454759_10 Cytochrome c K17760 - 1.1.9.1 0.0000000000000000134 86.0
HFD2_k127_2454759_11 PFAM YcfA-like protein - - - 0.000000000000001868 78.0
HFD2_k127_2454759_12 SnoaL-like domain - - - 0.0001304 51.0
HFD2_k127_2454759_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 420.0
HFD2_k127_2454759_3 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001332 274.0
HFD2_k127_2454759_4 gluconolactonase activity K01053 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001687 259.0
HFD2_k127_2454759_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005314 254.0
HFD2_k127_2454759_6 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000004496 211.0
HFD2_k127_2454759_7 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000005329 198.0
HFD2_k127_2454759_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000005285 175.0
HFD2_k127_2454759_9 - - - - 0.000000000000000000000000000000000000002742 158.0
HFD2_k127_246174_0 Elongation factor G, domain IV K02355 - - 0.0 1079.0
HFD2_k127_246174_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 471.0
HFD2_k127_246174_2 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 438.0
HFD2_k127_246174_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 417.0
HFD2_k127_246174_4 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 375.0
HFD2_k127_246174_5 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 347.0
HFD2_k127_246174_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002926 228.0
HFD2_k127_246174_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000001618 180.0
HFD2_k127_246174_8 Belongs to the frataxin family K06202,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.0000000000000000000000000000000000000002657 151.0
HFD2_k127_246174_9 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000001329 144.0
HFD2_k127_2542447_0 chaperone-mediated protein folding K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 625.0
HFD2_k127_2542447_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
HFD2_k127_2542447_2 Ankyrin repeat and KH K16726 GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147 - 0.00000000000000000000000000000411 137.0
HFD2_k127_2542447_3 - - - - 0.000000001032 64.0
HFD2_k127_254670_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 6.75e-259 805.0
HFD2_k127_254670_1 Prolyl-tRNA synthetase, C-terminal K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 479.0
HFD2_k127_2546886_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.298e-215 681.0
HFD2_k127_2546886_1 class II (D K K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 565.0
HFD2_k127_2546886_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 411.0
HFD2_k127_2546886_3 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 368.0
HFD2_k127_2552755_0 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000015 148.0
HFD2_k127_2552755_1 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000005564 109.0
HFD2_k127_2563494_0 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 307.0
HFD2_k127_2563494_1 Chromate transporter K07240 - - 0.00000000000000000000000000004969 123.0
HFD2_k127_2563494_2 Chromate transporter K07240 - - 0.00000000000000000000000000005377 129.0
HFD2_k127_2563494_3 PHP domain protein - - - 0.000000000000000000000001821 116.0
HFD2_k127_2563494_4 Carboxylesterase family - - - 0.000008604 57.0
HFD2_k127_2577513_0 Carboxypeptidase regulatory-like domain - - - 1.018e-227 744.0
HFD2_k127_2577513_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 4.054e-205 653.0
HFD2_k127_2577513_10 - - - - 0.00000001796 60.0
HFD2_k127_2577513_2 oxidoreductase activity - - - 1.07e-197 639.0
HFD2_k127_2577513_3 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 361.0
HFD2_k127_2577513_4 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 303.0
HFD2_k127_2577513_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 296.0
HFD2_k127_2577513_7 Low molecular weight phosphatase family - - - 0.000000000000000000000000000004927 125.0
HFD2_k127_2577513_8 mRNA binding K07339 - - 0.000000000000000000000006605 102.0
HFD2_k127_2577513_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001973 91.0
HFD2_k127_2598298_0 lipolytic protein G-D-S-L family - - - 1.121e-245 765.0
HFD2_k127_2598298_1 Belongs to the GcvT family K15064 - - 8.719e-195 617.0
HFD2_k127_2598298_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002111 256.0
HFD2_k127_2598298_11 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001494 223.0
HFD2_k127_2598298_12 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000001283 217.0
HFD2_k127_2598298_13 FCD K11475 - - 0.000000000000000000000000000000000000000000000000000006998 199.0
HFD2_k127_2598298_14 Ankyrin repeats (3 copies) - - - 0.000000000000000000000000000000000000001352 166.0
HFD2_k127_2598298_15 PQQ-like domain K17760 - 1.1.9.1 0.00000000000000000000000000000000000006613 152.0
HFD2_k127_2598298_16 Zn-dependent - - - 0.000000000000000000000000000000001314 142.0
HFD2_k127_2598298_17 - - - - 0.00000000000000000000000000000001774 138.0
HFD2_k127_2598298_18 - - - - 0.0000000000000000000000000000001059 135.0
HFD2_k127_2598298_19 - - - - 0.00000000000000000000000003584 117.0
HFD2_k127_2598298_2 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 615.0
HFD2_k127_2598298_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000002605 59.0
HFD2_k127_2598298_21 COG0477 Permeases of the major facilitator superfamily - - - 0.0004857 43.0
HFD2_k127_2598298_3 DNA topological change - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 561.0
HFD2_k127_2598298_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 501.0
HFD2_k127_2598298_5 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 488.0
HFD2_k127_2598298_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15242,K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 362.0
HFD2_k127_2598298_7 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 345.0
HFD2_k127_2598298_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 333.0
HFD2_k127_2598298_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 304.0
HFD2_k127_260316_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 322.0
HFD2_k127_260316_1 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000001095 126.0
HFD2_k127_260316_2 - - - - 0.000000000000000000948 88.0
HFD2_k127_2628033_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 472.0
HFD2_k127_2628033_1 Protein of unknown function (DUF721) - - - 0.00000000000000001225 87.0
HFD2_k127_2629094_0 Sodium:solute symporter family - - - 8.173e-272 846.0
HFD2_k127_2629094_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 572.0
HFD2_k127_2629094_10 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 332.0
HFD2_k127_2629094_11 ABC transporter K02049,K15578,K15579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 300.0
HFD2_k127_2629094_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000002071 246.0
HFD2_k127_2629094_13 type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000002951 243.0
HFD2_k127_2629094_14 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 246.0
HFD2_k127_2629094_15 ABC transporter K02049,K15578,K15579 - - 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
HFD2_k127_2629094_16 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000009377 224.0
HFD2_k127_2629094_17 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000586 199.0
HFD2_k127_2629094_18 - - - - 0.00000000000000000000000000000000000000000000000000004125 192.0
HFD2_k127_2629094_19 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000006545 122.0
HFD2_k127_2629094_2 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 468.0
HFD2_k127_2629094_20 Thioredoxin-like - - - 0.000000000000000000000000002073 116.0
HFD2_k127_2629094_21 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000002605 62.0
HFD2_k127_2629094_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 455.0
HFD2_k127_2629094_4 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 412.0
HFD2_k127_2629094_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
HFD2_k127_2629094_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 386.0
HFD2_k127_2629094_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 394.0
HFD2_k127_2629094_8 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 365.0
HFD2_k127_2629094_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 359.0
HFD2_k127_2631771_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 303.0
HFD2_k127_2631771_1 uroporphyrin-III C-methyltransferase activity K02302,K02303,K02304,K03795,K04719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000003095 240.0
HFD2_k127_2631771_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000002182 65.0
HFD2_k127_2649329_0 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 3.945e-212 666.0
HFD2_k127_2649329_1 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 635.0
HFD2_k127_2649329_2 Catechol dioxygenase N terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 401.0
HFD2_k127_2649329_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 366.0
HFD2_k127_2649329_4 - - - - 0.000000000000000000000000000000000000000000000000000000000003463 221.0
HFD2_k127_2649329_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000005318 169.0
HFD2_k127_2649329_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000001216 139.0
HFD2_k127_2649329_7 - - - - 0.0000000000000000000006266 101.0
HFD2_k127_2665556_0 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 345.0
HFD2_k127_2665556_1 Domain of unknown function (DUF4158) - - - 0.0000000000000000006171 88.0
HFD2_k127_2666351_0 surface antigen variable number - - - 1.236e-312 988.0
HFD2_k127_2666351_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 4.942e-239 786.0
HFD2_k127_2666351_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 454.0
HFD2_k127_2666351_3 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 415.0
HFD2_k127_2666351_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 327.0
HFD2_k127_2666351_5 MoeZ MoeB domain K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000001431 211.0
HFD2_k127_2666351_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000006474 121.0
HFD2_k127_2699678_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1174.0
HFD2_k127_2699678_1 Peptidase family M49 - - - 2.373e-222 700.0
HFD2_k127_2699678_10 Pfam:Gp37_Gp68 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
HFD2_k127_2699678_11 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002054 276.0
HFD2_k127_2699678_12 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002334 283.0
HFD2_k127_2699678_13 - - - - 0.00000000000000000000000000000000000000000000000000000000005172 215.0
HFD2_k127_2699678_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000009466 199.0
HFD2_k127_2699678_15 - - - - 0.000000000000000000000000000000000000000000000000001059 192.0
HFD2_k127_2699678_16 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000001556 185.0
HFD2_k127_2699678_17 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000002724 187.0
HFD2_k127_2699678_18 - - - - 0.000000000000000000000000000000000000000000001369 171.0
HFD2_k127_2699678_19 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000057 169.0
HFD2_k127_2699678_2 Protein tyrosine kinase - - - 1.081e-213 694.0
HFD2_k127_2699678_20 - - - - 0.000000000000000000000000000000000000000006107 165.0
HFD2_k127_2699678_21 DoxX K15977 - - 0.000000000000000000000000000000000001905 145.0
HFD2_k127_2699678_22 - - - - 0.000000000000000000000000006335 117.0
HFD2_k127_2699678_23 - - - - 0.00000000000000000000002949 111.0
HFD2_k127_2699678_24 - - - - 0.0000000000000001034 84.0
HFD2_k127_2699678_25 antisigma factor binding K04749 - - 0.00000000001876 72.0
HFD2_k127_2699678_27 - - - - 0.000007264 57.0
HFD2_k127_2699678_3 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.519e-212 670.0
HFD2_k127_2699678_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 572.0
HFD2_k127_2699678_5 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 477.0
HFD2_k127_2699678_6 gluconolactonase activity K07004,K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 472.0
HFD2_k127_2699678_7 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 466.0
HFD2_k127_2699678_8 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 443.0
HFD2_k127_2699678_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 398.0
HFD2_k127_2728435_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 353.0
HFD2_k127_2728435_1 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000004955 210.0
HFD2_k127_2728435_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000004404 198.0
HFD2_k127_2728435_3 S4 domain K14761 - - 0.00000000000000000000005478 103.0
HFD2_k127_2728435_4 PFAM Integrase, catalytic K07497 - - 0.0000001715 53.0
HFD2_k127_2728435_5 sh3 domain protein - - - 0.0007303 48.0
HFD2_k127_273091_0 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 336.0
HFD2_k127_2735746_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 574.0
HFD2_k127_2735746_1 response to copper ion K01187,K16915 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006222 282.0
HFD2_k127_2735746_2 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002052 265.0
HFD2_k127_2735746_3 - - - - 0.00000000000000000000000000000006124 140.0
HFD2_k127_2735746_4 Cold shock protein domain K03704 - - 0.0000000000000000000000000000007876 122.0
HFD2_k127_2735746_5 Cytochrome c - - - 0.000007211 52.0
HFD2_k127_2741202_0 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 7.368e-194 645.0
HFD2_k127_2741202_1 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 486.0
HFD2_k127_2741202_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 310.0
HFD2_k127_2741202_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HFD2_k127_2745625_0 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 563.0
HFD2_k127_2745625_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 416.0
HFD2_k127_2745625_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 372.0
HFD2_k127_2745625_3 cell redox homeostasis - - - 0.0000000000000000000000000000001249 131.0
HFD2_k127_2747039_0 Carboxypeptidase regulatory-like domain - - - 0.0 1405.0
HFD2_k127_2747039_1 DNA polymerase X K02347 - - 2.648e-271 844.0
HFD2_k127_2747039_10 excinuclease ABC activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 338.0
HFD2_k127_2747039_11 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 339.0
HFD2_k127_2747039_12 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 330.0
HFD2_k127_2747039_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 300.0
HFD2_k127_2747039_14 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 294.0
HFD2_k127_2747039_15 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000005038 222.0
HFD2_k127_2747039_16 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000002277 215.0
HFD2_k127_2747039_17 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000005532 125.0
HFD2_k127_2747039_19 Sulfotransferase family - - - 0.000000000000000002551 89.0
HFD2_k127_2747039_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 586.0
HFD2_k127_2747039_20 - - - - 0.0000000000000001889 81.0
HFD2_k127_2747039_22 - - - - 0.000000000000003727 79.0
HFD2_k127_2747039_23 - - - - 0.00000000000001982 79.0
HFD2_k127_2747039_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 520.0
HFD2_k127_2747039_4 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 456.0
HFD2_k127_2747039_5 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 388.0
HFD2_k127_2747039_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 375.0
HFD2_k127_2747039_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 354.0
HFD2_k127_2747039_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 355.0
HFD2_k127_2747039_9 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 351.0
HFD2_k127_2764389_0 PFAM Type II secretion system protein E K02652 - - 6.419e-291 899.0
HFD2_k127_2764389_1 L-lactate permease K03303 - - 1.329e-217 687.0
HFD2_k127_2764389_10 NIPSNAP - - - 0.00000000000000000000000000000000000000000002992 164.0
HFD2_k127_2764389_11 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000007555 171.0
HFD2_k127_2764389_12 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000001255 141.0
HFD2_k127_2764389_13 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000905 99.0
HFD2_k127_2764389_14 NIPSNAP - - - 0.000000000168 67.0
HFD2_k127_2764389_15 PFAM Fimbrial assembly family protein K02663 - - 0.000000007942 59.0
HFD2_k127_2764389_2 phosphorelay signal transduction system K07712,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 599.0
HFD2_k127_2764389_3 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 527.0
HFD2_k127_2764389_4 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 536.0
HFD2_k127_2764389_5 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 439.0
HFD2_k127_2764389_6 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
HFD2_k127_2764389_7 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000007796 237.0
HFD2_k127_2764389_8 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HFD2_k127_2764389_9 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000001032 207.0
HFD2_k127_2764986_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 9.187e-305 939.0
HFD2_k127_2764986_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 518.0
HFD2_k127_2764986_10 - - - - 0.0000000000000000002767 99.0
HFD2_k127_2764986_2 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 441.0
HFD2_k127_2764986_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 432.0
HFD2_k127_2764986_4 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
HFD2_k127_2764986_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 273.0
HFD2_k127_2764986_6 - - - - 0.00000000000000000000000000000000000000000000000000000002117 209.0
HFD2_k127_2764986_7 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000000000003214 188.0
HFD2_k127_2764986_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000001223 160.0
HFD2_k127_2764986_9 COG1082 Sugar phosphate isomerases epimerases K06606 - 5.3.99.11 0.000000000000000000007853 98.0
HFD2_k127_27890_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.991e-232 725.0
HFD2_k127_27890_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 576.0
HFD2_k127_27890_10 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000001807 156.0
HFD2_k127_27890_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000004069 74.0
HFD2_k127_27890_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000004643 70.0
HFD2_k127_27890_13 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000005293 74.0
HFD2_k127_27890_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 401.0
HFD2_k127_27890_3 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 399.0
HFD2_k127_27890_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 331.0
HFD2_k127_27890_5 uroporphyrin-III C-methyltransferase activity K02302,K02303,K02304,K03795,K04719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 293.0
HFD2_k127_27890_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001663 241.0
HFD2_k127_27890_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000005667 227.0
HFD2_k127_27890_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000002396 216.0
HFD2_k127_27890_9 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000002529 214.0
HFD2_k127_2793298_0 Carboxypeptidase regulatory-like domain - - - 3.93e-227 731.0
HFD2_k127_2793298_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 592.0
HFD2_k127_2793298_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 378.0
HFD2_k127_2793298_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 305.0
HFD2_k127_2793298_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007509 238.0
HFD2_k127_2793298_5 ArsC family - - - 0.0000000000000000000000000000000000000000000005393 173.0
HFD2_k127_2793298_6 - - - - 0.00000000000000000000000001755 117.0
HFD2_k127_2793298_8 - - - - 0.000004207 49.0
HFD2_k127_2797512_0 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 586.0
HFD2_k127_2797512_1 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 473.0
HFD2_k127_2797512_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
HFD2_k127_2797512_3 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000004476 235.0
HFD2_k127_2797512_4 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000001317 171.0
HFD2_k127_2797512_5 beta-lactamase activity K07126 - - 0.0000000000000000000001401 108.0
HFD2_k127_2797512_6 - - - - 0.0000000000004349 79.0
HFD2_k127_2797512_7 Fibronectin type 3 domain - - - 0.000297 54.0
HFD2_k127_2797512_8 COG3000 Sterol desaturase - - - 0.0004335 47.0
HFD2_k127_2803781_0 Putative glutamine amidotransferase - - - 3.512e-311 974.0
HFD2_k127_2803781_1 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 586.0
HFD2_k127_2803781_10 PFAM Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000305 241.0
HFD2_k127_2803781_11 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001607 227.0
HFD2_k127_2803781_12 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000001438 179.0
HFD2_k127_2803781_13 PFAM Inosine uridine-preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000004032 176.0
HFD2_k127_2803781_14 response to hydrogen peroxide K08985 - - 0.0000000000000000000000000006039 121.0
HFD2_k127_2803781_15 - - - - 0.00000000000000000000001446 110.0
HFD2_k127_2803781_16 arylsulfatase A - - - 0.00003064 52.0
HFD2_k127_2803781_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 562.0
HFD2_k127_2803781_3 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 429.0
HFD2_k127_2803781_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 396.0
HFD2_k127_2803781_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 362.0
HFD2_k127_2803781_6 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 346.0
HFD2_k127_2803781_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 337.0
HFD2_k127_2803781_8 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 292.0
HFD2_k127_2803781_9 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004294 247.0
HFD2_k127_2843044_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 6.519e-200 631.0
HFD2_k127_2843044_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 580.0
HFD2_k127_2843044_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
HFD2_k127_2843044_11 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000005838 229.0
HFD2_k127_2843044_12 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000001055 231.0
HFD2_k127_2843044_13 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002356 212.0
HFD2_k127_2843044_14 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000001953 200.0
HFD2_k127_2843044_15 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000119 167.0
HFD2_k127_2843044_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000006838 140.0
HFD2_k127_2843044_17 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000003412 131.0
HFD2_k127_2843044_18 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000004825 115.0
HFD2_k127_2843044_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 537.0
HFD2_k127_2843044_20 Helix-hairpin-helix motif - - - 0.000000000000000001352 92.0
HFD2_k127_2843044_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 506.0
HFD2_k127_2843044_4 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 424.0
HFD2_k127_2843044_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 400.0
HFD2_k127_2843044_6 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 353.0
HFD2_k127_2843044_7 tRNA pseudouridine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
HFD2_k127_2843044_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 314.0
HFD2_k127_2843044_9 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
HFD2_k127_2845877_0 DNA polymerase LigD, ligase domain K01971 - 6.5.1.1 1.593e-220 699.0
HFD2_k127_2845877_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 608.0
HFD2_k127_2845877_10 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
HFD2_k127_2845877_11 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
HFD2_k127_2845877_12 Belongs to the ompA family - - - 0.00000000000000000000000000000000003418 144.0
HFD2_k127_2845877_13 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000002314 121.0
HFD2_k127_2845877_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000001299 117.0
HFD2_k127_2845877_15 antisigma factor binding K04749 - - 0.000000000000000000002606 98.0
HFD2_k127_2845877_16 - - - - 0.00000000000000000002916 96.0
HFD2_k127_2845877_17 Bacterial PH domain K08981 - - 0.0000000000000000002721 96.0
HFD2_k127_2845877_18 - - - - 0.000000000000001822 79.0
HFD2_k127_2845877_19 - - - - 0.000000000000002389 79.0
HFD2_k127_2845877_2 PQQ-like domain K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 502.0
HFD2_k127_2845877_21 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000003693 64.0
HFD2_k127_2845877_22 Resolvase, N terminal domain - - - 0.00001321 49.0
HFD2_k127_2845877_23 PHP domain protein - - - 0.0009869 44.0
HFD2_k127_2845877_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 419.0
HFD2_k127_2845877_4 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 422.0
HFD2_k127_2845877_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 368.0
HFD2_k127_2845877_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 318.0
HFD2_k127_2845877_7 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
HFD2_k127_2845877_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000124 272.0
HFD2_k127_2845877_9 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002181 257.0
HFD2_k127_291406_0 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 586.0
HFD2_k127_291406_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 332.0
HFD2_k127_291406_2 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000001185 187.0
HFD2_k127_291406_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000002028 153.0
HFD2_k127_291406_4 Protein of unknown function (DUF3738) - - - 0.0000000000000000000000001463 117.0
HFD2_k127_291406_5 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000001181 99.0
HFD2_k127_291406_6 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 - 3.4.16.4 0.000001301 51.0
HFD2_k127_2916512_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.162e-204 646.0
HFD2_k127_2916512_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 540.0
HFD2_k127_2916512_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 314.0
HFD2_k127_2916512_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 295.0
HFD2_k127_2916512_12 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
HFD2_k127_2916512_13 Domain of unknown function (DUF4276) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006991 242.0
HFD2_k127_2916512_14 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000001383 237.0
HFD2_k127_2916512_15 - - - - 0.00000000000000000000000000000000000000000000000000000004552 217.0
HFD2_k127_2916512_16 lipopolysaccharide metabolic process K08309,K19804 - - 0.000000000000000000000000000000000000003323 160.0
HFD2_k127_2916512_17 PFAM response regulator receiver - - - 0.00000000000000000000000000000000002024 140.0
HFD2_k127_2916512_18 - - - - 0.000000000000000000000000000007239 124.0
HFD2_k127_2916512_19 - - - - 0.0000000000000000000001105 99.0
HFD2_k127_2916512_2 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 483.0
HFD2_k127_2916512_20 PFAM Alpha beta hydrolase of - - - 0.0000000000000002123 91.0
HFD2_k127_2916512_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000003608 58.0
HFD2_k127_2916512_3 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 468.0
HFD2_k127_2916512_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 458.0
HFD2_k127_2916512_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 449.0
HFD2_k127_2916512_6 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 429.0
HFD2_k127_2916512_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 387.0
HFD2_k127_2916512_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 379.0
HFD2_k127_2916512_9 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 353.0
HFD2_k127_2917258_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 2.15e-238 742.0
HFD2_k127_2917258_1 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 409.0
HFD2_k127_2917258_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003473 273.0
HFD2_k127_2917258_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 258.0
HFD2_k127_2917258_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005946 253.0
HFD2_k127_2917258_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000008374 227.0
HFD2_k127_2937039_0 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
HFD2_k127_2937039_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000001304 177.0
HFD2_k127_2937039_2 - - - - 0.0000000000000000000000000000000000000000156 159.0
HFD2_k127_2937039_3 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000002375 121.0
HFD2_k127_2937039_4 - - - - 0.0000000000000000001051 94.0
HFD2_k127_2937039_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000457 55.0
HFD2_k127_2970135_0 ABC transporter K11085 - - 3.006e-238 756.0
HFD2_k127_2970135_1 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002094 249.0
HFD2_k127_2970135_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000002139 128.0
HFD2_k127_2976898_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1248.0
HFD2_k127_2976898_1 Amino acid permease - - - 4.904e-319 992.0
HFD2_k127_2976898_10 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 323.0
HFD2_k127_2976898_11 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 289.0
HFD2_k127_2976898_12 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 282.0
HFD2_k127_2976898_13 FecCD transport family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
HFD2_k127_2976898_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000494 272.0
HFD2_k127_2976898_15 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003903 263.0
HFD2_k127_2976898_16 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003346 255.0
HFD2_k127_2976898_17 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001531 268.0
HFD2_k127_2976898_18 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001003 232.0
HFD2_k127_2976898_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000002121 226.0
HFD2_k127_2976898_2 PFAM Cytochrome c assembly protein K02198 - - 5.963e-295 919.0
HFD2_k127_2976898_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
HFD2_k127_2976898_21 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000004587 194.0
HFD2_k127_2976898_22 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000002675 190.0
HFD2_k127_2976898_23 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000001846 170.0
HFD2_k127_2976898_24 - - - - 0.0000000000000000000000000000000000000001154 153.0
HFD2_k127_2976898_25 cobinamide kinase activity K02231,K02232 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62,6.3.5.10 0.0000000000000000000000000000000000000005579 156.0
HFD2_k127_2976898_26 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000002024 140.0
HFD2_k127_2976898_27 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000008481 138.0
HFD2_k127_2976898_28 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000003655 139.0
HFD2_k127_2976898_29 - - - - 0.00000000000000000000000002955 112.0
HFD2_k127_2976898_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 462.0
HFD2_k127_2976898_30 - - - - 0.00000000000000000000003327 110.0
HFD2_k127_2976898_31 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000002501 106.0
HFD2_k127_2976898_32 peptidyl-tyrosine sulfation - - - 0.0000000000000000006609 96.0
HFD2_k127_2976898_33 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000001655 91.0
HFD2_k127_2976898_34 - - - - 0.0000000000000001333 83.0
HFD2_k127_2976898_35 Mut7-C RNAse domain - - - 0.00000000000003256 77.0
HFD2_k127_2976898_36 Protein of unknown function (DUF433) - - - 0.000000000009157 67.0
HFD2_k127_2976898_37 monooxygenase activity - - - 0.000000001998 61.0
HFD2_k127_2976898_38 - - - - 0.00000162 55.0
HFD2_k127_2976898_39 Cytochrome c7 and related cytochrome c - - - 0.0001698 50.0
HFD2_k127_2976898_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 460.0
HFD2_k127_2976898_5 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 409.0
HFD2_k127_2976898_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 357.0
HFD2_k127_2976898_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
HFD2_k127_2976898_8 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 338.0
HFD2_k127_2976898_9 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 317.0
HFD2_k127_300453_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 304.0
HFD2_k127_3011204_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 2.045e-291 911.0
HFD2_k127_3011204_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.713e-237 743.0
HFD2_k127_3011204_10 Ureide permease K05340 - - 0.000000000000000000000000000000000000000000000000000000000003119 221.0
HFD2_k127_3011204_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002624 184.0
HFD2_k127_3011204_13 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000008996 187.0
HFD2_k127_3011204_14 STAS domain K04749 - - 0.00000000000000000000000000000000000000002725 155.0
HFD2_k127_3011204_15 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000001221 146.0
HFD2_k127_3011204_16 Smr domain - - - 0.000000000000000000000000000000000001878 140.0
HFD2_k127_3011204_17 Biotin-requiring enzyme - - - 0.00000000000000000000000002015 115.0
HFD2_k127_3011204_18 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000001204 69.0
HFD2_k127_3011204_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 8.113e-207 650.0
HFD2_k127_3011204_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 604.0
HFD2_k127_3011204_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 452.0
HFD2_k127_3011204_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 425.0
HFD2_k127_3011204_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 410.0
HFD2_k127_3011204_7 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
HFD2_k127_3011204_8 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 302.0
HFD2_k127_3011204_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001377 275.0
HFD2_k127_3018724_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 489.0
HFD2_k127_3018724_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 305.0
HFD2_k127_3027805_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 536.0
HFD2_k127_3027805_1 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 445.0
HFD2_k127_3027805_2 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 445.0
HFD2_k127_3045809_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 518.0
HFD2_k127_3045809_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 451.0
HFD2_k127_3045809_2 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000002404 171.0
HFD2_k127_3045809_3 - - - - 0.00000000000000113 90.0
HFD2_k127_3045809_4 - - - - 0.000000000000002892 79.0
HFD2_k127_3045809_5 - - - - 0.0000000001746 66.0
HFD2_k127_3049849_0 cellulose binding - - - 3.887e-224 696.0
HFD2_k127_3049849_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.227e-202 635.0
HFD2_k127_3049849_10 - - - - 0.000000000000000000000000000000000001053 152.0
HFD2_k127_3049849_11 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.00000000000000000000000000002035 125.0
HFD2_k127_3049849_12 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000001415 119.0
HFD2_k127_3049849_2 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 435.0
HFD2_k127_3049849_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 374.0
HFD2_k127_3049849_4 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000008098 204.0
HFD2_k127_3049849_5 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000001148 212.0
HFD2_k127_3049849_6 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000194 211.0
HFD2_k127_3049849_7 - - - - 0.00000000000000000000000000000000000000000000000000003371 198.0
HFD2_k127_3049849_8 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000000000004367 169.0
HFD2_k127_3049849_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000001398 168.0
HFD2_k127_3060436_0 - - - - 1.157e-246 779.0
HFD2_k127_3060436_1 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 582.0
HFD2_k127_3060436_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 547.0
HFD2_k127_3060436_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 302.0
HFD2_k127_3060436_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 306.0
HFD2_k127_3060436_5 HDOD domain K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000002736 173.0
HFD2_k127_3060436_6 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000002477 115.0
HFD2_k127_3104832_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 554.0
HFD2_k127_3104832_1 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 563.0
HFD2_k127_3104832_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 385.0
HFD2_k127_3104832_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 328.0
HFD2_k127_3104832_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000331 212.0
HFD2_k127_3146738_0 TonB-dependent receptor - - - 5.967e-272 877.0
HFD2_k127_3146738_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 574.0
HFD2_k127_3146738_2 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 321.0
HFD2_k127_3174589_0 Cytochrome c, class I - - - 1.374e-259 822.0
HFD2_k127_3174589_1 Protein of unknown function (DUF1501) - - - 9.632e-194 620.0
HFD2_k127_3174589_11 - - - - 0.000000000000000000000000008162 114.0
HFD2_k127_3174589_14 Dehydrogenase K00117 - 1.1.5.2 0.0000000003086 67.0
HFD2_k127_3174589_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 548.0
HFD2_k127_3174589_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 437.0
HFD2_k127_3174589_4 Thymidylate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 414.0
HFD2_k127_3174589_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002394 299.0
HFD2_k127_3174589_6 - - - - 0.000000000000000000000000000000000000000000000000000000000005013 221.0
HFD2_k127_3174589_8 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000071 147.0
HFD2_k127_3174589_9 HAD-hyrolase-like - - - 0.000000000000000000000000000000000001747 146.0
HFD2_k127_3202667_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 475.0
HFD2_k127_3202667_1 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 363.0
HFD2_k127_3202667_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 300.0
HFD2_k127_3202667_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 278.0
HFD2_k127_3202667_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000005966 220.0
HFD2_k127_3202667_5 TIGRFAM molybdenum cofactor synthesis - - - 0.00000000000000000000000000000000000000000000000009552 182.0
HFD2_k127_3202667_6 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000006835 165.0
HFD2_k127_3202667_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000683 129.0
HFD2_k127_3202667_8 - - - - 0.0000000000000000001871 89.0
HFD2_k127_3202667_9 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000001029 73.0
HFD2_k127_3207959_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1028.0
HFD2_k127_3207959_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 458.0
HFD2_k127_3207959_2 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001719 235.0
HFD2_k127_3207959_3 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000001858 163.0
HFD2_k127_3207959_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000009216 153.0
HFD2_k127_3207959_5 Ribosomal_S15 K02956 - - 0.0000000000000000000000000000001348 125.0
HFD2_k127_3207959_6 SnoaL-like domain - - - 0.00000000000000000000001172 108.0
HFD2_k127_3215009_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 9.937e-216 699.0
HFD2_k127_3215009_1 DNA topological change K03168 - 5.99.1.2 3.037e-200 650.0
HFD2_k127_3215009_10 - - - - 0.0000000000000000009076 93.0
HFD2_k127_3215009_11 heat shock protein binding K03686 - - 0.00000000000007426 77.0
HFD2_k127_3215009_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000001709 68.0
HFD2_k127_3215009_13 - - - - 0.0003683 45.0
HFD2_k127_3215009_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 507.0
HFD2_k127_3215009_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 400.0
HFD2_k127_3215009_4 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 377.0
HFD2_k127_3215009_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 359.0
HFD2_k127_3215009_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 364.0
HFD2_k127_3215009_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 325.0
HFD2_k127_3215009_8 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000238 230.0
HFD2_k127_3215009_9 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 249.0
HFD2_k127_3265714_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 1.622e-265 825.0
HFD2_k127_3265714_1 Permease, YjgP YjgQ - - - 5.719e-230 735.0
HFD2_k127_3265714_10 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000319 276.0
HFD2_k127_3265714_11 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001102 255.0
HFD2_k127_3265714_12 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003433 275.0
HFD2_k127_3265714_13 response regulator K02479,K07684,K07685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008015 252.0
HFD2_k127_3265714_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
HFD2_k127_3265714_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001477 229.0
HFD2_k127_3265714_16 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000001747 241.0
HFD2_k127_3265714_17 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000000000000000000001479 201.0
HFD2_k127_3265714_18 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000001123 197.0
HFD2_k127_3265714_19 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000001207 179.0
HFD2_k127_3265714_2 PFAM peptidase U62 modulator of DNA gyrase - - - 4.313e-200 641.0
HFD2_k127_3265714_20 - - - - 0.00000000000000000000000000000000000000000001086 172.0
HFD2_k127_3265714_21 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000006254 165.0
HFD2_k127_3265714_22 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000001483 143.0
HFD2_k127_3265714_24 iron ion homeostasis - - - 0.000000000000000000003473 103.0
HFD2_k127_3265714_25 Redoxin - - - 0.000000000000000003905 91.0
HFD2_k127_3265714_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890,K06878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
HFD2_k127_3265714_4 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 518.0
HFD2_k127_3265714_5 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 499.0
HFD2_k127_3265714_6 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 380.0
HFD2_k127_3265714_7 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 341.0
HFD2_k127_3265714_8 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 341.0
HFD2_k127_3265714_9 PFAM amino acid permease-associated region K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 308.0
HFD2_k127_3274698_0 PQQ-like domain K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 522.0
HFD2_k127_3274698_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 349.0
HFD2_k127_3274698_2 - - - - 0.0000000000000000000000003561 116.0
HFD2_k127_3274698_3 Resolvase, N terminal domain - - - 0.000000000000000001358 90.0
HFD2_k127_3293667_0 TOBE domain K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 308.0
HFD2_k127_3293667_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 291.0
HFD2_k127_3299802_0 efflux transmembrane transporter activity - - - 6.467e-317 989.0
HFD2_k127_3299802_1 Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 5.331e-200 629.0
HFD2_k127_3299802_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000003568 140.0
HFD2_k127_3334747_0 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 396.0
HFD2_k127_3334747_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 356.0
HFD2_k127_3334747_2 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 336.0
HFD2_k127_3334747_3 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001195 274.0
HFD2_k127_3334747_4 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
HFD2_k127_3334747_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000002599 230.0
HFD2_k127_3334747_6 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000005935 152.0
HFD2_k127_3334747_7 SpoVT / AbrB like domain K07172 - - 0.00000000000000003362 84.0
HFD2_k127_3338126_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 2.973e-206 663.0
HFD2_k127_3338126_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 421.0
HFD2_k127_3338126_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000004293 199.0
HFD2_k127_3338126_3 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000006119 148.0
HFD2_k127_3338126_4 - - - - 0.000000000000000000000000000003663 128.0
HFD2_k127_3338126_5 - - - - 0.000000000000000000000000006745 123.0
HFD2_k127_3338126_6 Carbon-nitrogen hydrolase - - - 0.00000000008473 64.0
HFD2_k127_339026_0 - - - - 0.0000000000000000000000000000000000000000000000000000004295 203.0
HFD2_k127_339026_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000006685 179.0
HFD2_k127_339026_2 phosphorelay signal transduction system - - - 0.000000000002895 71.0
HFD2_k127_339026_3 Anti-sigma-K factor rskA - - - 0.00000000007122 72.0
HFD2_k127_3436061_0 DNA topological change - - - 7.183e-207 671.0
HFD2_k127_3436061_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 384.0
HFD2_k127_3436061_10 - - - - 0.00000000000000000000000000004173 133.0
HFD2_k127_3436061_11 Bacterial-like globin K06886 - - 0.0000000000000000000000000002091 124.0
HFD2_k127_3436061_12 - - - - 0.000000000000000000000000001247 117.0
HFD2_k127_3436061_13 - - - - 0.000000000000000000000000002019 124.0
HFD2_k127_3436061_14 - - - - 0.000000000000000000000002561 118.0
HFD2_k127_3436061_2 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000177 239.0
HFD2_k127_3436061_3 DinB family - - - 0.000000000000000000000000000000000002059 145.0
HFD2_k127_3436061_4 - - - - 0.000000000000000000000000000000002429 136.0
HFD2_k127_3436061_5 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000001678 130.0
HFD2_k127_3436061_6 Transcriptional regulator IclR K13641 - - 0.0000000000000000000000000000003773 141.0
HFD2_k127_3436061_7 - - - - 0.0000000000000000000000000000006667 132.0
HFD2_k127_3436061_8 - - - - 0.00000000000000000000000000000764 121.0
HFD2_k127_3436061_9 - - - - 0.00000000000000000000000000002989 121.0
HFD2_k127_34454_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 5.324e-254 802.0
HFD2_k127_34454_1 COG0457 FOG TPR repeat - - - 0.00000000000008643 81.0
HFD2_k127_3454129_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 417.0
HFD2_k127_3454129_1 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 362.0
HFD2_k127_3454129_2 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007337 281.0
HFD2_k127_3454129_3 Glycoside hydrolase family 44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000343 260.0
HFD2_k127_3454129_4 metallopeptidase activity K01179,K20276 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000144 235.0
HFD2_k127_3454129_5 cellulase activity - - - 0.00000000000000000652 98.0
HFD2_k127_3454129_6 In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 K09020 - 3.5.1.110 0.000000000001762 70.0
HFD2_k127_3463009_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.947e-201 639.0
HFD2_k127_3463009_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 527.0
HFD2_k127_3463009_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 506.0
HFD2_k127_3463009_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 503.0
HFD2_k127_3463009_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000009441 211.0
HFD2_k127_3463009_5 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000002897 49.0
HFD2_k127_3465242_0 symporter activity - - - 2.142e-204 646.0
HFD2_k127_3465242_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 548.0
HFD2_k127_3465242_2 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 341.0
HFD2_k127_3465242_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 288.0
HFD2_k127_3506625_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 627.0
HFD2_k127_3506625_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 333.0
HFD2_k127_3506625_2 DinB family - - - 0.00000000000000000000000000000002472 133.0
HFD2_k127_3508121_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 554.0
HFD2_k127_3508121_1 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 447.0
HFD2_k127_3513462_0 chlorophyll binding - - - 0.0 2209.0
HFD2_k127_3513462_1 - - - - 6.938e-317 1011.0
HFD2_k127_3513462_2 - - - - 1.233e-254 823.0
HFD2_k127_3513462_3 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 583.0
HFD2_k127_3513462_4 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 413.0
HFD2_k127_3513462_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
HFD2_k127_3513462_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001601 279.0
HFD2_k127_3513462_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000002732 223.0
HFD2_k127_3513462_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000002216 151.0
HFD2_k127_3513462_9 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000001689 93.0
HFD2_k127_3528771_0 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 482.0
HFD2_k127_3528771_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 407.0
HFD2_k127_3528771_2 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
HFD2_k127_3528771_3 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000001364 212.0
HFD2_k127_3528771_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001151 198.0
HFD2_k127_3528771_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000004677 180.0
HFD2_k127_3528771_6 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000001647 104.0
HFD2_k127_3538221_0 AcrB/AcrD/AcrF family - - - 0.0 1364.0
HFD2_k127_3538221_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 1.574e-204 667.0
HFD2_k127_3538221_11 Haem-degrading - - - 0.00000000000004525 77.0
HFD2_k127_3538221_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 446.0
HFD2_k127_3538221_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 416.0
HFD2_k127_3538221_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 345.0
HFD2_k127_3538221_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 337.0
HFD2_k127_3538221_6 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000001826 202.0
HFD2_k127_3538221_7 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000003534 139.0
HFD2_k127_3538221_9 YtxH-like protein - - - 0.0000000000000000000001896 98.0
HFD2_k127_3560978_0 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 465.0
HFD2_k127_3560978_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 432.0
HFD2_k127_3560978_2 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 387.0
HFD2_k127_3560978_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 262.0
HFD2_k127_3560978_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002459 261.0
HFD2_k127_3560978_5 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000003324 214.0
HFD2_k127_3560978_6 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000005951 114.0
HFD2_k127_3590522_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 613.0
HFD2_k127_3590522_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000005438 214.0
HFD2_k127_3590522_2 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000000204 149.0
HFD2_k127_3590522_3 RNA recognition motif - - - 0.00000000000000000000000000000004016 129.0
HFD2_k127_3599654_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.107e-253 795.0
HFD2_k127_3599654_1 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000003585 202.0
HFD2_k127_3599654_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000159 178.0
HFD2_k127_3599654_3 - - - - 0.000000000000000000002811 108.0
HFD2_k127_3614072_0 TonB dependent receptor K16090 - - 8.323e-224 710.0
HFD2_k127_3614072_1 protein import - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 381.0
HFD2_k127_3614072_10 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000008198 114.0
HFD2_k127_3614072_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000004075 102.0
HFD2_k127_3614072_12 Cell division protein ZapA K09888 - - 0.00000000000000000002862 97.0
HFD2_k127_3614072_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 314.0
HFD2_k127_3614072_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000007707 202.0
HFD2_k127_3614072_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000002464 192.0
HFD2_k127_3614072_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000000003656 184.0
HFD2_k127_3614072_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000804 173.0
HFD2_k127_3614072_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000001914 176.0
HFD2_k127_3614072_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000004461 141.0
HFD2_k127_3622142_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
HFD2_k127_3622142_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 382.0
HFD2_k127_3622142_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007279 265.0
HFD2_k127_3622142_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
HFD2_k127_3622142_4 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000000005204 164.0
HFD2_k127_3622142_5 - - - - 0.000000000000000000000000000000000000004165 152.0
HFD2_k127_3622142_6 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000005079 119.0
HFD2_k127_3622142_7 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000269 102.0
HFD2_k127_3622142_8 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000223 76.0
HFD2_k127_3640609_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.161e-272 850.0
HFD2_k127_3640609_1 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 605.0
HFD2_k127_3640609_10 PFAM OmpA K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HFD2_k127_3640609_11 flagellar basal-body rod protein FlgC K02388 - - 0.0000000000000000000000000000000000000000000000000000000000008474 212.0
HFD2_k127_3640609_12 Flagellar hook-associated protein 2 N-terminus - - - 0.00000000000000000000000000000000000000000000000001246 198.0
HFD2_k127_3640609_13 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000003778 164.0
HFD2_k127_3640609_14 flagellar motor switch protein FliM K02416 - - 0.0000000000000000000000000000000000000006364 159.0
HFD2_k127_3640609_15 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000001418 139.0
HFD2_k127_3640609_16 diguanylate cyclase activity - - - 0.0000000000000000000000000000001484 141.0
HFD2_k127_3640609_17 Universal stress protein family - - - 0.00000000000000000000000000003373 128.0
HFD2_k127_3640609_18 PFAM flagellar FlbD family protein K02385 - - 0.00000000000000000002854 94.0
HFD2_k127_3640609_19 Cytochrome c - - - 0.000000000000000005723 91.0
HFD2_k127_3640609_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 495.0
HFD2_k127_3640609_20 Flagellar assembly protein FliH K02411 - - 0.00000000000000008031 88.0
HFD2_k127_3640609_21 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000009905 84.0
HFD2_k127_3640609_23 universal stress protein - - - 0.000000003511 67.0
HFD2_k127_3640609_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 379.0
HFD2_k127_3640609_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 387.0
HFD2_k127_3640609_5 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 366.0
HFD2_k127_3640609_6 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 342.0
HFD2_k127_3640609_7 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 333.0
HFD2_k127_3640609_8 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 306.0
HFD2_k127_3640609_9 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
HFD2_k127_3662152_0 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 554.0
HFD2_k127_3662152_1 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 503.0
HFD2_k127_3662152_3 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000001226 54.0
HFD2_k127_3683060_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000383 269.0
HFD2_k127_3683060_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000009043 227.0
HFD2_k127_3683060_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000003951 192.0
HFD2_k127_3692551_0 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 303.0
HFD2_k127_3692551_1 Bacterial export proteins, family 1 K02421 - - 0.00000000000000000000000000000000000000000000000000000000003154 218.0
HFD2_k127_3692551_2 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000000008322 121.0
HFD2_k127_3692551_3 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.00000000000004175 73.0
HFD2_k127_3692551_4 flagellar K02418 - - 0.0000000001505 65.0
HFD2_k127_3719539_0 Carboxypeptidase regulatory-like domain - - - 6.051e-194 638.0
HFD2_k127_3719539_1 Glycosyl transferase, family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 300.0
HFD2_k127_3719539_2 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000004562 161.0
HFD2_k127_3719539_3 EamA-like transporter family - - - 0.0000000000000000000000000002309 122.0
HFD2_k127_3719539_4 EamA-like transporter family - - - 0.00000000000000000000000002923 109.0
HFD2_k127_3734005_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 567.0
HFD2_k127_3734005_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 533.0
HFD2_k127_3734005_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 346.0
HFD2_k127_3742123_0 SMART Elongator protein 3 MiaB NifB - - - 4.011e-228 713.0
HFD2_k127_3742123_1 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 571.0
HFD2_k127_3748636_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 326.0
HFD2_k127_3748636_1 - - - - 0.00000000000000002947 84.0
HFD2_k127_375987_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 401.0
HFD2_k127_375987_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
HFD2_k127_375987_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
HFD2_k127_3765305_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000002998 179.0
HFD2_k127_3765305_1 Redoxin - - - 0.0000000000000000000000000008978 119.0
HFD2_k127_3765305_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000001821 108.0
HFD2_k127_3765305_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000001463 94.0
HFD2_k127_3765305_4 Aminotransferase class I and II K00375 - - 0.000000000000002031 81.0
HFD2_k127_3765305_5 Membrane - - - 0.000000000001044 79.0
HFD2_k127_3765305_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.0000000000061 68.0
HFD2_k127_3790844_0 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 438.0
HFD2_k127_3790844_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 390.0
HFD2_k127_3790844_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 396.0
HFD2_k127_3790844_3 - - - - 0.00000000000000000000000000000000000000000000000000006634 190.0
HFD2_k127_3790844_4 - - - - 0.00000000000000000000000000000000000000000001794 173.0
HFD2_k127_3790844_5 - - - - 0.00000000000000000000000375 102.0
HFD2_k127_3790844_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000001036 51.0
HFD2_k127_3825037_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 385.0
HFD2_k127_3825037_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000009302 233.0
HFD2_k127_3825037_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000006677 199.0
HFD2_k127_3825037_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000109 216.0
HFD2_k127_3825037_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
HFD2_k127_3825037_5 Carbon-nitrogen hydrolase - - - 0.00000000000000001065 90.0
HFD2_k127_3837221_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 520.0
HFD2_k127_3837221_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 457.0
HFD2_k127_3837221_2 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 422.0
HFD2_k127_3837221_3 class II (D K K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000001239 231.0
HFD2_k127_3837221_4 FtsZ-dependent cytokinesis K03975 - - 0.000000000000000000000000000000000000000000000000000003387 194.0
HFD2_k127_3837221_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000009406 106.0
HFD2_k127_3837221_6 mRNA binding - - - 0.0000000000000000005435 88.0
HFD2_k127_3880265_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.305e-321 1009.0
HFD2_k127_3880265_1 Participates in both transcription termination and antitermination K02600 - - 4.279e-201 636.0
HFD2_k127_3880265_3 - K02172 - - 0.000000000000000000000000000000000000000000000000000000000004333 218.0
HFD2_k127_3880265_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000002424 208.0
HFD2_k127_3880265_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000915 182.0
HFD2_k127_3880265_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000006119 138.0
HFD2_k127_3880265_7 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000698 124.0
HFD2_k127_3880265_8 - - - - 0.00000000000002319 81.0
HFD2_k127_3882277_0 - - - - 7.58e-262 819.0
HFD2_k127_3882277_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.832e-232 740.0
HFD2_k127_3882277_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000007166 107.0
HFD2_k127_3882277_11 Putative restriction endonuclease - - - 0.000000000000000000001549 101.0
HFD2_k127_3882277_12 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000001012 79.0
HFD2_k127_3882277_2 Required for chromosome condensation and partitioning K03529 - - 4.859e-228 728.0
HFD2_k127_3882277_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 3.356e-208 676.0
HFD2_k127_3882277_4 protein-disulfide reductase activity K04084 - 1.8.1.8 1.091e-207 662.0
HFD2_k127_3882277_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 468.0
HFD2_k127_3882277_6 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 445.0
HFD2_k127_3882277_7 nitrite transmembrane transporter activity K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 334.0
HFD2_k127_3882277_8 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000297 193.0
HFD2_k127_3882277_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000003712 134.0
HFD2_k127_3889723_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 318.0
HFD2_k127_3889723_1 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000001108 177.0
HFD2_k127_3889723_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000002229 114.0
HFD2_k127_3889723_3 - - - - 0.00000000000000002399 87.0
HFD2_k127_3941681_0 FAD linked oxidase domain protein - - - 6.654e-270 874.0
HFD2_k127_3941681_1 G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 399.0
HFD2_k127_3941681_10 - - - - 0.0000000000967 65.0
HFD2_k127_3941681_11 - - - - 0.000000006694 62.0
HFD2_k127_3941681_2 Major Facilitator Superfamily K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 385.0
HFD2_k127_3941681_3 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 319.0
HFD2_k127_3941681_4 teichoic acid transport K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003979 280.0
HFD2_k127_3941681_5 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003589 276.0
HFD2_k127_3941681_6 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009059 261.0
HFD2_k127_3941681_7 - - - - 0.0000000000000000000000000000003342 134.0
HFD2_k127_3941681_8 - - - - 0.000000000000000000000001083 109.0
HFD2_k127_3941681_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001598 69.0
HFD2_k127_3947588_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1092.0
HFD2_k127_3947588_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 358.0
HFD2_k127_3947588_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HFD2_k127_3947588_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000284 256.0
HFD2_k127_3963772_0 PFAM Ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 584.0
HFD2_k127_3963772_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 578.0
HFD2_k127_3963772_10 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000007405 114.0
HFD2_k127_3963772_11 - - - - 0.000000000000000000001662 106.0
HFD2_k127_3963772_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 517.0
HFD2_k127_3963772_3 xylulokinase activity K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 478.0
HFD2_k127_3963772_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 341.0
HFD2_k127_3963772_5 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 306.0
HFD2_k127_3963772_6 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000007947 241.0
HFD2_k127_3963772_7 - - - - 0.0000000000000000000000000000000000000000000000000000000003227 211.0
HFD2_k127_3963772_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000004104 163.0
HFD2_k127_3980664_0 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 541.0
HFD2_k127_3980664_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 530.0
HFD2_k127_3980664_2 maleylacetate reductase K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 357.0
HFD2_k127_3980664_3 - - - - 0.00000000000000000000000000000001423 143.0
HFD2_k127_3980664_4 Methyltransferase domain - - - 0.0000000000000000000001849 107.0
HFD2_k127_3987686_0 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.0000000000000000000000000000000000000000000000000000002789 196.0
HFD2_k127_3987686_1 - - - - 0.00000000000000000000000000000003875 135.0
HFD2_k127_3987686_2 - - - - 0.000000000000000000000000001211 123.0
HFD2_k127_3987686_3 - - - - 0.0000000000000000000013 101.0
HFD2_k127_3987686_4 Haem-degrading - - - 0.00000000000000007786 89.0
HFD2_k127_3987686_5 membrane - - - 0.000001225 60.0
HFD2_k127_4001636_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.05e-320 996.0
HFD2_k127_4001636_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 7.882e-233 728.0
HFD2_k127_4001636_10 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007127 248.0
HFD2_k127_4001636_11 heme a metabolic process K02259,K03110 - - 0.00000000000000000000000000000000000000000000005399 181.0
HFD2_k127_4001636_12 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000116 154.0
HFD2_k127_4001636_13 Protein of unknown function (DUF2393) - - - 0.0000000000000000000000000000000000000000378 156.0
HFD2_k127_4001636_14 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000382 160.0
HFD2_k127_4001636_15 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000004699 154.0
HFD2_k127_4001636_16 DinB family - - - 0.0000000000000000000001261 104.0
HFD2_k127_4001636_18 DinB superfamily - - - 0.00000000000001725 80.0
HFD2_k127_4001636_19 cheY-homologous receiver domain K02490 - - 0.00000000004804 68.0
HFD2_k127_4001636_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 577.0
HFD2_k127_4001636_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
HFD2_k127_4001636_4 PFAM aminotransferase class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 421.0
HFD2_k127_4001636_5 PFAM Formylglycine-generating sulfatase enzyme K12132,K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 414.0
HFD2_k127_4001636_6 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 371.0
HFD2_k127_4001636_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 354.0
HFD2_k127_4001636_8 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
HFD2_k127_4001636_9 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 339.0
HFD2_k127_4064114_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 9.397e-300 937.0
HFD2_k127_4064114_1 Dehydrogenase K00117 - 1.1.5.2 1.325e-281 881.0
HFD2_k127_4064114_2 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 378.0
HFD2_k127_4064114_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000004774 229.0
HFD2_k127_4064114_4 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000008455 182.0
HFD2_k127_4064114_5 - - - - 0.00000000000000000000000000000000000000000003116 174.0
HFD2_k127_4064114_6 - - - - 0.000000000000000000000000000000000006402 142.0
HFD2_k127_4064114_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000001803 78.0
HFD2_k127_4078120_0 lipopolysaccharide transport K22110 - - 0.0 1245.0
HFD2_k127_4078120_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 301.0
HFD2_k127_4078120_2 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
HFD2_k127_4078120_3 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005979 238.0
HFD2_k127_4078120_4 - - - - 0.000000000000000000000000000000003271 138.0
HFD2_k127_4078120_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000007836 125.0
HFD2_k127_4078120_6 - - - - 0.00000000000000000000000000001912 129.0
HFD2_k127_4078120_7 Small Multidrug Resistance protein - - - 0.0000000000000000000000000004954 122.0
HFD2_k127_4078120_8 Multidrug Resistance protein - - - 0.000000000000000000000000006465 115.0
HFD2_k127_4078120_9 - - - - 0.000000000005141 77.0
HFD2_k127_4087504_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.404e-245 764.0
HFD2_k127_4087504_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.344e-233 734.0
HFD2_k127_4087504_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 300.0
HFD2_k127_4087504_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
HFD2_k127_4087504_12 protein domain associated with - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006542 286.0
HFD2_k127_4087504_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004734 282.0
HFD2_k127_4087504_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
HFD2_k127_4087504_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000001508 228.0
HFD2_k127_4087504_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000004963 223.0
HFD2_k127_4087504_17 - - - - 0.0000000000000000000000000000000000000000000000000000000001094 217.0
HFD2_k127_4087504_18 - - - - 0.00000000000000000000000000000000000000000000000000000001526 203.0
HFD2_k127_4087504_19 - - - - 0.00000000000000000000000000000000000000000000000000000001783 209.0
HFD2_k127_4087504_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 595.0
HFD2_k127_4087504_20 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000000000005685 175.0
HFD2_k127_4087504_21 - - - - 0.000000000000000000000000000000000000005522 158.0
HFD2_k127_4087504_22 - - - - 0.0000000000000000000000000000000000009906 143.0
HFD2_k127_4087504_23 - - - - 0.00000000000000000000000000000000009778 138.0
HFD2_k127_4087504_24 - - - - 0.00000000000000000000000000000004195 129.0
HFD2_k127_4087504_25 - - - - 0.0000000000002536 78.0
HFD2_k127_4087504_26 PFAM Peptidase S45, penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 0.00000000329 69.0
HFD2_k127_4087504_27 Peptidase family M48 - - - 0.0008801 51.0
HFD2_k127_4087504_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 523.0
HFD2_k127_4087504_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 459.0
HFD2_k127_4087504_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 432.0
HFD2_k127_4087504_6 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 407.0
HFD2_k127_4087504_7 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 411.0
HFD2_k127_4087504_8 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
HFD2_k127_4087504_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 318.0
HFD2_k127_4103325_0 56kDa selenium binding protein (SBP56) K17285 - - 6.515e-241 750.0
HFD2_k127_4103325_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 7.657e-209 669.0
HFD2_k127_4103325_10 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 323.0
HFD2_k127_4103325_11 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 300.0
HFD2_k127_4103325_12 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004297 267.0
HFD2_k127_4103325_13 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004733 248.0
HFD2_k127_4103325_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002483 226.0
HFD2_k127_4103325_15 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
HFD2_k127_4103325_17 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000006485 205.0
HFD2_k127_4103325_18 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000001081 187.0
HFD2_k127_4103325_19 RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000000000000000000000000000003277 183.0
HFD2_k127_4103325_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 602.0
HFD2_k127_4103325_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002712 164.0
HFD2_k127_4103325_21 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000003154 152.0
HFD2_k127_4103325_22 - - - - 0.000000000000000000000000000000001331 143.0
HFD2_k127_4103325_23 Haem-binding domain - - - 0.00000000000000000000000001047 115.0
HFD2_k127_4103325_24 Transcriptional regulator - - - 0.00000000000000000000000005843 126.0
HFD2_k127_4103325_25 - - - - 0.00000000000000000000000008691 114.0
HFD2_k127_4103325_26 Membrane K09790 - - 0.0000000000000002599 91.0
HFD2_k127_4103325_27 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000003793 83.0
HFD2_k127_4103325_28 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000003028 81.0
HFD2_k127_4103325_29 SnoaL-like domain - - - 0.00000000001318 67.0
HFD2_k127_4103325_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 564.0
HFD2_k127_4103325_4 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 473.0
HFD2_k127_4103325_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 434.0
HFD2_k127_4103325_6 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 399.0
HFD2_k127_4103325_7 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 400.0
HFD2_k127_4103325_8 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 362.0
HFD2_k127_4103325_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 327.0
HFD2_k127_4115935_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 496.0
HFD2_k127_4115935_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 465.0
HFD2_k127_4115935_2 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 443.0
HFD2_k127_4115935_3 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 315.0
HFD2_k127_4115935_4 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
HFD2_k127_4115935_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
HFD2_k127_4115935_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000002735 189.0
HFD2_k127_4115935_7 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000000000006579 166.0
HFD2_k127_4115935_8 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000005568 108.0
HFD2_k127_4162445_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HFD2_k127_4162445_1 CO dehydrogenase flavoprotein C-terminal domain K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000005461 189.0
HFD2_k127_4162445_2 DinB family - - - 0.00000000000000000000000000000000000212 143.0
HFD2_k127_4162445_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000003032 122.0
HFD2_k127_4162445_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000004055 62.0
HFD2_k127_4162445_5 haloacid dehalogenase-like hydrolase - - - 0.0002602 51.0
HFD2_k127_4186391_0 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 489.0
HFD2_k127_4186391_1 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 342.0
HFD2_k127_4186391_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 329.0
HFD2_k127_4186391_3 SnoaL-like domain - - - 0.0000000000000000000000003016 117.0
HFD2_k127_4186391_4 - - - - 0.0000000000000000000004135 103.0
HFD2_k127_4186391_5 SnoaL-like domain - - - 0.000000000001113 79.0
HFD2_k127_4187570_0 Spermine/spermidine synthase domain - - - 2.973e-239 762.0
HFD2_k127_4187570_1 LVIVD repeat - - - 1.122e-231 722.0
HFD2_k127_4187570_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 297.0
HFD2_k127_4187570_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001327 295.0
HFD2_k127_4187570_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000001129 230.0
HFD2_k127_4187570_13 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004081 244.0
HFD2_k127_4187570_14 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000001667 215.0
HFD2_k127_4187570_15 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000002705 200.0
HFD2_k127_4187570_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000001706 166.0
HFD2_k127_4187570_17 Epoxide hydrolase N terminus K21159 - - 0.0000000000000000000000000000000000000003581 154.0
HFD2_k127_4187570_18 ASCH - - - 0.0000000000000000000000000000000000000128 146.0
HFD2_k127_4187570_19 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000008874 138.0
HFD2_k127_4187570_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 577.0
HFD2_k127_4187570_20 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000001219 136.0
HFD2_k127_4187570_21 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000002979 139.0
HFD2_k127_4187570_22 - - - - 0.000000000000000000000000000006262 136.0
HFD2_k127_4187570_23 - - - - 0.00000000000000000000000000004062 130.0
HFD2_k127_4187570_25 DinB superfamily - - - 0.0000000000000000000000112 108.0
HFD2_k127_4187570_26 - - - - 0.00000000000000000002993 91.0
HFD2_k127_4187570_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000008559 96.0
HFD2_k127_4187570_28 - - - - 0.00000004498 60.0
HFD2_k127_4187570_29 - - - - 0.00000006124 64.0
HFD2_k127_4187570_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 521.0
HFD2_k127_4187570_30 - - - - 0.0000001033 63.0
HFD2_k127_4187570_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 457.0
HFD2_k127_4187570_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 464.0
HFD2_k127_4187570_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 441.0
HFD2_k127_4187570_7 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 407.0
HFD2_k127_4187570_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 374.0
HFD2_k127_4187570_9 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 348.0
HFD2_k127_419271_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002615 213.0
HFD2_k127_419271_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000002188 136.0
HFD2_k127_4194035_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.878e-216 692.0
HFD2_k127_4194035_1 PFAM AMP-dependent synthetase K12508 - 6.2.1.34 1.653e-206 664.0
HFD2_k127_4194035_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
HFD2_k127_4194035_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 368.0
HFD2_k127_4194035_4 Thiolase, C-terminal domain K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
HFD2_k127_4194035_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002711 284.0
HFD2_k127_4194035_6 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000000000000000000000000000000000000000000004706 226.0
HFD2_k127_4194035_7 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000356 183.0
HFD2_k127_4232847_0 PFAM Amidohydrolase 3 - - - 2.19e-208 661.0
HFD2_k127_4232847_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 606.0
HFD2_k127_4232847_10 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000001648 186.0
HFD2_k127_4232847_11 - - - - 0.0000000000000000000000000000000006853 134.0
HFD2_k127_4232847_12 - - - - 0.00000000000000000000000000000003981 137.0
HFD2_k127_4232847_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000009409 137.0
HFD2_k127_4232847_14 - - - - 0.00000000000000000000000000001153 130.0
HFD2_k127_4232847_15 - - - - 0.00000000000000005013 81.0
HFD2_k127_4232847_16 Phage shock protein C, PspC K03973 - - 0.0000000000000001861 84.0
HFD2_k127_4232847_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000002683 76.0
HFD2_k127_4232847_18 - - - - 0.0000000001758 66.0
HFD2_k127_4232847_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 504.0
HFD2_k127_4232847_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 409.0
HFD2_k127_4232847_4 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 366.0
HFD2_k127_4232847_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 330.0
HFD2_k127_4232847_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 291.0
HFD2_k127_4232847_7 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007141 265.0
HFD2_k127_4247018_0 isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 324.0
HFD2_k127_4247018_2 proteolysis - - - 0.0000001093 63.0
HFD2_k127_4253462_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000003517 218.0
HFD2_k127_4321807_0 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 433.0
HFD2_k127_4321807_1 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 385.0
HFD2_k127_4321807_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 302.0
HFD2_k127_4321807_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002565 286.0
HFD2_k127_4321807_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
HFD2_k127_4321807_5 - - - - 0.00000000000000000000000000000000000000000000000000001904 198.0
HFD2_k127_4321807_6 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000005346 184.0
HFD2_k127_434090_0 AI-2E family transporter - - - 1.421e-234 739.0
HFD2_k127_434090_1 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 5.846e-199 637.0
HFD2_k127_434090_10 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000001709 113.0
HFD2_k127_434090_11 - - - - 0.0000000000000000000000008592 117.0
HFD2_k127_434090_13 Glycosyl transferase 4-like domain - - - 0.000000000000000001864 92.0
HFD2_k127_434090_14 Lactoylglutathione lyase - - - 0.0000000169 66.0
HFD2_k127_434090_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 497.0
HFD2_k127_434090_3 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 494.0
HFD2_k127_434090_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 430.0
HFD2_k127_434090_5 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 384.0
HFD2_k127_434090_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 346.0
HFD2_k127_434090_7 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 300.0
HFD2_k127_434090_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
HFD2_k127_434090_9 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000003012 132.0
HFD2_k127_4386441_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 453.0
HFD2_k127_4398512_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.423e-201 630.0
HFD2_k127_4398512_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 507.0
HFD2_k127_4398512_10 translation release factor activity - - - 0.000000000000000000006829 106.0
HFD2_k127_4398512_11 - - - - 0.000000000001159 79.0
HFD2_k127_4398512_12 Universal stress protein - - - 0.000000000002258 77.0
HFD2_k127_4398512_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 472.0
HFD2_k127_4398512_3 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 428.0
HFD2_k127_4398512_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 353.0
HFD2_k127_4398512_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001525 273.0
HFD2_k127_4398512_6 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000001355 230.0
HFD2_k127_4398512_7 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000455 224.0
HFD2_k127_4398512_8 - - - - 0.000000000000000000000000000000005262 137.0
HFD2_k127_4398512_9 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000001426 121.0
HFD2_k127_4403537_0 - - - - 9.251e-223 711.0
HFD2_k127_4403537_1 Dehydrogenase K00114 - 1.1.2.8 8.178e-217 690.0
HFD2_k127_4403537_10 - - - - 0.0000000000000000000000000674 121.0
HFD2_k127_4403537_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000005189 87.0
HFD2_k127_4403537_12 - - - - 0.0000000000007177 75.0
HFD2_k127_4403537_2 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 314.0
HFD2_k127_4403537_3 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
HFD2_k127_4403537_4 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
HFD2_k127_4403537_5 Glycerol-3-phosphate responsive antiterminator K02443 - - 0.00000000000000000000000000000000000000000000000000000000000002743 221.0
HFD2_k127_4403537_6 - - - - 0.000000000000000000000000000000000000000000000000001283 196.0
HFD2_k127_4403537_7 - - - - 0.00000000000000000000000000000000000002665 152.0
HFD2_k127_4403537_8 - - - - 0.000000000000000000000000000005251 132.0
HFD2_k127_4403537_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000001017 127.0
HFD2_k127_4425656_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 376.0
HFD2_k127_4425656_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000007989 133.0
HFD2_k127_4425656_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000001173 129.0
HFD2_k127_4425656_3 Belongs to the UPF0312 family - - - 0.00000001941 65.0
HFD2_k127_4438655_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 337.0
HFD2_k127_4438655_1 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HFD2_k127_4438655_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001292 244.0
HFD2_k127_4438655_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000001357 190.0
HFD2_k127_4438655_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000008582 171.0
HFD2_k127_4442174_0 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 347.0
HFD2_k127_4442174_1 flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000001783 181.0
HFD2_k127_4442174_2 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000009894 69.0
HFD2_k127_4442174_3 AAA domain K02282 - - 0.000001473 59.0
HFD2_k127_4447967_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 627.0
HFD2_k127_4447967_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 609.0
HFD2_k127_4447967_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000001526 186.0
HFD2_k127_4447967_3 - - - - 0.00000000000000000000000000002172 131.0
HFD2_k127_4461170_0 PFAM SMP-30 Gluconolaconase K08685,K14274 GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 450.0
HFD2_k127_4461170_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 360.0
HFD2_k127_4461170_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000003084 163.0
HFD2_k127_4461170_3 peroxiredoxin activity - - - 0.0000000000000000000000000000000005874 137.0
HFD2_k127_4462415_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1409.0
HFD2_k127_4462415_1 Domain of unknown function (DUF1998) K06877 - - 0.0 1171.0
HFD2_k127_4462415_10 PFAM YdjC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 336.0
HFD2_k127_4462415_11 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 320.0
HFD2_k127_4462415_12 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
HFD2_k127_4462415_13 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
HFD2_k127_4462415_14 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 299.0
HFD2_k127_4462415_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001751 296.0
HFD2_k127_4462415_16 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002986 287.0
HFD2_k127_4462415_17 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
HFD2_k127_4462415_18 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003904 267.0
HFD2_k127_4462415_19 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.000000000000000000000000000000000000000000000000000001007 207.0
HFD2_k127_4462415_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1035.0
HFD2_k127_4462415_20 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000945 183.0
HFD2_k127_4462415_21 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000001596 168.0
HFD2_k127_4462415_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000369 162.0
HFD2_k127_4462415_23 TIGRFAM death-on-curing family protein K07341 - - 0.0000000000000000000000000000000000000001143 153.0
HFD2_k127_4462415_24 PIN domain - - - 0.000000000000000000000000000000000000001004 150.0
HFD2_k127_4462415_25 Small Multidrug Resistance protein K03297,K11741 - - 0.000000000000000000000000001002 115.0
HFD2_k127_4462415_26 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000005627 91.0
HFD2_k127_4462415_27 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000004966 86.0
HFD2_k127_4462415_29 multi-organism process K03195 - - 0.000000000006645 76.0
HFD2_k127_4462415_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 444.0
HFD2_k127_4462415_31 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000232 53.0
HFD2_k127_4462415_32 - - - - 0.000002599 50.0
HFD2_k127_4462415_33 FtsX-like permease family - - - 0.00001196 50.0
HFD2_k127_4462415_4 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 375.0
HFD2_k127_4462415_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 373.0
HFD2_k127_4462415_6 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 374.0
HFD2_k127_4462415_7 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 365.0
HFD2_k127_4462415_8 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 345.0
HFD2_k127_4462415_9 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 366.0
HFD2_k127_4499792_0 Peptidase M16 inactive domain - - - 3.07e-200 645.0
HFD2_k127_4499792_1 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 424.0
HFD2_k127_4499792_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 321.0
HFD2_k127_4499792_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001617 256.0
HFD2_k127_4499792_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000004763 187.0
HFD2_k127_45182_0 Plasmid encoded RepA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 352.0
HFD2_k127_45182_1 DDE domain K07497 - - 0.0000000000000000000000000000000000000000000001381 170.0
HFD2_k127_45182_2 transposition - - - 0.0000000000000002379 84.0
HFD2_k127_4532967_0 Dehydrogenase K00114 - 1.1.2.8 6.647e-239 751.0
HFD2_k127_4532967_1 GMC oxidoreductase - - - 1.241e-237 747.0
HFD2_k127_4532967_10 Belongs to the IlvD Edd family K01687,K13875 - 4.2.1.25,4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
HFD2_k127_4532967_11 Alpha beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 321.0
HFD2_k127_4532967_12 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HFD2_k127_4532967_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
HFD2_k127_4532967_14 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000002098 262.0
HFD2_k127_4532967_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001248 245.0
HFD2_k127_4532967_16 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000001178 223.0
HFD2_k127_4532967_17 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000001249 204.0
HFD2_k127_4532967_19 - - - - 0.000000000000000000000000000001031 129.0
HFD2_k127_4532967_2 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 517.0
HFD2_k127_4532967_20 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000001394 118.0
HFD2_k127_4532967_21 Protein of unknown function (DUF2934) - - - 0.000006504 51.0
HFD2_k127_4532967_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 503.0
HFD2_k127_4532967_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HFD2_k127_4532967_5 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 434.0
HFD2_k127_4532967_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
HFD2_k127_4532967_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
HFD2_k127_4532967_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
HFD2_k127_4532967_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 370.0
HFD2_k127_4547512_0 4Fe-4S dicluster domain - - - 1.791e-282 882.0
HFD2_k127_4547512_1 Carboxyl transferase domain - - - 6.805e-265 827.0
HFD2_k127_4547512_10 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 403.0
HFD2_k127_4547512_11 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 394.0
HFD2_k127_4547512_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 383.0
HFD2_k127_4547512_13 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 385.0
HFD2_k127_4547512_14 peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 379.0
HFD2_k127_4547512_15 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 371.0
HFD2_k127_4547512_16 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 305.0
HFD2_k127_4547512_17 sequence-specific DNA binding K01174,K07720,K10778,K13529,K13652,K15051 - 2.1.1.63,3.1.31.1,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
HFD2_k127_4547512_18 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001316 236.0
HFD2_k127_4547512_19 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000000197 229.0
HFD2_k127_4547512_2 Domain of unknown function (DUF4139) - - - 7.83e-218 694.0
HFD2_k127_4547512_21 Protein of unknown function (DUF3738) - - - 0.0000000000000000000000000000000000000000000000000000000000005377 218.0
HFD2_k127_4547512_22 - - - - 0.00000000000000000000000000000000000000000000000009097 194.0
HFD2_k127_4547512_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002855 177.0
HFD2_k127_4547512_24 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000003731 154.0
HFD2_k127_4547512_25 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000009777 154.0
HFD2_k127_4547512_27 - - - - 0.000000000000000000000000001202 122.0
HFD2_k127_4547512_28 - - - - 0.00000000000000000000000003656 115.0
HFD2_k127_4547512_29 Putative regulatory protein - - - 0.00000000000000000000000004553 109.0
HFD2_k127_4547512_3 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 573.0
HFD2_k127_4547512_30 AI-2E family transporter - - - 0.00000000000000000000000166 108.0
HFD2_k127_4547512_31 Histidine kinase - - - 0.0000000000000008323 83.0
HFD2_k127_4547512_32 PFAM peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000002215 89.0
HFD2_k127_4547512_33 hydrolase activity - - - 0.00000000000003941 74.0
HFD2_k127_4547512_34 - - - - 0.00004006 56.0
HFD2_k127_4547512_35 - - - - 0.0003183 51.0
HFD2_k127_4547512_36 - - - - 0.0007445 47.0
HFD2_k127_4547512_37 DinB superfamily - - - 0.0009165 42.0
HFD2_k127_4547512_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 564.0
HFD2_k127_4547512_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 545.0
HFD2_k127_4547512_6 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 551.0
HFD2_k127_4547512_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 513.0
HFD2_k127_4547512_8 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 458.0
HFD2_k127_4547512_9 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 464.0
HFD2_k127_457788_0 Oligopeptide transporter OPT - - - 2.572e-283 884.0
HFD2_k127_457788_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 341.0
HFD2_k127_457788_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 326.0
HFD2_k127_457788_3 FES K03575 - - 0.0000000000000000000000000000000000000000000000000006326 190.0
HFD2_k127_457788_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000001488 95.0
HFD2_k127_4580282_0 PA domain - - - 1.713e-212 676.0
HFD2_k127_4580282_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 414.0
HFD2_k127_4585646_0 TonB dependent receptor - - - 0.0 1065.0
HFD2_k127_4585646_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.704e-258 819.0
HFD2_k127_4585646_10 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 316.0
HFD2_k127_4585646_11 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 283.0
HFD2_k127_4585646_12 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
HFD2_k127_4585646_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001552 243.0
HFD2_k127_4585646_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002101 216.0
HFD2_k127_4585646_16 PQQ-like domain K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000002849 208.0
HFD2_k127_4585646_17 - - - - 0.0000000000000000000000000000000000000000000000000007443 190.0
HFD2_k127_4585646_18 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000647 189.0
HFD2_k127_4585646_19 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000044 173.0
HFD2_k127_4585646_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.236e-240 753.0
HFD2_k127_4585646_20 Peptidase family M48 - - - 0.000000000000000000000000000000000000000001037 174.0
HFD2_k127_4585646_21 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000136 133.0
HFD2_k127_4585646_22 Protein of unknown function (DUF2934) - - - 0.000000000000000000001964 100.0
HFD2_k127_4585646_23 - - - - 0.000000000000000000004119 104.0
HFD2_k127_4585646_25 Sigma-54 interaction domain - - - 0.000000001128 61.0
HFD2_k127_4585646_26 Protein of unknown function (DUF1109) - - - 0.0001195 53.0
HFD2_k127_4585646_3 Sodium:solute symporter family - - - 4.073e-229 721.0
HFD2_k127_4585646_4 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.702e-218 685.0
HFD2_k127_4585646_5 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 566.0
HFD2_k127_4585646_6 Dehydrogenase K17760 - 1.1.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 505.0
HFD2_k127_4585646_7 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
HFD2_k127_4585646_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 405.0
HFD2_k127_4585646_9 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 355.0
HFD2_k127_4586336_0 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 603.0
HFD2_k127_4586336_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 308.0
HFD2_k127_4586336_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000004327 229.0
HFD2_k127_4586336_3 Phosphopantetheine attachment site - - - 0.000000000000000000004157 95.0
HFD2_k127_4586336_4 Acetyltransferase (GNAT) domain - - - 0.000000000000004123 78.0
HFD2_k127_4609767_0 Peptidase S46 - - - 7.855e-263 848.0
HFD2_k127_4609767_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.571e-234 730.0
HFD2_k127_4609767_10 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000004492 201.0
HFD2_k127_4609767_11 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000001713 174.0
HFD2_k127_4609767_12 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000006077 140.0
HFD2_k127_4609767_13 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000008065 87.0
HFD2_k127_4609767_14 Cytochrome C' - - - 0.0000002914 59.0
HFD2_k127_4609767_2 Response regulator receiver - - - 5.321e-206 648.0
HFD2_k127_4609767_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 493.0
HFD2_k127_4609767_4 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 470.0
HFD2_k127_4609767_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 466.0
HFD2_k127_4609767_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 366.0
HFD2_k127_4609767_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 346.0
HFD2_k127_4609767_8 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000005971 240.0
HFD2_k127_4609767_9 HDOD domain K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000005578 230.0
HFD2_k127_462124_0 DNA topological change K03168 - 5.99.1.2 1.73e-256 813.0
HFD2_k127_462124_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 456.0
HFD2_k127_462124_2 TIGRFAM luciferase family oxidoreductase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 423.0
HFD2_k127_462124_3 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 321.0
HFD2_k127_462124_4 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 288.0
HFD2_k127_462124_5 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007101 284.0
HFD2_k127_462124_6 - K02172 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 249.0
HFD2_k127_462124_7 - - - - 0.0000000000000000000000000000004955 132.0
HFD2_k127_462124_8 Protein of unknown function (DUF3738) K02172 - - 0.0000000000000000000000000003249 130.0
HFD2_k127_462124_9 cheY-homologous receiver domain - - - 0.0000000000002174 75.0
HFD2_k127_4636359_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 373.0
HFD2_k127_4636359_1 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 363.0
HFD2_k127_4636359_2 TonB C terminal - - - 0.00000000000000000000000000000131 132.0
HFD2_k127_4647505_0 tail sheath protein - - - 4.774e-286 904.0
HFD2_k127_4647505_1 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 518.0
HFD2_k127_4647505_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 495.0
HFD2_k127_4647505_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 463.0
HFD2_k127_4647505_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15242,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 357.0
HFD2_k127_4647505_5 Putative phage tail protein - - - 0.0000000000000000000000000000000000000000000000004316 183.0
HFD2_k127_4647505_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000002004 132.0
HFD2_k127_4647505_7 - - - - 0.0000000000000000000000000000002895 128.0
HFD2_k127_4663559_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 491.0
HFD2_k127_4663559_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 394.0
HFD2_k127_4663559_2 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 342.0
HFD2_k127_4663559_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004048 272.0
HFD2_k127_4663559_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HFD2_k127_4663559_5 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000001765 182.0
HFD2_k127_4663559_6 - - - - 0.0000000000000000000000000027 121.0
HFD2_k127_4663559_7 Protein conserved in bacteria - - - 0.00000004088 55.0
HFD2_k127_4663559_8 membrane - - - 0.00005384 48.0
HFD2_k127_466567_0 - - - - 5e-324 1005.0
HFD2_k127_466567_1 CAAX protease self-immunity K07052,K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 345.0
HFD2_k127_466567_2 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 324.0
HFD2_k127_466567_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002525 262.0
HFD2_k127_466567_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000009528 178.0
HFD2_k127_466567_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000001352 173.0
HFD2_k127_466567_6 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000002735 148.0
HFD2_k127_466567_7 RNA recognition motif - - - 0.000000000000000000000000000003796 123.0
HFD2_k127_466567_8 Methyltransferase FkbM domain - - - 0.000000000000000000000007994 112.0
HFD2_k127_466567_9 Acetyltransferase - - - 0.000000000000000166 87.0
HFD2_k127_4672909_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 481.0
HFD2_k127_4672909_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 429.0
HFD2_k127_4672909_2 histone H2A K63-linked ubiquitination K00925,K08884,K11894 - 2.7.11.1,2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 403.0
HFD2_k127_4672909_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
HFD2_k127_4672909_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001887 284.0
HFD2_k127_4672909_5 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
HFD2_k127_4672909_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000004706 230.0
HFD2_k127_4672909_7 - - - - 0.000000000000000000000000000000000000000000000000000003602 199.0
HFD2_k127_4682070_0 peptidyl-tyrosine sulfation - - - 2.062e-199 636.0
HFD2_k127_4682070_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 537.0
HFD2_k127_4682070_10 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000007729 163.0
HFD2_k127_4682070_11 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000001222 139.0
HFD2_k127_4682070_13 - - - - 0.0000000000000000000000000781 117.0
HFD2_k127_4682070_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000006083 107.0
HFD2_k127_4682070_15 - - - - 0.000000000000001173 91.0
HFD2_k127_4682070_16 DNA integration - - - 0.00000000002657 69.0
HFD2_k127_4682070_17 Cytochrome c K12263 - - 0.0000008154 56.0
HFD2_k127_4682070_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 520.0
HFD2_k127_4682070_3 Fumarase C C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 496.0
HFD2_k127_4682070_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 411.0
HFD2_k127_4682070_5 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 364.0
HFD2_k127_4682070_6 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 377.0
HFD2_k127_4682070_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000005659 228.0
HFD2_k127_4682070_9 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000001257 181.0
HFD2_k127_4685313_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 4.411e-312 968.0
HFD2_k127_4685313_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 4.076e-255 799.0
HFD2_k127_4685313_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 597.0
HFD2_k127_4685313_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 561.0
HFD2_k127_4685313_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
HFD2_k127_4685313_5 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000008688 209.0
HFD2_k127_4685313_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000001472 154.0
HFD2_k127_4696616_0 PFAM Carbohydrate kinase K00853 - 2.7.1.16 7.26e-246 769.0
HFD2_k127_4696616_1 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 530.0
HFD2_k127_4696616_2 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 470.0
HFD2_k127_4696616_3 PFAM Class II aldolase K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 325.0
HFD2_k127_4696616_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 287.0
HFD2_k127_4696616_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 279.0
HFD2_k127_4715147_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.475e-201 640.0
HFD2_k127_4715147_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 542.0
HFD2_k127_4715147_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 435.0
HFD2_k127_4715147_3 TIGRFAM TonB family K03832 - - 0.000000000000000000000000000001331 125.0
HFD2_k127_4715147_4 Preprotein translocase, YajC K03210 - - 0.00000000000000000000000002361 111.0
HFD2_k127_4743319_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.005e-292 908.0
HFD2_k127_4743319_1 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 353.0
HFD2_k127_4743319_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 340.0
HFD2_k127_4743319_3 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
HFD2_k127_4743319_4 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000000000000002925 142.0
HFD2_k127_4743319_5 - - - - 0.0000000000007549 70.0
HFD2_k127_4743319_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000007597 67.0
HFD2_k127_4745007_0 4Fe-4S dicluster domain K00184 - - 0.0 1046.0
HFD2_k127_4745007_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.28e-260 814.0
HFD2_k127_4745007_10 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000002036 180.0
HFD2_k127_4745007_11 PFAM cytochrome c oxidase, subunit III - - - 0.00000000000000000000000004442 111.0
HFD2_k127_4745007_2 PFAM Polysulphide reductase, NrfD - - - 3.898e-228 716.0
HFD2_k127_4745007_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
HFD2_k127_4745007_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 399.0
HFD2_k127_4745007_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 381.0
HFD2_k127_4745007_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 308.0
HFD2_k127_4745007_7 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 280.0
HFD2_k127_4745007_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
HFD2_k127_4745007_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000003263 188.0
HFD2_k127_4754731_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.848e-233 746.0
HFD2_k127_4754731_1 amino acid K03294 - - 8.369e-209 658.0
HFD2_k127_4754731_10 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 367.0
HFD2_k127_4754731_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HFD2_k127_4754731_12 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 285.0
HFD2_k127_4754731_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000137 267.0
HFD2_k127_4754731_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005821 279.0
HFD2_k127_4754731_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004178 251.0
HFD2_k127_4754731_16 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000003767 228.0
HFD2_k127_4754731_17 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000297 193.0
HFD2_k127_4754731_18 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000462 191.0
HFD2_k127_4754731_19 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000000000000000000000000001463 182.0
HFD2_k127_4754731_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.155e-200 646.0
HFD2_k127_4754731_20 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000009484 151.0
HFD2_k127_4754731_21 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000002911 145.0
HFD2_k127_4754731_22 SnoaL-like domain - - - 0.00000000000000000000000000000000001189 141.0
HFD2_k127_4754731_23 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000002541 132.0
HFD2_k127_4754731_24 - - - - 0.000000000000000000000000000003326 125.0
HFD2_k127_4754731_25 - - - - 0.00000000000000000001307 99.0
HFD2_k127_4754731_26 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000003432 101.0
HFD2_k127_4754731_28 - - - - 0.000000000003006 71.0
HFD2_k127_4754731_29 peptidyl-tyrosine sulfation - - - 0.00000000001709 77.0
HFD2_k127_4754731_3 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 620.0
HFD2_k127_4754731_4 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 538.0
HFD2_k127_4754731_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 511.0
HFD2_k127_4754731_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 414.0
HFD2_k127_4754731_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 392.0
HFD2_k127_4754731_8 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 400.0
HFD2_k127_4754731_9 PFAM glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 380.0
HFD2_k127_4849020_0 PFAM Pyrrolo-quinoline quinone K00114,K00117,K17760,K20937 - 1.1.2.8,1.1.5.11,1.1.5.2,1.1.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 419.0
HFD2_k127_4849020_1 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 406.0
HFD2_k127_4849020_2 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001916 264.0
HFD2_k127_4849020_3 Cytochrome c K17760 - 1.1.9.1 0.0000000000000000000000000000004435 125.0
HFD2_k127_4849363_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 548.0
HFD2_k127_4849363_1 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 434.0
HFD2_k127_4849363_10 - - - - 0.00000000000000000000000000001053 126.0
HFD2_k127_4849363_11 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000001415 88.0
HFD2_k127_4849363_12 Histidine kinase K07636 - 2.7.13.3 0.00000007741 57.0
HFD2_k127_4849363_13 Putative porin - - - 0.00001266 58.0
HFD2_k127_4849363_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 414.0
HFD2_k127_4849363_3 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
HFD2_k127_4849363_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD2_k127_4849363_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 350.0
HFD2_k127_4849363_6 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 293.0
HFD2_k127_4849363_7 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000004658 237.0
HFD2_k127_4849363_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000509 237.0
HFD2_k127_4849363_9 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000003321 139.0
HFD2_k127_4913840_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 549.0
HFD2_k127_4913840_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 488.0
HFD2_k127_4913840_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002165 254.0
HFD2_k127_4913840_3 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008312 245.0
HFD2_k127_4913840_4 - K02172 - - 0.00000000000000000000000000000000000000000000007959 179.0
HFD2_k127_4913840_5 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000009283 169.0
HFD2_k127_4913840_6 DoxX K15977 - - 0.00000000000000000000000000000000000000000003093 165.0
HFD2_k127_4913840_7 heat shock protein binding K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001262 167.0
HFD2_k127_4913840_8 - - - - 0.0000000000002022 72.0
HFD2_k127_4945995_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 438.0
HFD2_k127_4945995_1 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 411.0
HFD2_k127_4945995_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
HFD2_k127_4945995_3 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 296.0
HFD2_k127_4945995_4 proline dipeptidase activity K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 291.0
HFD2_k127_4945995_5 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
HFD2_k127_4945995_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000002914 229.0
HFD2_k127_4945995_7 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000395 85.0
HFD2_k127_4945995_8 NMT1-like family K02051 - - 0.0000000008532 71.0
HFD2_k127_4947851_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.618e-276 855.0
HFD2_k127_4947851_1 Belongs to the peptidase M48B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 429.0
HFD2_k127_4947851_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 352.0
HFD2_k127_4947851_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000005554 94.0
HFD2_k127_4979911_0 Involved in the tonB-independent uptake of proteins - - - 1.502e-215 700.0
HFD2_k127_4979911_1 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004384 244.0
HFD2_k127_4979911_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HFD2_k127_4979911_3 - - - - 0.0000000000000000000000000000007067 132.0
HFD2_k127_4979911_4 - - - - 0.00000000000000000214 87.0
HFD2_k127_4979911_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000007772 87.0
HFD2_k127_4979911_7 Papain family cysteine protease - - - 0.0000001973 57.0
HFD2_k127_4979911_8 Phage derived protein Gp49-like (DUF891) - - - 0.0000006247 53.0
HFD2_k127_4979911_9 Phage derived protein Gp49-like (DUF891) - - - 0.00000973 53.0
HFD2_k127_4991665_0 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 564.0
HFD2_k127_4991665_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 408.0
HFD2_k127_4991665_2 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 389.0
HFD2_k127_4991665_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 264.0
HFD2_k127_4991665_4 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
HFD2_k127_4991665_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
HFD2_k127_4991665_6 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000282 186.0
HFD2_k127_4991665_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000008682 116.0
HFD2_k127_4993141_0 chlorophyll binding - - - 4.043e-203 664.0
HFD2_k127_4993141_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000916 150.0
HFD2_k127_4993141_2 LppC putative lipoprotein - - - 0.00000000002181 68.0
HFD2_k127_4993141_3 DNA recombination - - - 0.00000000002561 76.0
HFD2_k127_4997986_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 450.0
HFD2_k127_4997986_1 membrane K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 315.0
HFD2_k127_4997986_2 Polycystin cation channel K08714 - - 0.00000000000000000000000000000000000000000000000000000000000002867 225.0
HFD2_k127_4997986_3 TspO/MBR family - - - 0.0000000000000000000000000000000000000000000000000000000105 203.0
HFD2_k127_5019559_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 537.0
HFD2_k127_5019559_1 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 288.0
HFD2_k127_5019559_2 Kinase, PfkB family K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000003034 256.0
HFD2_k127_5019559_3 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000000000000001696 103.0
HFD2_k127_5076826_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 509.0
HFD2_k127_5076826_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 449.0
HFD2_k127_5076826_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 354.0
HFD2_k127_5076826_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 335.0
HFD2_k127_5090105_0 Protein of unknown function (DUF3738) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 386.0
HFD2_k127_5090105_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 375.0
HFD2_k127_5090105_2 Alkylated DNA repair protein K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
HFD2_k127_5090105_3 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000003906 80.0
HFD2_k127_5090105_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000005706 59.0
HFD2_k127_5090105_5 - - - - 0.0000004042 59.0
HFD2_k127_5090105_6 - - - - 0.0000537 52.0
HFD2_k127_5090105_7 Agenet domain - - - 0.0002745 52.0
HFD2_k127_5137155_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 514.0
HFD2_k127_5137155_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 506.0
HFD2_k127_5137155_2 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 456.0
HFD2_k127_5137155_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 368.0
HFD2_k127_5137155_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 293.0
HFD2_k127_5137155_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
HFD2_k127_5157130_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 543.0
HFD2_k127_5157130_1 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 500.0
HFD2_k127_5157130_2 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 403.0
HFD2_k127_5157130_3 dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000000000002952 184.0
HFD2_k127_5157130_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000007389 109.0
HFD2_k127_5157727_0 Carboxypeptidase regulatory-like domain - - - 0.0 1163.0
HFD2_k127_5157727_1 - - - - 5.591e-284 887.0
HFD2_k127_5157727_2 - K02172 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 291.0
HFD2_k127_5157727_3 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000001518 289.0
HFD2_k127_5157727_4 Protein of unknown function (DUF3738) - - - 0.0000000000000000000000000000000000000000000000000000000007724 212.0
HFD2_k127_5157727_5 - - - - 0.000000000000000000000000000000000000000002836 169.0
HFD2_k127_5157727_6 - - - - 0.0000000000000000000000000000209 121.0
HFD2_k127_5159608_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.499e-233 729.0
HFD2_k127_5159608_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.577e-205 646.0
HFD2_k127_5159608_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
HFD2_k127_5159608_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000003594 205.0
HFD2_k127_5159608_12 - - - - 0.00000000000000000000000000000000000000000000000000000005471 205.0
HFD2_k127_5159608_13 - - - - 0.000000000000000000000000000000000000000000000000000007476 195.0
HFD2_k127_5159608_14 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000006773 184.0
HFD2_k127_5159608_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000417 181.0
HFD2_k127_5159608_16 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000003189 178.0
HFD2_k127_5159608_18 glyoxalase III activity - - - 0.00000000000000000003097 98.0
HFD2_k127_5159608_19 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000004721 87.0
HFD2_k127_5159608_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 592.0
HFD2_k127_5159608_20 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000002076 91.0
HFD2_k127_5159608_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000001402 88.0
HFD2_k127_5159608_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 511.0
HFD2_k127_5159608_4 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 471.0
HFD2_k127_5159608_5 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 434.0
HFD2_k127_5159608_6 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 420.0
HFD2_k127_5159608_7 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 333.0
HFD2_k127_5159608_8 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 313.0
HFD2_k127_5159608_9 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 301.0
HFD2_k127_5171958_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 582.0
HFD2_k127_5171958_1 'Molybdopterin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 488.0
HFD2_k127_5171958_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 474.0
HFD2_k127_5171958_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 361.0
HFD2_k127_5171958_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 330.0
HFD2_k127_5171958_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
HFD2_k127_5171958_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000001266 130.0
HFD2_k127_5185443_0 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 576.0
HFD2_k127_5185443_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000138 205.0
HFD2_k127_5185443_2 MmgE PrpD family protein - - - 0.00000000000000000000000000001498 120.0
HFD2_k127_518833_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 505.0
HFD2_k127_518833_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 393.0
HFD2_k127_518833_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
HFD2_k127_518833_3 Catechol dioxygenase N terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
HFD2_k127_518833_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 320.0
HFD2_k127_518833_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006677 288.0
HFD2_k127_518833_6 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000002882 124.0
HFD2_k127_5191961_0 pyrroloquinoline quinone binding - - - 1.507e-221 700.0
HFD2_k127_5191961_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 3.757e-214 694.0
HFD2_k127_5191961_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 594.0
HFD2_k127_5191961_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 479.0
HFD2_k127_5191961_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 465.0
HFD2_k127_5191961_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 472.0
HFD2_k127_5191961_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 417.0
HFD2_k127_5191961_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 379.0
HFD2_k127_5191961_8 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 301.0
HFD2_k127_5273043_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.273e-304 940.0
HFD2_k127_5273043_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 485.0
HFD2_k127_5273043_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
HFD2_k127_5315209_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1283.0
HFD2_k127_5315209_1 Uncharacterised protein family (UPF0182) K09118 - - 1.006e-277 873.0
HFD2_k127_5315209_2 tail sheath protein - - - 5.865e-264 841.0
HFD2_k127_5315209_3 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 492.0
HFD2_k127_5315209_4 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
HFD2_k127_5315209_5 addiction module antidote protein HigA - - - 0.00000000000000000000000000000000000000000007247 162.0
HFD2_k127_5315209_6 - - - - 0.0000000000000000000000000000000002656 137.0
HFD2_k127_5315209_7 - - - - 0.00000000000000000003235 95.0
HFD2_k127_532231_0 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 383.0
HFD2_k127_532231_1 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HFD2_k127_532231_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000002798 174.0
HFD2_k127_532231_3 GYD domain - - - 0.000000000000000000000000000000000000000236 152.0
HFD2_k127_532231_4 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.0000000000000000000000000006171 117.0
HFD2_k127_532510_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 3.517e-218 693.0
HFD2_k127_532510_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 599.0
HFD2_k127_532510_10 shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000001153 169.0
HFD2_k127_532510_11 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000003704 166.0
HFD2_k127_532510_12 PFAM TadE family protein - - - 0.0000000000000000004925 93.0
HFD2_k127_532510_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00001207 49.0
HFD2_k127_532510_14 Putative Flp pilus-assembly TadE/G-like - - - 0.0000276 56.0
HFD2_k127_532510_15 TadE-like protein - - - 0.0005736 49.0
HFD2_k127_532510_2 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 558.0
HFD2_k127_532510_3 FAD binding domain K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 538.0
HFD2_k127_532510_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 496.0
HFD2_k127_532510_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 445.0
HFD2_k127_532510_6 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 340.0
HFD2_k127_532510_7 ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 355.0
HFD2_k127_532510_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
HFD2_k127_532510_9 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000136 219.0
HFD2_k127_5335417_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.106e-222 697.0
HFD2_k127_5335417_1 Carboxypeptidase regulatory-like domain - - - 1.097e-217 717.0
HFD2_k127_5335417_2 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 522.0
HFD2_k127_5335417_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
HFD2_k127_5335417_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000001071 142.0
HFD2_k127_5335417_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000000788 128.0
HFD2_k127_5335417_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000002159 120.0
HFD2_k127_5335417_7 Protein tyrosine kinase - - - 0.0000000000002745 82.0
HFD2_k127_5346105_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1162.0
HFD2_k127_5346105_1 HD domain - - - 1.866e-245 788.0
HFD2_k127_5346105_2 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 315.0
HFD2_k127_5346105_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 320.0
HFD2_k127_5346105_4 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 294.0
HFD2_k127_5346105_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
HFD2_k127_5346105_6 metal-dependent hydrolase of the TIM-barrel fold K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000003135 261.0
HFD2_k127_5346105_7 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000005738 123.0
HFD2_k127_5346105_8 DinB family - - - 0.0000000000000001572 89.0
HFD2_k127_5375957_0 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 394.0
HFD2_k127_5375957_1 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000002852 219.0
HFD2_k127_5375957_2 TonB C terminal - - - 0.0000000000000000000000000000001264 125.0
HFD2_k127_5396939_0 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
HFD2_k127_5396939_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
HFD2_k127_5396939_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 321.0
HFD2_k127_5396939_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 313.0
HFD2_k127_5435817_0 SMP-30/Gluconolaconase/LRE-like region K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 440.0
HFD2_k127_5435817_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 362.0
HFD2_k127_5435817_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000062 176.0
HFD2_k127_5448631_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HFD2_k127_5448631_1 LssY C-terminus - - - 0.000000000000000000000000000000000000000352 162.0
HFD2_k127_5448631_2 methyltransferase - - - 0.000000000000000006655 98.0
HFD2_k127_5465492_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1305.0
HFD2_k127_5465492_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.209e-292 904.0
HFD2_k127_5465492_2 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
HFD2_k127_5465492_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
HFD2_k127_5465492_4 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000003068 201.0
HFD2_k127_5465492_5 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000000006588 153.0
HFD2_k127_5465492_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000001007 150.0
HFD2_k127_5465492_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00001077 47.0
HFD2_k127_5469009_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 379.0
HFD2_k127_5469009_1 Dehydrogenase K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 361.0
HFD2_k127_5469009_2 PFAM Cold-shock K03704 - - 0.0000000000000000000000000001474 116.0
HFD2_k127_5469009_3 Sporulation related domain - - - 0.0006664 49.0
HFD2_k127_5487711_0 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 345.0
HFD2_k127_5487711_1 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 306.0
HFD2_k127_5487711_3 Family of unknown function (DUF5372) - - - 0.00003134 48.0
HFD2_k127_5487711_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0005076 46.0
HFD2_k127_5510860_0 Bacterial protein of unknown function (DUF853) - - - 9.066e-231 723.0
HFD2_k127_5510860_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 453.0
HFD2_k127_5510860_2 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 457.0
HFD2_k127_5510860_3 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000006193 228.0
HFD2_k127_5533139_0 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 421.0
HFD2_k127_5533139_1 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000009626 201.0
HFD2_k127_5533139_2 Domain of unknown function (DUF4132) - - - 0.00003825 55.0
HFD2_k127_554316_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 548.0
HFD2_k127_554316_1 Cytochrome c - - - 0.000000000000001355 80.0
HFD2_k127_554316_2 Haem-degrading - - - 0.000000000000002438 83.0
HFD2_k127_5577330_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 515.0
HFD2_k127_5577330_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000003364 163.0
HFD2_k127_5578595_0 ankyrin repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 511.0
HFD2_k127_5578595_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 266.0
HFD2_k127_5578595_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000001108 191.0
HFD2_k127_5578595_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000008336 202.0
HFD2_k127_5578595_4 - - - - 0.000000000000000000000000000000000001187 145.0
HFD2_k127_5578595_5 - - - - 0.000000000000000000005482 100.0
HFD2_k127_5578595_6 Beta-lactamase - - - 0.000004154 56.0
HFD2_k127_5578595_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001619 56.0
HFD2_k127_5578595_8 - - - - 0.0001406 55.0
HFD2_k127_5584598_0 Zinc metalloprotease (Elastase) K01400,K01417,K01448,K20274 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.4.24.28,3.5.1.28 0.0 1181.0
HFD2_k127_5584598_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 1.309e-202 642.0
HFD2_k127_5584598_10 Protein of unknown function (DUF1266) - - - 0.0000000001707 74.0
HFD2_k127_5584598_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 407.0
HFD2_k127_5584598_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 339.0
HFD2_k127_5584598_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 337.0
HFD2_k127_5584598_5 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000002316 194.0
HFD2_k127_5584598_6 - - - - 0.0000000000000000000000000000000000000000003112 164.0
HFD2_k127_5584598_7 PFAM cytochrome c oxidase, subunit III - - - 0.00000000000000000000000000000000000002465 146.0
HFD2_k127_5584598_8 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000001153 150.0
HFD2_k127_5584598_9 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000002492 81.0
HFD2_k127_5604059_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 479.0
HFD2_k127_5604059_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 475.0
HFD2_k127_5604059_2 GMC oxidoreductase K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 432.0
HFD2_k127_5604059_3 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005256 254.0
HFD2_k127_5604059_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001307 223.0
HFD2_k127_5604059_5 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000005278 139.0
HFD2_k127_5604059_6 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000006193 99.0
HFD2_k127_5617954_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005385 269.0
HFD2_k127_5617954_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000005368 169.0
HFD2_k127_5617954_10 - - - - 0.000005085 57.0
HFD2_k127_5617954_11 Alpha/beta hydrolase family - - - 0.0000168 47.0
HFD2_k127_5617954_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000006932 151.0
HFD2_k127_5617954_4 - - - - 0.000000000000000000000000005301 122.0
HFD2_k127_5617954_5 - - - - 0.00000000000000004633 92.0
HFD2_k127_5617954_6 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000007637 82.0
HFD2_k127_5617954_7 - - - - 0.000000000000006783 81.0
HFD2_k127_5617954_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000001493 70.0
HFD2_k127_5617954_9 - - - - 0.0000001353 59.0
HFD2_k127_5622025_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.052e-205 659.0
HFD2_k127_5622025_1 PFAM natural resistance-associated macrophage protein - - - 2.826e-195 616.0
HFD2_k127_5622025_2 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 575.0
HFD2_k127_5622025_3 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 546.0
HFD2_k127_5622025_4 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000001019 187.0
HFD2_k127_5622025_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000002683 123.0
HFD2_k127_5622025_6 - - - - 0.0000000000000000000000000004002 122.0
HFD2_k127_5622025_7 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K03771 - 5.2.1.8 0.00000000000000000000000003346 119.0
HFD2_k127_5625853_0 PFAM ABC transporter - - - 4.628e-317 977.0
HFD2_k127_5625853_1 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
HFD2_k127_5625853_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
HFD2_k127_5625853_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003036 254.0
HFD2_k127_5665696_0 PFAM peptidase - - - 3.633e-222 695.0
HFD2_k127_5665696_1 virulence factor MVIN family protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
HFD2_k127_5688163_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 341.0
HFD2_k127_5688163_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000007903 246.0
HFD2_k127_5688163_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001119 199.0
HFD2_k127_5688163_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000003963 181.0
HFD2_k127_5696097_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
HFD2_k127_5696097_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 474.0
HFD2_k127_5696097_10 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000021 195.0
HFD2_k127_5696097_11 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000005382 165.0
HFD2_k127_5696097_12 Translation initiation factor 1A / IF-1 K02518 - - 0.000000000000000000000000000000000001862 140.0
HFD2_k127_5696097_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 452.0
HFD2_k127_5696097_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 431.0
HFD2_k127_5696097_4 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
HFD2_k127_5696097_5 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 368.0
HFD2_k127_5696097_6 PFAM Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
HFD2_k127_5696097_7 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005293 270.0
HFD2_k127_5696097_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 264.0
HFD2_k127_5696097_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003573 254.0
HFD2_k127_5731833_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 607.0
HFD2_k127_5731833_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 426.0
HFD2_k127_5731833_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000004517 222.0
HFD2_k127_5731833_3 - - - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
HFD2_k127_5731833_4 Haem-binding domain - - - 0.00000000000000000000000000000000000000000000008973 176.0
HFD2_k127_5731833_5 PFAM Transposase - - - 0.00000000000000000000003458 108.0
HFD2_k127_5731833_6 Resolvase, N terminal domain - - - 0.00000000000000000001447 102.0
HFD2_k127_5731833_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000001611 61.0
HFD2_k127_5731833_9 helix_turn_helix, mercury resistance - - - 0.0002609 48.0
HFD2_k127_5743401_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1048.0
HFD2_k127_5743401_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 494.0
HFD2_k127_5743401_2 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 392.0
HFD2_k127_5743401_3 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
HFD2_k127_5743401_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003538 214.0
HFD2_k127_5743401_5 CHRD domain - - - 0.000000000000000000000000000008649 125.0
HFD2_k127_5773192_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000001569 165.0
HFD2_k127_5773192_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000003534 87.0
HFD2_k127_5773192_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000203 82.0
HFD2_k127_5780785_0 amino acid - - - 0.0 1032.0
HFD2_k127_5780785_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 485.0
HFD2_k127_5780785_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000004375 196.0
HFD2_k127_5780785_11 regulatory protein, MerR - - - 0.0000000000000000000000000000000000000001493 154.0
HFD2_k127_5780785_12 - - - - 0.0000000000000000000000000001316 117.0
HFD2_k127_5780785_13 Histidine kinase K07675 - 2.7.13.3 0.0000000000001126 81.0
HFD2_k127_5780785_2 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 429.0
HFD2_k127_5780785_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
HFD2_k127_5780785_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 368.0
HFD2_k127_5780785_5 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 338.0
HFD2_k127_5780785_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 320.0
HFD2_k127_5780785_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005666 251.0
HFD2_k127_5780785_8 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000009535 227.0
HFD2_k127_5780785_9 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000000000000000000000002964 210.0
HFD2_k127_5802068_0 PFAM Glycosyl transferase family 2 - - - 5.749e-242 767.0
HFD2_k127_5802068_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 344.0
HFD2_k127_5802068_2 BON domain - - - 0.00000000000000000000000000000000000000000000000000000005064 205.0
HFD2_k127_5802068_3 - - - - 0.00000000000000000000002128 104.0
HFD2_k127_5848203_0 - - - - 0.0000000000000000000000000000000000000000006755 170.0
HFD2_k127_5848203_1 Amidohydrolase family - - - 0.00003284 48.0
HFD2_k127_5850218_0 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 560.0
HFD2_k127_5850218_1 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 491.0
HFD2_k127_5850218_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000003351 185.0
HFD2_k127_5850218_3 RNA recognition motif - - - 0.0000000000000000000000000000000000000000009308 163.0
HFD2_k127_5850218_4 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.0000000000000000000000000000000002082 133.0
HFD2_k127_5850218_5 - - - - 0.000000000000000000000000000000003233 132.0
HFD2_k127_5850218_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000008381 113.0
HFD2_k127_5850218_7 - - - - 0.0000000000000000000001958 98.0
HFD2_k127_5850218_8 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000002832 89.0
HFD2_k127_5921550_0 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 382.0
HFD2_k127_5921550_1 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 363.0
HFD2_k127_5921550_2 Tetratricopeptide repeat - - - 0.0000000000000000000000004007 117.0
HFD2_k127_5921550_3 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.0000000000000000005004 89.0
HFD2_k127_595042_0 PFAM SMP-30 Gluconolaconase - - - 6.81e-223 712.0
HFD2_k127_595042_1 SpoIVB peptidase S55 - - - 5.167e-212 682.0
HFD2_k127_595042_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.787e-198 625.0
HFD2_k127_595042_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 527.0
HFD2_k127_595042_4 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 420.0
HFD2_k127_595042_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890,K06878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 365.0
HFD2_k127_595042_6 - - - - 0.0000000000000000000000000000000000000000000000000108 184.0
HFD2_k127_595042_7 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000003058 171.0
HFD2_k127_595042_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000002354 57.0
HFD2_k127_5977504_0 2-methylcitrate dehydratase activity - - - 3.404e-213 673.0
HFD2_k127_5977504_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 562.0
HFD2_k127_5977504_2 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 490.0
HFD2_k127_5977504_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 472.0
HFD2_k127_5977504_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 388.0
HFD2_k127_5977504_5 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000003823 222.0
HFD2_k127_5977504_6 DinB superfamily - - - 0.0000000000000000000000000000000000003665 147.0
HFD2_k127_5977504_7 Transcriptional regulator K07979 - - 0.000000000000000000000000000000000009917 141.0
HFD2_k127_5988824_0 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
HFD2_k127_5988824_1 - - - - 0.000000000000000000000000000001406 139.0
HFD2_k127_600279_0 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 520.0
HFD2_k127_600279_1 carboxylic ester hydrolase activity K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001661 271.0
HFD2_k127_600279_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000008767 115.0
HFD2_k127_600279_3 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000003625 116.0
HFD2_k127_6009370_0 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 509.0
HFD2_k127_6009370_1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 405.0
HFD2_k127_6009370_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 413.0
HFD2_k127_6009370_3 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 402.0
HFD2_k127_6009370_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 324.0
HFD2_k127_6009370_5 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000004965 213.0
HFD2_k127_6009370_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000001244 164.0
HFD2_k127_6009370_7 energy transducer activity - - - 0.00000000000004117 79.0
HFD2_k127_6014833_0 amine dehydrogenase activity - - - 1.595e-272 871.0
HFD2_k127_6014833_1 PFAM type II secretion system protein E K02283 - - 4.218e-248 770.0
HFD2_k127_6014833_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
HFD2_k127_6014833_11 response regulator K02479,K07684,K07685 - - 0.00000000000000000000000000000000000000000000000000000000002939 213.0
HFD2_k127_6014833_12 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000000000000000000002557 139.0
HFD2_k127_6014833_13 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000007956 111.0
HFD2_k127_6014833_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000002397 106.0
HFD2_k127_6014833_15 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000002728 108.0
HFD2_k127_6014833_16 Glycosyltransferase family 87 - - - 0.00000003321 65.0
HFD2_k127_6014833_2 Aminotransferase class I and II K14261 - - 7.539e-209 656.0
HFD2_k127_6014833_3 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 510.0
HFD2_k127_6014833_4 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 437.0
HFD2_k127_6014833_5 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 425.0
HFD2_k127_6014833_6 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 415.0
HFD2_k127_6014833_7 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 411.0
HFD2_k127_6014833_8 type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 344.0
HFD2_k127_6014833_9 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 322.0
HFD2_k127_6037955_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 545.0
HFD2_k127_6037955_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 468.0
HFD2_k127_6037955_2 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 406.0
HFD2_k127_6037955_3 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 406.0
HFD2_k127_6037955_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 276.0
HFD2_k127_6037955_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002065 240.0
HFD2_k127_6037955_6 Amidohydrolase family - - - 0.00000000000001399 79.0
HFD2_k127_6075039_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 521.0
HFD2_k127_6075039_1 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000001206 231.0
HFD2_k127_6075039_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000009566 162.0
HFD2_k127_6075039_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000008271 77.0
HFD2_k127_6077141_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 529.0
HFD2_k127_6077141_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 420.0
HFD2_k127_6077141_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 415.0
HFD2_k127_6077141_3 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007164 278.0
HFD2_k127_6077141_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006101 257.0
HFD2_k127_6077141_5 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000001312 129.0
HFD2_k127_6095977_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.0000000000000000000000000000000000000000002066 169.0
HFD2_k127_6095977_1 Histidine kinase - - - 0.0000003626 54.0
HFD2_k127_6115063_0 TIGRFAM metabolite H symporter, major facilitator superfamily (MFS) K03288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 578.0
HFD2_k127_6115063_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 321.0
HFD2_k127_6115063_2 Glucose sorbosone K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 316.0
HFD2_k127_6115063_3 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000446 266.0
HFD2_k127_6115063_4 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
HFD2_k127_6115063_5 - - - - 0.000000000000000000000000000000000000000000000000000000000002535 219.0
HFD2_k127_6115063_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.00000000000000000000000000000000000000000000000009015 185.0
HFD2_k127_6115063_7 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000004354 134.0
HFD2_k127_6115063_8 - - - - 0.000000000000000443 87.0
HFD2_k127_6142316_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 397.0
HFD2_k127_6142316_3 TonB-dependent receptor K16090 - - 0.00000000000000000000000000000000000000000000000000007105 191.0
HFD2_k127_6142316_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000001072 118.0
HFD2_k127_6152173_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1494.0
HFD2_k127_6152173_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 384.0
HFD2_k127_6152173_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 368.0
HFD2_k127_6152173_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
HFD2_k127_6152173_4 Dehydrogenase K00114 - 1.1.2.8 0.000000000000000000000000000000008063 132.0
HFD2_k127_615701_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 327.0
HFD2_k127_615701_1 FecR protein - - - 0.00000000000000000000000000000000000000000000000000001097 199.0
HFD2_k127_615701_2 Domain of unknown function (DUF4870) - - - 0.000000000000000000000000005583 115.0
HFD2_k127_615701_3 - - - - 0.0000000000000000000000001412 113.0
HFD2_k127_6160006_0 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 535.0
HFD2_k127_6160006_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
HFD2_k127_6160006_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 300.0
HFD2_k127_6160006_3 Bacterial PH domain K08981 - - 0.0000000000000000000000000000000000000001003 153.0
HFD2_k127_6160006_4 - - - - 0.00000000000000000000000001927 118.0
HFD2_k127_6160006_5 - - - - 0.000000000000000001569 91.0
HFD2_k127_6161765_0 Iron-regulated membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 490.0
HFD2_k127_6161765_1 - - - - 0.000000000000000000321 93.0
HFD2_k127_6161765_2 - - - - 0.00000000000002527 78.0
HFD2_k127_6161765_3 Cytochrome oxidase assembly protein K02259 - - 0.00000000000003214 81.0
HFD2_k127_6161765_4 - - - - 0.000000005303 58.0
HFD2_k127_6161765_5 - - - - 0.00000001715 64.0
HFD2_k127_6162458_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 604.0
HFD2_k127_6162458_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 383.0
HFD2_k127_6162458_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 323.0
HFD2_k127_6162458_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000008578 177.0
HFD2_k127_6162458_5 - - - - 0.00000000000000000000008955 111.0
HFD2_k127_6162458_7 - - - - 0.0000001093 63.0
HFD2_k127_6164529_0 PFAM FAD linked oxidase - - - 8.414e-196 617.0
HFD2_k127_6164529_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 389.0
HFD2_k127_6164529_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 296.0
HFD2_k127_6164568_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 4.899e-252 793.0
HFD2_k127_6164568_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 568.0
HFD2_k127_6164568_2 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 381.0
HFD2_k127_6164568_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 334.0
HFD2_k127_6164568_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 325.0
HFD2_k127_6164568_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000008271 77.0
HFD2_k127_6164568_6 Plasmid stabilization K06218 - - 0.00000001873 58.0
HFD2_k127_6164568_7 PQQ-like domain K00114 - 1.1.2.8 0.000001078 59.0
HFD2_k127_6164568_8 - - - - 0.000001984 53.0
HFD2_k127_6206221_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.721e-256 800.0
HFD2_k127_6206221_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000003858 119.0
HFD2_k127_6227207_0 extracellular polysaccharide biosynthetic process K08252,K13661,K16554 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 305.0
HFD2_k127_6227207_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003871 267.0
HFD2_k127_6227399_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 8.433e-205 648.0
HFD2_k127_6227399_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 595.0
HFD2_k127_6227399_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 580.0
HFD2_k127_6227399_3 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 506.0
HFD2_k127_6227399_4 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 421.0
HFD2_k127_6227399_5 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004376 276.0
HFD2_k127_6227399_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000003013 183.0
HFD2_k127_6227399_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000002578 99.0
HFD2_k127_6227399_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001489 70.0
HFD2_k127_6228011_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.047e-285 885.0
HFD2_k127_6228011_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 2.31e-202 635.0
HFD2_k127_6228011_10 addiction module killer protein - - - 0.00000000000000000000000000000000000007116 147.0
HFD2_k127_6228011_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000001092 144.0
HFD2_k127_6228011_2 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 559.0
HFD2_k127_6228011_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 441.0
HFD2_k127_6228011_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
HFD2_k127_6228011_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 434.0
HFD2_k127_6228011_6 - K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 332.0
HFD2_k127_6228011_7 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 306.0
HFD2_k127_6228011_8 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000001571 227.0
HFD2_k127_6228011_9 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002364 222.0
HFD2_k127_6244230_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 583.0
HFD2_k127_6244230_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 540.0
HFD2_k127_6244230_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 439.0
HFD2_k127_6244230_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 327.0
HFD2_k127_6244230_4 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
HFD2_k127_6244230_5 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000009347 211.0
HFD2_k127_6245107_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 9.094e-247 787.0
HFD2_k127_6245107_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 324.0
HFD2_k127_6245107_2 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000002894 219.0
HFD2_k127_6245107_3 antisigma factor binding - - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD2_k127_6245107_4 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000001681 174.0
HFD2_k127_6245107_6 Alginate export - - - 0.00000000000000000000000000000000002562 143.0
HFD2_k127_6245107_7 Major Facilitator Superfamily K08191 - - 0.0000000000007335 76.0
HFD2_k127_6247999_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 521.0
HFD2_k127_6247999_1 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
HFD2_k127_6247999_2 - - - - 0.00000000000000000000000000000002571 142.0
HFD2_k127_6251518_0 Transposase K07491 - - 0.0000000000000000000000000000000000000000006853 164.0
HFD2_k127_6251518_1 Tetratricopeptide repeat - - - 0.00000000000007668 78.0
HFD2_k127_6251518_2 Transposase K07491 - - 0.000004537 50.0
HFD2_k127_6285763_0 PFAM General substrate transporter - - - 6.308e-209 656.0
HFD2_k127_6285763_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000001379 171.0
HFD2_k127_6285763_2 - - - - 0.000000001864 67.0
HFD2_k127_6285763_3 - - - - 0.000000002083 68.0
HFD2_k127_6294754_0 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 2.365e-196 619.0
HFD2_k127_6294754_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 595.0
HFD2_k127_6294754_2 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 570.0
HFD2_k127_6294754_3 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 371.0
HFD2_k127_6294754_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 340.0
HFD2_k127_6294754_5 Protein phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000805 261.0
HFD2_k127_6294754_6 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
HFD2_k127_6294754_7 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000000000000000002267 152.0
HFD2_k127_6294754_8 heat shock protein DnaJ K05516 - - 0.00000000004917 68.0
HFD2_k127_6294754_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000005835 61.0
HFD2_k127_6297370_0 peptidase - - - 0.000000000000000000000000000000000000000000000000005621 193.0
HFD2_k127_6297370_1 PepSY-associated TM region - - - 0.000000000000000000002809 104.0
HFD2_k127_6297370_2 carboxymuconolactone decarboxylase - - - 0.000000000001993 76.0
HFD2_k127_6297370_3 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.0000008941 59.0
HFD2_k127_6322764_0 unsaturated chondroitin disaccharide hydrolase activity K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 565.0
HFD2_k127_6322764_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 490.0
HFD2_k127_6322764_2 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 340.0
HFD2_k127_6322764_3 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001383 274.0
HFD2_k127_6322764_4 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001561 266.0
HFD2_k127_6322764_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007159 233.0
HFD2_k127_6322764_7 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000003843 216.0
HFD2_k127_6322764_8 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000002271 111.0
HFD2_k127_6322764_9 SnoaL-like domain K06893 - - 0.00000000000000000000000003387 113.0
HFD2_k127_6331280_0 PFAM Glucuronate isomerase K01812 - 5.3.1.12 2.153e-224 702.0
HFD2_k127_6331280_1 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 600.0
HFD2_k127_6331280_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 600.0
HFD2_k127_6331280_3 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 567.0
HFD2_k127_6331280_4 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 561.0
HFD2_k127_6331280_5 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000002896 181.0
HFD2_k127_6331280_6 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000486 141.0
HFD2_k127_6331280_7 Dehydrogenase - - - 0.000000000000000000000000000003452 126.0
HFD2_k127_6331280_8 lactate racemase activity K22373 - 5.1.2.1 0.000000000000001861 77.0
HFD2_k127_6331280_9 PQQ-like domain - - - 0.00000000006658 69.0
HFD2_k127_6348577_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 314.0
HFD2_k127_6348577_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000002529 88.0
HFD2_k127_6404219_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 340.0
HFD2_k127_6404219_1 - - - - 0.0000000000000000000000000000000000000000000000000000000006416 213.0
HFD2_k127_6404219_2 amine dehydrogenase activity - - - 0.0000000000000000515 82.0
HFD2_k127_6406563_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1308.0
HFD2_k127_6406563_1 Peptidase M14, carboxypeptidase A - - - 8.155e-261 812.0
HFD2_k127_6406563_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.051e-226 717.0
HFD2_k127_6406563_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 610.0
HFD2_k127_6406563_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000001159 226.0
HFD2_k127_640659_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 541.0
HFD2_k127_640659_1 - - - - 0.0000000000000000000000004006 112.0
HFD2_k127_640659_2 - - - - 0.000000000000000000000001148 108.0
HFD2_k127_640659_3 - - - - 0.00000000000000000001882 102.0
HFD2_k127_6444260_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 415.0
HFD2_k127_6444260_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
HFD2_k127_6444260_2 Metal binding domain of Ada K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 319.0
HFD2_k127_6444260_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000005207 144.0
HFD2_k127_6444260_4 oxidoreductase activity - - - 0.0000000000000000000000000000000002779 153.0
HFD2_k127_6460755_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 460.0
HFD2_k127_6460755_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004178 251.0
HFD2_k127_6460755_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000003126 219.0
HFD2_k127_6460755_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000006211 99.0
HFD2_k127_6469915_0 protein kinase activity K06915 - - 1.087e-272 858.0
HFD2_k127_6469915_1 cobalamin-transporting ATPase activity - - - 3.303e-214 689.0
HFD2_k127_6469915_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 554.0
HFD2_k127_6469915_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
HFD2_k127_6469915_4 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000004128 235.0
HFD2_k127_6469915_5 mitochondrion morphogenesis K06195 - - 0.0000000000000000000000000000000000000000000000000000000006362 203.0
HFD2_k127_6469915_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000001589 189.0
HFD2_k127_6486560_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 8.486e-297 922.0
HFD2_k127_6486560_1 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 4.583e-295 915.0
HFD2_k127_6486560_2 PQQ-like domain K00114 - 1.1.2.8 5.557e-240 752.0
HFD2_k127_6486560_3 PFAM Major Facilitator Superfamily K08191 - - 5.533e-229 713.0
HFD2_k127_6486560_4 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 1.386e-224 706.0
HFD2_k127_6486560_5 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 5.345e-200 634.0
HFD2_k127_6486560_6 Belongs to the xylose isomerase family K01805 - 5.3.1.5 2.572e-199 627.0
HFD2_k127_6486560_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
HFD2_k127_6486560_8 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000001126 193.0
HFD2_k127_6486560_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000006132 53.0
HFD2_k127_6509924_0 - - - - 0.0000000000000000000000000006181 129.0
HFD2_k127_6509924_1 - - - - 0.000000000000000005377 91.0
HFD2_k127_6509924_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000004223 85.0
HFD2_k127_6520592_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 6.393e-286 889.0
HFD2_k127_6520592_1 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 5.893e-265 857.0
HFD2_k127_6520592_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 499.0
HFD2_k127_6520592_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 262.0
HFD2_k127_6520592_4 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000001139 207.0
HFD2_k127_6520592_5 Displays ATPase and GTPase activities K06958 - - 0.000000000000001536 76.0
HFD2_k127_6520592_7 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00001179 52.0
HFD2_k127_6534860_0 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 565.0
HFD2_k127_6534860_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 299.0
HFD2_k127_6534860_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006108 260.0
HFD2_k127_6534860_3 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000452 246.0
HFD2_k127_6534860_4 - - - - 0.000000000000000000000000000000000953 140.0
HFD2_k127_6534860_6 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0000000000152 66.0
HFD2_k127_6544213_0 DNA topological change K03168 - 5.99.1.2 2.982e-235 751.0
HFD2_k127_6544213_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 331.0
HFD2_k127_6544213_2 Ankyrin repeat domain protein - - - 0.0000001494 56.0
HFD2_k127_6545800_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 8.579e-290 925.0
HFD2_k127_6545800_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.596e-281 884.0
HFD2_k127_6545800_10 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008159 267.0
HFD2_k127_6545800_11 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000004648 131.0
HFD2_k127_6545800_12 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000000008651 125.0
HFD2_k127_6545800_15 photosynthesis K02656 - - 0.000000000000000000000001029 108.0
HFD2_k127_6545800_16 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000429 97.0
HFD2_k127_6545800_2 Histidine kinase internal region K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 471.0
HFD2_k127_6545800_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 445.0
HFD2_k127_6545800_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 403.0
HFD2_k127_6545800_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 389.0
HFD2_k127_6545800_6 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 392.0
HFD2_k127_6545800_7 DNA integration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 381.0
HFD2_k127_6545800_8 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 358.0
HFD2_k127_6545800_9 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 306.0
HFD2_k127_6568163_0 Hpt domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 600.0
HFD2_k127_6568163_1 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 463.0
HFD2_k127_6568163_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 271.0
HFD2_k127_6568163_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000004111 75.0
HFD2_k127_6576334_0 DDE superfamily endonuclease - - - 0.0000000000000000000002075 102.0
HFD2_k127_6576334_1 FtsX-like permease family - - - 0.0000000000658 73.0
HFD2_k127_6576334_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000007156 57.0
HFD2_k127_6588290_0 DNA topological change K03168 - 5.99.1.2 1.449e-211 690.0
HFD2_k127_6588290_1 Acyl transferase domain in polyketide synthase (PKS) enzymes. K16129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 533.0
HFD2_k127_6588290_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000003366 65.0
HFD2_k127_6588290_11 - - - - 0.0000000004021 71.0
HFD2_k127_6588290_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 481.0
HFD2_k127_6588290_3 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 364.0
HFD2_k127_6588290_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001687 270.0
HFD2_k127_6588290_5 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004473 267.0
HFD2_k127_6588290_6 - - - - 0.0000000000000000000000000000000000000000000000001701 191.0
HFD2_k127_6588290_7 - - - - 0.000000000000000000000000000000000000002318 157.0
HFD2_k127_6588290_8 - - - - 0.00000000000000000000006298 112.0
HFD2_k127_6588290_9 - - - - 0.0000000000000000000561 94.0
HFD2_k127_6613389_0 Peptidase M1, membrane alanine aminopeptidase - - - 5.912e-249 784.0
HFD2_k127_6613389_1 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 580.0
HFD2_k127_6613389_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 490.0
HFD2_k127_6613389_3 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 436.0
HFD2_k127_6613389_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 407.0
HFD2_k127_6613389_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
HFD2_k127_6613389_6 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 351.0
HFD2_k127_6613389_7 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000005756 238.0
HFD2_k127_6613389_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000006724 207.0
HFD2_k127_6617884_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 563.0
HFD2_k127_6617884_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 483.0
HFD2_k127_6617884_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 466.0
HFD2_k127_6617884_3 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 317.0
HFD2_k127_6617884_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 300.0
HFD2_k127_6617884_5 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000254 196.0
HFD2_k127_6617884_6 ABC-2 family transporter protein K01992 - - 0.000000000004254 67.0
HFD2_k127_6632698_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 324.0
HFD2_k127_6632698_1 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000001144 169.0
HFD2_k127_6632698_2 Inner membrane component of T3SS, cytoplasmic domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.0000000000004392 73.0
HFD2_k127_6632698_3 ATPase AAA-2 domain protein - - - 0.00000001563 68.0
HFD2_k127_6650139_0 Putative glucoamylase - - - 0.0 1628.0
HFD2_k127_6650139_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 613.0
HFD2_k127_6650139_2 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 336.0
HFD2_k127_6650139_4 Phosphotransferase enzyme family K07028 - - 0.00006199 55.0
HFD2_k127_6660866_0 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 370.0
HFD2_k127_6660866_1 methyltransferase activity K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 352.0
HFD2_k127_6660866_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 317.0
HFD2_k127_6660866_3 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001123 288.0
HFD2_k127_6660866_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005072 263.0
HFD2_k127_6660866_5 - - - - 0.00000000000000000000000000000000000000000000000000000235 198.0
HFD2_k127_6660866_6 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.00000000000000000000000000003355 123.0
HFD2_k127_6663399_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1393.0
HFD2_k127_6663399_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000849 276.0
HFD2_k127_6663399_2 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000000000004636 138.0
HFD2_k127_6663399_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000008798 109.0
HFD2_k127_6663399_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000001685 104.0
HFD2_k127_6669597_0 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 1.799e-229 718.0
HFD2_k127_6669597_1 Transaldolase/Fructose-6-phosphate aldolase K00616,K13810 - 2.2.1.2,5.3.1.9 9.741e-219 691.0
HFD2_k127_6669597_2 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 548.0
HFD2_k127_6669597_3 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 489.0
HFD2_k127_6669597_4 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
HFD2_k127_6669597_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 335.0
HFD2_k127_6669597_6 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 291.0
HFD2_k127_6669597_7 - - - - 0.00000000000000000000000000001346 126.0
HFD2_k127_6669597_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000009097 116.0
HFD2_k127_6669597_9 Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge K00574 - 2.1.1.79 0.0000000000003078 74.0
HFD2_k127_6714565_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 1.392e-309 955.0
HFD2_k127_6714565_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 8.602e-238 743.0
HFD2_k127_6714565_10 YjbR - - - 0.0000000000000000000000000000002005 127.0
HFD2_k127_6714565_11 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000007485 111.0
HFD2_k127_6714565_12 Putative restriction endonuclease - - - 0.00000000000000000000000002397 116.0
HFD2_k127_6714565_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.797e-216 684.0
HFD2_k127_6714565_3 Heavy metal translocating P-type atpase - - - 1.452e-208 666.0
HFD2_k127_6714565_4 von Willebrand factor (vWF) type A domain K07114 - - 2.092e-201 633.0
HFD2_k127_6714565_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 490.0
HFD2_k127_6714565_6 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 363.0
HFD2_k127_6714565_7 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000009455 215.0
HFD2_k127_6714565_8 phosphatase activity K07025,K20862,K20866 - 3.1.3.10,3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000001315 164.0
HFD2_k127_6714565_9 Universal stress protein - - - 0.00000000000000000000000000000000000000003824 164.0
HFD2_k127_6765893_0 glutamine synthetase K01915 - 6.3.1.2 2.63e-273 848.0
HFD2_k127_6765893_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 476.0
HFD2_k127_6790116_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 6.159e-308 970.0
HFD2_k127_6790116_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 1.716e-266 827.0
HFD2_k127_6790116_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 372.0
HFD2_k127_6790116_3 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000002647 183.0
HFD2_k127_6790116_4 Short-chain dehydrogenase reductase SDR - - - 0.0000005539 52.0
HFD2_k127_6792127_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 585.0
HFD2_k127_6792127_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000007966 209.0
HFD2_k127_6792127_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000003734 81.0
HFD2_k127_6792600_1 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 404.0
HFD2_k127_6792600_2 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 340.0
HFD2_k127_6792600_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
HFD2_k127_6792600_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000007292 255.0
HFD2_k127_6792600_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000003521 239.0
HFD2_k127_6792600_6 - - - - 0.0000000000000000000000000000000000001684 146.0
HFD2_k127_6792600_7 peptidyl-tyrosine sulfation K13992 - - 0.000000000000000000006001 100.0
HFD2_k127_6792600_8 CHRD domain containing protein - - - 0.000000414 58.0
HFD2_k127_6792600_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00004194 54.0
HFD2_k127_6806641_0 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 608.0
HFD2_k127_6813329_0 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000007812 213.0
HFD2_k127_6813329_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000001734 207.0
HFD2_k127_6813329_2 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000003581 188.0
HFD2_k127_6813329_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000466 196.0
HFD2_k127_6813329_4 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000002216 160.0
HFD2_k127_6813329_5 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000002341 118.0
HFD2_k127_6813329_6 - - - - 0.00000000000000000000000009384 119.0
HFD2_k127_6813329_7 - - - - 0.00000000000000001197 94.0
HFD2_k127_6813329_8 - - - - 0.000000000000005491 79.0
HFD2_k127_6813329_9 - - - - 0.000006619 57.0
HFD2_k127_6855987_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 604.0
HFD2_k127_6855987_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 327.0
HFD2_k127_6855987_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006671 233.0
HFD2_k127_6855987_3 DnaJ molecular chaperone homology domain - - - 0.0004557 49.0
HFD2_k127_6881751_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.012e-195 623.0
HFD2_k127_6881751_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 424.0
HFD2_k127_6881751_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 317.0
HFD2_k127_6881751_3 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 311.0
HFD2_k127_6881751_4 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 295.0
HFD2_k127_6881751_5 - - - - 0.0000000000000000000000000000000000000000000000000004004 192.0
HFD2_k127_6881751_6 Tetratricopeptide repeat - - - 0.000000000000000001892 85.0
HFD2_k127_6881751_7 GAF domain K08968 - 1.8.4.14 0.000000000000004491 85.0
HFD2_k127_6912735_0 MacB-like periplasmic core domain K02004 - - 5.939e-212 665.0
HFD2_k127_6912735_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 554.0
HFD2_k127_6912735_10 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000002177 200.0
HFD2_k127_6912735_11 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000004532 167.0
HFD2_k127_6912735_12 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000001991 159.0
HFD2_k127_6912735_13 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000002664 132.0
HFD2_k127_6912735_14 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000002423 90.0
HFD2_k127_6912735_15 - - - - 0.000004104 59.0
HFD2_k127_6912735_16 cell wall anchor domain - - - 0.0005366 53.0
HFD2_k127_6912735_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 532.0
HFD2_k127_6912735_3 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 490.0
HFD2_k127_6912735_4 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 417.0
HFD2_k127_6912735_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 391.0
HFD2_k127_6912735_6 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 367.0
HFD2_k127_6912735_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
HFD2_k127_6912735_8 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HFD2_k127_6912735_9 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000009113 231.0
HFD2_k127_6914436_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001468 251.0
HFD2_k127_6914436_1 beta-acetyl hexosaminidase like K12373 - 3.2.1.52 0.0001176 55.0
HFD2_k127_6914436_2 - - - - 0.0009153 44.0
HFD2_k127_6933176_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 486.0
HFD2_k127_6933176_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000001857 156.0
HFD2_k127_6949709_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 4.961e-242 756.0
HFD2_k127_6949709_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 411.0
HFD2_k127_6949709_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
HFD2_k127_6949709_3 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000001098 227.0
HFD2_k127_6949709_4 2-oxopent-4-enoate hydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006022 225.0
HFD2_k127_6949709_5 - - - - 0.000000000000000000000000000000000000000000000000000002977 201.0
HFD2_k127_6949709_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000008778 162.0
HFD2_k127_6959157_0 MacB-like periplasmic core domain - - - 5.269e-265 832.0
HFD2_k127_6959157_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 588.0
HFD2_k127_6959157_2 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 460.0
HFD2_k127_6959157_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 432.0
HFD2_k127_6959157_4 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 416.0
HFD2_k127_6959157_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002047 278.0
HFD2_k127_6959157_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 279.0
HFD2_k127_6959157_7 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000001467 176.0
HFD2_k127_6959157_8 Histidine kinase - - - 0.000001984 53.0
HFD2_k127_7027288_0 PFAM Transposase, IS4-like - - - 0.000000000000000001822 98.0
HFD2_k127_7027288_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000001725 72.0
HFD2_k127_7027288_2 - - - - 0.0000000003696 65.0
HFD2_k127_7049533_0 Histidine kinase - - - 0.0 1247.0
HFD2_k127_7049533_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 575.0
HFD2_k127_7049533_10 - - - - 0.000000000000000000001089 100.0
HFD2_k127_7049533_11 - - - - 0.000000000000000000001732 97.0
HFD2_k127_7049533_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000004603 88.0
HFD2_k127_7049533_13 PKD domain containing protein K01179 - 3.2.1.4 0.00000000000000005785 90.0
HFD2_k127_7049533_2 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 507.0
HFD2_k127_7049533_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 345.0
HFD2_k127_7049533_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000003136 218.0
HFD2_k127_7049533_5 - - - - 0.0000000000000000000000000000000000000000001377 166.0
HFD2_k127_7049533_6 - - - - 0.00000000000000000000000000000000000000718 153.0
HFD2_k127_7049533_7 zinc ion binding K06204 - - 0.0000000000000000000000000008242 116.0
HFD2_k127_7049533_8 Stage II sporulation protein E - - - 0.00000000000000000000000008868 121.0
HFD2_k127_7086696_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
HFD2_k127_7086696_1 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 370.0
HFD2_k127_7086696_2 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000002218 182.0
HFD2_k127_7086696_3 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.000000000007807 69.0
HFD2_k127_7092071_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 306.0
HFD2_k127_7092071_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
HFD2_k127_7092071_2 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0000000000000000000000000000001322 135.0
HFD2_k127_7092071_3 - - - - 0.00000002322 58.0
HFD2_k127_7095401_0 GTP-binding protein TypA K06207 - - 3.549e-267 828.0
HFD2_k127_7095401_1 RNA polymerase sigma-54 factor K03092 - - 1.615e-221 698.0
HFD2_k127_7095401_10 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000005606 143.0
HFD2_k127_7095401_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000006487 140.0
HFD2_k127_7095401_12 - - - - 0.0000000000000000000000000002686 117.0
HFD2_k127_7095401_13 Bacterial protein of unknown function (DUF882) - - - 0.0000000000001128 76.0
HFD2_k127_7095401_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 572.0
HFD2_k127_7095401_3 Domain of unknown function (DUF3520) K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 546.0
HFD2_k127_7095401_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 370.0
HFD2_k127_7095401_5 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 329.0
HFD2_k127_7095401_6 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 299.0
HFD2_k127_7095401_7 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009403 243.0
HFD2_k127_7095401_8 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000004982 178.0
HFD2_k127_7095401_9 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000003467 169.0
HFD2_k127_7102622_0 MacB-like periplasmic core domain K02004 - - 1.25e-245 784.0
HFD2_k127_7102622_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 490.0
HFD2_k127_7102622_10 PFAM Redoxin - - - 0.000000000000000000000000000000000000000000000006345 177.0
HFD2_k127_7102622_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000001236 158.0
HFD2_k127_7102622_12 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000004657 143.0
HFD2_k127_7102622_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000355 139.0
HFD2_k127_7102622_14 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000002875 133.0
HFD2_k127_7102622_16 - - - - 0.00000000000000000000001952 107.0
HFD2_k127_7102622_17 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000002198 79.0
HFD2_k127_7102622_18 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000002311 61.0
HFD2_k127_7102622_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HFD2_k127_7102622_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
HFD2_k127_7102622_4 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001972 274.0
HFD2_k127_7102622_5 NmrA-like family K07118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
HFD2_k127_7102622_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000004318 235.0
HFD2_k127_7102622_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
HFD2_k127_7102622_8 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000009671 222.0
HFD2_k127_7102622_9 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000002847 199.0
HFD2_k127_7110880_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503,K13950 - 2.6.1.85,4.1.3.27 0.0 1026.0
HFD2_k127_7110880_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 580.0
HFD2_k127_7110880_2 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 459.0
HFD2_k127_7110880_3 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 421.0
HFD2_k127_7110880_4 Major Facilitator Superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 313.0
HFD2_k127_7110880_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 297.0
HFD2_k127_7110880_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003277 261.0
HFD2_k127_7110880_7 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
HFD2_k127_7114544_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 612.0
HFD2_k127_7149720_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.96e-206 672.0
HFD2_k127_7149720_1 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000001077 214.0
HFD2_k127_7149720_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000004875 196.0
HFD2_k127_7149720_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000001678 200.0
HFD2_k127_7149720_4 Protein of unknown function (DUF507) K09804 - - 0.00000000002393 64.0
HFD2_k127_7151034_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 533.0
HFD2_k127_7151034_1 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 506.0
HFD2_k127_7151034_10 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000007324 154.0
HFD2_k127_7151034_2 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 308.0
HFD2_k127_7151034_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
HFD2_k127_7151034_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000001894 204.0
HFD2_k127_7151034_5 ATP-dependent protease La (LON) substrate-binding domain - - - 0.00000000000000000000000000000000000000000000000000000001602 203.0
HFD2_k127_7151034_6 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000004029 201.0
HFD2_k127_7151034_7 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000008771 199.0
HFD2_k127_7151034_8 protocatechuate 3,4-dioxygenase activity K02014 - - 0.000000000000000000000000000000000000000000000000002277 203.0
HFD2_k127_7151034_9 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000004597 169.0
HFD2_k127_7173589_0 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 427.0
HFD2_k127_7173589_1 FAD binding domain K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 404.0
HFD2_k127_7173589_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 404.0
HFD2_k127_7173589_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000009082 186.0
HFD2_k127_7173589_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000002677 164.0
HFD2_k127_7173589_5 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000007475 148.0
HFD2_k127_7173589_6 ankyrin repeat K15503 - - 0.0005817 44.0
HFD2_k127_7195273_0 DNA-K related protein - - - 0.0 1187.0
HFD2_k127_7195273_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 1.623e-219 689.0
HFD2_k127_7195273_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000008407 188.0
HFD2_k127_7195273_11 Rieske [2Fe-2S] domain K03886 - - 0.000000000000000000000000000000000000000000001024 170.0
HFD2_k127_7195273_12 SET domain K07117 - - 0.00000000000000000000000000000000000000000001427 171.0
HFD2_k127_7195273_2 signal transduction histidine kinase - - - 1.444e-216 696.0
HFD2_k127_7195273_3 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 600.0
HFD2_k127_7195273_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 400.0
HFD2_k127_7195273_5 von Willebrand factor, type A K07114,K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 367.0
HFD2_k127_7195273_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 332.0
HFD2_k127_7195273_7 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000003006 206.0
HFD2_k127_7195273_8 transporter - - - 0.0000000000000000000000000000000000000000000000000000002249 202.0
HFD2_k127_7195273_9 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000000000000813 197.0
HFD2_k127_7202857_0 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 464.0
HFD2_k127_7202857_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 316.0
HFD2_k127_7202857_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002465 281.0
HFD2_k127_7202857_3 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000000000006781 126.0
HFD2_k127_7202857_4 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.000000000000000000000000009148 111.0
HFD2_k127_7202857_5 Beta-lactamase - - - 0.0000000000000000269 92.0
HFD2_k127_7202857_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000004773 76.0
HFD2_k127_7205141_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 600.0
HFD2_k127_7205141_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 362.0
HFD2_k127_7205141_2 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 301.0
HFD2_k127_7210139_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 600.0
HFD2_k127_7210139_1 nitrite transmembrane transporter activity K08177 - - 0.000000000000000000000000000000000000000000000000000000443 196.0
HFD2_k127_7210139_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000009391 177.0
HFD2_k127_7236330_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2526.0
HFD2_k127_7236330_1 Domain of unknown function (DUF5117) - - - 1.916e-317 994.0
HFD2_k127_7236330_10 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000612 276.0
HFD2_k127_7236330_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005224 241.0
HFD2_k127_7236330_12 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000001225 201.0
HFD2_k127_7236330_13 - - - - 0.0000000000000000000000000000000000000000000000000000005051 202.0
HFD2_k127_7236330_14 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000001401 193.0
HFD2_k127_7236330_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 581.0
HFD2_k127_7236330_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 552.0
HFD2_k127_7236330_4 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 493.0
HFD2_k127_7236330_5 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 378.0
HFD2_k127_7236330_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 367.0
HFD2_k127_7236330_7 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 331.0
HFD2_k127_7236330_8 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 308.0
HFD2_k127_7236330_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000225 279.0
HFD2_k127_7238278_0 carboxylic acid catabolic process K01684 - 4.2.1.6 5.062e-244 758.0
HFD2_k127_7238278_1 Dehydrogenase K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 477.0
HFD2_k127_7238278_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000007125 58.0
HFD2_k127_7241971_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 380.0
HFD2_k127_7241971_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000005568 149.0
HFD2_k127_7241971_2 transcription regulator containing HTH domain - - - 0.000000000000000000000000000000000000009608 148.0
HFD2_k127_7241971_3 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000008944 120.0
HFD2_k127_7261414_0 Dehydrogenase E1 component K11381 - 1.2.4.4 8.4e-323 1001.0
HFD2_k127_7261414_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.414e-198 625.0
HFD2_k127_7261414_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 512.0
HFD2_k127_7261414_3 - K21449 - - 0.000000000000000000000000000000000000000000000000000001111 199.0
HFD2_k127_7261414_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000001259 124.0
HFD2_k127_7308489_0 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 566.0
HFD2_k127_7308489_1 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 551.0
HFD2_k127_7308489_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 550.0
HFD2_k127_7308489_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000004676 135.0
HFD2_k127_7327488_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 421.0
HFD2_k127_7327488_1 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 397.0
HFD2_k127_7327488_2 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 284.0
HFD2_k127_7327488_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
HFD2_k127_7327488_4 - - - - 0.00000000000000000000000000000000000000002004 160.0
HFD2_k127_7347095_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 6.157e-205 640.0
HFD2_k127_7347095_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 427.0
HFD2_k127_7347095_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 347.0
HFD2_k127_7347095_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 346.0
HFD2_k127_7372842_0 Ftsk_gamma K03466 - - 3.153e-304 962.0
HFD2_k127_7372842_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 6.686e-218 685.0
HFD2_k127_7372842_2 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 480.0
HFD2_k127_7372842_3 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 310.0
HFD2_k127_7372842_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000000000000001147 142.0
HFD2_k127_7372842_5 Putative esterase - - - 0.000000000000000000000001009 106.0
HFD2_k127_7372842_6 Rv0623-like transcription factor K19687 - - 0.00000000000000000000001392 102.0
HFD2_k127_7372842_7 Redoxin - - - 0.000000000000000000000113 104.0
HFD2_k127_7388731_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 1735.0
HFD2_k127_7441079_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.33e-255 797.0
HFD2_k127_7441079_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.88e-229 718.0
HFD2_k127_7441079_10 Methyltransferase domain - - - 0.0001651 44.0
HFD2_k127_7441079_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 446.0
HFD2_k127_7441079_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 314.0
HFD2_k127_7441079_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002587 231.0
HFD2_k127_7441079_5 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000002866 224.0
HFD2_k127_7441079_6 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000006391 194.0
HFD2_k127_7441079_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000006791 169.0
HFD2_k127_7441079_8 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000001407 170.0
HFD2_k127_7441079_9 ATPase activity K01990,K09697 - 3.6.3.7 0.000002465 49.0
HFD2_k127_74514_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 1.853e-219 689.0
HFD2_k127_74514_1 Arginosuccinate synthase K01940 - 6.3.4.5 4.342e-217 679.0
HFD2_k127_74514_10 Highly conserved protein containing a thioredoxin domain K06888,K20948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 304.0
HFD2_k127_74514_11 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000001699 226.0
HFD2_k127_74514_12 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002075 231.0
HFD2_k127_74514_13 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000007722 214.0
HFD2_k127_74514_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000009504 161.0
HFD2_k127_74514_15 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000000006054 155.0
HFD2_k127_74514_16 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000004924 156.0
HFD2_k127_74514_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 539.0
HFD2_k127_74514_20 DUF167 K09131 - - 0.000000000000002391 78.0
HFD2_k127_74514_22 - - - - 0.0002377 46.0
HFD2_k127_74514_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 513.0
HFD2_k127_74514_4 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 490.0
HFD2_k127_74514_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 398.0
HFD2_k127_74514_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 387.0
HFD2_k127_74514_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 362.0
HFD2_k127_74514_8 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 349.0
HFD2_k127_74514_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 325.0
HFD2_k127_7461741_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 286.0
HFD2_k127_7461741_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 290.0
HFD2_k127_7461741_2 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
HFD2_k127_7461741_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000001189 67.0
HFD2_k127_7461741_4 - - - - 0.00002136 52.0
HFD2_k127_7525561_0 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 0.0 1081.0
HFD2_k127_7525561_1 Dehydrogenase K00117 - 1.1.5.2 1.903e-266 834.0
HFD2_k127_7525561_10 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 291.0
HFD2_k127_7525561_11 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000003756 256.0
HFD2_k127_7525561_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000025 119.0
HFD2_k127_7525561_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 1.403e-244 758.0
HFD2_k127_7525561_3 ABC transporter - - - 3.768e-203 640.0
HFD2_k127_7525561_4 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 367.0
HFD2_k127_7525561_5 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 363.0
HFD2_k127_7525561_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 343.0
HFD2_k127_7525561_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
HFD2_k127_7525561_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
HFD2_k127_7525561_9 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 304.0
HFD2_k127_7558256_0 RAMP superfamily K19140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 405.0
HFD2_k127_7558256_1 CRISPR-associated RAMP protein, Csm4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
HFD2_k127_7558256_2 RAMP superfamily K09002 - - 0.000000000000000000000000000000000000000000000000000000000000000002479 229.0
HFD2_k127_7558256_3 AAA domain - - - 0.000000000000006419 74.0
HFD2_k127_7638384_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000003016 183.0
HFD2_k127_7638384_1 - - - - 0.0000000000000000000000000009101 121.0
HFD2_k127_7638384_2 YCII-related domain - - - 0.0000000000000000000000001101 111.0
HFD2_k127_7665448_0 Insertion element 4 transposase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 385.0
HFD2_k127_7665448_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000187 137.0
HFD2_k127_7665448_2 KTSC domain - - - 0.00000000000002145 76.0
HFD2_k127_7665448_3 - - - - 0.0004135 46.0
HFD2_k127_7696754_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 387.0
HFD2_k127_7696754_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002149 267.0
HFD2_k127_7696754_2 multi-organism process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006469 258.0
HFD2_k127_7696754_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 260.0
HFD2_k127_7696754_4 Glycosyl transferase family 1 K03429,K03715 - 2.4.1.315,2.4.1.46 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
HFD2_k127_7696754_5 histidine kinase A domain protein - - - 0.00000000000008173 79.0
HFD2_k127_7704871_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000006588 184.0
HFD2_k127_7704871_2 iron dependent repressor - - - 0.00000000000000000000000000000000000000001473 172.0
HFD2_k127_7721192_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.931e-213 670.0
HFD2_k127_7721192_1 proline dipeptidase activity - - - 3.774e-212 666.0
HFD2_k127_7721192_11 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000002065 235.0
HFD2_k127_7721192_12 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000001494 201.0
HFD2_k127_7721192_13 cytidine deaminase activity K01489 GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.5.4.5 0.000000000000000000000000000000000000000000000000000001159 205.0
HFD2_k127_7721192_14 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000002777 172.0
HFD2_k127_7721192_2 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 2.774e-195 623.0
HFD2_k127_7721192_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 510.0
HFD2_k127_7721192_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 384.0
HFD2_k127_7721192_5 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 393.0
HFD2_k127_7721192_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 382.0
HFD2_k127_7721192_7 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 317.0
HFD2_k127_7721192_8 Transketolase, thiamine diphosphate binding domain K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 302.0
HFD2_k127_7721192_9 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
HFD2_k127_7726179_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000003858 185.0
HFD2_k127_7726179_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000005773 124.0
HFD2_k127_7736658_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.228e-233 736.0
HFD2_k127_7736658_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 442.0
HFD2_k127_7736658_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 420.0
HFD2_k127_7736658_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 410.0
HFD2_k127_7736658_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 387.0
HFD2_k127_7736658_5 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 381.0
HFD2_k127_7736658_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 348.0
HFD2_k127_7736658_7 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000002672 218.0
HFD2_k127_7736658_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000004746 150.0
HFD2_k127_7745761_0 ABC transporter K15738 - - 5.436e-228 714.0
HFD2_k127_7745761_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 6.461e-204 637.0
HFD2_k127_7745761_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 592.0
HFD2_k127_7745761_3 amine dehydrogenase activity K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 605.0
HFD2_k127_7745761_4 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 543.0
HFD2_k127_7745761_5 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 374.0
HFD2_k127_7745761_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 309.0
HFD2_k127_7745761_7 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000003427 129.0
HFD2_k127_7768562_0 PFAM AMP-dependent synthetase and ligase K00666 - - 9.146e-198 630.0
HFD2_k127_7768562_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000393 286.0
HFD2_k127_7768562_2 - - - - 0.00000000001109 72.0
HFD2_k127_7776689_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 417.0
HFD2_k127_7776689_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000007627 203.0
HFD2_k127_7776689_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000001197 197.0
HFD2_k127_7776689_3 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000009076 132.0
HFD2_k127_7789132_0 efflux transmembrane transporter activity - - - 2.793e-272 855.0
HFD2_k127_7789132_1 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 336.0
HFD2_k127_7789132_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000009507 173.0
HFD2_k127_7789132_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000002256 140.0
HFD2_k127_7789132_4 DinB family - - - 0.0000000000408 63.0
HFD2_k127_7813821_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001248 215.0
HFD2_k127_7813821_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000003325 123.0
HFD2_k127_7836193_0 TonB-dependent receptor - - - 0.0 1481.0
HFD2_k127_7836193_1 DNA topological change K03168 - 5.99.1.2 1.244e-237 758.0
HFD2_k127_7836193_10 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
HFD2_k127_7836193_11 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000007347 256.0
HFD2_k127_7836193_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002154 207.0
HFD2_k127_7836193_13 - - - - 0.000000000000000000000026 109.0
HFD2_k127_7836193_2 Alpha amylase, catalytic domain K00690,K05343 - 2.4.1.7,3.2.1.1,5.4.99.16 5.586e-218 691.0
HFD2_k127_7836193_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 534.0
HFD2_k127_7836193_4 Periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 513.0
HFD2_k127_7836193_5 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 482.0
HFD2_k127_7836193_6 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 473.0
HFD2_k127_7836193_7 ankyrin repeat K15503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 463.0
HFD2_k127_7836193_8 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 435.0
HFD2_k127_7836193_9 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 363.0
HFD2_k127_7847562_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 5.511e-262 826.0
HFD2_k127_7847562_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.771e-237 749.0
HFD2_k127_7847562_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HFD2_k127_7847562_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007189 250.0
HFD2_k127_7847562_12 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000001746 197.0
HFD2_k127_7847562_13 DinB family - - - 0.00000000000000000000000000000000000000000002763 166.0
HFD2_k127_7847562_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000008493 177.0
HFD2_k127_7847562_15 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000005993 166.0
HFD2_k127_7847562_16 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.0000000000000000000000000000000000005187 148.0
HFD2_k127_7847562_17 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000000003538 128.0
HFD2_k127_7847562_18 Sporulation related domain - - - 0.00000000000000000000000002088 115.0
HFD2_k127_7847562_19 Tetratricopeptide repeat - - - 0.00000000000000000000001631 110.0
HFD2_k127_7847562_2 AMP-binding enzyme C-terminal domain K00666 - - 1.543e-199 635.0
HFD2_k127_7847562_20 Haem-binding domain - - - 0.00000000000000000000003905 106.0
HFD2_k127_7847562_22 - - - - 0.0000001458 64.0
HFD2_k127_7847562_3 response to abiotic stimulus K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 464.0
HFD2_k127_7847562_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 430.0
HFD2_k127_7847562_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
HFD2_k127_7847562_6 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 370.0
HFD2_k127_7847562_7 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 361.0
HFD2_k127_7847562_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 308.0
HFD2_k127_7847562_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 307.0
HFD2_k127_7853276_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 417.0
HFD2_k127_7853276_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
HFD2_k127_7854239_0 Belongs to the GSP D family K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 539.0
HFD2_k127_7854239_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000005292 222.0
HFD2_k127_7854239_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005303 230.0
HFD2_k127_7854239_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000006265 206.0
HFD2_k127_7855209_0 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 582.0
HFD2_k127_7855209_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 565.0
HFD2_k127_7855209_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 425.0
HFD2_k127_7855209_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001834 274.0
HFD2_k127_7855209_5 Domain of unknown function (DUF4384) - - - 0.00000000000000000000000000000000000000000000884 173.0
HFD2_k127_7855209_6 Caspase domain - - - 0.000000000000000000000000000000003233 132.0
HFD2_k127_7869526_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1009.0
HFD2_k127_7869526_1 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 2.476e-228 717.0
HFD2_k127_7869526_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 516.0
HFD2_k127_7869526_3 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 468.0
HFD2_k127_7869526_4 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 382.0
HFD2_k127_7869526_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 316.0
HFD2_k127_7869526_6 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000002008 163.0
HFD2_k127_7869526_7 Sodium/calcium exchanger protein K07300 - - 0.00001551 48.0
HFD2_k127_7869526_8 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00001565 57.0
HFD2_k127_7880869_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.006e-245 764.0
HFD2_k127_7880869_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 381.0
HFD2_k127_7880869_2 N-terminal domain of toast_rack, DUF2154 - - - 0.000000000000000000000000000000000000000000000000000285 198.0
HFD2_k127_7880869_3 - - - - 0.00000000000000001398 86.0
HFD2_k127_7892598_0 Heat shock 70 kDa protein K04043 - - 0.0 1040.0
HFD2_k127_7892598_1 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 552.0
HFD2_k127_7892598_10 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 337.0
HFD2_k127_7892598_11 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
HFD2_k127_7892598_12 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 324.0
HFD2_k127_7892598_13 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 300.0
HFD2_k127_7892598_14 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
HFD2_k127_7892598_15 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000002536 190.0
HFD2_k127_7892598_16 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000005974 175.0
HFD2_k127_7892598_17 PFAM regulatory protein, MerR K13640 - - 0.000000000000000000000000000000000000000000001916 168.0
HFD2_k127_7892598_18 - - - - 0.000000000000000000000000000000000000000000002125 174.0
HFD2_k127_7892598_19 methyltransferase - - - 0.000000000000000000000000000000000000000004141 166.0
HFD2_k127_7892598_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 486.0
HFD2_k127_7892598_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 437.0
HFD2_k127_7892598_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 431.0
HFD2_k127_7892598_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 422.0
HFD2_k127_7892598_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 420.0
HFD2_k127_7892598_7 PP-loop family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 407.0
HFD2_k127_7892598_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 417.0
HFD2_k127_7892598_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 344.0
HFD2_k127_7904529_0 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 4.031e-247 794.0
HFD2_k127_7904529_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000004009 217.0
HFD2_k127_7904529_2 peptidase inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000001574 195.0
HFD2_k127_7909834_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1052.0
HFD2_k127_7909834_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.467e-202 637.0
HFD2_k127_7909834_10 - - - - 0.000000000000000000000001059 106.0
HFD2_k127_7909834_11 - - - - 0.0000000000000000013 91.0
HFD2_k127_7909834_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 468.0
HFD2_k127_7909834_3 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 357.0
HFD2_k127_7909834_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 298.0
HFD2_k127_7909834_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HFD2_k127_7909834_6 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000001777 183.0
HFD2_k127_7909834_7 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000001173 181.0
HFD2_k127_7909834_8 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000001405 174.0
HFD2_k127_7909834_9 TIGRFAM TonB K03832 - - 0.00000000000000000000000000000001475 130.0
HFD2_k127_7910459_0 PFAM membrane bound O-acyl transferase MBOAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 428.0
HFD2_k127_7910459_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 352.0
HFD2_k127_7910459_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002127 268.0
HFD2_k127_7921098_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 1.012e-215 676.0
HFD2_k127_7921098_1 PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 475.0
HFD2_k127_7921098_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 435.0
HFD2_k127_7921098_3 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 354.0
HFD2_k127_7921098_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
HFD2_k127_7921098_5 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 295.0
HFD2_k127_7921098_6 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000004404 50.0
HFD2_k127_7943029_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 467.0
HFD2_k127_7943029_1 - - - - 0.00000000000000000000000000000000000004174 154.0
HFD2_k127_7943029_2 - - - - 0.0000000000000000000000007289 117.0
HFD2_k127_7943029_3 - - - - 0.000000000000000000002109 96.0
HFD2_k127_7957958_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1182.0
HFD2_k127_7957958_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 8.208e-200 625.0
HFD2_k127_7957958_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 499.0
HFD2_k127_7957958_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 330.0
HFD2_k127_7957958_4 Redoxin - - - 0.0000000000000000000000000000000000006217 148.0
HFD2_k127_7957958_5 PIN domain - - - 0.00000000000000000000000000000000001304 139.0
HFD2_k127_7957958_6 Redoxin - - - 0.000000000000000000000000001981 119.0
HFD2_k127_7957958_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000001718 95.0
HFD2_k127_7981949_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 512.0
HFD2_k127_7981949_1 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 465.0
HFD2_k127_7981949_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 408.0
HFD2_k127_7981949_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 317.0
HFD2_k127_7981949_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000002034 190.0
HFD2_k127_7981949_6 PFAM Xylose isomerase - - - 0.0000000004044 68.0
HFD2_k127_7981949_7 - - - - 0.000007798 59.0
HFD2_k127_7982309_1 protein conserved in bacteria - - - 0.00000000000000000000001952 107.0
HFD2_k127_7982397_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 7.795e-223 694.0
HFD2_k127_7982397_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
HFD2_k127_7982397_2 - K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001955 284.0
HFD2_k127_7982397_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 282.0
HFD2_k127_7982397_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000009947 190.0
HFD2_k127_7989183_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 8.752e-304 938.0
HFD2_k127_7989183_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 535.0
HFD2_k127_7989183_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 514.0
HFD2_k127_7989183_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 411.0
HFD2_k127_7989183_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 303.0
HFD2_k127_7989183_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005864 260.0
HFD2_k127_7989183_6 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000004703 237.0
HFD2_k127_7989183_8 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000783 93.0
HFD2_k127_7989183_9 PFAM YbbR family protein - - - 0.0000001775 60.0
HFD2_k127_7991477_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1161.0
HFD2_k127_7991477_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.601e-280 881.0
HFD2_k127_7991477_10 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 357.0
HFD2_k127_7991477_11 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 330.0
HFD2_k127_7991477_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 316.0
HFD2_k127_7991477_13 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007259 299.0
HFD2_k127_7991477_14 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009854 274.0
HFD2_k127_7991477_15 curli production assembly transport component CsgG K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003488 284.0
HFD2_k127_7991477_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001635 274.0
HFD2_k127_7991477_17 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
HFD2_k127_7991477_18 curli production assembly transport component CsgG K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
HFD2_k127_7991477_19 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001007 230.0
HFD2_k127_7991477_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 1.41e-225 717.0
HFD2_k127_7991477_20 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000006709 214.0
HFD2_k127_7991477_21 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000001071 207.0
HFD2_k127_7991477_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000002661 199.0
HFD2_k127_7991477_23 DUF218 domain - - - 0.0000000000000000000000000000000000000000001672 166.0
HFD2_k127_7991477_24 - - - - 0.000000000000000000000000000000000000000259 159.0
HFD2_k127_7991477_25 - - - - 0.0000000000000000000000000000000000001639 153.0
HFD2_k127_7991477_26 - - - - 0.0000000000000000000000000000000000418 145.0
HFD2_k127_7991477_27 - - - - 0.0000000000000000000000000000001286 128.0
HFD2_k127_7991477_28 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000001247 130.0
HFD2_k127_7991477_29 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000009099 104.0
HFD2_k127_7991477_3 Cytochrome c - - - 1.972e-202 638.0
HFD2_k127_7991477_30 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000009646 90.0
HFD2_k127_7991477_31 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000003328 103.0
HFD2_k127_7991477_32 mRNA binding K07339 - - 0.00000000000000003935 82.0
HFD2_k127_7991477_33 cAMP biosynthetic process K03641 - - 0.00000000000005846 86.0
HFD2_k127_7991477_34 cAMP biosynthetic process K03641,K08282,K12132 - 2.7.11.1 0.000004086 60.0
HFD2_k127_7991477_4 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 7.466e-194 614.0
HFD2_k127_7991477_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 593.0
HFD2_k127_7991477_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 522.0
HFD2_k127_7991477_7 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 509.0
HFD2_k127_7991477_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
HFD2_k127_7991477_9 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
HFD2_k127_7999509_0 Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 462.0
HFD2_k127_7999509_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000215 79.0
HFD2_k127_8008142_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1285.0
HFD2_k127_8008142_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 479.0
HFD2_k127_8008142_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 432.0
HFD2_k127_8008142_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 402.0
HFD2_k127_8008142_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 357.0
HFD2_k127_8008142_5 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 337.0
HFD2_k127_8008142_6 ThiJ PfpI K18199 - 4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 282.0
HFD2_k127_8008142_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000007499 151.0
HFD2_k127_8008142_8 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.00000004283 64.0
HFD2_k127_8057318_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1368.0
HFD2_k127_8057318_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 352.0
HFD2_k127_8057318_2 WD40-like Beta Propeller Repeat K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 314.0
HFD2_k127_8057318_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 294.0
HFD2_k127_8057318_4 TonB-dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001314 288.0
HFD2_k127_8057318_5 FES K03575 - - 0.000000000000000000000000000000000000000000000000009813 183.0
HFD2_k127_8057318_6 - - - - 0.000000000000000000000000000000000000003105 154.0
HFD2_k127_808121_0 Dehydrogenase K00117 - 1.1.5.2 2.527e-263 827.0
HFD2_k127_808121_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 467.0
HFD2_k127_808121_3 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 401.0
HFD2_k127_8088775_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000001374 207.0
HFD2_k127_8088775_1 DoxX - - - 0.00000000000000000000000000000000007861 137.0
HFD2_k127_8088775_2 electron transfer activity - - - 0.000000000000004534 79.0
HFD2_k127_8106832_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.0 1059.0
HFD2_k127_8106832_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.361e-242 767.0
HFD2_k127_8106832_10 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 311.0
HFD2_k127_8106832_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
HFD2_k127_8106832_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000007161 254.0
HFD2_k127_8106832_13 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000005233 243.0
HFD2_k127_8106832_14 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
HFD2_k127_8106832_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001274 221.0
HFD2_k127_8106832_16 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000199 159.0
HFD2_k127_8106832_17 - - - - 0.000000000000000000000000000000000000001205 150.0
HFD2_k127_8106832_18 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000003752 144.0
HFD2_k127_8106832_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000008589 132.0
HFD2_k127_8106832_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 481.0
HFD2_k127_8106832_20 Protein of unknown function (DUF2809) - - - 0.00000000000000001408 90.0
HFD2_k127_8106832_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 484.0
HFD2_k127_8106832_4 ERAP1-like C-terminal domain K01263 - 3.4.11.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 422.0
HFD2_k127_8106832_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 407.0
HFD2_k127_8106832_6 PFAM NHL repeat containing protein K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 409.0
HFD2_k127_8106832_7 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 387.0
HFD2_k127_8106832_8 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 332.0
HFD2_k127_8106832_9 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
HFD2_k127_8139622_0 efflux transmembrane transporter activity - - - 2.43e-300 941.0
HFD2_k127_8139622_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000006385 96.0
HFD2_k127_8139622_2 MacB-like periplasmic core domain - - - 0.0000004232 51.0
HFD2_k127_8149289_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 377.0
HFD2_k127_8149289_1 protocatechuate 3,4-dioxygenase, beta subunit K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
HFD2_k127_8149289_2 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000004351 181.0
HFD2_k127_8149289_3 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000008779 156.0
HFD2_k127_8149289_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000008357 147.0
HFD2_k127_8223310_0 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 523.0
HFD2_k127_8223310_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 373.0
HFD2_k127_8223310_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000008438 201.0
HFD2_k127_8223310_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000007332 158.0
HFD2_k127_8230293_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1712.0
HFD2_k127_8230293_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 1.201e-225 709.0
HFD2_k127_8230293_2 aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 556.0
HFD2_k127_8230293_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
HFD2_k127_8230293_4 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000004568 210.0
HFD2_k127_8230293_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000004163 179.0
HFD2_k127_8230293_6 His Kinase A (phosphoacceptor) domain - - - 0.000005505 56.0
HFD2_k127_8235014_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 453.0
HFD2_k127_8235014_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 353.0
HFD2_k127_8235014_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 308.0
HFD2_k127_8235014_3 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000004234 226.0
HFD2_k127_8255493_0 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004657 244.0
HFD2_k127_8255493_1 Methyltransferase domain - - - 0.0000000000000000001425 97.0
HFD2_k127_8255493_2 Asparagine synthase K01953 - 6.3.5.4 0.000000000001169 75.0
HFD2_k127_8255493_3 Acetyltransferase (GNAT) domain - - - 0.00000002043 58.0
HFD2_k127_8256142_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000279 242.0
HFD2_k127_8256142_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001361 242.0
HFD2_k127_8256142_2 - - - - 0.000000000000000000000000000000000000302 145.0
HFD2_k127_8256142_3 - - - - 0.0000000000000000000000001692 109.0
HFD2_k127_8317806_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.782e-292 915.0
HFD2_k127_8317806_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 544.0
HFD2_k127_8317806_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004789 259.0
HFD2_k127_8317806_3 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000001069 133.0
HFD2_k127_8317806_4 - - - - 0.000000000000000003701 92.0
HFD2_k127_8317806_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000005781 74.0
HFD2_k127_8317806_6 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000003286 52.0
HFD2_k127_8333408_0 iron dependent repressor - - - 1.153e-199 636.0
HFD2_k127_8333408_1 - - - - 0.000000000000002283 78.0
HFD2_k127_8338726_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.042e-209 666.0
HFD2_k127_8338726_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001191 174.0
HFD2_k127_8338726_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000009624 105.0
HFD2_k127_8359647_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1114.0
HFD2_k127_8359647_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 488.0
HFD2_k127_8359647_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
HFD2_k127_8418987_0 Putative glutamine amidotransferase - - - 2.375e-267 843.0
HFD2_k127_8418987_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 355.0
HFD2_k127_8418987_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000007915 126.0
HFD2_k127_8418987_11 PA domain - - - 0.00000000000001221 76.0
HFD2_k127_8418987_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 367.0
HFD2_k127_8418987_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
HFD2_k127_8418987_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 304.0
HFD2_k127_8418987_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 297.0
HFD2_k127_8418987_6 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 290.0
HFD2_k127_8418987_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 290.0
HFD2_k127_8418987_8 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001286 271.0
HFD2_k127_8418987_9 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004567 269.0
HFD2_k127_8423169_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 333.0
HFD2_k127_8423169_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 296.0
HFD2_k127_8423169_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
HFD2_k127_8423169_3 - - - - 0.00000000000000000000000000000000000000000000000000000007471 214.0
HFD2_k127_8445715_0 PQQ-like domain - - - 1.396e-291 902.0
HFD2_k127_8445715_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
HFD2_k127_8453528_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 444.0
HFD2_k127_8453528_1 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 406.0
HFD2_k127_8480662_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 513.0
HFD2_k127_8480662_1 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 459.0
HFD2_k127_8480662_10 cell adhesion involved in biofilm formation - - - 0.000000003847 60.0
HFD2_k127_8480662_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 411.0
HFD2_k127_8480662_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 305.0
HFD2_k127_8480662_4 - - - - 0.00000000000000000000000000000000000000000000000005268 187.0
HFD2_k127_8480662_5 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000002377 176.0
HFD2_k127_8480662_6 NHL repeat - - - 0.00000000000000000000000000000000000000008421 160.0
HFD2_k127_8480662_7 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000001075 160.0
HFD2_k127_8480662_8 - - - - 0.00000000000000000000000000000002038 127.0
HFD2_k127_8480662_9 Glycosyl transferase family 2 - - - 0.00000000000000000791 93.0
HFD2_k127_8487466_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 596.0
HFD2_k127_8487466_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 562.0
HFD2_k127_8487466_11 lactoylglutathione lyase activity K03088 - - 0.0003641 43.0
HFD2_k127_8487466_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 390.0
HFD2_k127_8487466_3 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000345 279.0
HFD2_k127_8487466_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000001451 153.0
HFD2_k127_8487466_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000006517 127.0
HFD2_k127_8487466_6 Poly-gamma-glutamate hydrolase - - - 0.0000000000000000000001637 105.0
HFD2_k127_8487466_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000006564 100.0
HFD2_k127_8487466_9 Helix-turn-helix domain K15539 - - 0.000000000000002323 89.0
HFD2_k127_8549032_0 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 340.0
HFD2_k127_8549032_1 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000003179 214.0
HFD2_k127_8549032_2 - - - - 0.00000000000000000000000007349 117.0
HFD2_k127_8549032_4 DinB family - - - 0.0000000000000000008024 93.0
HFD2_k127_8549032_5 Dehydrogenase K00114 - 1.1.2.8 0.0000000789 55.0
HFD2_k127_8572204_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
HFD2_k127_8572204_1 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 311.0
HFD2_k127_8572204_2 Planctomycete cytochrome C - - - 0.000000000000000004994 91.0
HFD2_k127_8578266_0 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 616.0
HFD2_k127_8578266_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
HFD2_k127_8578266_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008764 250.0
HFD2_k127_8580087_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 512.0
HFD2_k127_8580087_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 490.0
HFD2_k127_8580087_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000001805 219.0
HFD2_k127_8580087_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000006237 172.0
HFD2_k127_8580087_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000002229 160.0
HFD2_k127_8580087_5 - - - - 0.0000000000000000000000000000001078 135.0
HFD2_k127_8580087_6 PFAM Cold-shock K03704 - - 0.000000000000000000000000000001369 123.0
HFD2_k127_8580087_7 antitoxin K07172 - - 0.0000000000000000000000000002812 116.0
HFD2_k127_8580087_8 Pyrrolo-quinoline quinone K00114,K17760 - 1.1.2.8,1.1.9.1 0.0000000000000000000000008018 111.0
HFD2_k127_8580087_9 - - - - 0.00000001256 67.0
HFD2_k127_8626576_0 UDP binding domain K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 572.0
HFD2_k127_8626576_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 454.0
HFD2_k127_8626576_10 bacterial-type flagellum assembly K02420,K03227 - - 0.000000000007168 70.0
HFD2_k127_8626576_11 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000009923 59.0
HFD2_k127_8626576_13 Flagellar biosynthesis protein, FliO K02418 - - 0.00001003 51.0
HFD2_k127_8626576_2 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
HFD2_k127_8626576_3 FlhB HrpN YscU SpaS Family K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 330.0
HFD2_k127_8626576_4 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 325.0
HFD2_k127_8626576_5 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 319.0
HFD2_k127_8626576_6 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
HFD2_k127_8626576_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003832 212.0
HFD2_k127_8626576_8 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000005066 142.0
HFD2_k127_8626576_9 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000007939 81.0
HFD2_k127_8677211_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.1e-272 847.0
HFD2_k127_8677211_1 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
HFD2_k127_8677211_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000004307 98.0
HFD2_k127_8677211_3 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000009024 91.0
HFD2_k127_8677211_4 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.000000000000006163 78.0
HFD2_k127_8677211_5 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000001249 57.0
HFD2_k127_8691020_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 578.0
HFD2_k127_8691020_1 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 549.0
HFD2_k127_8691020_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 338.0
HFD2_k127_8691020_3 Periplasmic binding protein-like domain - - - 0.000000000000000000002029 102.0
HFD2_k127_8693232_0 PFAM LmbE family protein - - - 1.893e-275 872.0
HFD2_k127_8693232_1 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 479.0
HFD2_k127_8693232_2 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 0.000000000000000000000000000000000000000000000000000000000000000008731 229.0
HFD2_k127_8693232_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000006513 113.0
HFD2_k127_8693232_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000008746 96.0
HFD2_k127_8693232_5 Sodium:solute symporter family - - - 0.00000000000005642 75.0
HFD2_k127_8693232_6 - - - - 0.00000000002049 74.0
HFD2_k127_8717542_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.484e-227 709.0
HFD2_k127_8717542_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 514.0
HFD2_k127_8717542_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 350.0
HFD2_k127_8717542_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
HFD2_k127_8717542_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
HFD2_k127_8725858_0 Rhodanese-like domain K01069 - 3.1.2.6 3.345e-225 711.0
HFD2_k127_8725858_1 DegT/DnrJ/EryC1/StrS aminotransferase family K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 441.0
HFD2_k127_8725858_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 446.0
HFD2_k127_8725858_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000006381 157.0
HFD2_k127_8725858_4 PFAM Cold-shock K03704 - - 0.00000000000000000000000000000002301 126.0
HFD2_k127_8745190_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 394.0
HFD2_k127_8745190_1 - - - - 0.00000000000000000007853 93.0
HFD2_k127_884647_0 PFAM peptidase M13 K01415 - 3.4.24.71 2.678e-249 785.0
HFD2_k127_884647_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.129e-198 633.0
HFD2_k127_884647_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000046 256.0
HFD2_k127_884647_11 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000002385 203.0
HFD2_k127_884647_12 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000009394 202.0
HFD2_k127_884647_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000003415 194.0
HFD2_k127_884647_14 BON domain - - - 0.0000000000000000000000000000000000000000000000001505 186.0
HFD2_k127_884647_15 - - - - 0.00000000000000000000000000000000000000000000003719 184.0
HFD2_k127_884647_16 Trm112p-like protein K09791 - - 0.00000000000000000000000002543 109.0
HFD2_k127_884647_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 562.0
HFD2_k127_884647_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 551.0
HFD2_k127_884647_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 525.0
HFD2_k127_884647_5 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 456.0
HFD2_k127_884647_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
HFD2_k127_884647_7 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 306.0
HFD2_k127_884647_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 292.0
HFD2_k127_884647_9 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
HFD2_k127_885906_0 Ribosomal protein S1 K02945 - - 9.302e-268 835.0
HFD2_k127_885906_1 Peptidase M56 - - - 4.899e-209 664.0
HFD2_k127_885906_10 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000002829 135.0
HFD2_k127_885906_11 - - - - 0.000000000000000000001964 99.0
HFD2_k127_885906_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 478.0
HFD2_k127_885906_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 439.0
HFD2_k127_885906_4 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 384.0
HFD2_k127_885906_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 388.0
HFD2_k127_885906_6 GMC oxidoreductase K06151 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000001832 235.0
HFD2_k127_885906_7 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000002759 213.0
HFD2_k127_885906_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000001774 191.0
HFD2_k127_885906_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000001044 166.0
HFD2_k127_915329_0 Belongs to the UbiD family K03182 - 4.1.1.98 5.47e-251 780.0
HFD2_k127_915329_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
HFD2_k127_915329_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 305.0
HFD2_k127_915329_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003083 263.0
HFD2_k127_915329_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
HFD2_k127_915329_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000418 230.0
HFD2_k127_930036_0 Beta-propeller repeat - - - 6.315e-215 711.0
HFD2_k127_930036_1 MoeZ MoeB domain K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000001678 264.0
HFD2_k127_937761_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 7.252e-283 879.0
HFD2_k127_937761_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.366e-254 798.0
HFD2_k127_937761_10 Belongs to the ATPase B chain family K02109 - - 0.0000000000000000000000000009764 117.0
HFD2_k127_937761_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000006683 96.0
HFD2_k127_937761_12 Ribbon-helix-helix protein, copG family - - - 0.00000003618 58.0
HFD2_k127_937761_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000005543 51.0
HFD2_k127_937761_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 461.0
HFD2_k127_937761_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 385.0
HFD2_k127_937761_4 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001159 265.0
HFD2_k127_937761_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005285 254.0
HFD2_k127_937761_6 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
HFD2_k127_937761_7 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000000000000000000002254 220.0
HFD2_k127_937761_8 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms - - - 0.0000000000000000000000000000000000000000000001687 173.0
HFD2_k127_937761_9 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000006253 129.0
HFD2_k127_952387_0 Glycogen debranching enzyme N terminal - - - 8.946e-286 896.0
HFD2_k127_952387_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 7.107e-271 848.0
HFD2_k127_952387_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001087 258.0
HFD2_k127_952387_3 Protein of unknown function (DUF3309) - - - 0.000000000000000008376 83.0
HFD2_k127_952387_4 - - - - 0.0000000000005788 69.0
HFD2_k127_952387_5 - - - - 0.000000004402 59.0
HFD2_k127_964619_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1166.0
HFD2_k127_964619_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 386.0
HFD2_k127_964619_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 273.0
HFD2_k127_964619_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007271 243.0
HFD2_k127_964619_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000003753 243.0
HFD2_k127_964619_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000002551 225.0
HFD2_k127_964619_7 AntiSigma factor - - - 0.0000000001969 69.0
HFD2_k127_968292_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 562.0
HFD2_k127_968292_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
HFD2_k127_968292_2 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
HFD2_k127_968292_3 GAF domain K01768,K02584,K07183,K22010 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 346.0
HFD2_k127_968292_4 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 322.0
HFD2_k127_968292_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000004865 216.0
HFD2_k127_968292_6 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000000000016 168.0
HFD2_k127_968292_7 Methyltransferase domain - - - 0.000000000000000000000001536 109.0
HFD2_k127_97443_0 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 549.0
HFD2_k127_97443_1 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 464.0
HFD2_k127_97443_10 - - - - 0.0000000000000000000002983 102.0
HFD2_k127_97443_11 - - - - 0.00000000000001494 75.0
HFD2_k127_97443_12 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000002198 74.0
HFD2_k127_97443_2 Major Facilitator Superfamily K07552,K18552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 329.0
HFD2_k127_97443_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
HFD2_k127_97443_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
HFD2_k127_97443_6 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009439,GO:0009440,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000002379 226.0
HFD2_k127_97443_7 - - - - 0.00000000000000000000000000000000000000001484 164.0
HFD2_k127_97443_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000003119 155.0
HFD2_k127_97443_9 cell septum assembly K02487,K06596,K08372 - - 0.00000000000000000000003422 102.0