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Overview

ID MAG01641
Name HFD2_bin.3
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Acidiferrales
Family UBA7541
Genus JACQDE01
Species
Assembly information
Completeness (%) 74.05
Contamination (%) 1.42
GC content (%) 61.0
N50 (bp) 7,986
Genome size (bp) 3,233,607

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2814

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1006191_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 435.0
HFD2_k127_1006191_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 257.0
HFD2_k127_1006191_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000005839 204.0
HFD2_k127_1006191_3 Protein of unknown function (DUF3106) - - - 0.00003169 54.0
HFD2_k127_1006191_4 Putative zinc-finger - - - 0.0001282 51.0
HFD2_k127_1006868_0 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 299.0
HFD2_k127_1006868_1 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002007 286.0
HFD2_k127_1006868_2 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000001538 174.0
HFD2_k127_1006868_3 Biotin-requiring enzyme - - - 0.000000000000000000000003688 109.0
HFD2_k127_1006868_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000001406 93.0
HFD2_k127_1006868_5 - - - - 0.0006574 46.0
HFD2_k127_1016405_0 Tricorn protease PDZ domain K08676 - - 0.0 1313.0
HFD2_k127_1016405_1 Amidohydrolase family K06015 - 3.5.1.81 1.424e-251 786.0
HFD2_k127_1016405_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 556.0
HFD2_k127_1016405_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 389.0
HFD2_k127_1016405_4 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 384.0
HFD2_k127_1016405_5 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004962 269.0
HFD2_k127_1016405_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007891 254.0
HFD2_k127_1016405_7 - - - - 0.0002938 48.0
HFD2_k127_1030872_0 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 586.0
HFD2_k127_1030872_1 Amidohydrolase family K01466 - 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 354.0
HFD2_k127_1030872_2 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000001064 147.0
HFD2_k127_1030872_3 membrane - - - 0.00000001644 55.0
HFD2_k127_103860_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 611.0
HFD2_k127_103860_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000000000000000000000000000004816 219.0
HFD2_k127_104313_0 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000002947 179.0
HFD2_k127_104313_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000005966 168.0
HFD2_k127_104313_2 Diacylglycerol kinase K07029 - 2.7.1.107 0.000000000000000000000000000000000000002756 158.0
HFD2_k127_104313_3 NUDIX domain - - - 0.00000000000000000000000000000000009238 139.0
HFD2_k127_104313_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000004177 94.0
HFD2_k127_104313_6 - K05826 - - 0.0000001996 56.0
HFD2_k127_104313_7 Belongs to the ompA family - - - 0.00001072 49.0
HFD2_k127_1044420_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 516.0
HFD2_k127_1044420_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
HFD2_k127_1044420_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 369.0
HFD2_k127_1044420_3 ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 360.0
HFD2_k127_1044420_4 'ABC-type proline glycine betaine transport K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 325.0
HFD2_k127_1044420_5 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 321.0
HFD2_k127_1044420_6 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008055 245.0
HFD2_k127_1081500_0 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 423.0
HFD2_k127_1081500_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000665 294.0
HFD2_k127_1081500_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000867 194.0
HFD2_k127_1081500_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000001239 106.0
HFD2_k127_1081500_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0002559 46.0
HFD2_k127_1082447_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 301.0
HFD2_k127_1082447_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000001963 160.0
HFD2_k127_1082447_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000009305 154.0
HFD2_k127_1083514_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 524.0
HFD2_k127_1083514_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 404.0
HFD2_k127_1083514_2 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000001284 220.0
HFD2_k127_1083514_3 - - - - 0.0000000000000000000000000000000000000000000007115 175.0
HFD2_k127_1083514_4 - - - - 0.00000000000000000000000000000000001364 146.0
HFD2_k127_1083514_5 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000005149 130.0
HFD2_k127_1083514_6 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000009121 110.0
HFD2_k127_1083514_8 MacB-like periplasmic core domain - - - 0.00001941 55.0
HFD2_k127_1121300_0 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 321.0
HFD2_k127_1121300_1 FecR protein - - - 0.0000000000000000000000000000000000000000000001009 188.0
HFD2_k127_1121300_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000004978 135.0
HFD2_k127_1165296_0 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 329.0
HFD2_k127_1165296_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002318 262.0
HFD2_k127_1165296_10 oxidoreductase activity - - - 0.0000000000000001311 93.0
HFD2_k127_1165296_2 Pirin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
HFD2_k127_1165296_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
HFD2_k127_1165296_4 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001421 221.0
HFD2_k127_1165296_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000001047 222.0
HFD2_k127_1165296_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001563 218.0
HFD2_k127_1165296_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000008182 191.0
HFD2_k127_1165296_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000001568 152.0
HFD2_k127_1165296_9 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000003541 137.0
HFD2_k127_1169407_0 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 5.021e-298 930.0
HFD2_k127_1169407_1 amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 501.0
HFD2_k127_1169407_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 474.0
HFD2_k127_1169407_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000005684 204.0
HFD2_k127_1169612_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 449.0
HFD2_k127_1169612_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
HFD2_k127_1176629_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 601.0
HFD2_k127_1176629_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
HFD2_k127_1176629_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000166 79.0
HFD2_k127_1176629_3 Methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000343 53.0
HFD2_k127_1182593_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 8.554e-233 728.0
HFD2_k127_1182593_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 430.0
HFD2_k127_1182593_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001998 214.0
HFD2_k127_1182593_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000001064 112.0
HFD2_k127_1182593_4 Probable zinc-ribbon domain - - - 0.000000000001937 69.0
HFD2_k127_1188775_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1327.0
HFD2_k127_1188775_1 aminopeptidase activity K07004 - - 1.089e-223 715.0
HFD2_k127_1188775_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000001235 218.0
HFD2_k127_1193436_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 378.0
HFD2_k127_1193436_1 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000001306 220.0
HFD2_k127_1193436_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000009347 161.0
HFD2_k127_1206251_0 ATP-dependent peptidase activity K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 616.0
HFD2_k127_1206251_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000001304 189.0
HFD2_k127_1206251_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001032 170.0
HFD2_k127_1206251_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000256 171.0
HFD2_k127_123739_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 572.0
HFD2_k127_123739_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 372.0
HFD2_k127_123739_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000005064 62.0
HFD2_k127_123739_13 cheY-homologous receiver domain - - - 0.000002294 56.0
HFD2_k127_123739_14 CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.00009374 51.0
HFD2_k127_123739_2 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 343.0
HFD2_k127_123739_3 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001052 292.0
HFD2_k127_123739_4 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009644 269.0
HFD2_k127_123739_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
HFD2_k127_123739_6 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001303 251.0
HFD2_k127_123739_7 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000008751 231.0
HFD2_k127_123739_8 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000001718 147.0
HFD2_k127_123739_9 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000003887 116.0
HFD2_k127_1254787_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 361.0
HFD2_k127_1254787_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000003335 257.0
HFD2_k127_1267702_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.631e-212 676.0
HFD2_k127_1267784_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 359.0
HFD2_k127_1267784_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000004319 189.0
HFD2_k127_1267784_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000006102 95.0
HFD2_k127_1269161_0 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 353.0
HFD2_k127_1269161_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000002932 250.0
HFD2_k127_1269161_2 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000622 172.0
HFD2_k127_1269161_3 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000584 102.0
HFD2_k127_1269161_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000122 100.0
HFD2_k127_1269161_5 - - - - 0.0000000000001293 76.0
HFD2_k127_1280749_0 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 2.943e-285 894.0
HFD2_k127_1280749_1 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 8.968e-199 633.0
HFD2_k127_1280749_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 616.0
HFD2_k127_1280749_3 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 517.0
HFD2_k127_1280749_4 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 497.0
HFD2_k127_1280749_5 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 441.0
HFD2_k127_1280749_6 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001528 230.0
HFD2_k127_1280749_7 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000005129 162.0
HFD2_k127_1294191_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000002773 260.0
HFD2_k127_1294191_1 PASTA domain K12132 - 2.7.11.1 0.000000000001378 72.0
HFD2_k127_1304362_0 Belongs to the CarB family K01955 - 6.3.5.5 1.778e-284 894.0
HFD2_k127_1304362_1 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000009819 195.0
HFD2_k127_1316437_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 3.973e-246 767.0
HFD2_k127_1316437_1 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 430.0
HFD2_k127_1316437_10 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000001014 173.0
HFD2_k127_1316437_11 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000000000000000000000000002978 136.0
HFD2_k127_1316437_12 Transcriptional regulator, BadM Rrf2 family - - - 0.000000000000000000006193 99.0
HFD2_k127_1316437_13 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000006748 101.0
HFD2_k127_1316437_2 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 388.0
HFD2_k127_1316437_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 331.0
HFD2_k127_1316437_4 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 329.0
HFD2_k127_1316437_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 317.0
HFD2_k127_1316437_6 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 262.0
HFD2_k127_1316437_7 Coenzyme A transferase K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000009828 255.0
HFD2_k127_1316437_8 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01031 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
HFD2_k127_1316437_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
HFD2_k127_1318106_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
HFD2_k127_1318106_1 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 301.0
HFD2_k127_1318106_2 RNA recognition motif - - - 0.0000000000000000000003606 102.0
HFD2_k127_1319221_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
HFD2_k127_1319221_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000002321 179.0
HFD2_k127_1320268_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 417.0
HFD2_k127_1320268_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000001542 148.0
HFD2_k127_1320268_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000002572 85.0
HFD2_k127_1320268_3 PFAM Metalloenzyme - - - 0.000002746 49.0
HFD2_k127_1330959_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 524.0
HFD2_k127_1330959_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 471.0
HFD2_k127_1330959_2 COG2217 Cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000003196 57.0
HFD2_k127_1330959_3 domain protein - - - 0.0000004604 56.0
HFD2_k127_133724_0 cellulose binding - - - 0.0 1166.0
HFD2_k127_133724_1 Amidohydrolase family - - - 4.289e-282 899.0
HFD2_k127_133724_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 340.0
HFD2_k127_133724_3 Zincin-like metallopeptidase - - - 0.0000000000001249 81.0
HFD2_k127_1342353_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000007729 229.0
HFD2_k127_1342353_1 HPr kinase - - - 0.0000000000000000000006636 105.0
HFD2_k127_1344838_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5e-324 1011.0
HFD2_k127_1344838_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 544.0
HFD2_k127_1344838_2 IMS family HHH motif K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 404.0
HFD2_k127_1344838_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 398.0
HFD2_k127_1344838_4 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
HFD2_k127_1344838_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000003293 231.0
HFD2_k127_1344838_6 - - - - 0.0000000000000000000000000000000000000000000000648 173.0
HFD2_k127_1345075_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 365.0
HFD2_k127_1345075_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 261.0
HFD2_k127_1345075_2 - - - - 0.0000000000000000000000000000000000000001705 160.0
HFD2_k127_1345075_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000002297 59.0
HFD2_k127_1353956_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 580.0
HFD2_k127_1353956_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000468 276.0
HFD2_k127_1353956_2 DinB family - - - 0.0000000000000000000000000000000000000000000000000000001192 199.0
HFD2_k127_1353956_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000146 177.0
HFD2_k127_1371457_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 551.0
HFD2_k127_1371457_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 348.0
HFD2_k127_1371457_2 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
HFD2_k127_137719_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 519.0
HFD2_k127_137719_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
HFD2_k127_137719_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000004952 75.0
HFD2_k127_1382010_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.211e-243 784.0
HFD2_k127_1382010_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.132e-195 640.0
HFD2_k127_1382010_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 626.0
HFD2_k127_1382010_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 372.0
HFD2_k127_1384207_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 417.0
HFD2_k127_1384207_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000424 165.0
HFD2_k127_1414724_0 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000003778 207.0
HFD2_k127_1414724_1 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000002465 199.0
HFD2_k127_1424764_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 541.0
HFD2_k127_1424764_1 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
HFD2_k127_1430203_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 546.0
HFD2_k127_1430203_1 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 479.0
HFD2_k127_1430203_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 426.0
HFD2_k127_1430203_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 357.0
HFD2_k127_1430203_4 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 323.0
HFD2_k127_1430203_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000005995 227.0
HFD2_k127_1430203_6 malate dehydrogenase (menaquinone) activity K00111 - 1.1.5.3 0.00000000000000000000000000000000000001924 152.0
HFD2_k127_1430203_7 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000003684 115.0
HFD2_k127_1430203_8 pfam rdd - - - 0.0000000000000003711 91.0
HFD2_k127_1436836_0 Tetratricopeptide repeats K12132 - 2.7.11.1 3.132e-210 679.0
HFD2_k127_1436836_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 579.0
HFD2_k127_1436836_10 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000006745 139.0
HFD2_k127_1436836_11 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000001437 129.0
HFD2_k127_1436836_12 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000007364 131.0
HFD2_k127_1436836_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000252 121.0
HFD2_k127_1436836_14 Ribosomal L32p protein family K02911 - - 0.0000000000000000000007888 96.0
HFD2_k127_1436836_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 458.0
HFD2_k127_1436836_3 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 401.0
HFD2_k127_1436836_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 392.0
HFD2_k127_1436836_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 350.0
HFD2_k127_1436836_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 310.0
HFD2_k127_1436836_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 300.0
HFD2_k127_1436836_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 299.0
HFD2_k127_1436836_9 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000009382 232.0
HFD2_k127_1466152_0 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 345.0
HFD2_k127_1466152_1 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004602 273.0
HFD2_k127_1466152_2 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000004519 172.0
HFD2_k127_1473711_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 406.0
HFD2_k127_1473711_1 PepSY-associated TM region - - - 0.000000000007646 75.0
HFD2_k127_1488825_0 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 354.0
HFD2_k127_1488825_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 311.0
HFD2_k127_1488825_2 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000000000000000000000228 203.0
HFD2_k127_1488825_3 Diguanylate cyclase - - - 0.000000000000000000000003199 120.0
HFD2_k127_1488825_4 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000009358 99.0
HFD2_k127_1488825_5 cheY-homologous receiver domain K11443 - - 0.00000000000002373 82.0
HFD2_k127_1525077_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001116 257.0
HFD2_k127_1525077_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000001563 230.0
HFD2_k127_1525077_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000001311 83.0
HFD2_k127_1528633_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 554.0
HFD2_k127_1528633_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
HFD2_k127_1534315_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 507.0
HFD2_k127_1534315_1 TrkA-C domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
HFD2_k127_1534315_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
HFD2_k127_1534315_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001724 222.0
HFD2_k127_1534315_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000005575 175.0
HFD2_k127_1534315_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000022 140.0
HFD2_k127_1534315_6 YndJ-like protein - - - 0.0000000000000000000000000000000000877 143.0
HFD2_k127_1534315_7 Hfq protein - - - 0.000000000000000000000000000001365 129.0
HFD2_k127_1534315_8 Thioesterase-like superfamily K02614 - - 0.0000000000000000000000003726 109.0
HFD2_k127_1557797_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 597.0
HFD2_k127_1557797_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000004477 107.0
HFD2_k127_1557797_2 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000183 65.0
HFD2_k127_1559492_0 WD40-like Beta Propeller Repeat - - - 2.971e-266 845.0
HFD2_k127_1559492_1 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 437.0
HFD2_k127_1559492_2 Pfam:DUF385 - - - 0.000000000000000000007737 96.0
HFD2_k127_1559492_3 - - - - 0.00000007749 61.0
HFD2_k127_1560441_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 451.0
HFD2_k127_1560441_1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.00000000000000000000000000000000000000008299 155.0
HFD2_k127_1560441_2 ThiS family K03636 - - 0.00000000000000000000000000000002115 128.0
HFD2_k127_1560441_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.00000000000000000000001876 101.0
HFD2_k127_156440_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 317.0
HFD2_k127_156440_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
HFD2_k127_156440_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000003986 193.0
HFD2_k127_156440_3 Stage II sporulation protein E K07315 - 3.1.3.3 0.0001261 51.0
HFD2_k127_1573645_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000001054 192.0
HFD2_k127_1573645_1 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000003728 152.0
HFD2_k127_1573645_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000005039 108.0
HFD2_k127_1587248_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 409.0
HFD2_k127_1587248_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 376.0
HFD2_k127_1587248_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000002316 160.0
HFD2_k127_1587248_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000001071 135.0
HFD2_k127_1587248_4 PFAM MOSC domain - - - 0.00000000000000000000000000001964 125.0
HFD2_k127_1587248_5 CAAX protease self-immunity - - - 0.000000003173 66.0
HFD2_k127_1587248_6 Tetratricopeptide repeat - - - 0.00000003297 68.0
HFD2_k127_1624520_0 Prokaryotic cytochrome b561 - - - 8.871e-242 766.0
HFD2_k127_1624520_1 Prokaryotic cytochrome b561 - - - 6.913e-227 722.0
HFD2_k127_1624520_10 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 352.0
HFD2_k127_1624520_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 350.0
HFD2_k127_1624520_12 Ornithine cyclodeaminase/mu-crystallin family K21721 - 1.5.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 329.0
HFD2_k127_1624520_13 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003483 289.0
HFD2_k127_1624520_14 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009377 282.0
HFD2_k127_1624520_15 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004881 276.0
HFD2_k127_1624520_16 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001555 202.0
HFD2_k127_1624520_17 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000001083 156.0
HFD2_k127_1624520_18 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000001524 132.0
HFD2_k127_1624520_19 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000003434 125.0
HFD2_k127_1624520_2 NapC/NirT cytochrome c family, N-terminal region - - - 6.564e-198 635.0
HFD2_k127_1624520_20 Response regulator receiver domain - - - 0.00000000000000000000000001531 115.0
HFD2_k127_1624520_21 response to oxidative stress - - - 0.00000000000000000000001817 108.0
HFD2_k127_1624520_22 - - - - 0.0000000000000000000001523 100.0
HFD2_k127_1624520_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000007962 79.0
HFD2_k127_1624520_24 phosphorelay signal transduction system - - - 0.0000006137 57.0
HFD2_k127_1624520_3 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 567.0
HFD2_k127_1624520_4 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 488.0
HFD2_k127_1624520_5 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 465.0
HFD2_k127_1624520_6 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 451.0
HFD2_k127_1624520_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 442.0
HFD2_k127_1624520_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 404.0
HFD2_k127_1624520_9 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 377.0
HFD2_k127_1661218_0 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 346.0
HFD2_k127_1661218_1 WD-40 repeat - - - 0.000000000000000000006696 97.0
HFD2_k127_1693778_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 594.0
HFD2_k127_1693778_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 306.0
HFD2_k127_1693778_2 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003077 279.0
HFD2_k127_1693778_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000001556 191.0
HFD2_k127_1693778_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000003443 167.0
HFD2_k127_1693778_5 - - - - 0.0000000000000000000002736 102.0
HFD2_k127_1718253_0 Metalloenzyme superfamily K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 421.0
HFD2_k127_1718253_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 263.0
HFD2_k127_1718253_2 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000002242 142.0
HFD2_k127_172032_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 547.0
HFD2_k127_172032_1 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 366.0
HFD2_k127_172032_10 Domain of unknown function (DUF4440) - - - 0.00008696 53.0
HFD2_k127_172032_12 Domain of unknown function (DUF4440) - - - 0.0005378 48.0
HFD2_k127_172032_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 377.0
HFD2_k127_172032_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 363.0
HFD2_k127_172032_4 PFAM LmbE family protein K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 254.0
HFD2_k127_172032_5 hyperosmotic response - - - 0.0000000000000000000001318 112.0
HFD2_k127_172032_6 response to cobalt ion - - - 0.0000000000000001281 93.0
HFD2_k127_172032_7 - - - - 0.00000000001338 68.0
HFD2_k127_172032_9 von Willebrand factor, type A K07114 - - 0.000004084 56.0
HFD2_k127_1724812_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 417.0
HFD2_k127_1724812_1 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - 0.000000000000000000000000002514 117.0
HFD2_k127_1724812_2 Phosphate-selective porin O and P - - - 0.0000000000000000000007105 109.0
HFD2_k127_1737805_0 TonB dependent receptor - - - 4.912e-256 835.0
HFD2_k127_1737805_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 457.0
HFD2_k127_1737805_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 344.0
HFD2_k127_1737805_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 346.0
HFD2_k127_1737805_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000004621 128.0
HFD2_k127_1737805_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000001036 70.0
HFD2_k127_1784957_0 Histidine kinase K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 374.0
HFD2_k127_1784957_1 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
HFD2_k127_1784957_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000004041 214.0
HFD2_k127_1784957_3 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000000000000000001564 141.0
HFD2_k127_1784957_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000009831 127.0
HFD2_k127_1784957_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000002389 114.0
HFD2_k127_1784957_6 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000001837 92.0
HFD2_k127_1784957_7 - - - - 0.000000001629 67.0
HFD2_k127_1784957_8 Protein of unknown function, DUF393 - - - 0.000000003085 63.0
HFD2_k127_1784957_9 - - - - 0.0000000265 61.0
HFD2_k127_1786503_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.485e-227 715.0
HFD2_k127_1786503_1 efflux transmembrane transporter activity K02004 - - 4.602e-209 676.0
HFD2_k127_1786503_2 efflux transmembrane transporter activity K02004 - - 2.134e-195 636.0
HFD2_k127_1786503_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 440.0
HFD2_k127_1786503_4 S23 ribosomal protein - - - 0.000000000000000000000002507 110.0
HFD2_k127_1799287_0 Protein kinase domain K12132 - 2.7.11.1 7.347e-227 727.0
HFD2_k127_1799287_1 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 376.0
HFD2_k127_1799287_2 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 370.0
HFD2_k127_1799287_3 - K01992 - - 0.0000000000000000000000000000000000000000000000000000005913 213.0
HFD2_k127_1799287_4 Multicopper oxidase K08100 - 1.3.3.5 0.000000000000000000000000000000000000000000000001137 175.0
HFD2_k127_1865663_0 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 300.0
HFD2_k127_186578_0 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008227 271.0
HFD2_k127_186578_1 Peptidase family M1 domain - - - 0.000000000000008286 87.0
HFD2_k127_190961_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 520.0
HFD2_k127_190961_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 417.0
HFD2_k127_190961_2 NmrA family - - - 0.0000000000000000000000001487 109.0
HFD2_k127_190961_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000002597 102.0
HFD2_k127_1914638_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 366.0
HFD2_k127_1914638_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007642 280.0
HFD2_k127_1914638_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004396 281.0
HFD2_k127_1914638_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000002675 209.0
HFD2_k127_1914638_4 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000735 167.0
HFD2_k127_1914638_5 TonB C terminal - - - 0.0000000000000000000002095 112.0
HFD2_k127_1914638_6 - - - - 0.00000000000000000001024 94.0
HFD2_k127_1914638_7 - - - - 0.000000000000006163 78.0
HFD2_k127_1922696_0 ABC transporter K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 405.0
HFD2_k127_1922696_1 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
HFD2_k127_1935241_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 539.0
HFD2_k127_1935241_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000001576 147.0
HFD2_k127_1935241_2 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000001451 108.0
HFD2_k127_1935241_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000001122 70.0
HFD2_k127_1939304_0 Polysulphide reductase, NrfD K00185 - - 4.266e-216 678.0
HFD2_k127_1939304_1 response to abiotic stimulus K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005414 268.0
HFD2_k127_1939304_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000004655 226.0
HFD2_k127_1939304_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000003353 139.0
HFD2_k127_1943010_0 efflux transmembrane transporter activity K02004 - - 1.246e-204 664.0
HFD2_k127_1943010_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 259.0
HFD2_k127_1943010_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000005702 237.0
HFD2_k127_1955444_0 Histidine kinase K12257 - - 0.0 1762.0
HFD2_k127_1955444_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 518.0
HFD2_k127_1955444_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 323.0
HFD2_k127_1955444_3 protein histidine kinase activity K01768,K02482,K02491,K07315,K13533,K14986,K20977 - 2.7.13.3,3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000004257 216.0
HFD2_k127_1955444_4 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000009788 203.0
HFD2_k127_1955444_5 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000002126 182.0
HFD2_k127_1955444_6 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000002962 124.0
HFD2_k127_1955444_7 DegT/DnrJ/EryC1/StrS aminotransferase family K01758 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019343,GO:0019344,GO:0019346,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0050667,GO:0070279,GO:0071265,GO:0071266,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.1 0.00008456 46.0
HFD2_k127_1966414_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.65e-211 667.0
HFD2_k127_1966414_1 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000339 164.0
HFD2_k127_1966414_2 Tetratricopeptide repeat - - - 0.00000000000000306 80.0
HFD2_k127_1966414_3 Type IV pilus biogenesis stability protein PilW - - - 0.000002317 55.0
HFD2_k127_1966414_4 - - - - 0.0001533 51.0
HFD2_k127_196701_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
HFD2_k127_196701_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000004344 227.0
HFD2_k127_196701_2 PFAM AIG2 family protein - - - 0.000000000000000000000000000001288 126.0
HFD2_k127_1967425_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 500.0
HFD2_k127_1967425_1 Belongs to the ATPase B chain family K02109 - - 0.00002281 51.0
HFD2_k127_1993393_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 403.0
HFD2_k127_1993393_1 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000003184 197.0
HFD2_k127_1993393_2 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000002192 113.0
HFD2_k127_1993393_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000008041 66.0
HFD2_k127_1993393_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00003055 53.0
HFD2_k127_1998688_0 class II (D K K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 586.0
HFD2_k127_1998688_1 Gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 482.0
HFD2_k127_1998688_10 BioY family K02014,K03523 - - 0.00000000000000000000000000000000000002271 152.0
HFD2_k127_1998688_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000005365 91.0
HFD2_k127_1998688_13 Pfam:N_methyl_2 - - - 0.00000007413 63.0
HFD2_k127_1998688_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 411.0
HFD2_k127_1998688_3 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 396.0
HFD2_k127_1998688_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 384.0
HFD2_k127_1998688_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 333.0
HFD2_k127_1998688_6 PFAM Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000001875 219.0
HFD2_k127_1998688_7 - - - - 0.000000000000000000000000000000000000000000000000000000001606 214.0
HFD2_k127_1998688_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000002172 212.0
HFD2_k127_1998688_9 PIN domain - - - 0.00000000000000000000000000000000000001257 148.0
HFD2_k127_2025797_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 452.0
HFD2_k127_2025797_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 338.0
HFD2_k127_2025797_2 BON domain - - - 0.0003328 44.0
HFD2_k127_2060648_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.962e-199 627.0
HFD2_k127_2060648_1 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 463.0
HFD2_k127_2060648_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 326.0
HFD2_k127_2060648_3 PEP-CTERM motif - - - 0.0000006996 60.0
HFD2_k127_2061932_0 ABC transporter transmembrane region K11085 - - 1.09e-303 943.0
HFD2_k127_2061932_1 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 393.0
HFD2_k127_2061932_10 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000001453 95.0
HFD2_k127_2061932_11 Glutaredoxin - - - 0.0000000000002572 78.0
HFD2_k127_2061932_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 358.0
HFD2_k127_2061932_3 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006846 225.0
HFD2_k127_2061932_4 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000000007454 216.0
HFD2_k127_2061932_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000021 148.0
HFD2_k127_2061932_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000002784 141.0
HFD2_k127_2061932_7 CBS domain - - - 0.000000000000000000000000000000007247 133.0
HFD2_k127_2061932_8 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001332 126.0
HFD2_k127_2061932_9 - - - - 0.0000000000000000000006862 108.0
HFD2_k127_2065044_0 Domain of unknown function (DUF1998) K06877 - - 5.927e-299 934.0
HFD2_k127_2065044_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000003359 183.0
HFD2_k127_2093757_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.389e-238 751.0
HFD2_k127_2097179_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 330.0
HFD2_k127_2097179_1 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000000001434 195.0
HFD2_k127_2128804_0 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 455.0
HFD2_k127_2128804_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 415.0
HFD2_k127_2130053_0 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 581.0
HFD2_k127_2130053_1 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 459.0
HFD2_k127_2130053_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001745 247.0
HFD2_k127_2130053_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000006475 226.0
HFD2_k127_2130053_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000002591 190.0
HFD2_k127_2130053_5 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000004362 147.0
HFD2_k127_2130053_6 Stress responsive A/B Barrel Domain - - - 0.0000001514 57.0
HFD2_k127_2130053_7 PilZ domain - - - 0.00001119 52.0
HFD2_k127_2188279_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.434e-223 700.0
HFD2_k127_2188279_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 284.0
HFD2_k127_2188279_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005923 284.0
HFD2_k127_2188279_3 - - - - 0.0000000000000000001789 95.0
HFD2_k127_2211109_0 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
HFD2_k127_2211109_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000179 212.0
HFD2_k127_2211109_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000002853 216.0
HFD2_k127_2211109_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000002017 191.0
HFD2_k127_2211109_4 Two component transcriptional regulator, winged helix family K02483,K07666 - - 0.0000000007147 72.0
HFD2_k127_2229650_0 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 478.0
HFD2_k127_2229650_1 Chalcone and stilbene synthases, C-terminal domain K16167 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008818 277.0
HFD2_k127_2229650_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000001141 172.0
HFD2_k127_2229650_3 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.000000000000000000000000000000003054 144.0
HFD2_k127_2229650_4 FAD dependent oxidoreductase - - - 0.000000000000002859 85.0
HFD2_k127_2229650_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000001183 53.0
HFD2_k127_2262363_0 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 409.0
HFD2_k127_2262363_1 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 367.0
HFD2_k127_2262363_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
HFD2_k127_2262363_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000001973 208.0
HFD2_k127_2262363_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000003307 167.0
HFD2_k127_2262363_5 EamA-like transporter family - - - 0.00000000000000000000000000000005511 138.0
HFD2_k127_2268245_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.03e-241 754.0
HFD2_k127_2268245_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.64e-200 632.0
HFD2_k127_2268245_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
HFD2_k127_2268245_3 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 334.0
HFD2_k127_2268245_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 325.0
HFD2_k127_2268245_5 DinB family - - - 0.000000000002927 68.0
HFD2_k127_2274258_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 531.0
HFD2_k127_2274258_1 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 342.0
HFD2_k127_2274258_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000009466 233.0
HFD2_k127_2274258_3 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000004097 207.0
HFD2_k127_2274258_4 methyltransferase activity - - - 0.000000000000000000000000000000000000000001921 161.0
HFD2_k127_2274258_5 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000005598 139.0
HFD2_k127_2274258_6 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000004075 116.0
HFD2_k127_2274258_7 PA26 p53-induced protein (sestrin) - - - 0.00000000000000000000002639 109.0
HFD2_k127_2274258_8 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004315 101.0
HFD2_k127_2315411_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 407.0
HFD2_k127_2315411_1 Tricorn protease homolog K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000672 268.0
HFD2_k127_2315411_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000357 207.0
HFD2_k127_2316040_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 447.0
HFD2_k127_2316040_1 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 377.0
HFD2_k127_2316040_2 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000051 241.0
HFD2_k127_2316040_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000001587 169.0
HFD2_k127_2316040_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000001858 123.0
HFD2_k127_2316040_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K21062 - 3.5.4.22 0.000000000000000000000000003996 114.0
HFD2_k127_2338363_0 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000389 260.0
HFD2_k127_2338363_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002963 246.0
HFD2_k127_2338363_2 antisigma factor binding K04749 - - 0.000000000000000000000000841 107.0
HFD2_k127_2338363_3 anti-sigma regulatory factor K04757 - 2.7.11.1 0.000000000000000003994 92.0
HFD2_k127_2339119_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 346.0
HFD2_k127_2339119_1 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.00000000000000000000000000000000000199 146.0
HFD2_k127_2339119_2 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000002596 124.0
HFD2_k127_2346517_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003681 278.0
HFD2_k127_2346517_1 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000005239 254.0
HFD2_k127_2346517_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000007646 136.0
HFD2_k127_2355451_0 Beta-galactosidase - - - 9.57e-243 773.0
HFD2_k127_2357815_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.475e-271 847.0
HFD2_k127_2357815_1 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 407.0
HFD2_k127_2357815_2 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001261 276.0
HFD2_k127_2357815_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
HFD2_k127_2357815_4 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000001194 177.0
HFD2_k127_2357815_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000001433 133.0
HFD2_k127_2357815_7 Antioxidant, AhpC Tsa family K03386 - 1.11.1.15 0.00000000001858 68.0
HFD2_k127_2357815_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000001292 68.0
HFD2_k127_2357815_9 Protein of unknown function, DUF393 - - - 0.0000000005498 63.0
HFD2_k127_2383637_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000005296 213.0
HFD2_k127_2383637_1 - - - - 0.000000000000000000000000000002953 125.0
HFD2_k127_2415076_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 561.0
HFD2_k127_2415076_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 525.0
HFD2_k127_2415076_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 396.0
HFD2_k127_2415076_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 391.0
HFD2_k127_2415076_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000008313 227.0
HFD2_k127_2415076_5 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000005017 154.0
HFD2_k127_2415076_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000009411 98.0
HFD2_k127_2428016_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 484.0
HFD2_k127_2428016_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 394.0
HFD2_k127_2428016_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000001755 205.0
HFD2_k127_2428016_3 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000006979 190.0
HFD2_k127_2428016_4 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000007038 72.0
HFD2_k127_2431844_0 Protein kinase domain K12132 - 2.7.11.1 1.448e-270 859.0
HFD2_k127_2431844_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.296e-195 646.0
HFD2_k127_2431844_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 343.0
HFD2_k127_2431844_3 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000001788 237.0
HFD2_k127_2456533_0 GMC oxidoreductase - - - 1.995e-228 720.0
HFD2_k127_2456533_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 2.059e-221 712.0
HFD2_k127_2456533_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 449.0
HFD2_k127_2456533_3 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 426.0
HFD2_k127_2456533_4 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
HFD2_k127_2456533_5 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000314 164.0
HFD2_k127_2456533_6 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000003082 139.0
HFD2_k127_2464909_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1658.0
HFD2_k127_2467461_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 324.0
HFD2_k127_2467461_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005143 245.0
HFD2_k127_2467461_2 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
HFD2_k127_2467461_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000002764 194.0
HFD2_k127_2467461_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000004677 147.0
HFD2_k127_2467461_5 carboxymuconolactone decarboxylase - - - 0.0000000000000000000007086 98.0
HFD2_k127_2467461_6 DUF218 domain - - - 0.00000000000000002433 91.0
HFD2_k127_2467461_7 Integral membrane protein TerC family - - - 0.000000000000005324 78.0
HFD2_k127_2467461_8 Recombinase zinc beta ribbon domain - - - 0.00008544 47.0
HFD2_k127_2484239_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 317.0
HFD2_k127_2484239_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009254 256.0
HFD2_k127_2505399_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 480.0
HFD2_k127_2505399_1 - - - - 0.00000000000000000000000000000000000000003088 168.0
HFD2_k127_2505399_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000001643 129.0
HFD2_k127_2505399_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000001787 83.0
HFD2_k127_2514695_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000003818 198.0
HFD2_k127_2516679_0 PFAM glycosyl transferase, family 51 K05365 - 2.4.1.129,3.4.16.4 7.593e-213 691.0
HFD2_k127_2516679_1 PFAM Cytochrome C - - - 0.0007833 48.0
HFD2_k127_2517607_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 443.0
HFD2_k127_2517607_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
HFD2_k127_2522959_0 response regulator, receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 456.0
HFD2_k127_2522959_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 377.0
HFD2_k127_2522959_2 - - - - 0.0000000000000000000000000000000000000002332 154.0
HFD2_k127_2522959_3 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000042 141.0
HFD2_k127_2536561_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 367.0
HFD2_k127_2536561_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006995 276.0
HFD2_k127_2536561_2 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
HFD2_k127_2536561_3 PFAM beta-lactamase domain protein - - - 0.0000000004549 63.0
HFD2_k127_2559554_0 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 323.0
HFD2_k127_2559554_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 304.0
HFD2_k127_2559554_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000001107 200.0
HFD2_k127_2559554_3 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000007179 192.0
HFD2_k127_2559554_4 dehydrogenases and related proteins - - - 0.0000000000008661 71.0
HFD2_k127_2561990_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 289.0
HFD2_k127_2561990_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000007089 257.0
HFD2_k127_2561990_2 membrane protein, hemolysin III homolog K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005751 153.0
HFD2_k127_2588388_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 5.738e-207 653.0
HFD2_k127_2588388_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 457.0
HFD2_k127_2588388_10 Fibronectin type III domain protein - - - 0.000000000000000000000000000526 128.0
HFD2_k127_2588388_11 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000001437 89.0
HFD2_k127_2588388_14 - - - - 0.000215 44.0
HFD2_k127_2588388_15 - - - - 0.0007658 47.0
HFD2_k127_2588388_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 441.0
HFD2_k127_2588388_3 Short-chain dehydrogenase reductase SDR K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 405.0
HFD2_k127_2588388_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 299.0
HFD2_k127_2588388_5 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002501 292.0
HFD2_k127_2588388_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000006697 245.0
HFD2_k127_2588388_7 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000002654 231.0
HFD2_k127_2588388_8 Transaldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000001579 202.0
HFD2_k127_2588388_9 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000007396 163.0
HFD2_k127_2600941_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
HFD2_k127_2600941_1 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 315.0
HFD2_k127_2600941_2 - K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000006506 253.0
HFD2_k127_2600941_3 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000005278 231.0
HFD2_k127_2600941_4 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000276 233.0
HFD2_k127_2600941_5 lysyltransferase activity - - - 0.000000000000000000000000000000000000000000000002335 186.0
HFD2_k127_2600941_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000006985 116.0
HFD2_k127_2600941_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000009032 90.0
HFD2_k127_2612103_0 Sortilin, neurotensin receptor 3, - - - 0.0 1118.0
HFD2_k127_2612103_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 2.016e-302 939.0
HFD2_k127_2612103_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 427.0
HFD2_k127_2612103_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000004301 193.0
HFD2_k127_2612103_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000003168 160.0
HFD2_k127_2612103_5 PFAM Nickel cobalt transporter, high-affinity - - - 0.000000000000000000000000000000000006527 147.0
HFD2_k127_2642922_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 416.0
HFD2_k127_2642922_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001131 281.0
HFD2_k127_2642922_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000001036 131.0
HFD2_k127_2642922_3 - - - - 0.00000000000000000000002165 113.0
HFD2_k127_2657891_0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000005326 149.0
HFD2_k127_2657891_1 - - - - 0.000000000000003707 84.0
HFD2_k127_2657891_2 ThiS family - - - 0.000000000000009754 76.0
HFD2_k127_2657891_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000004605 60.0
HFD2_k127_2673838_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 469.0
HFD2_k127_2673838_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000002478 196.0
HFD2_k127_2680656_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 385.0
HFD2_k127_2680656_1 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002867 271.0
HFD2_k127_2680656_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000001449 156.0
HFD2_k127_2680656_3 endonuclease activity K06877 - - 0.0000000000000000000000000000000000000001205 160.0
HFD2_k127_2680656_4 Domain of unknown function (DUF4149) - - - 0.0006651 43.0
HFD2_k127_2681637_0 Tricorn protease C1 domain K08676 - - 0.0 1348.0
HFD2_k127_2681637_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 511.0
HFD2_k127_2681637_11 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000001768 80.0
HFD2_k127_2681637_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000001773 73.0
HFD2_k127_2681637_13 Class III cytochrome C family - - - 0.0000000005604 68.0
HFD2_k127_2681637_14 PFAM O-antigen polymerase - - - 0.0000003099 63.0
HFD2_k127_2681637_15 PFAM Glycosyl transferase family 2 - - - 0.0000214 53.0
HFD2_k127_2681637_2 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000005632 224.0
HFD2_k127_2681637_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000002615 139.0
HFD2_k127_2681637_4 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000001103 146.0
HFD2_k127_2681637_5 MviN-like protein K03980 - - 0.000000000000000000000001067 120.0
HFD2_k127_2681637_6 Glycosyl transferase - - - 0.000000000000000000000007825 118.0
HFD2_k127_2681637_7 methyltransferase - - - 0.0000000000000000000001698 113.0
HFD2_k127_2681637_8 Tetratricopeptide repeat - - - 0.00000000000000001208 96.0
HFD2_k127_2681637_9 COG0457 FOG TPR repeat - - - 0.0000000000000001243 91.0
HFD2_k127_2703711_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.824e-198 632.0
HFD2_k127_2703711_1 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 401.0
HFD2_k127_2703711_2 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 385.0
HFD2_k127_2703711_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000001415 143.0
HFD2_k127_2703711_4 thiolester hydrolase activity K06889 - - 0.00000000001084 76.0
HFD2_k127_2706645_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 3.115e-209 687.0
HFD2_k127_2706645_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 335.0
HFD2_k127_2706645_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 299.0
HFD2_k127_2706645_3 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001936 282.0
HFD2_k127_2706645_4 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000151 199.0
HFD2_k127_2706645_5 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000001669 180.0
HFD2_k127_2706645_6 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000124 136.0
HFD2_k127_2706645_7 repeat protein - - - 0.000000000000000000000009912 107.0
HFD2_k127_2706645_8 membrane K08978 - - 0.000000000000000000000107 104.0
HFD2_k127_2706645_9 EamA-like transporter family - - - 0.0000000000006429 78.0
HFD2_k127_2721683_1 Amino acid permease - - - 0.00000000000000000000000000000000001244 143.0
HFD2_k127_272406_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 331.0
HFD2_k127_272406_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001215 277.0
HFD2_k127_272406_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
HFD2_k127_272406_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000032 238.0
HFD2_k127_272406_4 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000689 221.0
HFD2_k127_272406_5 Alpha beta - - - 0.000000000001243 78.0
HFD2_k127_2728722_0 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 293.0
HFD2_k127_2728722_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
HFD2_k127_2728722_2 - - - - 0.000000000000000000000000007075 114.0
HFD2_k127_2728722_3 Protein of unknown function (DUF433) - - - 0.00000000000000000001824 93.0
HFD2_k127_2728722_4 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000002285 82.0
HFD2_k127_2734959_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 327.0
HFD2_k127_2734959_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000007564 237.0
HFD2_k127_2734959_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000108 200.0
HFD2_k127_2734959_3 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000007948 193.0
HFD2_k127_2734959_4 AntiSigma factor - - - 0.0000000000000000009891 98.0
HFD2_k127_2734959_5 GIY-YIG catalytic domain - - - 0.0000000000000001001 82.0
HFD2_k127_2734959_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000004651 57.0
HFD2_k127_2734959_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000682 47.0
HFD2_k127_2763351_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002172 264.0
HFD2_k127_2763351_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003566 254.0
HFD2_k127_2763351_2 Glycosyltransferase like family 2 - - - 0.0000671 52.0
HFD2_k127_2763548_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 1.772e-200 634.0
HFD2_k127_2763548_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 569.0
HFD2_k127_2763548_2 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 499.0
HFD2_k127_2763548_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 332.0
HFD2_k127_2763548_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000005577 196.0
HFD2_k127_2763548_5 - - - - 0.000000000000000000000000000000000000001745 153.0
HFD2_k127_2763548_6 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000000000000000003596 124.0
HFD2_k127_2779546_0 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 463.0
HFD2_k127_2779546_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 407.0
HFD2_k127_2779546_10 - - - - 0.000000000000001053 79.0
HFD2_k127_2779546_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 342.0
HFD2_k127_2779546_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003314 286.0
HFD2_k127_2779546_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000004027 220.0
HFD2_k127_2779546_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
HFD2_k127_2779546_6 Glyoxalase-like domain K04750 - - 0.0000000000000000000000000000000000000000000000000000000003429 206.0
HFD2_k127_2779546_7 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000001643 168.0
HFD2_k127_2779546_8 - - - - 0.000000000000000000000565 102.0
HFD2_k127_2779546_9 Transglycosylase associated protein - - - 0.0000000000000000004981 90.0
HFD2_k127_278280_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
HFD2_k127_278280_1 protein kinase activity - - - 0.00000001532 59.0
HFD2_k127_2793175_0 peptidase - - - 0.0 1067.0
HFD2_k127_2793175_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.79e-213 691.0
HFD2_k127_2793175_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000002135 189.0
HFD2_k127_2793175_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000000000000000000000000000007135 153.0
HFD2_k127_2804369_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 4.76e-213 672.0
HFD2_k127_2804369_1 alpha-l-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 612.0
HFD2_k127_2804369_2 Fibronectin type III-like domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 405.0
HFD2_k127_2804369_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001672 267.0
HFD2_k127_2859518_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 455.0
HFD2_k127_2859518_1 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 307.0
HFD2_k127_2859518_10 Protein of unknown function (DUF2892) - - - 0.0000747 47.0
HFD2_k127_2859518_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000391 260.0
HFD2_k127_2859518_3 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001064 229.0
HFD2_k127_2859518_4 Cupin - - - 0.00000000000000000000000000000000005032 138.0
HFD2_k127_2859518_5 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000003193 135.0
HFD2_k127_2859518_6 Tetratricopeptide repeat - - - 0.00000000000000000000000002696 123.0
HFD2_k127_2859518_7 Protein of unknown function (DUF1232) - - - 0.000000000000000000000008988 106.0
HFD2_k127_2859518_8 Excinuclease abc c subunit domain protein K07461 - - 0.00000001723 58.0
HFD2_k127_2859518_9 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00002315 47.0
HFD2_k127_2860980_0 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 354.0
HFD2_k127_2860980_1 DinB superfamily - - - 0.0000000000000000000000000000000582 131.0
HFD2_k127_2860980_2 Ferric uptake regulator family K03711,K09825 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000002092 107.0
HFD2_k127_2860980_3 - - - - 0.00000000000000002659 88.0
HFD2_k127_2860980_4 RESPONSE REGULATOR receiver - - - 0.000000000006945 70.0
HFD2_k127_2860980_5 Glutaredoxin-like domain (DUF836) - - - 0.000000000229 68.0
HFD2_k127_2862141_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 470.0
HFD2_k127_2862141_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000003233 243.0
HFD2_k127_2862141_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000006699 195.0
HFD2_k127_2928142_0 alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000001634 234.0
HFD2_k127_2928142_1 PFAM Cupin domain - - - 0.000000000000000000000000000000000000000000000006254 184.0
HFD2_k127_2928142_2 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000001209 158.0
HFD2_k127_2940161_0 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
HFD2_k127_2940161_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000743 233.0
HFD2_k127_2941297_0 Phosphotransferase enzyme family - - - 1.19e-233 740.0
HFD2_k127_2946612_0 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000006029 101.0
HFD2_k127_2956938_0 Protein kinase domain K12132 - 2.7.11.1 4.49e-278 882.0
HFD2_k127_2956938_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.868e-200 657.0
HFD2_k127_2956938_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 554.0
HFD2_k127_2956938_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004449 299.0
HFD2_k127_2956938_4 Ku70/Ku80 beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005696 269.0
HFD2_k127_2956938_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000002223 162.0
HFD2_k127_2956938_6 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000247 147.0
HFD2_k127_2956938_7 PFAM von Willebrand factor type A - - - 0.00000000001309 74.0
HFD2_k127_2964594_0 recA bacterial DNA recombination protein - - - 0.00000000000000000000000000000000000000000000000004204 189.0
HFD2_k127_2964594_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000003176 102.0
HFD2_k127_2964594_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000001274 60.0
HFD2_k127_2992477_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 5.53e-231 718.0
HFD2_k127_2992477_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001308 259.0
HFD2_k127_2998774_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 591.0
HFD2_k127_2998774_1 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 454.0
HFD2_k127_2998774_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000001795 154.0
HFD2_k127_2998774_11 TonB C terminal K03832 - - 0.0000000000000000000000000000000006582 141.0
HFD2_k127_2998774_12 Cupin domain - - - 0.0000000000000001379 88.0
HFD2_k127_2998774_2 ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 408.0
HFD2_k127_2998774_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 303.0
HFD2_k127_2998774_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 304.0
HFD2_k127_2998774_5 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002089 259.0
HFD2_k127_2998774_6 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
HFD2_k127_2998774_7 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000003827 195.0
HFD2_k127_2998774_8 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000006325 190.0
HFD2_k127_2998774_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000003179 179.0
HFD2_k127_3010127_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 3.033e-212 674.0
HFD2_k127_3010127_1 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
HFD2_k127_3010127_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005433 242.0
HFD2_k127_3010127_3 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000256 107.0
HFD2_k127_3016319_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 369.0
HFD2_k127_3016319_1 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003582 260.0
HFD2_k127_3016319_11 XdhC and CoxI family K07402 - - 0.000000000003094 68.0
HFD2_k127_3016319_12 cellulase activity - - - 0.000000000014 78.0
HFD2_k127_3016319_2 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001652 249.0
HFD2_k127_3016319_3 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001172 268.0
HFD2_k127_3016319_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000001294 216.0
HFD2_k127_3016319_5 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000005978 124.0
HFD2_k127_3016319_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000008052 116.0
HFD2_k127_3016319_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000837 114.0
HFD2_k127_3016319_8 Protein of unknown function (DUF507) - - - 0.000000000000000000000002974 104.0
HFD2_k127_3016319_9 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000003748 104.0
HFD2_k127_3020258_0 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 612.0
HFD2_k127_3020258_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000005499 136.0
HFD2_k127_3039882_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 600.0
HFD2_k127_3039882_1 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 428.0
HFD2_k127_3039882_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 426.0
HFD2_k127_3039882_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003229 284.0
HFD2_k127_3039882_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000002194 188.0
HFD2_k127_3039882_5 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000000000171 158.0
HFD2_k127_3039882_6 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000000000000000000000004641 147.0
HFD2_k127_3039882_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000003844 133.0
HFD2_k127_3039882_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000005144 104.0
HFD2_k127_3039882_9 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000001062 103.0
HFD2_k127_3082486_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 590.0
HFD2_k127_3082486_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 332.0
HFD2_k127_3082486_2 - - - - 0.00000000000000000000000000000002443 134.0
HFD2_k127_3086887_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 590.0
HFD2_k127_3086887_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 446.0
HFD2_k127_3086887_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005693 261.0
HFD2_k127_3086887_3 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000904 145.0
HFD2_k127_3086887_4 Domain of unknown function (DUF4198) - - - 0.0000000000000000000000000000008179 134.0
HFD2_k127_3086887_5 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000001503 59.0
HFD2_k127_3086887_6 peptidyl-tyrosine sulfation - - - 0.0000003987 63.0
HFD2_k127_3089821_0 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 417.0
HFD2_k127_3089821_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000006683 187.0
HFD2_k127_3105946_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
HFD2_k127_3108794_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 305.0
HFD2_k127_3108794_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000006807 126.0
HFD2_k127_3115840_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.4e-248 778.0
HFD2_k127_3115840_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 524.0
HFD2_k127_3115840_10 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000005088 214.0
HFD2_k127_3115840_11 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000001008 201.0
HFD2_k127_3115840_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000006572 202.0
HFD2_k127_3115840_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000002288 165.0
HFD2_k127_3115840_14 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000002475 139.0
HFD2_k127_3115840_15 Peptidase family M1 domain - - - 0.00000000000000000005944 100.0
HFD2_k127_3115840_16 VWA domain containing CoxE-like protein - - - 0.000000000000000007994 94.0
HFD2_k127_3115840_17 - - - - 0.00000000000000003831 84.0
HFD2_k127_3115840_18 COG0457 FOG TPR repeat - - - 0.0000000000007203 82.0
HFD2_k127_3115840_2 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 511.0
HFD2_k127_3115840_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 441.0
HFD2_k127_3115840_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 388.0
HFD2_k127_3115840_5 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 332.0
HFD2_k127_3115840_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000354 261.0
HFD2_k127_3115840_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000003635 245.0
HFD2_k127_3115840_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002944 237.0
HFD2_k127_3115840_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000335 246.0
HFD2_k127_3121670_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 391.0
HFD2_k127_3121670_1 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
HFD2_k127_312394_0 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007806 252.0
HFD2_k127_312394_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000007664 150.0
HFD2_k127_3127190_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 503.0
HFD2_k127_3127190_1 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 380.0
HFD2_k127_3127190_2 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 335.0
HFD2_k127_3127190_3 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 333.0
HFD2_k127_3127190_4 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001014 265.0
HFD2_k127_3127190_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000001155 233.0
HFD2_k127_3127190_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000004528 226.0
HFD2_k127_3127190_7 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000004457 146.0
HFD2_k127_3127190_8 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.000000000000000000004947 100.0
HFD2_k127_3127190_9 Domain of unknown function (DUF4340) - - - 0.00000000000000002236 94.0
HFD2_k127_315330_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 397.0
HFD2_k127_315330_1 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 314.0
HFD2_k127_315330_2 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002613 281.0
HFD2_k127_315330_3 - - - - 0.000000000000000000000000000000000003925 142.0
HFD2_k127_315330_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00005684 46.0
HFD2_k127_3182428_0 Carboxypeptidase regulatory-like domain - - - 5e-324 1029.0
HFD2_k127_3182428_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 4.353e-226 734.0
HFD2_k127_3182428_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 535.0
HFD2_k127_3182428_3 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
HFD2_k127_3182428_4 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004259 261.0
HFD2_k127_3182428_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000007073 168.0
HFD2_k127_3182428_6 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000004593 141.0
HFD2_k127_3182428_7 - - - - 0.000000000000072 78.0
HFD2_k127_3188999_0 Sortilin, neurotensin receptor 3, - - - 0.0 1091.0
HFD2_k127_3189137_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 413.0
HFD2_k127_3189137_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 377.0
HFD2_k127_3189137_2 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000003463 231.0
HFD2_k127_3189137_3 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000006841 230.0
HFD2_k127_3189137_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000002477 142.0
HFD2_k127_3189137_5 - - - - 0.0000000003003 71.0
HFD2_k127_3189137_6 Restriction endonuclease BglII - - - 0.0000002412 59.0
HFD2_k127_3191900_0 Amino acid permease - - - 1.368e-212 674.0
HFD2_k127_3191900_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000001407 237.0
HFD2_k127_3191900_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000006377 127.0
HFD2_k127_3196339_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.699e-208 655.0
HFD2_k127_3196339_1 PFAM Amidohydrolase 3 - - - 0.000000000000000001485 91.0
HFD2_k127_3200473_0 hydrolase family, 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 561.0
HFD2_k127_3200473_1 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.0000000000000000000000000000000000000000000000000000000001492 218.0
HFD2_k127_3200473_2 GDP-mannose K01711 GO:0000902,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008446,GO:0009058,GO:0009225,GO:0009226,GO:0009653,GO:0009826,GO:0009987,GO:0016043,GO:0016049,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0032502,GO:0032989,GO:0034641,GO:0034654,GO:0040007,GO:0042350,GO:0042351,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046368,GO:0046483,GO:0048589,GO:0048856,GO:0048869,GO:0055086,GO:0060560,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 4.2.1.47 0.000000000000000006561 85.0
HFD2_k127_3207381_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000002884 180.0
HFD2_k127_3207381_1 Alginate export - - - 0.000000000000000000000000000000000000000000002591 181.0
HFD2_k127_3207381_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000001045 166.0
HFD2_k127_3207381_3 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000002512 111.0
HFD2_k127_3207381_4 Domain of unknown function (DUF1858) - - - 0.0000000000000000007202 92.0
HFD2_k127_3207869_0 Uncharacterized protein family (UPF0051) K09014 - - 2.468e-285 882.0
HFD2_k127_3207869_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 582.0
HFD2_k127_3207869_10 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000003296 224.0
HFD2_k127_3207869_11 - - - - 0.00000000000000000000000000000000000000000000000000000000002843 214.0
HFD2_k127_3207869_12 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
HFD2_k127_3207869_13 DoxX - - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HFD2_k127_3207869_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000134 172.0
HFD2_k127_3207869_15 Transcriptional regulator - - - 0.000000000000000000000000000000000001177 144.0
HFD2_k127_3207869_16 - - - - 0.0000000000000000000000000005205 117.0
HFD2_k127_3207869_17 dUTP biosynthetic process K01494,K01520 - 3.5.4.13,3.6.1.23 0.00000000000000000000000268 110.0
HFD2_k127_3207869_18 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000007863 85.0
HFD2_k127_3207869_19 Sporulation and spore germination - - - 0.0000000000004386 78.0
HFD2_k127_3207869_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 426.0
HFD2_k127_3207869_20 ETC complex I subunit K00329 - 1.6.5.3 0.0001516 48.0
HFD2_k127_3207869_3 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 407.0
HFD2_k127_3207869_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 332.0
HFD2_k127_3207869_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 310.0
HFD2_k127_3207869_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 301.0
HFD2_k127_3207869_7 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003167 282.0
HFD2_k127_3207869_8 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 256.0
HFD2_k127_3207869_9 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000000000000009628 222.0
HFD2_k127_3214432_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 323.0
HFD2_k127_3214432_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 307.0
HFD2_k127_3214432_2 Trehalase K03931 - - 0.00000000000000000000000000000000000000000000000000000000001231 228.0
HFD2_k127_3214432_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000001497 144.0
HFD2_k127_321488_0 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000004218 239.0
HFD2_k127_321488_1 PFAM M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HFD2_k127_3240625_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001989 271.0
HFD2_k127_3240625_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000006686 187.0
HFD2_k127_3251899_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 346.0
HFD2_k127_3251899_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000008438 198.0
HFD2_k127_3251899_2 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000002388 175.0
HFD2_k127_3251899_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00002225 51.0
HFD2_k127_3286359_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 534.0
HFD2_k127_3286359_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 502.0
HFD2_k127_3286359_10 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000001602 215.0
HFD2_k127_3286359_11 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000003926 201.0
HFD2_k127_3286359_12 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000005627 212.0
HFD2_k127_3286359_13 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000001364 187.0
HFD2_k127_3286359_14 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000001805 204.0
HFD2_k127_3286359_15 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000005115 151.0
HFD2_k127_3286359_16 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000008584 153.0
HFD2_k127_3286359_17 - - - - 0.0000000000000000000000000000000169 145.0
HFD2_k127_3286359_18 50s ribosomal protein l31 K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000001865 59.0
HFD2_k127_3286359_19 - - - - 0.0000000164 66.0
HFD2_k127_3286359_2 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 496.0
HFD2_k127_3286359_20 - - - - 0.00009075 51.0
HFD2_k127_3286359_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 490.0
HFD2_k127_3286359_4 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 365.0
HFD2_k127_3286359_5 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 366.0
HFD2_k127_3286359_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 315.0
HFD2_k127_3286359_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
HFD2_k127_3286359_8 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 304.0
HFD2_k127_3286359_9 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000005575 235.0
HFD2_k127_3297215_0 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 414.0
HFD2_k127_3297215_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000725 149.0
HFD2_k127_3316487_0 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000001996 202.0
HFD2_k127_3316487_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000009262 162.0
HFD2_k127_3316487_2 YjbR - - - 0.00000000000000000000000000000000000000005329 154.0
HFD2_k127_3337103_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 546.0
HFD2_k127_3337103_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000004234 233.0
HFD2_k127_3337103_2 - - - - 0.0000000000000000000000009709 110.0
HFD2_k127_3338726_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 521.0
HFD2_k127_3338726_1 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.00000000000000000000000000000000000000000000000000000001256 202.0
HFD2_k127_3338726_2 Methylase involved in ubiquinone menaquinone biosynthesis K07755 - 2.1.1.137 0.0000000000000000000000000000000000000006678 151.0
HFD2_k127_3340961_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.204e-248 781.0
HFD2_k127_3340961_1 AMP-binding enzyme K00666 - - 4.025e-221 718.0
HFD2_k127_3340961_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 329.0
HFD2_k127_3340961_3 - - - - 0.0000000000000000000000000000000000000000000000000000002833 200.0
HFD2_k127_3340961_4 DinB superfamily - - - 0.000000000000000000000000000000000000001284 154.0
HFD2_k127_3340961_5 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000008475 131.0
HFD2_k127_3340961_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000125 119.0
HFD2_k127_3340961_7 TIGRFAM TonB K03832 - - 0.000000000001504 68.0
HFD2_k127_3365297_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 338.0
HFD2_k127_3365297_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
HFD2_k127_3365297_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
HFD2_k127_3365297_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000002865 224.0
HFD2_k127_3365297_4 Sporulation related domain - - - 0.000000000001216 76.0
HFD2_k127_3365297_5 prohibitin homologues - - - 0.0001622 48.0
HFD2_k127_3365297_6 Tetratricopeptide repeat - - - 0.0001765 46.0
HFD2_k127_3367115_0 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 347.0
HFD2_k127_3367115_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000125 265.0
HFD2_k127_3367115_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006389 257.0
HFD2_k127_3367115_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000002376 134.0
HFD2_k127_3367115_4 PAS fold - - - 0.0000003651 58.0
HFD2_k127_3367115_5 - - - - 0.00002145 57.0
HFD2_k127_3370865_0 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 305.0
HFD2_k127_3376857_0 serine-type peptidase activity K01278,K06889 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 351.0
HFD2_k127_3376857_1 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 328.0
HFD2_k127_3376857_2 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000102 149.0
HFD2_k127_3376857_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000804 137.0
HFD2_k127_3376857_4 - - - - 0.000000000000000000005875 96.0
HFD2_k127_3396512_0 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 398.0
HFD2_k127_3396512_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000001189 148.0
HFD2_k127_3396512_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000003985 153.0
HFD2_k127_3399296_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 412.0
HFD2_k127_3399296_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 306.0
HFD2_k127_3399296_2 - - - - 0.00000000000000000000000000000006983 134.0
HFD2_k127_3399296_3 - - - - 0.000001435 54.0
HFD2_k127_3399296_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00001662 55.0
HFD2_k127_344744_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 591.0
HFD2_k127_344744_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000002274 155.0
HFD2_k127_3450147_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 580.0
HFD2_k127_3450147_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002406 279.0
HFD2_k127_3450147_2 3-oxoacid CoA-transferase, a subunit K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000006808 210.0
HFD2_k127_3450147_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000004825 183.0
HFD2_k127_3450147_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000001229 147.0
HFD2_k127_3450147_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000001352 134.0
HFD2_k127_3450147_6 chorismate mutase domain of gram positive AroA protein K13853 - 2.5.1.54,5.4.99.5 0.00000000945 62.0
HFD2_k127_3452468_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 2.018e-239 755.0
HFD2_k127_3452468_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.25e-207 679.0
HFD2_k127_3452468_10 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000002049 92.0
HFD2_k127_3452468_2 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 585.0
HFD2_k127_3452468_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 587.0
HFD2_k127_3452468_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 379.0
HFD2_k127_3452468_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001965 276.0
HFD2_k127_3452468_6 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 259.0
HFD2_k127_3452468_7 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000806 217.0
HFD2_k127_3452468_8 Ribose/Galactose Isomerase K01808,K01819,K21911 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.26,5.3.1.34,5.3.1.6 0.0000000000000000000000000000000000000000000001569 172.0
HFD2_k127_3452468_9 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.00000000000000000000000000000000000000005729 160.0
HFD2_k127_3463478_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 538.0
HFD2_k127_3463478_1 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 531.0
HFD2_k127_3463478_2 polysaccharide export K01991,K20988 - - 0.00000000000000000000000000000000000000000000001681 184.0
HFD2_k127_3463478_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000001234 163.0
HFD2_k127_3463478_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000002172 89.0
HFD2_k127_3465663_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 9.991e-272 849.0
HFD2_k127_3465663_1 Bacterial protein of unknown function (DUF885) - - - 1.749e-194 629.0
HFD2_k127_3465663_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 375.0
HFD2_k127_350254_0 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000396 292.0
HFD2_k127_350254_1 Single Cache domain 2 K02480 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002069 222.0
HFD2_k127_350254_2 PFAM KaiB domain K08481 - - 0.00000000000000003861 85.0
HFD2_k127_3524856_0 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 493.0
HFD2_k127_3524856_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 312.0
HFD2_k127_3524856_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000002995 122.0
HFD2_k127_3524856_3 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000005688 126.0
HFD2_k127_3529450_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 496.0
HFD2_k127_3529450_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 510.0
HFD2_k127_3529450_10 Putative phosphatase (DUF442) - - - 0.000000000000000001071 93.0
HFD2_k127_3529450_11 isomerase activity K01821 - 5.3.2.6 0.00000000000006836 74.0
HFD2_k127_3529450_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000009677 56.0
HFD2_k127_3529450_13 Putative zinc-finger - - - 0.0001093 52.0
HFD2_k127_3529450_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000279 292.0
HFD2_k127_3529450_3 membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000302 273.0
HFD2_k127_3529450_4 thiolester hydrolase activity K07000 - - 0.000000000000000000000000000000000000000000000000000001925 200.0
HFD2_k127_3529450_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000004655 188.0
HFD2_k127_3529450_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000001062 152.0
HFD2_k127_3529450_7 competence protein - - - 0.0000000000000000000000000000000000002148 154.0
HFD2_k127_3529450_8 Reverse transcriptase-like - - - 0.000000000000000000000000000000000003511 145.0
HFD2_k127_3529450_9 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000004346 129.0
HFD2_k127_3533554_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 592.0
HFD2_k127_3533554_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 537.0
HFD2_k127_3533554_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 349.0
HFD2_k127_3533554_3 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002752 282.0
HFD2_k127_3539215_0 efflux transmembrane transporter activity K02004 - - 7.798e-216 696.0
HFD2_k127_3539215_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
HFD2_k127_3539215_2 - - - - 0.000000000000000000000000000000000000000000000000000003552 202.0
HFD2_k127_3546709_0 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 445.0
HFD2_k127_3546709_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
HFD2_k127_3555070_0 PFAM peptidase U62 modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 572.0
HFD2_k127_3555070_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 427.0
HFD2_k127_3555070_2 PFAM Redoxin - - - 0.0000000000000000000000000000000000472 146.0
HFD2_k127_3555070_3 glycosyl transferase family 2 - - - 0.00000000000000001036 91.0
HFD2_k127_3562237_0 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 319.0
HFD2_k127_3597940_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 443.0
HFD2_k127_3597940_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001817 246.0
HFD2_k127_3597940_2 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000019 108.0
HFD2_k127_3597940_3 - - - - 0.000000002131 61.0
HFD2_k127_361544_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1316.0
HFD2_k127_3640529_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 1.567e-194 628.0
HFD2_k127_3640529_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001513 280.0
HFD2_k127_3640529_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000001249 198.0
HFD2_k127_3640529_3 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000004776 153.0
HFD2_k127_3640529_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000000000001182 82.0
HFD2_k127_3649582_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 562.0
HFD2_k127_3649582_1 Mu-like prophage FluMu protein gp28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 410.0
HFD2_k127_3649582_2 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 328.0
HFD2_k127_3649582_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000228 195.0
HFD2_k127_3649582_4 - - - - 0.000000000000002034 85.0
HFD2_k127_3652736_0 Ribosomal protein S1 K02945 - - 2.275e-194 629.0
HFD2_k127_3652736_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 448.0
HFD2_k127_3652736_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 434.0
HFD2_k127_3652736_3 excinuclease ABC activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 271.0
HFD2_k127_3652736_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001365 264.0
HFD2_k127_3652736_5 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000001033 221.0
HFD2_k127_3652736_6 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000001824 203.0
HFD2_k127_3652736_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000004411 147.0
HFD2_k127_3652736_8 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000000297 145.0
HFD2_k127_3652736_9 - - - - 0.000005975 57.0
HFD2_k127_3675968_0 PFAM ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 593.0
HFD2_k127_3675968_1 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 387.0
HFD2_k127_3675968_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 333.0
HFD2_k127_3675968_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000001072 123.0
HFD2_k127_3700696_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 434.0
HFD2_k127_3700696_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000001274 124.0
HFD2_k127_3700696_2 Las17-binding protein actin regulator - - - 0.000000000000000000006194 94.0
HFD2_k127_3701179_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 410.0
HFD2_k127_3701179_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002269 248.0
HFD2_k127_371301_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
HFD2_k127_371301_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003013 263.0
HFD2_k127_37134_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 315.0
HFD2_k127_37134_1 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000000001921 152.0
HFD2_k127_37134_2 Pentapeptide repeats (9 copies) - - - 0.0000000000000007196 90.0
HFD2_k127_3740463_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 320.0
HFD2_k127_3740463_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007935 284.0
HFD2_k127_3740463_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002711 265.0
HFD2_k127_3740463_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000001276 87.0
HFD2_k127_3740463_4 - - - - 0.0000000000002242 80.0
HFD2_k127_3746996_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 475.0
HFD2_k127_3746996_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 340.0
HFD2_k127_3746996_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 308.0
HFD2_k127_3746996_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004382 228.0
HFD2_k127_3746996_4 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000003096 210.0
HFD2_k127_3746996_5 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000001946 177.0
HFD2_k127_3746996_6 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000113 114.0
HFD2_k127_3746996_8 Involved in the tonB-independent uptake of proteins - - - 0.000000002111 70.0
HFD2_k127_3767452_0 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 376.0
HFD2_k127_3767452_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 297.0
HFD2_k127_3767452_2 sequence-specific DNA binding K03719 - - 0.0000000000000000000000000000000000000001016 165.0
HFD2_k127_3767452_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000005684 137.0
HFD2_k127_3767452_4 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000002064 127.0
HFD2_k127_3836845_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0 1071.0
HFD2_k127_3836845_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 537.0
HFD2_k127_3836845_2 antisigma factor binding K03409,K04749,K07122 - - 0.000000000000000001843 91.0
HFD2_k127_3868259_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 471.0
HFD2_k127_3868259_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000881 290.0
HFD2_k127_3868259_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
HFD2_k127_3868259_3 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000005148 234.0
HFD2_k127_3868259_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000003495 149.0
HFD2_k127_3868259_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000005508 89.0
HFD2_k127_3868259_6 Transglutaminase-like superfamily - - - 0.0000000000004035 77.0
HFD2_k127_3907755_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 502.0
HFD2_k127_3907755_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 313.0
HFD2_k127_3907755_2 Putative beta-lactamase-inhibitor-like, PepSY-like - - - 0.0000000000000000000005596 103.0
HFD2_k127_3910056_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.346e-200 649.0
HFD2_k127_3910056_1 oxidoreductase activity - - - 0.000000000000000000001663 108.0
HFD2_k127_394204_0 Elongation factor G, domain IV K02355 - - 1.187e-229 725.0
HFD2_k127_394204_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 1.185e-205 648.0
HFD2_k127_394204_2 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 317.0
HFD2_k127_394204_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000007221 222.0
HFD2_k127_394204_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000007493 181.0
HFD2_k127_394204_5 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000001734 175.0
HFD2_k127_3942536_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 590.0
HFD2_k127_3942536_1 NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 310.0
HFD2_k127_3942536_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001552 232.0
HFD2_k127_3942536_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000001139 207.0
HFD2_k127_3942536_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000001511 165.0
HFD2_k127_3942536_5 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000008512 149.0
HFD2_k127_3942536_6 Aminoacyl-tRNA editing domain K19055 - - 0.00000004023 61.0
HFD2_k127_3951003_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002638 247.0
HFD2_k127_3951003_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001967 209.0
HFD2_k127_3951003_2 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000007702 180.0
HFD2_k127_3951003_3 Leucine rich repeat variant - - - 0.0001574 51.0
HFD2_k127_3951003_4 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 0.0006373 44.0
HFD2_k127_3957872_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 519.0
HFD2_k127_3957872_1 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002308 280.0
HFD2_k127_3957872_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000001836 226.0
HFD2_k127_3957872_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000002205 222.0
HFD2_k127_3957872_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000001653 150.0
HFD2_k127_3957872_5 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000003131 112.0
HFD2_k127_3978558_0 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002286 297.0
HFD2_k127_3978558_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000002937 256.0
HFD2_k127_3978558_2 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000005061 166.0
HFD2_k127_3978558_3 glycosyl transferase - - - 0.000001866 52.0
HFD2_k127_4000487_0 Glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 2.191e-290 920.0
HFD2_k127_4000487_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000002167 183.0
HFD2_k127_4005250_0 PFAM Type II secretion system protein E K02652 - - 4.338e-248 775.0
HFD2_k127_4005250_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
HFD2_k127_4005250_2 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000005946 151.0
HFD2_k127_4008189_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.085e-227 715.0
HFD2_k127_4008189_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HFD2_k127_4008189_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000008073 175.0
HFD2_k127_4008189_3 DinB family - - - 0.00000000000000000000000000000000104 137.0
HFD2_k127_4008189_4 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000003383 91.0
HFD2_k127_4008189_5 - - - - 0.000000000000000075 84.0
HFD2_k127_4008189_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.0000000000001414 73.0
HFD2_k127_4008189_8 protein secretion K03116 - - 0.000000000009785 66.0
HFD2_k127_4020668_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 452.0
HFD2_k127_4020668_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 361.0
HFD2_k127_4020668_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 353.0
HFD2_k127_4026136_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 308.0
HFD2_k127_4026136_1 RNA polymerase sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
HFD2_k127_4026136_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000003641 207.0
HFD2_k127_4026136_3 - - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
HFD2_k127_4026136_4 - - - - 0.000000000000000007118 89.0
HFD2_k127_4026136_5 Domain of unknown function (DUF4386) - - - 0.0000000007932 69.0
HFD2_k127_404775_0 Response regulator receiver K07714 - - 9.683e-194 614.0
HFD2_k127_404775_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 585.0
HFD2_k127_404775_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 348.0
HFD2_k127_404775_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 327.0
HFD2_k127_404775_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000004022 222.0
HFD2_k127_404775_5 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000001142 140.0
HFD2_k127_404775_6 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000005081 121.0
HFD2_k127_404775_7 Group 1 truncated hemoglobin K06886 - - 0.0000000000000000000000005963 113.0
HFD2_k127_4048346_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 314.0
HFD2_k127_4048346_1 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000004983 166.0
HFD2_k127_4048346_2 R3H domain K06346 - - 0.000000000000000000000002423 111.0
HFD2_k127_4048346_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000005263 51.0
HFD2_k127_4049310_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 307.0
HFD2_k127_4049310_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
HFD2_k127_4049310_2 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000002271 139.0
HFD2_k127_4049310_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000001938 59.0
HFD2_k127_4062543_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1198.0
HFD2_k127_4062543_1 - - - - 0.0 1145.0
HFD2_k127_4062543_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1048.0
HFD2_k127_4062543_3 Glycogen debranching enzyme - - - 2.16e-289 908.0
HFD2_k127_4062543_4 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 332.0
HFD2_k127_4062543_5 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000005087 64.0
HFD2_k127_4067712_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 4.196e-201 634.0
HFD2_k127_4067712_1 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 452.0
HFD2_k127_4067712_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000002381 223.0
HFD2_k127_4067712_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000007324 158.0
HFD2_k127_4067712_4 PFAM Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000002535 99.0
HFD2_k127_4089101_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 426.0
HFD2_k127_4089101_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000002771 145.0
HFD2_k127_4089101_2 - - - - 0.00000000000000000000000000000000002324 139.0
HFD2_k127_4089101_3 - - - - 0.000007199 51.0
HFD2_k127_4097114_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000007244 197.0
HFD2_k127_4097114_3 COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - 0.00000000000000000000002892 114.0
HFD2_k127_4140660_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000004723 222.0
HFD2_k127_4140660_1 FeoA K03709 - - 0.000000000000000000000000000000000000000000000000000000000006874 217.0
HFD2_k127_4140660_2 Low molecular weight phosphatase family - - - 0.000000000000000000003711 98.0
HFD2_k127_4140660_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000004367 48.0
HFD2_k127_4148562_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000008924 258.0
HFD2_k127_4148562_1 AAA domain - - - 0.000000000000000000000000000000000000005928 153.0
HFD2_k127_4148562_2 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000003129 149.0
HFD2_k127_4148562_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000001335 111.0
HFD2_k127_4148562_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000001289 53.0
HFD2_k127_4224376_0 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001736 255.0
HFD2_k127_4234817_0 Protein of unknown function, DUF255 K06888 - - 7.162e-240 760.0
HFD2_k127_4234817_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 519.0
HFD2_k127_4234817_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 336.0
HFD2_k127_4234817_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 330.0
HFD2_k127_4234817_4 - - - - 0.000000000000000000000000000006287 131.0
HFD2_k127_4234817_5 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000002671 107.0
HFD2_k127_4294665_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000001582 194.0
HFD2_k127_4294665_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000006361 145.0
HFD2_k127_4294665_2 Tetratricopeptide repeat - - - 0.0000000000000000000000002383 117.0
HFD2_k127_4294665_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000004843 113.0
HFD2_k127_4294665_4 Phenazine biosynthesis-like protein - - - 0.00000000000222 70.0
HFD2_k127_4304727_0 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007847 278.0
HFD2_k127_4304727_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000002465 126.0
HFD2_k127_4304727_2 NHL repeat - - - 0.000000000000000000000000000002091 132.0
HFD2_k127_4304727_3 Sh3 type 3 domain protein - - - 0.0000000000001814 82.0
HFD2_k127_4304727_4 Winged helix-turn-helix domain (DUF2582) - - - 0.00000002929 58.0
HFD2_k127_4312989_0 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 423.0
HFD2_k127_4312989_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 346.0
HFD2_k127_4312989_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000007106 208.0
HFD2_k127_4312989_3 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000002794 70.0
HFD2_k127_4319288_0 Carboxypeptidase regulatory-like domain - - - 1.901e-289 928.0
HFD2_k127_4319288_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 455.0
HFD2_k127_4319288_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000003774 205.0
HFD2_k127_4319288_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000002408 153.0
HFD2_k127_4319288_4 Regulatory protein - - - 0.00000000000000000000000009743 111.0
HFD2_k127_4319288_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000006286 111.0
HFD2_k127_4319623_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 613.0
HFD2_k127_4319623_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
HFD2_k127_4319623_2 LemA family K03744 - - 0.0000000000000000000000000000001169 125.0
HFD2_k127_4319623_3 Phospholipid methyltransferase - - - 0.000000000000000000000007915 111.0
HFD2_k127_4319623_4 SnoaL-like domain - - - 0.0001238 49.0
HFD2_k127_4336338_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 614.0
HFD2_k127_4336338_1 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000002755 229.0
HFD2_k127_4336338_2 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000301 185.0
HFD2_k127_4336338_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000006745 109.0
HFD2_k127_4349081_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 353.0
HFD2_k127_4349081_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 322.0
HFD2_k127_4349081_2 Flavin containing amine oxidoreductase - - - 0.0000001051 59.0
HFD2_k127_4349081_3 Flavin containing amine oxidoreductase - - - 0.0000001103 57.0
HFD2_k127_4352417_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 400.0
HFD2_k127_4352417_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
HFD2_k127_4352417_2 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000002082 167.0
HFD2_k127_4352417_3 response to abiotic stimulus K03086 - - 0.0000000000000000000000000000000000000003196 153.0
HFD2_k127_4352417_4 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000008248 145.0
HFD2_k127_4352417_5 Domain of unknown function (DUF4870) - - - 0.000000000000000000000728 101.0
HFD2_k127_4356678_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 413.0
HFD2_k127_4356678_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000004111 231.0
HFD2_k127_4375405_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.197e-243 770.0
HFD2_k127_4375405_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 415.0
HFD2_k127_4375405_10 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000001757 96.0
HFD2_k127_4375405_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 407.0
HFD2_k127_4375405_3 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 338.0
HFD2_k127_4375405_4 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 313.0
HFD2_k127_4375405_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000001138 256.0
HFD2_k127_4375405_6 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000000000000000000005324 221.0
HFD2_k127_4375405_7 ABC transporter (Permease) K02004 - - 0.00000000000000000000000000000000000000000000000000003013 201.0
HFD2_k127_4375405_8 Protein of unknown function (DUF971) - - - 0.000000000000000000000000002988 115.0
HFD2_k127_4375405_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000001242 113.0
HFD2_k127_4377651_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K04108 - 1.3.7.9 2.529e-235 751.0
HFD2_k127_4377651_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 380.0
HFD2_k127_4377651_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000009044 264.0
HFD2_k127_4377651_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000008055 179.0
HFD2_k127_4377651_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000008237 173.0
HFD2_k127_4377651_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000278 156.0
HFD2_k127_4377651_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000006116 115.0
HFD2_k127_4380688_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.736e-253 806.0
HFD2_k127_4380688_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002506 267.0
HFD2_k127_4411933_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 591.0
HFD2_k127_4411933_1 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 580.0
HFD2_k127_4411933_2 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 438.0
HFD2_k127_4411933_3 Cytidine monophosphokinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 259.0
HFD2_k127_4411933_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000833 170.0
HFD2_k127_4411933_5 Chorismate mutase type II K04093 - 5.4.99.5 0.000000004029 64.0
HFD2_k127_4493313_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 338.0
HFD2_k127_4493313_1 membrane transporter protein K07090 - - 0.0000000000000000000000002442 117.0
HFD2_k127_4544842_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 331.0
HFD2_k127_4544842_1 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006728 308.0
HFD2_k127_4690108_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 610.0
HFD2_k127_4719636_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 316.0
HFD2_k127_4719636_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
HFD2_k127_4719636_2 - - - - 0.0000000000000000000000000000000000000000002359 168.0
HFD2_k127_4719636_3 DinB family - - - 0.000000000000000000000000000000000000001768 152.0
HFD2_k127_4719636_4 OsmC-like protein K07397 - - 0.000000000000000000000000005956 115.0
HFD2_k127_4736230_0 Sodium:sulfate symporter transmembrane region K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 487.0
HFD2_k127_4736230_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
HFD2_k127_4736230_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000000002971 149.0
HFD2_k127_476850_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 562.0
HFD2_k127_476850_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 356.0
HFD2_k127_476850_2 cellulose binding - - - 0.000000000000000000000000000000000000000003833 164.0
HFD2_k127_476850_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000002491 74.0
HFD2_k127_4771528_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 499.0
HFD2_k127_4771528_1 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 430.0
HFD2_k127_4771528_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
HFD2_k127_4771528_3 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000001985 119.0
HFD2_k127_4795839_0 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 507.0
HFD2_k127_4795839_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000003764 99.0
HFD2_k127_4827151_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 333.0
HFD2_k127_4827151_1 Osmosensitive K channel His kinase sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 320.0
HFD2_k127_4827151_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000001123 213.0
HFD2_k127_4830291_0 Sodium:solute symporter family - - - 2.222e-216 687.0
HFD2_k127_4830291_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 445.0
HFD2_k127_4830291_2 iron ion homeostasis K05349 - 3.2.1.21 0.0000000000000000000000000001114 130.0
HFD2_k127_4847064_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 387.0
HFD2_k127_4847064_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 299.0
HFD2_k127_4852918_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000008672 246.0
HFD2_k127_4852918_1 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000002966 137.0
HFD2_k127_4852918_2 Amidohydrolase family - - - 0.000000000000004844 76.0
HFD2_k127_4863364_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 3.845e-266 830.0
HFD2_k127_4863364_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.715e-233 740.0
HFD2_k127_4863364_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000005526 251.0
HFD2_k127_4863364_3 Peptidase family M28 - - - 0.0000000000000000000000001262 110.0
HFD2_k127_4863364_4 - - - - 0.00000000000000000004769 92.0
HFD2_k127_4888945_0 peptidase - - - 4.354e-234 744.0
HFD2_k127_4888945_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 538.0
HFD2_k127_4888945_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000005785 230.0
HFD2_k127_4888945_11 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000003832 216.0
HFD2_k127_4888945_12 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000006184 212.0
HFD2_k127_4888945_13 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000005402 169.0
HFD2_k127_4888945_14 - - - - 0.000000000000000000000000000000000000000000001498 173.0
HFD2_k127_4888945_15 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000007662 154.0
HFD2_k127_4888945_16 Helix-turn-helix domain - - - 0.000000000000000000000000000001802 123.0
HFD2_k127_4888945_17 Cold shock protein domain K03704 - - 0.0000000000000000000000000003558 116.0
HFD2_k127_4888945_19 peptidyl-tyrosine sulfation - - - 0.00000000009379 74.0
HFD2_k127_4888945_2 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 424.0
HFD2_k127_4888945_20 Protein of unknown function DUF72 - - - 0.0000002499 53.0
HFD2_k127_4888945_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 358.0
HFD2_k127_4888945_4 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 350.0
HFD2_k127_4888945_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
HFD2_k127_4888945_6 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 337.0
HFD2_k127_4888945_7 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009516 276.0
HFD2_k127_4888945_8 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
HFD2_k127_4888945_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001248 252.0
HFD2_k127_4893229_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 6.568e-228 713.0
HFD2_k127_4893229_1 - - - - 0.00000000000000000000000002757 118.0
HFD2_k127_4894258_0 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 363.0
HFD2_k127_4894258_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000001354 174.0
HFD2_k127_4894625_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 462.0
HFD2_k127_4894625_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 316.0
HFD2_k127_4894625_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 302.0
HFD2_k127_4894625_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000005077 162.0
HFD2_k127_4894625_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000002964 143.0
HFD2_k127_4894625_5 cytochrome C K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.00000000000000009801 90.0
HFD2_k127_491745_0 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 304.0
HFD2_k127_491745_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000003465 102.0
HFD2_k127_491745_2 PFAM Flavin containing amine oxidoreductase - - - 0.0000000000003194 72.0
HFD2_k127_4940337_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 361.0
HFD2_k127_4940337_1 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000001151 177.0
HFD2_k127_4940337_2 - - - - 0.00000000000000000000000000000000000000003082 172.0
HFD2_k127_4940337_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000001187 71.0
HFD2_k127_4963411_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
HFD2_k127_4963411_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 349.0
HFD2_k127_4963411_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000936 264.0
HFD2_k127_4963411_3 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000002605 153.0
HFD2_k127_4987711_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 602.0
HFD2_k127_4987711_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000007632 116.0
HFD2_k127_4997017_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.617e-313 980.0
HFD2_k127_4997017_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.813e-280 882.0
HFD2_k127_4997017_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 334.0
HFD2_k127_4997017_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000003201 121.0
HFD2_k127_5002375_0 alpha beta alpha domain I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 337.0
HFD2_k127_5002375_1 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 327.0
HFD2_k127_5002375_2 TIGRFAM mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000001468 225.0
HFD2_k127_5022672_0 Tricorn protease homolog - - - 5.617e-302 950.0
HFD2_k127_5024571_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 353.0
HFD2_k127_5024571_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 300.0
HFD2_k127_5024571_2 DinB superfamily K07552 - - 0.000000000000000000000000000000000000002928 151.0
HFD2_k127_5070095_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 544.0
HFD2_k127_5070095_1 MafB19-like deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000004655 226.0
HFD2_k127_5070095_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000001996 175.0
HFD2_k127_5081939_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 474.0
HFD2_k127_5081939_1 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000006925 212.0
HFD2_k127_5081939_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000001048 124.0
HFD2_k127_5081939_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000001339 92.0
HFD2_k127_5081939_4 Barstar (barnase inhibitor) - - - 0.000000000002311 73.0
HFD2_k127_5090595_0 Carboxyl transferase domain - - - 2.393e-264 825.0
HFD2_k127_5090595_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 597.0
HFD2_k127_5090595_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 317.0
HFD2_k127_5090595_3 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
HFD2_k127_5090595_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
HFD2_k127_5094049_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
HFD2_k127_5094049_1 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000004001 211.0
HFD2_k127_5094049_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000001536 145.0
HFD2_k127_5094049_3 - - - - 0.00000000000000000000000003558 116.0
HFD2_k127_5094049_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000004715 78.0
HFD2_k127_5094049_5 Putative zinc-finger - - - 0.00000000000003987 80.0
HFD2_k127_5111428_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1274.0
HFD2_k127_5159375_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 422.0
HFD2_k127_5159375_1 Glycosyl transferases group 1 - - - 0.00000000003407 70.0
HFD2_k127_5168845_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 6.819e-194 631.0
HFD2_k127_5168845_1 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 416.0
HFD2_k127_5168845_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 381.0
HFD2_k127_5168845_3 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 374.0
HFD2_k127_5168845_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 334.0
HFD2_k127_5168845_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 307.0
HFD2_k127_5168845_6 Nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000000000036 219.0
HFD2_k127_5168845_7 SnoaL-like domain - - - 0.000000000000000000000000004773 116.0
HFD2_k127_5168845_8 Regulatory protein, FmdB - - - 0.0000000000000000000005427 98.0
HFD2_k127_5168845_9 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000666 99.0
HFD2_k127_5187704_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 394.0
HFD2_k127_518876_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 478.0
HFD2_k127_518876_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 359.0
HFD2_k127_518876_10 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000006104 103.0
HFD2_k127_518876_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000006769 85.0
HFD2_k127_518876_12 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.00000000000000005273 89.0
HFD2_k127_518876_2 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000528 226.0
HFD2_k127_518876_3 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000004372 191.0
HFD2_k127_518876_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000004195 183.0
HFD2_k127_518876_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000003567 181.0
HFD2_k127_518876_6 PAP2 superfamily - - - 0.000000000000000000000000000000000000000001191 171.0
HFD2_k127_518876_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000008296 146.0
HFD2_k127_518876_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000001224 135.0
HFD2_k127_518876_9 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000005299 119.0
HFD2_k127_5199180_0 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 415.0
HFD2_k127_5199180_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 309.0
HFD2_k127_5199180_2 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
HFD2_k127_5199180_3 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000000000000000000000000000002063 199.0
HFD2_k127_5199180_5 Rhomboid family - - - 0.0000000000000000000000000001392 128.0
HFD2_k127_5224333_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 364.0
HFD2_k127_5224333_1 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000005093 219.0
HFD2_k127_5224333_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000004397 166.0
HFD2_k127_5224333_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000001434 152.0
HFD2_k127_5226179_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 432.0
HFD2_k127_5226179_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
HFD2_k127_5226179_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
HFD2_k127_5226179_3 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000001255 122.0
HFD2_k127_5226179_4 protein conserved in bacteria K04750 - - 0.00000000000000000000001696 107.0
HFD2_k127_5226179_5 - - - - 0.00000000000000001897 86.0
HFD2_k127_5255865_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.098e-280 888.0
HFD2_k127_5255865_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 598.0
HFD2_k127_5255865_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 537.0
HFD2_k127_5255865_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 409.0
HFD2_k127_5255865_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
HFD2_k127_5255865_5 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000002978 233.0
HFD2_k127_5255865_6 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000005629 219.0
HFD2_k127_5255865_7 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000008864 154.0
HFD2_k127_5255865_8 Modulates RecA activity K03565 - - 0.0000000000000002356 85.0
HFD2_k127_5255865_9 - - - - 0.0002845 49.0
HFD2_k127_5281663_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 633.0
HFD2_k127_5281663_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 386.0
HFD2_k127_5281663_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000005182 177.0
HFD2_k127_5281663_3 - - - - 0.0000000000000000000000000000000000000000002362 162.0
HFD2_k127_5298806_0 Ftsk_gamma K03466 - - 2.747e-244 776.0
HFD2_k127_5298806_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 349.0
HFD2_k127_5298806_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000005546 194.0
HFD2_k127_5298806_3 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000000157 124.0
HFD2_k127_5298806_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000000228 123.0
HFD2_k127_5298806_5 peptidase inhibitor activity - - - 0.00000000000000000000000001591 121.0
HFD2_k127_5298806_6 ACT domain - - - 0.000000000000004009 80.0
HFD2_k127_5298806_7 - - - - 0.00000000002301 69.0
HFD2_k127_5299631_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 304.0
HFD2_k127_5299631_1 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000003112 169.0
HFD2_k127_532640_0 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 292.0
HFD2_k127_532640_1 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000006573 230.0
HFD2_k127_532640_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000002524 132.0
HFD2_k127_532640_3 Enoyl-CoA hydratase/isomerase - - - 0.000000002783 60.0
HFD2_k127_5359337_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000005297 209.0
HFD2_k127_5359337_1 - - - - 0.000000000000000000000000000000000000000000000000000186 195.0
HFD2_k127_5359337_2 - - - - 0.00000001056 61.0
HFD2_k127_5359337_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0002251 51.0
HFD2_k127_5382371_0 Dienelactone hydrolase family - - - 9.721e-283 883.0
HFD2_k127_5382371_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.076e-201 637.0
HFD2_k127_5382371_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 587.0
HFD2_k127_5382371_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 522.0
HFD2_k127_5391053_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 567.0
HFD2_k127_5391053_1 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 368.0
HFD2_k127_5391053_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
HFD2_k127_5391053_3 methyltransferase - - - 0.0000000000000000000000000008415 122.0
HFD2_k127_5391053_4 PilZ domain - - - 0.00006841 50.0
HFD2_k127_5391077_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 563.0
HFD2_k127_5391077_1 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 482.0
HFD2_k127_5391077_10 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000008588 177.0
HFD2_k127_5391077_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 392.0
HFD2_k127_5391077_3 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
HFD2_k127_5391077_4 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 363.0
HFD2_k127_5391077_5 PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 344.0
HFD2_k127_5391077_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
HFD2_k127_5391077_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000006345 193.0
HFD2_k127_5391077_8 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000007498 184.0
HFD2_k127_5391077_9 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000001284 184.0
HFD2_k127_5401457_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 515.0
HFD2_k127_5401457_1 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 305.0
HFD2_k127_5401457_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
HFD2_k127_5420864_0 dihydroorotate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 477.0
HFD2_k127_5420864_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000005577 196.0
HFD2_k127_5422622_0 Carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 458.0
HFD2_k127_5422622_1 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000001168 98.0
HFD2_k127_5450675_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 2.222e-273 859.0
HFD2_k127_5450675_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.094e-244 769.0
HFD2_k127_5450675_10 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000000000000000001134 181.0
HFD2_k127_5450675_11 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000003325 142.0
HFD2_k127_5450675_13 virulence factor MVIN family protein - - - 0.000000000000000000000000001283 128.0
HFD2_k127_5450675_14 DNA-templated transcription, initiation K03088 - - 0.0000000000006423 74.0
HFD2_k127_5450675_15 - - - - 0.00000002527 63.0
HFD2_k127_5450675_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 510.0
HFD2_k127_5450675_3 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 432.0
HFD2_k127_5450675_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 378.0
HFD2_k127_5450675_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 364.0
HFD2_k127_5450675_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 302.0
HFD2_k127_5450675_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 275.0
HFD2_k127_5450675_8 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 271.0
HFD2_k127_5450675_9 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000001756 214.0
HFD2_k127_5451457_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 7.34e-206 653.0
HFD2_k127_5451457_1 amino acid K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 394.0
HFD2_k127_5451457_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007569 270.0
HFD2_k127_5451457_3 STAS domain - - - 0.000001114 55.0
HFD2_k127_5451457_4 homocysteine K00297,K00547 GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 0.000004886 48.0
HFD2_k127_549042_0 Glycosyl hydrolase family 47 K01230,K10085 - 3.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 546.0
HFD2_k127_549042_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000005654 171.0
HFD2_k127_549042_2 Tetratricopeptide repeat - - - 0.0000000000000000000001418 112.0
HFD2_k127_549042_3 Putative zinc-finger - - - 0.00000000000001168 78.0
HFD2_k127_550441_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.817e-224 705.0
HFD2_k127_550441_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000009614 222.0
HFD2_k127_5508750_0 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 534.0
HFD2_k127_5508750_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 334.0
HFD2_k127_5508750_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 281.0
HFD2_k127_5508750_4 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
HFD2_k127_5517637_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 460.0
HFD2_k127_5525538_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 533.0
HFD2_k127_5525538_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 398.0
HFD2_k127_5525538_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000003541 159.0
HFD2_k127_5525538_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000005849 93.0
HFD2_k127_5533359_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 310.0
HFD2_k127_5533359_1 - K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
HFD2_k127_5533359_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000004854 169.0
HFD2_k127_5564171_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 471.0
HFD2_k127_5564171_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000001542 213.0
HFD2_k127_5564171_2 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000005062 174.0
HFD2_k127_5564489_0 MacB-like periplasmic core domain - - - 8.17e-272 861.0
HFD2_k127_5564489_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 613.0
HFD2_k127_5564489_2 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 600.0
HFD2_k127_5564489_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 552.0
HFD2_k127_5564489_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 531.0
HFD2_k127_5564489_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 519.0
HFD2_k127_5564489_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005381 281.0
HFD2_k127_5564489_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000006036 222.0
HFD2_k127_5564489_8 Recombinase - - - 0.000000000000000000000000000000000006774 141.0
HFD2_k127_5564489_9 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000003967 73.0
HFD2_k127_5569219_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 515.0
HFD2_k127_5569219_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
HFD2_k127_5569219_2 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002521 220.0
HFD2_k127_5569219_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000001804 161.0
HFD2_k127_5569538_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 618.0
HFD2_k127_5569538_1 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000006194 204.0
HFD2_k127_5574966_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 459.0
HFD2_k127_5574966_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 426.0
HFD2_k127_5574966_2 protein conserved in bacteria K09931 - - 0.0000000000000000000000000002289 123.0
HFD2_k127_5574966_3 YtxH-like protein - - - 0.0000000000000000004198 89.0
HFD2_k127_5574966_4 - - - - 0.00000000000003289 79.0
HFD2_k127_5590361_0 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 338.0
HFD2_k127_5590361_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002059 255.0
HFD2_k127_5590361_2 - - - - 0.00000000000000000000000000000000000000000000000000000000007793 216.0
HFD2_k127_5590361_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000001007 170.0
HFD2_k127_5590361_4 Polysulphide reductase, NrfD K00185 - - 0.00000000000002871 76.0
HFD2_k127_5590361_5 nitrous-oxide reductase activity - - - 0.0000000708 60.0
HFD2_k127_5590361_6 cytochrome - - - 0.0008573 46.0
HFD2_k127_5598227_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.497e-249 791.0
HFD2_k127_5598227_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002362 275.0
HFD2_k127_5598227_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 250.0
HFD2_k127_5598227_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000006735 232.0
HFD2_k127_5598227_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000004456 143.0
HFD2_k127_5598227_5 methylamine metabolic process - - - 0.0000000000000000000000007707 111.0
HFD2_k127_5598227_6 - - - - 0.0000009605 60.0
HFD2_k127_5598227_7 - - - - 0.00014 47.0
HFD2_k127_5602076_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 529.0
HFD2_k127_5602076_1 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000001092 191.0
HFD2_k127_5602076_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000002821 134.0
HFD2_k127_5602076_3 Predicted membrane protein (DUF2231) - - - 0.00000000000000008444 86.0
HFD2_k127_5602076_4 Cysteine-rich CWC - - - 0.0000000004175 64.0
HFD2_k127_5602076_6 - - - - 0.0003713 50.0
HFD2_k127_5610649_0 cellulose binding - - - 0.0 1334.0
HFD2_k127_5610649_1 AcrB/AcrD/AcrF family - - - 9.034e-313 990.0
HFD2_k127_5610649_2 serine-type peptidase activity K01303 - 3.4.19.1 2.77e-306 952.0
HFD2_k127_5610649_3 transmembrane transporter activity K08196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 595.0
HFD2_k127_5610649_4 glutamate-1-semialdehyde 2,1-aminomutase activity K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 481.0
HFD2_k127_5610649_5 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 377.0
HFD2_k127_5610649_6 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 357.0
HFD2_k127_5610649_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000001026 237.0
HFD2_k127_5610649_8 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000001203 211.0
HFD2_k127_5610649_9 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000002893 145.0
HFD2_k127_561168_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 526.0
HFD2_k127_561168_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 428.0
HFD2_k127_561168_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000004882 179.0
HFD2_k127_561168_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000008119 171.0
HFD2_k127_561168_4 - - - - 0.00000000000000000000061 107.0
HFD2_k127_561168_5 Domain of unknown function (DUF4115) - - - 0.0000000000000002049 88.0
HFD2_k127_5658280_0 Beta-galactosidase K12308 - 3.2.1.23 0.0000000000000000000000000004562 134.0
HFD2_k127_5658280_1 COG1254 Acylphosphatases K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000001969 66.0
HFD2_k127_5672382_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 504.0
HFD2_k127_5672382_1 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000009338 189.0
HFD2_k127_5672382_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000001237 172.0
HFD2_k127_5672382_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000006174 104.0
HFD2_k127_5672382_4 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000001011 102.0
HFD2_k127_5672382_5 Belongs to the GSP D family K02453 - - 0.00000263 54.0
HFD2_k127_5689881_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 464.0
HFD2_k127_5689881_1 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
HFD2_k127_5689881_10 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.0005401 43.0
HFD2_k127_5689881_2 photosynthesis - - - 0.000000000000000000000000000000000000000000000000003204 187.0
HFD2_k127_5689881_3 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000002641 173.0
HFD2_k127_5689881_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000002872 174.0
HFD2_k127_5689881_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000158 164.0
HFD2_k127_5689881_6 Thioredoxin - - - 0.00000000000000000000000000000000000000008248 162.0
HFD2_k127_5689881_7 methyltransferase - - - 0.00000000000000000000000000000000003146 142.0
HFD2_k127_5689881_8 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.00000000000000001493 84.0
HFD2_k127_5689881_9 - - - - 0.000000000001903 76.0
HFD2_k127_5719082_0 Transketolase b K00615 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031935,GO:0033043,GO:0033044,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0060968,GO:0065007,GO:0080090,GO:1902275,GO:1903506,GO:2000112,GO:2001141 2.2.1.1 1.337e-198 638.0
HFD2_k127_5719082_1 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 599.0
HFD2_k127_5719082_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 415.0
HFD2_k127_5719082_3 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 373.0
HFD2_k127_5719082_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 336.0
HFD2_k127_5719082_5 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 301.0
HFD2_k127_5719082_6 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002903 265.0
HFD2_k127_5719082_7 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000006252 192.0
HFD2_k127_5719082_8 shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000003219 141.0
HFD2_k127_5747436_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000005397 199.0
HFD2_k127_5747436_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000001577 181.0
HFD2_k127_5747436_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000006154 80.0
HFD2_k127_5747436_3 Protein of unknown function (DUF465) - - - 0.000002829 53.0
HFD2_k127_5750744_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 321.0
HFD2_k127_5750744_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000736 192.0
HFD2_k127_5750744_2 deoxyhypusine monooxygenase activity K02288 - 4.4.1.32 0.000001031 59.0
HFD2_k127_5760683_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.393e-235 734.0
HFD2_k127_5760683_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 404.0
HFD2_k127_5760683_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 357.0
HFD2_k127_5760683_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009204 273.0
HFD2_k127_5762913_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1298.0
HFD2_k127_5762913_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 419.0
HFD2_k127_5762913_10 TonB dependent receptor K16087 - - 0.00000000000000000000000000000001941 145.0
HFD2_k127_5762913_11 TonB dependent receptor - - - 0.00000000000000000000000009766 124.0
HFD2_k127_5762913_12 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.0000000000000000000000003194 110.0
HFD2_k127_5762913_13 PFAM Abortive infection protein K07052 - - 0.00000000000000000000005199 109.0
HFD2_k127_5762913_14 Protein of unknown function (DUF2892) - - - 0.000000000000000000001022 97.0
HFD2_k127_5762913_15 Penicillinase repressor - - - 0.0000000000000000001225 95.0
HFD2_k127_5762913_16 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000003831 81.0
HFD2_k127_5762913_17 metalloendopeptidase activity K03799 - - 0.0000009865 61.0
HFD2_k127_5762913_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 411.0
HFD2_k127_5762913_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 378.0
HFD2_k127_5762913_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001021 291.0
HFD2_k127_5762913_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003092 238.0
HFD2_k127_5762913_6 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000001608 204.0
HFD2_k127_5762913_7 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000001581 153.0
HFD2_k127_5762913_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000005989 147.0
HFD2_k127_5762913_9 DinB superfamily - - - 0.00000000000000000000000000000000000005684 151.0
HFD2_k127_5821940_0 Oligopeptide transporter OPT - - - 1.401e-273 860.0
HFD2_k127_5821940_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 568.0
HFD2_k127_5821940_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 504.0
HFD2_k127_5821940_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 492.0
HFD2_k127_5821940_4 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
HFD2_k127_5821940_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 302.0
HFD2_k127_5821940_6 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 293.0
HFD2_k127_5821940_7 Rhomboid family - - - 0.000000000000000000000000000000000000000000000008928 181.0
HFD2_k127_5838223_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001472 245.0
HFD2_k127_5841842_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000003385 211.0
HFD2_k127_5841842_1 DinB family - - - 0.00000000000000000000000000000000000000000000000000000004391 201.0
HFD2_k127_5841842_2 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000000000000000000000000000000000009803 160.0
HFD2_k127_5841842_3 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000003761 150.0
HFD2_k127_5841842_4 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000001753 64.0
HFD2_k127_5856133_0 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 502.0
HFD2_k127_5856133_1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 329.0
HFD2_k127_5896798_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.484e-228 715.0
HFD2_k127_5896798_1 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000006691 138.0
HFD2_k127_5896798_2 Calcineurin-like phosphoesterase K07098 - - 0.000000000000002905 77.0
HFD2_k127_5908165_0 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002111 254.0
HFD2_k127_5908165_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
HFD2_k127_5908165_2 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000003987 139.0
HFD2_k127_5908165_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000001077 80.0
HFD2_k127_5908304_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
HFD2_k127_5908304_1 - - - - 0.000000000000000000000000000000000000000000001374 173.0
HFD2_k127_5908304_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000131 141.0
HFD2_k127_5908304_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000017 50.0
HFD2_k127_5929501_0 Peptidase S46 - - - 2.828e-262 826.0
HFD2_k127_5929501_1 Prolyl oligopeptidase family - - - 2.682e-218 700.0
HFD2_k127_5929501_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000003256 189.0
HFD2_k127_5929501_3 von Willebrand factor, type A K07114 - - 0.000000006092 68.0
HFD2_k127_5948108_0 PFAM Cytochrome c assembly protein K02198 - - 4.021e-240 760.0
HFD2_k127_5948108_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
HFD2_k127_5948108_2 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 300.0
HFD2_k127_5948108_3 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000005743 230.0
HFD2_k127_5948108_4 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
HFD2_k127_5948108_5 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000001797 180.0
HFD2_k127_5948108_6 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000001282 174.0
HFD2_k127_5948108_7 - - - - 0.00000000000000000000000002019 123.0
HFD2_k127_5948108_8 subunit of a heme lyase K02200 - - 0.0000000000000000000000327 106.0
HFD2_k127_5948108_9 - - - - 0.00000000000000002871 88.0
HFD2_k127_597233_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 484.0
HFD2_k127_597233_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 323.0
HFD2_k127_597233_2 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 289.0
HFD2_k127_597233_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003743 276.0
HFD2_k127_597233_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000001464 240.0
HFD2_k127_597233_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000001748 230.0
HFD2_k127_597233_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000003225 123.0
HFD2_k127_598989_0 - K21449 - - 0.0000000000000004331 92.0
HFD2_k127_598989_1 - - - - 0.000000000007206 79.0
HFD2_k127_598989_3 tail collar domain protein - - - 0.000006823 60.0
HFD2_k127_5990532_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.483e-219 704.0
HFD2_k127_5990532_1 PFAM Glycosyl transferase family 2 - - - 2.139e-214 678.0
HFD2_k127_5990532_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000004932 150.0
HFD2_k127_5990532_3 Cupin domain - - - 0.00000000000000000000000000000000000005833 145.0
HFD2_k127_5990532_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000121 152.0
HFD2_k127_5990532_5 alkyl hydroperoxide reductase - - - 0.0000000000000000000000000000002749 130.0
HFD2_k127_5990532_6 Heavy-metal resistance - - - 0.0000000000000000000005189 104.0
HFD2_k127_6017313_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 537.0
HFD2_k127_6017313_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 443.0
HFD2_k127_602361_0 Domain of unknown function (DUF4139) - - - 4.091e-211 682.0
HFD2_k127_602361_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 389.0
HFD2_k127_602361_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000773 60.0
HFD2_k127_6040466_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 432.0
HFD2_k127_6040466_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005501 272.0
HFD2_k127_6040466_2 YbbR-like protein - - - 0.00000000001505 69.0
HFD2_k127_6040466_3 peroxiredoxin activity - - - 0.00002357 53.0
HFD2_k127_6040466_4 - - - - 0.0001415 48.0
HFD2_k127_6047470_0 methyltransferase - - - 0.0000000000000000000000001349 115.0
HFD2_k127_6047470_1 DUF218 domain - - - 0.00000000000000009689 89.0
HFD2_k127_6047470_2 Polymer-forming cytoskeletal - - - 0.00000000000001213 81.0
HFD2_k127_6047470_3 ATP-independent chaperone mediated protein folding K06006,K07803 - - 0.0000001432 59.0
HFD2_k127_6071253_0 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 529.0
HFD2_k127_6071253_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 298.0
HFD2_k127_6071253_2 Isopropylmalate homocitrate citramalate synthase K01640 - 4.1.3.4 0.00000418 49.0
HFD2_k127_6072176_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.886e-214 683.0
HFD2_k127_6072176_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 435.0
HFD2_k127_6072176_2 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 335.0
HFD2_k127_6072176_3 CYTH K05873 - 4.6.1.1 0.0000000000000000002135 99.0
HFD2_k127_6075764_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 356.0
HFD2_k127_6075764_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000008363 159.0
HFD2_k127_6077259_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.833e-241 754.0
HFD2_k127_6077259_1 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 4.064e-208 656.0
HFD2_k127_6077259_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 452.0
HFD2_k127_6077259_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 450.0
HFD2_k127_6077259_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 291.0
HFD2_k127_6077259_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003193 266.0
HFD2_k127_6077259_6 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000001789 202.0
HFD2_k127_6077259_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000000001527 132.0
HFD2_k127_6077259_8 Peptidoglycan-binding domain 1 protein K01185,K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.17,3.5.1.28 0.000000000008715 74.0
HFD2_k127_6077259_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0002177 44.0
HFD2_k127_6093545_0 cellulose binding - - - 0.0 1197.0
HFD2_k127_6093545_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 531.0
HFD2_k127_6093545_10 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000002666 131.0
HFD2_k127_6093545_11 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000001489 115.0
HFD2_k127_6093545_2 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 440.0
HFD2_k127_6093545_3 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 381.0
HFD2_k127_6093545_4 Aminotransferase class-V K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 340.0
HFD2_k127_6093545_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002636 248.0
HFD2_k127_6093545_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002922 252.0
HFD2_k127_6093545_7 Nitroreductase family - - - 0.000000000000000000000000000000000000000000005391 177.0
HFD2_k127_6093545_8 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000002346 141.0
HFD2_k127_6093545_9 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000004009 142.0
HFD2_k127_6101640_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 537.0
HFD2_k127_6101640_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 327.0
HFD2_k127_6101640_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000006941 202.0
HFD2_k127_6101640_3 AIR carboxylase K06898 - - 0.0000000000000000000000000001428 118.0
HFD2_k127_611827_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.667e-295 922.0
HFD2_k127_6159379_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 329.0
HFD2_k127_6159379_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000885 201.0
HFD2_k127_6159379_2 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000006157 138.0
HFD2_k127_6159379_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0001089 49.0
HFD2_k127_6167479_0 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 554.0
HFD2_k127_6167479_1 - - - - 0.0000000000000000000000000000000000000000000000000000000008409 217.0
HFD2_k127_6167479_2 O-linked N-acetylglucosamine transferase - - - 0.0000001445 63.0
HFD2_k127_6173230_0 Cytochrome c554 and c-prime - - - 4.431e-241 758.0
HFD2_k127_6173230_1 ASPIC and UnbV - - - 3.158e-211 667.0
HFD2_k127_6173230_2 - - - - 0.0000000000000000000000000000000000000007227 152.0
HFD2_k127_6173230_3 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000003804 121.0
HFD2_k127_6205493_0 aminopeptidase - - - 9.709e-202 644.0
HFD2_k127_6205493_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 451.0
HFD2_k127_6205493_2 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 347.0
HFD2_k127_6205493_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000000000000000278 179.0
HFD2_k127_6205493_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000000226 143.0
HFD2_k127_6205493_5 Cupin domain - - - 0.000000000000000000000000002473 114.0
HFD2_k127_6205493_6 Cold shock protein domain K03704 - - 0.00000000000000000000000002365 110.0
HFD2_k127_6205493_7 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000001622 106.0
HFD2_k127_6205493_8 GYD domain - - - 0.000000000000000002036 85.0
HFD2_k127_6220644_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 439.0
HFD2_k127_6220644_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
HFD2_k127_6220644_2 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000000000000000000002325 206.0
HFD2_k127_6220644_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000001498 178.0
HFD2_k127_6220644_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001634 127.0
HFD2_k127_6220644_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0002316 45.0
HFD2_k127_6223716_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 5.645e-198 632.0
HFD2_k127_6223716_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 430.0
HFD2_k127_6243401_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 471.0
HFD2_k127_6243401_1 ferredoxin-NADP+ reductase activity K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 395.0
HFD2_k127_6243401_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000007843 216.0
HFD2_k127_6243401_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000276 150.0
HFD2_k127_6243401_4 DinB superfamily K07552 - - 0.000000000000000000000000000001272 128.0
HFD2_k127_6243401_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000009907 97.0
HFD2_k127_6243401_6 TIGRFAM DMSO reductase family type II enzyme, heme b subunit K17052 - - 0.000000000000001596 85.0
HFD2_k127_6243401_7 Nitrate reductase delta subunit - - - 0.0000001445 61.0
HFD2_k127_6243401_8 - - - - 0.0006268 50.0
HFD2_k127_6251206_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 3.101e-210 674.0
HFD2_k127_6251206_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 486.0
HFD2_k127_6251206_2 Participates in the control of copper homeostasis K06201 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003116 274.0
HFD2_k127_6251206_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000812 214.0
HFD2_k127_6251206_4 - - - - 0.00000000000000000000000000000000000000000000000000000001889 205.0
HFD2_k127_6251206_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000005555 197.0
HFD2_k127_6251680_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1047.0
HFD2_k127_6251680_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000002626 98.0
HFD2_k127_6255396_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 308.0
HFD2_k127_6255396_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000008188 135.0
HFD2_k127_6255396_2 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000004446 106.0
HFD2_k127_6261505_0 carboxylic ester hydrolase activity K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
HFD2_k127_6261505_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000001519 270.0
HFD2_k127_6261505_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002947 245.0
HFD2_k127_6261505_3 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
HFD2_k127_6261505_4 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000004078 135.0
HFD2_k127_6261505_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000001207 145.0
HFD2_k127_6261505_6 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000000003952 122.0
HFD2_k127_6261505_7 Forkhead associated domain K03466 - - 0.000000000000009874 79.0
HFD2_k127_6261505_8 Methyltransferase domain - - - 0.00001537 56.0
HFD2_k127_6264361_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 361.0
HFD2_k127_6264361_1 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 313.0
HFD2_k127_6264361_10 hydrolase, subfamily IA, variant 3 K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000000008316 59.0
HFD2_k127_6264361_2 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
HFD2_k127_6264361_3 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000004528 158.0
HFD2_k127_6264361_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000008015 153.0
HFD2_k127_6264361_5 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.00000000000000000000000000000174 128.0
HFD2_k127_6264361_6 Winged helix DNA-binding domain - - - 0.0000000000000000000000000007069 119.0
HFD2_k127_6264361_7 - - - - 0.000000000000000000000000001659 121.0
HFD2_k127_6264361_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000143 110.0
HFD2_k127_6268376_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000434 214.0
HFD2_k127_6268376_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000001122 146.0
HFD2_k127_6268376_2 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000008125 146.0
HFD2_k127_6268376_3 Transmembrane secretion effector - - - 0.00000000000000000000000004317 111.0
HFD2_k127_6268376_4 RESPONSE REGULATOR receiver - - - 0.000007815 54.0
HFD2_k127_6279623_0 Histidine kinase - - - 1.499e-275 872.0
HFD2_k127_6279623_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 580.0
HFD2_k127_6286470_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 421.0
HFD2_k127_6286470_1 PFAM Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000225 271.0
HFD2_k127_6286470_2 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000001759 144.0
HFD2_k127_6289731_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 591.0
HFD2_k127_6289731_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 434.0
HFD2_k127_6289731_2 ABC-2 family transporter protein - - - 0.00000000185 63.0
HFD2_k127_6293161_0 serine threonine protein kinase K12132 - 2.7.11.1 2.419e-221 715.0
HFD2_k127_6293161_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 520.0
HFD2_k127_6293161_10 domain protein - - - 0.000001134 63.0
HFD2_k127_6293161_12 Metallo-peptidase family M12B Reprolysin-like - - - 0.00004051 58.0
HFD2_k127_6293161_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 499.0
HFD2_k127_6293161_3 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 309.0
HFD2_k127_6293161_4 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001085 222.0
HFD2_k127_6293161_5 serine-type peptidase activity K01278,K06889 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000001927 198.0
HFD2_k127_6293161_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000003784 181.0
HFD2_k127_6293161_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000007965 155.0
HFD2_k127_6293161_8 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000002598 134.0
HFD2_k127_6293161_9 PFAM UspA domain protein K06149 - - 0.000000000000000000000306 102.0
HFD2_k127_6309614_0 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 302.0
HFD2_k127_6309614_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 284.0
HFD2_k127_6309614_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000001764 199.0
HFD2_k127_6309614_3 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000006684 181.0
HFD2_k127_6309614_4 Haloacid dehalogenase-like hydrolase K11777 - - 0.0000000000000000000000000000000000000008212 160.0
HFD2_k127_6315298_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 462.0
HFD2_k127_6315298_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
HFD2_k127_6315298_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007438 257.0
HFD2_k127_6315298_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000003681 200.0
HFD2_k127_6320506_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 462.0
HFD2_k127_6320506_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
HFD2_k127_6320506_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000003881 219.0
HFD2_k127_6320506_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000005488 216.0
HFD2_k127_6320506_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000002024 141.0
HFD2_k127_6328515_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 6.736e-259 826.0
HFD2_k127_6328515_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000008874 66.0
HFD2_k127_6335488_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 432.0
HFD2_k127_6335488_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 309.0
HFD2_k127_6335488_2 DNA-templated transcription, initiation K03088,K07263 - - 0.00000000000000000000003621 103.0
HFD2_k127_6365884_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 541.0
HFD2_k127_6365884_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000005987 214.0
HFD2_k127_6365884_2 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000002034 71.0
HFD2_k127_6366558_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 569.0
HFD2_k127_6366558_1 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
HFD2_k127_6366558_10 AhpC/TSA antioxidant enzyme - - - 0.00000000001873 69.0
HFD2_k127_6366558_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 335.0
HFD2_k127_6366558_3 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
HFD2_k127_6366558_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
HFD2_k127_6366558_5 ComF family K02242 - - 0.00000000000000000000000000000000002044 146.0
HFD2_k127_6366558_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000004445 137.0
HFD2_k127_6366558_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000002593 117.0
HFD2_k127_6366558_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000001217 89.0
HFD2_k127_6366558_9 Protein of unknown function (DUF2393) - - - 0.0000000000000004524 85.0
HFD2_k127_6374280_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 439.0
HFD2_k127_6374280_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
HFD2_k127_6374280_2 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000005482 104.0
HFD2_k127_6374280_3 TIGRFAM TonB family K03832 - - 0.00000000003994 77.0
HFD2_k127_637757_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1527.0
HFD2_k127_637757_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 293.0
HFD2_k127_637757_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004329 276.0
HFD2_k127_637757_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000002816 212.0
HFD2_k127_637757_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001561 188.0
HFD2_k127_637757_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000006615 178.0
HFD2_k127_637757_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000008433 157.0
HFD2_k127_637757_7 Ribosomal protein L33 K02913 - - 0.0000000000000007925 78.0
HFD2_k127_637757_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000002987 63.0
HFD2_k127_6397313_0 PFAM Peptidase M20 K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 528.0
HFD2_k127_6397313_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
HFD2_k127_6397313_2 - - - - 0.0000000000000005609 80.0
HFD2_k127_6397313_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000008733 70.0
HFD2_k127_6432197_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 413.0
HFD2_k127_6432197_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000004215 214.0
HFD2_k127_6432197_2 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000001026 170.0
HFD2_k127_6432197_3 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000006543 121.0
HFD2_k127_6432197_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000004298 87.0
HFD2_k127_6432197_5 DNA polymerase III, delta' K02340 - 2.7.7.7 0.00000000004391 74.0
HFD2_k127_6434048_0 haloacid dehalogenase-like hydrolase K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000001363 236.0
HFD2_k127_6434048_1 transmembrane transport - - - 0.0000000000000000000001528 106.0
HFD2_k127_649348_0 Protein of unknown function (DUF962) - - - 0.0000000000000000007532 91.0
HFD2_k127_649348_1 ABC transporter transmembrane K18889 - - 0.0000000003456 68.0
HFD2_k127_649348_2 - - - - 0.000005072 56.0
HFD2_k127_6519457_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 578.0
HFD2_k127_6519457_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 486.0
HFD2_k127_6519457_2 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
HFD2_k127_6519457_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057,K02564 - 3.1.1.31,3.5.99.6 0.0000000000257 69.0
HFD2_k127_6531052_0 Carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 354.0
HFD2_k127_6531052_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001471 250.0
HFD2_k127_6531052_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000127 159.0
HFD2_k127_6531052_3 - - - - 0.0000000000000000000000000000001069 133.0
HFD2_k127_6532859_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 514.0
HFD2_k127_6532859_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000009981 176.0
HFD2_k127_6532859_2 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000001107 138.0
HFD2_k127_6532859_3 CHAT domain - - - 0.000000000000000000000000000000000744 136.0
HFD2_k127_6532859_4 PFAM FRG domain - - - 0.0000000000000000000000387 104.0
HFD2_k127_6549984_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 513.0
HFD2_k127_6549984_1 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 485.0
HFD2_k127_6549984_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000002321 231.0
HFD2_k127_6549984_3 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
HFD2_k127_6568885_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000002876 167.0
HFD2_k127_6568885_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000004232 123.0
HFD2_k127_6572284_0 xanthine dehydrogenase activity K07303 - 1.3.99.16 3.943e-289 905.0
HFD2_k127_6572284_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 575.0
HFD2_k127_6572284_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302,K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000004556 245.0
HFD2_k127_6572284_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
HFD2_k127_6572284_4 - - - - 0.000000000000000000000000000000000000000000000000000002421 204.0
HFD2_k127_6572284_5 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000002675 170.0
HFD2_k127_6572284_6 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000005488 159.0
HFD2_k127_6572284_7 - - - - 0.000000000000000001587 90.0
HFD2_k127_6635832_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 400.0
HFD2_k127_6635832_1 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 394.0
HFD2_k127_6635832_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000003022 241.0
HFD2_k127_6635832_3 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000002177 165.0
HFD2_k127_6635832_4 PFAM VanZ - - - 0.000000000000001524 84.0
HFD2_k127_6678583_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 338.0
HFD2_k127_6678583_1 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003702 264.0
HFD2_k127_6678583_2 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000001817 158.0
HFD2_k127_6697875_0 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000009688 179.0
HFD2_k127_6697875_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000006943 179.0
HFD2_k127_6697875_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000009184 178.0
HFD2_k127_6701056_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 261.0
HFD2_k127_6701056_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000005847 186.0
HFD2_k127_6701056_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000004616 76.0
HFD2_k127_6708560_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 267.0
HFD2_k127_6708560_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000507 190.0
HFD2_k127_6708560_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000002846 152.0
HFD2_k127_6708560_3 Haem-binding domain - - - 0.0000000000000000000000000000009402 128.0
HFD2_k127_6728322_0 Iron permease FTR1 family K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000002245 57.0
HFD2_k127_6728322_1 Secretin and TonB N terminus short domain K02453 - - 0.00000007638 64.0
HFD2_k127_6766920_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
HFD2_k127_6766920_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000001571 234.0
HFD2_k127_6766920_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000004469 231.0
HFD2_k127_6766920_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000005288 111.0
HFD2_k127_6766920_4 mttA/Hcf106 family K03116 - - 0.00000000000000000002733 94.0
HFD2_k127_6839343_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 508.0
HFD2_k127_6839343_1 PFAM Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
HFD2_k127_6839343_2 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
HFD2_k127_6839343_3 DoxX - - - 0.0000000000000000000000000000000000000000000000000008932 189.0
HFD2_k127_6839343_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000001918 177.0
HFD2_k127_6839343_5 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000009155 151.0
HFD2_k127_6839343_6 membrane transporter protein - - - 0.0000000000000000000000000002438 123.0
HFD2_k127_6839343_7 Patatin-like phospholipase - - - 0.0000000000000000001198 92.0
HFD2_k127_6839343_8 Bacterial regulatory proteins, tetR family - - - 0.0000000262 63.0
HFD2_k127_6840813_0 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 449.0
HFD2_k127_6840813_1 PFAM ABC transporter related K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 370.0
HFD2_k127_6840813_10 glyoxalase III activity K00799 - 2.5.1.18 0.000000000000000000005792 101.0
HFD2_k127_6840813_11 lipopolysaccharide metabolic process K08309,K19804 - - 0.000000007797 68.0
HFD2_k127_6840813_2 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
HFD2_k127_6840813_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 301.0
HFD2_k127_6840813_4 transcriptional regulator K16137 - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
HFD2_k127_6840813_5 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000003168 211.0
HFD2_k127_6840813_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000009129 154.0
HFD2_k127_6840813_9 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000003113 146.0
HFD2_k127_6846275_0 ankyrin repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 577.0
HFD2_k127_6846275_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 492.0
HFD2_k127_6846275_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 453.0
HFD2_k127_6846275_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 391.0
HFD2_k127_6846275_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001389 164.0
HFD2_k127_6846275_5 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000001072 78.0
HFD2_k127_6846275_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0001053 53.0
HFD2_k127_686809_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003111 278.0
HFD2_k127_686809_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
HFD2_k127_686809_2 Redoxin - - - 0.000000000000000000000000000000000000768 145.0
HFD2_k127_6869050_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 408.0
HFD2_k127_6869050_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000007693 181.0
HFD2_k127_6869050_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000002136 145.0
HFD2_k127_6869050_3 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000003168 111.0
HFD2_k127_6869050_4 - - - - 0.000000000000000003461 96.0
HFD2_k127_6873109_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000006596 170.0
HFD2_k127_6873109_1 peptidoglycan glycosyltransferase activity K03588 - - 0.000000000000000009754 97.0
HFD2_k127_6873109_2 Glycosyltransferase - - - 0.00005876 49.0
HFD2_k127_6875321_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.044e-277 871.0
HFD2_k127_6875321_1 PFAM amidohydrolase K01464 - 3.5.2.2 2.37e-197 625.0
HFD2_k127_6875321_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 394.0
HFD2_k127_6875321_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000003382 76.0
HFD2_k127_6896157_0 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 562.0
HFD2_k127_6896157_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 409.0
HFD2_k127_6896157_2 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 293.0
HFD2_k127_6896157_3 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
HFD2_k127_6896157_4 Histidine kinase - - - 0.00000000000000000000000000000009562 143.0
HFD2_k127_6896157_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000001513 125.0
HFD2_k127_6901026_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.424e-245 771.0
HFD2_k127_6901026_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 1.381e-213 692.0
HFD2_k127_6901026_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000002114 94.0
HFD2_k127_6901026_11 SnoaL-like domain - - - 0.0000000000000009615 83.0
HFD2_k127_6901026_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 468.0
HFD2_k127_6901026_3 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 303.0
HFD2_k127_6901026_4 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007829 289.0
HFD2_k127_6901026_5 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001427 278.0
HFD2_k127_6901026_6 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000004973 236.0
HFD2_k127_6901026_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000002021 167.0
HFD2_k127_6901026_8 diguanylate cyclase - - - 0.0000000000000000000000000000007728 141.0
HFD2_k127_6901026_9 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000526 89.0
HFD2_k127_6901247_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 2.424e-236 750.0
HFD2_k127_6901247_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 597.0
HFD2_k127_6901247_10 Gaf domain K03832 - - 0.0000000001941 74.0
HFD2_k127_6901247_11 Putative adhesin - - - 0.0000000003247 70.0
HFD2_k127_6901247_12 - - - - 0.00001274 58.0
HFD2_k127_6901247_13 MacB-like periplasmic core domain K09808 - - 0.00002283 49.0
HFD2_k127_6901247_14 - - - - 0.0007086 50.0
HFD2_k127_6901247_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
HFD2_k127_6901247_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
HFD2_k127_6901247_4 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000007395 162.0
HFD2_k127_6901247_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000003001 134.0
HFD2_k127_6901247_6 - - - - 0.000000000000000000000000003079 121.0
HFD2_k127_6901247_7 HEAT repeats - - - 0.000000000000000004936 96.0
HFD2_k127_6901247_8 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000006036 77.0
HFD2_k127_6901247_9 Conserved hypothetical protein 95 - - - 0.0000000001891 63.0
HFD2_k127_6965604_0 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 502.0
HFD2_k127_6965604_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 470.0
HFD2_k127_6965604_2 amine dehydrogenase activity - - - 0.00000000000000000000000005581 110.0
HFD2_k127_6965604_3 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.0000000000000001278 90.0
HFD2_k127_6965604_4 F420H(2)-dependent quinone reductase - - - 0.00000000003217 71.0
HFD2_k127_6987618_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 399.0
HFD2_k127_6987618_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
HFD2_k127_6987618_2 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000002368 193.0
HFD2_k127_6987618_3 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000001231 122.0
HFD2_k127_699428_0 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 307.0
HFD2_k127_699428_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002228 242.0
HFD2_k127_699428_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000004776 89.0
HFD2_k127_7029039_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 306.0
HFD2_k127_7029039_1 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000006059 180.0
HFD2_k127_7029039_2 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000002494 177.0
HFD2_k127_7029039_3 Anti-sigma-K factor rskA - - - 0.000000000008292 73.0
HFD2_k127_7035664_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.242e-282 879.0
HFD2_k127_7035664_1 PFAM Radical SAM - - - 5.313e-235 737.0
HFD2_k127_7035664_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000006045 186.0
HFD2_k127_7035664_11 - - - - 0.00000000000000000000000000000000000000000000002501 175.0
HFD2_k127_7035664_12 Likely ribonuclease with RNase H fold. K07447 - - 0.000000000000000000000000000009838 126.0
HFD2_k127_7035664_13 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000007248 120.0
HFD2_k127_7035664_14 - - - - 0.0000000000000000000000009875 111.0
HFD2_k127_7035664_15 von Willebrand factor, type A - - - 0.000000000000000000002119 107.0
HFD2_k127_7035664_16 - - - - 0.0000000000000000142 85.0
HFD2_k127_7035664_2 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 362.0
HFD2_k127_7035664_3 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 338.0
HFD2_k127_7035664_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
HFD2_k127_7035664_5 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 303.0
HFD2_k127_7035664_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
HFD2_k127_7035664_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005793 281.0
HFD2_k127_7035664_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000005727 264.0
HFD2_k127_7035664_9 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000009823 238.0
HFD2_k127_7037217_0 Carboxypeptidase regulatory-like domain - - - 8.226e-254 826.0
HFD2_k127_7037217_1 TIGRFAM VWFA-related Acidobacterial domain - - - 9.43e-232 742.0
HFD2_k127_7037217_10 ABC transporter K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 374.0
HFD2_k127_7037217_11 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 368.0
HFD2_k127_7037217_12 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 337.0
HFD2_k127_7037217_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007146 293.0
HFD2_k127_7037217_14 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
HFD2_k127_7037217_15 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000004285 255.0
HFD2_k127_7037217_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008279 257.0
HFD2_k127_7037217_17 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000001925 261.0
HFD2_k127_7037217_18 - - - - 0.000000000000000000000000000000000000000000000000000000008346 204.0
HFD2_k127_7037217_19 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000000000000000000000000000002232 196.0
HFD2_k127_7037217_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 571.0
HFD2_k127_7037217_20 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000002935 189.0
HFD2_k127_7037217_21 multi-organism process - - - 0.000000000000000000000000000000000000000001526 171.0
HFD2_k127_7037217_22 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000006581 158.0
HFD2_k127_7037217_23 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000004234 160.0
HFD2_k127_7037217_24 Transmembrane secretion effector - - - 0.0000000000000000000000000000000002862 139.0
HFD2_k127_7037217_25 - - - - 0.0000000000000000000000000000007886 128.0
HFD2_k127_7037217_26 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000008017 115.0
HFD2_k127_7037217_27 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000005213 107.0
HFD2_k127_7037217_28 Tfp pilus assembly protein FimV - - - 0.00000000000000000000003284 108.0
HFD2_k127_7037217_29 - - - - 0.000000000000000000002511 96.0
HFD2_k127_7037217_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 533.0
HFD2_k127_7037217_31 intermembrane phospholipid transfer K07323 - - 0.000000000000000003673 100.0
HFD2_k127_7037217_32 Belongs to the UPF0337 (CsbD) family - - - 0.000000000009157 67.0
HFD2_k127_7037217_33 - - - - 0.0000002746 53.0
HFD2_k127_7037217_34 PFAM ATP-binding region ATPase domain protein - - - 0.0000005356 55.0
HFD2_k127_7037217_35 - - - - 0.00004038 53.0
HFD2_k127_7037217_36 PEP-CTERM system TPR-repeat lipoprotein - - - 0.0005151 52.0
HFD2_k127_7037217_4 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 499.0
HFD2_k127_7037217_5 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 471.0
HFD2_k127_7037217_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 428.0
HFD2_k127_7037217_7 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 413.0
HFD2_k127_7037217_8 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 417.0
HFD2_k127_7037217_9 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 406.0
HFD2_k127_7037599_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008316 241.0
HFD2_k127_7043020_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 572.0
HFD2_k127_7043020_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 271.0
HFD2_k127_7057871_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
HFD2_k127_7057871_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000001016 164.0
HFD2_k127_7057871_2 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000001175 159.0
HFD2_k127_70757_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 587.0
HFD2_k127_70757_1 PFAM Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 418.0
HFD2_k127_70757_2 PBS lyase HEAT-like repeat - - - 0.0000001406 64.0
HFD2_k127_7079619_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 602.0
HFD2_k127_7079619_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 420.0
HFD2_k127_7079619_10 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000001209 113.0
HFD2_k127_7079619_11 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000001076 107.0
HFD2_k127_7079619_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000001506 82.0
HFD2_k127_7079619_14 Bacterial regulatory protein, Fis family - - - 0.0000000008194 63.0
HFD2_k127_7079619_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 368.0
HFD2_k127_7079619_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 370.0
HFD2_k127_7079619_4 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 326.0
HFD2_k127_7079619_5 Bacterial regulatory protein, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 304.0
HFD2_k127_7079619_6 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
HFD2_k127_7079619_7 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000004551 213.0
HFD2_k127_7079619_8 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000008809 163.0
HFD2_k127_7079619_9 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000005971 142.0
HFD2_k127_7086558_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1197.0
HFD2_k127_7086558_1 Sortilin, neurotensin receptor 3, - - - 0.0 1188.0
HFD2_k127_7086558_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 505.0
HFD2_k127_7086558_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 385.0
HFD2_k127_7086558_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
HFD2_k127_7086558_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0008097 47.0
HFD2_k127_7110271_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 350.0
HFD2_k127_7110271_1 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 322.0
HFD2_k127_7110271_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000002311 202.0
HFD2_k127_7110271_3 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000003109 199.0
HFD2_k127_7110271_4 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000002389 177.0
HFD2_k127_7110271_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000009801 169.0
HFD2_k127_7114773_0 Domain of unknown function (DUF5117) - - - 6.266e-291 910.0
HFD2_k127_7114773_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 336.0
HFD2_k127_7114773_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002003 240.0
HFD2_k127_7114773_3 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000003195 163.0
HFD2_k127_7122635_0 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005738 278.0
HFD2_k127_7122635_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
HFD2_k127_7122635_2 membrane transporter protein K07090 - - 0.000000000000000000000008265 105.0
HFD2_k127_7129_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 452.0
HFD2_k127_7129_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 380.0
HFD2_k127_7129_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 322.0
HFD2_k127_7129_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000000006717 192.0
HFD2_k127_7130012_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 487.0
HFD2_k127_7130012_1 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 341.0
HFD2_k127_7130012_2 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 325.0
HFD2_k127_7130012_3 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000008313 160.0
HFD2_k127_7130012_5 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000003697 68.0
HFD2_k127_713329_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 444.0
HFD2_k127_713329_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 423.0
HFD2_k127_713329_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 363.0
HFD2_k127_713329_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 301.0
HFD2_k127_713329_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
HFD2_k127_713329_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HFD2_k127_713329_6 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000005715 213.0
HFD2_k127_713329_7 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000001607 148.0
HFD2_k127_713329_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000001316 116.0
HFD2_k127_713329_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000004471 110.0
HFD2_k127_7198905_0 Malate synthase K01638 - 2.3.3.9 3.217e-221 698.0
HFD2_k127_7198905_1 Isocitrate lyase family K01637 - 4.1.3.1 7.892e-197 624.0
HFD2_k127_7198905_2 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 546.0
HFD2_k127_7198905_3 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001925 259.0
HFD2_k127_7198905_4 Transcriptional regulator IclR K13641 - - 0.0000000000000000000000000000000000000000000000000000000000295 214.0
HFD2_k127_7198905_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000002847 163.0
HFD2_k127_7198905_6 ig-like, plexins, transcription factors - - - 0.0000000000000861 86.0
HFD2_k127_7198905_7 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.00000005646 64.0
HFD2_k127_7198905_8 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000009213 52.0
HFD2_k127_7230477_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 469.0
HFD2_k127_7230477_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 402.0
HFD2_k127_7230477_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 395.0
HFD2_k127_7241756_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 588.0
HFD2_k127_7241756_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 321.0
HFD2_k127_7241756_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000002272 220.0
HFD2_k127_7241756_3 HYR domain - - - 0.0000000000000000000000000000000000000000000000000000006817 222.0
HFD2_k127_7241756_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000004221 140.0
HFD2_k127_7241756_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001333 135.0
HFD2_k127_7241756_6 Tetratricopeptide repeat - - - 0.00000000000003636 85.0
HFD2_k127_7241756_7 - - - - 0.0000000000041 70.0
HFD2_k127_7246579_0 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 377.0
HFD2_k127_7246579_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 351.0
HFD2_k127_7247045_0 MacB-like periplasmic core domain - - - 5.795e-262 829.0
HFD2_k127_7247045_1 efflux transmembrane transporter activity - - - 7.961e-217 700.0
HFD2_k127_7247045_2 efflux transmembrane transporter activity - - - 7.201e-210 677.0
HFD2_k127_7247045_3 MacB-like periplasmic core domain - - - 1.026e-207 674.0
HFD2_k127_7247045_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000005194 166.0
HFD2_k127_7247045_5 MacB-like periplasmic core domain - - - 0.0000000000006303 70.0
HFD2_k127_7314041_0 Tricorn protease homolog K08676 - - 0.0 1515.0
HFD2_k127_7314041_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000006055 156.0
HFD2_k127_7321167_0 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000006849 138.0
HFD2_k127_733343_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 479.0
HFD2_k127_733343_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 264.0
HFD2_k127_733343_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 259.0
HFD2_k127_733343_3 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000158 198.0
HFD2_k127_733343_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000003018 138.0
HFD2_k127_7362749_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 562.0
HFD2_k127_7362749_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 529.0
HFD2_k127_7362749_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 298.0
HFD2_k127_7367857_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611,K09065 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 477.0
HFD2_k127_7367857_1 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 463.0
HFD2_k127_7367857_2 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 387.0
HFD2_k127_7367857_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 319.0
HFD2_k127_7367857_4 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 316.0
HFD2_k127_7367857_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 311.0
HFD2_k127_7367857_6 Peptidase dimerisation domain - - - 0.00000006963 55.0
HFD2_k127_7370724_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 517.0
HFD2_k127_7370724_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 299.0
HFD2_k127_7370724_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
HFD2_k127_7388660_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 2.52e-303 947.0
HFD2_k127_7388660_1 GTP-binding protein TypA K06207 - - 1.962e-276 863.0
HFD2_k127_7388660_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002845 221.0
HFD2_k127_7388660_3 Bacterial Ig-like domain (group 3) - - - 0.00000004881 66.0
HFD2_k127_7388660_4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00001138 54.0
HFD2_k127_738976_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 536.0
HFD2_k127_738976_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 334.0
HFD2_k127_738976_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000001146 157.0
HFD2_k127_738976_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000001592 143.0
HFD2_k127_738976_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000003493 137.0
HFD2_k127_738976_13 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000001136 128.0
HFD2_k127_738976_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000004719 101.0
HFD2_k127_738976_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000003599 89.0
HFD2_k127_738976_16 Ribosomal protein L30p/L7e K02907 - - 0.000000000003464 70.0
HFD2_k127_738976_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000006023 54.0
HFD2_k127_738976_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000329 259.0
HFD2_k127_738976_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
HFD2_k127_738976_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000008163 218.0
HFD2_k127_738976_5 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
HFD2_k127_738976_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000001511 214.0
HFD2_k127_738976_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000002636 192.0
HFD2_k127_738976_8 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000002018 183.0
HFD2_k127_738976_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000002528 176.0
HFD2_k127_739711_0 ASPIC and UnbV - - - 1.5e-323 1026.0
HFD2_k127_739711_1 PFAM photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 392.0
HFD2_k127_739711_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000191 170.0
HFD2_k127_739711_3 PFAM PfkB domain protein K00852 - 2.7.1.15 0.000000000000000000000000000000000002753 151.0
HFD2_k127_739711_4 Iodothyronine deiodinase - - - 0.00000000000000000000000000000001491 130.0
HFD2_k127_739711_5 - - - - 0.000000000000000000000001711 109.0
HFD2_k127_739711_6 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000001748 66.0
HFD2_k127_7406565_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 2.539e-225 709.0
HFD2_k127_7406565_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 542.0
HFD2_k127_7406565_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 469.0
HFD2_k127_7406565_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 327.0
HFD2_k127_7406565_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000001666 244.0
HFD2_k127_7406565_5 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000001655 224.0
HFD2_k127_7406565_6 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000004228 232.0
HFD2_k127_7411788_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 321.0
HFD2_k127_7411788_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 315.0
HFD2_k127_7411788_2 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002972 283.0
HFD2_k127_7411788_3 ATP:ADP antiporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005885 295.0
HFD2_k127_7411788_4 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000001055 104.0
HFD2_k127_7411788_5 DinB family - - - 0.000000001192 67.0
HFD2_k127_7411788_6 - - - - 0.000007814 57.0
HFD2_k127_7411788_7 PilZ domain K02676 - - 0.00007675 52.0
HFD2_k127_7413167_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 422.0
HFD2_k127_7413167_1 PFAM NAD dependent epimerase dehydratase family K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
HFD2_k127_7413167_10 PFAM TPR repeat-containing protein - - - 0.00000000001454 72.0
HFD2_k127_7413167_2 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 357.0
HFD2_k127_7413167_3 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 293.0
HFD2_k127_7413167_4 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005548 284.0
HFD2_k127_7413167_5 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000000000008319 271.0
HFD2_k127_7413167_6 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000101 237.0
HFD2_k127_7413167_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000142 171.0
HFD2_k127_7413167_8 - - - - 0.000000000000000000000000000000000000000005481 161.0
HFD2_k127_7413167_9 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.00000000000000000000000000000000009171 149.0
HFD2_k127_7421350_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 634.0
HFD2_k127_7421350_1 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
HFD2_k127_7421350_2 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000008845 235.0
HFD2_k127_742217_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 537.0
HFD2_k127_742217_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001278 267.0
HFD2_k127_742644_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.351e-234 740.0
HFD2_k127_742644_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.265e-203 655.0
HFD2_k127_742644_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000002449 205.0
HFD2_k127_742644_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K00980,K03272 - 2.7.1.167,2.7.7.39,2.7.7.70 0.0000000000000000000000000000000000000000008476 168.0
HFD2_k127_742644_12 S1 P1 Nuclease - - - 0.0000000000000000000000000000000001572 144.0
HFD2_k127_742644_13 Phospholipid methyltransferase - - - 0.0000000000000000000000000000001088 134.0
HFD2_k127_742644_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000002625 99.0
HFD2_k127_742644_15 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000001531 76.0
HFD2_k127_742644_16 - - - - 0.0000000003699 68.0
HFD2_k127_742644_17 tRNA processing K06864 - - 0.0000001315 56.0
HFD2_k127_742644_18 - - - - 0.0006451 50.0
HFD2_k127_742644_2 amino acid K03294 - - 1.268e-202 643.0
HFD2_k127_742644_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 414.0
HFD2_k127_742644_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 296.0
HFD2_k127_742644_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001014 284.0
HFD2_k127_742644_6 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
HFD2_k127_742644_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000001762 254.0
HFD2_k127_742644_8 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000004699 215.0
HFD2_k127_742644_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000008798 198.0
HFD2_k127_7427220_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 8.13e-207 649.0
HFD2_k127_7427220_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
HFD2_k127_7427220_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000007851 95.0
HFD2_k127_7427220_3 Putative modulator of DNA gyrase K03568 - - 0.00000000000001899 75.0
HFD2_k127_7473874_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001084 264.0
HFD2_k127_7473874_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001186 239.0
HFD2_k127_7473874_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000007551 168.0
HFD2_k127_7473874_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000003472 76.0
HFD2_k127_7477735_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
HFD2_k127_7477735_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000006343 87.0
HFD2_k127_7477735_2 Periplasmic or secreted lipoprotein - - - 0.00000001096 65.0
HFD2_k127_7506946_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000001572 177.0
HFD2_k127_7506946_1 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000001424 140.0
HFD2_k127_7530581_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 438.0
HFD2_k127_7530581_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003413 269.0
HFD2_k127_7530581_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000002579 171.0
HFD2_k127_7530581_3 Yip1 domain - - - 0.000000000000000000001434 105.0
HFD2_k127_7530581_4 Preprotein translocase, YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000002405 92.0
HFD2_k127_7530581_5 - - - - 0.0000004624 60.0
HFD2_k127_7546864_0 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000001665 171.0
HFD2_k127_7546864_1 PFAM heat shock protein DnaJ K04082 - - 0.0000000000000000000000000000000000000000000001387 179.0
HFD2_k127_7546864_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000005799 153.0
HFD2_k127_7546864_3 heat shock protein 70 K04043,K04044 - - 0.0000000000000000000000000000001372 126.0
HFD2_k127_7561560_0 transferase activity, transferring glycosyl groups - - - 2.268e-297 933.0
HFD2_k127_7561560_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 529.0
HFD2_k127_7565859_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1032.0
HFD2_k127_7565859_1 Belongs to the UbiD family K03182 - 4.1.1.98 2.553e-224 703.0
HFD2_k127_756693_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 546.0
HFD2_k127_756693_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 526.0
HFD2_k127_756693_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 381.0
HFD2_k127_756693_3 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 365.0
HFD2_k127_756693_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000004859 134.0
HFD2_k127_7569777_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000002363 150.0
HFD2_k127_7569777_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000003276 79.0
HFD2_k127_7575348_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006857 282.0
HFD2_k127_7575348_1 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000003466 166.0
HFD2_k127_7575348_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02484,K02660,K07653,K07654,K11617 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0035556,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046983,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070297,GO:0070298,GO:0071704,GO:0140096,GO:1901564,GO:1902531,GO:1902532 2.7.13.3 0.000000007979 64.0
HFD2_k127_7621363_0 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 363.0
HFD2_k127_7621363_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 329.0
HFD2_k127_7621363_2 metallophosphoesterase K07096,K07496 - - 0.00000000000000000000000000000000000000000000000000000000000009561 218.0
HFD2_k127_7621363_3 membrane-bound metal-dependent K07038 - - 0.00000000000000000000006026 112.0
HFD2_k127_7628686_0 Tricorn protease homolog - - - 3.56e-322 1013.0
HFD2_k127_7628686_1 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 323.0
HFD2_k127_7631769_0 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 314.0
HFD2_k127_7631769_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002929 272.0
HFD2_k127_7631769_2 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000006571 183.0
HFD2_k127_7631769_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000001068 170.0
HFD2_k127_7631769_4 AMP binding - - - 0.0000000001107 68.0
HFD2_k127_7640440_0 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 431.0
HFD2_k127_7640440_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 317.0
HFD2_k127_7640440_2 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000001158 102.0
HFD2_k127_7640440_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001058 102.0
HFD2_k127_7640440_4 Dehydrogenase - - - 0.000000000000000001466 96.0
HFD2_k127_7653295_0 Glycogen debranching enzyme N terminal - - - 2.95e-202 638.0
HFD2_k127_7653295_1 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 542.0
HFD2_k127_7657201_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 477.0
HFD2_k127_7657201_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000004139 224.0
HFD2_k127_7657201_2 Tail sheath protein K06907 - - 0.00005495 48.0
HFD2_k127_7668061_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 580.0
HFD2_k127_7668061_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 578.0
HFD2_k127_7668061_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 475.0
HFD2_k127_7668061_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 370.0
HFD2_k127_7668061_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000005535 190.0
HFD2_k127_7668061_5 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000235 132.0
HFD2_k127_7668061_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000002323 117.0
HFD2_k127_7668061_7 Pfam:DUF1311 - - - 0.0000000003842 66.0
HFD2_k127_7671823_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2e-253 794.0
HFD2_k127_7671823_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 466.0
HFD2_k127_7671823_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000004086 141.0
HFD2_k127_7671823_11 Protein of unknown function (DUF2905) - - - 0.0000000000003999 71.0
HFD2_k127_7671823_12 Bacterial virulence protein (VirJ) - - - 0.00000001012 66.0
HFD2_k127_7671823_2 Belongs to the thiolase family K07508 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 438.0
HFD2_k127_7671823_3 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 421.0
HFD2_k127_7671823_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 406.0
HFD2_k127_7671823_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 381.0
HFD2_k127_7671823_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000001804 175.0
HFD2_k127_7671823_7 BON domain - - - 0.00000000000000000000000000000000000000000000005506 175.0
HFD2_k127_7671823_8 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000008178 182.0
HFD2_k127_7671823_9 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000006229 151.0
HFD2_k127_7677361_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 486.0
HFD2_k127_7677361_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000007753 93.0
HFD2_k127_7677361_2 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000007216 86.0
HFD2_k127_7677361_3 PFAM Septum formation initiator K05589 - - 0.00000003136 64.0
HFD2_k127_7678358_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.239e-208 673.0
HFD2_k127_7678358_1 - - - - 0.00000000000000000000000000002186 123.0
HFD2_k127_7679932_0 Protein kinase domain K12132 - 2.7.11.1 4.281e-281 892.0
HFD2_k127_7679932_1 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 318.0
HFD2_k127_7679932_2 response to abiotic stimulus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004019 262.0
HFD2_k127_7679932_3 - - - - 0.00000000000000000000000000000000000001106 151.0
HFD2_k127_7679932_4 Uncharacterised ArCR, COG2043 - - - 0.00004127 47.0
HFD2_k127_7685869_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000001085 123.0
HFD2_k127_7685869_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001051 121.0
HFD2_k127_7693825_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 361.0
HFD2_k127_7693825_1 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
HFD2_k127_7693825_2 Peptidase dimerisation domain - - - 0.0000000000002467 70.0
HFD2_k127_769557_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 397.0
HFD2_k127_769557_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 309.0
HFD2_k127_769557_2 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.000000000000000000000000000000000000000000000000006863 184.0
HFD2_k127_770543_0 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HFD2_k127_770543_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000004431 210.0
HFD2_k127_770543_2 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000001103 173.0
HFD2_k127_7722060_0 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 3.4e-202 650.0
HFD2_k127_7722060_1 Cellulose synthase K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 374.0
HFD2_k127_7722060_2 Tetratricopeptide repeat - - - 0.0000001056 63.0
HFD2_k127_7724109_0 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 314.0
HFD2_k127_7724109_1 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007352 255.0
HFD2_k127_7724109_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000424 182.0
HFD2_k127_7724109_3 Forkhead associated domain - - - 0.000000000000000000000000000007883 134.0
HFD2_k127_7724109_4 NACHT domain - - - 0.000000000000000000001029 109.0
HFD2_k127_7728752_0 Dienelactone hydrolase family - - - 1.341e-223 704.0
HFD2_k127_774212_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 351.0
HFD2_k127_7754009_0 His Kinase A (phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 621.0
HFD2_k127_7754009_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
HFD2_k127_7754009_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 336.0
HFD2_k127_7754009_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 252.0
HFD2_k127_7754009_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000007273 229.0
HFD2_k127_7754009_5 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000009705 196.0
HFD2_k127_7754009_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000004997 100.0
HFD2_k127_7754009_7 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000008822 94.0
HFD2_k127_7754009_8 cheY-homologous receiver domain - - - 0.000000000000004976 85.0
HFD2_k127_7761763_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 501.0
HFD2_k127_7761763_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 443.0
HFD2_k127_7761763_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000004979 230.0
HFD2_k127_7761763_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
HFD2_k127_7761763_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001799 161.0
HFD2_k127_7761763_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000004481 156.0
HFD2_k127_7761763_6 Pathogenicity locus - - - 0.000000000000000000000002956 106.0
HFD2_k127_7781475_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 1.104e-197 629.0
HFD2_k127_7781475_1 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 581.0
HFD2_k127_7781475_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000005704 153.0
HFD2_k127_7781475_3 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.0000000000000000000000000000000000003524 147.0
HFD2_k127_7781475_4 Tetratricopeptide repeat - - - 0.00000000000000000001106 95.0
HFD2_k127_7792201_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 504.0
HFD2_k127_7794167_0 Nitrate reductase alpha subunit K17050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 406.0
HFD2_k127_7794167_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007838 293.0
HFD2_k127_7794167_2 PFAM Cytochrome b b6 domain - - - 0.000000000000003514 76.0
HFD2_k127_7843986_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 346.0
HFD2_k127_7843986_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 328.0
HFD2_k127_7864982_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.006e-236 738.0
HFD2_k127_7864982_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 529.0
HFD2_k127_7864982_2 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 471.0
HFD2_k127_7864982_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 381.0
HFD2_k127_7864982_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 326.0
HFD2_k127_7864982_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004256 261.0
HFD2_k127_7864982_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000122 171.0
HFD2_k127_7864982_7 Methylated dna-protein cysteine methyltransferase K07443 - - 0.00000000000000004439 86.0
HFD2_k127_7864982_8 ABC-2 family transporter protein - - - 0.000002144 56.0
HFD2_k127_7879195_0 general secretion pathway protein - - - 0.00000000000000000000000000001003 128.0
HFD2_k127_7879195_1 Transglycosylase SLT domain - - - 0.000000000000000002472 85.0
HFD2_k127_7879195_2 - - - - 0.00000000000000001246 89.0
HFD2_k127_7879195_3 - K02664 - - 0.00000000001098 72.0
HFD2_k127_7879195_4 PFAM Fimbrial assembly family protein K02663 - - 0.00000000003206 72.0
HFD2_k127_788014_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 364.0
HFD2_k127_788014_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000592 177.0
HFD2_k127_7895894_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 301.0
HFD2_k127_7895894_1 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000003116 206.0
HFD2_k127_7906716_0 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000005489 108.0
HFD2_k127_7911589_0 SPFH domain / Band 7 family - - - 5.349e-244 773.0
HFD2_k127_7911589_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 449.0
HFD2_k127_7911589_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 324.0
HFD2_k127_7911589_3 polyphosphate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HFD2_k127_7911589_4 - - - - 0.000000000000000000000000000000000000000000000002433 179.0
HFD2_k127_7911589_6 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.00000001691 68.0
HFD2_k127_7911589_7 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.000008203 51.0
HFD2_k127_7914103_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 566.0
HFD2_k127_7914103_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 404.0
HFD2_k127_7914103_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 349.0
HFD2_k127_7922692_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 401.0
HFD2_k127_7922692_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 402.0
HFD2_k127_7936803_0 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 327.0
HFD2_k127_7936803_1 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.000000004754 62.0
HFD2_k127_7936803_2 Redoxin - - - 0.0001734 48.0
HFD2_k127_7950581_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.052e-225 713.0
HFD2_k127_7957563_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 399.0
HFD2_k127_7957563_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000001015 185.0
HFD2_k127_7957563_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004323 162.0
HFD2_k127_7957563_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000002334 126.0
HFD2_k127_7960792_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
HFD2_k127_7960792_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
HFD2_k127_7960792_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
HFD2_k127_7960792_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000002247 183.0
HFD2_k127_7960792_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000002004 136.0
HFD2_k127_7983496_0 Glycosyl transferase family 21 K11936 - - 2.246e-294 940.0
HFD2_k127_7985295_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 618.0
HFD2_k127_7985295_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 585.0
HFD2_k127_7985295_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 514.0
HFD2_k127_7985295_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 338.0
HFD2_k127_7985295_4 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003341 269.0
HFD2_k127_7985295_5 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000366 273.0
HFD2_k127_7985295_6 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000000002412 195.0
HFD2_k127_7985295_7 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000002002 70.0
HFD2_k127_7985721_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 266.0
HFD2_k127_7985721_1 PA domain - - - 0.000000000000000000000000000000000000000000000000001567 188.0
HFD2_k127_7985721_2 PFAM ribonuclease K07058 - - 0.000000000000000000009884 100.0
HFD2_k127_7985721_3 - - - - 0.00000000000001666 78.0
HFD2_k127_7985972_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1271.0
HFD2_k127_7985972_1 Surface antigen variable number K07277 - - 1.461e-236 768.0
HFD2_k127_7985972_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004639 256.0
HFD2_k127_7985972_3 Protein of unknown function (DUF1800) - - - 0.00001685 58.0
HFD2_k127_7987084_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 494.0
HFD2_k127_7987084_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 472.0
HFD2_k127_7987084_2 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 365.0
HFD2_k127_7987084_3 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 370.0
HFD2_k127_798877_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 582.0
HFD2_k127_798877_1 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 471.0
HFD2_k127_798877_2 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001565 248.0
HFD2_k127_798877_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000003996 194.0
HFD2_k127_798877_4 - - - - 0.00001637 55.0
HFD2_k127_7989257_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 287.0
HFD2_k127_7989257_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000001258 237.0
HFD2_k127_7989257_2 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000001279 132.0
HFD2_k127_7989257_3 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000004845 128.0
HFD2_k127_7989257_4 hydrolase K07025 - - 0.000000000000000000000000701 109.0
HFD2_k127_7989257_5 PFAM AsmA family protein K07289 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.00000000000000000000009854 114.0
HFD2_k127_7989257_6 CAAX protease self-immunity K07052 - - 0.0000001794 61.0
HFD2_k127_8028108_0 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000002499 113.0
HFD2_k127_8028108_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000006545 75.0
HFD2_k127_804185_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 550.0
HFD2_k127_804185_1 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001188 218.0
HFD2_k127_804185_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000001099 153.0
HFD2_k127_8056458_0 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 569.0
HFD2_k127_8056458_1 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 375.0
HFD2_k127_8056458_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000902 255.0
HFD2_k127_8056458_3 Tetratricopeptide repeat - - - 0.00001913 54.0
HFD2_k127_8056458_4 Histidine kinase - - - 0.0003345 45.0
HFD2_k127_8086439_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
HFD2_k127_8086439_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 334.0
HFD2_k127_8086439_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000001214 179.0
HFD2_k127_8091826_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1166.0
HFD2_k127_8091826_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 461.0
HFD2_k127_8091826_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 413.0
HFD2_k127_8091826_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 368.0
HFD2_k127_8091826_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000001256 97.0
HFD2_k127_8100930_0 Radical SAM - - - 8.379e-226 713.0
HFD2_k127_8100930_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004913 259.0
HFD2_k127_8100930_2 Putative regulatory protein - - - 0.0000009727 54.0
HFD2_k127_8119054_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000002884 271.0
HFD2_k127_8119054_1 - - - - 0.0000000000000000000000000002589 117.0
HFD2_k127_8152487_0 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 431.0
HFD2_k127_8152487_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
HFD2_k127_8152487_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007091 238.0
HFD2_k127_8152487_3 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000000000001602 209.0
HFD2_k127_8152487_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000002406 179.0
HFD2_k127_8167707_0 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 493.0
HFD2_k127_8167707_1 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 301.0
HFD2_k127_8167707_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000002911 179.0
HFD2_k127_8167707_3 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000002171 141.0
HFD2_k127_8167707_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000001857 86.0
HFD2_k127_8167707_5 Protein of unknown function (DUF3108) - - - 0.000000002727 68.0
HFD2_k127_8170838_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 434.0
HFD2_k127_8170838_1 alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
HFD2_k127_8170838_10 Domain of unknown function (DUF4440) - - - 0.00000000000003628 81.0
HFD2_k127_8170838_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 345.0
HFD2_k127_8170838_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
HFD2_k127_8170838_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000007909 220.0
HFD2_k127_8170838_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000004013 214.0
HFD2_k127_8170838_6 - - - - 0.00000000000000000000000000000000000000000000000000004435 199.0
HFD2_k127_8170838_7 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000001034 186.0
HFD2_k127_8170838_8 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively - - - 0.0000000000000000000000002684 120.0
HFD2_k127_8170838_9 Tetratricopeptide repeats - - - 0.000000000000000000000001175 119.0
HFD2_k127_8249466_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 293.0
HFD2_k127_8249466_1 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000004257 216.0
HFD2_k127_8263216_0 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 449.0
HFD2_k127_8263216_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004041 270.0
HFD2_k127_8263216_2 ABC transporter K02003 - - 0.00000000000000000000000000000000009574 134.0
HFD2_k127_8263472_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.28e-320 1020.0
HFD2_k127_8263472_1 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 599.0
HFD2_k127_8263472_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000001724 100.0
HFD2_k127_8263472_11 Dodecin K09165 - - 0.0000009622 53.0
HFD2_k127_8263472_12 Thioesterase domain K00627 - 2.3.1.12 0.00002588 57.0
HFD2_k127_8263472_13 CHAD - - - 0.0003616 53.0
HFD2_k127_8263472_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 328.0
HFD2_k127_8263472_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 303.0
HFD2_k127_8263472_4 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001625 212.0
HFD2_k127_8263472_5 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000000002128 193.0
HFD2_k127_8263472_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000005928 182.0
HFD2_k127_8263472_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000008751 143.0
HFD2_k127_8263472_8 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000004975 105.0
HFD2_k127_8263472_9 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000001018 97.0
HFD2_k127_8277423_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 615.0
HFD2_k127_8277423_1 - - - - 0.00000000000000000000000000000000000002681 156.0
HFD2_k127_8277423_2 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000002393 141.0
HFD2_k127_8289525_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 346.0
HFD2_k127_8289525_1 oxidoreductase activity K12511 - - 0.0000000000000000000000004828 119.0
HFD2_k127_8289525_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000009697 87.0
HFD2_k127_8289525_3 von Willebrand factor (vWF) type A domain - - - 0.0000004615 59.0
HFD2_k127_8289525_4 peptidyl-tyrosine sulfation - - - 0.00001523 56.0
HFD2_k127_8310290_0 succinyl-diaminopimelate desuccinylase activity K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
HFD2_k127_8310290_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 304.0
HFD2_k127_8310290_10 - - - - 0.000000001135 67.0
HFD2_k127_8310290_11 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.000000002342 71.0
HFD2_k127_8310290_12 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.00000002461 63.0
HFD2_k127_8310290_13 Pilus assembly protein PilX K02673 - - 0.00000003187 66.0
HFD2_k127_8310290_14 pilus assembly protein PilW K02672 - - 0.00006231 54.0
HFD2_k127_8310290_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000006689 239.0
HFD2_k127_8310290_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000009121 215.0
HFD2_k127_8310290_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000006634 203.0
HFD2_k127_8310290_5 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000002465 170.0
HFD2_k127_8310290_6 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.0000000000000000004091 94.0
HFD2_k127_8310290_7 MoaE protein K21142 - 2.8.1.12 0.00000000000004402 78.0
HFD2_k127_8310290_8 - - - - 0.00000000001573 72.0
HFD2_k127_8310290_9 protein import - - - 0.00000000004335 75.0
HFD2_k127_8320322_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000001518 200.0
HFD2_k127_8320322_1 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000006517 134.0
HFD2_k127_8320322_2 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000002183 82.0
HFD2_k127_8320322_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000001306 66.0
HFD2_k127_8329386_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000001618 222.0
HFD2_k127_8329386_1 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000007712 198.0
HFD2_k127_8329386_2 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000006766 179.0
HFD2_k127_8387813_0 AcrB/AcrD/AcrF family K03296 - - 8.57e-221 702.0
HFD2_k127_8387813_1 Phosphotransferase enzyme family - - - 0.000000000002196 67.0
HFD2_k127_841731_0 lipopolysaccharide transport K22110 - - 1.384e-291 904.0
HFD2_k127_841731_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000001899 230.0
HFD2_k127_843665_2 COG1555 DNA uptake protein and related DNA-binding proteins - - - 0.00000000000000004143 90.0
HFD2_k127_843665_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00003188 55.0
HFD2_k127_8467350_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 433.0
HFD2_k127_8467350_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 323.0
HFD2_k127_8467350_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000002979 171.0
HFD2_k127_8467350_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000475 158.0
HFD2_k127_8467350_4 Tetratricopeptide repeat - - - 0.0000008193 61.0
HFD2_k127_8467350_5 Tetratricopeptide repeat - - - 0.000001314 60.0
HFD2_k127_8503549_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 315.0
HFD2_k127_8503549_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000009902 239.0
HFD2_k127_8503549_2 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000002642 143.0
HFD2_k127_8503549_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000005422 132.0
HFD2_k127_8503549_4 tRNA synthetases class I (K) K01870 - 6.1.1.5 0.00000000000000002255 84.0
HFD2_k127_851904_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006833 277.0
HFD2_k127_851904_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000003217 190.0
HFD2_k127_851904_2 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000005144 131.0
HFD2_k127_8519372_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.266e-230 721.0
HFD2_k127_8519372_1 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 637.0
HFD2_k127_8519372_10 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000001449 79.0
HFD2_k127_8519372_11 uracil, thiamine, allantoin K03457 - - 0.00000001887 58.0
HFD2_k127_8519372_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 529.0
HFD2_k127_8519372_3 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 489.0
HFD2_k127_8519372_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 446.0
HFD2_k127_8519372_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 377.0
HFD2_k127_8519372_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 338.0
HFD2_k127_8519372_7 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000846 282.0
HFD2_k127_8519372_8 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001286 248.0
HFD2_k127_8541112_0 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 387.0
HFD2_k127_8541112_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 408.0
HFD2_k127_8541112_2 Bacterial regulatory protein, Fis family - - - 0.0000000000008535 73.0
HFD2_k127_8548624_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 510.0
HFD2_k127_8548624_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 409.0
HFD2_k127_8548624_10 B3/4 domain K04567 - 6.1.1.6 0.0000000000000000000000000000000000001806 150.0
HFD2_k127_8548624_11 cell redox homeostasis - - - 0.00000000000000000000000004737 116.0
HFD2_k127_8548624_12 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000001728 102.0
HFD2_k127_8548624_13 Trm112p-like protein K09791 - - 0.000000000000000000001827 96.0
HFD2_k127_8548624_2 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 339.0
HFD2_k127_8548624_3 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 294.0
HFD2_k127_8548624_4 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
HFD2_k127_8548624_5 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000363 203.0
HFD2_k127_8548624_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000002386 172.0
HFD2_k127_8548624_7 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000001358 176.0
HFD2_k127_8548624_8 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000002961 177.0
HFD2_k127_8548624_9 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000000006253 152.0
HFD2_k127_8571859_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000004315 242.0
HFD2_k127_8571859_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001881 218.0
HFD2_k127_8571859_2 Tetratricopeptide repeat - - - 0.00006771 53.0
HFD2_k127_862640_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 427.0
HFD2_k127_862640_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001892 234.0
HFD2_k127_8633712_0 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
HFD2_k127_8633712_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000007174 238.0
HFD2_k127_8633712_2 very-long-chain-acyl-CoA dehydrogenase activity K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000207 196.0
HFD2_k127_8639555_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 528.0
HFD2_k127_8639555_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 324.0
HFD2_k127_8639555_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000002527 189.0
HFD2_k127_8652757_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.941e-229 720.0
HFD2_k127_8652757_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 304.0
HFD2_k127_8652757_2 RDD family - - - 0.0000000000000000000000000000001118 133.0
HFD2_k127_8652757_3 methylamine metabolic process K15977 - - 0.0000000000000000000000000691 112.0
HFD2_k127_8652757_4 Phage shock protein C, PspC K03973 - - 0.00000000000001601 78.0
HFD2_k127_8653350_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 272.0
HFD2_k127_8653350_1 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000009991 238.0
HFD2_k127_8653350_2 cheY-homologous receiver domain - - - 0.00000000000000000000000001879 113.0
HFD2_k127_8653350_3 PASTA domain K12132 - 2.7.11.1 0.00000000004552 66.0
HFD2_k127_8667181_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 380.0
HFD2_k127_8667181_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 361.0
HFD2_k127_8667181_2 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 334.0
HFD2_k127_8667181_3 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
HFD2_k127_8667181_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
HFD2_k127_8695417_0 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 525.0
HFD2_k127_8695417_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 343.0
HFD2_k127_8695417_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000001319 153.0
HFD2_k127_8702186_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.776e-269 847.0
HFD2_k127_8702186_1 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 424.0
HFD2_k127_8702186_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000009522 114.0
HFD2_k127_8714002_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
HFD2_k127_8714002_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001077 212.0
HFD2_k127_8714002_2 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000003235 150.0
HFD2_k127_8714002_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000001709 133.0
HFD2_k127_8744863_0 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 410.0
HFD2_k127_8744863_1 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000003082 83.0
HFD2_k127_8748009_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 393.0
HFD2_k127_8748009_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD2_k127_8758558_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008249 251.0
HFD2_k127_8758558_1 - - - - 0.00000000000000000000000000000000000000000000000000000000005616 209.0
HFD2_k127_8758558_2 - - - - 0.00000000000000000000000000000000000000000004075 168.0
HFD2_k127_8758558_3 - - - - 0.0000000000000000001145 96.0
HFD2_k127_8758558_4 PFAM Pentapeptide repeats (8 copies) - - - 0.000003081 56.0
HFD2_k127_879197_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1651.0
HFD2_k127_879197_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 6.782e-261 822.0
HFD2_k127_879197_10 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000003116 190.0
HFD2_k127_879197_11 - - - - 0.0000000000000000000000000000000002678 141.0
HFD2_k127_879197_12 LysM domain K08307,K12204 - - 0.00000000000000000000000000000001528 142.0
HFD2_k127_879197_13 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000259 127.0
HFD2_k127_879197_14 PFAM BNR Asp-box repeat - - - 0.00000002691 66.0
HFD2_k127_879197_15 Transcriptional regulator, DeoR family K21601 - - 0.000002044 59.0
HFD2_k127_879197_16 response to antibiotic - - - 0.00006845 52.0
HFD2_k127_879197_2 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 3.678e-204 663.0
HFD2_k127_879197_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 428.0
HFD2_k127_879197_4 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 365.0
HFD2_k127_879197_5 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
HFD2_k127_879197_6 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 359.0
HFD2_k127_879197_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005686 274.0
HFD2_k127_879197_8 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000000000001093 205.0
HFD2_k127_879197_9 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000004089 198.0
HFD2_k127_88478_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.021e-262 829.0
HFD2_k127_88478_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 619.0
HFD2_k127_88478_10 PFAM response regulator receiveR - - - 0.000000000000000000000000000000000000000000000000001537 189.0
HFD2_k127_88478_11 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000009018 140.0
HFD2_k127_88478_12 diguanylate cyclase - - - 0.00000000000000000000000000000000003368 145.0
HFD2_k127_88478_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000007577 134.0
HFD2_k127_88478_14 phosphorelay signal transduction system - - - 0.0000000000000000000003834 103.0
HFD2_k127_88478_15 STAS domain K04749 - - 0.000000000000000000009095 97.0
HFD2_k127_88478_16 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000001169 78.0
HFD2_k127_88478_17 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000166 71.0
HFD2_k127_88478_18 MlaD protein K02067 - - 0.000000001169 69.0
HFD2_k127_88478_19 addiction module antidote protein, HigA family K21498 - - 0.0000002164 56.0
HFD2_k127_88478_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 449.0
HFD2_k127_88478_20 Permease MlaE K02066 - - 0.0007844 42.0
HFD2_k127_88478_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 410.0
HFD2_k127_88478_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 367.0
HFD2_k127_88478_5 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 367.0
HFD2_k127_88478_6 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 307.0
HFD2_k127_88478_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
HFD2_k127_88478_8 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001881 241.0
HFD2_k127_88478_9 Endonuclease V K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000002297 214.0
HFD2_k127_887339_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 612.0
HFD2_k127_887339_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 587.0
HFD2_k127_887339_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 529.0
HFD2_k127_887339_3 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 477.0
HFD2_k127_887339_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 477.0
HFD2_k127_887339_5 Prolyl oligopeptidase K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 308.0
HFD2_k127_887339_6 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
HFD2_k127_891036_0 Cytochrome c - - - 0.0 1064.0
HFD2_k127_891036_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 461.0
HFD2_k127_891036_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005562 274.0
HFD2_k127_891036_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 260.0
HFD2_k127_891036_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009365 235.0
HFD2_k127_891036_5 heme a metabolic process K02259,K03110 - - 0.000000000000000000000000000000000000000000000000001139 195.0
HFD2_k127_891036_6 Protein of unknown function (DUF420) K08976 - - 0.000007923 49.0
HFD2_k127_895243_0 PUA-like domain K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 452.0
HFD2_k127_895243_1 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004913 298.0
HFD2_k127_895243_2 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000001155 258.0
HFD2_k127_895243_3 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000004817 240.0
HFD2_k127_895243_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000004055 153.0
HFD2_k127_895243_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000009269 150.0
HFD2_k127_9112_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1332.0
HFD2_k127_9112_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 1.418e-248 795.0
HFD2_k127_9112_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 575.0
HFD2_k127_9112_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 361.0
HFD2_k127_9112_4 Outer membrane efflux protein K12340,K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 302.0
HFD2_k127_9112_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001811 255.0
HFD2_k127_9112_6 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000007022 222.0
HFD2_k127_9112_7 DNA-templated transcription, initiation K03088 - - 0.00000000000002581 82.0
HFD2_k127_914349_0 4Fe-4S dicluster domain K00184 - - 0.0 1156.0
HFD2_k127_914349_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.789e-279 865.0
HFD2_k127_914349_10 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000004641 147.0
HFD2_k127_914349_11 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000000000000000005475 92.0
HFD2_k127_914349_12 - - - - 0.000000000000000001931 93.0
HFD2_k127_914349_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 409.0
HFD2_k127_914349_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 374.0
HFD2_k127_914349_4 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 301.0
HFD2_k127_914349_5 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
HFD2_k127_914349_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HFD2_k127_914349_7 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 259.0
HFD2_k127_914349_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001325 217.0
HFD2_k127_914349_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000003996 164.0
HFD2_k127_925786_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 312.0
HFD2_k127_925786_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000001698 183.0
HFD2_k127_925786_2 acetyltransferase - - - 0.0000000000000000000000000000000000000997 147.0
HFD2_k127_925786_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000002876 134.0
HFD2_k127_925786_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000002322 74.0
HFD2_k127_930390_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 612.0
HFD2_k127_930390_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 402.0
HFD2_k127_930390_10 PFAM AhpC TSA family K03564 - 1.11.1.15 0.000000000000000000000000924 106.0
HFD2_k127_930390_11 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000164 107.0
HFD2_k127_930390_12 SnoaL-like domain - - - 0.000000000004853 74.0
HFD2_k127_930390_13 Redoxin K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.0000000001828 65.0
HFD2_k127_930390_14 TonB-dependent receptor K16092 - - 0.0004857 43.0
HFD2_k127_930390_2 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 302.0
HFD2_k127_930390_3 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005177 303.0
HFD2_k127_930390_4 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000412 266.0
HFD2_k127_930390_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001392 254.0
HFD2_k127_930390_6 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000001523 207.0
HFD2_k127_930390_7 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000002075 197.0
HFD2_k127_930390_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000267 133.0
HFD2_k127_930390_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000001646 121.0
HFD2_k127_934219_0 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 362.0
HFD2_k127_934219_1 Dienelactone hydrolase family - - - 0.00000000000000000000001784 117.0
HFD2_k127_934219_2 Beta-lactamase - - - 0.00000000000006533 85.0
HFD2_k127_934219_3 Alpha beta hydrolase - - - 0.0000000002702 74.0
HFD2_k127_945742_0 Phospholipase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 369.0
HFD2_k127_945742_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000005733 243.0
HFD2_k127_945742_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000008698 55.0
HFD2_k127_950366_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.68e-249 775.0
HFD2_k127_950366_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.427e-237 744.0
HFD2_k127_950366_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000002703 78.0
HFD2_k127_950366_11 - - - - 0.000000007846 63.0
HFD2_k127_950366_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.075e-194 617.0
HFD2_k127_950366_3 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 347.0
HFD2_k127_950366_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 346.0
HFD2_k127_950366_5 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 329.0
HFD2_k127_950366_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 293.0
HFD2_k127_950366_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000004636 138.0
HFD2_k127_950366_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000001177 143.0
HFD2_k127_950366_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000001203 131.0
HFD2_k127_964346_0 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 489.0
HFD2_k127_964346_1 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 459.0
HFD2_k127_964346_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
HFD2_k127_964346_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
HFD2_k127_964346_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000004955 140.0
HFD2_k127_964346_6 - - - - 0.000000001576 69.0
HFD2_k127_975403_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
HFD2_k127_975403_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 314.0
HFD2_k127_975403_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001639 244.0
HFD2_k127_975403_3 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000008141 184.0
HFD2_k127_975403_4 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000005065 162.0
HFD2_k127_975403_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000001386 74.0
HFD2_k127_984575_0 PFAM FAD dependent oxidoreductase - - - 7.914e-202 640.0
HFD2_k127_984575_1 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 389.0
HFD2_k127_984575_2 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 311.0
HFD2_k127_984575_3 DinB family - - - 0.00000000000000000000000000000000000000000000000000000003681 205.0
HFD2_k127_984575_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000001093 176.0
HFD2_k127_984575_5 membrane - - - 0.00000000000000001307 97.0
HFD2_k127_984575_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000003094 75.0
HFD2_k127_987331_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.937e-228 721.0
HFD2_k127_987331_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 329.0
HFD2_k127_987331_2 Major Facilitator K08196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 314.0