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Overview

ID MAG01669
Name HFD2_bin.67
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family Ilumatobacteraceae
Genus JAENVT01
Species
Assembly information
Completeness (%) 86.09
Contamination (%) 3.64
GC content (%) 67.0
N50 (bp) 22,470
Genome size (bp) 3,843,311

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3531

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1009990_0 Peptidase family M41 - - - 5.031e-218 692.0
HFD2_k127_1009990_1 Thioesterase-like superfamily K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 336.0
HFD2_k127_1009990_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 308.0
HFD2_k127_1009990_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000209 213.0
HFD2_k127_1009990_5 chain release factor K15034 - - 0.00000000001073 78.0
HFD2_k127_1009990_6 Inner membrane component of T3SS, cytoplasmic domain K03466 - - 0.00000009114 62.0
HFD2_k127_1009990_7 - - - - 0.000005206 49.0
HFD2_k127_1101750_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 3.112e-251 784.0
HFD2_k127_1101750_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.142e-235 743.0
HFD2_k127_1101750_10 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 415.0
HFD2_k127_1101750_11 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 411.0
HFD2_k127_1101750_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 387.0
HFD2_k127_1101750_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 377.0
HFD2_k127_1101750_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 348.0
HFD2_k127_1101750_15 NADH pyrophosphatase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 335.0
HFD2_k127_1101750_16 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 330.0
HFD2_k127_1101750_17 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 274.0
HFD2_k127_1101750_18 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001019 256.0
HFD2_k127_1101750_19 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000001506 200.0
HFD2_k127_1101750_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.467e-212 672.0
HFD2_k127_1101750_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000002693 191.0
HFD2_k127_1101750_21 nuclease K01174,K07038 - 3.1.31.1 0.000000000000000000000000000000000000000000000006094 178.0
HFD2_k127_1101750_22 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000005579 156.0
HFD2_k127_1101750_23 - - - - 0.0000000000000000000000000001578 133.0
HFD2_k127_1101750_24 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000001332 122.0
HFD2_k127_1101750_25 Protein of unknown function, DUF488 - - - 0.00000000000000000000000002188 113.0
HFD2_k127_1101750_27 - - - - 0.0000000000000000001506 102.0
HFD2_k127_1101750_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 7.669e-211 666.0
HFD2_k127_1101750_30 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.000001692 57.0
HFD2_k127_1101750_4 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 573.0
HFD2_k127_1101750_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 557.0
HFD2_k127_1101750_6 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 515.0
HFD2_k127_1101750_7 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 494.0
HFD2_k127_1101750_8 GlcNAc-PI de-N-acetylase K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 460.0
HFD2_k127_1101750_9 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 427.0
HFD2_k127_1111294_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1119.0
HFD2_k127_1111294_1 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 451.0
HFD2_k127_1111294_10 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000006338 139.0
HFD2_k127_1111294_2 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 315.0
HFD2_k127_1111294_3 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
HFD2_k127_1111294_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007123 245.0
HFD2_k127_1111294_5 Evidence 5 No homology to any previously reported sequences K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000005589 248.0
HFD2_k127_1111294_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000006749 210.0
HFD2_k127_1111294_7 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000004088 199.0
HFD2_k127_1111294_8 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000002599 192.0
HFD2_k127_1111294_9 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000004744 193.0
HFD2_k127_1155403_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.661e-244 762.0
HFD2_k127_1155403_1 AMP-binding enzyme C-terminal domain - - - 5.773e-241 756.0
HFD2_k127_1155403_2 DEAD-like helicases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 537.0
HFD2_k127_1155403_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 312.0
HFD2_k127_1155403_4 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HFD2_k127_1155403_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000693 228.0
HFD2_k127_1155403_6 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000001791 169.0
HFD2_k127_1155403_7 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.000000004514 64.0
HFD2_k127_1177773_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1082.0
HFD2_k127_1177773_1 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 - 6.3.3.1,6.3.4.13 6.825e-297 936.0
HFD2_k127_1177773_10 Domain of unknown function (DUF4262) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004705 234.0
HFD2_k127_1177773_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000002655 225.0
HFD2_k127_1177773_12 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
HFD2_k127_1177773_13 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000002206 206.0
HFD2_k127_1177773_14 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000000000000000000000000005803 175.0
HFD2_k127_1177773_15 EamA-like transporter family - - - 0.000000000000000000001132 106.0
HFD2_k127_1177773_16 - - - - 0.000000000000000000001827 96.0
HFD2_k127_1177773_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.77e-251 782.0
HFD2_k127_1177773_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 2.11e-239 757.0
HFD2_k127_1177773_4 VWA domain containing CoxE-like protein K07161 - - 7.615e-203 634.0
HFD2_k127_1177773_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 593.0
HFD2_k127_1177773_6 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 537.0
HFD2_k127_1177773_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 466.0
HFD2_k127_1177773_8 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 418.0
HFD2_k127_1177773_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 305.0
HFD2_k127_1194833_0 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 519.0
HFD2_k127_1194833_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
HFD2_k127_1194833_10 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000006866 124.0
HFD2_k127_1194833_11 PFAM Sporulation and spore germination - - - 0.00000000000000007439 92.0
HFD2_k127_1194833_12 - - - - 0.00000001337 64.0
HFD2_k127_1194833_13 Cupredoxin-like domain - - - 0.0000001087 60.0
HFD2_k127_1194833_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 272.0
HFD2_k127_1194833_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 271.0
HFD2_k127_1194833_5 Peptidase C26 - - - 0.00000000000000000000000000000000000000000000000000000000001769 214.0
HFD2_k127_1194833_6 aminotransferase class I and II K00812,K10907,K14267 - 2.6.1.1,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000009661 208.0
HFD2_k127_1194833_7 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000005897 184.0
HFD2_k127_1194833_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000001812 177.0
HFD2_k127_1194833_9 Universal stress protein family - - - 0.000000000000000000000000000000000000000006185 166.0
HFD2_k127_1196755_0 HypF finger K04656 - - 3.14e-226 731.0
HFD2_k127_1196755_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 511.0
HFD2_k127_1196755_2 HupF/HypC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004674 258.0
HFD2_k127_1196755_3 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000001659 233.0
HFD2_k127_1196755_4 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000007883 179.0
HFD2_k127_1196755_5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000001437 105.0
HFD2_k127_1237013_0 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 323.0
HFD2_k127_1237013_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 314.0
HFD2_k127_1237013_2 Phosphatidylinositol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 316.0
HFD2_k127_1237013_3 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000001077 225.0
HFD2_k127_1237013_4 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000004052 211.0
HFD2_k127_1237013_5 alpha/beta hydrolase fold K01066 - - 0.0000000000582 64.0
HFD2_k127_1266494_0 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.0 1518.0
HFD2_k127_1266494_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000321 271.0
HFD2_k127_1269825_0 4Fe-4S dicluster domain - - - 0.0 1198.0
HFD2_k127_1269825_1 UDP-glucoronosyl and UDP-glucosyl transferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 612.0
HFD2_k127_1269825_10 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.00000000000000000000000000000000001173 156.0
HFD2_k127_1269825_11 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000006997 120.0
HFD2_k127_1269825_12 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000306 104.0
HFD2_k127_1269825_13 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000003806 91.0
HFD2_k127_1269825_14 Fibronectin type 3 domain - - - 0.0000000000001358 85.0
HFD2_k127_1269825_2 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 548.0
HFD2_k127_1269825_3 TIGRFAM luciferase family oxidoreductase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 432.0
HFD2_k127_1269825_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
HFD2_k127_1269825_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 325.0
HFD2_k127_1269825_6 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002529 273.0
HFD2_k127_1269825_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 257.0
HFD2_k127_1269825_8 COGs COG0673 dehydrogenase and related protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000002363 172.0
HFD2_k127_1269825_9 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.00000000000000000000000000000000000001658 155.0
HFD2_k127_1283144_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 7.662e-257 845.0
HFD2_k127_1283144_1 PFAM glycosyl transferase family 39 - - - 1.206e-224 743.0
HFD2_k127_1283144_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HFD2_k127_1283144_11 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 315.0
HFD2_k127_1283144_12 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008977 270.0
HFD2_k127_1283144_13 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
HFD2_k127_1283144_14 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000002812 181.0
HFD2_k127_1283144_15 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000006417 182.0
HFD2_k127_1283144_16 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000001059 160.0
HFD2_k127_1283144_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000001785 152.0
HFD2_k127_1283144_18 protein conserved in bacteria - - - 0.00000000000000000000000000000000004955 140.0
HFD2_k127_1283144_19 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.00000000000000000000000000000001937 132.0
HFD2_k127_1283144_2 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 507.0
HFD2_k127_1283144_20 - - - - 0.00000000000000000000000000000003584 130.0
HFD2_k127_1283144_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000001062 127.0
HFD2_k127_1283144_22 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000001414 107.0
HFD2_k127_1283144_23 Capsule synthesis protein K07282 - - 0.000000000000000007808 97.0
HFD2_k127_1283144_24 - - - - 0.000000000005467 70.0
HFD2_k127_1283144_25 - - - - 0.00006319 49.0
HFD2_k127_1283144_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 504.0
HFD2_k127_1283144_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 398.0
HFD2_k127_1283144_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 389.0
HFD2_k127_1283144_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 379.0
HFD2_k127_1283144_7 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 368.0
HFD2_k127_1283144_8 Peptidoglycan-binding domain 1 protein K01227,K01448,K03791,K13277,K17733 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 340.0
HFD2_k127_1283144_9 Glycosylase K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 334.0
HFD2_k127_132332_0 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 519.0
HFD2_k127_132332_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 377.0
HFD2_k127_132332_10 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000002942 178.0
HFD2_k127_132332_11 peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000002018 168.0
HFD2_k127_132332_12 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000009824 152.0
HFD2_k127_132332_14 Domain of unkown function (DUF1775) - - - 0.0000000000000000000321 103.0
HFD2_k127_132332_15 - - - - 0.0000000000000000001191 102.0
HFD2_k127_132332_16 - - - - 0.0000000000001226 79.0
HFD2_k127_132332_18 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000003401 60.0
HFD2_k127_132332_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 354.0
HFD2_k127_132332_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
HFD2_k127_132332_4 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 347.0
HFD2_k127_132332_5 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
HFD2_k127_132332_6 Copper resistance protein CopC K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000331 237.0
HFD2_k127_132332_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001115 226.0
HFD2_k127_132332_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000009854 204.0
HFD2_k127_132332_9 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000003026 196.0
HFD2_k127_1353543_0 PFAM 5'-nucleotidase, C-terminal domain K07004 - - 9.012e-248 812.0
HFD2_k127_1353543_1 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 3.983e-246 777.0
HFD2_k127_1353543_10 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 398.0
HFD2_k127_1353543_11 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 362.0
HFD2_k127_1353543_12 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 363.0
HFD2_k127_1353543_13 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 379.0
HFD2_k127_1353543_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 349.0
HFD2_k127_1353543_15 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 332.0
HFD2_k127_1353543_16 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000004285 236.0
HFD2_k127_1353543_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000009801 156.0
HFD2_k127_1353543_18 ATP-grasp domain - - - 0.000000000000000000000000000000003617 145.0
HFD2_k127_1353543_19 lysyltransferase activity K07027,K20468 - - 0.00000000000000000000001944 114.0
HFD2_k127_1353543_2 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 579.0
HFD2_k127_1353543_20 STAS domain K06378 - - 0.0003797 46.0
HFD2_k127_1353543_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 570.0
HFD2_k127_1353543_4 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 565.0
HFD2_k127_1353543_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 548.0
HFD2_k127_1353543_6 winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 517.0
HFD2_k127_1353543_7 cyclic nucleotide binding K15762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 491.0
HFD2_k127_1353543_8 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 417.0
HFD2_k127_1353543_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 409.0
HFD2_k127_1375153_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1488.0
HFD2_k127_1375153_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 541.0
HFD2_k127_1375153_2 Evidence 5 No homology to any previously reported sequences - - - 0.00001386 53.0
HFD2_k127_141012_0 PFAM Glycoside hydrolase, family 38 K01191 - 3.2.1.24 0.0 1025.0
HFD2_k127_141012_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 510.0
HFD2_k127_141012_2 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 443.0
HFD2_k127_141012_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
HFD2_k127_141012_4 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 315.0
HFD2_k127_141012_5 Nudix hydrolase K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.3.3.2 0.000000000000000000000000000001906 128.0
HFD2_k127_141012_7 Thiamine-binding protein - - - 0.0000000003455 64.0
HFD2_k127_1557247_0 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 5.418e-270 874.0
HFD2_k127_1557247_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.158e-220 691.0
HFD2_k127_1557247_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 478.0
HFD2_k127_1557247_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 451.0
HFD2_k127_1557247_4 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 320.0
HFD2_k127_1557247_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 305.0
HFD2_k127_1557247_6 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 298.0
HFD2_k127_1557247_7 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003184 267.0
HFD2_k127_1557247_8 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000005515 161.0
HFD2_k127_1557247_9 Histidine kinase - - - 0.00000000000000004215 87.0
HFD2_k127_1559182_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.001e-217 689.0
HFD2_k127_1559182_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.378e-214 683.0
HFD2_k127_1559182_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.995e-207 653.0
HFD2_k127_1559182_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 604.0
HFD2_k127_1559182_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 597.0
HFD2_k127_1559182_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000002427 104.0
HFD2_k127_1559182_6 Recombinase - - - 0.0003132 49.0
HFD2_k127_1560542_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 578.0
HFD2_k127_1560542_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 531.0
HFD2_k127_1560542_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 391.0
HFD2_k127_1560542_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 404.0
HFD2_k127_1560542_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 383.0
HFD2_k127_1560542_5 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000000000000000000001744 217.0
HFD2_k127_1560542_6 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000001954 154.0
HFD2_k127_1577837_0 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 1.22e-278 872.0
HFD2_k127_1577837_1 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 5.526e-267 830.0
HFD2_k127_1577837_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
HFD2_k127_1577837_11 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 300.0
HFD2_k127_1577837_12 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
HFD2_k127_1577837_13 PFAM Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002268 302.0
HFD2_k127_1577837_14 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
HFD2_k127_1577837_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000001854 234.0
HFD2_k127_1577837_16 Transcriptional regulator K05799 - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
HFD2_k127_1577837_17 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000001091 194.0
HFD2_k127_1577837_18 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000003226 194.0
HFD2_k127_1577837_19 COG0666 FOG Ankyrin repeat - - - 0.000000000000000000000000000000000002194 149.0
HFD2_k127_1577837_2 Ftsk_gamma K03466 - - 1.286e-206 668.0
HFD2_k127_1577837_20 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000005357 146.0
HFD2_k127_1577837_21 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000002132 130.0
HFD2_k127_1577837_22 acetyltransferase - - - 0.000000000000000000000000002059 120.0
HFD2_k127_1577837_23 acyl-L-homoserine-lactone lactonohydrolase activity K13075 - 3.1.1.81 0.00000000000000000000000002779 118.0
HFD2_k127_1577837_24 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000001271 97.0
HFD2_k127_1577837_26 60 kDa lysophospholipase K13278 GO:0003674,GO:0003824,GO:0003847,GO:0004067,GO:0004620,GO:0004622,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016053,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0016810,GO:0016811,GO:0019637,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0052689,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 3.1.1.47,3.1.1.5,3.5.1.1 0.000000009845 66.0
HFD2_k127_1577837_27 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.0000000351 58.0
HFD2_k127_1577837_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 599.0
HFD2_k127_1577837_4 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 511.0
HFD2_k127_1577837_5 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 473.0
HFD2_k127_1577837_6 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 453.0
HFD2_k127_1577837_7 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 429.0
HFD2_k127_1577837_8 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 418.0
HFD2_k127_1577837_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
HFD2_k127_1635856_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 439.0
HFD2_k127_1635856_1 decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 396.0
HFD2_k127_1635856_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 286.0
HFD2_k127_1635856_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000006635 171.0
HFD2_k127_1635856_4 Transcriptional regulator - - - 0.00000000000000000000001939 109.0
HFD2_k127_1642764_0 geranylgeranyl reductase activity K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 561.0
HFD2_k127_1642764_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 500.0
HFD2_k127_1642764_10 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001252 237.0
HFD2_k127_1642764_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000001793 231.0
HFD2_k127_1642764_12 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000001955 225.0
HFD2_k127_1642764_13 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000001251 174.0
HFD2_k127_1642764_14 electron transfer flavoprotein-ubiquinone oxidoreductase - - - 0.0000000000000000000000000000000000001712 159.0
HFD2_k127_1642764_15 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000002171 134.0
HFD2_k127_1642764_16 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000008165 126.0
HFD2_k127_1642764_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000001316 104.0
HFD2_k127_1642764_2 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 472.0
HFD2_k127_1642764_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 372.0
HFD2_k127_1642764_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 363.0
HFD2_k127_1642764_5 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
HFD2_k127_1642764_6 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 316.0
HFD2_k127_1642764_7 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 312.0
HFD2_k127_1642764_8 Alanine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 304.0
HFD2_k127_1642764_9 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
HFD2_k127_1764544_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.386e-262 813.0
HFD2_k127_1764544_1 Ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 7.757e-259 811.0
HFD2_k127_1764544_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 389.0
HFD2_k127_1764544_11 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
HFD2_k127_1764544_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001736 255.0
HFD2_k127_1764544_13 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001381 253.0
HFD2_k127_1764544_14 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000009787 233.0
HFD2_k127_1764544_15 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000002447 222.0
HFD2_k127_1764544_16 Initiation factor 2 subunit family - - - 0.000000000000000000000000000000000000000000000000000000005839 208.0
HFD2_k127_1764544_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003853 206.0
HFD2_k127_1764544_18 - - - - 0.000000000000000000000000000000000000000000000000000781 201.0
HFD2_k127_1764544_19 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000002117 154.0
HFD2_k127_1764544_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K15372 - 2.6.1.55,4.1.1.64 7.835e-225 706.0
HFD2_k127_1764544_20 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000006801 160.0
HFD2_k127_1764544_21 Methyltransferase domain - - - 0.0000000000000003195 88.0
HFD2_k127_1764544_3 Dihydropyrimidinase K01464 - 3.5.2.2 8.92e-220 692.0
HFD2_k127_1764544_4 ATP-dependent helicase K03579 - 3.6.4.13 2.726e-209 677.0
HFD2_k127_1764544_5 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 564.0
HFD2_k127_1764544_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 532.0
HFD2_k127_1764544_7 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 505.0
HFD2_k127_1764544_8 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 499.0
HFD2_k127_1764544_9 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 480.0
HFD2_k127_1819185_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 589.0
HFD2_k127_1819185_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 560.0
HFD2_k127_1819185_10 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 287.0
HFD2_k127_1819185_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004391 269.0
HFD2_k127_1819185_12 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001542 269.0
HFD2_k127_1819185_13 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003854 229.0
HFD2_k127_1819185_14 Sigma-70 region 3 K03090 - - 0.000000000000000000000000000000000000000000000000000003676 202.0
HFD2_k127_1819185_15 - - - - 0.000000000000000000000000000000000000001737 157.0
HFD2_k127_1819185_16 - - - - 0.00000000000000000000000000000000000003184 152.0
HFD2_k127_1819185_17 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.0000000000000000000000000000000000001627 151.0
HFD2_k127_1819185_18 ACT domain protein - - - 0.000000000000000000000000000000000000313 147.0
HFD2_k127_1819185_19 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000004059 115.0
HFD2_k127_1819185_2 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 491.0
HFD2_k127_1819185_21 sigma factor antagonist activity K04757 - 2.7.11.1 0.000002593 55.0
HFD2_k127_1819185_22 anti-sigma B factor K04757 - 2.7.11.1 0.00006187 52.0
HFD2_k127_1819185_3 cobalamin binding K20450 - 5.4.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 470.0
HFD2_k127_1819185_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
HFD2_k127_1819185_5 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 381.0
HFD2_k127_1819185_6 lipopolysaccharide transport K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 371.0
HFD2_k127_1819185_7 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 357.0
HFD2_k127_1819185_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 328.0
HFD2_k127_1819185_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 302.0
HFD2_k127_1838220_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.738e-286 885.0
HFD2_k127_1838220_1 PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 534.0
HFD2_k127_1838220_10 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000003132 198.0
HFD2_k127_1838220_11 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000007125 191.0
HFD2_k127_1838220_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000463 161.0
HFD2_k127_1838220_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000001009 102.0
HFD2_k127_1838220_16 single-stranded DNA binding K03111 - - 0.000000005324 64.0
HFD2_k127_1838220_18 Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase K07025 - - 0.000001267 53.0
HFD2_k127_1838220_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 541.0
HFD2_k127_1838220_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 440.0
HFD2_k127_1838220_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 413.0
HFD2_k127_1838220_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 327.0
HFD2_k127_1838220_6 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 310.0
HFD2_k127_1838220_7 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HFD2_k127_1838220_8 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009557 269.0
HFD2_k127_1838220_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003463 207.0
HFD2_k127_1841700_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.299e-207 672.0
HFD2_k127_1841700_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 610.0
HFD2_k127_1841700_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001248 252.0
HFD2_k127_1841700_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005294 253.0
HFD2_k127_1841700_12 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000006128 170.0
HFD2_k127_1841700_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000005054 160.0
HFD2_k127_1841700_14 cell cycle K05589,K13052 - - 0.0000000000000000000000001716 112.0
HFD2_k127_1841700_15 Evidence 5 No homology to any previously reported sequences - - - 0.00000000006321 67.0
HFD2_k127_1841700_16 antisigma factor binding K04749 - - 0.000000001178 65.0
HFD2_k127_1841700_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 443.0
HFD2_k127_1841700_3 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 438.0
HFD2_k127_1841700_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 438.0
HFD2_k127_1841700_5 sulfate ABC transporter K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 408.0
HFD2_k127_1841700_6 Binding-protein-dependent transport systems inner membrane component K02018,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
HFD2_k127_1841700_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
HFD2_k127_1841700_8 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 321.0
HFD2_k127_1841700_9 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 308.0
HFD2_k127_1844502_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.348e-297 928.0
HFD2_k127_1844502_1 Glycosyltransferase like family 2 - - - 2.767e-286 914.0
HFD2_k127_1844502_10 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 381.0
HFD2_k127_1844502_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 376.0
HFD2_k127_1844502_12 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
HFD2_k127_1844502_14 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 307.0
HFD2_k127_1844502_15 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
HFD2_k127_1844502_16 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 301.0
HFD2_k127_1844502_17 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000001098 230.0
HFD2_k127_1844502_18 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000002951 194.0
HFD2_k127_1844502_19 - - - - 0.00000000000000000000000000000000000000000000000001708 188.0
HFD2_k127_1844502_2 Psort location CytoplasmicMembrane, score - - - 4.53e-269 855.0
HFD2_k127_1844502_20 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000002038 188.0
HFD2_k127_1844502_21 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000003506 162.0
HFD2_k127_1844502_22 - - - - 0.00000000000000000000000000000000000000000166 167.0
HFD2_k127_1844502_23 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001334 146.0
HFD2_k127_1844502_24 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000001782 141.0
HFD2_k127_1844502_25 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000636 108.0
HFD2_k127_1844502_27 Enoyl-CoA hydratase isomerase family protein - - - 0.0005261 46.0
HFD2_k127_1844502_3 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 1.711e-238 742.0
HFD2_k127_1844502_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 2.124e-209 659.0
HFD2_k127_1844502_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 557.0
HFD2_k127_1844502_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 549.0
HFD2_k127_1844502_7 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 528.0
HFD2_k127_1844502_8 glycosyl transferase group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 470.0
HFD2_k127_1844502_9 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 410.0
HFD2_k127_1873720_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.297e-202 640.0
HFD2_k127_1873720_10 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 364.0
HFD2_k127_1873720_11 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 349.0
HFD2_k127_1873720_12 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 332.0
HFD2_k127_1873720_13 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 321.0
HFD2_k127_1873720_14 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 299.0
HFD2_k127_1873720_15 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HFD2_k127_1873720_16 Permeases of the drug metabolite transporter DMT superfamily K15269 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002347 249.0
HFD2_k127_1873720_17 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007625 258.0
HFD2_k127_1873720_18 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001634 244.0
HFD2_k127_1873720_19 Evidence 2b Function of strongly homologous gene K02282 - - 0.00000000000000000000000000000000000000000000000000000000000004071 237.0
HFD2_k127_1873720_2 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 524.0
HFD2_k127_1873720_20 Type ii secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000004735 244.0
HFD2_k127_1873720_21 stress protein (general stress protein 26) - - - 0.00000000000000000000000000000000000000000000000000000000002861 210.0
HFD2_k127_1873720_22 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000007555 203.0
HFD2_k127_1873720_23 Precorrin-8x methylmutase - - - 0.0000000000000000000000000000000000000000000000000000004424 204.0
HFD2_k127_1873720_24 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000004997 201.0
HFD2_k127_1873720_25 molybdopterin cofactor binding - - - 0.0000000000000000000000000000000000000000000000000004023 192.0
HFD2_k127_1873720_26 Type ii secretion system K12511 - - 0.000000000000000000000000000000000000000000000000008841 197.0
HFD2_k127_1873720_27 MarR family - - - 0.00000000000000000000000000000000000000000000009769 173.0
HFD2_k127_1873720_28 PFAM Short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000009139 166.0
HFD2_k127_1873720_29 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000001971 157.0
HFD2_k127_1873720_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 508.0
HFD2_k127_1873720_30 Pilus assembly protein K02279 - - 0.000000000000000000000000000000001425 140.0
HFD2_k127_1873720_31 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.00000000000000000000000002037 114.0
HFD2_k127_1873720_32 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000003627 111.0
HFD2_k127_1873720_33 GDSL-like Lipase/Acylhydrolase - - - 0.000000000006326 76.0
HFD2_k127_1873720_34 TadE-like protein - - - 0.00000001548 62.0
HFD2_k127_1873720_35 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.00000001672 60.0
HFD2_k127_1873720_36 Flp Fap pilin component K02651 - - 0.00000004477 57.0
HFD2_k127_1873720_37 pyridoxamine 5-phosphate - - - 0.0000002485 59.0
HFD2_k127_1873720_38 MT0933-like antitoxin protein - - - 0.000001234 53.0
HFD2_k127_1873720_39 KR domain K00059 - 1.1.1.100 0.0001189 51.0
HFD2_k127_1873720_4 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 470.0
HFD2_k127_1873720_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 445.0
HFD2_k127_1873720_6 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 436.0
HFD2_k127_1873720_7 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 421.0
HFD2_k127_1873720_8 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 402.0
HFD2_k127_1873720_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
HFD2_k127_1874902_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1671.0
HFD2_k127_1874902_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 542.0
HFD2_k127_1874902_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 490.0
HFD2_k127_1874902_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HFD2_k127_1874902_4 Guanylate kinase homologues. K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001794 257.0
HFD2_k127_1874902_5 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000005814 142.0
HFD2_k127_1874902_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000008583 115.0
HFD2_k127_1874902_7 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000009297 109.0
HFD2_k127_1874902_8 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000002924 69.0
HFD2_k127_1932803_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 317.0
HFD2_k127_1932803_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000001631 179.0
HFD2_k127_1932803_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000003518 178.0
HFD2_k127_1932803_3 Alpha beta - - - 0.0000000000000000000000000000000000001799 152.0
HFD2_k127_1942386_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 5.945e-248 778.0
HFD2_k127_1942386_1 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 567.0
HFD2_k127_1942386_10 MaoC like domain - - - 0.0000000000000000161 81.0
HFD2_k127_1942386_2 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 421.0
HFD2_k127_1942386_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 308.0
HFD2_k127_1942386_4 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 291.0
HFD2_k127_1942386_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000005978 233.0
HFD2_k127_1942386_6 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000015 204.0
HFD2_k127_1942386_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001992 198.0
HFD2_k127_1942386_8 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000004208 196.0
HFD2_k127_1942386_9 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000002176 166.0
HFD2_k127_1961793_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1168.0
HFD2_k127_1961793_1 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1034.0
HFD2_k127_1961793_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000005535 190.0
HFD2_k127_1961793_11 FtsX-like permease family - - - 0.000000000000000000000000000001942 140.0
HFD2_k127_1961793_12 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000008 107.0
HFD2_k127_1961793_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.253e-269 835.0
HFD2_k127_1961793_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 531.0
HFD2_k127_1961793_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 514.0
HFD2_k127_1961793_5 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 512.0
HFD2_k127_1961793_6 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 490.0
HFD2_k127_1961793_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 354.0
HFD2_k127_1961793_8 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 294.0
HFD2_k127_1961793_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HFD2_k127_1975471_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 612.0
HFD2_k127_1975471_1 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 428.0
HFD2_k127_1975471_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 305.0
HFD2_k127_1975471_3 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 303.0
HFD2_k127_1975471_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000003742 196.0
HFD2_k127_1975471_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000004995 178.0
HFD2_k127_1975471_6 PFAM Integrase, catalytic core K07482 - - 0.0000000003779 60.0
HFD2_k127_1987314_0 ABC transporter transmembrane region K06147 - - 2.229e-209 681.0
HFD2_k127_1987314_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 572.0
HFD2_k127_1987314_2 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 395.0
HFD2_k127_1987314_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 297.0
HFD2_k127_1987314_4 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
HFD2_k127_1987314_5 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000001577 165.0
HFD2_k127_2005620_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 580.0
HFD2_k127_2005620_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 512.0
HFD2_k127_2005620_2 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 406.0
HFD2_k127_2005620_3 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009488 357.0
HFD2_k127_2005620_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 357.0
HFD2_k127_2005620_5 deoxyribose-phosphate aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 310.0
HFD2_k127_2005620_6 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000002944 202.0
HFD2_k127_2029974_0 Glucose inhibited division protein A - - - 1.041e-230 723.0
HFD2_k127_2029974_1 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 458.0
HFD2_k127_2029974_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000004203 163.0
HFD2_k127_2029974_11 SnoaL-like domain - - - 0.000000000000000000000000000000000003999 150.0
HFD2_k127_2029974_12 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000005984 120.0
HFD2_k127_2029974_13 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000001621 109.0
HFD2_k127_2029974_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 404.0
HFD2_k127_2029974_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 395.0
HFD2_k127_2029974_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 353.0
HFD2_k127_2029974_5 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HFD2_k127_2029974_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 321.0
HFD2_k127_2029974_7 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005126 282.0
HFD2_k127_2029974_8 Binding-protein-dependent transport system inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005257 284.0
HFD2_k127_2029974_9 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000001429 197.0
HFD2_k127_2035980_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.173e-238 760.0
HFD2_k127_2035980_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.185e-227 709.0
HFD2_k127_2035980_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 475.0
HFD2_k127_2035980_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 450.0
HFD2_k127_2035980_4 peptidase K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 434.0
HFD2_k127_2035980_5 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 291.0
HFD2_k127_2035980_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000002117 136.0
HFD2_k127_2035980_7 SnoaL-like domain - - - 0.00000000000000000000609 106.0
HFD2_k127_2035980_8 light absorption - - - 0.0004573 52.0
HFD2_k127_2036008_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1450.0
HFD2_k127_2036008_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 2.781e-212 679.0
HFD2_k127_2036008_10 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 326.0
HFD2_k127_2036008_11 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 316.0
HFD2_k127_2036008_12 HhH-GPD superfamily base excision DNA repair protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002046 281.0
HFD2_k127_2036008_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 261.0
HFD2_k127_2036008_14 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000001235 231.0
HFD2_k127_2036008_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000003567 225.0
HFD2_k127_2036008_16 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000002088 210.0
HFD2_k127_2036008_17 Fungalysin metallopeptidase (M36) K01417 - - 0.0000000000000000000000000000000000000000000000000000000006345 226.0
HFD2_k127_2036008_18 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000006089 205.0
HFD2_k127_2036008_19 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000001232 168.0
HFD2_k127_2036008_2 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 553.0
HFD2_k127_2036008_20 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.0000000000000000000000000000000000001537 162.0
HFD2_k127_2036008_21 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000005578 131.0
HFD2_k127_2036008_22 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000006924 93.0
HFD2_k127_2036008_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 509.0
HFD2_k127_2036008_4 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 459.0
HFD2_k127_2036008_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 427.0
HFD2_k127_2036008_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 401.0
HFD2_k127_2036008_7 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 376.0
HFD2_k127_2036008_8 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 355.0
HFD2_k127_2036008_9 Myo-inositol 2-dehydrogenase K18652 - 1.1.1.361 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 340.0
HFD2_k127_207754_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 6.885e-280 882.0
HFD2_k127_207754_1 sulphate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 556.0
HFD2_k127_207754_10 regulatory protein, arsR - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000164 130.0
HFD2_k127_207754_11 Universal stress protein - - - 0.00000000000000000000000000002926 121.0
HFD2_k127_207754_12 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000002112 132.0
HFD2_k127_207754_13 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000002708 120.0
HFD2_k127_207754_14 ABC-2 family transporter protein K01992 - - 0.00000000000003577 83.0
HFD2_k127_207754_15 GYD domain - - - 0.0000000000000982 72.0
HFD2_k127_207754_16 Negative regulator of - - - 0.000001863 58.0
HFD2_k127_207754_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 473.0
HFD2_k127_207754_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 451.0
HFD2_k127_207754_4 Zn-dependent oxidoreductase, NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 421.0
HFD2_k127_207754_5 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 323.0
HFD2_k127_207754_6 ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 292.0
HFD2_k127_207754_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000263 278.0
HFD2_k127_207754_8 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K00058,K16843 - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000004305 218.0
HFD2_k127_207754_9 Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000001195 177.0
HFD2_k127_2105227_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 1.108e-231 725.0
HFD2_k127_2105227_1 Aminotransferase class I and II K14261 - - 7.311e-221 689.0
HFD2_k127_2105227_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 539.0
HFD2_k127_2105227_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003184 267.0
HFD2_k127_2105227_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001119 257.0
HFD2_k127_2105227_5 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000004707 172.0
HFD2_k127_2105227_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000009346 76.0
HFD2_k127_2141659_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 582.0
HFD2_k127_2141659_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 465.0
HFD2_k127_2141659_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000001657 230.0
HFD2_k127_2141659_3 - - - - 0.000000000000000000000000000000000000000000000000004581 186.0
HFD2_k127_2141659_4 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000001052 101.0
HFD2_k127_2141659_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00003872 46.0
HFD2_k127_2141659_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0001799 49.0
HFD2_k127_219946_0 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 5.412e-243 773.0
HFD2_k127_219946_1 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 402.0
HFD2_k127_219946_2 - - - - 0.00000000000000000000000000000000003547 137.0
HFD2_k127_221247_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 508.0
HFD2_k127_221247_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 343.0
HFD2_k127_221247_2 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
HFD2_k127_221247_3 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000756 203.0
HFD2_k127_221247_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000004011 173.0
HFD2_k127_221247_5 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000002898 138.0
HFD2_k127_221247_6 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000952 102.0
HFD2_k127_221247_7 - - - - 0.0000000000002711 81.0
HFD2_k127_221247_8 Dodecin K09165 - - 0.000001053 54.0
HFD2_k127_2253911_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 6.549e-311 959.0
HFD2_k127_2253911_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 342.0
HFD2_k127_2253911_2 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000117 261.0
HFD2_k127_2253911_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000003562 141.0
HFD2_k127_2265896_0 Protein synonym hydantoin utilization protein B K01474 - 3.5.2.14 1.87e-275 854.0
HFD2_k127_2265896_1 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.017e-208 682.0
HFD2_k127_2265896_2 Rieske 2Fe-2S K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 552.0
HFD2_k127_2265896_3 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 0.000000000000000000000000000000000001098 141.0
HFD2_k127_2278687_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 581.0
HFD2_k127_2278687_1 sulfate adenylyltransferase K00957 GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 451.0
HFD2_k127_2278687_10 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001898 269.0
HFD2_k127_2278687_11 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004611 270.0
HFD2_k127_2278687_12 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002716 272.0
HFD2_k127_2278687_13 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000001445 244.0
HFD2_k127_2278687_14 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002615 257.0
HFD2_k127_2278687_15 PFAM F5 8 type C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001531 255.0
HFD2_k127_2278687_16 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 247.0
HFD2_k127_2278687_17 Catalyzes the synthesis of activated sulfate K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000658 229.0
HFD2_k127_2278687_18 - - - - 0.00000000000000000000000000000000000000000000000000000000008929 217.0
HFD2_k127_2278687_19 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000003091 204.0
HFD2_k127_2278687_2 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 441.0
HFD2_k127_2278687_20 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000002122 201.0
HFD2_k127_2278687_21 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000006692 198.0
HFD2_k127_2278687_22 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000108 215.0
HFD2_k127_2278687_23 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000005179 177.0
HFD2_k127_2278687_24 - - - - 0.000000000000000000000000000000000000000000000007898 187.0
HFD2_k127_2278687_25 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000000000001797 170.0
HFD2_k127_2278687_26 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000001019 171.0
HFD2_k127_2278687_27 PFAM Glycosyl transferase family 2 K16870 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576 2.4.1.289 0.000000000000000000000000000000000000231 158.0
HFD2_k127_2278687_28 transcriptional regulator - - - 0.0000000000000000000000000000000005407 138.0
HFD2_k127_2278687_29 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000001472 140.0
HFD2_k127_2278687_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 421.0
HFD2_k127_2278687_30 Transcriptional regulator - - - 0.0000000000000000000000000000001468 137.0
HFD2_k127_2278687_31 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000003535 113.0
HFD2_k127_2278687_32 antisigma factor binding K04749 - - 0.000000000000000003183 87.0
HFD2_k127_2278687_33 diguanylate cyclase - - - 0.000000000000002366 86.0
HFD2_k127_2278687_34 AMP binding - - - 0.000000002353 65.0
HFD2_k127_2278687_35 transferase activity, transferring glycosyl groups K20276 - - 0.000000004586 71.0
HFD2_k127_2278687_36 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.0000005596 56.0
HFD2_k127_2278687_37 Sigma factor PP2C-like phosphatases - - - 0.0001282 51.0
HFD2_k127_2278687_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
HFD2_k127_2278687_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 374.0
HFD2_k127_2278687_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
HFD2_k127_2278687_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 294.0
HFD2_k127_2278687_8 belongs to the sigma-70 factor family K03090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
HFD2_k127_2278687_9 PFAM F5 8 type C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 285.0
HFD2_k127_2281061_0 Heat shock 70 kDa protein K04043 - - 0.0 1033.0
HFD2_k127_2281061_1 metallocarboxypeptidase activity - - - 4.54e-253 807.0
HFD2_k127_2281061_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000004075 168.0
HFD2_k127_2281061_11 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000000000003554 153.0
HFD2_k127_2281061_12 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000001301 148.0
HFD2_k127_2281061_13 Protein involved in monooxygenase activity, electron transporter activity, iron ion binding, electron transport, transport and aromatic compound catabolism - - - 0.00000000000000000000000000004785 121.0
HFD2_k127_2281061_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 400.0
HFD2_k127_2281061_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 400.0
HFD2_k127_2281061_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 358.0
HFD2_k127_2281061_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 340.0
HFD2_k127_2281061_6 sugar isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HFD2_k127_2281061_7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
HFD2_k127_2281061_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000482 202.0
HFD2_k127_2281061_9 - - - - 0.0000000000000000000000000000000000000000000000008686 186.0
HFD2_k127_2375805_0 PFAM Type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 537.0
HFD2_k127_2375805_1 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 501.0
HFD2_k127_2375805_2 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 453.0
HFD2_k127_2375805_3 cell adhesion involved in biofilm formation K13735,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000001026 261.0
HFD2_k127_2375805_4 Type ii secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000005387 233.0
HFD2_k127_2375805_5 Pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000005489 192.0
HFD2_k127_2375805_6 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000001916 173.0
HFD2_k127_2375805_7 Pilus assembly protein K02279 - - 0.0000000000000000000000000007117 123.0
HFD2_k127_2375805_8 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000001028 74.0
HFD2_k127_2393907_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 8.333e-215 671.0
HFD2_k127_2393907_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 343.0
HFD2_k127_2393907_2 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
HFD2_k127_2393907_3 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000001128 234.0
HFD2_k127_2393907_4 Lipoate-protein ligase - - - 0.000000000000000000000000000000000000006142 156.0
HFD2_k127_2393907_5 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000006221 139.0
HFD2_k127_2393907_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000001354 54.0
HFD2_k127_2393907_8 iron ion binding - - - 0.0003792 52.0
HFD2_k127_241365_0 Transcriptional regulator - - - 2.383e-288 910.0
HFD2_k127_241365_1 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 570.0
HFD2_k127_241365_2 - - - - 0.00000000000000000000000000000000000001442 147.0
HFD2_k127_241365_3 domain protein - - - 0.00000000000000009443 93.0
HFD2_k127_2567033_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 459.0
HFD2_k127_2567033_1 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000002137 206.0
HFD2_k127_2567033_2 dehydratase - - - 0.0000000000000716 81.0
HFD2_k127_2567033_3 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.000000000001011 74.0
HFD2_k127_2567033_5 Protein of unknown function (DUF4232) - - - 0.00004455 53.0
HFD2_k127_2669300_0 Salmonella virulence plasmid 65kDa B protein - - - 0.0 1504.0
HFD2_k127_2669300_1 ATPase, P-type K12952 - - 2.849e-221 710.0
HFD2_k127_2669300_10 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008051 279.0
HFD2_k127_2669300_11 ABC-type Na efflux pump, permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000007338 233.0
HFD2_k127_2669300_12 - - - - 0.0000000000000000000000000000000000000000000000000000000002178 211.0
HFD2_k127_2669300_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001081 219.0
HFD2_k127_2669300_14 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000006631 195.0
HFD2_k127_2669300_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000007291 179.0
HFD2_k127_2669300_16 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000008982 164.0
HFD2_k127_2669300_17 Histidine kinase - - - 0.00000000000000000000000000000000000000002989 167.0
HFD2_k127_2669300_18 Putative collagen-binding domain of a collagenase - - - 0.0000000000000000008026 102.0
HFD2_k127_2669300_19 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000007474 89.0
HFD2_k127_2669300_2 Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - 1.42e-197 638.0
HFD2_k127_2669300_20 Histidine kinase - - - 0.000000000000001183 89.0
HFD2_k127_2669300_21 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000001298 83.0
HFD2_k127_2669300_22 - - - - 0.00000000003851 73.0
HFD2_k127_2669300_23 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000663 50.0
HFD2_k127_2669300_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 580.0
HFD2_k127_2669300_4 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 435.0
HFD2_k127_2669300_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
HFD2_k127_2669300_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 361.0
HFD2_k127_2669300_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
HFD2_k127_2669300_8 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 306.0
HFD2_k127_2669300_9 a CheY-like receiver domain and - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002848 281.0
HFD2_k127_2690123_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.324e-265 824.0
HFD2_k127_2690123_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 392.0
HFD2_k127_2690123_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 341.0
HFD2_k127_2690123_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000003954 245.0
HFD2_k127_2690123_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000001565 225.0
HFD2_k127_2690123_5 - - - - 0.0000000000000000000000001835 111.0
HFD2_k127_2690123_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000002561 113.0
HFD2_k127_2727855_0 Epoxide hydrolase N terminus K21159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 513.0
HFD2_k127_2727855_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 468.0
HFD2_k127_2727855_10 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000003214 128.0
HFD2_k127_2727855_11 PAP2 superfamily - - - 0.000000000000000000000000005878 123.0
HFD2_k127_2727855_12 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000002255 68.0
HFD2_k127_2727855_2 AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 466.0
HFD2_k127_2727855_3 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 376.0
HFD2_k127_2727855_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
HFD2_k127_2727855_5 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006051 270.0
HFD2_k127_2727855_6 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000004068 196.0
HFD2_k127_2727855_7 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000102 196.0
HFD2_k127_2727855_8 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000001796 166.0
HFD2_k127_2727855_9 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000001467 171.0
HFD2_k127_2738962_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1757.0
HFD2_k127_2738962_1 Protein of unknown function, DUF255 K06888 - - 8.798e-271 850.0
HFD2_k127_2738962_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 295.0
HFD2_k127_2738962_11 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000001814 269.0
HFD2_k127_2738962_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 237.0
HFD2_k127_2738962_13 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
HFD2_k127_2738962_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000406 213.0
HFD2_k127_2738962_15 Protein of unknown function (DUF2587) - - - 0.0000000000000000000000000000000000000000000000000004446 189.0
HFD2_k127_2738962_16 Nitroreductase family - - - 0.000000000000000000000000000000000000001327 163.0
HFD2_k127_2738962_2 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.637e-229 725.0
HFD2_k127_2738962_3 tRNA synthetases class I (C) catalytic domain K15526 - 6.3.1.13 1.358e-199 629.0
HFD2_k127_2738962_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 449.0
HFD2_k127_2738962_5 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HFD2_k127_2738962_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 414.0
HFD2_k127_2738962_7 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 365.0
HFD2_k127_2738962_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 347.0
HFD2_k127_2738962_9 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 315.0
HFD2_k127_2761339_0 Acyl transferase domain - - - 0.0 1785.0
HFD2_k127_2761339_1 acyl-CoA dehydrogenase activity - - - 8.57e-233 734.0
HFD2_k127_2761339_2 Protein of unknown function (DUF3376) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004971 284.0
HFD2_k127_2761339_4 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000000002593 134.0
HFD2_k127_2805076_0 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006695 269.0
HFD2_k127_2805076_1 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000002215 217.0
HFD2_k127_2805076_2 - - - - 0.0000000000000000000000000000000000001257 162.0
HFD2_k127_2805076_3 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000001748 142.0
HFD2_k127_2805076_4 Glycosyl transferase, family 2 K20444 - - 0.0004837 53.0
HFD2_k127_284757_0 FAD dependent oxidoreductase central domain - - - 0.0 1320.0
HFD2_k127_284757_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1031.0
HFD2_k127_284757_10 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 394.0
HFD2_k127_284757_11 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 383.0
HFD2_k127_284757_12 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 355.0
HFD2_k127_284757_13 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 319.0
HFD2_k127_284757_14 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 296.0
HFD2_k127_284757_15 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 302.0
HFD2_k127_284757_16 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008769 279.0
HFD2_k127_284757_17 HD phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 262.0
HFD2_k127_284757_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001572 270.0
HFD2_k127_284757_19 Inosine-uridine preferring nucleoside hydrolase K01240 - 3.2.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000302 257.0
HFD2_k127_284757_2 Bacterial transcriptional activator domain - - - 1.827e-284 907.0
HFD2_k127_284757_20 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000006019 245.0
HFD2_k127_284757_21 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
HFD2_k127_284757_22 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000008774 198.0
HFD2_k127_284757_23 homocysteine K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000966 191.0
HFD2_k127_284757_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000001409 179.0
HFD2_k127_284757_25 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000005707 178.0
HFD2_k127_284757_26 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000002287 154.0
HFD2_k127_284757_27 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000002716 154.0
HFD2_k127_284757_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000002743 151.0
HFD2_k127_284757_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000006382 141.0
HFD2_k127_284757_3 Pfam Sulfatase - - - 6.348e-210 671.0
HFD2_k127_284757_30 peroxiredoxin activity K03386,K03564 - 1.11.1.15 0.0000000000000000000000001324 109.0
HFD2_k127_284757_31 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000571 106.0
HFD2_k127_284757_32 NlpC/P60 family - - - 0.0000000000000000000007953 108.0
HFD2_k127_284757_33 FAD binding domain - - - 0.000000000005178 67.0
HFD2_k127_284757_34 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000001198 65.0
HFD2_k127_284757_35 EamA-like transporter family - - - 0.0000001381 63.0
HFD2_k127_284757_36 luxR family - - - 0.0000009587 55.0
HFD2_k127_284757_4 Rieske [2Fe-2S] domain K15762 - - 9.774e-206 655.0
HFD2_k127_284757_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 539.0
HFD2_k127_284757_6 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 523.0
HFD2_k127_284757_7 Belongs to the arginase family K12255 - 3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 483.0
HFD2_k127_284757_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 486.0
HFD2_k127_284757_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 425.0
HFD2_k127_288282_0 glycine cleavage T protein (aminomethyl transferase) K19191 - 1.5.3.19 0.0 1114.0
HFD2_k127_288282_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 362.0
HFD2_k127_288282_2 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 361.0
HFD2_k127_288282_3 GYD domain - - - 0.0000000000000000000000199 109.0
HFD2_k127_2887740_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 1.17e-259 807.0
HFD2_k127_2887740_1 helicase activity - - - 1.738e-219 690.0
HFD2_k127_2887740_2 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 353.0
HFD2_k127_2887740_3 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000008508 183.0
HFD2_k127_293825_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2308.0
HFD2_k127_293825_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.443e-260 807.0
HFD2_k127_293825_10 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000343 162.0
HFD2_k127_293825_11 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000001418 142.0
HFD2_k127_293825_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000003647 94.0
HFD2_k127_293825_13 LysM domain - - - 0.000000000000000004053 92.0
HFD2_k127_293825_2 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 518.0
HFD2_k127_293825_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 499.0
HFD2_k127_293825_4 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 482.0
HFD2_k127_293825_5 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 469.0
HFD2_k127_293825_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 387.0
HFD2_k127_293825_7 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 329.0
HFD2_k127_293825_8 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
HFD2_k127_293825_9 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000007592 201.0
HFD2_k127_2975649_0 ABC transporter transmembrane region K06147 - - 8.408e-237 749.0
HFD2_k127_2975649_1 ABC transporter transmembrane region K06147 - - 1.166e-223 708.0
HFD2_k127_2975649_10 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
HFD2_k127_2975649_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001926 287.0
HFD2_k127_2975649_12 myo-inosose-2 dehydratase activity K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
HFD2_k127_2975649_13 - - - - 0.00000000000000000000000000000000000000000000000000002211 196.0
HFD2_k127_2975649_14 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000002667 189.0
HFD2_k127_2975649_15 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000002142 182.0
HFD2_k127_2975649_16 nUDIX hydrolase - - - 0.00000000000000000000000000000000000000005267 161.0
HFD2_k127_2975649_17 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000009418 140.0
HFD2_k127_2975649_19 arsenate reductase (glutaredoxin) activity K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000001241 132.0
HFD2_k127_2975649_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03520 - 1.2.5.3 3.5e-199 647.0
HFD2_k127_2975649_20 Transglycosylase associated protein - - - 0.00000000000000000000000000004356 118.0
HFD2_k127_2975649_21 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000006633 116.0
HFD2_k127_2975649_22 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.00000000000000000000004658 104.0
HFD2_k127_2975649_23 SnoaL-like domain - - - 0.0000000000000000000005656 102.0
HFD2_k127_2975649_24 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000001198 100.0
HFD2_k127_2975649_25 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000001281 93.0
HFD2_k127_2975649_27 Phosphotransferase enzyme family - - - 0.0000000000005984 79.0
HFD2_k127_2975649_28 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000002364 71.0
HFD2_k127_2975649_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 575.0
HFD2_k127_2975649_4 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 507.0
HFD2_k127_2975649_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 505.0
HFD2_k127_2975649_6 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 468.0
HFD2_k127_2975649_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 354.0
HFD2_k127_2975649_8 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 334.0
HFD2_k127_2975649_9 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 303.0
HFD2_k127_2985415_0 AMP-binding enzyme C-terminal domain K00666 - - 1.976e-254 793.0
HFD2_k127_2985415_1 PFAM AMP-dependent synthetase and ligase K00666 - - 5.812e-226 711.0
HFD2_k127_2985415_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 458.0
HFD2_k127_2985415_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 392.0
HFD2_k127_2985415_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 370.0
HFD2_k127_2985415_5 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000146 184.0
HFD2_k127_2985415_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000001848 127.0
HFD2_k127_2998832_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 7.366e-259 809.0
HFD2_k127_2998832_1 tRNA-splicing ligase RtcB K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 614.0
HFD2_k127_2998832_10 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 373.0
HFD2_k127_2998832_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 352.0
HFD2_k127_2998832_12 Belongs to the ABC transporter superfamily K02031,K15583 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 347.0
HFD2_k127_2998832_13 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 341.0
HFD2_k127_2998832_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
HFD2_k127_2998832_15 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
HFD2_k127_2998832_16 Domain of unknown function (DUF4130 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001593 210.0
HFD2_k127_2998832_17 Pfam Isochorismatase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000001083 205.0
HFD2_k127_2998832_18 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000003435 216.0
HFD2_k127_2998832_19 YjbR - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
HFD2_k127_2998832_2 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 604.0
HFD2_k127_2998832_20 Polysaccharide deacetylase K01448,K22278 - 3.5.1.104,3.5.1.28 0.00000000000000000000000000000000000000000000000000003801 208.0
HFD2_k127_2998832_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000003641 179.0
HFD2_k127_2998832_22 Belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000000000003134 167.0
HFD2_k127_2998832_23 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002305 163.0
HFD2_k127_2998832_24 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000009077 164.0
HFD2_k127_2998832_25 transport, permease protein K01992 - - 0.00000000000000000000000000000000000171 150.0
HFD2_k127_2998832_26 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002992 113.0
HFD2_k127_2998832_27 - - - - 0.0000000000000000000004531 98.0
HFD2_k127_2998832_28 Universal stress protein family - - - 0.000000000000006346 88.0
HFD2_k127_2998832_29 2TM domain - - - 0.00000000000007929 75.0
HFD2_k127_2998832_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 551.0
HFD2_k127_2998832_30 COG1960 Acyl-CoA dehydrogenases - - - 0.0002283 53.0
HFD2_k127_2998832_4 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 525.0
HFD2_k127_2998832_5 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 504.0
HFD2_k127_2998832_6 malic protein domain protein K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 487.0
HFD2_k127_2998832_7 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 435.0
HFD2_k127_2998832_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 404.0
HFD2_k127_2998832_9 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HFD2_k127_3104606_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.246e-284 893.0
HFD2_k127_3104606_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 511.0
HFD2_k127_3104606_10 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 0.000002205 50.0
HFD2_k127_3104606_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 489.0
HFD2_k127_3104606_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 358.0
HFD2_k127_3104606_4 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 323.0
HFD2_k127_3104606_5 purine-nucleoside phosphorylase K00772,K03784 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000001497 247.0
HFD2_k127_3104606_6 Pfam SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000002669 223.0
HFD2_k127_3104606_7 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000001063 171.0
HFD2_k127_3104606_9 - - - - 0.000000000000000000000000007129 126.0
HFD2_k127_3112465_0 von Willebrand factor (vWF) type A domain - - - 4.12e-321 993.0
HFD2_k127_3112465_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 581.0
HFD2_k127_3112465_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 332.0
HFD2_k127_3112465_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HFD2_k127_3112465_4 Belongs to the GcvT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001653 239.0
HFD2_k127_3112465_5 gntR family - - - 0.0000000000000000000000000000006721 133.0
HFD2_k127_3112465_6 beta-glucosidase activity K00067,K05350 - 1.1.1.133,3.2.1.21 0.0000000000000000000000000000009111 135.0
HFD2_k127_3112465_7 sporulation resulting in formation of a cellular spore K21449 - - 0.0000000000000000000004989 103.0
HFD2_k127_3112465_8 Pkd domain containing protein - - - 0.0001326 51.0
HFD2_k127_3133879_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 596.0
HFD2_k127_3133879_1 dna ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 476.0
HFD2_k127_3133879_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 434.0
HFD2_k127_3133879_3 response to copper ion K07156,K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 422.0
HFD2_k127_3133879_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000005787 158.0
HFD2_k127_3133879_5 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000714 114.0
HFD2_k127_3139154_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1436.0
HFD2_k127_3139154_1 acyl-CoA dehydrogenase - - - 2.655e-222 695.0
HFD2_k127_3139154_10 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 345.0
HFD2_k127_3139154_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 331.0
HFD2_k127_3139154_12 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 296.0
HFD2_k127_3139154_13 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003161 300.0
HFD2_k127_3139154_14 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000458 243.0
HFD2_k127_3139154_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000478 214.0
HFD2_k127_3139154_16 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000006775 166.0
HFD2_k127_3139154_18 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000006125 60.0
HFD2_k127_3139154_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 1.323e-216 676.0
HFD2_k127_3139154_3 Ammonium Transporter Family K03320 - - 6.13e-196 624.0
HFD2_k127_3139154_4 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 567.0
HFD2_k127_3139154_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 450.0
HFD2_k127_3139154_6 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 452.0
HFD2_k127_3139154_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 411.0
HFD2_k127_3139154_8 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 361.0
HFD2_k127_3139154_9 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 351.0
HFD2_k127_3149671_0 belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 548.0
HFD2_k127_3149671_1 Cupredoxin-like domain K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 414.0
HFD2_k127_3149671_10 hemerythrin HHE cation binding domain - - - 0.00000000000000005763 87.0
HFD2_k127_3149671_11 Fungalysin metallopeptidase (M36) - - - 0.000001683 63.0
HFD2_k127_3149671_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005932 280.0
HFD2_k127_3149671_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001247 251.0
HFD2_k127_3149671_5 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
HFD2_k127_3149671_6 YCII-related domain - - - 0.0000000000000000000000000000000000000000003988 157.0
HFD2_k127_3149671_7 Copper resistance protein D - - - 0.0000000000000000000000000000000000000001629 154.0
HFD2_k127_3149671_8 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000002688 158.0
HFD2_k127_3149671_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.00000000000000000000005547 117.0
HFD2_k127_3170586_0 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 534.0
HFD2_k127_3170586_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 547.0
HFD2_k127_3170586_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002053 168.0
HFD2_k127_3170586_11 YCII-related domain - - - 0.000000000000000000000000000000000000000003658 161.0
HFD2_k127_3170586_12 Belongs to the peptidase S8 family K01173 - - 0.00000000000000000000000000000000000002759 163.0
HFD2_k127_3170586_13 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000002653 139.0
HFD2_k127_3170586_14 lipolytic protein G-D-S-L family - - - 0.00000000000000000000002303 116.0
HFD2_k127_3170586_15 Phage integrase family - - - 0.0000000006754 70.0
HFD2_k127_3170586_16 - - - - 0.000000001077 60.0
HFD2_k127_3170586_2 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 392.0
HFD2_k127_3170586_3 PFAM glycosidase, PH1107-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 390.0
HFD2_k127_3170586_4 Predicted Permease Membrane Region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 327.0
HFD2_k127_3170586_5 resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 320.0
HFD2_k127_3170586_6 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000019 255.0
HFD2_k127_3170586_7 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000006844 225.0
HFD2_k127_3170586_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000082 220.0
HFD2_k127_3170586_9 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000005075 177.0
HFD2_k127_3170965_0 Succinyl-CoA ligase like flavodoxin domain - - - 9.787e-230 741.0
HFD2_k127_3170965_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 295.0
HFD2_k127_3170965_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
HFD2_k127_3170965_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006105 229.0
HFD2_k127_3170965_4 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000002059 139.0
HFD2_k127_3170965_5 Sigma-70 region 2 - - - 0.00000000000000000000000000002986 125.0
HFD2_k127_3170965_6 AMP binding - - - 0.000000743 59.0
HFD2_k127_317931_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.333e-314 973.0
HFD2_k127_317931_1 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 511.0
HFD2_k127_317931_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 323.0
HFD2_k127_317931_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 312.0
HFD2_k127_317931_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
HFD2_k127_317931_13 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
HFD2_k127_317931_14 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
HFD2_k127_317931_15 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
HFD2_k127_317931_16 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000002427 235.0
HFD2_k127_317931_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000007722 214.0
HFD2_k127_317931_18 PFAM class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000005781 209.0
HFD2_k127_317931_19 of HD superfamily K07023 - - 0.00000000000000000000000000000000000000000000000371 188.0
HFD2_k127_317931_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
HFD2_k127_317931_20 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000001199 187.0
HFD2_k127_317931_21 - - - - 0.00000000000000000000000000000000000000004675 156.0
HFD2_k127_317931_22 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000126 171.0
HFD2_k127_317931_23 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000005895 151.0
HFD2_k127_317931_24 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000009587 139.0
HFD2_k127_317931_25 DNA-binding protein - - - 0.000000000000000000000000000001645 132.0
HFD2_k127_317931_26 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000000000000002389 92.0
HFD2_k127_317931_27 - - - - 0.000000000005728 76.0
HFD2_k127_317931_29 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000002163 67.0
HFD2_k127_317931_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 436.0
HFD2_k127_317931_30 Exonuclease VII small subunit K03602 - 3.1.11.6 0.000004332 56.0
HFD2_k127_317931_31 LysM domain - - - 0.000008939 58.0
HFD2_k127_317931_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 430.0
HFD2_k127_317931_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 423.0
HFD2_k127_317931_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 441.0
HFD2_k127_317931_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 394.0
HFD2_k127_317931_8 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
HFD2_k127_317931_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
HFD2_k127_3246434_0 HD domain - - - 9.545e-217 685.0
HFD2_k127_3246434_1 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 617.0
HFD2_k127_3246434_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
HFD2_k127_3246434_11 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000000000000000000000000000719 205.0
HFD2_k127_3246434_12 - - - - 0.0000000000000000000000000000000000000000006042 167.0
HFD2_k127_3246434_13 SnoaL-like domain - - - 0.0000000000000000000000000000000004332 135.0
HFD2_k127_3246434_14 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000001849 133.0
HFD2_k127_3246434_15 Secreted repeat of unknown function - - - 0.0000000000000000000000000005992 122.0
HFD2_k127_3246434_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00002609 49.0
HFD2_k127_3246434_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 584.0
HFD2_k127_3246434_3 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 507.0
HFD2_k127_3246434_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 504.0
HFD2_k127_3246434_5 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 441.0
HFD2_k127_3246434_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 429.0
HFD2_k127_3246434_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 332.0
HFD2_k127_3246434_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005898 259.0
HFD2_k127_3246434_9 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 243.0
HFD2_k127_3319922_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 482.0
HFD2_k127_3319922_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 316.0
HFD2_k127_3319922_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
HFD2_k127_3319922_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000003783 130.0
HFD2_k127_3360951_0 Branched-chain amino acid transport system / permease component K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 437.0
HFD2_k127_3360951_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
HFD2_k127_3360951_2 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
HFD2_k127_3360951_3 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 311.0
HFD2_k127_3360951_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
HFD2_k127_3360951_5 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000000005116 199.0
HFD2_k127_3524092_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 1.984e-281 872.0
HFD2_k127_3524092_1 ABC transporter - - - 5.69e-241 755.0
HFD2_k127_3524092_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000001974 139.0
HFD2_k127_3524092_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000005543 102.0
HFD2_k127_3524092_2 glycine radical enzyme, YjjI family - - - 6.126e-221 695.0
HFD2_k127_3524092_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 350.0
HFD2_k127_3524092_5 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006532 246.0
HFD2_k127_3524092_6 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000004303 199.0
HFD2_k127_3524092_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000006572 169.0
HFD2_k127_3524092_8 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000005045 166.0
HFD2_k127_3524092_9 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000822 168.0
HFD2_k127_3564751_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 3.603e-273 851.0
HFD2_k127_3564751_1 Peptidase dimerisation domain - - - 1.734e-206 655.0
HFD2_k127_3564751_10 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 400.0
HFD2_k127_3564751_11 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 366.0
HFD2_k127_3564751_12 transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 344.0
HFD2_k127_3564751_13 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 351.0
HFD2_k127_3564751_14 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 326.0
HFD2_k127_3564751_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003007 290.0
HFD2_k127_3564751_17 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
HFD2_k127_3564751_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000002785 185.0
HFD2_k127_3564751_19 Protein of unknown function (DUF448) K07742 - - 0.0000000003384 66.0
HFD2_k127_3564751_2 Participates in both transcription termination and antitermination K02600 - - 1.641e-194 621.0
HFD2_k127_3564751_20 - - - - 0.00003556 54.0
HFD2_k127_3564751_3 geranylgeranyl reductase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 514.0
HFD2_k127_3564751_4 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 486.0
HFD2_k127_3564751_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 483.0
HFD2_k127_3564751_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 477.0
HFD2_k127_3564751_7 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 417.0
HFD2_k127_3564751_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 422.0
HFD2_k127_3564751_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
HFD2_k127_3568329_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.511e-269 840.0
HFD2_k127_3568329_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 510.0
HFD2_k127_3568329_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 424.0
HFD2_k127_3568329_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 259.0
HFD2_k127_3568329_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000009149 152.0
HFD2_k127_3568329_5 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000001326 137.0
HFD2_k127_3568329_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000008703 117.0
HFD2_k127_363310_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 325.0
HFD2_k127_363310_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001378 239.0
HFD2_k127_363310_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000008366 211.0
HFD2_k127_363310_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000004945 184.0
HFD2_k127_363310_4 FAD binding domain - - - 0.000000000009767 77.0
HFD2_k127_363310_5 Transcriptional regulatory protein, C terminal - - - 0.000000001866 63.0
HFD2_k127_3642274_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.504e-214 683.0
HFD2_k127_3642274_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.43e-212 669.0
HFD2_k127_3642274_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 352.0
HFD2_k127_3642274_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 319.0
HFD2_k127_3642274_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 320.0
HFD2_k127_3642274_13 N-acetyltransferase - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009607,GO:0009987,GO:0010941,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0034069,GO:0035821,GO:0040007,GO:0042802,GO:0043067,GO:0043207,GO:0044003,GO:0044068,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044248,GO:0044403,GO:0044419,GO:0044531,GO:0048518,GO:0048583,GO:0048584,GO:0050727,GO:0050729,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052032,GO:0052035,GO:0052040,GO:0052164,GO:0052167,GO:0052173,GO:0052200,GO:0052248,GO:0052255,GO:0052256,GO:0052259,GO:0052303,GO:0052306,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052564,GO:0052567,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 312.0
HFD2_k127_3642274_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 304.0
HFD2_k127_3642274_15 Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HFD2_k127_3642274_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
HFD2_k127_3642274_17 Esterase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HFD2_k127_3642274_18 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000002077 264.0
HFD2_k127_3642274_19 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000009101 243.0
HFD2_k127_3642274_2 Peptidase dimerisation domain - - - 6.129e-196 627.0
HFD2_k127_3642274_20 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002265 236.0
HFD2_k127_3642274_21 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.0000000000000000000000000000000000000000000000000007318 185.0
HFD2_k127_3642274_22 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000001129 185.0
HFD2_k127_3642274_23 DinB superfamily - - - 0.000000000000000000000000000000000000000000000005693 181.0
HFD2_k127_3642274_24 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000002133 176.0
HFD2_k127_3642274_25 YjbR - - - 0.00000000000000000000000000000000000000000004078 163.0
HFD2_k127_3642274_26 Acyl-CoA dehydrogenase, C-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000001706 142.0
HFD2_k127_3642274_27 YCII-related domain - - - 0.00000000000000000000000000000000005523 145.0
HFD2_k127_3642274_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001668 134.0
HFD2_k127_3642274_29 FR47-like protein - - - 0.000000000000001286 91.0
HFD2_k127_3642274_3 CoA binding domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 526.0
HFD2_k127_3642274_30 Zn-dependent oxidoreductase, NADPH quinone reductase - - - 0.0000000007151 59.0
HFD2_k127_3642274_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 473.0
HFD2_k127_3642274_5 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 454.0
HFD2_k127_3642274_6 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 445.0
HFD2_k127_3642274_7 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 410.0
HFD2_k127_3642274_8 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 409.0
HFD2_k127_3642274_9 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
HFD2_k127_3684026_0 AAA domain - - - 5.533e-301 938.0
HFD2_k127_3684026_1 Glycosyl transferase 4-like domain - - - 9.247e-216 676.0
HFD2_k127_3684026_10 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 332.0
HFD2_k127_3684026_11 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 332.0
HFD2_k127_3684026_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HFD2_k127_3684026_13 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
HFD2_k127_3684026_14 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001141 278.0
HFD2_k127_3684026_15 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000004226 231.0
HFD2_k127_3684026_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000006733 188.0
HFD2_k127_3684026_17 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000008304 179.0
HFD2_k127_3684026_18 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000005275 123.0
HFD2_k127_3684026_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 2.62e-205 651.0
HFD2_k127_3684026_20 - - - - 0.000000001499 64.0
HFD2_k127_3684026_3 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 501.0
HFD2_k127_3684026_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 496.0
HFD2_k127_3684026_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
HFD2_k127_3684026_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 456.0
HFD2_k127_3684026_7 Thioesterase-like superfamily K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 424.0
HFD2_k127_3684026_8 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 432.0
HFD2_k127_3684026_9 DEAD-like helicases superfamily K03724,K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 333.0
HFD2_k127_3698889_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 494.0
HFD2_k127_3698889_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 473.0
HFD2_k127_3698889_10 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000001128 234.0
HFD2_k127_3698889_11 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000008787 215.0
HFD2_k127_3698889_12 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.0000000000000000000000000000007475 127.0
HFD2_k127_3698889_14 PFAM Sporulation and spore germination - - - 0.00000001146 65.0
HFD2_k127_3698889_2 ABC transporter K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 442.0
HFD2_k127_3698889_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 424.0
HFD2_k127_3698889_4 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 442.0
HFD2_k127_3698889_5 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 409.0
HFD2_k127_3698889_6 transport, permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 338.0
HFD2_k127_3698889_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000007369 266.0
HFD2_k127_3698889_8 Inositol monophosphatase family K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000001009 241.0
HFD2_k127_3698889_9 transport, permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
HFD2_k127_3722147_0 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 571.0
HFD2_k127_3722147_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 471.0
HFD2_k127_3722147_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000002167 198.0
HFD2_k127_3722147_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000004539 168.0
HFD2_k127_3722147_4 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000009568 151.0
HFD2_k127_3722147_5 - - - - 0.000000000000000000000000000000000000001185 160.0
HFD2_k127_3722147_6 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000001096 130.0
HFD2_k127_3744161_0 B3/4 domain K01890 - 6.1.1.20 1.321e-306 957.0
HFD2_k127_3744161_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 428.0
HFD2_k127_3744161_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000001621 209.0
HFD2_k127_3744161_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000006326 210.0
HFD2_k127_3744161_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000001015 173.0
HFD2_k127_3744161_13 - - - - 0.0000000000000000000000000004315 117.0
HFD2_k127_3744161_14 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.000000000000000000000002874 107.0
HFD2_k127_3744161_15 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000001604 108.0
HFD2_k127_3744161_16 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006552 94.0
HFD2_k127_3744161_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 421.0
HFD2_k127_3744161_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
HFD2_k127_3744161_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 320.0
HFD2_k127_3744161_5 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 302.0
HFD2_k127_3744161_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002541 280.0
HFD2_k127_3744161_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
HFD2_k127_3744161_8 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000005207 224.0
HFD2_k127_3744161_9 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
HFD2_k127_377855_0 Domain of unknown function (DUF3367) K16648 - - 0.0 1132.0
HFD2_k127_377855_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 6.682e-207 664.0
HFD2_k127_377855_10 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 371.0
HFD2_k127_377855_11 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 345.0
HFD2_k127_377855_12 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
HFD2_k127_377855_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
HFD2_k127_377855_14 UbiA prenyltransferase family K14136 - 2.4.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 326.0
HFD2_k127_377855_15 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
HFD2_k127_377855_16 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 295.0
HFD2_k127_377855_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009821 289.0
HFD2_k127_377855_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
HFD2_k127_377855_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007233 285.0
HFD2_k127_377855_2 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 1.998e-203 682.0
HFD2_k127_377855_20 PFAM short chain dehydrogenase K16652 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000007685 252.0
HFD2_k127_377855_21 Evidence 5 No homology to any previously reported sequences K14340 - - 0.000000000000000000000000000000000000000000000000000000000005251 228.0
HFD2_k127_377855_22 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000177 179.0
HFD2_k127_377855_23 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000002214 167.0
HFD2_k127_377855_24 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000001188 154.0
HFD2_k127_377855_25 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000003065 142.0
HFD2_k127_377855_26 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000002524 115.0
HFD2_k127_377855_27 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000007833 121.0
HFD2_k127_377855_28 Acyltransferase family - - - 0.00000000000000001359 98.0
HFD2_k127_377855_3 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 508.0
HFD2_k127_377855_4 D-arabinono-1,4-lactone oxidase K16653 - 1.1.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 509.0
HFD2_k127_377855_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 497.0
HFD2_k127_377855_6 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
HFD2_k127_377855_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 458.0
HFD2_k127_377855_8 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 399.0
HFD2_k127_377855_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 398.0
HFD2_k127_3793345_0 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 312.0
HFD2_k127_3793345_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
HFD2_k127_3793345_2 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000538 285.0
HFD2_k127_3793345_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 272.0
HFD2_k127_3793345_4 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
HFD2_k127_3793345_5 Protein of unknown function with PCYCGC motif - - - 0.00000000005973 70.0
HFD2_k127_3793345_6 membrane protein (DUF2078) K08982 - - 0.000000005864 62.0
HFD2_k127_3803593_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 9.057e-249 803.0
HFD2_k127_3803593_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 5.609e-206 650.0
HFD2_k127_3803593_10 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 447.0
HFD2_k127_3803593_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 422.0
HFD2_k127_3803593_12 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 409.0
HFD2_k127_3803593_13 Protein involved in transcription factor activity, ATP binding, drug transporter activity, ATPase activity, metal ion binding, regulation of transcription, DNA-dependent, drug transport, metal ion transport, defense response to pathogen and response to antibiotic K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 384.0
HFD2_k127_3803593_14 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 356.0
HFD2_k127_3803593_15 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
HFD2_k127_3803593_16 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 348.0
HFD2_k127_3803593_17 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 348.0
HFD2_k127_3803593_18 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 291.0
HFD2_k127_3803593_19 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 289.0
HFD2_k127_3803593_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 2.438e-196 640.0
HFD2_k127_3803593_20 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001658 280.0
HFD2_k127_3803593_21 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007089 271.0
HFD2_k127_3803593_22 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
HFD2_k127_3803593_23 phage tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002007 236.0
HFD2_k127_3803593_24 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000006038 222.0
HFD2_k127_3803593_25 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000253 227.0
HFD2_k127_3803593_26 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000001222 224.0
HFD2_k127_3803593_27 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000004548 214.0
HFD2_k127_3803593_28 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
HFD2_k127_3803593_29 dehydratase - - - 0.00000000000000000000000000000000000000000000000000132 188.0
HFD2_k127_3803593_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 629.0
HFD2_k127_3803593_30 Golgi phosphoprotein 3 (GPP34) - - - 0.000000000000000000000000000000000000000000000000004188 197.0
HFD2_k127_3803593_31 PFAM MarR family - - - 0.000000000000000000000000000000000000000000000001328 178.0
HFD2_k127_3803593_32 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.00000000000000000000000000000000000000000001516 168.0
HFD2_k127_3803593_33 lactoylglutathione lyase activity K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.000000000000000000000000000000000000000003153 163.0
HFD2_k127_3803593_34 peroxiredoxin activity - - - 0.000000000000000000000000000000000001045 149.0
HFD2_k127_3803593_35 SnoaL-like domain - - - 0.0000000000000000000000000000000001735 147.0
HFD2_k127_3803593_36 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000001938 139.0
HFD2_k127_3803593_37 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000002038 106.0
HFD2_k127_3803593_38 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000001248 96.0
HFD2_k127_3803593_39 Thioesterase-like superfamily - - - 0.000000000001975 67.0
HFD2_k127_3803593_4 Domain of unknown function (DUF4162) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 525.0
HFD2_k127_3803593_40 GYD domain - - - 0.000000000009522 69.0
HFD2_k127_3803593_41 PFAM FAD linked oxidase - - - 0.000000001762 58.0
HFD2_k127_3803593_42 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.00000361 53.0
HFD2_k127_3803593_43 Short chain dehydrogenase K00059 - 1.1.1.100 0.00005974 51.0
HFD2_k127_3803593_44 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.00007463 45.0
HFD2_k127_3803593_45 AAA ATPase domain - - - 0.0001619 49.0
HFD2_k127_3803593_5 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 548.0
HFD2_k127_3803593_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 516.0
HFD2_k127_3803593_7 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 521.0
HFD2_k127_3803593_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 471.0
HFD2_k127_3803593_9 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 444.0
HFD2_k127_3810546_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 563.0
HFD2_k127_3810546_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 541.0
HFD2_k127_3810546_10 Short-chain dehydrogenase reductase sdr K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000000000000000000000006986 128.0
HFD2_k127_3810546_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 436.0
HFD2_k127_3810546_3 hydratase K01617,K02509 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 309.0
HFD2_k127_3810546_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
HFD2_k127_3810546_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003144 268.0
HFD2_k127_3810546_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000724 177.0
HFD2_k127_3810546_7 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.000000000000000000000000000000000000000000001335 168.0
HFD2_k127_3810546_8 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000001735 170.0
HFD2_k127_3810546_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000001287 172.0
HFD2_k127_3818926_0 hydrogenase expression formation protein HypD K04654 - - 1.231e-209 655.0
HFD2_k127_3818926_1 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 486.0
HFD2_k127_3818926_2 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 367.0
HFD2_k127_3818926_3 Diacylglycerol kinase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000002896 211.0
HFD2_k127_3818926_4 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000000005254 180.0
HFD2_k127_3818926_5 Ankyrin repeat - - - 0.000000000000000000000000000000000001982 144.0
HFD2_k127_3818926_6 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000001978 129.0
HFD2_k127_3818926_7 hydrogenase maturation factor K04653 - - 0.000000000000000000000001388 107.0
HFD2_k127_3818926_8 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000007214 91.0
HFD2_k127_3818926_9 Belongs to the UPF0312 family - - - 0.00002651 53.0
HFD2_k127_3889025_0 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 390.0
HFD2_k127_3889025_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 385.0
HFD2_k127_3889025_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 372.0
HFD2_k127_3889025_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000004303 249.0
HFD2_k127_3889025_4 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000003878 229.0
HFD2_k127_3889025_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000004415 177.0
HFD2_k127_3889025_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000002009 88.0
HFD2_k127_3889025_7 EamA-like transporter family - - - 0.0000000000000007881 91.0
HFD2_k127_3999368_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1317.0
HFD2_k127_3999368_1 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 1.047e-196 623.0
HFD2_k127_3999368_10 Ester cyclase - - - 0.00000000000000278 81.0
HFD2_k127_3999368_11 SWIM zinc finger - - - 0.00000000003119 73.0
HFD2_k127_3999368_12 - - - - 0.0000000001975 68.0
HFD2_k127_3999368_13 HNH endonuclease - - - 0.0000008032 55.0
HFD2_k127_3999368_2 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 630.0
HFD2_k127_3999368_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 582.0
HFD2_k127_3999368_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 571.0
HFD2_k127_3999368_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 316.0
HFD2_k127_3999368_6 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000257 282.0
HFD2_k127_3999368_7 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 261.0
HFD2_k127_3999368_8 - - - - 0.000000000000000000000000000000000000206 144.0
HFD2_k127_3999368_9 - - - - 0.00000000000000000000000000000004848 136.0
HFD2_k127_4111053_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 605.0
HFD2_k127_4111053_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 400.0
HFD2_k127_4111053_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
HFD2_k127_4111053_3 PIN domain K07064 - - 0.0000000000000000000000000000000000000000002297 167.0
HFD2_k127_4111053_4 PFAM acyltransferase 3 - - - 0.0000000000000004454 83.0
HFD2_k127_4111053_5 positive regulation of growth - - - 0.0000000000005929 78.0
HFD2_k127_4171645_0 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 562.0
HFD2_k127_4171645_1 Phage late control gene D protein (GPD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 567.0
HFD2_k127_4171645_2 - - - - 0.00000000000000000000000000000000000000000000000000001111 190.0
HFD2_k127_4171645_3 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000000002221 181.0
HFD2_k127_4171645_5 positive regulation of growth rate - - - 0.00000000000000000000000000000000000000004849 160.0
HFD2_k127_4171645_6 phage tail protein - - - 0.0000000000000000000000000002526 126.0
HFD2_k127_4171645_7 Domain of unknown function (DUF4157) - - - 0.0000000000000000000001941 114.0
HFD2_k127_4171645_8 - - - - 0.00000000008849 63.0
HFD2_k127_4192326_0 CoA binding domain - - - 1.9e-322 1001.0
HFD2_k127_4192326_1 Proteasomal ATPase OB/ID domain K13527 - - 3.425e-300 927.0
HFD2_k127_4192326_10 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 284.0
HFD2_k127_4192326_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HFD2_k127_4192326_12 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004338 282.0
HFD2_k127_4192326_13 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006604 278.0
HFD2_k127_4192326_14 Allophanate hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001147 262.0
HFD2_k127_4192326_15 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
HFD2_k127_4192326_16 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000006661 220.0
HFD2_k127_4192326_17 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001982 211.0
HFD2_k127_4192326_18 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000001769 211.0
HFD2_k127_4192326_19 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000007893 211.0
HFD2_k127_4192326_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 7.803e-277 854.0
HFD2_k127_4192326_20 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000001164 176.0
HFD2_k127_4192326_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000006366 159.0
HFD2_k127_4192326_22 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000000000000003817 158.0
HFD2_k127_4192326_23 lipid kinase activity - - - 0.0000000000000000000000000000000002418 140.0
HFD2_k127_4192326_24 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.000000000000000000000006867 106.0
HFD2_k127_4192326_25 - - - - 0.00000000000000000000007969 106.0
HFD2_k127_4192326_27 SnoaL-like domain - - - 0.00000000000000000004293 96.0
HFD2_k127_4192326_28 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.4.53 0.00000000000000000008214 103.0
HFD2_k127_4192326_29 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.0000000000000000004283 88.0
HFD2_k127_4192326_3 Pup-ligase protein K20814 - 3.5.1.119 2.416e-241 753.0
HFD2_k127_4192326_30 - - - - 0.00000000000000005347 88.0
HFD2_k127_4192326_31 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000002451 70.0
HFD2_k127_4192326_4 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 3.132e-236 760.0
HFD2_k127_4192326_5 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 396.0
HFD2_k127_4192326_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 385.0
HFD2_k127_4192326_7 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
HFD2_k127_4192326_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
HFD2_k127_4192326_9 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 322.0
HFD2_k127_4243207_0 AAA domain - - - 1.794e-244 772.0
HFD2_k127_4243207_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 7.148e-200 640.0
HFD2_k127_4243207_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004934 278.0
HFD2_k127_4243207_11 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004328 251.0
HFD2_k127_4243207_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000000000000000000005647 229.0
HFD2_k127_4243207_13 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000001408 218.0
HFD2_k127_4243207_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000454 209.0
HFD2_k127_4243207_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001799 165.0
HFD2_k127_4243207_16 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000001676 162.0
HFD2_k127_4243207_17 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000002128 151.0
HFD2_k127_4243207_18 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000009051 154.0
HFD2_k127_4243207_19 Mycofactocin system - - - 0.00000000000000000000153 96.0
HFD2_k127_4243207_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 599.0
HFD2_k127_4243207_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 517.0
HFD2_k127_4243207_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 448.0
HFD2_k127_4243207_5 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 389.0
HFD2_k127_4243207_6 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
HFD2_k127_4243207_7 Glycosyl hydrolases family 18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 367.0
HFD2_k127_4243207_8 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 330.0
HFD2_k127_4243207_9 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001624 287.0
HFD2_k127_4246286_0 Flavin containing amine oxidoreductase - - - 2.676e-245 787.0
HFD2_k127_4246286_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 467.0
HFD2_k127_4246286_10 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 307.0
HFD2_k127_4246286_11 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 293.0
HFD2_k127_4246286_12 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HFD2_k127_4246286_13 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005319 237.0
HFD2_k127_4246286_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
HFD2_k127_4246286_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000004136 224.0
HFD2_k127_4246286_16 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000005905 186.0
HFD2_k127_4246286_17 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000000000153 189.0
HFD2_k127_4246286_18 Methyltransferase domain - - - 0.000000000000000000000000000000001516 139.0
HFD2_k127_4246286_19 Major facilitator superfamily - - - 0.000000000000000000000000000002689 136.0
HFD2_k127_4246286_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 444.0
HFD2_k127_4246286_20 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000008918 113.0
HFD2_k127_4246286_3 ribosomal rna small subunit methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 424.0
HFD2_k127_4246286_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 406.0
HFD2_k127_4246286_5 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 378.0
HFD2_k127_4246286_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 393.0
HFD2_k127_4246286_7 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 367.0
HFD2_k127_4246286_8 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 357.0
HFD2_k127_4246286_9 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 352.0
HFD2_k127_4349905_0 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 7.359e-216 697.0
HFD2_k127_4349905_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 486.0
HFD2_k127_4349905_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 468.0
HFD2_k127_4349905_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 458.0
HFD2_k127_4349905_4 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 411.0
HFD2_k127_4349905_5 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
HFD2_k127_4349905_6 transcriptional regulator - - - 0.000000000000000000000000000006272 123.0
HFD2_k127_4349905_7 Methylmuconolactone methyl-isomerase - - - 0.000000004388 64.0
HFD2_k127_4373020_0 Evidence 4 Homologs of previously reported genes of - - - 1.393e-199 633.0
HFD2_k127_4373020_1 Peptidase, S9A B C family, catalytic domain protein K01354 - 3.4.21.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 587.0
HFD2_k127_4373020_2 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 380.0
HFD2_k127_4373020_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 345.0
HFD2_k127_4373020_4 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 325.0
HFD2_k127_4373020_5 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 321.0
HFD2_k127_4373020_6 electron transfer activity K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000000000015 126.0
HFD2_k127_4373020_7 - - - - 0.00000000000000000000000000003038 134.0
HFD2_k127_4373020_8 Methylamine utilisation protein MauE - - - 0.00000000000000000000006257 102.0
HFD2_k127_4373020_9 - - - - 0.0000000000001549 73.0
HFD2_k127_4389823_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1113.0
HFD2_k127_4389823_1 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 7.4e-322 1007.0
HFD2_k127_4389823_10 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 561.0
HFD2_k127_4389823_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 539.0
HFD2_k127_4389823_12 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 531.0
HFD2_k127_4389823_13 Penicillin binding protein transpeptidase domain K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 534.0
HFD2_k127_4389823_14 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 492.0
HFD2_k127_4389823_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 462.0
HFD2_k127_4389823_16 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 443.0
HFD2_k127_4389823_17 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
HFD2_k127_4389823_18 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 447.0
HFD2_k127_4389823_19 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 372.0
HFD2_k127_4389823_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.266e-300 934.0
HFD2_k127_4389823_20 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 351.0
HFD2_k127_4389823_21 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 336.0
HFD2_k127_4389823_22 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 327.0
HFD2_k127_4389823_23 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
HFD2_k127_4389823_24 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
HFD2_k127_4389823_25 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 304.0
HFD2_k127_4389823_26 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002495 291.0
HFD2_k127_4389823_27 Protein of unknown function (DUF2662) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000163 280.0
HFD2_k127_4389823_28 ParB-like nuclease domain K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001427 278.0
HFD2_k127_4389823_29 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
HFD2_k127_4389823_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 3.634e-259 813.0
HFD2_k127_4389823_30 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003617 257.0
HFD2_k127_4389823_31 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000009689 257.0
HFD2_k127_4389823_32 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002083 251.0
HFD2_k127_4389823_33 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008851 213.0
HFD2_k127_4389823_34 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000006659 190.0
HFD2_k127_4389823_35 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001762 193.0
HFD2_k127_4389823_37 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000006446 171.0
HFD2_k127_4389823_38 membrane - - - 0.00000000000000000000000000000000000000001365 162.0
HFD2_k127_4389823_39 Forkhead associated domain - - - 0.00000000000000000000000000000000000000025 159.0
HFD2_k127_4389823_4 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 621.0
HFD2_k127_4389823_40 - - - - 0.000000000000000000000000000000000000005151 150.0
HFD2_k127_4389823_41 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 - 2.7.8.24 0.00000000000000000000000000000000000003271 153.0
HFD2_k127_4389823_42 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000002874 147.0
HFD2_k127_4389823_43 DNA-binding transcription factor activity K18996 - - 0.00000000000000000000000000000001333 131.0
HFD2_k127_4389823_44 - - - - 0.0000000000000000000000000000001035 128.0
HFD2_k127_4389823_46 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000008026 119.0
HFD2_k127_4389823_47 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000005085 96.0
HFD2_k127_4389823_48 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000000000000002611 94.0
HFD2_k127_4389823_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 614.0
HFD2_k127_4389823_50 Ribosomal protein L34 K02914 - - 0.00000000009469 72.0
HFD2_k127_4389823_51 Endonuclease Exonuclease phosphatase - - - 0.000000000753 70.0
HFD2_k127_4389823_52 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.0000007102 58.0
HFD2_k127_4389823_54 protoporphyrinogen oxidase activity - - - 0.0000127 51.0
HFD2_k127_4389823_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 589.0
HFD2_k127_4389823_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
HFD2_k127_4389823_8 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 593.0
HFD2_k127_4389823_9 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 561.0
HFD2_k127_4390701_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 253.0
HFD2_k127_4390701_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001246 253.0
HFD2_k127_4390701_2 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.000000000000000000000000000000000001472 158.0
HFD2_k127_4390701_4 - - - - 0.00002236 57.0
HFD2_k127_4437463_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 464.0
HFD2_k127_4437463_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 418.0
HFD2_k127_4437463_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00001208 48.0
HFD2_k127_4437463_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 371.0
HFD2_k127_4437463_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 344.0
HFD2_k127_4437463_4 aminotransferase class I and II K00812,K10907,K14267 - 2.6.1.1,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
HFD2_k127_4437463_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000941 265.0
HFD2_k127_4437463_6 Pyridoxamine 5'-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000002019 249.0
HFD2_k127_4437463_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000002194 168.0
HFD2_k127_4437463_8 - - - - 0.0000000000000000000000000000000000000004317 158.0
HFD2_k127_4437463_9 Acetyltransferase, GNAT K06977 - - 0.0000000000000000000000000000000002208 136.0
HFD2_k127_4440906_0 penicillin-binding protein - - - 2.47e-250 793.0
HFD2_k127_4440906_1 ABC transporter transmembrane region K06147 - - 4.948e-240 764.0
HFD2_k127_4440906_10 Cold shock protein K03704 - - 0.0000000000000000000003101 98.0
HFD2_k127_4440906_12 Phage integrase family - - - 0.000000000000000002593 88.0
HFD2_k127_4440906_13 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000003462 93.0
HFD2_k127_4440906_15 STAS domain K04749 - - 0.00000000000005213 76.0
HFD2_k127_4440906_16 - - - - 0.000000000001193 73.0
HFD2_k127_4440906_17 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000002746 56.0
HFD2_k127_4440906_18 - - - - 0.00000007623 61.0
HFD2_k127_4440906_19 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000745 54.0
HFD2_k127_4440906_2 ABC transporter transmembrane region K06147 - - 5.02e-235 760.0
HFD2_k127_4440906_20 STAS domain K04749 - - 0.0004003 48.0
HFD2_k127_4440906_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 370.0
HFD2_k127_4440906_4 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.0000000000000000000000000000000000000000000002126 173.0
HFD2_k127_4440906_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000008148 161.0
HFD2_k127_4440906_6 - - - - 0.0000000000000000000000000000000000000401 149.0
HFD2_k127_4440906_8 - K07164,K22391 - 3.5.4.16 0.00000000000000000000000001753 117.0
HFD2_k127_4440906_9 - - - - 0.0000000000000000000000009633 104.0
HFD2_k127_4454758_0 ABC transporter - - - 1.028e-301 932.0
HFD2_k127_4454758_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.178e-246 764.0
HFD2_k127_4454758_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 348.0
HFD2_k127_4454758_11 inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 321.0
HFD2_k127_4454758_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 318.0
HFD2_k127_4454758_13 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 306.0
HFD2_k127_4454758_14 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
HFD2_k127_4454758_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
HFD2_k127_4454758_16 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
HFD2_k127_4454758_17 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007408 220.0
HFD2_k127_4454758_18 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000004067 201.0
HFD2_k127_4454758_19 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000239 161.0
HFD2_k127_4454758_2 ABC1 family - - - 2.995e-239 752.0
HFD2_k127_4454758_20 amine dehydrogenase activity - - - 0.000006591 53.0
HFD2_k127_4454758_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.038e-209 655.0
HFD2_k127_4454758_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 511.0
HFD2_k127_4454758_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 444.0
HFD2_k127_4454758_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 407.0
HFD2_k127_4454758_7 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 389.0
HFD2_k127_4454758_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 370.0
HFD2_k127_4454758_9 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HFD2_k127_4461499_0 Protein synonym peptidase M K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 484.0
HFD2_k127_4461499_1 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 455.0
HFD2_k127_4461499_2 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 313.0
HFD2_k127_4461499_3 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
HFD2_k127_4461499_4 hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004586 265.0
HFD2_k127_4461499_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
HFD2_k127_4461499_6 HTH domain - - - 0.000000000000000000000000000000000000000000005407 166.0
HFD2_k127_4503409_0 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 1.008e-255 800.0
HFD2_k127_4503409_1 Protein of unknown function (DUF512) - - - 1.835e-213 673.0
HFD2_k127_4503409_10 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004101 279.0
HFD2_k127_4503409_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004131 286.0
HFD2_k127_4503409_12 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005412 286.0
HFD2_k127_4503409_13 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006491 262.0
HFD2_k127_4503409_14 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001983 266.0
HFD2_k127_4503409_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000000007062 235.0
HFD2_k127_4503409_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000019 231.0
HFD2_k127_4503409_17 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000004838 224.0
HFD2_k127_4503409_18 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000002144 235.0
HFD2_k127_4503409_19 Histidine triad (Hit) protein K02503 - - 0.0000000000000000000000000000000000000000000000000000005335 196.0
HFD2_k127_4503409_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.095e-204 642.0
HFD2_k127_4503409_20 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000001658 203.0
HFD2_k127_4503409_22 and related - - - 0.0000000000000000000000000000000000000000000001702 180.0
HFD2_k127_4503409_23 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000001018 136.0
HFD2_k127_4503409_24 copper resistance K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001605 124.0
HFD2_k127_4503409_25 CHASE - - - 0.00000000000000000000000000004444 132.0
HFD2_k127_4503409_26 Transglutaminase-like superfamily - - - 0.000000000000000000000000000132 130.0
HFD2_k127_4503409_29 - - - - 0.0000000009336 72.0
HFD2_k127_4503409_3 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 541.0
HFD2_k127_4503409_31 AAA ATPase domain - - - 0.000001508 61.0
HFD2_k127_4503409_32 - - - - 0.00004899 56.0
HFD2_k127_4503409_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 526.0
HFD2_k127_4503409_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 494.0
HFD2_k127_4503409_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 389.0
HFD2_k127_4503409_7 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 349.0
HFD2_k127_4503409_8 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 302.0
HFD2_k127_4503409_9 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000019 275.0
HFD2_k127_4534309_0 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.0 1389.0
HFD2_k127_4534309_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.872e-273 848.0
HFD2_k127_4534309_10 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 445.0
HFD2_k127_4534309_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 443.0
HFD2_k127_4534309_12 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
HFD2_k127_4534309_13 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 424.0
HFD2_k127_4534309_14 ABC transporter substrate-binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 434.0
HFD2_k127_4534309_15 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 396.0
HFD2_k127_4534309_16 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 384.0
HFD2_k127_4534309_17 PFAM Glycosyl transferases group 1 K03867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 359.0
HFD2_k127_4534309_18 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 361.0
HFD2_k127_4534309_19 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 317.0
HFD2_k127_4534309_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.662e-241 755.0
HFD2_k127_4534309_20 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 317.0
HFD2_k127_4534309_21 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 319.0
HFD2_k127_4534309_22 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
HFD2_k127_4534309_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 309.0
HFD2_k127_4534309_24 TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
HFD2_k127_4534309_25 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005337 282.0
HFD2_k127_4534309_26 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001785 285.0
HFD2_k127_4534309_27 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005752 287.0
HFD2_k127_4534309_28 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002989 276.0
HFD2_k127_4534309_29 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
HFD2_k127_4534309_3 synthetase K18688 - 6.2.1.42 1.278e-232 732.0
HFD2_k127_4534309_30 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001242 262.0
HFD2_k127_4534309_31 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000002483 242.0
HFD2_k127_4534309_32 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
HFD2_k127_4534309_33 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002162 204.0
HFD2_k127_4534309_34 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000003234 198.0
HFD2_k127_4534309_35 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000000000009861 182.0
HFD2_k127_4534309_36 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000008402 178.0
HFD2_k127_4534309_37 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000001555 175.0
HFD2_k127_4534309_38 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000001356 175.0
HFD2_k127_4534309_39 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000002936 169.0
HFD2_k127_4534309_4 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 7.094e-220 699.0
HFD2_k127_4534309_40 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000001558 149.0
HFD2_k127_4534309_42 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000004705 109.0
HFD2_k127_4534309_43 Prokaryotic phospholipase A2 - - - 0.0000000000000000004295 93.0
HFD2_k127_4534309_44 Protein conserved in bacteria - - - 0.000000004168 67.0
HFD2_k127_4534309_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 3.519e-211 664.0
HFD2_k127_4534309_6 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 524.0
HFD2_k127_4534309_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 510.0
HFD2_k127_4534309_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 505.0
HFD2_k127_4534309_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 474.0
HFD2_k127_4565174_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.406e-306 960.0
HFD2_k127_4565174_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.124e-276 870.0
HFD2_k127_4565174_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 419.0
HFD2_k127_4565174_11 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 323.0
HFD2_k127_4565174_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003491 285.0
HFD2_k127_4565174_13 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006635 284.0
HFD2_k127_4565174_14 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
HFD2_k127_4565174_16 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000002504 194.0
HFD2_k127_4565174_17 nUDIX hydrolase K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000007157 178.0
HFD2_k127_4565174_18 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07667 - - 0.000000000000000000000000000000000001429 148.0
HFD2_k127_4565174_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.848e-254 822.0
HFD2_k127_4565174_20 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000004415 124.0
HFD2_k127_4565174_21 Domain of unknown function (DUF4118) - - - 0.00000000000000000003445 100.0
HFD2_k127_4565174_23 Psort location Cytoplasmic, score - - - 0.00000000000001513 84.0
HFD2_k127_4565174_24 - - - - 0.00000000000003619 83.0
HFD2_k127_4565174_26 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000631 64.0
HFD2_k127_4565174_27 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000002327 52.0
HFD2_k127_4565174_28 - - - - 0.0004424 45.0
HFD2_k127_4565174_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.108e-253 793.0
HFD2_k127_4565174_4 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 1.384e-240 769.0
HFD2_k127_4565174_5 MgsA AAA+ ATPase C terminal K07478 - - 3.02e-208 655.0
HFD2_k127_4565174_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.252e-200 634.0
HFD2_k127_4565174_7 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 605.0
HFD2_k127_4565174_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 494.0
HFD2_k127_4565174_9 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 486.0
HFD2_k127_4579056_0 indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 7.814e-307 980.0
HFD2_k127_4579056_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 3.215e-223 720.0
HFD2_k127_4579056_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
HFD2_k127_4579056_11 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000006873 209.0
HFD2_k127_4579056_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000719 205.0
HFD2_k127_4579056_13 Dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000006055 194.0
HFD2_k127_4579056_14 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000003136 189.0
HFD2_k127_4579056_15 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000001815 195.0
HFD2_k127_4579056_16 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000003091 174.0
HFD2_k127_4579056_17 3-oxoadipate enol-lactonase K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000007473 138.0
HFD2_k127_4579056_18 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0001701 52.0
HFD2_k127_4579056_2 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 2.392e-215 678.0
HFD2_k127_4579056_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 2.529e-207 650.0
HFD2_k127_4579056_4 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 533.0
HFD2_k127_4579056_5 Protein synonym acyl-CoA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 514.0
HFD2_k127_4579056_6 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 500.0
HFD2_k127_4579056_7 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 377.0
HFD2_k127_4579056_8 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001392 268.0
HFD2_k127_4579056_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000248 225.0
HFD2_k127_4583550_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 602.0
HFD2_k127_4583550_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 462.0
HFD2_k127_4583550_10 GGDEF domain - - - 0.00000000000000000000000000000000005986 148.0
HFD2_k127_4583550_11 Serine threonine protein kinase - - - 0.00000000000000000000000002031 129.0
HFD2_k127_4583550_12 Hemerythrin HHE cation binding domain - - - 0.00000000000000009703 86.0
HFD2_k127_4583550_2 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 449.0
HFD2_k127_4583550_3 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 440.0
HFD2_k127_4583550_4 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 392.0
HFD2_k127_4583550_5 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 321.0
HFD2_k127_4583550_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
HFD2_k127_4583550_7 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
HFD2_k127_4583550_8 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000009348 273.0
HFD2_k127_4583550_9 transcriptional regulator, SARP family - - - 0.00000000000000000000000000000000005185 157.0
HFD2_k127_4595040_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 553.0
HFD2_k127_4595040_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 412.0
HFD2_k127_4595040_11 - - - - 0.0008417 51.0
HFD2_k127_4595040_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 378.0
HFD2_k127_4595040_3 PFAM Peptidase family S58 K18572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 323.0
HFD2_k127_4595040_4 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 300.0
HFD2_k127_4595040_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
HFD2_k127_4595040_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 296.0
HFD2_k127_4595040_7 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000001696 241.0
HFD2_k127_4595040_8 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000003473 207.0
HFD2_k127_4595040_9 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000000000000000007155 181.0
HFD2_k127_4646406_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1063.0
HFD2_k127_4646406_1 Acetylornithine deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 513.0
HFD2_k127_4646406_10 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000001462 203.0
HFD2_k127_4646406_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000007102 190.0
HFD2_k127_4646406_12 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000006071 151.0
HFD2_k127_4646406_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000003847 139.0
HFD2_k127_4646406_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000005301 137.0
HFD2_k127_4646406_15 - - - - 0.0000000000000000000000000000000001854 145.0
HFD2_k127_4646406_16 acyl-CoA dehydrogenase - - - 0.0000000000000000000000002626 122.0
HFD2_k127_4646406_17 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000002633 97.0
HFD2_k127_4646406_19 MRF binding K04498 GO:0000003,GO:0000075,GO:0000076,GO:0000122,GO:0000123,GO:0000228,GO:0000775,GO:0000776,GO:0000777,GO:0000779,GO:0000785,GO:0000790,GO:0000793,GO:0000940,GO:0000976,GO:0000977,GO:0000981,GO:0000982,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001078,GO:0001085,GO:0001091,GO:0001093,GO:0001098,GO:0001099,GO:0001102,GO:0001191,GO:0001227,GO:0001228,GO:0001505,GO:0001654,GO:0001666,GO:0001736,GO:0001738,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001817,GO:0001818,GO:0001819,GO:0002009,GO:0002039,GO:0002064,GO:0002065,GO:0002066,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002520,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003690,GO:0003700,GO:0003712,GO:0003713,GO:0003824,GO:0004402,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005737,GO:0006139,GO:0006325,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006464,GO:0006473,GO:0006474,GO:0006475,GO:0006479,GO:0006725,GO:0006807,GO:0006810,GO:0006836,GO:0006928,GO:0006950,GO:0006996,GO:0007088,GO:0007154,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007224,GO:0007267,GO:0007268,GO:0007269,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007346,GO:0007399,GO:0007416,GO:0007423,GO:0007464,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008140,GO:0008150,GO:0008152,GO:0008213,GO:0008270,GO:0008283,GO:0008347,GO:0008589,GO:0008593,GO:0009058,GO:0009059,GO:0009266,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010484,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016043,GO:0016055,GO:0016070,GO:0016407,GO:0016410,GO:0016477,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016604,GO:0016605,GO:0016740,GO:0016746,GO:0016747,GO:0018022,GO:0018076,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019216,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019827,GO:0019899,GO:0019904,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0023061,GO:0030097,GO:0030111,GO:0030154,GO:0030177,GO:0030178,GO:0030182,GO:0030326,GO:0030707,GO:0030718,GO:0030855,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031349,GO:0031365,GO:0031570,GO:0031647,GO:0031648,GO:0031974,GO:0031981,GO:0032259,GO:0032479,GO:0032480,GO:0032481,GO:0032501,GO:0032502,GO:0032504,GO:0032648,GO:0032688,GO:0032774,GO:0032793,GO:0032922,GO:0032940,GO:0032991,GO:0033043,GO:0033554,GO:0033613,GO:0034097,GO:0034212,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034708,GO:0034968,GO:0035097,GO:0035107,GO:0035108,GO:0035113,GO:0035728,GO:0035729,GO:0036211,GO:0036293,GO:0036294,GO:0040011,GO:0040040,GO:0042035,GO:0042036,GO:0042063,GO:0042067,GO:0042221,GO:0042592,GO:0042706,GO:0042733,GO:0042975,GO:0042981,GO:0043067,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043425,GO:0043426,GO:0043543,GO:0043565,GO:0043618,GO:0043620,GO:0043900,GO:0043901,GO:0043903,GO:0043933,GO:0043966,GO:0043967,GO:0043971,GO:0043974,GO:0043982,GO:0043983,GO:0043993,GO:0044017,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0044798,GO:0045088,GO:0045089,GO:0045165,GO:0045357,GO:0045358,GO:0045466,GO:0045475,GO:0045595,GO:0045637,GO:0045747,GO:0045786,GO:0045787,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045944,GO:0046332,GO:0046483,GO:0046530,GO:0046552,GO:0046872,GO:0046903,GO:0046914,GO:0046982,GO:0046983,GO:0048056,GO:0048468,GO:0048477,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048598,GO:0048609,GO:0048663,GO:0048699,GO:0048729,GO:0048731,GO:0048736,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050808,GO:0050896,GO:0051090,GO:0051091,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051604,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051783,GO:0060173,GO:0060255,GO:0060353,GO:0060355,GO:0060429,GO:0060828,GO:0061418,GO:0061733,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070482,GO:0070555,GO:0070848,GO:0070887,GO:0071214,GO:0071310,GO:0071363,GO:0071453,GO:0071456,GO:0071478,GO:0071482,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090090,GO:0090263,GO:0090304,GO:0090575,GO:0090596,GO:0097159,GO:0097659,GO:0097718,GO:0098586,GO:0098687,GO:0098727,GO:0098916,GO:0099536,GO:0099537,GO:0099643,GO:0104004,GO:0140110,GO:0198738,GO:1900034,GO:1900087,GO:1901222,GO:1901224,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902493,GO:1902494,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1902806,GO:1902808,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1904837,GO:1905114,GO:1990226,GO:1990234,GO:1990837,GO:2000026,GO:2000045,GO:2000112,GO:2000113,GO:2001141 2.3.1.48 0.0008316 44.0
HFD2_k127_4646406_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 477.0
HFD2_k127_4646406_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 447.0
HFD2_k127_4646406_4 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 434.0
HFD2_k127_4646406_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 329.0
HFD2_k127_4646406_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002527 280.0
HFD2_k127_4646406_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
HFD2_k127_4646406_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000002235 258.0
HFD2_k127_4646406_9 Lysyl oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001386 229.0
HFD2_k127_4694175_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K02567 - 1.17.1.9 0.0 1199.0
HFD2_k127_4694175_1 haloacid dehalogenase-like hydrolase - - - 0.0 1122.0
HFD2_k127_4694175_10 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 314.0
HFD2_k127_4694175_11 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001542 300.0
HFD2_k127_4694175_12 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003265 270.0
HFD2_k127_4694175_13 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004991 259.0
HFD2_k127_4694175_14 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000005451 245.0
HFD2_k127_4694175_15 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000001173 203.0
HFD2_k127_4694175_16 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000001305 189.0
HFD2_k127_4694175_17 AsnC family K03718 - - 0.000000000000000000000000000000000000000000000000000215 193.0
HFD2_k127_4694175_18 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000002214 208.0
HFD2_k127_4694175_19 - - - - 0.000000000000000000000000000000000000000000000000001409 187.0
HFD2_k127_4694175_2 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.206e-234 733.0
HFD2_k127_4694175_20 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000002479 187.0
HFD2_k127_4694175_21 competence protein COMEC - - - 0.0000000000000000000000000000000000000005145 173.0
HFD2_k127_4694175_22 - - - - 0.0000000000000000000000000000000000005209 146.0
HFD2_k127_4694175_23 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000000277 149.0
HFD2_k127_4694175_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001283 138.0
HFD2_k127_4694175_25 translation initiation factor activity - - - 0.0000000000000000000000000001363 132.0
HFD2_k127_4694175_26 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000001983 121.0
HFD2_k127_4694175_27 - - - - 0.00000000000000000000000005552 111.0
HFD2_k127_4694175_28 DnaJ-class molecular chaperone with C-terminal Zn finger domain K03686 - - 0.000000000000001459 86.0
HFD2_k127_4694175_29 - - - - 0.0000000004914 62.0
HFD2_k127_4694175_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 566.0
HFD2_k127_4694175_4 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 520.0
HFD2_k127_4694175_5 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 437.0
HFD2_k127_4694175_6 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 449.0
HFD2_k127_4694175_7 TOBE domain K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 430.0
HFD2_k127_4694175_8 Bacterial extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
HFD2_k127_4694175_9 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 407.0
HFD2_k127_4701268_0 Oligopeptidase F K08602 - - 1.232e-247 789.0
HFD2_k127_4701268_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 501.0
HFD2_k127_4701268_10 - - - - 0.00000000000000000000002831 106.0
HFD2_k127_4701268_11 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.0000000007383 72.0
HFD2_k127_4701268_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 488.0
HFD2_k127_4701268_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 320.0
HFD2_k127_4701268_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 297.0
HFD2_k127_4701268_5 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001857 286.0
HFD2_k127_4701268_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000171 262.0
HFD2_k127_4701268_7 heme binding K06401,K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000002718 238.0
HFD2_k127_4701268_8 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000002567 176.0
HFD2_k127_4703047_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1339.0
HFD2_k127_4703047_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.129e-307 962.0
HFD2_k127_4703047_10 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 462.0
HFD2_k127_4703047_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 447.0
HFD2_k127_4703047_12 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 454.0
HFD2_k127_4703047_13 Polyprenyl synthetase K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 425.0
HFD2_k127_4703047_14 DisA bacterial checkpoint controller linker region K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 413.0
HFD2_k127_4703047_15 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 377.0
HFD2_k127_4703047_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 366.0
HFD2_k127_4703047_17 carbohydrate transport K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 379.0
HFD2_k127_4703047_19 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 342.0
HFD2_k127_4703047_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.599e-246 773.0
HFD2_k127_4703047_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 344.0
HFD2_k127_4703047_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 332.0
HFD2_k127_4703047_22 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 327.0
HFD2_k127_4703047_23 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 332.0
HFD2_k127_4703047_24 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 306.0
HFD2_k127_4703047_25 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 302.0
HFD2_k127_4703047_26 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 288.0
HFD2_k127_4703047_27 Binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 290.0
HFD2_k127_4703047_28 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000612 276.0
HFD2_k127_4703047_29 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008843 280.0
HFD2_k127_4703047_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.958e-237 747.0
HFD2_k127_4703047_30 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
HFD2_k127_4703047_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HFD2_k127_4703047_32 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009244 254.0
HFD2_k127_4703047_33 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001854 243.0
HFD2_k127_4703047_34 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HFD2_k127_4703047_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001449 215.0
HFD2_k127_4703047_36 - - - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
HFD2_k127_4703047_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000006937 179.0
HFD2_k127_4703047_38 - - - - 0.0000000000000000000000000000000000000000000162 171.0
HFD2_k127_4703047_4 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 582.0
HFD2_k127_4703047_40 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000007517 157.0
HFD2_k127_4703047_41 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.0000000000000000000000000000000000001576 144.0
HFD2_k127_4703047_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000372 136.0
HFD2_k127_4703047_43 amine dehydrogenase activity K07004,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000001118 119.0
HFD2_k127_4703047_44 amine dehydrogenase activity - - - 0.0000000000000000000000002937 119.0
HFD2_k127_4703047_5 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 553.0
HFD2_k127_4703047_6 KaiC K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 524.0
HFD2_k127_4703047_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 516.0
HFD2_k127_4703047_8 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 479.0
HFD2_k127_4703047_9 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
HFD2_k127_4714947_0 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 518.0
HFD2_k127_4714947_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 488.0
HFD2_k127_4714947_10 CBS domain containing protein K03699 - - 0.0000000000000051 78.0
HFD2_k127_4714947_2 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
HFD2_k127_4714947_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 353.0
HFD2_k127_4714947_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 346.0
HFD2_k127_4714947_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 320.0
HFD2_k127_4714947_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005625 284.0
HFD2_k127_4714947_7 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002928 244.0
HFD2_k127_4714947_8 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
HFD2_k127_4714947_9 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000002048 86.0
HFD2_k127_4775425_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 509.0
HFD2_k127_4775425_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 365.0
HFD2_k127_4775425_10 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000001731 122.0
HFD2_k127_4775425_11 Rieske 2Fe-2S K00479 - - 0.000000000000000000000003866 102.0
HFD2_k127_4775425_12 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000003443 95.0
HFD2_k127_4775425_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HFD2_k127_4775425_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HFD2_k127_4775425_4 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000001418 212.0
HFD2_k127_4775425_5 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000000000001167 196.0
HFD2_k127_4775425_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001732 197.0
HFD2_k127_4775425_7 dehydratase - - - 0.000000000000000000000000000000000000000000000000003489 188.0
HFD2_k127_4775425_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001084 188.0
HFD2_k127_4775425_9 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000000000001732 180.0
HFD2_k127_485077_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1291.0
HFD2_k127_485077_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 455.0
HFD2_k127_485077_11 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000003887 169.0
HFD2_k127_485077_12 thiolester hydrolase activity K17362 - - 0.00000000000000000000000001611 126.0
HFD2_k127_485077_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000004343 108.0
HFD2_k127_485077_14 Alpha/beta hydrolase family K06889 - - 0.00000000001657 76.0
HFD2_k127_485077_2 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 388.0
HFD2_k127_485077_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 328.0
HFD2_k127_485077_4 Transposase, mutator K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001274 260.0
HFD2_k127_485077_5 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
HFD2_k127_485077_6 peptidase activity K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000005559 241.0
HFD2_k127_485077_7 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
HFD2_k127_485077_8 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000232 186.0
HFD2_k127_485077_9 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001059 179.0
HFD2_k127_4869588_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.337e-277 870.0
HFD2_k127_4869588_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.026e-253 799.0
HFD2_k127_4869588_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000139 243.0
HFD2_k127_4869588_11 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000005182 208.0
HFD2_k127_4869588_12 - - - - 0.000000000000000000000000000000000000000000000001185 186.0
HFD2_k127_4869588_13 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000007613 186.0
HFD2_k127_4869588_14 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000000006685 182.0
HFD2_k127_4869588_15 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000007694 157.0
HFD2_k127_4869588_16 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.000000000000000000000000000000002463 137.0
HFD2_k127_4869588_18 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000000005473 96.0
HFD2_k127_4869588_19 nuclease K01174 - 3.1.31.1 0.000000000000000005285 92.0
HFD2_k127_4869588_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.381e-242 758.0
HFD2_k127_4869588_3 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 465.0
HFD2_k127_4869588_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 460.0
HFD2_k127_4869588_5 tRNA methyl transferase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 469.0
HFD2_k127_4869588_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HFD2_k127_4869588_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 425.0
HFD2_k127_4869588_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 346.0
HFD2_k127_4869588_9 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 321.0
HFD2_k127_4882462_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.774e-232 747.0
HFD2_k127_4882462_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 3.047e-224 703.0
HFD2_k127_4882462_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
HFD2_k127_4882462_11 chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 293.0
HFD2_k127_4882462_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 304.0
HFD2_k127_4882462_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
HFD2_k127_4882462_14 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001079 286.0
HFD2_k127_4882462_15 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
HFD2_k127_4882462_16 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
HFD2_k127_4882462_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000007897 253.0
HFD2_k127_4882462_18 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001504 254.0
HFD2_k127_4882462_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001399 210.0
HFD2_k127_4882462_2 GTP-binding protein TypA K06207 - - 5.576e-210 673.0
HFD2_k127_4882462_20 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.000000000000000000000000000000000000000000000000004581 186.0
HFD2_k127_4882462_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000001737 187.0
HFD2_k127_4882462_22 Protein of unknown function (DUF3151) - - - 0.00000000000000000000000000000000000000000000000521 175.0
HFD2_k127_4882462_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000652 158.0
HFD2_k127_4882462_24 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.0000000000000000000000000000000000000001122 169.0
HFD2_k127_4882462_25 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000005946 152.0
HFD2_k127_4882462_26 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000144 144.0
HFD2_k127_4882462_27 Methyltransferase domain - - - 0.000000000000000000000000000000000003744 155.0
HFD2_k127_4882462_28 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000003728 130.0
HFD2_k127_4882462_29 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.7.77 0.00000000000000000000003043 106.0
HFD2_k127_4882462_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 611.0
HFD2_k127_4882462_30 Rhodanese Homology Domain - - - 0.000000000000000000001424 102.0
HFD2_k127_4882462_32 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000006769 98.0
HFD2_k127_4882462_33 xylulose kinase K00854 - 2.7.1.17 0.0000000000001918 73.0
HFD2_k127_4882462_4 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 531.0
HFD2_k127_4882462_5 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 479.0
HFD2_k127_4882462_6 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 482.0
HFD2_k127_4882462_7 3-dehydroquinate synthase K16020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 440.0
HFD2_k127_4882462_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 406.0
HFD2_k127_4882462_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
HFD2_k127_4933609_0 Acetyl-CoA carboxylase, central region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 439.0
HFD2_k127_4933609_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004396 258.0
HFD2_k127_4933609_2 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000004254 244.0
HFD2_k127_4933609_3 PFAM Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
HFD2_k127_4933609_4 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000008356 127.0
HFD2_k127_4962795_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 478.0
HFD2_k127_4962795_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002288 277.0
HFD2_k127_4962795_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000002921 242.0
HFD2_k127_4962795_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002386 229.0
HFD2_k127_4962795_4 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000004461 139.0
HFD2_k127_4962795_5 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.00000000000000000000004105 103.0
HFD2_k127_4962795_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000001524 85.0
HFD2_k127_4962795_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000001307 76.0
HFD2_k127_4992210_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.241e-232 726.0
HFD2_k127_4992210_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 530.0
HFD2_k127_4992210_10 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 296.0
HFD2_k127_4992210_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007781 244.0
HFD2_k127_4992210_12 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001126 226.0
HFD2_k127_4992210_13 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
HFD2_k127_4992210_14 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000007179 162.0
HFD2_k127_4992210_15 resistance protein CopC K14166 - - 0.000000000000000000000000000000000000001904 169.0
HFD2_k127_4992210_16 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.00000000000000000000000000000000000003575 151.0
HFD2_k127_4992210_17 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000000000000005372 144.0
HFD2_k127_4992210_18 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000019 120.0
HFD2_k127_4992210_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000001069 110.0
HFD2_k127_4992210_2 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 490.0
HFD2_k127_4992210_20 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000001829 77.0
HFD2_k127_4992210_21 universal stress protein - - - 0.00000000006684 71.0
HFD2_k127_4992210_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 452.0
HFD2_k127_4992210_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 419.0
HFD2_k127_4992210_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
HFD2_k127_4992210_6 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 340.0
HFD2_k127_4992210_7 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 349.0
HFD2_k127_4992210_8 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 316.0
HFD2_k127_4992210_9 NifU-like domain K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
HFD2_k127_5025893_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1072.0
HFD2_k127_5025893_1 ATPases associated with a variety of cellular activities K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 565.0
HFD2_k127_5025893_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 403.0
HFD2_k127_5025893_3 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 379.0
HFD2_k127_5025893_4 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000002723 232.0
HFD2_k127_5025893_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000001667 199.0
HFD2_k127_5025893_6 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000005552 145.0
HFD2_k127_5025893_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000007761 78.0
HFD2_k127_5275608_0 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 533.0
HFD2_k127_5275608_1 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 532.0
HFD2_k127_5275608_10 Protein of unknown function (DUF3618) - - - 0.0000000000000000000000002343 117.0
HFD2_k127_5275608_12 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000001389 99.0
HFD2_k127_5275608_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000009434 88.0
HFD2_k127_5275608_16 TadE-like protein - - - 0.0000009125 58.0
HFD2_k127_5275608_2 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 471.0
HFD2_k127_5275608_3 Type ii secretion system - - - 0.00000000000000000000000000000000000000000000000000000000001637 219.0
HFD2_k127_5275608_4 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000001099 210.0
HFD2_k127_5275608_5 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000001267 180.0
HFD2_k127_5275608_6 SAF - - - 0.000000000000000000000000000000000000002781 155.0
HFD2_k127_5275608_7 LysM domain K12204 - - 0.000000000000000000000000000000000000006908 160.0
HFD2_k127_5289263_0 ThiF family - - - 3.039e-203 637.0
HFD2_k127_5289263_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 415.0
HFD2_k127_5289263_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 407.0
HFD2_k127_5289263_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 391.0
HFD2_k127_5289263_4 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 349.0
HFD2_k127_5289263_6 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000009379 145.0
HFD2_k127_5289263_7 Nitroreductase family - - - 0.0000000000000000002294 102.0
HFD2_k127_5296691_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.024e-293 915.0
HFD2_k127_5296691_1 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 609.0
HFD2_k127_5296691_10 Major facilitator Superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001204 227.0
HFD2_k127_5296691_11 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000000003242 143.0
HFD2_k127_5296691_12 - - - - 0.00000000000000000000004279 103.0
HFD2_k127_5296691_13 Glucose / Sorbosone dehydrogenase - - - 0.00000000002165 66.0
HFD2_k127_5296691_14 protein secretion K03116 - - 0.000000002875 59.0
HFD2_k127_5296691_2 RNB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 515.0
HFD2_k127_5296691_3 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 453.0
HFD2_k127_5296691_4 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 364.0
HFD2_k127_5296691_5 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HFD2_k127_5296691_6 Epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 327.0
HFD2_k127_5296691_7 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 306.0
HFD2_k127_5296691_8 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 304.0
HFD2_k127_5296691_9 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001108 239.0
HFD2_k127_5306571_0 elongation factor Tu domain 2 protein K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 2.924e-288 902.0
HFD2_k127_5306571_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 4.054e-218 693.0
HFD2_k127_5306571_10 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 323.0
HFD2_k127_5306571_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001817 287.0
HFD2_k127_5306571_12 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
HFD2_k127_5306571_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005999 250.0
HFD2_k127_5306571_14 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000000001743 209.0
HFD2_k127_5306571_15 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000006331 202.0
HFD2_k127_5306571_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000004188 176.0
HFD2_k127_5306571_17 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000004668 186.0
HFD2_k127_5306571_19 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.000000000000000000000000000000000000000008723 159.0
HFD2_k127_5306571_2 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 476.0
HFD2_k127_5306571_20 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000001889 165.0
HFD2_k127_5306571_21 Cbs domain - - - 0.0000000000000000000000000000000000000001795 154.0
HFD2_k127_5306571_22 Trehalose synthase - - - 0.000000000000000000000000000000000000001923 157.0
HFD2_k127_5306571_23 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs - - - 0.0000000000000000000000000000000003676 152.0
HFD2_k127_5306571_24 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000002798 133.0
HFD2_k127_5306571_25 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000002663 120.0
HFD2_k127_5306571_26 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000002553 99.0
HFD2_k127_5306571_28 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000008607 94.0
HFD2_k127_5306571_29 - - - - 0.00000000001156 69.0
HFD2_k127_5306571_3 AAA domain K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
HFD2_k127_5306571_30 antisigma factor binding K04749 - - 0.0000000001135 68.0
HFD2_k127_5306571_31 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000002019 62.0
HFD2_k127_5306571_32 antisigma factor binding - - - 0.0000002249 59.0
HFD2_k127_5306571_33 Histidine kinase-like ATPase domain - - - 0.000001043 57.0
HFD2_k127_5306571_4 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 443.0
HFD2_k127_5306571_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
HFD2_k127_5306571_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 365.0
HFD2_k127_5306571_7 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 379.0
HFD2_k127_5306571_8 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 367.0
HFD2_k127_5306571_9 Short-chain dehydrogenase reductase sdr K14633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 331.0
HFD2_k127_5310829_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 559.0
HFD2_k127_5310829_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 516.0
HFD2_k127_5310829_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000413 139.0
HFD2_k127_5310829_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000005773 124.0
HFD2_k127_5310829_12 lycopene cyclase - - - 0.0000000000000000000000000000917 118.0
HFD2_k127_5310829_13 carotenoid biosynthetic process - - - 0.00000000000000000000000001374 121.0
HFD2_k127_5310829_14 hydroxylase K15746 - 1.14.15.24 0.000000000000000000000003817 115.0
HFD2_k127_5310829_15 Belongs to the ompA family K20276 - - 0.00000000000005381 83.0
HFD2_k127_5310829_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 320.0
HFD2_k127_5310829_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005447 275.0
HFD2_k127_5310829_4 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000008551 269.0
HFD2_k127_5310829_5 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
HFD2_k127_5310829_6 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000001776 211.0
HFD2_k127_5310829_7 Cobalamin B12-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000533 209.0
HFD2_k127_5310829_8 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000001595 214.0
HFD2_k127_5310829_9 lycopene cyclase - - - 0.00000000000000000000000000000000001466 141.0
HFD2_k127_5342000_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1607.0
HFD2_k127_5342000_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
HFD2_k127_5342000_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000008494 220.0
HFD2_k127_5342000_3 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000001817 149.0
HFD2_k127_5365885_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1380.0
HFD2_k127_5365885_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.301e-309 981.0
HFD2_k127_5365885_10 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 410.0
HFD2_k127_5365885_11 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 369.0
HFD2_k127_5365885_12 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 367.0
HFD2_k127_5365885_13 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 355.0
HFD2_k127_5365885_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 355.0
HFD2_k127_5365885_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
HFD2_k127_5365885_16 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 355.0
HFD2_k127_5365885_17 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 355.0
HFD2_k127_5365885_18 amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 297.0
HFD2_k127_5365885_19 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 291.0
HFD2_k127_5365885_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.935e-229 726.0
HFD2_k127_5365885_20 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 289.0
HFD2_k127_5365885_21 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001618 285.0
HFD2_k127_5365885_22 GCN5 family acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003022 285.0
HFD2_k127_5365885_23 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
HFD2_k127_5365885_24 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
HFD2_k127_5365885_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
HFD2_k127_5365885_26 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000008321 238.0
HFD2_k127_5365885_27 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000001439 243.0
HFD2_k127_5365885_28 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000006558 229.0
HFD2_k127_5365885_29 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001242 241.0
HFD2_k127_5365885_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.315e-205 652.0
HFD2_k127_5365885_30 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.0000000000000000000000000000000000000000000000000000000008738 231.0
HFD2_k127_5365885_31 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000002498 184.0
HFD2_k127_5365885_32 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000005331 193.0
HFD2_k127_5365885_33 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000004106 182.0
HFD2_k127_5365885_34 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000001094 156.0
HFD2_k127_5365885_35 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000004438 142.0
HFD2_k127_5365885_36 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000005294 139.0
HFD2_k127_5365885_37 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000006271 128.0
HFD2_k127_5365885_38 Dimerisation domain - - - 0.00000000000000000001881 106.0
HFD2_k127_5365885_39 Protein of unknown function (DUF861) - - - 0.0000000000000000002798 97.0
HFD2_k127_5365885_4 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 581.0
HFD2_k127_5365885_40 Protein of unknown function (DUF664) - - - 0.000000000000000007272 87.0
HFD2_k127_5365885_41 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000003432 87.0
HFD2_k127_5365885_43 helix_turn_helix, mercury resistance K22491 - - 0.0000000009378 70.0
HFD2_k127_5365885_44 Phosphopantetheine attachment site - - - 0.000000001376 63.0
HFD2_k127_5365885_45 Transposase IS116/IS110/IS902 family - - - 0.000007753 57.0
HFD2_k127_5365885_46 antisigma factor binding K06378 - - 0.000007932 53.0
HFD2_k127_5365885_47 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0008612 50.0
HFD2_k127_5365885_5 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 486.0
HFD2_k127_5365885_6 Circadian clock protein KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 486.0
HFD2_k127_5365885_7 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 459.0
HFD2_k127_5365885_8 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 446.0
HFD2_k127_5365885_9 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
HFD2_k127_5377518_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 560.0
HFD2_k127_5377518_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 507.0
HFD2_k127_5377518_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000002642 182.0
HFD2_k127_5377518_11 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000002064 175.0
HFD2_k127_5377518_12 Subtilase family - - - 0.000000000000000000000000000000000001224 156.0
HFD2_k127_5377518_13 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000001702 136.0
HFD2_k127_5377518_14 - - - - 0.0000000000000000000000000445 117.0
HFD2_k127_5377518_15 flavoprotein K19784 - - 0.00000000000000000000000006133 113.0
HFD2_k127_5377518_16 - - - - 0.000000000000000000000003204 112.0
HFD2_k127_5377518_17 - - - - 0.00000000000000000002274 101.0
HFD2_k127_5377518_18 - - - - 0.00000000000000157 89.0
HFD2_k127_5377518_19 Transport permease protein K01992 - - 0.000000000000005552 86.0
HFD2_k127_5377518_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007925 259.0
HFD2_k127_5377518_20 Transcriptional regulator - - - 0.000004589 57.0
HFD2_k127_5377518_3 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001481 273.0
HFD2_k127_5377518_4 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000003426 234.0
HFD2_k127_5377518_5 ABC transporter K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000006464 230.0
HFD2_k127_5377518_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000004316 216.0
HFD2_k127_5377518_7 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000000000008557 219.0
HFD2_k127_5377518_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000005179 203.0
HFD2_k127_5377518_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000244 173.0
HFD2_k127_5388724_0 ABC transporter transmembrane region K06147 - - 3.419e-266 834.0
HFD2_k127_5388724_1 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 4.432e-250 784.0
HFD2_k127_5388724_10 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
HFD2_k127_5388724_11 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000002606 235.0
HFD2_k127_5388724_12 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000006502 232.0
HFD2_k127_5388724_13 Phage-related minor tail protein K15771,K18642,K20444 - - 0.000000000000000000000000000000000000000000000000000000003394 217.0
HFD2_k127_5388724_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000001965 190.0
HFD2_k127_5388724_15 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001339 184.0
HFD2_k127_5388724_16 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000001231 186.0
HFD2_k127_5388724_17 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000005017 169.0
HFD2_k127_5388724_18 - - - - 0.0000000000000000000000000000000000000003809 165.0
HFD2_k127_5388724_2 Zinc-binding dehydrogenase K17829 - 1.3.1.86 3.1e-210 660.0
HFD2_k127_5388724_20 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000003697 113.0
HFD2_k127_5388724_21 pyridoxamine 5-phosphate K07005 - - 0.00000000000000000000005518 103.0
HFD2_k127_5388724_22 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000003653 74.0
HFD2_k127_5388724_23 Prokaryotic N-terminal methylation motif - - - 0.0000000000006346 75.0
HFD2_k127_5388724_24 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000001104 74.0
HFD2_k127_5388724_25 protein secretion K03116 - - 0.00000001733 60.0
HFD2_k127_5388724_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 592.0
HFD2_k127_5388724_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 549.0
HFD2_k127_5388724_5 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 559.0
HFD2_k127_5388724_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 444.0
HFD2_k127_5388724_7 5'-3' exonuclease, C-terminal SAM fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 387.0
HFD2_k127_5388724_8 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 353.0
HFD2_k127_5388724_9 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
HFD2_k127_5390952_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 463.0
HFD2_k127_5390952_1 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000002441 195.0
HFD2_k127_5390952_2 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000001387 160.0
HFD2_k127_5390952_3 Cyclic nucleotide-binding domain - - - 0.000000000000000243 89.0
HFD2_k127_5390952_4 Peptidoglycan-binding domain 1 protein - - - 0.0001331 52.0
HFD2_k127_5399163_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 1.163e-284 884.0
HFD2_k127_5399163_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
HFD2_k127_5399163_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
HFD2_k127_5399163_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000001181 197.0
HFD2_k127_5399163_4 Putative zinc-finger - - - 0.00000000001505 67.0
HFD2_k127_5399163_5 Glycogen debranching enzyme N terminal - - - 0.00000000007233 63.0
HFD2_k127_5401394_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 8.042e-216 689.0
HFD2_k127_5401394_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 331.0
HFD2_k127_5401394_10 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
HFD2_k127_5401394_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
HFD2_k127_5401394_12 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000004275 199.0
HFD2_k127_5401394_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000003792 216.0
HFD2_k127_5401394_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000001799 187.0
HFD2_k127_5401394_15 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000002181 183.0
HFD2_k127_5401394_16 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000001151 151.0
HFD2_k127_5401394_17 Inositol monophosphatase family K05602 - 3.1.3.15 0.000000000000000000000000000000000000214 164.0
HFD2_k127_5401394_18 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000222 101.0
HFD2_k127_5401394_19 ERCC4 domain - - - 0.00004446 49.0
HFD2_k127_5401394_2 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 340.0
HFD2_k127_5401394_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 311.0
HFD2_k127_5401394_4 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 314.0
HFD2_k127_5401394_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
HFD2_k127_5401394_6 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006872 293.0
HFD2_k127_5401394_7 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004254 273.0
HFD2_k127_5401394_8 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003712 287.0
HFD2_k127_5401394_9 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000002747 256.0
HFD2_k127_5405007_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 480.0
HFD2_k127_5405007_1 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 456.0
HFD2_k127_5405007_2 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 324.0
HFD2_k127_5405007_3 ATP-NAD kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005015 287.0
HFD2_k127_5405007_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000008952 98.0
HFD2_k127_5405007_5 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000041 67.0
HFD2_k127_5432748_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1451.0
HFD2_k127_5432748_1 regulation of cell shape - - - 0.0000000000000000000000000000000000000000000000000000009782 203.0
HFD2_k127_5432748_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000000000000000000000000000000000003585 186.0
HFD2_k127_5432748_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000001084 165.0
HFD2_k127_5432748_4 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000000000000000000000002361 132.0
HFD2_k127_5458907_0 Belongs to the thiolase family - - - 3.686e-209 655.0
HFD2_k127_5458907_1 PFAM regulatory protein ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 398.0
HFD2_k127_5458907_10 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000006055 196.0
HFD2_k127_5458907_11 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000002329 191.0
HFD2_k127_5458907_12 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000007649 190.0
HFD2_k127_5458907_13 synthetase - - - 0.000000000000000000000000000000000000000004943 156.0
HFD2_k127_5458907_14 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.0000000000000000000000000000002689 128.0
HFD2_k127_5458907_15 Transglycosylase associated protein - - - 0.0000000000000000000000000000008587 123.0
HFD2_k127_5458907_16 dipeptide transport K02035 - - 0.000000000000059 84.0
HFD2_k127_5458907_19 Glycosyl hydrolases family 25 K07273 - - 0.0003003 53.0
HFD2_k127_5458907_2 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 357.0
HFD2_k127_5458907_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 341.0
HFD2_k127_5458907_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
HFD2_k127_5458907_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001487 285.0
HFD2_k127_5458907_6 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002606 285.0
HFD2_k127_5458907_7 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 242.0
HFD2_k127_5458907_8 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000217 239.0
HFD2_k127_5458907_9 cytochrome complex assembly K02200,K04018 - - 0.00000000000000000000000000000000000000000000000000000000000000005035 244.0
HFD2_k127_5473914_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 507.0
HFD2_k127_5473914_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 501.0
HFD2_k127_5473914_2 deiminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 462.0
HFD2_k127_5473914_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005705 285.0
HFD2_k127_5473914_4 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000008433 219.0
HFD2_k127_5473914_5 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000004256 196.0
HFD2_k127_5473914_6 amine dehydrogenase activity K01077,K07004,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.3.1 0.00000000000000000000000000000000001005 145.0
HFD2_k127_5490739_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.125e-302 949.0
HFD2_k127_5490739_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.193e-244 765.0
HFD2_k127_5490739_2 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 1.505e-206 654.0
HFD2_k127_5490739_3 Glycosylase K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000009378 215.0
HFD2_k127_5490739_4 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000214 145.0
HFD2_k127_5490739_5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.00000001776 65.0
HFD2_k127_5524226_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.839e-276 857.0
HFD2_k127_5524226_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 520.0
HFD2_k127_5524226_10 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000006723 246.0
HFD2_k127_5524226_11 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000005107 225.0
HFD2_k127_5524226_12 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000001309 192.0
HFD2_k127_5524226_13 ThiS family K03636 - - 0.00000000000000000000000000001804 120.0
HFD2_k127_5524226_16 Fungalysin metallopeptidase (M36) - - - 0.0000000000006136 82.0
HFD2_k127_5524226_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 372.0
HFD2_k127_5524226_3 Glycerate kinase family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 374.0
HFD2_k127_5524226_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 374.0
HFD2_k127_5524226_5 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 347.0
HFD2_k127_5524226_6 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 319.0
HFD2_k127_5524226_7 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
HFD2_k127_5524226_8 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000008353 231.0
HFD2_k127_5524226_9 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000002541 225.0
HFD2_k127_5575905_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.176e-196 624.0
HFD2_k127_5575905_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 597.0
HFD2_k127_5575905_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 252.0
HFD2_k127_5575905_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004262 253.0
HFD2_k127_5575905_12 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 261.0
HFD2_k127_5575905_13 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000006625 256.0
HFD2_k127_5575905_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 240.0
HFD2_k127_5575905_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000007145 232.0
HFD2_k127_5575905_16 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
HFD2_k127_5575905_17 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD2_k127_5575905_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000006511 178.0
HFD2_k127_5575905_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000003658 161.0
HFD2_k127_5575905_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 472.0
HFD2_k127_5575905_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000004715 141.0
HFD2_k127_5575905_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000002935 140.0
HFD2_k127_5575905_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001031 120.0
HFD2_k127_5575905_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000002408 115.0
HFD2_k127_5575905_24 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002612 86.0
HFD2_k127_5575905_25 Ribosomal protein L30p/L7e K02907 - - 0.0000000000002262 81.0
HFD2_k127_5575905_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 459.0
HFD2_k127_5575905_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 409.0
HFD2_k127_5575905_5 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 389.0
HFD2_k127_5575905_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 311.0
HFD2_k127_5575905_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002617 286.0
HFD2_k127_5575905_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006793 274.0
HFD2_k127_5575905_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005995 263.0
HFD2_k127_5605338_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1364.0
HFD2_k127_5605338_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 602.0
HFD2_k127_5605338_10 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HFD2_k127_5605338_11 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 299.0
HFD2_k127_5605338_12 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005031 283.0
HFD2_k127_5605338_13 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HFD2_k127_5605338_14 Phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008957 255.0
HFD2_k127_5605338_15 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
HFD2_k127_5605338_16 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000000000000000000000000000000002365 178.0
HFD2_k127_5605338_17 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000006138 160.0
HFD2_k127_5605338_18 Universal stress protein family - - - 0.00000000000000000000000000000000000009978 153.0
HFD2_k127_5605338_19 Universal stress protein family - - - 0.000000000000000000000000000000000001142 152.0
HFD2_k127_5605338_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 522.0
HFD2_k127_5605338_20 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000001495 147.0
HFD2_k127_5605338_21 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000006919 128.0
HFD2_k127_5605338_22 Stress responsive A/B Barrel Domain - - - 0.000000000000008303 78.0
HFD2_k127_5605338_23 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000423 75.0
HFD2_k127_5605338_24 Ppx GppA phosphatase - - - 0.00008808 53.0
HFD2_k127_5605338_3 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 473.0
HFD2_k127_5605338_4 von Willebrand factor (vWF) type A domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 463.0
HFD2_k127_5605338_5 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 430.0
HFD2_k127_5605338_6 ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 430.0
HFD2_k127_5605338_7 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 439.0
HFD2_k127_5605338_8 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 397.0
HFD2_k127_5605338_9 von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
HFD2_k127_5630803_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 575.0
HFD2_k127_5630803_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
HFD2_k127_5630803_10 Nucleic acid binding, OB-fold, tRNA - - - 0.000000000003091 73.0
HFD2_k127_5630803_2 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 301.0
HFD2_k127_5630803_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007612 284.0
HFD2_k127_5630803_4 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006731 275.0
HFD2_k127_5630803_5 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
HFD2_k127_5630803_6 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000004188 222.0
HFD2_k127_5630803_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000003103 197.0
HFD2_k127_5630803_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000004415 122.0
HFD2_k127_5630803_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001204 106.0
HFD2_k127_5669868_0 PFAM carboxyl transferase - - - 4.543e-253 795.0
HFD2_k127_5669868_1 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 608.0
HFD2_k127_5669868_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
HFD2_k127_5669868_11 PFAM Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 334.0
HFD2_k127_5669868_12 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
HFD2_k127_5669868_13 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 305.0
HFD2_k127_5669868_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 298.0
HFD2_k127_5669868_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 300.0
HFD2_k127_5669868_16 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002109 278.0
HFD2_k127_5669868_17 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007186 260.0
HFD2_k127_5669868_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 254.0
HFD2_k127_5669868_19 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000001025 171.0
HFD2_k127_5669868_2 Flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 622.0
HFD2_k127_5669868_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000005318 154.0
HFD2_k127_5669868_21 response to heat K07090 - - 0.0000000000000000000000000000000003906 141.0
HFD2_k127_5669868_22 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000008615 130.0
HFD2_k127_5669868_23 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000002442 107.0
HFD2_k127_5669868_24 Transcriptional regulator - - - 0.0000000000000000000000003258 108.0
HFD2_k127_5669868_25 YhhN family - - - 0.000000000000000000000001935 111.0
HFD2_k127_5669868_26 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000293 103.0
HFD2_k127_5669868_27 CoA-binding domain protein - - - 0.000000000000000002817 94.0
HFD2_k127_5669868_29 glyoxalase III activity - - - 0.000000000000002996 82.0
HFD2_k127_5669868_3 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 523.0
HFD2_k127_5669868_30 - - - - 0.00000000009759 68.0
HFD2_k127_5669868_31 - - - - 0.0003273 52.0
HFD2_k127_5669868_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 465.0
HFD2_k127_5669868_5 DNA primase, small subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 448.0
HFD2_k127_5669868_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 417.0
HFD2_k127_5669868_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
HFD2_k127_5669868_8 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 407.0
HFD2_k127_5669868_9 Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 392.0
HFD2_k127_5786067_0 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 1.05e-262 838.0
HFD2_k127_5786067_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 568.0
HFD2_k127_5786067_10 carbamoyl transferase, NodU family K00612 - - 0.00000000000000005005 82.0
HFD2_k127_5786067_11 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000004617 50.0
HFD2_k127_5786067_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0003644 52.0
HFD2_k127_5786067_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 512.0
HFD2_k127_5786067_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 496.0
HFD2_k127_5786067_4 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 451.0
HFD2_k127_5786067_5 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 398.0
HFD2_k127_5786067_6 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 299.0
HFD2_k127_5786067_7 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 286.0
HFD2_k127_5786067_8 Squalene phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000002961 150.0
HFD2_k127_5786067_9 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000002941 130.0
HFD2_k127_5795115_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1146.0
HFD2_k127_5795115_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 K15781 - 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 607.0
HFD2_k127_5795115_10 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 387.0
HFD2_k127_5795115_11 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 372.0
HFD2_k127_5795115_12 Proline racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 365.0
HFD2_k127_5795115_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 357.0
HFD2_k127_5795115_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 365.0
HFD2_k127_5795115_15 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 335.0
HFD2_k127_5795115_16 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 336.0
HFD2_k127_5795115_17 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 303.0
HFD2_k127_5795115_19 ABC transporter, ATP-binding protein K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 310.0
HFD2_k127_5795115_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 513.0
HFD2_k127_5795115_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
HFD2_k127_5795115_21 D-amino acid K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000009097 257.0
HFD2_k127_5795115_22 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002669 223.0
HFD2_k127_5795115_23 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000001282 207.0
HFD2_k127_5795115_24 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000003189 190.0
HFD2_k127_5795115_25 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000002215 187.0
HFD2_k127_5795115_26 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000000005595 169.0
HFD2_k127_5795115_27 - - - - 0.000000000000000000000000000000000000001238 153.0
HFD2_k127_5795115_28 EamA-like transporter family - - - 0.0000000000000000000000005362 115.0
HFD2_k127_5795115_29 Putative stress-induced transcription regulator - - - 0.000001027 55.0
HFD2_k127_5795115_3 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 497.0
HFD2_k127_5795115_4 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 468.0
HFD2_k127_5795115_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 451.0
HFD2_k127_5795115_6 xylulose kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 438.0
HFD2_k127_5795115_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
HFD2_k127_5795115_8 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 412.0
HFD2_k127_5795115_9 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 411.0
HFD2_k127_5801526_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 1.312e-310 975.0
HFD2_k127_5801526_1 Carboxyl transferase domain - - - 8.409e-247 788.0
HFD2_k127_5801526_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 375.0
HFD2_k127_5801526_11 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 353.0
HFD2_k127_5801526_12 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 336.0
HFD2_k127_5801526_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 330.0
HFD2_k127_5801526_14 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
HFD2_k127_5801526_15 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 306.0
HFD2_k127_5801526_16 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 301.0
HFD2_k127_5801526_17 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007784 287.0
HFD2_k127_5801526_18 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000046 276.0
HFD2_k127_5801526_19 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 265.0
HFD2_k127_5801526_2 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 4.702e-244 770.0
HFD2_k127_5801526_20 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001118 212.0
HFD2_k127_5801526_21 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002739 202.0
HFD2_k127_5801526_22 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000000000002811 198.0
HFD2_k127_5801526_23 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000005792 149.0
HFD2_k127_5801526_24 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000001081 133.0
HFD2_k127_5801526_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000003777 118.0
HFD2_k127_5801526_26 PFAM regulatory protein, MarR - - - 0.000000000000000000000008988 106.0
HFD2_k127_5801526_27 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000002443 98.0
HFD2_k127_5801526_28 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000135 110.0
HFD2_k127_5801526_29 - - - - 0.00000000000000001615 91.0
HFD2_k127_5801526_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.4e-236 736.0
HFD2_k127_5801526_4 Acyl transferase domain K00645 - 2.3.1.39 9.472e-199 624.0
HFD2_k127_5801526_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.17e-198 622.0
HFD2_k127_5801526_6 Acetyl propionyl-CoA carboxylase, alpha subunit K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 601.0
HFD2_k127_5801526_7 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 506.0
HFD2_k127_5801526_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 430.0
HFD2_k127_5801526_9 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 416.0
HFD2_k127_5885453_0 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
HFD2_k127_5885453_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 413.0
HFD2_k127_5885453_2 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
HFD2_k127_5885453_3 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 329.0
HFD2_k127_5885453_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
HFD2_k127_5885453_5 endonuclease activity - - - 0.00000000000000000000000000000000001111 144.0
HFD2_k127_5885453_6 PFAM Xylose K03335 - 4.2.1.44 0.00000000000000000000000002823 110.0
HFD2_k127_5885453_7 - - - - 0.000000000000000000002107 106.0
HFD2_k127_5885453_8 - - - - 0.000008774 50.0
HFD2_k127_5886880_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 604.0
HFD2_k127_5886880_1 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 452.0
HFD2_k127_5886880_2 ABC-type dipeptide transport system K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 343.0
HFD2_k127_5886880_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000252 233.0
HFD2_k127_5886880_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000001942 201.0
HFD2_k127_5916291_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1210.0
HFD2_k127_5916291_1 FAD dependent oxidoreductase central domain - - - 7.326e-283 892.0
HFD2_k127_5916291_10 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 425.0
HFD2_k127_5916291_11 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 420.0
HFD2_k127_5916291_12 ABC transporter K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 407.0
HFD2_k127_5916291_13 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 406.0
HFD2_k127_5916291_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 375.0
HFD2_k127_5916291_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 341.0
HFD2_k127_5916291_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
HFD2_k127_5916291_17 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 331.0
HFD2_k127_5916291_18 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 315.0
HFD2_k127_5916291_19 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002489 298.0
HFD2_k127_5916291_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 1.491e-230 734.0
HFD2_k127_5916291_20 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000122 277.0
HFD2_k127_5916291_21 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000206 269.0
HFD2_k127_5916291_22 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004409 267.0
HFD2_k127_5916291_23 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
HFD2_k127_5916291_24 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004032 228.0
HFD2_k127_5916291_25 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
HFD2_k127_5916291_26 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000007471 214.0
HFD2_k127_5916291_27 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000001398 186.0
HFD2_k127_5916291_28 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000205 183.0
HFD2_k127_5916291_29 SMART Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000002524 173.0
HFD2_k127_5916291_3 HD domain - - - 1.103e-207 657.0
HFD2_k127_5916291_30 - - - - 0.0000000000000000000000000000000000000000000004596 171.0
HFD2_k127_5916291_31 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000001021 173.0
HFD2_k127_5916291_32 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000003349 176.0
HFD2_k127_5916291_33 transcriptional regulator (MarR - - - 0.0000000000000000000000000000000001396 138.0
HFD2_k127_5916291_34 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000001216 128.0
HFD2_k127_5916291_35 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.0000000000000000000000000000001845 143.0
HFD2_k127_5916291_36 Transcriptional regulator PadR-like family K10917 - - 0.00000000000000000000000000000238 127.0
HFD2_k127_5916291_37 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000003604 128.0
HFD2_k127_5916291_38 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000002121 124.0
HFD2_k127_5916291_39 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.0000000000000000000000006145 118.0
HFD2_k127_5916291_4 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 625.0
HFD2_k127_5916291_40 Domain of unknown function (DU1801) - - - 0.00000000000000000000001185 104.0
HFD2_k127_5916291_42 DUF167 K09131 - - 0.000000000001102 75.0
HFD2_k127_5916291_43 Baseplate assembly protein - - - 0.000000000001642 75.0
HFD2_k127_5916291_44 Baseplate assembly protein - - - 0.00000000008949 70.0
HFD2_k127_5916291_45 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000001955 71.0
HFD2_k127_5916291_46 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000101 61.0
HFD2_k127_5916291_47 Domain of unknown function (DUF4157) K02689,K02690 - - 0.000001519 57.0
HFD2_k127_5916291_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 577.0
HFD2_k127_5916291_6 belongs to the thioredoxin family K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 571.0
HFD2_k127_5916291_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 508.0
HFD2_k127_5916291_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 496.0
HFD2_k127_5916291_9 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 437.0
HFD2_k127_6007214_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1612.0
HFD2_k127_6007214_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1092.0
HFD2_k127_6007214_10 phosphodiesterase - - - 0.00000000000000000000000000000000000000000002413 186.0
HFD2_k127_6007214_11 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000001152 111.0
HFD2_k127_6007214_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
HFD2_k127_6007214_3 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 407.0
HFD2_k127_6007214_4 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 323.0
HFD2_k127_6007214_5 protocatechuate 3,4-dioxygenase, beta subunit' K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
HFD2_k127_6007214_6 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000003787 203.0
HFD2_k127_6007214_7 proteolysis K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000001487 184.0
HFD2_k127_6007214_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000002064 180.0
HFD2_k127_6007214_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000003944 181.0
HFD2_k127_6031502_0 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 409.0
HFD2_k127_6031502_1 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
HFD2_k127_6031502_2 Fumarylacetoacetate (FAA) hydrolase family K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
HFD2_k127_6031502_3 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 287.0
HFD2_k127_6031502_4 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
HFD2_k127_6031502_5 - - - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
HFD2_k127_6031502_6 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000002286 183.0
HFD2_k127_6031502_7 - - - - 0.0000000000000000000000000000000001034 148.0
HFD2_k127_6031502_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000008847 134.0
HFD2_k127_6031502_9 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00001266 56.0
HFD2_k127_6049142_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 606.0
HFD2_k127_6049142_1 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 579.0
HFD2_k127_6049142_10 Ferric uptake regulator family K22297 - - 0.00000000000000000000000000000005799 131.0
HFD2_k127_6049142_11 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000006593 111.0
HFD2_k127_6049142_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 467.0
HFD2_k127_6049142_3 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 479.0
HFD2_k127_6049142_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 410.0
HFD2_k127_6049142_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 342.0
HFD2_k127_6049142_6 COG1592 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000002461 233.0
HFD2_k127_6049142_7 GHMP kinases N terminal domain K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000003032 229.0
HFD2_k127_6049142_8 RNA-binding protein containing a PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000113 223.0
HFD2_k127_6049142_9 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000374 199.0
HFD2_k127_6053922_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.848e-206 649.0
HFD2_k127_6053922_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000002039 218.0
HFD2_k127_6053922_2 His Kinase A (phosphoacceptor) domain K07655 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000008254 206.0
HFD2_k127_6155144_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 484.0
HFD2_k127_6155144_1 PFAM Protein kinase domain K02486 - 2.7.13.3 0.0000004142 59.0
HFD2_k127_6164925_0 Uncharacterized protein family (UPF0051) K09014 - - 4.541e-212 664.0
HFD2_k127_6164925_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.246e-200 632.0
HFD2_k127_6164925_10 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000000005105 116.0
HFD2_k127_6164925_11 Short C-terminal domain K08982 - - 0.0002776 49.0
HFD2_k127_6164925_2 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
HFD2_k127_6164925_3 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
HFD2_k127_6164925_4 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001398 251.0
HFD2_k127_6164925_5 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000000000002134 218.0
HFD2_k127_6164925_6 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000001922 209.0
HFD2_k127_6164925_7 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.000000000000000000000000000000000000000000000000000005006 204.0
HFD2_k127_6164925_8 - - - - 0.000000000000000000000000000000000000000002166 159.0
HFD2_k127_6164925_9 Family of unknown function (DUF5317) - - - 0.00000000000000000000000000000000000000008221 157.0
HFD2_k127_6169548_0 Phage tail sheath C-terminal domain K06907 - - 1.613e-243 761.0
HFD2_k127_6169548_1 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003973 275.0
HFD2_k127_6169548_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
HFD2_k127_6169548_3 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HFD2_k127_6169548_4 Protein of unknown function (DUF4255) - - - 0.0000000000000000001487 104.0
HFD2_k127_6169548_5 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000002512 104.0
HFD2_k127_6169548_6 Belongs to the peptidase S8 family - - - 0.000000002402 71.0
HFD2_k127_6169548_7 - - - - 0.0001273 45.0
HFD2_k127_6170408_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1243.0
HFD2_k127_6170408_1 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.0 1235.0
HFD2_k127_6170408_10 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000001815 196.0
HFD2_k127_6170408_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000007693 185.0
HFD2_k127_6170408_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001914 183.0
HFD2_k127_6170408_13 glyoxalase III activity - - - 0.0000000000000000000000000000000000000264 155.0
HFD2_k127_6170408_14 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000001275 110.0
HFD2_k127_6170408_15 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000001196 68.0
HFD2_k127_6170408_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.382e-238 747.0
HFD2_k127_6170408_3 Dehydrogenase K00467 - 1.13.12.4 1.654e-200 631.0
HFD2_k127_6170408_4 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 387.0
HFD2_k127_6170408_5 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844 274.0
HFD2_k127_6170408_6 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 273.0
HFD2_k127_6170408_7 PFAM Uracil-DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
HFD2_k127_6170408_8 Ferric uptake regulator family K22297 - - 0.00000000000000000000000000000000000000000000000000000009264 202.0
HFD2_k127_6170408_9 transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000008127 201.0
HFD2_k127_6195210_0 Peptidoglycan-binding domain 1 protein - - - 0.0 1673.0
HFD2_k127_6195210_1 Salmonella virulence plasmid 28.1kDa A protein - - - 0.0 1457.0
HFD2_k127_6195210_10 Domain of unknown function (DUF4157) - - - 0.0000000000003311 79.0
HFD2_k127_6195210_11 - - - - 0.00000002989 65.0
HFD2_k127_6195210_12 Methyltransferase - - - 0.0004316 51.0
HFD2_k127_6195210_2 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.163e-209 697.0
HFD2_k127_6195210_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000483 207.0
HFD2_k127_6195210_4 membrane K13277,K15125,K15539 - - 0.0000000000000000000000000000000000000000000000000000001341 226.0
HFD2_k127_6195210_5 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000002065 201.0
HFD2_k127_6195210_6 Belongs to the TPP enzyme family - - - 0.000000000000000000000000000000000000000000000005753 201.0
HFD2_k127_6195210_7 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000005772 141.0
HFD2_k127_6195210_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000004687 100.0
HFD2_k127_6195210_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000005369 94.0
HFD2_k127_6323762_0 PA domain - - - 8.618e-305 967.0
HFD2_k127_6323762_1 Polysaccharide biosynthesis C-terminal domain K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 493.0
HFD2_k127_6323762_2 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 467.0
HFD2_k127_6323762_3 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 265.0
HFD2_k127_6323762_4 - - - - 0.0000000000000000000000000000000000009176 147.0
HFD2_k127_6323762_5 - - - - 0.00000000000000000003399 97.0
HFD2_k127_6342763_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 450.0
HFD2_k127_6342763_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 350.0
HFD2_k127_6342763_2 NAD(P)-dependent K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004874 277.0
HFD2_k127_6342763_3 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007444 281.0
HFD2_k127_6342763_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000006517 209.0
HFD2_k127_6342763_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001198 192.0
HFD2_k127_6342763_6 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000001837 193.0
HFD2_k127_6342763_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003337 150.0
HFD2_k127_6343479_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1617.0
HFD2_k127_6343479_1 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0 1324.0
HFD2_k127_6343479_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 422.0
HFD2_k127_6343479_11 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 433.0
HFD2_k127_6343479_12 glycine betaine K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
HFD2_k127_6343479_13 ABC-type proline glycine betaine transport system permease component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 424.0
HFD2_k127_6343479_14 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 375.0
HFD2_k127_6343479_15 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 364.0
HFD2_k127_6343479_16 Electron transfer flavoprotein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001223 286.0
HFD2_k127_6343479_17 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007133 304.0
HFD2_k127_6343479_18 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002188 270.0
HFD2_k127_6343479_19 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007761 266.0
HFD2_k127_6343479_2 FAD dependent oxidoreductase K19191 - 1.5.3.19 0.0 1055.0
HFD2_k127_6343479_20 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005612 269.0
HFD2_k127_6343479_21 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000002307 241.0
HFD2_k127_6343479_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HFD2_k127_6343479_23 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000006681 226.0
HFD2_k127_6343479_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000005022 168.0
HFD2_k127_6343479_25 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000006317 166.0
HFD2_k127_6343479_26 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000005227 119.0
HFD2_k127_6343479_27 PFAM Sarcosine oxidase delta subunit heterotetrameric K00304 - 1.5.3.1 0.0000000006282 72.0
HFD2_k127_6343479_3 GMC oxidoreductase K00108 - 1.1.99.1 3.007e-287 890.0
HFD2_k127_6343479_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 1.809e-280 882.0
HFD2_k127_6343479_5 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.342e-279 866.0
HFD2_k127_6343479_6 NADH:flavin oxidoreductase / NADH oxidase family K00219,K21833 - 1.3.1.34 1.046e-275 865.0
HFD2_k127_6343479_7 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 2.541e-214 677.0
HFD2_k127_6343479_8 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 587.0
HFD2_k127_6343479_9 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 453.0
HFD2_k127_6351970_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 530.0
HFD2_k127_6351970_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 415.0
HFD2_k127_6351970_10 CHRD domain - - - 0.0000000000000000009604 97.0
HFD2_k127_6351970_13 TIGRFAM conserved repeat domain - - - 0.0000009986 60.0
HFD2_k127_6351970_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 378.0
HFD2_k127_6351970_3 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 353.0
HFD2_k127_6351970_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004369 251.0
HFD2_k127_6351970_5 - - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
HFD2_k127_6351970_6 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000129 203.0
HFD2_k127_6351970_7 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000001582 124.0
HFD2_k127_6351970_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000008567 106.0
HFD2_k127_6351970_9 -acetyltransferase - - - 0.0000000000000000006836 97.0
HFD2_k127_6360827_0 Dehydratase family K01687 - 4.2.1.9 6.264e-302 932.0
HFD2_k127_6360827_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 437.0
HFD2_k127_6360827_2 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 434.0
HFD2_k127_6360827_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 377.0
HFD2_k127_6360827_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000001122 205.0
HFD2_k127_6360827_5 Protein of unknown function (DUF3054) - - - 0.0000000000000000000000000002532 127.0
HFD2_k127_6360827_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000001005 113.0
HFD2_k127_6360827_7 ThiS family - - - 0.000000000000000007392 88.0
HFD2_k127_6360827_8 - - - - 0.00002753 52.0
HFD2_k127_6504788_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.41e-279 868.0
HFD2_k127_6504788_1 glutamine synthetase K01915 - 6.3.1.2 7.274e-229 715.0
HFD2_k127_6504788_10 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 472.0
HFD2_k127_6504788_11 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 415.0
HFD2_k127_6504788_12 Belongs to the Glu Leu Phe Val dehydrogenases family K00270 - 1.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
HFD2_k127_6504788_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 376.0
HFD2_k127_6504788_14 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 311.0
HFD2_k127_6504788_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 292.0
HFD2_k127_6504788_16 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003162 266.0
HFD2_k127_6504788_17 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
HFD2_k127_6504788_18 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000002966 226.0
HFD2_k127_6504788_19 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000001421 241.0
HFD2_k127_6504788_2 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 4.784e-228 725.0
HFD2_k127_6504788_20 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000006342 213.0
HFD2_k127_6504788_21 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000000000000000000000002346 205.0
HFD2_k127_6504788_22 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.00000000000000000000000000000000000000000000000006551 201.0
HFD2_k127_6504788_23 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000000000000000000001911 165.0
HFD2_k127_6504788_24 PFAM periplasmic binding protein LacI transcriptional regulator K03604,K05499 - - 0.000000000000000000000000000000000000001152 160.0
HFD2_k127_6504788_25 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000000000000001084 147.0
HFD2_k127_6504788_26 - - - - 0.0000000000000000000000000000000000816 145.0
HFD2_k127_6504788_27 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000004655 141.0
HFD2_k127_6504788_28 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000002842 138.0
HFD2_k127_6504788_29 membrane - - - 0.0000000000000000000000000000001312 134.0
HFD2_k127_6504788_3 Amidohydrolase family - - - 8.643e-228 711.0
HFD2_k127_6504788_30 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000006547 128.0
HFD2_k127_6504788_31 Acyltransferase - - - 0.0000004643 60.0
HFD2_k127_6504788_32 polysaccharide deacetylase - - - 0.00002083 57.0
HFD2_k127_6504788_4 pyrroloquinoline quinone binding - - - 5.609e-204 663.0
HFD2_k127_6504788_5 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 595.0
HFD2_k127_6504788_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 528.0
HFD2_k127_6504788_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
HFD2_k127_6504788_8 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 492.0
HFD2_k127_6504788_9 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 482.0
HFD2_k127_6505017_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1099.0
HFD2_k127_6505017_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 572.0
HFD2_k127_6505017_10 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
HFD2_k127_6505017_11 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000008521 246.0
HFD2_k127_6505017_12 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000613 229.0
HFD2_k127_6505017_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000007524 213.0
HFD2_k127_6505017_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000008089 215.0
HFD2_k127_6505017_15 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001129 229.0
HFD2_k127_6505017_16 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000005273 185.0
HFD2_k127_6505017_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000004491 172.0
HFD2_k127_6505017_18 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000006789 96.0
HFD2_k127_6505017_19 PFAM LemA family protein K03744 - - 0.0000001811 53.0
HFD2_k127_6505017_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 522.0
HFD2_k127_6505017_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 509.0
HFD2_k127_6505017_4 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 466.0
HFD2_k127_6505017_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 421.0
HFD2_k127_6505017_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 380.0
HFD2_k127_6505017_7 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 363.0
HFD2_k127_6505017_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 362.0
HFD2_k127_6505017_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
HFD2_k127_6535013_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1771.0
HFD2_k127_6535013_1 Alpha-amylase domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 597.0
HFD2_k127_6535013_10 Response regulator receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004365 274.0
HFD2_k127_6535013_11 - - - - 0.0000000000000000000000000000000000456 138.0
HFD2_k127_6535013_12 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000001689 115.0
HFD2_k127_6535013_13 AAA domain - - - 0.000004035 51.0
HFD2_k127_6535013_2 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 578.0
HFD2_k127_6535013_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 489.0
HFD2_k127_6535013_4 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 460.0
HFD2_k127_6535013_5 ABC transporter substrate-binding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 437.0
HFD2_k127_6535013_6 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 416.0
HFD2_k127_6535013_7 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 375.0
HFD2_k127_6535013_8 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 379.0
HFD2_k127_6535013_9 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 308.0
HFD2_k127_6546436_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 3.039e-248 780.0
HFD2_k127_6546436_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 464.0
HFD2_k127_6546436_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000004146 178.0
HFD2_k127_6546436_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000001208 162.0
HFD2_k127_6546436_12 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000002667 153.0
HFD2_k127_6546436_13 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000001301 80.0
HFD2_k127_6546436_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 407.0
HFD2_k127_6546436_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
HFD2_k127_6546436_4 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 313.0
HFD2_k127_6546436_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 305.0
HFD2_k127_6546436_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 278.0
HFD2_k127_6546436_7 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001267 251.0
HFD2_k127_6546436_8 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000005065 229.0
HFD2_k127_6546436_9 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002686 231.0
HFD2_k127_6597949_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 5.019e-214 679.0
HFD2_k127_6597949_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 533.0
HFD2_k127_6597949_10 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000008164 127.0
HFD2_k127_6597949_11 NMT1-like family - - - 0.0000000000000000000000000001902 130.0
HFD2_k127_6597949_13 Cytochrome c - - - 0.0000000009862 64.0
HFD2_k127_6597949_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00005724 46.0
HFD2_k127_6597949_2 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 452.0
HFD2_k127_6597949_3 PFAM Transposase, IS116 IS110 IS902 K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 384.0
HFD2_k127_6597949_4 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
HFD2_k127_6597949_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 295.0
HFD2_k127_6597949_6 neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001305 285.0
HFD2_k127_6597949_7 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 263.0
HFD2_k127_6597949_8 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000002067 193.0
HFD2_k127_6597949_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001125 177.0
HFD2_k127_6709495_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1260.0
HFD2_k127_6709495_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.564e-198 626.0
HFD2_k127_6709495_10 type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 288.0
HFD2_k127_6709495_11 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008177 261.0
HFD2_k127_6709495_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
HFD2_k127_6709495_13 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000006886 234.0
HFD2_k127_6709495_14 Pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000001465 214.0
HFD2_k127_6709495_15 - - - - 0.000000000000000000000000000007768 128.0
HFD2_k127_6709495_16 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000002452 130.0
HFD2_k127_6709495_17 PFAM TadE family protein - - - 0.000000000000000003612 88.0
HFD2_k127_6709495_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000002271 89.0
HFD2_k127_6709495_19 Belongs to the anti-sigma-factor antagonist family - - - 0.0000003609 56.0
HFD2_k127_6709495_2 MMPL family K06994 - - 7.671e-195 633.0
HFD2_k127_6709495_20 Type ii secretion system K12510 - - 0.0000007886 62.0
HFD2_k127_6709495_21 - - - - 0.000186 48.0
HFD2_k127_6709495_22 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins K15532 - 3.2.1.172 0.0001884 53.0
HFD2_k127_6709495_23 Helix-turn-helix domain - - - 0.0005687 47.0
HFD2_k127_6709495_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 6.317e-194 611.0
HFD2_k127_6709495_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 490.0
HFD2_k127_6709495_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 420.0
HFD2_k127_6709495_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 436.0
HFD2_k127_6709495_7 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 385.0
HFD2_k127_6709495_8 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 335.0
HFD2_k127_6709495_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 318.0
HFD2_k127_6773921_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 1.249e-308 962.0
HFD2_k127_6773921_1 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 1.438e-262 820.0
HFD2_k127_6773921_10 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000002478 201.0
HFD2_k127_6773921_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000008313 190.0
HFD2_k127_6773921_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000006477 167.0
HFD2_k127_6773921_14 - - - - 0.000000000000000000000000001748 123.0
HFD2_k127_6773921_15 Protein of unknown function (DUF983) - - - 0.000000000000000000000002649 107.0
HFD2_k127_6773921_16 LysM domain - - - 0.000001029 57.0
HFD2_k127_6773921_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 9.065e-238 742.0
HFD2_k127_6773921_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.886e-195 617.0
HFD2_k127_6773921_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 491.0
HFD2_k127_6773921_5 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 434.0
HFD2_k127_6773921_6 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 437.0
HFD2_k127_6773921_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 342.0
HFD2_k127_6773921_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 312.0
HFD2_k127_6773921_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000008299 251.0
HFD2_k127_6830529_0 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 537.0
HFD2_k127_6830529_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 496.0
HFD2_k127_6830529_10 overlaps another CDS with the same product name - - - 0.0000000000000000000000000004101 129.0
HFD2_k127_6830529_11 - - - - 0.000000000000000000000000003905 121.0
HFD2_k127_6830529_12 cellulose binding - - - 0.000000000000007514 87.0
HFD2_k127_6830529_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000008864 68.0
HFD2_k127_6830529_14 dioxygenase activity - - - 0.000000000805 70.0
HFD2_k127_6830529_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 381.0
HFD2_k127_6830529_3 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003928 277.0
HFD2_k127_6830529_4 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000000009535 251.0
HFD2_k127_6830529_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000006262 158.0
HFD2_k127_6830529_6 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.000000000000000000000000000000000000009111 151.0
HFD2_k127_6830529_7 PFAM aldo keto reductase - - - 0.00000000000000000000000000000001632 140.0
HFD2_k127_6830529_8 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000003086 141.0
HFD2_k127_6839827_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 5e-324 1014.0
HFD2_k127_6839827_1 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 8.166e-274 856.0
HFD2_k127_6839827_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003361 271.0
HFD2_k127_6839827_11 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007684 253.0
HFD2_k127_6839827_12 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000001466 173.0
HFD2_k127_6839827_13 COGs COG0300 Short-chain dehydrogenase of various substrate specificities - - - 0.0000000000000000000000000000000000004785 150.0
HFD2_k127_6839827_14 - - - - 0.000000000000000000000000000000003941 132.0
HFD2_k127_6839827_15 lactoylglutathione lyase activity - - - 0.000000000000000000004698 97.0
HFD2_k127_6839827_16 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000000001796 95.0
HFD2_k127_6839827_17 Alpha/beta hydrolase family - - - 0.0000000000000001481 79.0
HFD2_k127_6839827_18 Copper binding proteins, plastocyanin/azurin family - - - 0.0000682 52.0
HFD2_k127_6839827_19 antisigma factor binding - - - 0.0009318 47.0
HFD2_k127_6839827_2 Phosphoesterase family - - - 7.227e-233 736.0
HFD2_k127_6839827_3 Aldehyde dehydrogenase K00128,K22187 - 1.2.1.3 7.683e-195 630.0
HFD2_k127_6839827_4 Flavin containing amine oxidoreductase - - - 4.487e-194 619.0
HFD2_k127_6839827_5 The glycine cleavage system catalyzes the degradation of glycine K00605,K15066 - 2.1.1.341,2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 519.0
HFD2_k127_6839827_6 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 442.0
HFD2_k127_6839827_7 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 430.0
HFD2_k127_6839827_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
HFD2_k127_6839827_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005816 273.0
HFD2_k127_6847288_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 562.0
HFD2_k127_6847288_1 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 492.0
HFD2_k127_6847288_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 420.0
HFD2_k127_6847288_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002247 228.0
HFD2_k127_6847288_4 Sulfatase - - - 0.00000000000000000000000000000001471 132.0
HFD2_k127_6847288_5 Activator of hsp90 atpase 1 family protein - - - 0.0000000000000000000000000000001184 142.0
HFD2_k127_6863538_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 428.0
HFD2_k127_6863538_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000003049 212.0
HFD2_k127_6863538_2 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000005143 191.0
HFD2_k127_6863538_3 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.00000000000000000000000000000000000000000000000007027 186.0
HFD2_k127_6863538_4 AzlC protein - - - 0.000000000000000000000000003404 121.0
HFD2_k127_7018591_0 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1037.0
HFD2_k127_7018591_1 ABC transporter ATPase permease K06147 - - 9.151e-256 800.0
HFD2_k127_7018591_10 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001826 298.0
HFD2_k127_7018591_11 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001428 241.0
HFD2_k127_7018591_12 Belongs to the peptidase S8 family K01173 - - 0.000000000000000000000000000000000000000000000000000000000000006724 239.0
HFD2_k127_7018591_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000001138 208.0
HFD2_k127_7018591_14 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000002486 208.0
HFD2_k127_7018591_15 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000873 187.0
HFD2_k127_7018591_16 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000009038 183.0
HFD2_k127_7018591_17 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000001753 139.0
HFD2_k127_7018591_18 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000007456 111.0
HFD2_k127_7018591_19 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000004963 118.0
HFD2_k127_7018591_2 Domain of unknown function (DUF4445) - - - 7.035e-231 732.0
HFD2_k127_7018591_20 PFAM peptidase M10A and M12B, matrixin and adamalysin - - - 0.00000000000000000004963 105.0
HFD2_k127_7018591_21 transcriptional regulator - - - 0.0000000000000000001375 96.0
HFD2_k127_7018591_22 Virulence factor - - - 0.0000000003748 71.0
HFD2_k127_7018591_3 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 1.806e-226 718.0
HFD2_k127_7018591_4 Trimethylamine methyltransferase (MTTB) - - - 7.055e-216 709.0
HFD2_k127_7018591_5 Trimethylamine methyltransferase (MTTB) - - - 3.69e-201 639.0
HFD2_k127_7018591_6 mandelate racemase muconate lactonizing K01856 - 5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 505.0
HFD2_k127_7018591_7 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 469.0
HFD2_k127_7018591_8 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 447.0
HFD2_k127_7018591_9 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 387.0
HFD2_k127_70343_0 Non-essential cell division protein that could be required for efficient cell constriction - - - 4.991e-257 835.0
HFD2_k127_70343_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 559.0
HFD2_k127_70343_10 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001277 201.0
HFD2_k127_70343_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000007173 108.0
HFD2_k127_70343_12 Nuclease-related domain - - - 0.000000000000000000005455 106.0
HFD2_k127_70343_13 RNA polymerase II transcriptional preinitiation complex assembly - - - 0.000000002463 69.0
HFD2_k127_70343_14 - - - - 0.0000002285 57.0
HFD2_k127_70343_15 Hemerythrin HHE cation binding domain - - - 0.00003292 49.0
HFD2_k127_70343_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 557.0
HFD2_k127_70343_3 PFAM zinc finger SWIM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 544.0
HFD2_k127_70343_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
HFD2_k127_70343_5 VWA containing CoxE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 470.0
HFD2_k127_70343_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 423.0
HFD2_k127_70343_7 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 374.0
HFD2_k127_70343_8 Nuclease-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
HFD2_k127_70343_9 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004664 248.0
HFD2_k127_7059966_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1157.0
HFD2_k127_7059966_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 540.0
HFD2_k127_7059966_2 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 406.0
HFD2_k127_7059966_3 SnoaL-like polyketide cyclase K15945 - - 0.000000000000000000000000000000000000000000000000008478 185.0
HFD2_k127_7059966_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000001798 156.0
HFD2_k127_7059966_5 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000001255 123.0
HFD2_k127_7059966_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000001627 82.0
HFD2_k127_7089815_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 9.18e-220 687.0
HFD2_k127_7089815_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 619.0
HFD2_k127_7089815_2 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 584.0
HFD2_k127_7089815_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 530.0
HFD2_k127_7089815_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 512.0
HFD2_k127_7089815_5 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 403.0
HFD2_k127_7089815_6 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002114 280.0
HFD2_k127_7089815_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000004582 253.0
HFD2_k127_7089815_8 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000001029 167.0
HFD2_k127_7089815_9 ACT domain K01653 - 2.2.1.6 0.0000000000004475 69.0
HFD2_k127_7097712_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 6.084e-289 908.0
HFD2_k127_7097712_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 1.623e-275 885.0
HFD2_k127_7097712_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 477.0
HFD2_k127_7097712_3 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 441.0
HFD2_k127_7097712_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
HFD2_k127_7097712_5 AzlC protein - - - 0.00000000000000000000000000000000000000003209 172.0
HFD2_k127_7097712_6 NifU-like domain - - - 0.0000000000000000000000000002069 117.0
HFD2_k127_7097712_7 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000001811 75.0
HFD2_k127_7133041_0 Uncharacterised protein family (UPF0182) K09118 - - 3.251e-277 893.0
HFD2_k127_7133041_1 regulation of cell shape K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 497.0
HFD2_k127_7133041_11 - - - - 0.00000001684 62.0
HFD2_k127_7133041_12 - - - - 0.00000009259 56.0
HFD2_k127_7133041_2 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 385.0
HFD2_k127_7133041_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
HFD2_k127_7133041_4 DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
HFD2_k127_7133041_5 Belongs to the peptidase S16 family K07177 - - 0.00000000000000000000000000000000000000000000000000000000000000000755 246.0
HFD2_k127_7133041_6 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000366 208.0
HFD2_k127_7133041_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004953 169.0
HFD2_k127_7133041_8 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000008892 173.0
HFD2_k127_7133041_9 nuclear chromosome segregation K19765 - - 0.00000000000000002262 95.0
HFD2_k127_7152079_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 578.0
HFD2_k127_7152079_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 554.0
HFD2_k127_7152079_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000517 175.0
HFD2_k127_7152079_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000002826 174.0
HFD2_k127_7152079_12 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000007639 162.0
HFD2_k127_7152079_13 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000006027 158.0
HFD2_k127_7152079_16 CcmB protein K02194 - - 0.00000000000000000000000000000002769 127.0
HFD2_k127_7152079_17 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000001127 139.0
HFD2_k127_7152079_18 Protein of unknown function (DUF3107) - - - 0.000000000000000000001665 98.0
HFD2_k127_7152079_19 protein kinase activity - - - 0.00000000000000000002221 94.0
HFD2_k127_7152079_2 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 511.0
HFD2_k127_7152079_3 Transcriptional regulator - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 381.0
HFD2_k127_7152079_4 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 309.0
HFD2_k127_7152079_5 DJ-1 PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 301.0
HFD2_k127_7152079_6 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001255 250.0
HFD2_k127_7152079_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008961 233.0
HFD2_k127_7152079_8 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000001517 221.0
HFD2_k127_7152079_9 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000000000000000000853 179.0
HFD2_k127_7157271_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1410.0
HFD2_k127_7157271_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.006e-317 980.0
HFD2_k127_7157271_10 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 459.0
HFD2_k127_7157271_11 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 434.0
HFD2_k127_7157271_12 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 421.0
HFD2_k127_7157271_13 ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 396.0
HFD2_k127_7157271_14 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 398.0
HFD2_k127_7157271_15 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HFD2_k127_7157271_16 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 386.0
HFD2_k127_7157271_17 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 369.0
HFD2_k127_7157271_18 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 350.0
HFD2_k127_7157271_19 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 329.0
HFD2_k127_7157271_2 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 1.622e-261 861.0
HFD2_k127_7157271_20 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 329.0
HFD2_k127_7157271_21 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 310.0
HFD2_k127_7157271_22 Tetratricopeptide repeat K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 309.0
HFD2_k127_7157271_23 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 296.0
HFD2_k127_7157271_24 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
HFD2_k127_7157271_25 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000001647 186.0
HFD2_k127_7157271_26 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000009747 188.0
HFD2_k127_7157271_27 Competence protein ComEA K02237 - - 0.000000000000000000000000000000000000000000000001689 182.0
HFD2_k127_7157271_28 ABC-type antimicrobial peptide transport system, ATPase component K02003,K05685 - - 0.000000000000000000000000000000000000000000001629 173.0
HFD2_k127_7157271_29 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000002191 163.0
HFD2_k127_7157271_3 MMPL family K07003 - - 3.321e-194 661.0
HFD2_k127_7157271_30 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000003338 158.0
HFD2_k127_7157271_31 Major facilitator Superfamily - - - 0.0000000000000000000000000000000003639 139.0
HFD2_k127_7157271_32 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000007632 141.0
HFD2_k127_7157271_33 polysaccharide deacetylase K15531 - 3.2.1.156 0.000000000000000000000000000001154 139.0
HFD2_k127_7157271_34 Major facilitator superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000511 133.0
HFD2_k127_7157271_35 Hydrogenase maturation protease K03605 - - 0.0000000000000000000001077 109.0
HFD2_k127_7157271_37 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000005552 83.0
HFD2_k127_7157271_39 Transcriptional regulator - - - 0.0000001956 54.0
HFD2_k127_7157271_4 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 611.0
HFD2_k127_7157271_40 - - - - 0.0006452 48.0
HFD2_k127_7157271_41 Sucrose-6F-phosphate phosphohydrolase - - - 0.0007525 51.0
HFD2_k127_7157271_5 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 571.0
HFD2_k127_7157271_6 Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 548.0
HFD2_k127_7157271_7 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 531.0
HFD2_k127_7157271_8 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 534.0
HFD2_k127_7157271_9 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 510.0
HFD2_k127_7160445_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 426.0
HFD2_k127_7160445_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 304.0
HFD2_k127_7160445_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 291.0
HFD2_k127_7160445_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
HFD2_k127_7160445_4 - - - - 0.0000000000000003247 80.0
HFD2_k127_7160445_5 PFAM transposase, IS4 family protein - - - 0.00000000000002892 75.0
HFD2_k127_7160445_6 RibD C-terminal domain - - - 0.00009889 48.0
HFD2_k127_7163964_0 N-terminal domain of (some) glycogen debranching enzymes - - - 8.848e-255 806.0
HFD2_k127_7163964_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 7.672e-232 721.0
HFD2_k127_7163964_10 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 440.0
HFD2_k127_7163964_11 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 392.0
HFD2_k127_7163964_12 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 419.0
HFD2_k127_7163964_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 379.0
HFD2_k127_7163964_14 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 362.0
HFD2_k127_7163964_15 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
HFD2_k127_7163964_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
HFD2_k127_7163964_17 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
HFD2_k127_7163964_18 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000009884 240.0
HFD2_k127_7163964_19 - - - - 0.000000000000000000000000000000000000000000000000004495 187.0
HFD2_k127_7163964_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.466e-221 692.0
HFD2_k127_7163964_20 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000849 178.0
HFD2_k127_7163964_21 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000009881 183.0
HFD2_k127_7163964_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000001202 178.0
HFD2_k127_7163964_23 transglycosylase - - - 0.000000000000000000000000000000000000000000003989 175.0
HFD2_k127_7163964_24 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000005548 167.0
HFD2_k127_7163964_25 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000001398 152.0
HFD2_k127_7163964_26 - - - - 0.00000000000003672 83.0
HFD2_k127_7163964_27 Cation efflux family - - - 0.000000001192 67.0
HFD2_k127_7163964_3 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 627.0
HFD2_k127_7163964_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 609.0
HFD2_k127_7163964_5 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 593.0
HFD2_k127_7163964_6 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 543.0
HFD2_k127_7163964_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 473.0
HFD2_k127_7163964_8 Oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 467.0
HFD2_k127_7163964_9 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 442.0
HFD2_k127_7182649_0 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 413.0
HFD2_k127_7182649_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 407.0
HFD2_k127_7182649_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 293.0
HFD2_k127_7182649_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
HFD2_k127_7182649_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000001398 220.0
HFD2_k127_7182649_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000004009 80.0
HFD2_k127_7182649_6 - - - - 0.0004972 46.0
HFD2_k127_719085_0 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 579.0
HFD2_k127_719085_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 366.0
HFD2_k127_719085_2 Sigma-70 region 3 K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 354.0
HFD2_k127_719085_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 343.0
HFD2_k127_719085_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 319.0
HFD2_k127_719085_5 Ribosomal protein S2 K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000002024 242.0
HFD2_k127_719085_6 heme binding K08259,K21472 - 3.4.24.75 0.000000000000000000000000000002514 127.0
HFD2_k127_719085_7 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.0000003592 53.0
HFD2_k127_7200512_0 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565 - 1.6.5.3 6.117e-246 779.0
HFD2_k127_7200512_1 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 1.782e-240 752.0
HFD2_k127_7200512_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
HFD2_k127_7200512_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 304.0
HFD2_k127_7200512_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000002424 196.0
HFD2_k127_7200512_13 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000000000000000000000000000000000000006918 187.0
HFD2_k127_7200512_14 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000004505 190.0
HFD2_k127_7200512_15 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000004007 181.0
HFD2_k127_7200512_16 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000001477 176.0
HFD2_k127_7200512_17 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000002039 179.0
HFD2_k127_7200512_18 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000003339 157.0
HFD2_k127_7200512_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000001452 151.0
HFD2_k127_7200512_2 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 1.487e-236 743.0
HFD2_k127_7200512_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000004263 134.0
HFD2_k127_7200512_21 Psort location Cytoplasmic, score - - - 0.00000000003448 74.0
HFD2_k127_7200512_22 HYR domain - - - 0.000000001767 70.0
HFD2_k127_7200512_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.305e-231 719.0
HFD2_k127_7200512_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 586.0
HFD2_k127_7200512_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 551.0
HFD2_k127_7200512_6 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 523.0
HFD2_k127_7200512_7 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 484.0
HFD2_k127_7200512_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 451.0
HFD2_k127_7200512_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 318.0
HFD2_k127_7252655_0 COG1404 Subtilisin-like serine proteases K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 417.0
HFD2_k127_7252655_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 374.0
HFD2_k127_7252655_10 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000009139 100.0
HFD2_k127_7252655_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000001469 90.0
HFD2_k127_7252655_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 333.0
HFD2_k127_7252655_3 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000004666 255.0
HFD2_k127_7252655_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004844 235.0
HFD2_k127_7252655_5 - - - - 0.00000000000000000000000000000000000000000000000000000000003558 232.0
HFD2_k127_7252655_6 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005576 207.0
HFD2_k127_7252655_7 - - - - 0.000000000000000000000000000000000000000000000000000001063 198.0
HFD2_k127_7252655_8 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000227 192.0
HFD2_k127_7252655_9 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000004268 166.0
HFD2_k127_7284693_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 589.0
HFD2_k127_7284693_1 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 457.0
HFD2_k127_7284693_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 309.0
HFD2_k127_7284693_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000002241 169.0
HFD2_k127_7284693_4 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000002192 162.0
HFD2_k127_7284693_5 FR47-like protein - - - 0.00000000000000001332 88.0
HFD2_k127_7284693_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000003225 67.0
HFD2_k127_7305940_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 3.047e-281 884.0
HFD2_k127_7305940_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.682e-278 863.0
HFD2_k127_7305940_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002585 205.0
HFD2_k127_7305940_11 Protein of unknown function (DUF1353) - - - 0.00000000000000000000000000000000000000000000000000000000565 207.0
HFD2_k127_7305940_12 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000002933 192.0
HFD2_k127_7305940_13 PFAM regulatory protein MarR - - - 0.0000000000000000000000000000000000000000000000002601 181.0
HFD2_k127_7305940_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000002358 178.0
HFD2_k127_7305940_15 transcriptional regulator - - - 0.0000000000000000000000004063 114.0
HFD2_k127_7305940_16 - - - - 0.000000000000001575 88.0
HFD2_k127_7305940_17 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000008938 64.0
HFD2_k127_7305940_2 Belongs to the amidase family K01426 - 3.5.1.4 1.801e-219 691.0
HFD2_k127_7305940_3 DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
HFD2_k127_7305940_4 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
HFD2_k127_7305940_5 Protein of unknown function (DUF1349) K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 454.0
HFD2_k127_7305940_6 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 399.0
HFD2_k127_7305940_7 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005941 288.0
HFD2_k127_7305940_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000007704 242.0
HFD2_k127_7305940_9 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004386 253.0
HFD2_k127_731833_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 482.0
HFD2_k127_731833_1 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HFD2_k127_731833_2 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000036 229.0
HFD2_k127_731833_3 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000177 206.0
HFD2_k127_731833_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000001951 148.0
HFD2_k127_731833_5 - - - - 0.00000000000000000000000000000000001934 155.0
HFD2_k127_731833_6 Cell wall hydrolase autolysin K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000000000000000000000000003024 130.0
HFD2_k127_731833_8 AntiSigma factor - - - 0.0000002278 61.0
HFD2_k127_7380556_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1092.0
HFD2_k127_7380556_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.381e-280 892.0
HFD2_k127_7380556_10 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
HFD2_k127_7380556_11 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000008767 212.0
HFD2_k127_7380556_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000001439 147.0
HFD2_k127_7380556_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000004219 127.0
HFD2_k127_7380556_15 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000005354 106.0
HFD2_k127_7380556_16 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000008123 96.0
HFD2_k127_7380556_17 Protein of unknown function (DUF503) K09764 - - 0.000000000000002394 81.0
HFD2_k127_7380556_18 Protein of unknown function (DUF448) K07742 - - 0.0000000002473 66.0
HFD2_k127_7380556_19 Chorismate mutase type II K04092 - 5.4.99.5 0.0000000005397 69.0
HFD2_k127_7380556_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 436.0
HFD2_k127_7380556_20 Domain of unknown function (DUF4440) - - - 0.000000001741 63.0
HFD2_k127_7380556_3 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 375.0
HFD2_k127_7380556_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 347.0
HFD2_k127_7380556_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 341.0
HFD2_k127_7380556_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 342.0
HFD2_k127_7380556_7 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 314.0
HFD2_k127_7380556_8 Polar amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002923 282.0
HFD2_k127_7380556_9 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002435 238.0
HFD2_k127_7389114_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1030.0
HFD2_k127_7389114_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0 1003.0
HFD2_k127_7389114_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000008843 233.0
HFD2_k127_7389114_11 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009888 236.0
HFD2_k127_7389114_12 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000001995 231.0
HFD2_k127_7389114_13 FMN binding - - - 0.000000000000000000000000000000000000000000000008557 175.0
HFD2_k127_7389114_14 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000005734 164.0
HFD2_k127_7389114_15 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000003595 160.0
HFD2_k127_7389114_16 Transcriptional regulator, MarR family - - - 0.00000000000000000000000000000000000003004 148.0
HFD2_k127_7389114_19 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000008599 128.0
HFD2_k127_7389114_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.766e-217 685.0
HFD2_k127_7389114_20 CrcB-like protein, Camphor Resistance (CrcB) K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000938 121.0
HFD2_k127_7389114_21 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000006997 120.0
HFD2_k127_7389114_22 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000001355 102.0
HFD2_k127_7389114_23 Sigma-70 region 2 - - - 0.000000000000002524 83.0
HFD2_k127_7389114_24 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000006215 63.0
HFD2_k127_7389114_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HFD2_k127_7389114_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 531.0
HFD2_k127_7389114_5 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 514.0
HFD2_k127_7389114_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 503.0
HFD2_k127_7389114_7 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 473.0
HFD2_k127_7389114_8 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 391.0
HFD2_k127_7389114_9 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 387.0
HFD2_k127_7417449_0 FAD dependent oxidoreductase - - - 7.262e-205 664.0
HFD2_k127_7417449_1 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 529.0
HFD2_k127_7417449_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 435.0
HFD2_k127_7417449_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 380.0
HFD2_k127_7417449_4 cytosine deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 375.0
HFD2_k127_7417449_5 Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 365.0
HFD2_k127_7417449_6 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
HFD2_k127_7417449_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
HFD2_k127_7417449_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000768 237.0
HFD2_k127_7417449_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000002119 136.0
HFD2_k127_7461663_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1131.0
HFD2_k127_7461663_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.181e-255 809.0
HFD2_k127_7461663_10 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 317.0
HFD2_k127_7461663_11 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 313.0
HFD2_k127_7461663_12 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 297.0
HFD2_k127_7461663_13 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 298.0
HFD2_k127_7461663_14 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004711 263.0
HFD2_k127_7461663_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002616 233.0
HFD2_k127_7461663_16 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000006545 243.0
HFD2_k127_7461663_17 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000004659 119.0
HFD2_k127_7461663_19 - - - - 0.0000000000000000000000003317 115.0
HFD2_k127_7461663_2 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 5.572e-226 746.0
HFD2_k127_7461663_21 Diguanylate cyclase - - - 0.000000000000000006707 97.0
HFD2_k127_7461663_22 - - - - 0.000000000000002261 87.0
HFD2_k127_7461663_23 Heavy-metal-associated domain - - - 0.00000000000002093 77.0
HFD2_k127_7461663_24 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.00000000001806 75.0
HFD2_k127_7461663_25 membrane protein (DUF2078) - - - 0.0000000004379 64.0
HFD2_k127_7461663_26 membrane protein (DUF2078) K08982 - - 0.00000003585 59.0
HFD2_k127_7461663_27 gluconolactonase activity K01053 - 3.1.1.17 0.0000003351 63.0
HFD2_k127_7461663_3 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 561.0
HFD2_k127_7461663_4 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 566.0
HFD2_k127_7461663_5 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 509.0
HFD2_k127_7461663_6 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HFD2_k127_7461663_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 418.0
HFD2_k127_7461663_8 transcriptional regulator K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 330.0
HFD2_k127_7461663_9 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 329.0
HFD2_k127_7488022_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 527.0
HFD2_k127_7488022_1 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 368.0
HFD2_k127_7488022_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000007774 169.0
HFD2_k127_7488022_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000007696 106.0
HFD2_k127_7488022_12 Periplasmic binding protein - - - 0.00000000002376 66.0
HFD2_k127_7488022_13 phosphatase activity K07025 - - 0.00000001497 66.0
HFD2_k127_7488022_2 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 362.0
HFD2_k127_7488022_3 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 315.0
HFD2_k127_7488022_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002481 289.0
HFD2_k127_7488022_5 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 281.0
HFD2_k127_7488022_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004072 259.0
HFD2_k127_7488022_7 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008543 253.0
HFD2_k127_7488022_8 Phosphotransferase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000001408 251.0
HFD2_k127_7488022_9 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
HFD2_k127_7491500_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 552.0
HFD2_k127_7491500_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 549.0
HFD2_k127_7491500_2 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
HFD2_k127_7491500_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 327.0
HFD2_k127_7491500_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000005424 129.0
HFD2_k127_7491500_5 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.000000000000000000005482 100.0
HFD2_k127_7495424_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 569.0
HFD2_k127_7495424_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 317.0
HFD2_k127_7495424_2 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 305.0
HFD2_k127_7495424_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003067 279.0
HFD2_k127_7495424_4 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
HFD2_k127_7495424_5 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000001899 218.0
HFD2_k127_7495424_6 Nucleic acid binding, OB-fold, tRNA - - - 0.00000000003984 72.0
HFD2_k127_7495424_7 Forms part of the polypeptide exit tunnel K02926 - - 0.000000002186 63.0
HFD2_k127_7563793_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 4.117e-213 670.0
HFD2_k127_7563793_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 1.078e-199 633.0
HFD2_k127_7563793_10 Polar amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003216 248.0
HFD2_k127_7563793_11 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000001927 133.0
HFD2_k127_7563793_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000005497 88.0
HFD2_k127_7563793_2 o-methyltransferase K21377 - 2.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 526.0
HFD2_k127_7563793_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 524.0
HFD2_k127_7563793_4 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 505.0
HFD2_k127_7563793_5 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 422.0
HFD2_k127_7563793_6 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 410.0
HFD2_k127_7563793_7 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 379.0
HFD2_k127_7563793_8 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 334.0
HFD2_k127_7563793_9 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003002 248.0
HFD2_k127_7576636_0 Rieske 2Fe-2S K14952 - - 1.084e-219 692.0
HFD2_k127_7576636_10 hydratase K02509 - - 0.000000000000000000000000000000000000000000000000000000000000000006225 233.0
HFD2_k127_7576636_11 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
HFD2_k127_7576636_12 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000002983 193.0
HFD2_k127_7576636_13 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000001057 145.0
HFD2_k127_7576636_14 Redoxin - - - 0.00000000000000000000000000000002823 141.0
HFD2_k127_7576636_15 Required for disulfide bond formation in some proteins K03611 - - 0.00000000000000000000000000002969 126.0
HFD2_k127_7576636_16 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000001017 112.0
HFD2_k127_7576636_17 Protein of unknown function (DUF2510) - - - 0.00000000000000003092 89.0
HFD2_k127_7576636_18 Cyclic nucleotide-binding domain - - - 0.00000000000002675 81.0
HFD2_k127_7576636_2 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 339.0
HFD2_k127_7576636_20 procollagen-lysine 5-dioxygenase activity K00473,K13645,K13646,K13647,K15174 GO:0000003,GO:0000902,GO:0000904,GO:0001666,GO:0001701,GO:0001885,GO:0001886,GO:0002009,GO:0002064,GO:0003006,GO:0003008,GO:0003013,GO:0003018,GO:0003158,GO:0003382,GO:0003674,GO:0003824,GO:0003980,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005794,GO:0005802,GO:0006011,GO:0006082,GO:0006139,GO:0006464,GO:0006486,GO:0006493,GO:0006520,GO:0006575,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007295,GO:0007399,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008194,GO:0008198,GO:0008378,GO:0008475,GO:0008544,GO:0008652,GO:0009058,GO:0009059,GO:0009066,GO:0009067,GO:0009100,GO:0009101,GO:0009225,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016043,GO:0016053,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016757,GO:0016758,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0019842,GO:0019953,GO:0021915,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030198,GO:0030199,GO:0030246,GO:0030323,GO:0030324,GO:0030855,GO:0030867,GO:0031012,GO:0031090,GO:0031406,GO:0031418,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032963,GO:0032964,GO:0032989,GO:0032991,GO:0033036,GO:0033218,GO:0033823,GO:0034641,GO:0034645,GO:0035150,GO:0035250,GO:0035251,GO:0035295,GO:0035296,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042175,GO:0042221,GO:0042277,GO:0042311,GO:0042398,GO:0042802,GO:0042803,GO:0043009,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045446,GO:0046394,GO:0046483,GO:0046527,GO:0046872,GO:0046914,GO:0046946,GO:0046947,GO:0046983,GO:0048029,GO:0048037,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048589,GO:0048609,GO:0048729,GO:0048730,GO:0048731,GO:0048856,GO:0048869,GO:0050211,GO:0050662,GO:0050880,GO:0050896,GO:0051179,GO:0051213,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060425,GO:0060429,GO:0060541,GO:0062023,GO:0065007,GO:0065008,GO:0070085,GO:0070482,GO:0070815,GO:0070831,GO:0070887,GO:0071310,GO:0071495,GO:0071704,GO:0071711,GO:0071840,GO:0090066,GO:0097359,GO:0097435,GO:0097746,GO:0097755,GO:0098588,GO:0098791,GO:0098827,GO:0140096,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 1.14.11.4,2.4.1.50,2.4.1.66 0.00000000001978 72.0
HFD2_k127_7576636_21 lipolytic protein G-D-S-L family - - - 0.000000000726 69.0
HFD2_k127_7576636_22 - - - - 0.0004234 51.0
HFD2_k127_7576636_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 331.0
HFD2_k127_7576636_4 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 297.0
HFD2_k127_7576636_5 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003302 296.0
HFD2_k127_7576636_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 271.0
HFD2_k127_7576636_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003926 275.0
HFD2_k127_7576636_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009296 259.0
HFD2_k127_7576636_9 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003047 261.0
HFD2_k127_7667121_0 collagen metabolic process - - - 1.363e-219 713.0
HFD2_k127_7667121_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 392.0
HFD2_k127_7667121_10 Phosphotransferase enzyme family K18844,K18845 - 2.1.1.179 0.0000000000001297 78.0
HFD2_k127_7667121_11 antisigma factor binding K04749,K17763,K20978 - - 0.000000005121 62.0
HFD2_k127_7667121_12 STAS domain - - - 0.00002224 55.0
HFD2_k127_7667121_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
HFD2_k127_7667121_3 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 260.0
HFD2_k127_7667121_4 Dihydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001503 258.0
HFD2_k127_7667121_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
HFD2_k127_7667121_6 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000008426 225.0
HFD2_k127_7667121_7 ANTAR - - - 0.000000000000000000000000000000000000000006751 163.0
HFD2_k127_7667121_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000009731 146.0
HFD2_k127_7667121_9 TfoX N-terminal domain - - - 0.0000000000000000000000000000000000007225 143.0
HFD2_k127_7707812_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 398.0
HFD2_k127_7707812_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 324.0
HFD2_k127_7707812_2 serine-type endopeptidase activity K04771 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 291.0
HFD2_k127_7707812_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001094 271.0
HFD2_k127_7707812_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000001022 175.0
HFD2_k127_7707812_5 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000002834 139.0
HFD2_k127_7707812_6 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000004312 69.0
HFD2_k127_7707812_7 Sortase family K07284 - 3.4.22.70 0.00000005702 64.0
HFD2_k127_77741_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 383.0
HFD2_k127_77741_1 PFAM Inositol monophosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000007482 268.0
HFD2_k127_77741_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000001227 70.0
HFD2_k127_77741_3 Sulfotransferase domain - - - 0.0004082 44.0
HFD2_k127_77741_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000958 45.0
HFD2_k127_7910352_0 homoserine dehydrogenase - - - 2.038e-207 657.0
HFD2_k127_7910352_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 518.0
HFD2_k127_7910352_10 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003101 296.0
HFD2_k127_7910352_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003388 289.0
HFD2_k127_7910352_12 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004946 274.0
HFD2_k127_7910352_13 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002182 249.0
HFD2_k127_7910352_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000191 251.0
HFD2_k127_7910352_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006576 235.0
HFD2_k127_7910352_16 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000001521 210.0
HFD2_k127_7910352_17 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000002928 205.0
HFD2_k127_7910352_18 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.00000000000000000000000000000000000000000000001034 184.0
HFD2_k127_7910352_19 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000001742 162.0
HFD2_k127_7910352_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 445.0
HFD2_k127_7910352_20 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000001431 168.0
HFD2_k127_7910352_21 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000005813 167.0
HFD2_k127_7910352_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000002455 156.0
HFD2_k127_7910352_23 protein tyrosine kinase activity K20998 - - 0.0000000000000000000000000000000000000001487 165.0
HFD2_k127_7910352_24 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.000000000000000000000000000000000000001205 151.0
HFD2_k127_7910352_25 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000003698 138.0
HFD2_k127_7910352_26 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000004696 115.0
HFD2_k127_7910352_28 Transcriptional regulator - - - 0.000000000001483 71.0
HFD2_k127_7910352_29 PFAM Glycosyl transferase family 2 - - - 0.000000000009117 74.0
HFD2_k127_7910352_3 -O-antigen K02847,K02849,K21003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 446.0
HFD2_k127_7910352_30 Psort location CytoplasmicMembrane, score 9.99 - - - 0.0000317 56.0
HFD2_k127_7910352_31 hemerythrin HHE cation binding domain - - - 0.0009685 48.0
HFD2_k127_7910352_4 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 426.0
HFD2_k127_7910352_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 377.0
HFD2_k127_7910352_6 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 367.0
HFD2_k127_7910352_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 368.0
HFD2_k127_7910352_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 331.0
HFD2_k127_7910352_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 301.0
HFD2_k127_797486_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1186.0
HFD2_k127_797486_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 1.699e-310 967.0
HFD2_k127_797486_10 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 412.0
HFD2_k127_797486_11 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 409.0
HFD2_k127_797486_12 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 362.0
HFD2_k127_797486_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 323.0
HFD2_k127_797486_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
HFD2_k127_797486_15 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 322.0
HFD2_k127_797486_16 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 314.0
HFD2_k127_797486_17 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000001497 268.0
HFD2_k127_797486_18 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000001382 238.0
HFD2_k127_797486_19 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000003891 238.0
HFD2_k127_797486_2 Aminotransferase class-V - - - 4.263e-273 849.0
HFD2_k127_797486_20 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002963 213.0
HFD2_k127_797486_21 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000004678 217.0
HFD2_k127_797486_22 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000143 209.0
HFD2_k127_797486_23 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000001108 162.0
HFD2_k127_797486_24 FCD - - - 0.0000000000000000000000000000000000000000003706 170.0
HFD2_k127_797486_25 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000005723 169.0
HFD2_k127_797486_26 Haem-degrading - - - 0.00000000000000000000000000000000000000001253 166.0
HFD2_k127_797486_27 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000001584 164.0
HFD2_k127_797486_28 Dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000003099 164.0
HFD2_k127_797486_29 Family of unknown function (DUF5317) - - - 0.0000000000000000000000000000000000000002608 164.0
HFD2_k127_797486_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 565.0
HFD2_k127_797486_30 Electron transfer flavoprotein, beta subunit FixA family protein K03521 - - 0.0000000000000000000000000000000000000003644 169.0
HFD2_k127_797486_31 FCD - - - 0.0000000000000000000000000000000000000004399 156.0
HFD2_k127_797486_32 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000001452 162.0
HFD2_k127_797486_33 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000187 156.0
HFD2_k127_797486_34 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000005739 123.0
HFD2_k127_797486_35 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000002156 113.0
HFD2_k127_797486_36 Major Facilitator Superfamily K19577 - - 0.000000000008747 77.0
HFD2_k127_797486_37 Phosphotransferase enzyme family - - - 0.00000364 58.0
HFD2_k127_797486_38 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00001808 57.0
HFD2_k127_797486_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 520.0
HFD2_k127_797486_5 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 470.0
HFD2_k127_797486_6 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 440.0
HFD2_k127_797486_7 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 441.0
HFD2_k127_797486_8 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 450.0
HFD2_k127_797486_9 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 423.0
HFD2_k127_7977966_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.959e-203 652.0
HFD2_k127_7977966_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 577.0
HFD2_k127_7977966_10 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000000000000000000000000000000000000003847 192.0
HFD2_k127_7977966_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.0000000000000000000000000000000000000000000000001076 195.0
HFD2_k127_7977966_12 regulation of cell shape - - - 0.00000000000005213 74.0
HFD2_k127_7977966_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 483.0
HFD2_k127_7977966_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 478.0
HFD2_k127_7977966_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 438.0
HFD2_k127_7977966_5 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 395.0
HFD2_k127_7977966_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 361.0
HFD2_k127_7977966_7 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
HFD2_k127_7977966_8 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000355 215.0
HFD2_k127_7977966_9 Alanine racemase, N-terminal domain K06997 - - 0.000000000000000000000000000000000000000000000000000000002662 217.0
HFD2_k127_7995482_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 4.31e-317 1007.0
HFD2_k127_7995482_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.687e-255 795.0
HFD2_k127_7995482_10 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 359.0
HFD2_k127_7995482_11 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 323.0
HFD2_k127_7995482_12 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
HFD2_k127_7995482_13 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
HFD2_k127_7995482_14 Serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 315.0
HFD2_k127_7995482_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 320.0
HFD2_k127_7995482_16 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 322.0
HFD2_k127_7995482_17 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 300.0
HFD2_k127_7995482_18 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 306.0
HFD2_k127_7995482_19 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003887 287.0
HFD2_k127_7995482_2 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 570.0
HFD2_k127_7995482_20 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005596 275.0
HFD2_k127_7995482_21 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003659 261.0
HFD2_k127_7995482_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000003679 234.0
HFD2_k127_7995482_23 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000001991 203.0
HFD2_k127_7995482_24 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000105 197.0
HFD2_k127_7995482_25 Aldo/keto reductase family K18471 - - 0.0000000000000000000000000000000000000000000000001146 188.0
HFD2_k127_7995482_26 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000001675 188.0
HFD2_k127_7995482_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000008434 182.0
HFD2_k127_7995482_28 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000004034 190.0
HFD2_k127_7995482_29 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000007028 154.0
HFD2_k127_7995482_3 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 542.0
HFD2_k127_7995482_30 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000006642 160.0
HFD2_k127_7995482_31 - - - - 0.00000000000000000000000000001341 122.0
HFD2_k127_7995482_32 SnoaL-like domain - - - 0.00000000000000000000000000004739 120.0
HFD2_k127_7995482_33 2-phosphosulpholactate phosphatase K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000007652 120.0
HFD2_k127_7995482_34 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.0000000000000000000002216 106.0
HFD2_k127_7995482_35 sequence-specific DNA binding K07467 - - 0.0000000000000000006543 89.0
HFD2_k127_7995482_36 spore germination - - - 0.000000000000000002648 96.0
HFD2_k127_7995482_39 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000006894 55.0
HFD2_k127_7995482_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 526.0
HFD2_k127_7995482_41 Peptidase C14 caspase catalytic subunit p20 - - - 0.00008835 54.0
HFD2_k127_7995482_42 domain protein - - - 0.0002423 53.0
HFD2_k127_7995482_43 L,D-transpeptidase catalytic domain - - - 0.0005888 50.0
HFD2_k127_7995482_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 521.0
HFD2_k127_7995482_6 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 512.0
HFD2_k127_7995482_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 499.0
HFD2_k127_7995482_8 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 409.0
HFD2_k127_7995482_9 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HFD2_k127_8028024_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.423e-269 846.0
HFD2_k127_8028024_1 protein secretion K20276,K21449 - - 3.924e-219 736.0
HFD2_k127_8028024_10 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.00000000000000000000000000000000000000000002423 183.0
HFD2_k127_8028024_11 - - - - 0.0000000000000007143 85.0
HFD2_k127_8028024_2 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HFD2_k127_8028024_3 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 376.0
HFD2_k127_8028024_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 310.0
HFD2_k127_8028024_5 Rieske 2Fe-2S K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 300.0
HFD2_k127_8028024_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001877 279.0
HFD2_k127_8028024_7 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HFD2_k127_8028024_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000149 181.0
HFD2_k127_8028024_9 - - - - 0.000000000000000000000000000000000000000000003672 179.0
HFD2_k127_8069472_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 552.0
HFD2_k127_8069472_1 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 519.0
HFD2_k127_8069472_10 EamA-like transporter family - - - 0.00000002615 65.0
HFD2_k127_8069472_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 478.0
HFD2_k127_8069472_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 417.0
HFD2_k127_8069472_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
HFD2_k127_8069472_5 Protein of unknown function (DUF971) K00471 - 1.14.11.1 0.0000000000000000000000000000000000000000000000000000000000001774 226.0
HFD2_k127_8069472_6 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004311 232.0
HFD2_k127_8069472_7 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000003795 207.0
HFD2_k127_8069472_8 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000001542 177.0
HFD2_k127_8069472_9 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000007287 178.0
HFD2_k127_8078642_0 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 572.0
HFD2_k127_8078642_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 517.0
HFD2_k127_8078642_10 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000004049 201.0
HFD2_k127_8078642_11 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000000001835 173.0
HFD2_k127_8078642_12 methyltransferase - - - 0.000000000000000000000000000000000000000000405 166.0
HFD2_k127_8078642_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000001983 159.0
HFD2_k127_8078642_14 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000001545 164.0
HFD2_k127_8078642_15 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000002604 164.0
HFD2_k127_8078642_16 PspC domain - - - 0.0000000000000000000000000000000001777 143.0
HFD2_k127_8078642_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000005754 132.0
HFD2_k127_8078642_18 Diguanylate cyclase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - 0.00000000000000000000000388 116.0
HFD2_k127_8078642_2 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 459.0
HFD2_k127_8078642_20 PFAM PspC domain protein - - - 0.000000000000000006431 99.0
HFD2_k127_8078642_22 FR47-like protein - - - 0.000000000000005688 83.0
HFD2_k127_8078642_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 449.0
HFD2_k127_8078642_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 349.0
HFD2_k127_8078642_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 342.0
HFD2_k127_8078642_6 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 332.0
HFD2_k127_8078642_7 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 316.0
HFD2_k127_8078642_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002274 255.0
HFD2_k127_8078642_9 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
HFD2_k127_8095045_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5e-324 1001.0
HFD2_k127_8095045_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 578.0
HFD2_k127_8095045_10 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
HFD2_k127_8095045_11 - - - - 0.000000000000000000000000000000000000000000000000000002181 205.0
HFD2_k127_8095045_12 Cytochrome c biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000003598 207.0
HFD2_k127_8095045_13 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000006119 194.0
HFD2_k127_8095045_14 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000003203 185.0
HFD2_k127_8095045_15 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000005893 153.0
HFD2_k127_8095045_16 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000000000000005325 145.0
HFD2_k127_8095045_17 Redoxin - - - 0.0000000000000000000000000000000000005563 147.0
HFD2_k127_8095045_19 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000004452 113.0
HFD2_k127_8095045_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 491.0
HFD2_k127_8095045_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 451.0
HFD2_k127_8095045_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 399.0
HFD2_k127_8095045_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 346.0
HFD2_k127_8095045_6 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 301.0
HFD2_k127_8095045_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 267.0
HFD2_k127_8095045_8 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007513 263.0
HFD2_k127_8095045_9 Replication protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002711 248.0
HFD2_k127_8198735_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 7.714e-221 692.0
HFD2_k127_8198735_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.753e-197 622.0
HFD2_k127_8198735_10 - - - - 0.0000000000000000000000000000008345 136.0
HFD2_k127_8198735_11 Ethyl tert-butyl ether degradation EthD - - - 0.00000000004796 67.0
HFD2_k127_8198735_12 DNA integration - - - 0.00000108 58.0
HFD2_k127_8198735_14 - - - - 0.000002799 53.0
HFD2_k127_8198735_15 - - - - 0.000007785 58.0
HFD2_k127_8198735_16 - - - - 0.00006152 53.0
HFD2_k127_8198735_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 406.0
HFD2_k127_8198735_3 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 345.0
HFD2_k127_8198735_4 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 314.0
HFD2_k127_8198735_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 302.0
HFD2_k127_8198735_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004707 295.0
HFD2_k127_8198735_7 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001916 224.0
HFD2_k127_8198735_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000006058 216.0
HFD2_k127_8198735_9 - - - - 0.000000000000000000000000000000000000005121 145.0
HFD2_k127_8220958_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 4.501e-232 737.0
HFD2_k127_8220958_1 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 565.0
HFD2_k127_8220958_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 443.0
HFD2_k127_8220958_3 nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 389.0
HFD2_k127_8220958_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 345.0
HFD2_k127_8220958_5 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HFD2_k127_8220958_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002208 235.0
HFD2_k127_8220958_8 Binds the 23S rRNA K02909 - - 0.000000000000000000000007941 101.0
HFD2_k127_8223231_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.376e-295 919.0
HFD2_k127_8223231_1 acyl-CoA dehydrogenase - - - 1.029e-222 703.0
HFD2_k127_8223231_10 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 346.0
HFD2_k127_8223231_11 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 297.0
HFD2_k127_8223231_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
HFD2_k127_8223231_13 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004985 292.0
HFD2_k127_8223231_14 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HFD2_k127_8223231_15 - K09957 - - 0.0000000000000000000000000000000000000000000000000000000000007424 229.0
HFD2_k127_8223231_16 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000002361 210.0
HFD2_k127_8223231_17 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000009029 183.0
HFD2_k127_8223231_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000447 157.0
HFD2_k127_8223231_19 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000008978 136.0
HFD2_k127_8223231_2 Putative modulator of DNA gyrase K03592 - - 7.62e-211 663.0
HFD2_k127_8223231_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000001068 132.0
HFD2_k127_8223231_22 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000004725 133.0
HFD2_k127_8223231_24 Regulatory protein, FmdB family - - - 0.000000000000000000001352 98.0
HFD2_k127_8223231_25 PFAM regulatory protein LuxR - - - 0.0000000000000005206 93.0
HFD2_k127_8223231_26 Serine aminopeptidase, S33 - - - 0.00000000000002474 88.0
HFD2_k127_8223231_27 SnoaL-like domain - - - 0.000000000003758 79.0
HFD2_k127_8223231_28 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000003876 55.0
HFD2_k127_8223231_29 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00005348 53.0
HFD2_k127_8223231_3 Activates fatty acids by binding to coenzyme A K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 557.0
HFD2_k127_8223231_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 494.0
HFD2_k127_8223231_5 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 488.0
HFD2_k127_8223231_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 459.0
HFD2_k127_8223231_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 437.0
HFD2_k127_8223231_8 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 360.0
HFD2_k127_8223231_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 345.0
HFD2_k127_8260049_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 376.0
HFD2_k127_8260049_1 PFAM Glycosyl transferases group 1 K03867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 368.0
HFD2_k127_8260049_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004781 286.0
HFD2_k127_8260049_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006402 217.0
HFD2_k127_8260049_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000169 207.0
HFD2_k127_8260049_5 Glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.000000000000000000000000000000000000000000001527 168.0
HFD2_k127_8260049_6 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000006495 149.0
HFD2_k127_8260049_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000001797 132.0
HFD2_k127_8260049_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000008183 49.0
HFD2_k127_8285037_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 494.0
HFD2_k127_8285037_1 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 349.0
HFD2_k127_8285037_2 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000002171 122.0
HFD2_k127_8285037_3 Transcriptional regulator, LysR family - - - 0.0000000000000000000001066 100.0
HFD2_k127_8285037_4 Alpha/beta hydrolase family - - - 0.000000000000002448 85.0
HFD2_k127_8389893_0 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 527.0
HFD2_k127_8389893_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 445.0
HFD2_k127_8389893_10 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 317.0
HFD2_k127_8389893_11 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
HFD2_k127_8389893_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
HFD2_k127_8389893_13 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
HFD2_k127_8389893_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000153 237.0
HFD2_k127_8389893_15 Domain of unknown function (DUF4188) - - - 0.000000000000000000000000000000000000000000000000000000000000000006313 239.0
HFD2_k127_8389893_16 Domain of unknown function (DUF4280) - - - 0.00000000000000000000000000000000000000000000005396 173.0
HFD2_k127_8389893_17 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000001066 139.0
HFD2_k127_8389893_18 PFAM response regulator receiver K07689 - - 0.00000000000000000000000000000002242 131.0
HFD2_k127_8389893_19 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000218 97.0
HFD2_k127_8389893_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 430.0
HFD2_k127_8389893_20 - - - - 0.000000001448 60.0
HFD2_k127_8389893_3 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 409.0
HFD2_k127_8389893_4 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 397.0
HFD2_k127_8389893_5 PFAM transcriptional regulator domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 389.0
HFD2_k127_8389893_6 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 362.0
HFD2_k127_8389893_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 351.0
HFD2_k127_8389893_8 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 310.0
HFD2_k127_8389893_9 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 303.0
HFD2_k127_8389920_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 8.674e-221 695.0
HFD2_k127_8389920_1 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 502.0
HFD2_k127_8389920_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
HFD2_k127_8389920_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000009341 223.0
HFD2_k127_8389920_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000003722 211.0
HFD2_k127_8389920_5 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000001092 181.0
HFD2_k127_8389920_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000002408 162.0
HFD2_k127_8389920_7 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000002952 156.0
HFD2_k127_8389920_8 - - - - 0.00000000000000000000000000000008613 130.0
HFD2_k127_8389920_9 Multicopper oxidase K00368 - 1.7.2.1 0.0000000001499 71.0
HFD2_k127_8506826_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 507.0
HFD2_k127_8506826_1 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003414 279.0
HFD2_k127_8506826_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000302 143.0
HFD2_k127_8506826_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000007505 125.0
HFD2_k127_8506826_4 translation release factor activity - - - 0.00000000000000000000000001211 123.0
HFD2_k127_8506826_5 Histidine kinase K07711,K19694 - 2.7.13.3 0.000000000000000002834 97.0
HFD2_k127_8506826_6 CBS domains - - - 0.0000000000000007482 83.0
HFD2_k127_8567559_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 1.599e-237 749.0
HFD2_k127_8567559_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 4.387e-220 707.0
HFD2_k127_8567559_10 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
HFD2_k127_8567559_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 402.0
HFD2_k127_8567559_12 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 376.0
HFD2_k127_8567559_13 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 349.0
HFD2_k127_8567559_14 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 310.0
HFD2_k127_8567559_15 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007718 292.0
HFD2_k127_8567559_16 Zinc permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004606 281.0
HFD2_k127_8567559_17 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003116 262.0
HFD2_k127_8567559_18 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001996 233.0
HFD2_k127_8567559_19 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000009393 194.0
HFD2_k127_8567559_2 ClpX C4-type zinc finger K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.424e-206 647.0
HFD2_k127_8567559_20 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000001869 181.0
HFD2_k127_8567559_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001535 157.0
HFD2_k127_8567559_22 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000005902 162.0
HFD2_k127_8567559_23 - K03571 - - 0.00000000000000000000000000000000000006516 149.0
HFD2_k127_8567559_24 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000006321 135.0
HFD2_k127_8567559_26 lactoylglutathione lyase activity - - - 0.00000000000000000000000008996 110.0
HFD2_k127_8567559_27 domain protein - - - 0.0000000000000002725 91.0
HFD2_k127_8567559_28 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000152 82.0
HFD2_k127_8567559_29 Polysaccharide biosynthesis C-terminal domain K03980 - - 0.000000002131 61.0
HFD2_k127_8567559_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.156e-200 656.0
HFD2_k127_8567559_30 Nucleotidyltransferase domain - - - 0.0000001154 60.0
HFD2_k127_8567559_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.775e-200 637.0
HFD2_k127_8567559_5 Cell division protein FtsA K03569 - - 2.486e-199 623.0
HFD2_k127_8567559_6 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 574.0
HFD2_k127_8567559_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 544.0
HFD2_k127_8567559_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 509.0
HFD2_k127_8567559_9 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
HFD2_k127_8605906_0 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 609.0
HFD2_k127_8605906_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 607.0
HFD2_k127_8605906_10 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 263.0
HFD2_k127_8605906_11 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000000005062 255.0
HFD2_k127_8605906_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
HFD2_k127_8605906_13 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000006653 191.0
HFD2_k127_8605906_14 PFAM DsrC family protein K11179 - - 0.000000000000000000000000000000000000000001463 157.0
HFD2_k127_8605906_15 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.0000000000000000000000000000000000000003692 150.0
HFD2_k127_8605906_16 - - - - 0.000000000000000000000001509 107.0
HFD2_k127_8605906_17 Protein of unknown function (DUF4242) - - - 0.000000000000000000000004324 106.0
HFD2_k127_8605906_18 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000003878 81.0
HFD2_k127_8605906_19 prohibitin homologues - - - 0.0000000000005733 82.0
HFD2_k127_8605906_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 582.0
HFD2_k127_8605906_20 NfeD-like C-terminal, partner-binding - - - 0.00009202 51.0
HFD2_k127_8605906_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 487.0
HFD2_k127_8605906_4 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 475.0
HFD2_k127_8605906_5 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 477.0
HFD2_k127_8605906_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 455.0
HFD2_k127_8605906_7 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 436.0
HFD2_k127_8605906_8 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 415.0
HFD2_k127_8605906_9 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 340.0
HFD2_k127_8621696_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 554.0
HFD2_k127_8621696_1 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005618 279.0
HFD2_k127_8621696_2 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000003709 197.0
HFD2_k127_8621696_3 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000003469 185.0
HFD2_k127_8621696_4 transcriptional regulator - - - 0.000000000000000000000000000000000000007365 154.0
HFD2_k127_8704843_0 Elongation factor SelB, winged helix K03833 - - 3.08e-211 672.0
HFD2_k127_8704843_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
HFD2_k127_8704843_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 426.0
HFD2_k127_8704843_3 Belongs to the NUDIX hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
HFD2_k127_8704843_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004354 265.0
HFD2_k127_8704843_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000002156 188.0
HFD2_k127_8704843_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.00000000000000000000000000001911 119.0
HFD2_k127_907378_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.045e-286 890.0
HFD2_k127_907378_1 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 522.0
HFD2_k127_907378_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 532.0
HFD2_k127_907378_3 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 395.0
HFD2_k127_907378_4 ATPases associated with a variety of cellular activities K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 395.0
HFD2_k127_907378_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 305.0
HFD2_k127_907378_6 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000006727 207.0
HFD2_k127_907378_8 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000948 50.0
HFD2_k127_916132_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1276.0
HFD2_k127_916132_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.033e-194 616.0
HFD2_k127_916132_10 LysR substrate binding domain - - - 0.00000001029 61.0
HFD2_k127_916132_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000582 248.0
HFD2_k127_916132_3 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000003909 246.0
HFD2_k127_916132_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000001816 213.0
HFD2_k127_916132_5 protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000007809 194.0
HFD2_k127_916132_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000002111 194.0
HFD2_k127_916132_7 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000006653 137.0
HFD2_k127_916132_8 TM2 domain - - - 0.0000000000000000000000005872 120.0
HFD2_k127_916132_9 FMN_bind - - - 0.000000000000000001589 94.0
HFD2_k127_94212_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1470.0
HFD2_k127_94212_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1023.0
HFD2_k127_94212_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005075 285.0
HFD2_k127_94212_11 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
HFD2_k127_94212_12 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005124 275.0
HFD2_k127_94212_13 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 263.0
HFD2_k127_94212_14 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000001733 220.0
HFD2_k127_94212_15 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000343 185.0
HFD2_k127_94212_16 - - - - 0.00000000000000000000000000000000000000000002707 169.0
HFD2_k127_94212_17 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000001377 157.0
HFD2_k127_94212_19 Ribosomal L28 family K02902 - - 0.00000000000000000000000000004181 117.0
HFD2_k127_94212_2 Hydrolase CocE NonD family K06978 - - 2.529e-214 687.0
HFD2_k127_94212_20 Cold shock K03704 - - 0.000000000000000000000000271 106.0
HFD2_k127_94212_21 - - - - 0.0000000000000000000000003952 113.0
HFD2_k127_94212_22 Fic/DOC family K07341 - - 0.0000000001685 68.0
HFD2_k127_94212_3 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 586.0
HFD2_k127_94212_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 434.0
HFD2_k127_94212_5 Zc3h12a-like Ribonuclease NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 363.0
HFD2_k127_94212_6 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 362.0
HFD2_k127_94212_7 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 319.0
HFD2_k127_94212_8 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
HFD2_k127_94212_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 291.0
HFD2_k127_950217_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.384e-222 698.0
HFD2_k127_950217_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 590.0
HFD2_k127_950217_10 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
HFD2_k127_950217_11 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
HFD2_k127_950217_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000001824 252.0
HFD2_k127_950217_13 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000001594 220.0
HFD2_k127_950217_14 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000006415 199.0
HFD2_k127_950217_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000006626 188.0
HFD2_k127_950217_16 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000003213 175.0
HFD2_k127_950217_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000003624 164.0
HFD2_k127_950217_18 - - - - 0.000000000000000000000000000000000000000004201 165.0
HFD2_k127_950217_19 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000001999 166.0
HFD2_k127_950217_2 Epoxide hydrolase N terminus K21159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 581.0
HFD2_k127_950217_20 Ribosomal protein S16 K02959 - - 0.00000000000000000000000000000000292 130.0
HFD2_k127_950217_21 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000009518 129.0
HFD2_k127_950217_23 nuclease activity K07460 - - 0.0000000000000000000000000002402 119.0
HFD2_k127_950217_24 Protein of unknown function (DUF952) - - - 0.000000000000000000000001499 117.0
HFD2_k127_950217_25 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.00000000000000000000001059 106.0
HFD2_k127_950217_26 - - - - 0.00000000000000000003203 107.0
HFD2_k127_950217_27 - - - - 0.0000000000001413 81.0
HFD2_k127_950217_3 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 555.0
HFD2_k127_950217_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 444.0
HFD2_k127_950217_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
HFD2_k127_950217_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 366.0
HFD2_k127_950217_7 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 344.0
HFD2_k127_950217_8 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 320.0
HFD2_k127_950217_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 307.0
HFD2_k127_954188_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3103.0
HFD2_k127_954188_1 - - - - 0.0 1204.0
HFD2_k127_954188_10 nitric oxide dioxygenase activity K05916 - 1.14.12.17 0.0000000000000000000000004714 116.0
HFD2_k127_954188_11 - - - - 0.000000000000000000002005 96.0
HFD2_k127_954188_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000666 87.0
HFD2_k127_954188_13 - - - - 0.00000000000005657 79.0
HFD2_k127_954188_14 - - - - 0.00000000005596 66.0
HFD2_k127_954188_2 - - - - 0.0 1147.0
HFD2_k127_954188_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 617.0
HFD2_k127_954188_4 alkaline phosphatase K01077,K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 379.0
HFD2_k127_954188_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 243.0
HFD2_k127_954188_6 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000001108 162.0
HFD2_k127_954188_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000226 143.0
HFD2_k127_954188_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000404 147.0
HFD2_k127_954188_9 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000000000000007071 142.0
HFD2_k127_96064_0 Peptidase family M1 domain K08776 - - 1.31e-208 678.0
HFD2_k127_96064_1 AMP-binding enzyme K00666 - - 2.918e-206 658.0
HFD2_k127_96064_10 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 297.0
HFD2_k127_96064_11 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001647 290.0
HFD2_k127_96064_12 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005469 268.0
HFD2_k127_96064_13 PaaX-like protein K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
HFD2_k127_96064_14 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 256.0
HFD2_k127_96064_15 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000004821 198.0
HFD2_k127_96064_16 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000002816 167.0
HFD2_k127_96064_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000007149 127.0
HFD2_k127_96064_18 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000003875 109.0
HFD2_k127_96064_19 Putative adhesin - - - 0.0000000000000001739 89.0
HFD2_k127_96064_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 1.987e-202 649.0
HFD2_k127_96064_20 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000009471 64.0
HFD2_k127_96064_3 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 602.0
HFD2_k127_96064_4 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 568.0
HFD2_k127_96064_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 484.0
HFD2_k127_96064_6 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 414.0
HFD2_k127_96064_7 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 389.0
HFD2_k127_96064_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 306.0
HFD2_k127_96064_9 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 301.0
HFD2_k127_989317_0 import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 439.0
HFD2_k127_989317_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 358.0
HFD2_k127_989317_10 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000005678 204.0
HFD2_k127_989317_11 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000007755 166.0
HFD2_k127_989317_12 SnoaL-like domain - - - 0.000000001039 66.0
HFD2_k127_989317_13 - - - - 0.0001564 51.0
HFD2_k127_989317_2 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 321.0
HFD2_k127_989317_3 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 316.0
HFD2_k127_989317_4 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005279 291.0
HFD2_k127_989317_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000003353 258.0
HFD2_k127_989317_6 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005494 263.0
HFD2_k127_989317_7 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005731 256.0
HFD2_k127_989317_8 import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
HFD2_k127_989317_9 FCD - - - 0.0000000000000000000000000000000000000000000000000000000007022 213.0