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Overview

ID MAG01670
Name HFD2_bin.7
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Piscinibacter
Species
Assembly information
Completeness (%) 69.37
Contamination (%) 0.79
GC content (%) 71.0
N50 (bp) 9,939
Genome size (bp) 3,899,816

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3871

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1016663_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 527.0
HFD2_k127_1016663_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 473.0
HFD2_k127_1016663_2 Rieske 2Fe-2S K19982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 419.0
HFD2_k127_1016663_3 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 419.0
HFD2_k127_1016663_4 Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 322.0
HFD2_k127_1016663_5 basic membrane K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 315.0
HFD2_k127_1016663_6 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000006511 175.0
HFD2_k127_1040061_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 561.0
HFD2_k127_1040061_1 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 481.0
HFD2_k127_1040061_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005742 306.0
HFD2_k127_1040061_3 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000363 242.0
HFD2_k127_1040061_4 PFAM O-methyltransferase - - - 0.000000000000000000000000000000000006977 153.0
HFD2_k127_1040061_5 Tetratricopeptide repeats - - - 0.00000000000000000000000000003524 134.0
HFD2_k127_1040061_6 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000002014 101.0
HFD2_k127_1040061_7 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000004242 69.0
HFD2_k127_1040061_8 Methyltransferase domain - - - 0.00006929 55.0
HFD2_k127_1040061_9 Bacterial transcriptional activator domain - - - 0.0008146 52.0
HFD2_k127_1043378_0 nitric oxide reductase K04561 - 1.7.2.5 0.0 1291.0
HFD2_k127_1043378_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 585.0
HFD2_k127_1043378_2 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 344.0
HFD2_k127_1043378_3 Transcriptional regulator K13771 - - 0.000000000000000000000000000000000000000000000000000004056 194.0
HFD2_k127_1043378_4 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000108 147.0
HFD2_k127_1043378_5 Mandelate Racemase Muconate Lactonizing K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.0000000000000000000005236 103.0
HFD2_k127_1051286_0 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 3.003e-238 748.0
HFD2_k127_1051286_1 PFAM Xanthine uracil vitamin C permease K02824 - - 7.485e-219 687.0
HFD2_k127_1051286_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 347.0
HFD2_k127_1051286_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 296.0
HFD2_k127_1051286_4 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000001737 184.0
HFD2_k127_1076110_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 491.0
HFD2_k127_1076110_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 485.0
HFD2_k127_1076110_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 439.0
HFD2_k127_1076110_3 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 351.0
HFD2_k127_1076110_4 transcriptional regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 301.0
HFD2_k127_1076110_5 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001964 284.0
HFD2_k127_1076110_6 - - - - 0.00000000005044 71.0
HFD2_k127_1078856_0 TonB dependent receptor - - - 0.0 1089.0
HFD2_k127_1078856_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 6.221e-298 933.0
HFD2_k127_1078856_10 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.000000000000000000000000000000000000000000000000002075 184.0
HFD2_k127_1078856_11 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000002366 159.0
HFD2_k127_1078856_12 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000003542 154.0
HFD2_k127_1078856_13 - - - - 0.000000000001429 68.0
HFD2_k127_1078856_2 cytochrome P450 - - - 7.707e-221 689.0
HFD2_k127_1078856_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 482.0
HFD2_k127_1078856_4 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 373.0
HFD2_k127_1078856_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 367.0
HFD2_k127_1078856_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K18954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
HFD2_k127_1078856_7 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 322.0
HFD2_k127_1078856_8 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000000000008991 218.0
HFD2_k127_1078856_9 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000000000000000001924 203.0
HFD2_k127_1095947_0 PFAM AAA ATPase central domain protein K07478 - - 6.453e-211 665.0
HFD2_k127_1095947_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 548.0
HFD2_k127_1095947_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 517.0
HFD2_k127_1095947_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
HFD2_k127_1095947_5 ABC transporter K01995 - - 0.000000000000000007644 83.0
HFD2_k127_1147788_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.615e-305 961.0
HFD2_k127_1147788_1 Zn_pept - - - 2.914e-292 920.0
HFD2_k127_1147788_2 Glutamine amido-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 404.0
HFD2_k127_1147788_3 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 402.0
HFD2_k127_1147788_4 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 359.0
HFD2_k127_1147788_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 284.0
HFD2_k127_1147788_6 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000326 232.0
HFD2_k127_1147788_7 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000004078 198.0
HFD2_k127_1147788_8 Tryptophan halogenase K21401 - 1.3.99.38 0.00000000000000000000000000000000000004909 144.0
HFD2_k127_1175051_0 Domain of unknown function (DUF4982) - - - 0.0 1186.0
HFD2_k127_1175051_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 1.669e-259 811.0
HFD2_k127_1175051_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 3.848e-200 658.0
HFD2_k127_1175051_3 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000002864 220.0
HFD2_k127_1203438_0 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 602.0
HFD2_k127_1203438_1 D-alanine--D-alanine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 574.0
HFD2_k127_1203438_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 367.0
HFD2_k127_1203438_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 317.0
HFD2_k127_1203438_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 291.0
HFD2_k127_1203438_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000001187 225.0
HFD2_k127_1203438_6 YHS domain - - - 0.0000000000000000000000000000000000000000000000000000009966 201.0
HFD2_k127_1203438_7 - - - - 0.00000000000000000000000000000000000000000000000001487 192.0
HFD2_k127_1264938_0 PFAM extracellular solute-binding protein family 1 K02027 - - 5.597e-263 815.0
HFD2_k127_1264938_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 588.0
HFD2_k127_1264938_2 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 479.0
HFD2_k127_1264938_3 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 447.0
HFD2_k127_1265629_0 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 589.0
HFD2_k127_1265629_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 586.0
HFD2_k127_1265629_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 368.0
HFD2_k127_1265629_3 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 330.0
HFD2_k127_1265629_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000001339 229.0
HFD2_k127_1316787_0 FAD dependent oxidoreductase - - - 0.0 1031.0
HFD2_k127_1316787_1 Fungalysin metallopeptidase (M36) K01417 - - 3.123e-214 691.0
HFD2_k127_1316787_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 399.0
HFD2_k127_1316787_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 317.0
HFD2_k127_1316787_4 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000006408 196.0
HFD2_k127_1316787_5 EamA-like transporter family - - - 0.00000000000000000000001246 101.0
HFD2_k127_1319860_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.735e-210 660.0
HFD2_k127_1319860_1 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 509.0
HFD2_k127_1319860_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 388.0
HFD2_k127_1319860_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008889 267.0
HFD2_k127_1319860_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 257.0
HFD2_k127_1319860_5 Predicted membrane protein (DUF2214) K08983 - - 0.00000000000000000000000000000000000000001118 158.0
HFD2_k127_1319860_6 Cytochrome c K08738 - - 0.0000003583 51.0
HFD2_k127_1325355_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 586.0
HFD2_k127_1325355_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 485.0
HFD2_k127_1325355_2 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 321.0
HFD2_k127_1325355_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001072 247.0
HFD2_k127_1325355_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000008097 198.0
HFD2_k127_1325355_5 type IV pilus modification protein PilV - - - 0.000000000000000000000000000000000000651 149.0
HFD2_k127_1332623_0 GAF domain K21405 - - 1.143e-256 808.0
HFD2_k127_1332623_1 Ammonium Transporter K03320,K06580 - - 1.155e-207 649.0
HFD2_k127_1332623_2 Belongs to the aldehyde dehydrogenase family K00138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 487.0
HFD2_k127_1337098_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 365.0
HFD2_k127_1337098_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 249.0
HFD2_k127_1337098_2 Cas6 Crispr - - - 0.0000000000000000000000000000000000000000000000000000000000001347 218.0
HFD2_k127_1337098_3 - - - - 0.000000000000000000000000000000000000000000000000000000003369 209.0
HFD2_k127_1337098_4 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000008691 196.0
HFD2_k127_1337098_5 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000622 172.0
HFD2_k127_1337098_6 - - - - 0.000000000000000001357 87.0
HFD2_k127_1402730_0 Activator of aromatic catabolism - - - 3.236e-232 736.0
HFD2_k127_1402730_1 Aldehyde dehydrogenase family K00141 - 1.2.1.28 1.492e-209 672.0
HFD2_k127_1402730_2 3-alpha-hydroxysteroid dehydrogenase carbonyl reductase oxidoreductase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 408.0
HFD2_k127_1402730_3 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 426.0
HFD2_k127_1402730_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 343.0
HFD2_k127_1402730_5 Protein of unknown function (DUF1302) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
HFD2_k127_1411004_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 414.0
HFD2_k127_1411004_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 338.0
HFD2_k127_1411004_2 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000003538 228.0
HFD2_k127_1411004_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000009748 235.0
HFD2_k127_1411004_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000005334 135.0
HFD2_k127_1437578_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 3.52e-233 727.0
HFD2_k127_1437578_1 Belongs to the CarA family K01956 - 6.3.5.5 1.451e-201 634.0
HFD2_k127_1437578_2 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 392.0
HFD2_k127_1437578_3 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 338.0
HFD2_k127_1437578_4 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 325.0
HFD2_k127_1437578_5 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
HFD2_k127_1439642_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 5.593e-254 791.0
HFD2_k127_1439642_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 532.0
HFD2_k127_1439642_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 452.0
HFD2_k127_1439642_3 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003349 270.0
HFD2_k127_1439642_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
HFD2_k127_1439642_5 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000000002082 158.0
HFD2_k127_1439642_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000001169 131.0
HFD2_k127_1474625_0 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 524.0
HFD2_k127_1474625_1 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 364.0
HFD2_k127_1474625_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007274 261.0
HFD2_k127_1474625_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000009754 221.0
HFD2_k127_1485900_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 8.263e-304 936.0
HFD2_k127_1485900_1 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 575.0
HFD2_k127_1485900_2 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 407.0
HFD2_k127_1485900_3 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
HFD2_k127_1485900_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000843 240.0
HFD2_k127_1485900_5 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000003092 168.0
HFD2_k127_1485900_6 - - - - 0.00000000000000000000000000000000000000000004319 180.0
HFD2_k127_1503133_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.993e-259 814.0
HFD2_k127_1503133_1 two-component sensor kinase K07649 - 2.7.13.3 6.502e-213 673.0
HFD2_k127_1503133_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 621.0
HFD2_k127_1503133_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 436.0
HFD2_k127_1503133_4 PFAM response regulator receiver K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 410.0
HFD2_k127_1503133_5 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000000000002912 279.0
HFD2_k127_1509197_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1576.0
HFD2_k127_1509197_1 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 582.0
HFD2_k127_1509197_10 Chromate resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 296.0
HFD2_k127_1509197_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002436 300.0
HFD2_k127_1509197_12 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000254 280.0
HFD2_k127_1509197_13 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 270.0
HFD2_k127_1509197_14 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
HFD2_k127_1509197_15 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000006416 221.0
HFD2_k127_1509197_16 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000000396 186.0
HFD2_k127_1509197_17 - - - - 0.000000000000000000000000000000000000000001739 159.0
HFD2_k127_1509197_18 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000559 159.0
HFD2_k127_1509197_19 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000002465 107.0
HFD2_k127_1509197_2 Histidine kinase K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 562.0
HFD2_k127_1509197_20 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000006496 104.0
HFD2_k127_1509197_21 - - - - 0.0000000000000000001556 93.0
HFD2_k127_1509197_22 - - - - 0.0000000000000002926 93.0
HFD2_k127_1509197_3 signal transduction histidine kinase K07678 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 569.0
HFD2_k127_1509197_4 Benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
HFD2_k127_1509197_5 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 524.0
HFD2_k127_1509197_6 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 481.0
HFD2_k127_1509197_7 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 429.0
HFD2_k127_1509197_8 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 413.0
HFD2_k127_1509197_9 PFAM response regulator receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
HFD2_k127_1523796_0 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1244.0
HFD2_k127_1523796_1 FAD binding domain K05712 - 1.14.13.127 3.31e-278 875.0
HFD2_k127_1523796_10 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
HFD2_k127_1523796_11 ECF sigma factor - - - 0.0000000000000000000000000000000000000001312 165.0
HFD2_k127_1523796_12 Protein of unknown function (DUF3455) - - - 0.00000000000000000000000000000000003591 151.0
HFD2_k127_1523796_13 Protein of unknown function (DUF2783) - - - 0.00000000000000000000001649 117.0
HFD2_k127_1523796_14 dksA traR - - - 0.00000000000001537 78.0
HFD2_k127_1523796_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01555 - 3.7.1.2 2.901e-194 625.0
HFD2_k127_1523796_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 424.0
HFD2_k127_1523796_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 408.0
HFD2_k127_1523796_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 354.0
HFD2_k127_1523796_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 306.0
HFD2_k127_1523796_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003332 292.0
HFD2_k127_1523796_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000074 251.0
HFD2_k127_1523796_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000426 253.0
HFD2_k127_1530288_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1714.0
HFD2_k127_1530288_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 589.0
HFD2_k127_1530288_10 Rhodanese-like domain - - - 0.00000000000000000000000000002074 133.0
HFD2_k127_1530288_11 - - - - 0.0000003161 62.0
HFD2_k127_1530288_2 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 527.0
HFD2_k127_1530288_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 452.0
HFD2_k127_1530288_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 444.0
HFD2_k127_1530288_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 381.0
HFD2_k127_1530288_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 380.0
HFD2_k127_1530288_7 Methyltransferase type 11 K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
HFD2_k127_1530288_8 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 292.0
HFD2_k127_1530288_9 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000008698 201.0
HFD2_k127_1531224_0 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 505.0
HFD2_k127_1531224_1 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005892 284.0
HFD2_k127_1531224_2 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
HFD2_k127_1531224_3 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
HFD2_k127_1531224_4 Protein of unknown function (DUF2970) - - - 0.000000000000000000000001002 107.0
HFD2_k127_1538558_0 Fumarylacetoacetate (Faa) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 555.0
HFD2_k127_1538558_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 459.0
HFD2_k127_1538558_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000001525 197.0
HFD2_k127_1538558_3 Protein of unknown function (DUF3567) - - - 0.000000000000000000000000000002805 122.0
HFD2_k127_1544394_0 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 1.538e-196 637.0
HFD2_k127_1544394_1 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 486.0
HFD2_k127_1544394_10 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000004712 241.0
HFD2_k127_1544394_11 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000001131 237.0
HFD2_k127_1544394_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000367 216.0
HFD2_k127_1544394_13 - - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
HFD2_k127_1544394_14 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000007007 193.0
HFD2_k127_1544394_15 - - - - 0.000000000000000000000000000000000000000000000000003987 202.0
HFD2_k127_1544394_16 PspC domain - - - 0.0000000000000000000000000000000000000136 146.0
HFD2_k127_1544394_17 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000002696 128.0
HFD2_k127_1544394_18 - - - - 0.000000000000000001563 89.0
HFD2_k127_1544394_19 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000009082 74.0
HFD2_k127_1544394_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 501.0
HFD2_k127_1544394_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 434.0
HFD2_k127_1544394_4 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 433.0
HFD2_k127_1544394_5 helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 408.0
HFD2_k127_1544394_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 327.0
HFD2_k127_1544394_7 isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 293.0
HFD2_k127_1544394_8 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001375 252.0
HFD2_k127_1544394_9 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001521 251.0
HFD2_k127_1560558_0 DNA photolyase K01669 - 4.1.99.3 2.074e-235 736.0
HFD2_k127_1560558_1 ATP-binding region, ATPase domain protein K02487,K06596 - - 3.013e-217 681.0
HFD2_k127_1560558_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 586.0
HFD2_k127_1560558_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 403.0
HFD2_k127_1560558_4 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
HFD2_k127_1560558_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 318.0
HFD2_k127_1560558_6 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
HFD2_k127_1560558_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000004854 199.0
HFD2_k127_1574352_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.536e-275 883.0
HFD2_k127_1574352_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 2.892e-196 626.0
HFD2_k127_1574352_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 589.0
HFD2_k127_1574352_3 - - - - 0.00000000000000000000000000000000000000000000000004308 188.0
HFD2_k127_1626873_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 617.0
HFD2_k127_1626873_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 589.0
HFD2_k127_1626873_2 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 392.0
HFD2_k127_1626873_3 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 396.0
HFD2_k127_1626873_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 321.0
HFD2_k127_1626873_5 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 317.0
HFD2_k127_1626873_6 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000004067 123.0
HFD2_k127_1626873_7 - - - - 0.00000000000000005607 91.0
HFD2_k127_1630976_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 8.936e-262 824.0
HFD2_k127_1630976_1 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 602.0
HFD2_k127_1630976_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 352.0
HFD2_k127_1630976_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
HFD2_k127_1630976_4 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007873 276.0
HFD2_k127_1630976_5 Aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000003529 257.0
HFD2_k127_1630976_6 Class ii aldolase - - - 0.0000000000000000000000000000000000000000000000000000000002171 209.0
HFD2_k127_1630976_7 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000002221 146.0
HFD2_k127_1676487_0 Flagellar motor switch K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 429.0
HFD2_k127_1676487_1 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 375.0
HFD2_k127_1676487_2 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 352.0
HFD2_k127_1676487_3 PFAM Short-chain dehydrogenase reductase SDR K22185 - 1.1.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000002273 265.0
HFD2_k127_1676487_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000001228 241.0
HFD2_k127_1676487_5 Flagellar motor switch protein fliN K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
HFD2_k127_1676487_6 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000000000000000003854 145.0
HFD2_k127_1676487_7 Flagellar biosynthesis protein, FliO K02418 - - 0.0000000000000000000000000001441 117.0
HFD2_k127_1691091_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 555.0
HFD2_k127_1691091_1 DNA topoisomerase III K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 539.0
HFD2_k127_1691091_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 413.0
HFD2_k127_1691091_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 413.0
HFD2_k127_1691091_4 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000000000000000000000000004293 202.0
HFD2_k127_1691091_5 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000000169 195.0
HFD2_k127_1734998_0 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 453.0
HFD2_k127_1734998_1 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 354.0
HFD2_k127_1734998_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139,K18903 - - 0.00000000000000000000000000000000000000000000000000003117 208.0
HFD2_k127_1734998_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000002254 198.0
HFD2_k127_1734998_4 - - - - 0.00000000000000000006532 94.0
HFD2_k127_1744013_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 325.0
HFD2_k127_1744013_1 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001198 235.0
HFD2_k127_1744013_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002469 213.0
HFD2_k127_1744013_3 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000007022 193.0
HFD2_k127_1754623_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000000000000001478 220.0
HFD2_k127_1754623_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000004679 204.0
HFD2_k127_1754623_2 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000009791 151.0
HFD2_k127_1754623_3 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000000000114 147.0
HFD2_k127_1754623_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000182 147.0
HFD2_k127_1754623_5 DUF167 K09131 - - 0.000000000000000000001624 106.0
HFD2_k127_1754623_6 - - - - 0.000000000000000000002336 97.0
HFD2_k127_1754623_7 Protein of unknown function (DUF2845) - - - 0.000000000000006731 79.0
HFD2_k127_1762484_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.706e-261 811.0
HFD2_k127_1762484_1 Cupin domain K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 560.0
HFD2_k127_1762484_10 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000008245 230.0
HFD2_k127_1762484_11 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000001675 228.0
HFD2_k127_1762484_12 Tautomerase enzyme - - - 0.000000000000000000000000000000001691 133.0
HFD2_k127_1762484_13 Domain of unknown function (DUF4865) - - - 0.000000000000000000000001835 110.0
HFD2_k127_1762484_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 449.0
HFD2_k127_1762484_3 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 402.0
HFD2_k127_1762484_4 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 374.0
HFD2_k127_1762484_5 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 361.0
HFD2_k127_1762484_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 332.0
HFD2_k127_1762484_7 Short-chain alcohol dehydrogenase K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 323.0
HFD2_k127_1762484_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000002746 263.0
HFD2_k127_1762484_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000112 237.0
HFD2_k127_1769337_0 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 554.0
HFD2_k127_1769337_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 386.0
HFD2_k127_1769337_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 324.0
HFD2_k127_1769337_3 Globin - - - 0.00000000000000000000000000000000000000003346 159.0
HFD2_k127_1769337_4 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000001285 131.0
HFD2_k127_1769337_5 Glycosyl hydrolases family 18 - - - 0.000000000000000000002545 107.0
HFD2_k127_1806251_0 FAD linked oxidases, C-terminal domain - - - 4.579e-213 685.0
HFD2_k127_1806251_1 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 591.0
HFD2_k127_1806251_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 369.0
HFD2_k127_1806251_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 302.0
HFD2_k127_1806251_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 296.0
HFD2_k127_1806251_5 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005541 276.0
HFD2_k127_1806251_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000001033 194.0
HFD2_k127_1806251_7 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000000000008429 192.0
HFD2_k127_1806251_8 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000000000001049 139.0
HFD2_k127_181414_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1480.0
HFD2_k127_181414_1 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 523.0
HFD2_k127_181414_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 389.0
HFD2_k127_181414_3 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003471 266.0
HFD2_k127_181414_4 diguanylate cyclase K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000604 291.0
HFD2_k127_181414_5 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD2_k127_181414_6 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000002 187.0
HFD2_k127_181414_7 LysE type translocator - - - 0.000000000000000000000000004748 119.0
HFD2_k127_1826228_0 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 2.315e-252 792.0
HFD2_k127_1826228_1 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 602.0
HFD2_k127_1826228_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K03776,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 419.0
HFD2_k127_1826228_3 Formaldehyde-activating enzyme (Fae) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 330.0
HFD2_k127_1826228_4 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 326.0
HFD2_k127_1826228_5 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 325.0
HFD2_k127_1826228_6 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 290.0
HFD2_k127_1826228_7 Belongs to the peptidase M48B family - - - 0.0000000000000000000000000000000000000000000000000000000000002333 218.0
HFD2_k127_1826855_0 metal-dependent hydrolase with the TIM-barrel fold - - - 1.051e-203 655.0
HFD2_k127_1826855_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 573.0
HFD2_k127_1826855_2 Transcriptional regulator, LysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 414.0
HFD2_k127_1826855_3 COG1072 Panthothenate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
HFD2_k127_1826855_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001855 256.0
HFD2_k127_1826855_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009695 256.0
HFD2_k127_1826855_6 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
HFD2_k127_1826855_7 response to heat K03668,K09914 - - 0.0000000000000000000000000000000005027 139.0
HFD2_k127_1827290_0 flagellar hook-associated protein K02396 - - 6.449e-219 698.0
HFD2_k127_1827290_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 561.0
HFD2_k127_1827290_2 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 545.0
HFD2_k127_1827290_3 Belongs to the bacterial flagellin family K02397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 409.0
HFD2_k127_1827290_4 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 330.0
HFD2_k127_1827290_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000002154 88.0
HFD2_k127_1843686_0 Major facilitator Superfamily K08162,K08226,K16211 - - 8.594e-259 807.0
HFD2_k127_1843686_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 456.0
HFD2_k127_1843686_2 Fumarylacetoacetate (FAA) hydrolase family K02509,K18364 - 4.2.1.132,4.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 444.0
HFD2_k127_1843686_3 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 415.0
HFD2_k127_1843686_4 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 389.0
HFD2_k127_1843686_5 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 294.0
HFD2_k127_1843686_6 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
HFD2_k127_1843686_7 PFAM 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000008449 204.0
HFD2_k127_1843686_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000007059 150.0
HFD2_k127_1843686_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.00000008217 66.0
HFD2_k127_1853950_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 452.0
HFD2_k127_1853950_1 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 385.0
HFD2_k127_1853950_2 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 359.0
HFD2_k127_1853950_3 PFAM aminotransferase, class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 340.0
HFD2_k127_1853950_4 PFAM lipopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001702 269.0
HFD2_k127_1853950_5 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000002173 214.0
HFD2_k127_1853951_0 Polysaccharide biosynthesis/export protein - - - 2.44e-213 692.0
HFD2_k127_1853951_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 351.0
HFD2_k127_1853951_2 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 316.0
HFD2_k127_1853951_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000049 258.0
HFD2_k127_1853951_4 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000000000000006515 186.0
HFD2_k127_1870964_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.384e-266 851.0
HFD2_k127_1870964_1 Receptor family ligand binding region K01999 - - 6.135e-201 630.0
HFD2_k127_1870964_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 462.0
HFD2_k127_1870964_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 369.0
HFD2_k127_1870964_4 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 312.0
HFD2_k127_1870964_5 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000001236 119.0
HFD2_k127_1897635_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 571.0
HFD2_k127_1897635_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 535.0
HFD2_k127_1897635_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000002679 117.0
HFD2_k127_1897635_2 Amino-transferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 482.0
HFD2_k127_1897635_3 PFAM VanZ family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 415.0
HFD2_k127_1897635_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
HFD2_k127_1897635_5 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
HFD2_k127_1897635_6 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000001592 234.0
HFD2_k127_1897635_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000001122 194.0
HFD2_k127_1897635_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000009515 189.0
HFD2_k127_1897635_9 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000000000000002449 151.0
HFD2_k127_1907241_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.115e-223 694.0
HFD2_k127_1907241_1 PFAM helix-turn-helix protein RpiR K19337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 483.0
HFD2_k127_1907241_2 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 331.0
HFD2_k127_1907241_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000187 174.0
HFD2_k127_1907241_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000007625 150.0
HFD2_k127_1907241_5 COG1985 Pyrimidine reductase, riboflavin biosynthesis K14654 - 1.1.1.302 0.000000000000000004445 96.0
HFD2_k127_1907241_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000007848 70.0
HFD2_k127_1921819_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1010.0
HFD2_k127_1921819_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 1.051e-212 671.0
HFD2_k127_1921819_10 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000003313 213.0
HFD2_k127_1921819_11 PFAM Blue (type 1) copper domain - - - 0.0000000000000000000000000000000000000000000004224 173.0
HFD2_k127_1921819_12 - - - - 0.000000000000000000000000000000001345 134.0
HFD2_k127_1921819_13 Copper binding periplasmic protein CusF - - - 0.00000000000000000000003824 108.0
HFD2_k127_1921819_2 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 532.0
HFD2_k127_1921819_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 450.0
HFD2_k127_1921819_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 397.0
HFD2_k127_1921819_5 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 347.0
HFD2_k127_1921819_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 322.0
HFD2_k127_1921819_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 314.0
HFD2_k127_1921819_8 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 303.0
HFD2_k127_1921819_9 HAD-hyrolase-like K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 290.0
HFD2_k127_1928115_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1080.0
HFD2_k127_1928115_1 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 503.0
HFD2_k127_1928115_2 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 435.0
HFD2_k127_1928115_3 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 351.0
HFD2_k127_1928115_4 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000201 179.0
HFD2_k127_1928115_5 Acetyltransferase (GNAT) domain K02348 - - 0.0000000000000000000000000000000000000000000004217 171.0
HFD2_k127_1928115_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000002457 129.0
HFD2_k127_1964079_0 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 586.0
HFD2_k127_1964079_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 561.0
HFD2_k127_1964079_2 PFAM AMP-dependent synthetase and ligase K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 556.0
HFD2_k127_1964079_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 503.0
HFD2_k127_1964079_4 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000243 214.0
HFD2_k127_1968691_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 525.0
HFD2_k127_1968691_1 basic membrane K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 346.0
HFD2_k127_1968691_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004835 254.0
HFD2_k127_1990291_0 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 0.0 1393.0
HFD2_k127_1990291_1 Type VI secretion system, TssF K11896 - - 8.728e-199 638.0
HFD2_k127_1990291_2 PFAM virulence protein, SciE type K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
HFD2_k127_1990291_3 FHA domain K07169,K11913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 360.0
HFD2_k127_1990291_4 Rhs Element Vgr Protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 349.0
HFD2_k127_1990291_5 type VI secretion protein K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 323.0
HFD2_k127_1990291_6 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.000000000000000000000000000000000000333 154.0
HFD2_k127_1990291_7 Double zinc ribbon - - - 0.00000000000000000000000004819 115.0
HFD2_k127_1990291_8 Domain of unknown function (DUF4123) - - - 0.000000003085 71.0
HFD2_k127_2007493_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1274.0
HFD2_k127_2007493_1 DNA polymerase X family K02347 - - 5.267e-228 722.0
HFD2_k127_2007493_10 GYD domain - - - 0.000000000000000000000000000009784 122.0
HFD2_k127_2007493_11 daunorubicin resistance ABC transporter membrane protein K01992 - - 0.0000000000000000000000008835 106.0
HFD2_k127_2007493_12 Glycine-zipper domain - - - 0.00000000000000000000002101 109.0
HFD2_k127_2007493_2 PFAM 20S proteasome, A and B subunits K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 481.0
HFD2_k127_2007493_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 444.0
HFD2_k127_2007493_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 370.0
HFD2_k127_2007493_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002073 250.0
HFD2_k127_2007493_6 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001426 243.0
HFD2_k127_2007493_7 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003261 217.0
HFD2_k127_2007493_8 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000009971 182.0
HFD2_k127_2007493_9 - - - - 0.00000000000000000000000000000000000000000000002472 175.0
HFD2_k127_2013400_0 Cytochrome C biogenesis protein transmembrane region K04084,K08344 - 1.8.1.8 1.586e-260 835.0
HFD2_k127_2013400_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 509.0
HFD2_k127_2013400_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002056 254.0
HFD2_k127_2013400_3 SMP-30 Gluconolaconase K13874,K14274 - 3.1.1.15 0.00000000000000000000000000000000000000000000000000000000006061 205.0
HFD2_k127_2013400_4 ATP synthase I chain K02116 - - 0.00000000000000000000000000000000000000000000000135 181.0
HFD2_k127_2013400_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000001429 152.0
HFD2_k127_2013400_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000004698 68.0
HFD2_k127_2034351_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 593.0
HFD2_k127_2034351_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 425.0
HFD2_k127_2034351_10 - - - - 0.00000000000000000008284 102.0
HFD2_k127_2034351_11 IMP dehydrogenase activity - - - 0.00000000000000003194 96.0
HFD2_k127_2034351_12 - - - - 0.00000000000000004616 83.0
HFD2_k127_2034351_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000009558 87.0
HFD2_k127_2034351_2 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 402.0
HFD2_k127_2034351_3 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 366.0
HFD2_k127_2034351_4 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 375.0
HFD2_k127_2034351_5 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 336.0
HFD2_k127_2034351_6 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 305.0
HFD2_k127_2034351_7 PFAM glycosyl transferase family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000002359 250.0
HFD2_k127_2034351_8 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000001647 227.0
HFD2_k127_2034351_9 Cytochrome c - - - 0.000000000000000000000003741 114.0
HFD2_k127_2037231_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.84e-294 924.0
HFD2_k127_2037231_1 Dehydratase family K01687 - 4.2.1.9 2.981e-286 887.0
HFD2_k127_2037231_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 441.0
HFD2_k127_2037231_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002257 282.0
HFD2_k127_2037231_4 phosphohistidine phosphatase, SixA - - - 0.00000000000000000000000000000000000000000000000000000001136 213.0
HFD2_k127_2037231_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000004098 179.0
HFD2_k127_2037231_6 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000007124 172.0
HFD2_k127_2037231_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000002118 62.0
HFD2_k127_2041839_0 Reductase C-terminal K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 510.0
HFD2_k127_2041839_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 371.0
HFD2_k127_2041839_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 363.0
HFD2_k127_2041839_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 350.0
HFD2_k127_2041839_4 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 340.0
HFD2_k127_2041839_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 329.0
HFD2_k127_2041839_6 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000002807 264.0
HFD2_k127_2041839_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
HFD2_k127_2041839_8 Cold shock protein K03704 - - 0.0000000000000000000000000000000799 127.0
HFD2_k127_2041839_9 - - - - 0.00000000000001308 78.0
HFD2_k127_2042613_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 514.0
HFD2_k127_2042613_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 479.0
HFD2_k127_2042613_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
HFD2_k127_2042613_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 374.0
HFD2_k127_2042613_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 308.0
HFD2_k127_2042613_5 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000000000000002308 181.0
HFD2_k127_2042613_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000009179 160.0
HFD2_k127_2044311_0 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 332.0
HFD2_k127_2044311_1 Protein of unknown function (DUF2726) - - - 0.0000000000000000000000000000000000000000000000000002942 193.0
HFD2_k127_2044311_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000075 188.0
HFD2_k127_2044311_3 PFAM T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000004603 124.0
HFD2_k127_2044311_4 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000002106 104.0
HFD2_k127_2044311_5 Flagella basal body rod protein - - - 0.00000000000000000002575 94.0
HFD2_k127_2044311_6 - - - - 0.00000000027 70.0
HFD2_k127_2047177_0 Required for chromosome condensation and partitioning K03529 - - 6.045e-249 781.0
HFD2_k127_2047177_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002303 273.0
HFD2_k127_2047177_2 CpXC protein - - - 0.0000000000000000000000000000000000000000000000000002609 192.0
HFD2_k127_2047177_3 LysM domain - - - 0.0000000000000000000000000000000000000000000000006989 201.0
HFD2_k127_2060418_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 1.414e-242 760.0
HFD2_k127_2060418_1 ABC transporter K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 593.0
HFD2_k127_2060418_2 Gluconolactonase K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 586.0
HFD2_k127_2060418_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 463.0
HFD2_k127_2060418_4 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 436.0
HFD2_k127_2060418_5 Belongs to the IlvD Edd family K01687,K13875,K22186 - 4.2.1.25,4.2.1.82,4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001056 275.0
HFD2_k127_2082020_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 492.0
HFD2_k127_2082020_1 transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005493 267.0
HFD2_k127_2082020_2 - - - - 0.00000000000000000000000000000000000000000003879 178.0
HFD2_k127_2082020_3 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.000000000000003561 76.0
HFD2_k127_2117962_0 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 482.0
HFD2_k127_2117962_1 LysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 401.0
HFD2_k127_2117962_2 OmpW family K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 285.0
HFD2_k127_2117962_3 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008372 276.0
HFD2_k127_2117962_4 TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000000000000008378 151.0
HFD2_k127_2117962_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000173 104.0
HFD2_k127_2117962_6 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000006816 78.0
HFD2_k127_2131616_0 AMP-binding enzyme K01895 - 6.2.1.1 2.795e-293 919.0
HFD2_k127_2131616_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.366e-259 809.0
HFD2_k127_2131616_10 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003654 256.0
HFD2_k127_2131616_11 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000002215 262.0
HFD2_k127_2131616_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001182 241.0
HFD2_k127_2131616_13 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000003038 220.0
HFD2_k127_2131616_14 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000008876 215.0
HFD2_k127_2131616_15 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000003458 198.0
HFD2_k127_2131616_16 - - - - 0.0000000101 67.0
HFD2_k127_2131616_2 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 566.0
HFD2_k127_2131616_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 529.0
HFD2_k127_2131616_4 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
HFD2_k127_2131616_5 Protein tyrosine kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 386.0
HFD2_k127_2131616_6 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 359.0
HFD2_k127_2131616_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 370.0
HFD2_k127_2131616_8 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005377 273.0
HFD2_k127_2131616_9 Protein of unknown function (DUF3717) K06938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003292 254.0
HFD2_k127_216625_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.288e-209 654.0
HFD2_k127_216625_1 ABC transporter - - - 1.102e-203 653.0
HFD2_k127_216625_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001771 311.0
HFD2_k127_216625_3 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009764 292.0
HFD2_k127_2172841_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.001e-245 765.0
HFD2_k127_2172841_1 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K10441,K10548 - 3.6.3.17 1.648e-244 763.0
HFD2_k127_2172841_2 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 590.0
HFD2_k127_2172841_3 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 527.0
HFD2_k127_2172841_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000002722 238.0
HFD2_k127_2172841_5 Periplasmic binding protein domain K10543,K10546 - - 0.00000000000000000000000000000000000000000000000000000006683 196.0
HFD2_k127_2177916_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.61e-309 955.0
HFD2_k127_2177916_1 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 284.0
HFD2_k127_2177916_2 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 286.0
HFD2_k127_2177916_3 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000000000000005166 154.0
HFD2_k127_2198877_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1364.0
HFD2_k127_2198877_1 PFAM Glycosyl transferase, family K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 415.0
HFD2_k127_2198877_2 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 349.0
HFD2_k127_2198877_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 332.0
HFD2_k127_2198877_4 TIGRFAM nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000001129 229.0
HFD2_k127_2198877_5 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K00362,K05297 - 1.18.1.1,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000001308 218.0
HFD2_k127_2198877_6 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000001499 135.0
HFD2_k127_2200267_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1060.0
HFD2_k127_2200267_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 3.27e-288 889.0
HFD2_k127_2200267_2 Dynamin family - - - 2.86e-254 802.0
HFD2_k127_2200267_3 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 508.0
HFD2_k127_2200267_4 DeoR C terminal sensor domain K02081 - - 0.0000000000000000000000000000000000000000000000359 172.0
HFD2_k127_2203010_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1355.0
HFD2_k127_2203010_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1198.0
HFD2_k127_2203010_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 400.0
HFD2_k127_2203010_11 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 378.0
HFD2_k127_2203010_12 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 348.0
HFD2_k127_2203010_13 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 332.0
HFD2_k127_2203010_14 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 342.0
HFD2_k127_2203010_15 rRNA methyltransferase K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
HFD2_k127_2203010_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
HFD2_k127_2203010_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000197 246.0
HFD2_k127_2203010_18 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000001323 231.0
HFD2_k127_2203010_19 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000004269 243.0
HFD2_k127_2203010_2 type II secretion system protein E K02283 - - 2.392e-200 633.0
HFD2_k127_2203010_20 TadE-like protein - - - 0.0000000000000000000000000000000000000000000004088 179.0
HFD2_k127_2203010_21 TadE-like protein - - - 0.000000000000000000000000000000105 141.0
HFD2_k127_2203010_22 cytochrome c biogenesis K02200 - - 0.000006525 59.0
HFD2_k127_2203010_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 612.0
HFD2_k127_2203010_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 574.0
HFD2_k127_2203010_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 559.0
HFD2_k127_2203010_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 458.0
HFD2_k127_2203010_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 458.0
HFD2_k127_2203010_8 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 436.0
HFD2_k127_2203010_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 422.0
HFD2_k127_2244449_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 466.0
HFD2_k127_2244449_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 295.0
HFD2_k127_2244449_2 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000001038 187.0
HFD2_k127_2244449_3 Pilin (bacterial filament) K02650 - - 0.00000000000000000000000000000000000000000002656 180.0
HFD2_k127_2244449_4 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.00000005365 56.0
HFD2_k127_2266118_0 ABC transporter, transmembrane region K06147 - - 9.507e-284 882.0
HFD2_k127_2266118_1 major facilitator superfamily K03446 - - 2.145e-262 816.0
HFD2_k127_2266118_2 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 578.0
HFD2_k127_2266118_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 559.0
HFD2_k127_2266118_4 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 561.0
HFD2_k127_2266118_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 522.0
HFD2_k127_2266118_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 458.0
HFD2_k127_2266118_7 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
HFD2_k127_2266118_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000002803 182.0
HFD2_k127_2281095_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 1.042e-242 774.0
HFD2_k127_2281095_1 HDOD domain K08282 - 2.7.11.1 0.000000000000000000000001805 106.0
HFD2_k127_2290954_0 Histidine kinase K07638 - 2.7.13.3 7.456e-217 679.0
HFD2_k127_2290954_1 PFAM response regulator receiver K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 462.0
HFD2_k127_2290954_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 287.0
HFD2_k127_2290954_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000001926 239.0
HFD2_k127_2293100_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1071.0
HFD2_k127_2293100_1 MerR, DNA binding K19591,K19592 - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
HFD2_k127_2293100_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000002041 81.0
HFD2_k127_2293100_3 Outer membrane efflux protein - - - 0.00000376 54.0
HFD2_k127_2300378_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.8e-322 990.0
HFD2_k127_2300378_1 PFAM AMP-dependent synthetase and ligase K00666 - - 1.591e-318 981.0
HFD2_k127_2300378_10 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 326.0
HFD2_k127_2300378_11 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002222 273.0
HFD2_k127_2300378_12 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002043 286.0
HFD2_k127_2300378_13 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000002076 239.0
HFD2_k127_2300378_14 Thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000003246 229.0
HFD2_k127_2300378_15 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000006508 186.0
HFD2_k127_2300378_16 Protein of unknown function, DUF481 K07283 - - 0.00000000000000000000000000000000000002122 155.0
HFD2_k127_2300378_17 GYD domain - - - 0.000000000000000000000000000000000019 139.0
HFD2_k127_2300378_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.9e-239 755.0
HFD2_k127_2300378_3 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 558.0
HFD2_k127_2300378_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 531.0
HFD2_k127_2300378_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 442.0
HFD2_k127_2300378_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 436.0
HFD2_k127_2300378_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 445.0
HFD2_k127_2300378_8 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 384.0
HFD2_k127_2300378_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
HFD2_k127_2316719_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 521.0
HFD2_k127_2316719_1 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 356.0
HFD2_k127_2316719_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002606 271.0
HFD2_k127_2316719_3 TonB C terminal K03646 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002515 250.0
HFD2_k127_2316719_4 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000001311 194.0
HFD2_k127_2316719_5 system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000000008997 170.0
HFD2_k127_2316719_6 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000005742 129.0
HFD2_k127_2366872_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1030.0
HFD2_k127_2366872_1 Rieske 2Fe-2S K00499 - 1.14.15.7 3.519e-194 610.0
HFD2_k127_2366872_2 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 455.0
HFD2_k127_2366872_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 423.0
HFD2_k127_2366872_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 435.0
HFD2_k127_2366872_5 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 381.0
HFD2_k127_2366872_6 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 374.0
HFD2_k127_2366872_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000001619 118.0
HFD2_k127_242234_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 550.0
HFD2_k127_242234_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 416.0
HFD2_k127_242234_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 314.0
HFD2_k127_242234_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 283.0
HFD2_k127_242234_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001006 177.0
HFD2_k127_242234_5 Heavy-metal resistance - - - 0.00000000000000000000000000000000007972 143.0
HFD2_k127_2431762_0 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 585.0
HFD2_k127_2431762_1 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 571.0
HFD2_k127_2431762_10 TOBE domain - - - 0.000000000000000000000000121 109.0
HFD2_k127_2431762_11 PFAM Thioredoxin K00384 - 1.8.1.9 0.0000000000000000000000001412 113.0
HFD2_k127_2431762_2 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 482.0
HFD2_k127_2431762_3 sulfate ABC transporter K02046,K15496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 441.0
HFD2_k127_2431762_4 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 419.0
HFD2_k127_2431762_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 399.0
HFD2_k127_2431762_6 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 383.0
HFD2_k127_2431762_7 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005396 271.0
HFD2_k127_2431762_8 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 265.0
HFD2_k127_2431762_9 Catalyzes the desulfonation of aliphatic sulfonates K04091 - 1.14.14.5 0.000000000000000000000000000000000000004536 146.0
HFD2_k127_2468967_0 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 321.0
HFD2_k127_2468967_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
HFD2_k127_2468967_2 Type ii and iii secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001019 246.0
HFD2_k127_2489244_0 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 1.016e-250 784.0
HFD2_k127_2489244_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.856e-228 711.0
HFD2_k127_2489244_10 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000001364 77.0
HFD2_k127_2489244_2 PFAM AMP-dependent synthetase and ligase - - - 9.276e-222 699.0
HFD2_k127_2489244_3 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 1.457e-205 640.0
HFD2_k127_2489244_4 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 484.0
HFD2_k127_2489244_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 458.0
HFD2_k127_2489244_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 340.0
HFD2_k127_2489244_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 333.0
HFD2_k127_2489244_8 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000001064 211.0
HFD2_k127_2489244_9 VanZ like family - - - 0.000000000000000001191 100.0
HFD2_k127_2494348_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 552.0
HFD2_k127_2494348_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 543.0
HFD2_k127_2494348_2 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 533.0
HFD2_k127_2494348_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 349.0
HFD2_k127_2494348_4 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
HFD2_k127_2494348_5 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002598 265.0
HFD2_k127_2494348_6 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000003373 201.0
HFD2_k127_2494348_7 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000000000008806 211.0
HFD2_k127_2494348_8 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000003962 183.0
HFD2_k127_2494348_9 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000008323 121.0
HFD2_k127_2510795_0 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 8.422e-289 890.0
HFD2_k127_2510795_1 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 546.0
HFD2_k127_2510795_10 Domain of unknown function (DUF4154) - - - 0.0000000000000000001019 98.0
HFD2_k127_2510795_11 - - - - 0.0000000000002266 83.0
HFD2_k127_2510795_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 523.0
HFD2_k127_2510795_3 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 501.0
HFD2_k127_2510795_4 receptor K02014,K16089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 389.0
HFD2_k127_2510795_5 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 359.0
HFD2_k127_2510795_6 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 321.0
HFD2_k127_2510795_7 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 327.0
HFD2_k127_2510795_8 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 293.0
HFD2_k127_2510795_9 DJ-1 PfpI family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001031 285.0
HFD2_k127_2568999_0 amino acid K01999 - - 3.616e-222 699.0
HFD2_k127_2568999_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.515e-210 660.0
HFD2_k127_2568999_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 506.0
HFD2_k127_2568999_3 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 425.0
HFD2_k127_2568999_4 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 392.0
HFD2_k127_2568999_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000001509 173.0
HFD2_k127_257994_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1373.0
HFD2_k127_257994_1 PFAM Sulfatase K03760 - 2.7.8.43 4.047e-208 666.0
HFD2_k127_257994_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 473.0
HFD2_k127_257994_3 PFAM ATP-binding region, ATPase domain protein K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 415.0
HFD2_k127_257994_4 Two component transcriptional regulator K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 307.0
HFD2_k127_257994_5 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007597 267.0
HFD2_k127_257994_6 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000000001977 158.0
HFD2_k127_257994_7 domain protein K03320 - - 0.00000000000000000000000000000000000000002624 169.0
HFD2_k127_2608695_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 5.709e-276 866.0
HFD2_k127_2608695_1 Parallel beta-helix repeats - - - 9.136e-275 861.0
HFD2_k127_2608695_2 Periplasmic binding protein domain K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 344.0
HFD2_k127_2608695_3 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000001032 120.0
HFD2_k127_2608695_4 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.00000000000000000000007977 108.0
HFD2_k127_2608695_5 PFAM transcriptional regulator domain protein - - - 0.00000000000001057 80.0
HFD2_k127_2632321_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.202e-308 966.0
HFD2_k127_2632321_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 3.233e-243 757.0
HFD2_k127_2632321_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.014e-222 727.0
HFD2_k127_2632321_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.548e-217 684.0
HFD2_k127_2639164_0 PFAM Alcohol dehydrogenase GroES domain protein K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 568.0
HFD2_k127_2639164_1 PFAM Periplasmic binding protein LacI transcriptional regulator K06145 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 538.0
HFD2_k127_2639164_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 444.0
HFD2_k127_2639164_3 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 402.0
HFD2_k127_2639164_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 409.0
HFD2_k127_2639164_5 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002277 259.0
HFD2_k127_2639164_6 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.0000000000004942 73.0
HFD2_k127_2651229_0 Amidohydrolase family K18456 - 3.5.4.32 2.195e-236 752.0
HFD2_k127_2651229_1 Permease family K03458 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 495.0
HFD2_k127_2651229_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000151 156.0
HFD2_k127_2651229_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000001904 124.0
HFD2_k127_2651229_12 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000002412 111.0
HFD2_k127_2651229_2 SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 427.0
HFD2_k127_2651229_3 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 394.0
HFD2_k127_2651229_4 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 374.0
HFD2_k127_2651229_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 335.0
HFD2_k127_2651229_6 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 264.0
HFD2_k127_2651229_7 - - - - 0.0000000000000000000000000000000000000000000000000000000666 209.0
HFD2_k127_2651229_8 transcriptional regulator, merr family - - - 0.0000000000000000000000000000000000000000000000001433 184.0
HFD2_k127_2651229_9 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000000000000001656 172.0
HFD2_k127_2656123_0 Guanine deaminase K01487 - 3.5.4.3 1.286e-209 660.0
HFD2_k127_2656123_1 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 436.0
HFD2_k127_2656123_2 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 357.0
HFD2_k127_265987_0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000000001539 193.0
HFD2_k127_265987_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000004009 170.0
HFD2_k127_265987_2 domain, Protein K19231 - - 0.00000000000000000000000000005215 136.0
HFD2_k127_265987_3 Caspase domain - - - 0.000000000000002441 92.0
HFD2_k127_2670054_0 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 1.842e-202 636.0
HFD2_k127_2670054_1 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 392.0
HFD2_k127_2670054_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 338.0
HFD2_k127_2670054_3 Hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000003289 217.0
HFD2_k127_2670054_4 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.000000000000000000000000000000000000000000000000000000915 198.0
HFD2_k127_2694999_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 428.0
HFD2_k127_2694999_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 384.0
HFD2_k127_2694999_10 Belongs to the UPF0434 family K09791 - - 0.0000000000000000004591 89.0
HFD2_k127_2694999_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 389.0
HFD2_k127_2694999_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 377.0
HFD2_k127_2694999_4 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 343.0
HFD2_k127_2694999_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 334.0
HFD2_k127_2694999_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
HFD2_k127_2694999_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
HFD2_k127_2694999_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000165 197.0
HFD2_k127_2694999_9 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000002005 119.0
HFD2_k127_271048_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 513.0
HFD2_k127_271048_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 347.0
HFD2_k127_271048_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
HFD2_k127_271048_3 Belongs to the UPF0225 family K09858 - - 0.00000000000000000000000000000000000000000003322 180.0
HFD2_k127_271048_4 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000009322 148.0
HFD2_k127_2718676_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 3.29e-262 836.0
HFD2_k127_2718676_1 AMP-binding enzyme K01897 - 6.2.1.3 4.913e-234 738.0
HFD2_k127_2718676_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 539.0
HFD2_k127_2718676_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 531.0
HFD2_k127_2718676_4 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 497.0
HFD2_k127_2718676_5 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 421.0
HFD2_k127_2718676_6 signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 345.0
HFD2_k127_2718676_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000004035 133.0
HFD2_k127_2721133_0 TonB dependent receptor K02014 - - 0.0 1119.0
HFD2_k127_2721133_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.946e-273 854.0
HFD2_k127_2721133_10 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000008269 231.0
HFD2_k127_2721133_11 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000000000000000000000000000000006712 228.0
HFD2_k127_2721133_12 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000001222 167.0
HFD2_k127_2721133_13 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000002171 147.0
HFD2_k127_2721133_2 Required for chromosome condensation and partitioning K03529 - - 1.125e-207 652.0
HFD2_k127_2721133_3 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 591.0
HFD2_k127_2721133_4 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 571.0
HFD2_k127_2721133_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 559.0
HFD2_k127_2721133_6 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 499.0
HFD2_k127_2721133_7 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 426.0
HFD2_k127_2721133_8 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 379.0
HFD2_k127_2721133_9 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 353.0
HFD2_k127_2724238_0 Putative diguanylate phosphodiesterase - - - 1.625e-295 935.0
HFD2_k127_2724238_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 3.101e-213 671.0
HFD2_k127_2724238_10 Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000000000002836 234.0
HFD2_k127_2724238_11 lipase activity - - - 0.000000000000000000000000000000000000000000000000000000000003959 221.0
HFD2_k127_2724238_12 - - - - 0.00000000000000000000000000000000000000000000000005169 189.0
HFD2_k127_2724238_13 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000659 183.0
HFD2_k127_2724238_14 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000001975 177.0
HFD2_k127_2724238_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000005967 164.0
HFD2_k127_2724238_17 - - - - 0.000000000000000000000000000005554 122.0
HFD2_k127_2724238_18 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000007386 84.0
HFD2_k127_2724238_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 532.0
HFD2_k127_2724238_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 536.0
HFD2_k127_2724238_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 497.0
HFD2_k127_2724238_5 PFAM Thioredoxin domain K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 429.0
HFD2_k127_2724238_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 409.0
HFD2_k127_2724238_7 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 332.0
HFD2_k127_2724238_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 336.0
HFD2_k127_2724238_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
HFD2_k127_2738439_0 Tetratricopeptide repeat - - - 0.0 1292.0
HFD2_k127_2738439_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 3.283e-254 790.0
HFD2_k127_2738439_10 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000008043 209.0
HFD2_k127_2738439_11 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000001638 213.0
HFD2_k127_2738439_12 - - - - 0.00000000000000000000000000000001078 139.0
HFD2_k127_2738439_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 607.0
HFD2_k127_2738439_3 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 499.0
HFD2_k127_2738439_4 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 451.0
HFD2_k127_2738439_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 430.0
HFD2_k127_2738439_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 394.0
HFD2_k127_2738439_7 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 359.0
HFD2_k127_2738439_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001647 273.0
HFD2_k127_2738439_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
HFD2_k127_2741024_0 alpha-2-macroglobulin domain protein K06894 - - 2.119e-231 748.0
HFD2_k127_2741024_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 517.0
HFD2_k127_2741024_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 263.0
HFD2_k127_2741024_3 Virulence factor membrane-bound polymerase, C-terminal - - - 0.0000000000000000000000000000000000000000001244 164.0
HFD2_k127_2745590_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 0.0 1290.0
HFD2_k127_2745590_1 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 517.0
HFD2_k127_2745590_2 TIGRFAM xanthine dehydrogenase accessory protein XdhC K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 329.0
HFD2_k127_2745590_3 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000001725 78.0
HFD2_k127_2749607_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.715e-248 789.0
HFD2_k127_2749607_1 Phospholipase D. Active site motifs. K00995,K06131 - 2.7.8.5 1.184e-206 651.0
HFD2_k127_2749607_10 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000001263 240.0
HFD2_k127_2749607_11 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000003303 230.0
HFD2_k127_2749607_12 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000006667 216.0
HFD2_k127_2749607_13 - - - - 0.00000000000000000000000000000000000000000000000000000000001 212.0
HFD2_k127_2749607_14 - - - - 0.0000000000000000000000000000000000000000000000000000000001717 234.0
HFD2_k127_2749607_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000005579 198.0
HFD2_k127_2749607_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000006592 153.0
HFD2_k127_2749607_17 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000001305 142.0
HFD2_k127_2749607_18 Glycine zipper 2TM domain - - - 0.0000000000000000000000002876 111.0
HFD2_k127_2749607_19 Protein of unknown function (DUF3309) - - - 0.00000000000000001283 87.0
HFD2_k127_2749607_2 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 595.0
HFD2_k127_2749607_21 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 0.000000000000735 78.0
HFD2_k127_2749607_22 - - - - 0.0000008531 61.0
HFD2_k127_2749607_3 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 514.0
HFD2_k127_2749607_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 517.0
HFD2_k127_2749607_5 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 484.0
HFD2_k127_2749607_6 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 397.0
HFD2_k127_2749607_7 Crp Fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 393.0
HFD2_k127_2749607_8 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 331.0
HFD2_k127_2749607_9 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001438 244.0
HFD2_k127_2764011_0 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 6.425e-278 863.0
HFD2_k127_2764011_1 D-isomer specific 2-hydroxyacid dehydrogenase K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 486.0
HFD2_k127_2764011_10 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HFD2_k127_2764011_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 455.0
HFD2_k127_2764011_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 419.0
HFD2_k127_2764011_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 391.0
HFD2_k127_2764011_5 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 397.0
HFD2_k127_2764011_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 370.0
HFD2_k127_2764011_7 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 357.0
HFD2_k127_2764011_8 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004498 266.0
HFD2_k127_2764011_9 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003766 259.0
HFD2_k127_279255_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1090.0
HFD2_k127_279255_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 536.0
HFD2_k127_279255_2 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 481.0
HFD2_k127_279255_3 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 469.0
HFD2_k127_279255_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 470.0
HFD2_k127_279255_5 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 380.0
HFD2_k127_279255_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000003886 197.0
HFD2_k127_2811275_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 608.0
HFD2_k127_2811275_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 570.0
HFD2_k127_2811275_10 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000003779 156.0
HFD2_k127_2811275_11 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000002236 145.0
HFD2_k127_2811275_12 - - - - 0.0001089 54.0
HFD2_k127_2811275_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 423.0
HFD2_k127_2811275_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 415.0
HFD2_k127_2811275_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 390.0
HFD2_k127_2811275_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 317.0
HFD2_k127_2811275_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 314.0
HFD2_k127_2811275_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
HFD2_k127_2811275_8 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
HFD2_k127_2811275_9 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
HFD2_k127_2856312_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 594.0
HFD2_k127_2856312_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 544.0
HFD2_k127_2856312_10 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 0.000000000000000000000000000000000000000000000000000009757 190.0
HFD2_k127_2856312_11 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000002791 184.0
HFD2_k127_2856312_12 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000002287 157.0
HFD2_k127_2856312_13 - - - - 0.000002558 56.0
HFD2_k127_2856312_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
HFD2_k127_2856312_3 two-component response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 490.0
HFD2_k127_2856312_4 ABC transporter ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 436.0
HFD2_k127_2856312_5 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 392.0
HFD2_k127_2856312_6 Transcriptional regulator IclR K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 359.0
HFD2_k127_2856312_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 309.0
HFD2_k127_2856312_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002463 277.0
HFD2_k127_2856312_9 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
HFD2_k127_2873494_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 2.598e-224 722.0
HFD2_k127_2873494_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 511.0
HFD2_k127_2873494_10 Peptidase family S41 K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000001788 243.0
HFD2_k127_2873494_11 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000621 224.0
HFD2_k127_2873494_12 3-Demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002543 215.0
HFD2_k127_2873494_13 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000000002055 191.0
HFD2_k127_2873494_14 TonB dependent receptor K02014 - - 0.00000000000000000000007855 97.0
HFD2_k127_2873494_15 BON domain - - - 0.0004367 49.0
HFD2_k127_2873494_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 482.0
HFD2_k127_2873494_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 471.0
HFD2_k127_2873494_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 463.0
HFD2_k127_2873494_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 391.0
HFD2_k127_2873494_6 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 410.0
HFD2_k127_2873494_7 Pfam:Methyltransf_6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 366.0
HFD2_k127_2873494_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783,K03815 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 324.0
HFD2_k127_2873494_9 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003808 263.0
HFD2_k127_2889580_0 Amylo-alpha-1,6-glucosidase - - - 0.0 1129.0
HFD2_k127_2889580_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 7.847e-307 949.0
HFD2_k127_2889580_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000001993 165.0
HFD2_k127_2889580_11 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000000000002363 160.0
HFD2_k127_2889580_12 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.000000000000000000000000000000000001578 148.0
HFD2_k127_2889580_13 Fumarate reductase subunit C K00246 - - 0.00000000000000000000000000000000001579 149.0
HFD2_k127_2889580_14 Domain of unknown function (DUF4062) - - - 0.0000000000000000000000000000191 131.0
HFD2_k127_2889580_15 - - - - 0.00000000000000000000000000002134 130.0
HFD2_k127_2889580_16 ABC transporter K06147 - - 0.000000000000000000000000001205 119.0
HFD2_k127_2889580_17 diguanylate cyclase - - - 0.0000000000000000000347 100.0
HFD2_k127_2889580_18 ubiE/COQ5 methyltransferase family - - - 0.00000000000001853 73.0
HFD2_k127_2889580_19 chlorophyll binding - - - 0.00000000000006467 77.0
HFD2_k127_2889580_2 Forkhead-associated protein - - - 8.496e-245 785.0
HFD2_k127_2889580_3 Belongs to the UPF0061 (SELO) family - - - 3.844e-233 733.0
HFD2_k127_2889580_4 Outer membrane efflux protein - - - 1.091e-207 655.0
HFD2_k127_2889580_5 PFAM secretion protein HlyD family protein K02022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 638.0
HFD2_k127_2889580_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 543.0
HFD2_k127_2889580_7 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
HFD2_k127_2889580_8 peptidylprolyl isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 386.0
HFD2_k127_2889580_9 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 339.0
HFD2_k127_2895687_0 Histidine kinase K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 410.0
HFD2_k127_2895687_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 370.0
HFD2_k127_2895687_2 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 329.0
HFD2_k127_2895687_3 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 306.0
HFD2_k127_2895687_4 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000005242 181.0
HFD2_k127_2895687_5 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000001191 173.0
HFD2_k127_2925375_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1079.0
HFD2_k127_2925375_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.284e-276 862.0
HFD2_k127_2925375_2 Binding-protein-dependent transport system inner membrane component K02034 - - 3.295e-198 627.0
HFD2_k127_2925375_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 519.0
HFD2_k127_2925375_4 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 286.0
HFD2_k127_2925375_5 receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004643 284.0
HFD2_k127_2925375_6 FCD K11475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000515 276.0
HFD2_k127_2925375_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 271.0
HFD2_k127_2925375_8 2',5' RNA ligase K01975 - 3.1.4.58 0.0000000000000000000000000000000000008422 154.0
HFD2_k127_2934695_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 5.24e-322 1052.0
HFD2_k127_2934695_1 surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 444.0
HFD2_k127_2934695_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000003695 164.0
HFD2_k127_2938232_0 LapD/MoxY periplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 575.0
HFD2_k127_2938232_1 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 548.0
HFD2_k127_2938232_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
HFD2_k127_2955247_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.474e-271 868.0
HFD2_k127_2955247_1 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 469.0
HFD2_k127_2955247_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 427.0
HFD2_k127_2955247_3 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005064 278.0
HFD2_k127_2955247_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
HFD2_k127_2956679_0 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 3.662e-310 963.0
HFD2_k127_2956679_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 604.0
HFD2_k127_2956679_10 Protein of unknown function (DUF1289) K06938 - - 0.00000000000000004834 87.0
HFD2_k127_2956679_11 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000004052 54.0
HFD2_k127_2956679_12 - - - - 0.000000095 59.0
HFD2_k127_2956679_2 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 501.0
HFD2_k127_2956679_3 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 403.0
HFD2_k127_2956679_4 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 373.0
HFD2_k127_2956679_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 290.0
HFD2_k127_2956679_6 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 274.0
HFD2_k127_2956679_7 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008765 256.0
HFD2_k127_2956679_8 Carboxyl transferase domain K01969 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000006316 198.0
HFD2_k127_2956679_9 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000001976 169.0
HFD2_k127_2959790_0 Putative diguanylate phosphodiesterase - - - 0.0 1156.0
HFD2_k127_2959790_1 His Kinase A (phosphoacceptor) domain - - - 2.9e-305 981.0
HFD2_k127_2959790_2 Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 591.0
HFD2_k127_2959790_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 418.0
HFD2_k127_2959790_4 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 384.0
HFD2_k127_2959790_5 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001198 249.0
HFD2_k127_2966064_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.799e-265 822.0
HFD2_k127_2966064_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 552.0
HFD2_k127_2966064_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 399.0
HFD2_k127_2966064_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 306.0
HFD2_k127_2966064_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000001205 190.0
HFD2_k127_2966064_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000007976 150.0
HFD2_k127_2983970_0 Proton-conducting membrane transporter K12141 - - 4.144e-285 892.0
HFD2_k127_2983970_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.733e-246 794.0
HFD2_k127_2983970_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 550.0
HFD2_k127_2983970_3 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 371.0
HFD2_k127_2983970_4 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005296 276.0
HFD2_k127_2983970_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000008669 153.0
HFD2_k127_299472_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1187.0
HFD2_k127_299472_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 407.0
HFD2_k127_299472_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
HFD2_k127_299472_3 regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000000004783 182.0
HFD2_k127_299472_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000002055 125.0
HFD2_k127_299472_5 - - - - 0.0000001097 53.0
HFD2_k127_29996_0 MMPL family K07003 - - 0.0 1222.0
HFD2_k127_29996_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.998e-265 823.0
HFD2_k127_29996_10 EthD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 331.0
HFD2_k127_29996_11 2-polyprenyl-6-methoxyphenol hydroxylase K17940 - 1.14.13.182 0.0000000000000000000000000000000000001731 158.0
HFD2_k127_29996_2 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 613.0
HFD2_k127_29996_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 569.0
HFD2_k127_29996_4 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 442.0
HFD2_k127_29996_5 oxidoreductase FAD NAD(P)-binding domain protein K03863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 410.0
HFD2_k127_29996_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 368.0
HFD2_k127_29996_7 Rieske [2Fe-2S] domain K22325 - 1.14.15.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 368.0
HFD2_k127_29996_8 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 353.0
HFD2_k127_29996_9 Rieske [2Fe-2S] domain K22325 - 1.14.15.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 331.0
HFD2_k127_3007176_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.911e-270 850.0
HFD2_k127_3007176_1 PFAM Amidase K01426 - 3.5.1.4 3.528e-250 785.0
HFD2_k127_3007176_2 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 584.0
HFD2_k127_3007176_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 523.0
HFD2_k127_3007176_4 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 537.0
HFD2_k127_3007176_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
HFD2_k127_3007176_6 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
HFD2_k127_3007176_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000009467 170.0
HFD2_k127_3007176_8 Cytochrome c - - - 0.00000000000000346 88.0
HFD2_k127_3007176_9 Phosphopantetheine attachment site - - - 0.0000006071 61.0
HFD2_k127_3014476_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1452.0
HFD2_k127_3014476_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.116e-306 947.0
HFD2_k127_3014476_10 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000007737 214.0
HFD2_k127_3014476_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000000001681 185.0
HFD2_k127_3014476_12 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000000000000000008971 132.0
HFD2_k127_3014476_13 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000006911 111.0
HFD2_k127_3014476_14 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000008232 58.0
HFD2_k127_3014476_15 - - - - 0.0000006321 57.0
HFD2_k127_3014476_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.193e-257 799.0
HFD2_k127_3014476_3 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 422.0
HFD2_k127_3014476_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 340.0
HFD2_k127_3014476_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 334.0
HFD2_k127_3014476_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 319.0
HFD2_k127_3014476_7 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 246.0
HFD2_k127_3014476_8 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000001891 227.0
HFD2_k127_3014476_9 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000005655 239.0
HFD2_k127_3014812_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 441.0
HFD2_k127_3014812_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 446.0
HFD2_k127_3014812_10 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000000002909 175.0
HFD2_k127_3014812_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000000003864 151.0
HFD2_k127_3014812_2 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 376.0
HFD2_k127_3014812_3 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 346.0
HFD2_k127_3014812_4 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 342.0
HFD2_k127_3014812_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003247 287.0
HFD2_k127_3014812_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000422 249.0
HFD2_k127_3014812_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000019 253.0
HFD2_k127_3014812_8 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000001652 214.0
HFD2_k127_3014812_9 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000001235 180.0
HFD2_k127_3017755_0 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 531.0
HFD2_k127_3017755_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 304.0
HFD2_k127_3017755_2 Cytochrome c class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 292.0
HFD2_k127_3017755_3 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007541 261.0
HFD2_k127_3017755_4 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000001927 168.0
HFD2_k127_3017755_5 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000001931 130.0
HFD2_k127_3017755_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000002976 66.0
HFD2_k127_3025016_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 477.0
HFD2_k127_3025016_1 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 439.0
HFD2_k127_3025016_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 370.0
HFD2_k127_3025016_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005564 249.0
HFD2_k127_3025016_4 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000002747 171.0
HFD2_k127_3025016_5 - - - - 0.000000000000000000000000000000000000000001982 162.0
HFD2_k127_3025016_6 Major Facilitator Superfamily - - - 0.00000000000000000000007035 98.0
HFD2_k127_3066419_0 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 461.0
HFD2_k127_3066419_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001703 291.0
HFD2_k127_3066419_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000001173 188.0
HFD2_k127_3066419_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000938 121.0
HFD2_k127_3066419_4 B-1 B cell differentiation - - - 0.00000000000008827 83.0
HFD2_k127_3066593_0 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 586.0
HFD2_k127_3066593_1 Diguanylate cyclase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 538.0
HFD2_k127_3066593_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 458.0
HFD2_k127_3069946_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1239.0
HFD2_k127_3069946_1 Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation K05549 - 1.14.12.10 7.416e-266 822.0
HFD2_k127_3069946_10 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 383.0
HFD2_k127_3069946_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 373.0
HFD2_k127_3069946_12 Ring hydroxylating subunit beta family protein 3 K16303 - 1.14.12.25 0.0000000000000000000000000000000000000000000000000000000000000000004124 251.0
HFD2_k127_3069946_13 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
HFD2_k127_3069946_14 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000107 106.0
HFD2_k127_3069946_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 2.483e-259 808.0
HFD2_k127_3069946_3 Short-chain dehydrogenase reductase sdr - - - 7.027e-236 754.0
HFD2_k127_3069946_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 1.29e-221 702.0
HFD2_k127_3069946_5 acetyl-coa acetyltransferase - - - 3.681e-214 676.0
HFD2_k127_3069946_6 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 510.0
HFD2_k127_3069946_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 513.0
HFD2_k127_3069946_8 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 502.0
HFD2_k127_3069946_9 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 449.0
HFD2_k127_3106682_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 384.0
HFD2_k127_3106682_1 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 361.0
HFD2_k127_3106682_2 Organic Hydroperoxide Resistance Protein - - - 0.00000000000000000000000000000000000000000000000000000002506 208.0
HFD2_k127_3106682_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000001848 192.0
HFD2_k127_3106682_4 ABC transporter K06158 - - 0.000000000000000000000000000000000000004158 150.0
HFD2_k127_3106682_5 Pathogenicity locus K07343 - - 0.00000000000000000009625 97.0
HFD2_k127_3120662_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0 1119.0
HFD2_k127_3120662_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 480.0
HFD2_k127_3120662_10 Tim44 - - - 0.000000000000000000000000000000000000000000000000000003724 196.0
HFD2_k127_3120662_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 433.0
HFD2_k127_3120662_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 371.0
HFD2_k127_3120662_4 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 345.0
HFD2_k127_3120662_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 334.0
HFD2_k127_3120662_6 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 318.0
HFD2_k127_3120662_7 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HFD2_k127_3120662_8 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005349 259.0
HFD2_k127_3120662_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002439 261.0
HFD2_k127_3125280_0 TonB dependent receptor K16090 - - 1.552e-219 695.0
HFD2_k127_3125280_1 penicillin-binding protein K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 484.0
HFD2_k127_3125280_2 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000000000000000000001393 170.0
HFD2_k127_3130342_0 histidine kinase A domain protein - - - 0.0 1147.0
HFD2_k127_3130342_1 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 614.0
HFD2_k127_3130342_2 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 468.0
HFD2_k127_3130342_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000002494 183.0
HFD2_k127_3130342_4 - - - - 0.00000000000005093 75.0
HFD2_k127_3138231_0 RNB K01147 - 3.1.13.1 0.0 1078.0
HFD2_k127_3138231_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 429.0
HFD2_k127_3138231_2 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 419.0
HFD2_k127_3138231_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 360.0
HFD2_k127_3138231_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 341.0
HFD2_k127_3138231_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
HFD2_k127_3138231_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001252 272.0
HFD2_k127_3138231_7 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005651 246.0
HFD2_k127_3138231_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
HFD2_k127_3138231_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000001641 184.0
HFD2_k127_3139299_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.466e-282 899.0
HFD2_k127_3139299_1 protein conserved in bacteria K07793 - - 1.525e-279 876.0
HFD2_k127_3139299_10 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004073 274.0
HFD2_k127_3139299_11 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000023 248.0
HFD2_k127_3139299_12 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000000000000011 194.0
HFD2_k127_3139299_13 PFAM aromatic-ring-hydroxylating dioxygenase beta subunit - - - 0.00000000000000000000000000000000000000000000000000399 185.0
HFD2_k127_3139299_2 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 1.787e-247 777.0
HFD2_k127_3139299_3 dioxygenase, alpha - - - 2.353e-225 706.0
HFD2_k127_3139299_4 PFAM Extracellular ligand-binding receptor - - - 1.765e-199 631.0
HFD2_k127_3139299_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 516.0
HFD2_k127_3139299_6 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 387.0
HFD2_k127_3139299_7 Short-chain dehydrogenase reductase sdr K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 361.0
HFD2_k127_3139299_8 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 328.0
HFD2_k127_3139299_9 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 301.0
HFD2_k127_3153091_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 8.976e-203 637.0
HFD2_k127_3153091_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 404.0
HFD2_k127_3153091_2 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
HFD2_k127_3153091_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 373.0
HFD2_k127_3153091_4 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000005203 186.0
HFD2_k127_3153091_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000356 134.0
HFD2_k127_3153091_6 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000003026 130.0
HFD2_k127_3156625_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 4.016e-204 642.0
HFD2_k127_3156625_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 541.0
HFD2_k127_3156625_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 538.0
HFD2_k127_3156625_3 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 537.0
HFD2_k127_3156625_4 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
HFD2_k127_3156625_5 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 404.0
HFD2_k127_3156625_6 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000000002617 233.0
HFD2_k127_3156625_7 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000004271 119.0
HFD2_k127_3177996_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.934e-245 783.0
HFD2_k127_3177996_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 556.0
HFD2_k127_3177996_2 Extracellular liganD-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 451.0
HFD2_k127_3177996_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 388.0
HFD2_k127_3177996_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 344.0
HFD2_k127_3177996_5 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 304.0
HFD2_k127_3177996_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 310.0
HFD2_k127_3177996_7 - - - - 0.000000000000000001754 91.0
HFD2_k127_3178884_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.948e-275 859.0
HFD2_k127_3178884_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 538.0
HFD2_k127_3178884_2 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 524.0
HFD2_k127_3178884_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 347.0
HFD2_k127_3178884_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001484 274.0
HFD2_k127_3178884_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000001707 227.0
HFD2_k127_3178884_6 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000000000000000000000000000000006346 200.0
HFD2_k127_3178884_7 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000000000002866 129.0
HFD2_k127_3249771_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.944e-199 626.0
HFD2_k127_3249771_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 424.0
HFD2_k127_3249771_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 362.0
HFD2_k127_3249771_3 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 365.0
HFD2_k127_3249771_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006363 261.0
HFD2_k127_3249771_5 Late competence development protein ComFB - - - 0.00000000000000000000000000000123 129.0
HFD2_k127_3312775_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.144e-298 927.0
HFD2_k127_3312775_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 570.0
HFD2_k127_3312775_2 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 317.0
HFD2_k127_3312775_3 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
HFD2_k127_3312775_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
HFD2_k127_3312775_5 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000009194 235.0
HFD2_k127_3312775_6 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000002198 208.0
HFD2_k127_3312775_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000001682 123.0
HFD2_k127_3346632_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 2.225e-213 680.0
HFD2_k127_3346632_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 471.0
HFD2_k127_3346632_2 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000135 202.0
HFD2_k127_3346632_3 - - - - 0.0000000000000000000000000000000001429 137.0
HFD2_k127_3346632_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000001782 124.0
HFD2_k127_3346632_5 - - - - 0.000000000000000000003994 100.0
HFD2_k127_3380868_0 PAS fold - - - 1.127e-228 760.0
HFD2_k127_3380868_1 Response regulator receiver - - - 3.036e-197 627.0
HFD2_k127_3380868_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 611.0
HFD2_k127_3380868_3 Glycosyltransferase Family 4 K14335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 342.0
HFD2_k127_3380868_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 314.0
HFD2_k127_3380868_5 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000001102 214.0
HFD2_k127_3380868_6 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000000000000000000000000000000000000000000002269 217.0
HFD2_k127_3380868_7 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000001191 153.0
HFD2_k127_3380868_8 PAP2 superfamily K19302 - 3.6.1.27 0.000000000000000000000000000000000003454 158.0
HFD2_k127_3380868_9 Transglycosylase associated protein - - - 0.00000000000000000000000000000000001159 142.0
HFD2_k127_3386522_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 1.661e-208 666.0
HFD2_k127_3386522_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 306.0
HFD2_k127_3386522_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 289.0
HFD2_k127_3386522_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000002052 199.0
HFD2_k127_3386522_4 Maltoporin (phage lambda and maltose receptor) K02024 - - 0.00000000000000000000000000000000000000000000000000006166 197.0
HFD2_k127_3386522_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000008478 138.0
HFD2_k127_3407238_0 PFAM Tannase and feruloyl esterase K21105 - 3.1.1.102 8.358e-211 666.0
HFD2_k127_3407238_1 Protein of unknown function (DUF1688) - - - 9.272e-202 635.0
HFD2_k127_3407238_2 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000004323 162.0
HFD2_k127_3421491_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 3.302e-210 662.0
HFD2_k127_3421491_1 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 611.0
HFD2_k127_3421491_10 LemA family K03744 - - 0.000000002317 66.0
HFD2_k127_3421491_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 381.0
HFD2_k127_3421491_3 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 366.0
HFD2_k127_3421491_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003398 251.0
HFD2_k127_3421491_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000889 193.0
HFD2_k127_3421491_6 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000007927 178.0
HFD2_k127_3421491_7 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000006947 177.0
HFD2_k127_3421491_8 Protein of unknown function (DUF3999) - - - 0.00000000000000000000000000000000000000008931 168.0
HFD2_k127_3421491_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000001095 67.0
HFD2_k127_3423373_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.232e-299 947.0
HFD2_k127_3423373_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.628e-269 833.0
HFD2_k127_3423373_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 588.0
HFD2_k127_3423373_3 EamA-like transporter family K15269 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 448.0
HFD2_k127_3423373_4 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 309.0
HFD2_k127_3423373_5 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003982 265.0
HFD2_k127_3423373_6 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005222 265.0
HFD2_k127_3423373_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000001007 193.0
HFD2_k127_3464382_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.639e-230 728.0
HFD2_k127_3464382_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 530.0
HFD2_k127_3464382_2 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 364.0
HFD2_k127_3464382_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
HFD2_k127_3464382_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 324.0
HFD2_k127_3464382_5 Iron-storage protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007117 272.0
HFD2_k127_3464382_6 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004676 269.0
HFD2_k127_3464382_7 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HFD2_k127_3464382_8 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000707 141.0
HFD2_k127_354200_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.757e-319 988.0
HFD2_k127_354200_1 Mo-co oxidoreductase dimerisation domain K17225 - - 1.844e-260 807.0
HFD2_k127_354200_10 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
HFD2_k127_354200_11 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000000007972 185.0
HFD2_k127_354200_12 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000009467 195.0
HFD2_k127_354200_13 Protein of unknown function (DUF3149) - - - 0.0000000000000001089 81.0
HFD2_k127_354200_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 550.0
HFD2_k127_354200_3 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 456.0
HFD2_k127_354200_4 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 443.0
HFD2_k127_354200_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 331.0
HFD2_k127_354200_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 304.0
HFD2_k127_354200_7 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000436 295.0
HFD2_k127_354200_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000002682 234.0
HFD2_k127_354200_9 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000002193 211.0
HFD2_k127_3545417_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 531.0
HFD2_k127_3545417_1 - - - - 0.00000000000000000007816 100.0
HFD2_k127_3545417_2 serine threonine protein phosphatase - - - 0.0000000000001673 82.0
HFD2_k127_3545417_3 Inner membrane component of T3SS, cytoplasmic domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000004232 59.0
HFD2_k127_3545417_4 serine threonine protein kinase - - - 0.0001802 55.0
HFD2_k127_357182_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 594.0
HFD2_k127_357182_1 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 586.0
HFD2_k127_357182_10 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000001365 214.0
HFD2_k127_357182_11 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000004589 139.0
HFD2_k127_357182_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002252 141.0
HFD2_k127_357182_13 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000001057 91.0
HFD2_k127_357182_14 Protein required for attachment to host cells - - - 0.00000000000000007096 86.0
HFD2_k127_357182_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 586.0
HFD2_k127_357182_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 573.0
HFD2_k127_357182_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 512.0
HFD2_k127_357182_5 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 413.0
HFD2_k127_357182_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 413.0
HFD2_k127_357182_7 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 375.0
HFD2_k127_357182_8 Phage plasmid primase P4 family K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
HFD2_k127_357182_9 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000001927 242.0
HFD2_k127_3577923_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 506.0
HFD2_k127_3577923_1 3-beta hydroxysteroid dehydrogenase/isomerase family K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
HFD2_k127_3577923_2 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 449.0
HFD2_k127_3577923_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000008666 187.0
HFD2_k127_3577923_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000000281 183.0
HFD2_k127_3577923_5 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000000000000000166 108.0
HFD2_k127_3581393_0 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
HFD2_k127_3581393_1 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009957 278.0
HFD2_k127_3581393_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000001338 122.0
HFD2_k127_3581393_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000003141 254.0
HFD2_k127_3581393_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 240.0
HFD2_k127_3581393_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000002031 243.0
HFD2_k127_3581393_5 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000003018 225.0
HFD2_k127_3581393_6 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000000000181 201.0
HFD2_k127_3581393_7 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000007447 177.0
HFD2_k127_3581393_8 membrane - - - 0.000000000000000000000000000000000000000000008528 171.0
HFD2_k127_3581393_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000625 158.0
HFD2_k127_3582169_0 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 1.73e-246 764.0
HFD2_k127_3582169_1 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 3.417e-209 661.0
HFD2_k127_3582169_2 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
HFD2_k127_3582169_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001998 304.0
HFD2_k127_3582169_4 PFAM CreA family protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 232.0
HFD2_k127_3582169_5 Protein kinase domain K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003078 243.0
HFD2_k127_3582169_6 Domain of unknown function (DUF4864) - - - 0.00000000318 58.0
HFD2_k127_3610192_0 Dehydrogenase K00382 - 1.8.1.4 7.825e-311 960.0
HFD2_k127_3610192_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 4.405e-239 750.0
HFD2_k127_3610192_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 2.325e-223 694.0
HFD2_k127_3611310_0 glutamine synthetase K01915 - 6.3.1.2 6.137e-266 822.0
HFD2_k127_3611310_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 9.647e-254 788.0
HFD2_k127_3611310_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 2.18e-207 648.0
HFD2_k127_3611310_3 FAD binding domain K09471 - - 4.306e-194 614.0
HFD2_k127_3611310_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 593.0
HFD2_k127_3611310_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 482.0
HFD2_k127_3611310_6 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 400.0
HFD2_k127_3611310_7 transport system permease K11075 - - 0.00000000000000000000000000000000000000004928 170.0
HFD2_k127_3615680_0 Glycosyl hydrolases family 2, sugar binding domain - - - 1.073e-267 853.0
HFD2_k127_3615680_1 Glycoside Hydrolase - - - 9.986e-233 732.0
HFD2_k127_3615680_10 Transcriptional regulator - - - 0.00000000001796 74.0
HFD2_k127_3615680_11 Belongs to the transketolase family K00615 - 2.2.1.1 0.000001078 61.0
HFD2_k127_3615680_12 Psort location Cytoplasmic, score - - - 0.000008486 56.0
HFD2_k127_3615680_2 xylulose kinase K00854 - 2.7.1.17 1.128e-197 632.0
HFD2_k127_3615680_3 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 2.526e-197 624.0
HFD2_k127_3615680_4 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 472.0
HFD2_k127_3615680_5 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 394.0
HFD2_k127_3615680_6 PFAM ROK family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 364.0
HFD2_k127_3615680_7 Glycosyl hydrolases family 43 K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 327.0
HFD2_k127_3615680_8 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004076 215.0
HFD2_k127_3615680_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000004032 183.0
HFD2_k127_3620827_0 Ferrous iron transport protein B K04759 - - 5.813e-305 944.0
HFD2_k127_3620827_1 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 494.0
HFD2_k127_3620827_10 - - - - 0.0000000000001419 78.0
HFD2_k127_3620827_11 - - - - 0.00000003297 67.0
HFD2_k127_3620827_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 429.0
HFD2_k127_3620827_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 389.0
HFD2_k127_3620827_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 355.0
HFD2_k127_3620827_5 cytochrome C peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 344.0
HFD2_k127_3620827_6 PFAM ABC transporter related K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
HFD2_k127_3620827_7 FMN_bind - - - 0.00000000000000000000000000000000000000000000000000000005738 202.0
HFD2_k127_3620827_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000008794 124.0
HFD2_k127_3620827_9 iron ion homeostasis K04758 - - 0.0000000000000000000000000406 109.0
HFD2_k127_3624740_0 ABC transporter K15738 - - 2.035e-273 855.0
HFD2_k127_3624740_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.202e-201 635.0
HFD2_k127_3624740_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 554.0
HFD2_k127_3624740_3 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 303.0
HFD2_k127_3624740_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000374 263.0
HFD2_k127_3624740_5 Belongs to the ABC transporter superfamily K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001872 248.0
HFD2_k127_3624740_6 SURF4 family K15977 - - 0.00000000000000000000000000000000000000000000003244 174.0
HFD2_k127_3624740_7 - - - - 0.00000008952 63.0
HFD2_k127_3626615_0 Peptidase family M3 K01284 - 3.4.15.5 1.768e-303 944.0
HFD2_k127_3626615_1 Prolyl oligopeptidase K01322 - 3.4.21.26 1.836e-296 927.0
HFD2_k127_3626615_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 556.0
HFD2_k127_3626615_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 469.0
HFD2_k127_3626615_4 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 292.0
HFD2_k127_3626615_5 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009249 255.0
HFD2_k127_3626615_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
HFD2_k127_3626615_7 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000000403 112.0
HFD2_k127_3636547_0 Patatin-like phospholipase K07001 - - 1.272e-272 865.0
HFD2_k127_3636547_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 529.0
HFD2_k127_3636547_10 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000006128 228.0
HFD2_k127_3636547_11 tryptophan synthase subunit beta - - - 0.00000000000000000000000000000000005321 136.0
HFD2_k127_3636547_12 STAS domain K07122 - - 0.0000000000000000000000001656 109.0
HFD2_k127_3636547_13 type VI secretion system effector K11903 - - 0.00000007101 63.0
HFD2_k127_3636547_14 type VI secretion system effector, Hcp1 family K11903 - - 0.000031 53.0
HFD2_k127_3636547_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 396.0
HFD2_k127_3636547_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 316.0
HFD2_k127_3636547_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 309.0
HFD2_k127_3636547_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 312.0
HFD2_k127_3636547_6 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
HFD2_k127_3636547_7 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000419 303.0
HFD2_k127_3636547_8 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001621 272.0
HFD2_k127_3636547_9 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003739 254.0
HFD2_k127_3650839_0 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002428 266.0
HFD2_k127_3650839_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HFD2_k127_3650839_2 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000001931 218.0
HFD2_k127_3650839_3 abc-type tungstate transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000001137 211.0
HFD2_k127_3650839_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000001415 143.0
HFD2_k127_3650839_5 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000008549 114.0
HFD2_k127_3713788_0 Transporter - - - 1.443e-301 941.0
HFD2_k127_3713788_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.021e-279 869.0
HFD2_k127_3713788_2 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 554.0
HFD2_k127_3713788_3 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 533.0
HFD2_k127_3713788_4 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 531.0
HFD2_k127_3713788_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 502.0
HFD2_k127_3713788_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 477.0
HFD2_k127_3713788_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 426.0
HFD2_k127_3713788_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000149 222.0
HFD2_k127_3726546_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 2.482e-257 813.0
HFD2_k127_3726546_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 533.0
HFD2_k127_3726546_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 369.0
HFD2_k127_3726546_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000001729 198.0
HFD2_k127_3726546_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000002153 81.0
HFD2_k127_3726546_5 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000002085 64.0
HFD2_k127_3736759_0 Na+/Pi-cotransporter K03324 - - 2.538e-266 829.0
HFD2_k127_3736759_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.608e-244 760.0
HFD2_k127_3736759_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 2.428e-200 646.0
HFD2_k127_3736759_3 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 2.237e-194 610.0
HFD2_k127_3736759_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 355.0
HFD2_k127_3736759_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
HFD2_k127_3736759_6 TIGRFAM phosphonate degradation operons associated HDIG domain protein K21196 - 1.13.11.78 0.000000000000000000000000000000000000000000000000000000000000000000000000004742 258.0
HFD2_k127_3736759_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000003967 212.0
HFD2_k127_3745091_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1546.0
HFD2_k127_3745091_1 4Fe-4S dicluster domain - - - 0.0 1057.0
HFD2_k127_3745091_10 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002697 293.0
HFD2_k127_3745091_11 - - - - 0.0000000000000000000000000000000000000000000001118 171.0
HFD2_k127_3745091_2 formate dehydrogenase K00122 - 1.17.1.9 2.87e-287 890.0
HFD2_k127_3745091_3 Single cache domain 3 K02482 - 2.7.13.3 3.026e-238 749.0
HFD2_k127_3745091_4 Sigma-54 interaction domain - - - 7.924e-224 701.0
HFD2_k127_3745091_5 PBP superfamily domain K07219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 525.0
HFD2_k127_3745091_6 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 392.0
HFD2_k127_3745091_7 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 324.0
HFD2_k127_3745091_8 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 323.0
HFD2_k127_3745091_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 289.0
HFD2_k127_3772641_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 559.0
HFD2_k127_3772641_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 548.0
HFD2_k127_3772641_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002763 166.0
HFD2_k127_3772641_11 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000008213 156.0
HFD2_k127_3772641_12 - - - - 0.00000000000000000001626 103.0
HFD2_k127_3772641_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 476.0
HFD2_k127_3772641_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 468.0
HFD2_k127_3772641_4 Belongs to the enoyl-CoA hydratase isomerase family K20036 - 4.2.1.155 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 392.0
HFD2_k127_3772641_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 406.0
HFD2_k127_3772641_6 AMP-binding enzyme K12508 - 6.2.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 369.0
HFD2_k127_3772641_7 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 352.0
HFD2_k127_3772641_8 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 345.0
HFD2_k127_3772641_9 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000000000000000000000003133 230.0
HFD2_k127_3785335_0 ABC transporter substrate-binding protein K01999 - - 3.87e-251 777.0
HFD2_k127_3785335_1 belongs to the aldehyde dehydrogenase family K00130,K00146 - 1.2.1.39,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 542.0
HFD2_k127_3785335_10 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000001857 116.0
HFD2_k127_3785335_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 533.0
HFD2_k127_3785335_3 PFAM iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 470.0
HFD2_k127_3785335_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 458.0
HFD2_k127_3785335_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 417.0
HFD2_k127_3785335_6 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 399.0
HFD2_k127_3785335_7 PFAM intradiol ring-cleavage dioxygenase K04098 - 1.13.11.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 402.0
HFD2_k127_3785335_8 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 354.0
HFD2_k127_3785335_9 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
HFD2_k127_3793310_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.17e-286 883.0
HFD2_k127_3793310_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 8.126e-266 822.0
HFD2_k127_3793310_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 471.0
HFD2_k127_3793310_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 302.0
HFD2_k127_3793310_4 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000002129 113.0
HFD2_k127_3793310_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000001124 53.0
HFD2_k127_3813686_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 5.87e-206 645.0
HFD2_k127_3813686_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 606.0
HFD2_k127_3813686_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 523.0
HFD2_k127_3813686_3 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 437.0
HFD2_k127_3813686_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 394.0
HFD2_k127_3813686_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 377.0
HFD2_k127_3813686_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000596 265.0
HFD2_k127_3813686_7 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000065 169.0
HFD2_k127_3838151_0 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 326.0
HFD2_k127_3838151_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000001556 218.0
HFD2_k127_3838151_2 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000004179 233.0
HFD2_k127_3838151_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000004446 212.0
HFD2_k127_3838151_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000003999 188.0
HFD2_k127_3838151_5 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000006314 109.0
HFD2_k127_3838151_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000009872 84.0
HFD2_k127_3844918_0 FtsX-like permease family K02004 - - 7.989e-286 891.0
HFD2_k127_3844918_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.976e-262 814.0
HFD2_k127_3844918_2 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 479.0
HFD2_k127_3844918_3 Cys Met metabolism pyridoxal-phosphate-dependent K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 366.0
HFD2_k127_3844918_4 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
HFD2_k127_3865360_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.918e-269 834.0
HFD2_k127_3865360_1 GAF modulated sigma54 specific transcriptional regulator, Fis family K21405 - - 2.002e-216 681.0
HFD2_k127_3865360_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000001301 203.0
HFD2_k127_3865360_2 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 478.0
HFD2_k127_3865360_3 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 470.0
HFD2_k127_3865360_4 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 463.0
HFD2_k127_3865360_5 Beta-ribofuranosylaminobenzene 5-phosphate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 375.0
HFD2_k127_3865360_6 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 365.0
HFD2_k127_3865360_7 triphosphoribosyl-dephospho-CoA K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 343.0
HFD2_k127_3865360_8 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 305.0
HFD2_k127_3865360_9 dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000006971 233.0
HFD2_k127_3873543_0 56kDa selenium binding protein (SBP56) K17285 - - 8.119e-264 819.0
HFD2_k127_3873543_1 Cytochrome c oxidase accessory protein CcoG - - - 7.871e-204 644.0
HFD2_k127_3873543_10 ABC transporter - - - 0.0000000000000000000000000000000000000000000004961 186.0
HFD2_k127_3873543_11 Membrane - - - 0.00000000000000000000000154 121.0
HFD2_k127_3873543_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 3.959e-197 619.0
HFD2_k127_3873543_3 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 573.0
HFD2_k127_3873543_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 563.0
HFD2_k127_3873543_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 436.0
HFD2_k127_3873543_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 433.0
HFD2_k127_3873543_7 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 306.0
HFD2_k127_3873543_8 - - - - 0.000000000000000000000000000000000000000000000000000000000001501 233.0
HFD2_k127_3873543_9 AraC family - - - 0.0000000000000000000000000000000000000000000000000000001019 196.0
HFD2_k127_3897515_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.255e-241 762.0
HFD2_k127_3897515_1 Acetyl-coenzyme A transporter 1 K08218 - - 9.131e-210 659.0
HFD2_k127_3897515_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000002987 146.0
HFD2_k127_3897515_11 Cytochrome c, class I - - - 0.00000000000000000000128 100.0
HFD2_k127_3897515_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 570.0
HFD2_k127_3897515_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 434.0
HFD2_k127_3897515_4 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 402.0
HFD2_k127_3897515_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 347.0
HFD2_k127_3897515_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
HFD2_k127_3897515_7 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
HFD2_k127_3897515_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008662 252.0
HFD2_k127_3897515_9 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000556 143.0
HFD2_k127_392157_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 420.0
HFD2_k127_392157_1 - - - - 0.000000000000000000000000000000000000000000000000000007244 196.0
HFD2_k127_392157_2 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000000000000000005226 178.0
HFD2_k127_3955456_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.306e-278 862.0
HFD2_k127_3955456_1 His Kinase A (phosphoacceptor) domain - - - 2.617e-258 825.0
HFD2_k127_3955456_10 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 329.0
HFD2_k127_3955456_11 TOBE domain K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 325.0
HFD2_k127_3955456_12 LysR substrate binding domain K16516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008773 259.0
HFD2_k127_3955456_13 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000004262 248.0
HFD2_k127_3955456_14 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000005029 182.0
HFD2_k127_3955456_15 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000003545 131.0
HFD2_k127_3955456_16 - - - - 0.0000000000000000001047 98.0
HFD2_k127_3955456_17 Protein of unknown function (DUF3606) - - - 0.0000005871 56.0
HFD2_k127_3955456_18 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000004884 52.0
HFD2_k127_3955456_19 Protein of unknown function (DUF1161) - - - 0.00001072 57.0
HFD2_k127_3955456_2 PA domain - - - 2.513e-222 707.0
HFD2_k127_3955456_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 419.0
HFD2_k127_3955456_4 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 383.0
HFD2_k127_3955456_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 378.0
HFD2_k127_3955456_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 379.0
HFD2_k127_3955456_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
HFD2_k127_3955456_8 TIGRFAM molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 347.0
HFD2_k127_3955456_9 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 324.0
HFD2_k127_4027544_0 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 593.0
HFD2_k127_4027544_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 502.0
HFD2_k127_4027544_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000002824 215.0
HFD2_k127_4027544_3 Bacterial protein of unknown function (DUF883) - - - 0.00000000003941 67.0
HFD2_k127_4027544_4 Dienelactone hydrolase family - - - 0.000000001597 67.0
HFD2_k127_4027544_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000003765 60.0
HFD2_k127_403130_0 - - - - 9.116e-208 659.0
HFD2_k127_403130_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 570.0
HFD2_k127_403130_2 3-beta hydroxysteroid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 517.0
HFD2_k127_403130_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 511.0
HFD2_k127_403130_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 491.0
HFD2_k127_403130_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 468.0
HFD2_k127_403130_6 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 402.0
HFD2_k127_403130_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008702 282.0
HFD2_k127_403130_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HFD2_k127_403130_9 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000002293 140.0
HFD2_k127_4055034_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 548.0
HFD2_k127_4055034_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 379.0
HFD2_k127_4055034_2 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 300.0
HFD2_k127_4055034_3 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000001577 214.0
HFD2_k127_4055034_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000000156 162.0
HFD2_k127_407270_0 Domain of unknown function (DUF4982) - - - 0.0 1101.0
HFD2_k127_407270_1 Alpha-L-fucosidase K01206 - 3.2.1.51 8.648e-276 896.0
HFD2_k127_407270_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.13e-231 728.0
HFD2_k127_4075097_0 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 559.0
HFD2_k127_4075097_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 549.0
HFD2_k127_4075097_2 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 481.0
HFD2_k127_4075097_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 343.0
HFD2_k127_4075097_4 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000002011 89.0
HFD2_k127_4075097_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0005538 45.0
HFD2_k127_4088888_0 Belongs to the GPI family K01810 - 5.3.1.9 1.675e-287 906.0
HFD2_k127_4088888_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 501.0
HFD2_k127_4088888_2 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000001138 220.0
HFD2_k127_4088888_3 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000004339 175.0
HFD2_k127_4088888_4 Tetratricopeptide repeat - - - 0.000000000000000000001194 108.0
HFD2_k127_4095047_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1507.0
HFD2_k127_4095047_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 398.0
HFD2_k127_4095047_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139,K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 410.0
HFD2_k127_4095047_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 393.0
HFD2_k127_4095047_4 Protein of unknown function (DUF3455) - - - 0.000000002186 63.0
HFD2_k127_4098584_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1463.0
HFD2_k127_4098584_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 458.0
HFD2_k127_4098584_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
HFD2_k127_4103412_0 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 505.0
HFD2_k127_4103412_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 423.0
HFD2_k127_4103412_10 - - - - 0.0000000000000000001686 93.0
HFD2_k127_4103412_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 415.0
HFD2_k127_4103412_3 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 359.0
HFD2_k127_4103412_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003093 278.0
HFD2_k127_4103412_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000003715 254.0
HFD2_k127_4103412_6 COG0811 Biopolymer transport proteins - - - 0.00000000000000000000000000000000000000000000000000001085 196.0
HFD2_k127_4103412_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001422 161.0
HFD2_k127_4103412_8 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000004396 145.0
HFD2_k127_4103412_9 biopolymer transport protein - - - 0.0000000000000000000000003935 111.0
HFD2_k127_4120961_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 591.0
HFD2_k127_4120961_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004168 248.0
HFD2_k127_4120961_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000174 181.0
HFD2_k127_4120961_3 SnoaL-like domain K06893 - - 0.000000000000000000000000000000004939 145.0
HFD2_k127_4131768_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.648e-296 915.0
HFD2_k127_4131768_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.084e-232 726.0
HFD2_k127_4131768_10 Cytochrome c K17223 - - 0.0000000000000000000000000000000001555 154.0
HFD2_k127_4131768_11 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000002872 109.0
HFD2_k127_4131768_2 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 606.0
HFD2_k127_4131768_3 C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 317.0
HFD2_k127_4131768_4 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007831 281.0
HFD2_k127_4131768_5 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003978 276.0
HFD2_k127_4131768_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000006429 190.0
HFD2_k127_4131768_7 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000001403 204.0
HFD2_k127_4131768_8 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000001413 180.0
HFD2_k127_4131768_9 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000001799 145.0
HFD2_k127_4135413_0 thiolester hydrolase activity - - - 0.0 1013.0
HFD2_k127_4135413_1 Domain of unknown function (DUF3362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 430.0
HFD2_k127_4135413_2 ABC transporter transmembrane region K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 421.0
HFD2_k127_4153894_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.857e-286 902.0
HFD2_k127_4153894_1 Major Facilitator - - - 2.342e-223 698.0
HFD2_k127_4153894_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 569.0
HFD2_k127_4153894_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 486.0
HFD2_k127_4153894_4 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 466.0
HFD2_k127_4153894_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 365.0
HFD2_k127_4153894_6 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000001404 174.0
HFD2_k127_4153894_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000002173 171.0
HFD2_k127_4153894_8 cheY-homologous receiver domain - - - 0.000000000003871 68.0
HFD2_k127_4169691_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 614.0
HFD2_k127_4169691_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 422.0
HFD2_k127_4169691_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
HFD2_k127_4169691_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 337.0
HFD2_k127_4169691_4 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
HFD2_k127_4169691_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
HFD2_k127_4169691_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000001231 59.0
HFD2_k127_4169691_7 - - - - 0.000001116 53.0
HFD2_k127_4215187_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.988e-266 823.0
HFD2_k127_4215187_1 peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 473.0
HFD2_k127_4215187_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 461.0
HFD2_k127_4215187_3 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 398.0
HFD2_k127_4215187_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 321.0
HFD2_k127_4215187_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 290.0
HFD2_k127_4215187_6 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009671 278.0
HFD2_k127_4215187_7 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000002547 167.0
HFD2_k127_4215187_8 AraC-like ligand binding domain - - - 0.00000000000000000000000008406 108.0
HFD2_k127_4247800_0 PFAM Mammalian cell entry related domain protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 509.0
HFD2_k127_4247800_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 451.0
HFD2_k127_4247800_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 449.0
HFD2_k127_4247800_3 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 331.0
HFD2_k127_4247800_4 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 307.0
HFD2_k127_4247800_5 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000002031 229.0
HFD2_k127_4247800_6 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000002719 197.0
HFD2_k127_4247800_7 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000001674 101.0
HFD2_k127_4247800_8 Paraquat-inducible protein A K03808 - - 0.00000009179 63.0
HFD2_k127_4278113_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1102.0
HFD2_k127_4278113_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 5.536e-249 777.0
HFD2_k127_4278113_2 Domain of unknown function (DUF4178) - - - 1.93e-204 649.0
HFD2_k127_4278113_3 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 619.0
HFD2_k127_4278113_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 584.0
HFD2_k127_4278113_5 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 413.0
HFD2_k127_4278113_6 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 293.0
HFD2_k127_4278113_7 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000000000000001052 162.0
HFD2_k127_4278113_8 Domain of Unknown Function (DUF350) - - - 0.000000000000000000000000002746 115.0
HFD2_k127_4278113_9 - - - - 0.00000000043 71.0
HFD2_k127_42824_0 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520,K21739 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 589.0
HFD2_k127_42824_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 568.0
HFD2_k127_42824_10 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 330.0
HFD2_k127_42824_11 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HFD2_k127_42824_12 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000009661 208.0
HFD2_k127_42824_13 DinB family - - - 0.000000000000000000000000000000000000000000000001994 181.0
HFD2_k127_42824_14 - - - - 0.00000000000000006534 92.0
HFD2_k127_42824_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 573.0
HFD2_k127_42824_3 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 529.0
HFD2_k127_42824_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 499.0
HFD2_k127_42824_5 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 457.0
HFD2_k127_42824_6 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 428.0
HFD2_k127_42824_7 Transcriptional regulator, LysR family K21645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 426.0
HFD2_k127_42824_8 Belongs to the mandelate racemase muconate lactonizing enzyme family K22209 - 4.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 373.0
HFD2_k127_42824_9 Carboxyl transferase domain K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 349.0
HFD2_k127_4316784_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 3.234e-273 863.0
HFD2_k127_4316784_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 2.531e-212 665.0
HFD2_k127_4316784_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 384.0
HFD2_k127_4316784_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000189 117.0
HFD2_k127_4408591_0 helicase superfamily c-terminal domain K03724 - - 0.0 1220.0
HFD2_k127_4408591_1 heat shock protein binding - - - 1.851e-282 878.0
HFD2_k127_4408591_10 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 311.0
HFD2_k127_4408591_11 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009263 263.0
HFD2_k127_4408591_12 DoxX-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002777 265.0
HFD2_k127_4408591_13 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000001658 171.0
HFD2_k127_4408591_14 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000111 158.0
HFD2_k127_4408591_15 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000001378 156.0
HFD2_k127_4408591_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000006039 150.0
HFD2_k127_4408591_17 protein conserved in bacteria - - - 0.00000000000000004746 84.0
HFD2_k127_4408591_18 Protein of unknown function (DUF2917) - - - 0.000778 46.0
HFD2_k127_4408591_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.874e-245 765.0
HFD2_k127_4408591_3 ABC-type Fe3 transport system, permease component K02011 - - 3.937e-213 675.0
HFD2_k127_4408591_4 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 560.0
HFD2_k127_4408591_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 555.0
HFD2_k127_4408591_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 482.0
HFD2_k127_4408591_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 436.0
HFD2_k127_4408591_8 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 401.0
HFD2_k127_4408591_9 UTRA domain K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 340.0
HFD2_k127_4408600_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 2011.0
HFD2_k127_4408600_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 7.177e-256 794.0
HFD2_k127_4408600_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 4.283e-226 713.0
HFD2_k127_4408600_3 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 534.0
HFD2_k127_4408600_4 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000000000000000000001743 235.0
HFD2_k127_4408600_5 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000008766 175.0
HFD2_k127_4408600_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000001337 171.0
HFD2_k127_4408600_7 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000008615 159.0
HFD2_k127_4408600_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000005507 125.0
HFD2_k127_4408600_9 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.0000000000000000000000000001575 117.0
HFD2_k127_4437289_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0 1350.0
HFD2_k127_4437289_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 360.0
HFD2_k127_4437289_2 Feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001913 250.0
HFD2_k127_4437289_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006925 229.0
HFD2_k127_4437289_4 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000000007312 201.0
HFD2_k127_4437289_6 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000025 172.0
HFD2_k127_4437289_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0000000000000000000000000001508 130.0
HFD2_k127_4464924_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836,K07250 - 2.6.1.19,2.6.1.22,2.6.1.76 6.704e-230 717.0
HFD2_k127_4464924_1 Binding-protein-dependent transport system inner membrane component K02054 - - 3.131e-195 621.0
HFD2_k127_4464924_2 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 602.0
HFD2_k127_4464924_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 547.0
HFD2_k127_4464924_4 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 459.0
HFD2_k127_447568_0 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 1.781e-266 837.0
HFD2_k127_447568_1 Extracellular solute-binding protein K02027,K10227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 499.0
HFD2_k127_447568_2 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
HFD2_k127_447568_3 Domain of unknown function (DUF305) K08995 - - 0.00000000000000000000000000000000000000001026 171.0
HFD2_k127_447568_4 cheY-homologous receiver domain - - - 0.000000002792 70.0
HFD2_k127_4484961_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 390.0
HFD2_k127_4484961_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 364.0
HFD2_k127_4484961_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
HFD2_k127_4484961_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 322.0
HFD2_k127_4484961_4 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.00000000000000000000000000000000000000000000000002991 183.0
HFD2_k127_4484961_5 Bacterial transferase hexapeptide (six repeats) K13006,K19429 - - 0.0000000000000000000000000000000000000001032 159.0
HFD2_k127_4484961_6 Flagellar protein FliT K02423 - - 0.000000000000000000000000000000000000002813 150.0
HFD2_k127_4484961_7 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000000004204 160.0
HFD2_k127_4494595_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 294.0
HFD2_k127_4494595_1 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
HFD2_k127_4494595_2 Transcriptional - - - 0.0000000000000000000000000001294 119.0
HFD2_k127_4494595_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000002185 92.0
HFD2_k127_4494595_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000006126 85.0
HFD2_k127_4494595_5 PFAM regulatory protein, ArsR - - - 0.00000000241 59.0
HFD2_k127_4500193_0 Cytochrome C oxidase, cbb3-type, subunit III K18030 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 452.0
HFD2_k127_4500193_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
HFD2_k127_4500193_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 306.0
HFD2_k127_4500193_3 2Fe-2S -binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000189 229.0
HFD2_k127_4500193_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000008647 121.0
HFD2_k127_4516901_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.505e-314 973.0
HFD2_k127_4516901_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 565.0
HFD2_k127_4516901_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000007075 154.0
HFD2_k127_4516901_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000008055 155.0
HFD2_k127_4516901_2 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 478.0
HFD2_k127_4516901_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 409.0
HFD2_k127_4516901_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 356.0
HFD2_k127_4516901_5 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 319.0
HFD2_k127_4516901_6 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003193 241.0
HFD2_k127_4516901_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
HFD2_k127_4516901_8 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000000000000000000003884 231.0
HFD2_k127_4516901_9 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000006981 168.0
HFD2_k127_4517348_0 PFAM ATP-binding region, ATPase domain protein K11711 - 2.7.13.3 3.163e-266 842.0
HFD2_k127_4517348_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 567.0
HFD2_k127_4517348_10 prohibitin homologues - - - 0.00000000000000003562 92.0
HFD2_k127_4517348_2 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 537.0
HFD2_k127_4517348_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 475.0
HFD2_k127_4517348_4 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 401.0
HFD2_k127_4517348_5 helix_turn_helix, Lux Regulon K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 317.0
HFD2_k127_4517348_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
HFD2_k127_4517348_7 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
HFD2_k127_4517348_8 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000205 201.0
HFD2_k127_4517348_9 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000000000000000002758 201.0
HFD2_k127_4542227_0 Cytochrome P450 - - - 5.784e-198 627.0
HFD2_k127_4542227_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 559.0
HFD2_k127_4542227_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 439.0
HFD2_k127_4544853_0 response to copper ion - - - 0.00000000000000000000000000000000005993 145.0
HFD2_k127_4544853_1 Cell cycle protein - - - 0.000000000000000000000000000000001241 151.0
HFD2_k127_4544853_2 Phospholipid methyltransferase - - - 0.0000000000008017 68.0
HFD2_k127_4552757_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1086.0
HFD2_k127_4552757_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 1.226e-215 680.0
HFD2_k127_4552757_2 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 416.0
HFD2_k127_4552757_3 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 406.0
HFD2_k127_4552757_4 Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 392.0
HFD2_k127_4552757_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 322.0
HFD2_k127_4552757_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 335.0
HFD2_k127_4552757_7 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001699 231.0
HFD2_k127_4552757_8 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000000000000000000000003631 211.0
HFD2_k127_4552757_9 ProQ/FINO family K03607 - - 0.00000000000000000000000000000000000000000000000001003 199.0
HFD2_k127_4559137_0 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 418.0
HFD2_k127_4559137_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 434.0
HFD2_k127_4559137_2 - - - - 0.00000000000000000000000000000000000000000004254 173.0
HFD2_k127_4559137_3 Domain of unknown function (DUF4010) - - - 0.00000000000000006133 87.0
HFD2_k127_4573046_0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
HFD2_k127_4573046_1 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
HFD2_k127_4573046_2 SIR2-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 379.0
HFD2_k127_4573046_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 347.0
HFD2_k127_4573046_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 329.0
HFD2_k127_4573046_5 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000001932 166.0
HFD2_k127_4573046_6 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000002225 166.0
HFD2_k127_4573046_7 Putative regulatory protein - - - 0.00000000000000000000004124 101.0
HFD2_k127_4585274_0 general secretion pathway protein K02453 - - 2.685e-273 875.0
HFD2_k127_4585274_1 General secretion pathway K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 421.0
HFD2_k127_4585274_10 PFAM General secretion pathway, M protein K02462 - - 0.0000000000000000000000000000000000000005747 158.0
HFD2_k127_4585274_11 general secretion pathway protein K02452 - - 0.000000000000000000000000000000000062 152.0
HFD2_k127_4585274_2 Phosphoribosyltransferase K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 379.0
HFD2_k127_4585274_3 TIGRFAM general secretory pathway protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 328.0
HFD2_k127_4585274_4 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 341.0
HFD2_k127_4585274_5 Type II secretion system (T2SS), protein N K02463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 323.0
HFD2_k127_4585274_6 Prokaryotic N-terminal methylation motif K02459 - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 239.0
HFD2_k127_4585274_7 general secretion pathway protein K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000004264 240.0
HFD2_k127_4585274_8 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000000000000000000000005728 156.0
HFD2_k127_4585274_9 general secretion pathway protein K02458 - - 0.0000000000000000000000000000000000000004965 159.0
HFD2_k127_4595083_0 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 413.0
HFD2_k127_4595083_1 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 301.0
HFD2_k127_4595083_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005894 262.0
HFD2_k127_4595083_3 Sel1 repeat - - - 0.00000000000000000000000000000000000000004045 168.0
HFD2_k127_4600756_0 Diguanylate cyclase K21023 - 2.7.7.65 2.677e-252 798.0
HFD2_k127_4600756_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 529.0
HFD2_k127_4600756_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 430.0
HFD2_k127_4600756_3 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 335.0
HFD2_k127_4600756_4 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
HFD2_k127_4600756_5 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003719 255.0
HFD2_k127_4605814_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.912e-210 668.0
HFD2_k127_4605814_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 610.0
HFD2_k127_4605814_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HFD2_k127_4605814_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002695 250.0
HFD2_k127_4605814_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000007818 175.0
HFD2_k127_4605814_5 Cysteine-rich secretory protein family - - - 0.0000000002351 61.0
HFD2_k127_4616192_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 575.0
HFD2_k127_4616192_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 479.0
HFD2_k127_4616192_10 UTRA K05836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001307 246.0
HFD2_k127_4616192_11 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002602 263.0
HFD2_k127_4616192_12 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000001661 129.0
HFD2_k127_4616192_13 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000000000000000078 97.0
HFD2_k127_4616192_2 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 406.0
HFD2_k127_4616192_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 399.0
HFD2_k127_4616192_4 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 377.0
HFD2_k127_4616192_5 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 365.0
HFD2_k127_4616192_6 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HFD2_k127_4616192_7 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 333.0
HFD2_k127_4616192_8 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008546 264.0
HFD2_k127_4616192_9 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002674 258.0
HFD2_k127_4619376_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1914.0
HFD2_k127_4619376_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.987e-223 702.0
HFD2_k127_4619376_2 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 402.0
HFD2_k127_4619376_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 368.0
HFD2_k127_4619376_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 304.0
HFD2_k127_4619376_5 - - - - 0.000000000000000000000000000000000000000003646 164.0
HFD2_k127_4619376_6 - - - - 0.00000000000000000000003446 109.0
HFD2_k127_4619376_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000003073 106.0
HFD2_k127_4628959_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 2.504e-206 647.0
HFD2_k127_4628959_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 599.0
HFD2_k127_4628959_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 456.0
HFD2_k127_4628959_3 iron-nicotianamine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 407.0
HFD2_k127_4628959_4 Cell wall-associated K13695,K19303 - - 0.000000000000000000000000000000000000000000000000000000000000009427 222.0
HFD2_k127_4628959_5 FR47-like protein - - - 0.00000000000000000000000000000000000000001865 175.0
HFD2_k127_4628959_6 PFAM Alcohol dehydrogenase K19745 - - 0.000000003938 64.0
HFD2_k127_4637080_0 ribonuclease, Rne Rng family K08301 - - 1.701e-242 756.0
HFD2_k127_4637080_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004593 253.0
HFD2_k127_4637080_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000704 231.0
HFD2_k127_4637080_3 sugar ABC transporter substrate-binding protein K10439 - - 0.0000000000000000000000000007237 116.0
HFD2_k127_4645095_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0 1367.0
HFD2_k127_4645095_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.485e-242 767.0
HFD2_k127_4645095_10 binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 482.0
HFD2_k127_4645095_11 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 484.0
HFD2_k127_4645095_12 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 292.0
HFD2_k127_4645095_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 247.0
HFD2_k127_4645095_14 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006572 258.0
HFD2_k127_4645095_15 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000000000000001005 154.0
HFD2_k127_4645095_16 cellulose binding - - - 0.0000000000000000000000000000000966 125.0
HFD2_k127_4645095_17 domain, Protein - - - 0.000000000000000000000000001262 121.0
HFD2_k127_4645095_18 Oligopeptide dipeptide uptake family ABC transporter, ATP-binding protein K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000001007 95.0
HFD2_k127_4645095_19 - - - - 0.000000000000000000001285 99.0
HFD2_k127_4645095_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.529e-238 742.0
HFD2_k127_4645095_20 Domain of unknown function (DUF4212) - - - 0.00000000000000009679 86.0
HFD2_k127_4645095_21 PFAM transcriptional regulator domain protein - - - 0.00000000001183 78.0
HFD2_k127_4645095_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.036e-222 706.0
HFD2_k127_4645095_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.745e-202 631.0
HFD2_k127_4645095_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 623.0
HFD2_k127_4645095_6 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 601.0
HFD2_k127_4645095_7 Glycosyl hydrolase family 30 TIM-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 579.0
HFD2_k127_4645095_8 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 575.0
HFD2_k127_4645095_9 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 529.0
HFD2_k127_4651817_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1186.0
HFD2_k127_4651817_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 550.0
HFD2_k127_4651817_2 Peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 392.0
HFD2_k127_4651817_3 methyltransferase (Contains TPR repeat) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003039 255.0
HFD2_k127_4651817_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000006339 225.0
HFD2_k127_4651817_5 - - - - 0.00000000000000000000000000000000000000000000000000000001069 211.0
HFD2_k127_4651817_6 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000005559 158.0
HFD2_k127_4651817_7 bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000387 149.0
HFD2_k127_466206_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.805e-235 732.0
HFD2_k127_466206_1 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 431.0
HFD2_k127_466206_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 394.0
HFD2_k127_466206_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 406.0
HFD2_k127_466206_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 339.0
HFD2_k127_466206_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 319.0
HFD2_k127_4740839_0 FtsX-like permease family K02004 - - 0.0 1223.0
HFD2_k127_4740839_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739,K01740 - 2.5.1.48,2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 600.0
HFD2_k127_4740839_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 325.0
HFD2_k127_4740839_3 Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.000000000000000000000000000000000000000000000000001241 186.0
HFD2_k127_4740839_4 Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.00000000000000000000000000000000000002129 148.0
HFD2_k127_4783891_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 6.025e-209 654.0
HFD2_k127_4783891_1 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 505.0
HFD2_k127_4783891_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 331.0
HFD2_k127_4783891_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
HFD2_k127_4783891_4 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
HFD2_k127_4786512_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1140.0
HFD2_k127_4786512_1 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 4.123e-285 879.0
HFD2_k127_4786512_10 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 387.0
HFD2_k127_4786512_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 379.0
HFD2_k127_4786512_12 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 376.0
HFD2_k127_4786512_13 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 334.0
HFD2_k127_4786512_14 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 314.0
HFD2_k127_4786512_15 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 314.0
HFD2_k127_4786512_16 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 321.0
HFD2_k127_4786512_17 Bacteriocin-protection, YdeI or OmpD-Associated K06878 - - 0.00000000000000000000000000000000000000000000000000000005231 205.0
HFD2_k127_4786512_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000001317 157.0
HFD2_k127_4786512_19 Transglycosylase associated protein - - - 0.000000000000000000000000000000000002065 141.0
HFD2_k127_4786512_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 1.355e-227 711.0
HFD2_k127_4786512_20 - - - - 0.0000000000000000000000000000000001122 143.0
HFD2_k127_4786512_23 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000004927 92.0
HFD2_k127_4786512_24 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000009319 66.0
HFD2_k127_4786512_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.901e-210 693.0
HFD2_k127_4786512_4 PFAM cytochrome c class I K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 489.0
HFD2_k127_4786512_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 466.0
HFD2_k127_4786512_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 482.0
HFD2_k127_4786512_7 Transcriptional regulator, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 464.0
HFD2_k127_4786512_8 AAA domain K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 423.0
HFD2_k127_4786512_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 410.0
HFD2_k127_4794515_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1539.0
HFD2_k127_4794515_1 cytochrome C K02198 - - 5.714e-262 818.0
HFD2_k127_4794515_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000865 266.0
HFD2_k127_4794515_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000197 232.0
HFD2_k127_4794515_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000002641 228.0
HFD2_k127_4794515_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000003084 68.0
HFD2_k127_4794515_2 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 2.44e-242 754.0
HFD2_k127_4794515_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 8.116e-202 633.0
HFD2_k127_4794515_4 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 593.0
HFD2_k127_4794515_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 412.0
HFD2_k127_4794515_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 407.0
HFD2_k127_4794515_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
HFD2_k127_4794515_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 287.0
HFD2_k127_4794515_9 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004314 269.0
HFD2_k127_4812499_0 Ring hydroxylating alpha subunit (catalytic domain) K16319,K18242 - 1.14.12.1,1.14.13.172 3.507e-271 839.0
HFD2_k127_4812499_1 Oxidoreductase FAD-binding domain K00523,K14581 - 1.17.1.1,1.18.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 594.0
HFD2_k127_4812499_10 May be involved in recombination K03554 - - 0.0000000006251 62.0
HFD2_k127_4812499_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 531.0
HFD2_k127_4812499_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 517.0
HFD2_k127_4812499_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
HFD2_k127_4812499_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 355.0
HFD2_k127_4812499_6 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 304.0
HFD2_k127_4812499_7 SnoaL-like domain K16320,K18243 - 1.14.12.1,1.14.13.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 319.0
HFD2_k127_4812499_8 Rieske-like [2Fe-2S] domain K05710,K14578,K14750 - - 0.0000000000000000000000000000000000000000000000000008304 184.0
HFD2_k127_4812499_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000001183 115.0
HFD2_k127_4914461_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1785.0
HFD2_k127_4914461_1 HELICc2 K03722 - 3.6.4.12 9.969e-305 946.0
HFD2_k127_4914461_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 349.0
HFD2_k127_4914461_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 321.0
HFD2_k127_4914461_12 Protein of unknown function (DUF465) - - - 0.0000000000000000000005576 97.0
HFD2_k127_4914461_13 - - - - 0.0000008393 62.0
HFD2_k127_4914461_2 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 5.474e-270 836.0
HFD2_k127_4914461_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 4.043e-219 686.0
HFD2_k127_4914461_4 PFAM AFG1-family ATPase K06916 - - 1.507e-201 631.0
HFD2_k127_4914461_5 acyl-CoA dehydrogenase K20035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 597.0
HFD2_k127_4914461_6 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 529.0
HFD2_k127_4914461_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 517.0
HFD2_k127_4914461_8 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 434.0
HFD2_k127_4914461_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 422.0
HFD2_k127_492874_0 Histidine kinase K14986 - 2.7.13.3 0.0 1379.0
HFD2_k127_492874_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 575.0
HFD2_k127_492874_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 320.0
HFD2_k127_492874_3 Histidine kinase - - - 0.00005725 48.0
HFD2_k127_4941236_0 Sulphur transport K07112,K19168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 344.0
HFD2_k127_4941236_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 305.0
HFD2_k127_4941236_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000003204 221.0
HFD2_k127_4941236_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000996 220.0
HFD2_k127_4943719_0 ABC transporter K06158 - - 3.644e-232 725.0
HFD2_k127_4943719_1 Aminotransferase K14267 - 2.6.1.17 6.28e-204 655.0
HFD2_k127_4943719_2 twitching motility protein K02670 - - 1.113e-196 619.0
HFD2_k127_4943719_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 580.0
HFD2_k127_4943719_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 476.0
HFD2_k127_4943719_5 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 415.0
HFD2_k127_4943719_6 LysM domain - - - 0.0000000000000000000000000000000000000000000000000003594 212.0
HFD2_k127_4943719_7 CpXC protein - - - 0.0000000000000000000000000000000000000000000000004666 187.0
HFD2_k127_4962509_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.161e-216 679.0
HFD2_k127_4962509_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.816e-204 637.0
HFD2_k127_4962509_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 538.0
HFD2_k127_4962509_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
HFD2_k127_4962509_4 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 309.0
HFD2_k127_4962509_5 - - - - 0.0000000000000000000002319 97.0
HFD2_k127_4988529_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.248e-206 661.0
HFD2_k127_4988529_1 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 394.0
HFD2_k127_4988529_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 391.0
HFD2_k127_4988529_3 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 403.0
HFD2_k127_4988529_4 5-oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000145 217.0
HFD2_k127_4988529_5 Tripartite ATP-independent periplasmic transporter subunit DctQ family protein 5 - - - 0.000000000000000000000000000003241 137.0
HFD2_k127_5009041_0 Likely ribonuclease with RNase H fold. K06959 - - 0.0 1204.0
HFD2_k127_5009041_1 Acetyl-CoA dehydrogenase C-terminal like K00248 - 1.3.8.1 4.925e-315 974.0
HFD2_k127_5009041_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 331.0
HFD2_k127_5009041_11 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000005039 187.0
HFD2_k127_5009041_12 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000804 200.0
HFD2_k127_5009041_13 - - - - 0.00000443 59.0
HFD2_k127_5009041_2 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 7.835e-250 781.0
HFD2_k127_5009041_3 Peptidase family M3 K01392 - 3.4.24.15 1.114e-249 787.0
HFD2_k127_5009041_4 Belongs to the thiolase family K00626 - 2.3.1.9 7.399e-223 699.0
HFD2_k127_5009041_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 550.0
HFD2_k127_5009041_6 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 563.0
HFD2_k127_5009041_7 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 440.0
HFD2_k127_5009041_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 464.0
HFD2_k127_5009041_9 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 417.0
HFD2_k127_5071235_0 - - - - 3.932e-233 747.0
HFD2_k127_5071235_1 Glutamate decarboxylase and related PLP-dependent K01580 - 4.1.1.15 9.53e-197 625.0
HFD2_k127_5071235_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 532.0
HFD2_k127_5071235_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 492.0
HFD2_k127_5071235_4 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 362.0
HFD2_k127_5071235_5 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 326.0
HFD2_k127_5071235_6 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000001161 197.0
HFD2_k127_5071235_7 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 0.00000000000000000000000000000000000000000000001925 174.0
HFD2_k127_5082366_0 Tripartite tricarboxylate transporter TctA family - - - 2.817e-271 840.0
HFD2_k127_5082366_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.847e-251 784.0
HFD2_k127_5082366_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000007328 144.0
HFD2_k127_5082366_12 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000006263 148.0
HFD2_k127_5082366_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000003487 151.0
HFD2_k127_5082366_14 AntiSigma factor - - - 0.000000000000000000000000000000002372 146.0
HFD2_k127_5082366_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000147 121.0
HFD2_k127_5082366_16 helix_turn_helix, Lux Regulon - - - 0.0000000000000000001453 101.0
HFD2_k127_5082366_17 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000003295 93.0
HFD2_k127_5082366_2 Major Facilitator Superfamily - - - 7.681e-222 696.0
HFD2_k127_5082366_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
HFD2_k127_5082366_4 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
HFD2_k127_5082366_5 polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000007471 228.0
HFD2_k127_5082366_6 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000002076 200.0
HFD2_k127_5082366_7 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000001389 194.0
HFD2_k127_5082366_8 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000009014 190.0
HFD2_k127_5082366_9 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000001752 186.0
HFD2_k127_5093483_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 452.0
HFD2_k127_5093483_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 340.0
HFD2_k127_5093483_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001025 269.0
HFD2_k127_5093483_3 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002239 254.0
HFD2_k127_5093483_4 PFAM porin Gram-negative type - - - 0.0000000000000000000000000000000000000009796 162.0
HFD2_k127_5093483_5 Periplasmic Protein - - - 0.000000000000000000000000000000000003317 146.0
HFD2_k127_5093483_6 tryptophan synthase subunit beta - - - 0.0000000000000000000000000006039 121.0
HFD2_k127_5093483_7 Adenylate cyclase - - - 0.0000000000000000000000165 102.0
HFD2_k127_509373_0 ABC transporter K06020 - 3.6.3.25 8.019e-318 979.0
HFD2_k127_509373_1 Domain of unknown function (DUF5117) - - - 4.338e-285 903.0
HFD2_k127_509373_10 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 372.0
HFD2_k127_509373_11 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
HFD2_k127_509373_12 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002838 297.0
HFD2_k127_509373_13 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 245.0
HFD2_k127_509373_14 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000001731 222.0
HFD2_k127_509373_15 Pfam Response regulator receiver K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000001972 222.0
HFD2_k127_509373_16 - - - - 0.00000000000000000000000000000000636 142.0
HFD2_k127_509373_17 - - - - 0.000000000000009148 87.0
HFD2_k127_509373_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 2.069e-276 885.0
HFD2_k127_509373_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 7.571e-214 697.0
HFD2_k127_509373_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 612.0
HFD2_k127_509373_5 RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 600.0
HFD2_k127_509373_6 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 569.0
HFD2_k127_509373_7 Histidine kinase K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 527.0
HFD2_k127_509373_8 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 482.0
HFD2_k127_509373_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 467.0
HFD2_k127_5139496_0 Murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 593.0
HFD2_k127_5139496_1 Protein of unknown function (DUF4243) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001676 292.0
HFD2_k127_5139496_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008029 262.0
HFD2_k127_5139496_3 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000002731 179.0
HFD2_k127_5139496_4 TonB C terminal - - - 0.000000000000000000000000000000000000000005868 157.0
HFD2_k127_5139496_5 - - - - 0.0000000000000000000000000002009 126.0
HFD2_k127_5139496_6 - - - - 0.0000000000000000000000002057 112.0
HFD2_k127_5139496_7 - - - - 0.000000000000004507 86.0
HFD2_k127_5150278_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.614e-256 799.0
HFD2_k127_5150278_1 ABC-type dipeptide transport system, periplasmic component - - - 2.134e-237 752.0
HFD2_k127_5150278_2 ABC-type dipeptide transport system, periplasmic component - - - 2.661e-229 744.0
HFD2_k127_5150278_3 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 322.0
HFD2_k127_5200287_0 Histidine kinase-like ATPases - - - 6.257e-195 623.0
HFD2_k127_5200287_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 355.0
HFD2_k127_5200287_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 308.0
HFD2_k127_5200287_3 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000005375 202.0
HFD2_k127_5200287_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000002001 151.0
HFD2_k127_522888_0 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 299.0
HFD2_k127_522888_1 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000559 267.0
HFD2_k127_522888_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000007546 187.0
HFD2_k127_522888_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000005219 138.0
HFD2_k127_522888_4 OmpA family - - - 0.00000000000000000000000000000000009417 143.0
HFD2_k127_526916_0 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 492.0
HFD2_k127_526916_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 488.0
HFD2_k127_526916_10 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000009615 226.0
HFD2_k127_526916_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000001471 65.0
HFD2_k127_526916_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 420.0
HFD2_k127_526916_3 Aldo/keto reductase family K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 368.0
HFD2_k127_526916_4 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 337.0
HFD2_k127_526916_5 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 330.0
HFD2_k127_526916_6 4-Hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 286.0
HFD2_k127_526916_7 PFAM regulatory protein AsnC Lrp family K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000869 262.0
HFD2_k127_526916_8 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001783 274.0
HFD2_k127_526916_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000001807 239.0
HFD2_k127_5283110_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 509.0
HFD2_k127_5283110_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
HFD2_k127_5283110_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009573 251.0
HFD2_k127_5283110_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000001887 188.0
HFD2_k127_5329413_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 6.929e-221 686.0
HFD2_k127_5329413_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 588.0
HFD2_k127_5329413_2 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 469.0
HFD2_k127_5329413_3 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 415.0
HFD2_k127_5329413_4 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 358.0
HFD2_k127_5329413_5 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000000000000000000000000005637 235.0
HFD2_k127_5329413_6 Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000000000000007125 155.0
HFD2_k127_5329413_7 Universal stress protein - - - 0.000000000000000000000000000000000008915 141.0
HFD2_k127_5329413_8 ferredoxin-type protein napF K02572 - - 0.00000000000000000768 89.0
HFD2_k127_5347357_0 NMT1-like family K15553 - - 8.425e-224 707.0
HFD2_k127_5347357_1 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 406.0
HFD2_k127_5347357_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 411.0
HFD2_k127_5347357_3 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 365.0
HFD2_k127_5347357_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HFD2_k127_5347357_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000009094 189.0
HFD2_k127_5347357_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000001345 110.0
HFD2_k127_5347357_7 Protein of unknown function (DUF971) - - - 0.0000000000000047 87.0
HFD2_k127_5355957_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 6.43e-237 745.0
HFD2_k127_5355957_1 Involved in the TonB-independent uptake of proteins K03641 - - 5.845e-201 637.0
HFD2_k127_5355957_10 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0002643 43.0
HFD2_k127_5355957_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 488.0
HFD2_k127_5355957_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 423.0
HFD2_k127_5355957_4 ThiF family K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 343.0
HFD2_k127_5355957_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 316.0
HFD2_k127_5355957_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 326.0
HFD2_k127_5355957_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HFD2_k127_5355957_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000001345 283.0
HFD2_k127_5355957_9 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000001913 197.0
HFD2_k127_5362011_0 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 507.0
HFD2_k127_5362011_1 flagellar basal-body rod protein K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 413.0
HFD2_k127_5362011_2 Flagellar basal-body rod protein FlgF K02391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 358.0
HFD2_k127_5362011_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002644 289.0
HFD2_k127_5362011_4 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HFD2_k127_5362011_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000003436 132.0
HFD2_k127_5362295_0 PFAM glycoside hydrolase, family 10 - - - 2.627e-262 831.0
HFD2_k127_5362295_1 UDP binding domain K02474 - - 2.485e-230 717.0
HFD2_k127_5362295_10 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 414.0
HFD2_k127_5362295_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 379.0
HFD2_k127_5362295_12 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 363.0
HFD2_k127_5362295_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 344.0
HFD2_k127_5362295_14 Belongs to the glycosyltransferase 26 family K05946,K13660 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
HFD2_k127_5362295_15 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 303.0
HFD2_k127_5362295_16 Polysaccharide biosynthesis protein K03328,K16694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 299.0
HFD2_k127_5362295_17 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008657 287.0
HFD2_k127_5362295_18 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009352 274.0
HFD2_k127_5362295_19 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000001024 239.0
HFD2_k127_5362295_2 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 1.548e-227 711.0
HFD2_k127_5362295_20 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000001601 236.0
HFD2_k127_5362295_21 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000000000000000000001706 183.0
HFD2_k127_5362295_22 Acyltransferase family - - - 0.000000000000000000000000000000000000000000005236 177.0
HFD2_k127_5362295_23 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000001745 157.0
HFD2_k127_5362295_24 Cytochrome c K08738 - - 0.00000000000000000006164 98.0
HFD2_k127_5362295_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 4.528e-217 689.0
HFD2_k127_5362295_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 7.813e-204 652.0
HFD2_k127_5362295_5 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 572.0
HFD2_k127_5362295_6 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 500.0
HFD2_k127_5362295_7 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 491.0
HFD2_k127_5362295_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 468.0
HFD2_k127_5362295_9 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 442.0
HFD2_k127_5383497_0 PFAM ABC transporter related K10441 - 3.6.3.17 1.314e-236 744.0
HFD2_k127_5383497_1 Periplasmic binding protein domain K10439 - - 7.567e-200 626.0
HFD2_k127_5383497_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 581.0
HFD2_k127_5383497_3 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 323.0
HFD2_k127_5383497_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 255.0
HFD2_k127_5383497_5 chlorophyll binding - - - 0.000000000000000000000000000009549 133.0
HFD2_k127_5395212_0 Lytic transglycosylase catalytic K08309 - - 1.576e-264 833.0
HFD2_k127_5395212_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
HFD2_k127_5395212_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000003781 194.0
HFD2_k127_5395212_3 Transcriptional regulator K03566 - - 0.0000000000003062 70.0
HFD2_k127_5395212_4 signal transduction histidine kinase K07678 - 2.7.13.3 0.0001233 46.0
HFD2_k127_5448743_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 4.826e-296 940.0
HFD2_k127_5448743_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 1.785e-261 818.0
HFD2_k127_5448743_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000407 145.0
HFD2_k127_5448743_11 phosphorelay signal transduction system - - - 0.0000000000000000000000002084 114.0
HFD2_k127_5448743_12 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000006623 106.0
HFD2_k127_5448743_13 Universal stress protein family - - - 0.00000000000000000000001926 100.0
HFD2_k127_5448743_14 Matrix metallopeptidase 12 K01388,K01394,K01396,K01402,K01413,K07763,K07994,K07999 GO:0000122,GO:0001047,GO:0001067,GO:0001666,GO:0001817,GO:0001819,GO:0001959,GO:0001960,GO:0001961,GO:0002009,GO:0002011,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002791,GO:0002793,GO:0002831,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005509,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0006508,GO:0006606,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006928,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008284,GO:0009056,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009628,GO:0009653,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0014070,GO:0015031,GO:0015833,GO:0016043,GO:0016477,GO:0016787,GO:0017038,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0022411,GO:0022617,GO:0023051,GO:0023056,GO:0023057,GO:0030198,GO:0030334,GO:0030574,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031349,GO:0032101,GO:0032479,GO:0032481,GO:0032502,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0032963,GO:0033036,GO:0033365,GO:0034504,GO:0034613,GO:0035313,GO:0036293,GO:0040011,GO:0040012,GO:0042060,GO:0042127,GO:0042221,GO:0042493,GO:0042886,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043900,GO:0044212,GO:0044238,GO:0044319,GO:0044421,GO:0044424,GO:0044464,GO:0044877,GO:0045088,GO:0045089,GO:0045184,GO:0045824,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046872,GO:0046907,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048729,GO:0048856,GO:0048870,GO:0050678,GO:0050679,GO:0050688,GO:0050691,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0060054,GO:0060255,GO:0060338,GO:0060339,GO:0060340,GO:0060429,GO:0060759,GO:0060760,GO:0060761,GO:0065007,GO:0070011,GO:0070201,GO:0070482,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0080134,GO:0090087,GO:0090504,GO:0090505,GO:0097159,GO:0098586,GO:0140096,GO:1901163,GO:1901363,GO:1901564,GO:1902679,GO:1902680,GO:1902739,GO:1902741,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903532,GO:1904951,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000241,GO:2001141 3.4.24.17,3.4.24.22,3.4.24.34,3.4.24.65,3.4.24.7,3.4.24.80 0.00000000191 70.0
HFD2_k127_5448743_15 - - - - 0.0001007 50.0
HFD2_k127_5448743_2 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 530.0
HFD2_k127_5448743_3 coenzyme F390 synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 519.0
HFD2_k127_5448743_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 478.0
HFD2_k127_5448743_5 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 314.0
HFD2_k127_5448743_6 histidine kinase dimerisation and phosphoacceptor region K02486 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 327.0
HFD2_k127_5448743_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 295.0
HFD2_k127_5448743_8 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 294.0
HFD2_k127_5448743_9 regulatory protein Crp K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 260.0
HFD2_k127_5467536_0 MMPL family K07003 - - 0.0 1189.0
HFD2_k127_5467536_1 Histidine kinase-like ATPases - - - 1.159e-264 835.0
HFD2_k127_5467536_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 396.0
HFD2_k127_5467536_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 400.0
HFD2_k127_5467536_12 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 379.0
HFD2_k127_5467536_13 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 368.0
HFD2_k127_5467536_14 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 366.0
HFD2_k127_5467536_15 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 341.0
HFD2_k127_5467536_16 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 323.0
HFD2_k127_5467536_17 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 329.0
HFD2_k127_5467536_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
HFD2_k127_5467536_19 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000002979 199.0
HFD2_k127_5467536_2 Protein of unknown function (DUF1329) - - - 2.926e-219 688.0
HFD2_k127_5467536_3 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 2.512e-203 643.0
HFD2_k127_5467536_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 534.0
HFD2_k127_5467536_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 513.0
HFD2_k127_5467536_6 RNA polymerase sigma K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 442.0
HFD2_k127_5467536_7 Alpha beta hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 413.0
HFD2_k127_5467536_8 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 404.0
HFD2_k127_5467536_9 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 409.0
HFD2_k127_5501191_0 Sugar (and other) transporter - - - 2.342e-249 779.0
HFD2_k127_5501191_1 PFAM oxidoreductase domain protein K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 504.0
HFD2_k127_5501191_2 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 480.0
HFD2_k127_5501191_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 444.0
HFD2_k127_5501191_4 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 436.0
HFD2_k127_5501191_5 Transcriptional regulator IclR K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 323.0
HFD2_k127_5501191_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 334.0
HFD2_k127_5501191_7 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002994 301.0
HFD2_k127_5501191_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
HFD2_k127_5509771_0 Belongs to the thiolase family K00626 - 2.3.1.9 8.44e-201 646.0
HFD2_k127_5509771_1 Belongs to the 5'-nucleotidase family K01081,K17224 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 524.0
HFD2_k127_5509771_2 Formate/nitrite transporter K02598,K06212 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
HFD2_k127_5509771_3 - - - - 0.0000000000002325 72.0
HFD2_k127_5525756_0 RNA-metabolising metallo-beta-lactamase K07576 - - 2.434e-216 691.0
HFD2_k127_5525756_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 469.0
HFD2_k127_5525756_2 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 421.0
HFD2_k127_5525756_3 Transcriptional regulatory protein, C terminal K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 335.0
HFD2_k127_5525756_4 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
HFD2_k127_5525756_5 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000002013 224.0
HFD2_k127_5525756_6 LTXXQ motif family protein - - - 0.000000000000000000000000000000000002265 153.0
HFD2_k127_5532686_0 Transporter - - - 8.893e-306 945.0
HFD2_k127_5532686_1 Outer membrane protein beta-barrel family - - - 3.221e-259 826.0
HFD2_k127_5532686_2 DNA polymerase III K02342 - 2.7.7.7 1.731e-228 717.0
HFD2_k127_5532686_3 Hpt domain - - - 5.329e-217 725.0
HFD2_k127_5532686_4 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 477.0
HFD2_k127_5532686_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 376.0
HFD2_k127_5532686_6 PFAM AMP-dependent synthetase and ligase K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 301.0
HFD2_k127_5532686_7 - - - - 0.0000000000000000000000000000000000000000000000000000004627 197.0
HFD2_k127_5532686_8 Cysteine-rich CWC - - - 0.000000000004278 76.0
HFD2_k127_5535115_0 Protein of unknown function (DUF1800) - - - 7.737e-207 657.0
HFD2_k127_5535115_1 Tat pathway signal - - - 3.703e-203 645.0
HFD2_k127_5535115_2 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 521.0
HFD2_k127_5535115_3 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 493.0
HFD2_k127_5535115_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 435.0
HFD2_k127_5535115_5 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 346.0
HFD2_k127_5535115_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 297.0
HFD2_k127_5535115_7 PFAM TatD-related deoxyribonuclease K03424 - - 0.0003543 54.0
HFD2_k127_5553052_0 Histidinol phosphatase and related hydrolases of the PHP family - - - 0.0 1099.0
HFD2_k127_5553052_1 Spermidine synthase K00797 - 2.5.1.16 5.178e-302 950.0
HFD2_k127_5553052_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 497.0
HFD2_k127_5553052_3 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 439.0
HFD2_k127_5553052_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 360.0
HFD2_k127_5553052_5 Mg2 transporter protein cora family protein K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 360.0
HFD2_k127_556568_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1123.0
HFD2_k127_556568_1 Pyridine nucleotide-disulphide oxidoreductase - - - 1.248e-214 674.0
HFD2_k127_556568_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 539.0
HFD2_k127_556568_3 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HFD2_k127_556568_4 Putative heavy-metal chelation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008816 277.0
HFD2_k127_556568_5 Ribbon-helix-helix domain - - - 0.0000000000000000000000000000000000000000000000000000004501 207.0
HFD2_k127_556568_6 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000000000001657 134.0
HFD2_k127_556568_7 Mut7-C ubiquitin - - - 0.00000000000000000000000004721 124.0
HFD2_k127_556568_8 - - - - 0.000000000000000000000004371 109.0
HFD2_k127_557860_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1060.0
HFD2_k127_557860_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 1.162e-206 647.0
HFD2_k127_557860_11 acid phosphatase activity K01727 - 4.2.2.1 0.0000000000000000001039 102.0
HFD2_k127_557860_13 Protein of unknown function, DUF484 K09921 - - 0.00006061 55.0
HFD2_k127_557860_2 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 448.0
HFD2_k127_557860_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 446.0
HFD2_k127_557860_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 381.0
HFD2_k127_557860_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 394.0
HFD2_k127_557860_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 361.0
HFD2_k127_557860_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 317.0
HFD2_k127_557860_8 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000502 248.0
HFD2_k127_557860_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002134 142.0
HFD2_k127_5582271_0 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 348.0
HFD2_k127_5582271_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 295.0
HFD2_k127_5582271_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003116 241.0
HFD2_k127_5582271_3 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000000000000000001996 233.0
HFD2_k127_5582271_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000296 213.0
HFD2_k127_5582271_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000004271 181.0
HFD2_k127_5582271_6 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000206 144.0
HFD2_k127_5596468_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 9.414e-227 704.0
HFD2_k127_5596468_1 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
HFD2_k127_560982_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.381e-304 946.0
HFD2_k127_560982_1 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 2.881e-203 636.0
HFD2_k127_560982_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 502.0
HFD2_k127_560982_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 452.0
HFD2_k127_560982_4 Protein conserved in bacteria K09924 - - 0.0000000000000000000000000000000000001795 146.0
HFD2_k127_5642803_0 CBS domain containing protein K03699 - - 3.157e-208 655.0
HFD2_k127_5642803_1 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 437.0
HFD2_k127_5642803_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 412.0
HFD2_k127_5642803_3 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002176 273.0
HFD2_k127_5642803_4 SapC - - - 0.000000000000000000000000000000000000000000000001005 187.0
HFD2_k127_5642803_5 - - - - 0.000000000003697 68.0
HFD2_k127_5642803_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000776 55.0
HFD2_k127_5647694_0 Pilus formation protein N terminal region K02280 - - 3.356e-203 664.0
HFD2_k127_5647694_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 557.0
HFD2_k127_5647694_10 PFAM Flp Fap pilin component K02651 - - 0.00000000000001494 75.0
HFD2_k127_5647694_11 - - - - 0.0000000009533 63.0
HFD2_k127_5647694_12 Flp Fap pilin component K02651 - - 0.00000001873 62.0
HFD2_k127_5647694_2 AAA ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 483.0
HFD2_k127_5647694_3 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 336.0
HFD2_k127_5647694_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000008314 217.0
HFD2_k127_5647694_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000006792 207.0
HFD2_k127_5647694_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001873 200.0
HFD2_k127_5647694_7 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000000000000000000000002403 128.0
HFD2_k127_5647694_8 cheY-homologous receiver domain - - - 0.00000000000000000003803 99.0
HFD2_k127_5647694_9 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000004982 93.0
HFD2_k127_5661267_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.583e-239 747.0
HFD2_k127_5661267_1 May be involved in recombinational repair of damaged DNA K03631 - - 4.458e-230 724.0
HFD2_k127_5661267_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 558.0
HFD2_k127_5661267_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 434.0
HFD2_k127_5661267_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 424.0
HFD2_k127_5661267_5 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 299.0
HFD2_k127_5661267_6 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006602 280.0
HFD2_k127_5661267_7 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001256 254.0
HFD2_k127_5661267_8 nUDIX hydrolase - - - 0.00000000000000000000000000000000000002057 147.0
HFD2_k127_5661267_9 DeoR C terminal sensor domain K02081 - - 0.000000000000000000000000000000000005319 140.0
HFD2_k127_5669998_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 8.245e-310 952.0
HFD2_k127_5669998_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 505.0
HFD2_k127_5669998_2 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 477.0
HFD2_k127_5669998_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 385.0
HFD2_k127_5669998_4 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 322.0
HFD2_k127_5669998_5 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002844 263.0
HFD2_k127_5669998_6 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000189 181.0
HFD2_k127_5669998_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00001248 50.0
HFD2_k127_5682660_0 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 590.0
HFD2_k127_5682660_1 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 552.0
HFD2_k127_5682660_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 494.0
HFD2_k127_5682660_3 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 445.0
HFD2_k127_5682660_4 PFAM PEBP family protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001175 247.0
HFD2_k127_5682660_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000009577 212.0
HFD2_k127_5709972_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1026.0
HFD2_k127_5709972_1 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 384.0
HFD2_k127_5709972_2 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 350.0
HFD2_k127_5709972_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000000000000000003695 190.0
HFD2_k127_5709972_4 - - - - 0.00000000000000000004431 94.0
HFD2_k127_5709972_5 - - - - 0.0000000000000000002976 94.0
HFD2_k127_5716305_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5e-324 1009.0
HFD2_k127_5716305_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 5.728e-264 834.0
HFD2_k127_5716305_10 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000009422 249.0
HFD2_k127_5716305_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
HFD2_k127_5716305_12 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000001403 182.0
HFD2_k127_5716305_13 fmn reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000006585 183.0
HFD2_k127_5716305_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 505.0
HFD2_k127_5716305_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 436.0
HFD2_k127_5716305_4 TIGRFAM aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 428.0
HFD2_k127_5716305_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 387.0
HFD2_k127_5716305_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 370.0
HFD2_k127_5716305_7 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
HFD2_k127_5716305_8 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 327.0
HFD2_k127_5716305_9 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000003865 276.0
HFD2_k127_5727656_0 Large family of predicted nucleotide-binding domains K07175 - - 2.201e-287 889.0
HFD2_k127_5727656_1 PFAM aminotransferase, class I and II K14260 - 2.6.1.2,2.6.1.66 2.318e-242 753.0
HFD2_k127_5727656_2 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 495.0
HFD2_k127_5727656_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 512.0
HFD2_k127_5727656_4 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 320.0
HFD2_k127_5727656_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 295.0
HFD2_k127_5727656_6 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000006704 151.0
HFD2_k127_5729387_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 485.0
HFD2_k127_5729387_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 386.0
HFD2_k127_5729387_2 urea ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 295.0
HFD2_k127_5729387_3 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
HFD2_k127_5729387_4 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001084 271.0
HFD2_k127_5729387_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004175 257.0
HFD2_k127_5729387_6 leucine binding - - - 0.0000000000000000000000000000000000000000000005003 182.0
HFD2_k127_5753076_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 591.0
HFD2_k127_5753076_1 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 574.0
HFD2_k127_5753076_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 334.0
HFD2_k127_5753076_3 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 256.0
HFD2_k127_5753076_4 Alpha amylase, catalytic domain K01187,K01208,K21575 - 3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000001 248.0
HFD2_k127_5753076_5 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000004984 214.0
HFD2_k127_5753076_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001974 171.0
HFD2_k127_5753076_7 Protein of unknown function (DUF1255) - - - 0.000000000000000000000000000000000000000001033 158.0
HFD2_k127_5806508_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.425e-255 790.0
HFD2_k127_5806508_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 6.519e-215 676.0
HFD2_k127_5806508_2 Regulator K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006387 276.0
HFD2_k127_5806508_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000004706 192.0
HFD2_k127_5806508_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000007718 195.0
HFD2_k127_5806508_5 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000437 127.0
HFD2_k127_5806508_6 Belongs to the ClpA ClpB family K03694 - - 0.00000000000006455 73.0
HFD2_k127_5829950_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 7.171e-268 845.0
HFD2_k127_5829950_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.416e-231 727.0
HFD2_k127_5829950_10 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 378.0
HFD2_k127_5829950_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 352.0
HFD2_k127_5829950_12 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 329.0
HFD2_k127_5829950_13 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000008552 281.0
HFD2_k127_5829950_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.29e-228 741.0
HFD2_k127_5829950_3 outer membrane cobalamin receptor K02014,K16092 - - 3.204e-200 640.0
HFD2_k127_5829950_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 543.0
HFD2_k127_5829950_5 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 510.0
HFD2_k127_5829950_6 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 506.0
HFD2_k127_5829950_7 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 503.0
HFD2_k127_5829950_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 469.0
HFD2_k127_5829950_9 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 453.0
HFD2_k127_5839832_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.195e-242 753.0
HFD2_k127_5839832_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.013e-237 766.0
HFD2_k127_5839832_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 4.552e-234 762.0
HFD2_k127_5839832_3 ABC transporter K02056 - 3.6.3.17 7.328e-217 688.0
HFD2_k127_5839832_4 basic membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 543.0
HFD2_k127_5839832_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 505.0
HFD2_k127_5839832_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 501.0
HFD2_k127_5839832_7 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 424.0
HFD2_k127_5839832_8 - - - - 0.000000000000000000000000000000006376 130.0
HFD2_k127_5839832_9 Pyrimidine nucleoside phosphorylase C-terminal domain K00758 - 2.4.2.4 0.00000000000000000006474 93.0
HFD2_k127_5846140_0 MreB/Mbl protein K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 593.0
HFD2_k127_5846140_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 537.0
HFD2_k127_5846140_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000003093 202.0
HFD2_k127_5846140_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000005532 169.0
HFD2_k127_5846140_4 COG0457 FOG TPR repeat - - - 0.00000000000000000000001926 100.0
HFD2_k127_5846140_5 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000003002 100.0
HFD2_k127_5846140_6 COG0457 FOG TPR repeat - - - 0.000000000005243 72.0
HFD2_k127_5874793_0 Bacterial extracellular solute-binding protein K02055 - - 5.317e-250 795.0
HFD2_k127_5874793_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 554.0
HFD2_k127_5874793_2 TOBE domain K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 549.0
HFD2_k127_5874793_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 502.0
HFD2_k127_5874793_4 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008302 489.0
HFD2_k127_5874793_5 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 318.0
HFD2_k127_5874793_6 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 295.0
HFD2_k127_5874793_7 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 303.0
HFD2_k127_5874793_8 Transcription regulator MerR DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000002068 205.0
HFD2_k127_5882705_0 Exonuclease C-terminal K01141 - 3.1.11.1 2.367e-230 721.0
HFD2_k127_5882705_1 - - - - 0.000000000000000000000001212 106.0
HFD2_k127_5882705_2 Metallo-beta-lactamase superfamily - - - 0.00000000001283 68.0
HFD2_k127_5882705_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000004449 60.0
HFD2_k127_5908085_0 type VI secretion protein - - - 0.0 1240.0
HFD2_k127_5908085_1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 537.0
HFD2_k127_5908085_2 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 395.0
HFD2_k127_5908085_3 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 376.0
HFD2_k127_5908085_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 308.0
HFD2_k127_5908085_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007294 256.0
HFD2_k127_5908085_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001069 248.0
HFD2_k127_5908085_7 - - - - 0.0000000000000000009908 90.0
HFD2_k127_5908085_8 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000004794 68.0
HFD2_k127_5908085_9 - - - - 0.00000000008687 68.0
HFD2_k127_590844_0 PFAM Phospholipase D Transphosphatidylase K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 557.0
HFD2_k127_590844_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 418.0
HFD2_k127_590844_2 Pterin binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 369.0
HFD2_k127_590844_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 335.0
HFD2_k127_590844_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009364 257.0
HFD2_k127_590844_5 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000006667 124.0
HFD2_k127_590844_6 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.00000000000000000000000008358 110.0
HFD2_k127_5963751_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1028.0
HFD2_k127_5963751_1 Cation transport ATPase (P-type) K01537 - 3.6.3.8 8.83e-285 900.0
HFD2_k127_5963751_10 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 481.0
HFD2_k127_5963751_11 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 396.0
HFD2_k127_5963751_12 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 359.0
HFD2_k127_5963751_13 Autoinducer binding domain K07782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000924 276.0
HFD2_k127_5963751_14 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
HFD2_k127_5963751_15 - - - - 0.00000000000000000000000000000000000002586 153.0
HFD2_k127_5963751_16 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000007941 159.0
HFD2_k127_5963751_17 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000276 133.0
HFD2_k127_5963751_18 - - - - 0.0000000004214 66.0
HFD2_k127_5963751_2 Patatin-like phospholipase - - - 1.353e-259 837.0
HFD2_k127_5963751_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.407e-223 709.0
HFD2_k127_5963751_4 phosphate-selective porin O and P - - - 2.995e-203 645.0
HFD2_k127_5963751_5 belongs to the aldehyde dehydrogenase family K00151,K10217 - 1.2.1.32,1.2.1.60,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 535.0
HFD2_k127_5963751_6 3,4-dihydroxyphenylacetate 2,3-dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 530.0
HFD2_k127_5963751_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 503.0
HFD2_k127_5963751_8 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 503.0
HFD2_k127_5963751_9 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 506.0
HFD2_k127_596804_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.181e-295 920.0
HFD2_k127_596804_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.022e-287 889.0
HFD2_k127_596804_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 580.0
HFD2_k127_596804_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
HFD2_k127_596804_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 347.0
HFD2_k127_596804_5 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
HFD2_k127_596804_6 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000000005427 175.0
HFD2_k127_596804_7 Alanine racemase, N-terminal domain - - - 0.000000000000000000000000000000001089 132.0
HFD2_k127_596804_8 Transcriptional regulatory protein, C terminal K07663 - - 0.00000000000000000000000000000001954 141.0
HFD2_k127_5969638_0 PFAM aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 439.0
HFD2_k127_5969638_1 Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 398.0
HFD2_k127_5969638_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000135 240.0
HFD2_k127_5969638_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000002182 171.0
HFD2_k127_5969638_4 YCII-related domain - - - 0.00000000000000000000000001275 116.0
HFD2_k127_5969638_5 bacterial OsmY and nodulation domain - - - 0.00000000000000000000008388 105.0
HFD2_k127_5969638_6 - - - - 0.0000001311 61.0
HFD2_k127_602126_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 562.0
HFD2_k127_602126_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 375.0
HFD2_k127_602126_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 362.0
HFD2_k127_602126_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 307.0
HFD2_k127_602126_4 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000006198 179.0
HFD2_k127_602126_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000005913 169.0
HFD2_k127_602126_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000004465 158.0
HFD2_k127_6118680_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 573.0
HFD2_k127_6118680_1 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 533.0
HFD2_k127_6118680_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 480.0
HFD2_k127_6118680_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 315.0
HFD2_k127_6118680_4 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000004982 178.0
HFD2_k127_6118680_5 Urate oxidase N-terminal - - - 0.00000000000000000000000003612 108.0
HFD2_k127_6149433_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 1.589e-285 893.0
HFD2_k127_6149433_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 562.0
HFD2_k127_6149433_10 Auxin binding protein - - - 0.000000063 60.0
HFD2_k127_6149433_11 - - - - 0.00002989 55.0
HFD2_k127_6149433_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 582.0
HFD2_k127_6149433_3 Ligated ion channel L-glutamate- and glycine-binding site K02030,K10036 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 432.0
HFD2_k127_6149433_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 395.0
HFD2_k127_6149433_5 PFAM porin Gram-negative type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 385.0
HFD2_k127_6149433_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HFD2_k127_6149433_7 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 347.0
HFD2_k127_6149433_8 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007661 280.0
HFD2_k127_6149433_9 - - - - 0.00000000000000000000000000000000000000000000000000000000001526 225.0
HFD2_k127_615351_0 Threonine synthase K01733 - 4.2.3.1 3.915e-243 765.0
HFD2_k127_615351_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 542.0
HFD2_k127_615351_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 495.0
HFD2_k127_615351_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000277 115.0
HFD2_k127_6158870_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 4.18e-289 896.0
HFD2_k127_6158870_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 460.0
HFD2_k127_6158870_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 432.0
HFD2_k127_6158870_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 419.0
HFD2_k127_6158870_4 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 266.0
HFD2_k127_6158870_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000001586 187.0
HFD2_k127_6161964_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.662e-216 674.0
HFD2_k127_6161964_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 543.0
HFD2_k127_6161964_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 418.0
HFD2_k127_6161964_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 291.0
HFD2_k127_6161964_4 SWI complex, BAF60b domains - - - 0.000000000000682 68.0
HFD2_k127_6164612_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 599.0
HFD2_k127_6164612_1 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 406.0
HFD2_k127_6164612_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 355.0
HFD2_k127_6164612_3 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000001021 227.0
HFD2_k127_6164612_4 - - - - 0.00000000000000000000000000001964 122.0
HFD2_k127_6168603_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 515.0
HFD2_k127_6168603_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 470.0
HFD2_k127_6168603_10 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.00000000000000001852 98.0
HFD2_k127_6168603_11 Chitinase class I K20547 - 3.2.1.14 0.00000000001338 79.0
HFD2_k127_6168603_12 Antibiotic synthesis protein MbtH K05375 - - 0.0001146 49.0
HFD2_k127_6168603_2 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 458.0
HFD2_k127_6168603_3 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 396.0
HFD2_k127_6168603_4 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 396.0
HFD2_k127_6168603_5 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 343.0
HFD2_k127_6168603_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001011 252.0
HFD2_k127_6168603_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000001178 191.0
HFD2_k127_6168603_8 metallopeptidase activity K01179 - 3.2.1.4 0.000000000000000000000000001644 132.0
HFD2_k127_6168603_9 H-NS histone family K03746 - - 0.000000000000000000001964 100.0
HFD2_k127_6168652_0 Transcriptional regulator K13634,K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 477.0
HFD2_k127_6168652_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 347.0
HFD2_k127_6168652_2 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 256.0
HFD2_k127_6168652_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000001666 199.0
HFD2_k127_6168652_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000242 98.0
HFD2_k127_6168652_5 bacterial-type flagellum-dependent cell motility - - - 0.00000001714 68.0
HFD2_k127_6169187_0 Diguanylate cyclase - - - 5.353e-220 714.0
HFD2_k127_6169187_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 4.429e-217 689.0
HFD2_k127_6169187_10 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 352.0
HFD2_k127_6169187_11 phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 301.0
HFD2_k127_6169187_12 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006191 261.0
HFD2_k127_6169187_13 Domain of unknown function (DUF1840) - - - 0.000000000000000000000000000000000000117 149.0
HFD2_k127_6169187_14 TIR domain - - - 0.00000000000000000000000000000001854 141.0
HFD2_k127_6169187_15 Lysyl oxidase - - - 0.0000000000000000000000000007181 127.0
HFD2_k127_6169187_17 response regulator - - - 0.000000000000002134 87.0
HFD2_k127_6169187_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.748e-199 649.0
HFD2_k127_6169187_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 5.694e-194 615.0
HFD2_k127_6169187_4 PFAM fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 558.0
HFD2_k127_6169187_5 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 559.0
HFD2_k127_6169187_6 Alanine racemase K19967 - 4.1.2.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 509.0
HFD2_k127_6169187_7 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 507.0
HFD2_k127_6169187_8 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 499.0
HFD2_k127_6169187_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 389.0
HFD2_k127_6192875_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 9.183e-205 646.0
HFD2_k127_6192875_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001546 264.0
HFD2_k127_6192875_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000004677 209.0
HFD2_k127_6192875_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000006166 209.0
HFD2_k127_6192875_4 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000002266 199.0
HFD2_k127_6194001_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.056e-262 835.0
HFD2_k127_6194001_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 447.0
HFD2_k127_6194001_2 the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 384.0
HFD2_k127_6194001_3 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 347.0
HFD2_k127_6194001_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
HFD2_k127_6194001_5 Isoquinoline 1-oxidoreductase K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000004413 252.0
HFD2_k127_6194001_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000002552 220.0
HFD2_k127_6194001_7 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000007427 81.0
HFD2_k127_6222092_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 481.0
HFD2_k127_6222092_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 409.0
HFD2_k127_6222092_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 388.0
HFD2_k127_6222092_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
HFD2_k127_6224433_0 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 514.0
HFD2_k127_6224433_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 312.0
HFD2_k127_6224433_2 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 301.0
HFD2_k127_6224433_3 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009152 276.0
HFD2_k127_6224433_4 Sporulation domain protein - - - 0.000000000000000000000000000000000000000004479 173.0
HFD2_k127_6224433_5 DNA topoisomerase, type IA, central domain protein K03169 - 5.99.1.2 0.00000000000000000000004192 104.0
HFD2_k127_6230112_0 Protein of unknown function - - - 0.0 1487.0
HFD2_k127_6230112_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1322.0
HFD2_k127_6230112_10 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 345.0
HFD2_k127_6230112_11 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002516 282.0
HFD2_k127_6230112_12 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000001138 248.0
HFD2_k127_6230112_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000001127 243.0
HFD2_k127_6230112_14 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000364 177.0
HFD2_k127_6230112_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5.889e-314 969.0
HFD2_k127_6230112_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.617e-313 968.0
HFD2_k127_6230112_4 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 603.0
HFD2_k127_6230112_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 573.0
HFD2_k127_6230112_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 539.0
HFD2_k127_6230112_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 396.0
HFD2_k127_6230112_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 377.0
HFD2_k127_6230112_9 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 372.0
HFD2_k127_6236375_0 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 613.0
HFD2_k127_6236375_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 539.0
HFD2_k127_6236375_2 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 376.0
HFD2_k127_6236375_3 - K12140 - - 0.000000000000000000000000000000000000000000000000000002018 212.0
HFD2_k127_6236375_4 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000002828 177.0
HFD2_k127_6237214_0 TIGRFAM type VI secretion protein, EvpB VC_A0108 family K11900 - - 3.615e-274 848.0
HFD2_k127_6237214_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 286.0
HFD2_k127_6237214_2 hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001948 260.0
HFD2_k127_6237214_3 TIGRFAM type VI secretion-associated protein, ImpA family K11902 - - 0.00000000000000000000000000000000000000000000000000000000000006938 226.0
HFD2_k127_6237214_4 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000002028 189.0
HFD2_k127_6237214_5 Type VI secretion system effector, Hcp - - - 0.000000000000000001785 91.0
HFD2_k127_6243880_0 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1583.0
HFD2_k127_6243880_1 belongs to the aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 1.894e-267 829.0
HFD2_k127_6243880_2 glutamine synthetase K01915 - 6.3.1.2 1.133e-213 670.0
HFD2_k127_6243880_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 611.0
HFD2_k127_6243880_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 561.0
HFD2_k127_6243880_5 transport system permease K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 422.0
HFD2_k127_6243880_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 387.0
HFD2_k127_6243880_7 transport system permease K11075 - - 0.000000000000000000001371 93.0
HFD2_k127_6254775_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1205.0
HFD2_k127_6254775_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.319e-268 867.0
HFD2_k127_6254775_10 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000002044 237.0
HFD2_k127_6254775_11 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000003507 216.0
HFD2_k127_6254775_12 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000001071 219.0
HFD2_k127_6254775_13 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000001563 171.0
HFD2_k127_6254775_14 psiF repeat - - - 0.00000000000000000000001256 117.0
HFD2_k127_6254775_2 Serine threonine protein kinase K12132 - 2.7.11.1 1.379e-202 670.0
HFD2_k127_6254775_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 531.0
HFD2_k127_6254775_4 Tryptophan halogenase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 534.0
HFD2_k127_6254775_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 447.0
HFD2_k127_6254775_6 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 421.0
HFD2_k127_6254775_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 374.0
HFD2_k127_6254775_8 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 344.0
HFD2_k127_6254775_9 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 259.0
HFD2_k127_6254821_0 Bacterial extracellular solute-binding protein K02027 - - 1.173e-231 743.0
HFD2_k127_6254821_1 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 599.0
HFD2_k127_6254821_10 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 380.0
HFD2_k127_6254821_11 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 346.0
HFD2_k127_6254821_12 Class II aldolase K01628,K22130 - 4.1.1.104,4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 338.0
HFD2_k127_6254821_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 342.0
HFD2_k127_6254821_14 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000203 105.0
HFD2_k127_6254821_15 type VI secretion system effector K11903 - - 0.000000000000004977 82.0
HFD2_k127_6254821_2 PFAM NAD-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 510.0
HFD2_k127_6254821_3 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 502.0
HFD2_k127_6254821_4 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 468.0
HFD2_k127_6254821_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 411.0
HFD2_k127_6254821_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 426.0
HFD2_k127_6254821_7 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 404.0
HFD2_k127_6254821_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 363.0
HFD2_k127_6254821_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 358.0
HFD2_k127_6263963_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 6.67e-267 824.0
HFD2_k127_6263963_1 Thiamine monophosphate synthase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 621.0
HFD2_k127_6263963_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 436.0
HFD2_k127_6263963_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 417.0
HFD2_k127_6263963_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 397.0
HFD2_k127_6263963_5 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 328.0
HFD2_k127_6263963_6 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
HFD2_k127_6263963_7 ThiS family K03154 - - 0.00000000005953 75.0
HFD2_k127_6283932_0 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
HFD2_k127_6283932_1 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 365.0
HFD2_k127_6283932_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 376.0
HFD2_k127_6283932_3 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002615 280.0
HFD2_k127_6283932_4 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006729 235.0
HFD2_k127_6283932_5 Protein of unknown function, DUF393 - - - 0.00000000007469 64.0
HFD2_k127_6283932_6 gluconolactonase activity K00368,K07004 - 1.7.2.1 0.00000007983 64.0
HFD2_k127_6314571_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1592.0
HFD2_k127_6314571_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.2e-217 680.0
HFD2_k127_6314571_2 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 485.0
HFD2_k127_6314571_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 440.0
HFD2_k127_6314571_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 431.0
HFD2_k127_6314571_5 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 432.0
HFD2_k127_6314571_6 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 400.0
HFD2_k127_6314571_7 TIGRFAM TIGR03790 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 407.0
HFD2_k127_6314571_8 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
HFD2_k127_633438_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.06e-272 846.0
HFD2_k127_633438_1 Belongs to the GARS family K01945 - 6.3.4.13 6.207e-224 703.0
HFD2_k127_633438_10 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000006719 237.0
HFD2_k127_633438_11 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000003603 205.0
HFD2_k127_633438_12 - - - - 0.00000000000000000000000000000000000000002974 159.0
HFD2_k127_633438_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002697 138.0
HFD2_k127_633438_14 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000003627 129.0
HFD2_k127_633438_15 ChrR Cupin-like domain - - - 0.000000000000000000007119 98.0
HFD2_k127_633438_17 2TM domain - - - 0.0000000000000007574 89.0
HFD2_k127_633438_18 - - - - 0.000000000009348 72.0
HFD2_k127_633438_19 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000008512 58.0
HFD2_k127_633438_2 Peptidase M14, carboxypeptidase A - - - 1.588e-199 643.0
HFD2_k127_633438_3 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 605.0
HFD2_k127_633438_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 529.0
HFD2_k127_633438_5 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 416.0
HFD2_k127_633438_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 350.0
HFD2_k127_633438_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 326.0
HFD2_k127_633438_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000006539 244.0
HFD2_k127_633438_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000000000000001564 222.0
HFD2_k127_6369547_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 2.591e-237 753.0
HFD2_k127_6369547_1 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 540.0
HFD2_k127_6369547_2 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000002202 229.0
HFD2_k127_6369547_3 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000001817 181.0
HFD2_k127_6369547_4 flagellar export protein FliJ K02413 - - 0.000000000000000000000000005133 116.0
HFD2_k127_6378947_0 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.0 1053.0
HFD2_k127_6378947_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 590.0
HFD2_k127_6378947_10 Pathogenicity locus K07343 - - 0.00000000000000000000000009215 107.0
HFD2_k127_6378947_11 - - - - 0.000000000000002739 91.0
HFD2_k127_6378947_12 - - - - 0.000000000000203 76.0
HFD2_k127_6378947_13 - - - - 0.0000000004902 69.0
HFD2_k127_6378947_2 Major Facilitator Superfamily K19577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 484.0
HFD2_k127_6378947_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 377.0
HFD2_k127_6378947_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 329.0
HFD2_k127_6378947_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 249.0
HFD2_k127_6378947_6 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000001509 205.0
HFD2_k127_6378947_7 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000004871 213.0
HFD2_k127_6378947_8 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000945 192.0
HFD2_k127_6378947_9 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000008687 206.0
HFD2_k127_6381617_0 TonB dependent receptor K02014 - - 8.727e-243 771.0
HFD2_k127_6381617_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 1.726e-224 702.0
HFD2_k127_6381617_2 Ferredoxin--NADP reductase K00384 - 1.8.1.9 2.326e-210 657.0
HFD2_k127_6381617_3 PFAM phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 587.0
HFD2_k127_6381617_4 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 341.0
HFD2_k127_6381617_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000001794 211.0
HFD2_k127_6411846_0 FAD linked oxidase domain protein - - - 0.0 2197.0
HFD2_k127_6411846_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.716e-268 854.0
HFD2_k127_6411846_10 Belongs to the ABC transporter superfamily K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000003 240.0
HFD2_k127_6411846_2 PFAM extracellular solute-binding protein family 1 K05813 - - 1.81e-250 782.0
HFD2_k127_6411846_3 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 557.0
HFD2_k127_6411846_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 556.0
HFD2_k127_6411846_5 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 480.0
HFD2_k127_6411846_6 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 505.0
HFD2_k127_6411846_7 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 449.0
HFD2_k127_6411846_8 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 464.0
HFD2_k127_6411846_9 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 457.0
HFD2_k127_6412142_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 9.16e-199 630.0
HFD2_k127_6412142_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 595.0
HFD2_k127_6412142_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 426.0
HFD2_k127_6412142_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 359.0
HFD2_k127_6412142_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007499 249.0
HFD2_k127_6412142_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000008573 188.0
HFD2_k127_6412142_6 - - - - 0.0000000000000000000000000000000000000000000008992 176.0
HFD2_k127_6417517_0 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
HFD2_k127_6417517_1 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 463.0
HFD2_k127_6417517_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 437.0
HFD2_k127_6417517_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002258 275.0
HFD2_k127_6417517_4 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
HFD2_k127_6417517_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000001223 171.0
HFD2_k127_6417517_6 Protein of unknown function (DUF1631) - - - 0.000000000006002 65.0
HFD2_k127_6459435_0 Histidine kinase K07646 - 2.7.13.3 0.0 1105.0
HFD2_k127_6459435_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1058.0
HFD2_k127_6459435_10 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 457.0
HFD2_k127_6459435_11 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 396.0
HFD2_k127_6459435_12 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 386.0
HFD2_k127_6459435_13 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 383.0
HFD2_k127_6459435_14 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 344.0
HFD2_k127_6459435_15 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 334.0
HFD2_k127_6459435_16 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 329.0
HFD2_k127_6459435_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003957 267.0
HFD2_k127_6459435_18 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
HFD2_k127_6459435_19 TIGRFAM diguanylate cyclase K13069,K21085 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000001828 272.0
HFD2_k127_6459435_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.395e-284 886.0
HFD2_k127_6459435_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003837 264.0
HFD2_k127_6459435_21 transcriptional K13639 - - 0.0000000000000000000000000000000000000000000000000001494 189.0
HFD2_k127_6459435_22 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000004366 181.0
HFD2_k127_6459435_23 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000002211 168.0
HFD2_k127_6459435_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 4.263e-232 727.0
HFD2_k127_6459435_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.302e-231 723.0
HFD2_k127_6459435_5 K+ potassium transporter K03549 - - 3.025e-217 692.0
HFD2_k127_6459435_6 Belongs to the ClpA ClpB family K03694 - - 4.418e-199 622.0
HFD2_k127_6459435_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 591.0
HFD2_k127_6459435_8 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 526.0
HFD2_k127_6459435_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 467.0
HFD2_k127_650990_0 Methylmalonyl-CoA mutase K01847,K20906 - 5.4.99.2,5.4.99.64 0.0 1255.0
HFD2_k127_650990_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.956e-317 974.0
HFD2_k127_650990_2 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 610.0
HFD2_k127_650990_3 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 436.0
HFD2_k127_650990_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 317.0
HFD2_k127_650990_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000006967 134.0
HFD2_k127_6532921_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 3.827e-231 725.0
HFD2_k127_6532921_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 443.0
HFD2_k127_6532921_2 Regulator K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 405.0
HFD2_k127_6532921_3 cytochrome C oxidase K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 363.0
HFD2_k127_6532921_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 338.0
HFD2_k127_6532921_5 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002071 263.0
HFD2_k127_6532921_6 - - - - 0.00000000000000000002903 98.0
HFD2_k127_6532921_7 Cbb3-type cytochrome oxidase K00407 - - 0.000000000009319 66.0
HFD2_k127_656323_0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 8.177e-215 676.0
HFD2_k127_656323_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 383.0
HFD2_k127_656323_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 294.0
HFD2_k127_656323_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001252 280.0
HFD2_k127_656323_4 Endoribonuclease L-PSP K09021 - - 0.0000000000000000000000000000000000000000000000003042 179.0
HFD2_k127_656323_5 TIGRFAM ATP synthase, F0 - - - 0.00000000000000000000000000000000000001221 146.0
HFD2_k127_656323_6 Cytochrome P460 - - - 0.00000000000000000000000122 114.0
HFD2_k127_656323_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000006344 94.0
HFD2_k127_656323_8 Tripartite tricarboxylate transporter family receptor - - - 0.00002976 46.0
HFD2_k127_6573829_0 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 393.0
HFD2_k127_6573829_1 C4-dicarboxylate transporter malic acid transport protein K03304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 343.0
HFD2_k127_6573829_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 283.0
HFD2_k127_6573829_3 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000232 167.0
HFD2_k127_6573829_4 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000004028 127.0
HFD2_k127_6573829_5 Metal-sensitive transcriptional repressor - - - 0.000000000000000000000000009725 124.0
HFD2_k127_6573829_6 - - - - 0.000000000000000000000005133 104.0
HFD2_k127_6586380_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 6.254e-219 691.0
HFD2_k127_6586380_1 Permease, YjgP YjgQ K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 480.0
HFD2_k127_6586380_2 Transcriptional regulator, LysR family K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 381.0
HFD2_k127_6586380_3 Permease, YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006229 269.0
HFD2_k127_6586380_4 Permease, YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000006295 227.0
HFD2_k127_6586380_5 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000009418 158.0
HFD2_k127_6586380_6 CbiX K03795 - 4.99.1.3 0.000000000000000000000000000000000003944 146.0
HFD2_k127_6586380_7 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000283 110.0
HFD2_k127_6586380_8 - - - - 0.00000000000000001558 93.0
HFD2_k127_6598147_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 6.172e-240 747.0
HFD2_k127_6598147_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 533.0
HFD2_k127_6598147_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 494.0
HFD2_k127_6598147_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000002642 156.0
HFD2_k127_6598147_4 Tetratricopeptide repeat-like domain - - - 0.0000000000002595 70.0
HFD2_k127_66171_0 Protein of unknown function (DUF1631) - - - 0.0 1024.0
HFD2_k127_66171_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1002.0
HFD2_k127_66171_2 Proton-conducting membrane transporter K12137 - - 2.333e-250 786.0
HFD2_k127_66171_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 514.0
HFD2_k127_66171_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 495.0
HFD2_k127_66171_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000000002847 163.0
HFD2_k127_66171_6 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000001893 166.0
HFD2_k127_66171_7 copG family - - - 0.0000000000000000001069 97.0
HFD2_k127_6621672_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2159.0
HFD2_k127_6621672_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.567e-203 656.0
HFD2_k127_6621672_2 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 500.0
HFD2_k127_6682243_0 Amidohydrolase K10220,K14333 - 4.1.1.46,4.2.1.83 4.349e-208 648.0
HFD2_k127_6682243_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 416.0
HFD2_k127_6682243_2 LysR substrate binding domain K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 374.0
HFD2_k127_6682243_3 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 301.0
HFD2_k127_6682243_4 PFAM Dimethylmenaquinone methyltransferase K10218 - 4.1.3.17 0.00000000000002483 76.0
HFD2_k127_6704833_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 7.223e-289 898.0
HFD2_k127_6704833_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.041e-223 698.0
HFD2_k127_6704833_10 Nitrogen fixation protein - - - 0.0000000000000000000000000000000000000000000000000001351 186.0
HFD2_k127_6704833_11 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000002104 183.0
HFD2_k127_6704833_12 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.000000000000000000000000000000000000000269 167.0
HFD2_k127_6704833_13 Rop-like - - - 0.00000000000000000000005135 99.0
HFD2_k127_6704833_2 Electron transfer flavoprotein, alpha subunit K03522 - - 1.394e-207 649.0
HFD2_k127_6704833_3 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 546.0
HFD2_k127_6704833_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 532.0
HFD2_k127_6704833_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000306 249.0
HFD2_k127_6704833_6 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001924 222.0
HFD2_k127_6704833_7 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000000000000378 208.0
HFD2_k127_6704833_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000001437 195.0
HFD2_k127_6704833_9 NifQ K15790 - - 0.00000000000000000000000000000000000000000000000000007169 195.0
HFD2_k127_6719268_0 GAF modulated sigma54 specific transcriptional regulator, Fis family K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 490.0
HFD2_k127_6719268_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 355.0
HFD2_k127_6719268_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 306.0
HFD2_k127_6719268_3 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 305.0
HFD2_k127_6719268_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
HFD2_k127_6719268_5 Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000007275 213.0
HFD2_k127_6719268_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000007128 186.0
HFD2_k127_6739634_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 491.0
HFD2_k127_6739634_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 427.0
HFD2_k127_6739634_2 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 374.0
HFD2_k127_6739634_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004175 243.0
HFD2_k127_6752491_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 608.0
HFD2_k127_6752491_1 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 530.0
HFD2_k127_6752491_2 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 286.0
HFD2_k127_6752491_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000094 287.0
HFD2_k127_6752491_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
HFD2_k127_6752491_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000008183 139.0
HFD2_k127_6752545_0 Glucose inhibited division protein A - - - 2.404e-259 806.0
HFD2_k127_6752545_1 Protein of unknown function (DUF521) K09123 - - 2.9e-222 696.0
HFD2_k127_6752545_2 PFAM regulatory protein, IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 359.0
HFD2_k127_6752545_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 339.0
HFD2_k127_6752545_4 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000000009681 231.0
HFD2_k127_675394_0 Major facilitator superfamily K07552,K18552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 447.0
HFD2_k127_675394_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 403.0
HFD2_k127_675394_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 411.0
HFD2_k127_675394_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 402.0
HFD2_k127_675394_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 285.0
HFD2_k127_675394_5 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000004841 224.0
HFD2_k127_675394_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000004012 213.0
HFD2_k127_675394_7 - - - - 0.00000000000000000000000000000000153 134.0
HFD2_k127_6760472_0 Type II secretory pathway, component ExeA K02450 - - 9.949e-199 634.0
HFD2_k127_6760472_1 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 420.0
HFD2_k127_6760472_2 Bacterial periplasmic substrate-binding proteins K02030,K10022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 413.0
HFD2_k127_6760472_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 339.0
HFD2_k127_6760472_4 Polar amino acid ABC transporter, inner membrane K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
HFD2_k127_6760472_5 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 308.0
HFD2_k127_6760472_6 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000002018 211.0
HFD2_k127_6760472_7 Thioredoxin-like domain K03805 - - 0.000000000000000000000000000000000000000009527 161.0
HFD2_k127_6760472_8 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000000000223 160.0
HFD2_k127_6784682_0 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 369.0
HFD2_k127_6784682_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 362.0
HFD2_k127_6784682_2 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 333.0
HFD2_k127_6784682_3 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 299.0
HFD2_k127_6784682_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000006491 207.0
HFD2_k127_6784682_5 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000002497 124.0
HFD2_k127_6794659_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1164.0
HFD2_k127_6794659_1 indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 3.546e-320 1007.0
HFD2_k127_6794659_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 323.0
HFD2_k127_6794659_11 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
HFD2_k127_6794659_12 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000000000000000000000000000000007216 164.0
HFD2_k127_6794659_13 acyl-coA-binding protein - - - 0.00000000000000000000000000000000000000003045 154.0
HFD2_k127_6794659_2 Peptidase dimerisation domain - - - 5.343e-231 719.0
HFD2_k127_6794659_3 Protein of unknown function (DUF1298) - - - 1.288e-227 712.0
HFD2_k127_6794659_4 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 578.0
HFD2_k127_6794659_5 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 539.0
HFD2_k127_6794659_6 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 543.0
HFD2_k127_6794659_7 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 496.0
HFD2_k127_6794659_8 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 488.0
HFD2_k127_6794659_9 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 471.0
HFD2_k127_6796304_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1774.0
HFD2_k127_6796304_1 DinB superfamily - - - 9.618e-202 636.0
HFD2_k127_6796304_10 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000005283 206.0
HFD2_k127_6796304_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 458.0
HFD2_k127_6796304_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 454.0
HFD2_k127_6796304_4 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 438.0
HFD2_k127_6796304_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 425.0
HFD2_k127_6796304_6 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 366.0
HFD2_k127_6796304_7 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
HFD2_k127_6796304_8 Flavodoxin domain K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002382 277.0
HFD2_k127_6796304_9 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000001183 214.0
HFD2_k127_6848466_0 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 566.0
HFD2_k127_6848466_1 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 380.0
HFD2_k127_6848466_2 Regulatory protein GntR HTH K11475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 304.0
HFD2_k127_6848466_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002984 222.0
HFD2_k127_6863492_0 Peptidase family M1 domain - - - 0.0 1251.0
HFD2_k127_6863492_1 ASPIC and UnbV - - - 2.161e-280 884.0
HFD2_k127_6863492_10 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 439.0
HFD2_k127_6863492_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 427.0
HFD2_k127_6863492_12 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 426.0
HFD2_k127_6863492_13 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 427.0
HFD2_k127_6863492_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 389.0
HFD2_k127_6863492_15 PFAM regulatory protein LacI K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 380.0
HFD2_k127_6863492_16 ABC transporter K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
HFD2_k127_6863492_17 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 268.0
HFD2_k127_6863492_18 Dak2 K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000000004021 192.0
HFD2_k127_6863492_19 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000008379 137.0
HFD2_k127_6863492_2 Bacterial extracellular solute-binding protein K02027 - - 6.149e-239 763.0
HFD2_k127_6863492_20 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000000000000003969 153.0
HFD2_k127_6863492_21 - - - - 0.00000000000002496 85.0
HFD2_k127_6863492_3 cell adhesion involved in biofilm formation - - - 6.931e-234 731.0
HFD2_k127_6863492_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 551.0
HFD2_k127_6863492_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 550.0
HFD2_k127_6863492_6 alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 538.0
HFD2_k127_6863492_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 516.0
HFD2_k127_6863492_8 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 500.0
HFD2_k127_6863492_9 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 490.0
HFD2_k127_6900609_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 476.0
HFD2_k127_6900609_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003523 286.0
HFD2_k127_6900609_2 Domain of unknown function (DUF1956) - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
HFD2_k127_6911331_0 Outer membrane receptor - - - 1.09e-284 906.0
HFD2_k127_6911331_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 584.0
HFD2_k127_6911331_2 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 441.0
HFD2_k127_6911331_3 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 443.0
HFD2_k127_6911331_4 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 420.0
HFD2_k127_6911331_5 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 369.0
HFD2_k127_6911331_6 Beta-glucosidase K05350 - 3.2.1.21 0.000000000000000000004388 92.0
HFD2_k127_6913501_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.294e-294 908.0
HFD2_k127_6913501_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 583.0
HFD2_k127_6913501_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 533.0
HFD2_k127_6913501_3 Transcriptional regulator, LysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 476.0
HFD2_k127_6913501_4 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 408.0
HFD2_k127_6913501_5 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 359.0
HFD2_k127_6913501_6 Outer membrane efflux protein K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004284 280.0
HFD2_k127_6913501_7 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
HFD2_k127_6913501_8 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000222 141.0
HFD2_k127_6913501_9 - - - - 0.0000000000000000001971 93.0
HFD2_k127_6923803_0 Male sterility protein - - - 2.228e-236 733.0
HFD2_k127_6923803_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 540.0
HFD2_k127_6923803_2 EamA-like transporter family K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
HFD2_k127_6923803_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 287.0
HFD2_k127_6923803_4 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000006753 212.0
HFD2_k127_6956870_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002158 279.0
HFD2_k127_6956870_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000005268 270.0
HFD2_k127_6956870_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000005642 236.0
HFD2_k127_6956870_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000002629 177.0
HFD2_k127_6982735_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 453.0
HFD2_k127_6982735_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 396.0
HFD2_k127_6982735_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 390.0
HFD2_k127_6982735_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 372.0
HFD2_k127_6982735_4 NAD-dependent epimerase dehydratase K07118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
HFD2_k127_6982735_5 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000000000000000002575 243.0
HFD2_k127_6982735_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000002831 196.0
HFD2_k127_6982735_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000531 128.0
HFD2_k127_6982735_8 - - - - 0.0000000000002988 75.0
HFD2_k127_7030843_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 443.0
HFD2_k127_7030843_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD2_k127_7030843_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000003549 230.0
HFD2_k127_7042936_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006082 282.0
HFD2_k127_7042936_1 PFAM GumN family protein K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006393 273.0
HFD2_k127_7042936_2 Glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006653 263.0
HFD2_k127_7042936_3 Fumarylacetoacetate (Faa) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003912 235.0
HFD2_k127_7042936_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000003636 201.0
HFD2_k127_7042936_5 FIST_C - - - 0.0000000000000000000000000000000000000000003304 172.0
HFD2_k127_7063106_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 501.0
HFD2_k127_7063106_1 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002788 284.0
HFD2_k127_7063106_2 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD2_k127_7063106_3 transcriptional regulator, AraC family - - - 0.000000000000000000000000000000000000000002795 157.0
HFD2_k127_7072436_0 Putative modulator of DNA gyrase - - - 1.012e-197 627.0
HFD2_k127_7072436_1 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 544.0
HFD2_k127_7072436_2 Periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001874 279.0
HFD2_k127_7072436_3 cytochrome C K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002468 250.0
HFD2_k127_7072436_4 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000000000003362 188.0
HFD2_k127_7072436_5 N-acylglucosamine 2-epimerase - - - 0.0000000000000000000000001306 105.0
HFD2_k127_7079468_0 GAF domain K21405 - - 5.066e-231 730.0
HFD2_k127_7079468_1 Glucose / Sorbosone dehydrogenase - - - 5.272e-227 719.0
HFD2_k127_7079468_2 Signal transduction histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 527.0
HFD2_k127_7079468_3 PFAM Cytochrome C - - - 0.000000000000000000000001797 113.0
HFD2_k127_7080012_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.927e-230 716.0
HFD2_k127_7080012_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.642e-223 696.0
HFD2_k127_7080012_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 1.296e-198 623.0
HFD2_k127_7080012_3 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 417.0
HFD2_k127_7080012_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 400.0
HFD2_k127_7080012_5 Entericidin - - - 0.00000001807 57.0
HFD2_k127_7083838_0 PFAM extracellular solute-binding protein family 5 K12368 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 616.0
HFD2_k127_7083838_1 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 593.0
HFD2_k127_7083838_2 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 508.0
HFD2_k127_7083838_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 499.0
HFD2_k127_7083838_4 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 510.0
HFD2_k127_7083838_5 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 464.0
HFD2_k127_7083838_6 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 396.0
HFD2_k127_7093316_0 AMP-binding enzyme C-terminal domain - - - 1.637e-289 900.0
HFD2_k127_7093316_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.289e-273 852.0
HFD2_k127_7093316_2 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 356.0
HFD2_k127_7093316_3 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001961 291.0
HFD2_k127_7093316_4 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000000000569 224.0
HFD2_k127_7093316_5 Protein conserved in bacteria K09984 - - 0.0000000000000000000000000000000000000000000000000002302 186.0
HFD2_k127_7093316_6 - - - - 0.000000000003932 70.0
HFD2_k127_7109115_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1415.0
HFD2_k127_7109115_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0 1143.0
HFD2_k127_7109115_10 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000005628 250.0
HFD2_k127_7109115_11 Phosphopantetheine attachment site - - - 0.00000000000000000000001151 104.0
HFD2_k127_7109115_12 Domain of unknown function (DUF4266) - - - 0.000000000000001553 83.0
HFD2_k127_7109115_2 fad dependent oxidoreductase K03379 - 1.14.13.22 1.887e-205 665.0
HFD2_k127_7109115_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 460.0
HFD2_k127_7109115_4 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 460.0
HFD2_k127_7109115_5 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 387.0
HFD2_k127_7109115_6 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 337.0
HFD2_k127_7109115_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 293.0
HFD2_k127_7109115_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006067 274.0
HFD2_k127_7109115_9 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001216 233.0
HFD2_k127_7110847_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 620.0
HFD2_k127_7110847_1 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 352.0
HFD2_k127_7110847_2 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001885 289.0
HFD2_k127_7110847_3 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000001219 207.0
HFD2_k127_7110847_4 - - - - 0.000000000000000000000000004761 121.0
HFD2_k127_7114_0 peptidase U62, modulator of DNA gyrase K03592 - - 3.984e-232 725.0
HFD2_k127_7114_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.802e-205 642.0
HFD2_k127_7114_2 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 474.0
HFD2_k127_7114_3 molybdenum cofactor K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
HFD2_k127_7114_4 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 324.0
HFD2_k127_7114_5 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000007446 196.0
HFD2_k127_7116292_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1048.0
HFD2_k127_7116292_1 Belongs to the glycosyl hydrolase 13 family - - - 1.596e-211 664.0
HFD2_k127_7116292_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 422.0
HFD2_k127_7116292_3 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 294.0
HFD2_k127_7116292_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004602 273.0
HFD2_k127_7116292_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000464 136.0
HFD2_k127_7135738_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1049.0
HFD2_k127_7135738_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 508.0
HFD2_k127_7135738_2 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 432.0
HFD2_k127_7135738_3 Response regulator of the LytR AlgR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 400.0
HFD2_k127_7135738_4 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 357.0
HFD2_k127_7135738_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008551 263.0
HFD2_k127_7135738_6 - - - - 0.000000000000000000000000000000000000000000000000007854 193.0
HFD2_k127_7135738_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000001429 161.0
HFD2_k127_7135738_8 membrane - - - 0.0000000000000000000000000000000000000000006038 177.0
HFD2_k127_7148501_0 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1659.0
HFD2_k127_7148501_1 fad dependent oxidoreductase K07137 - - 3.233e-281 872.0
HFD2_k127_7148501_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 389.0
HFD2_k127_7148501_11 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 372.0
HFD2_k127_7148501_12 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 351.0
HFD2_k127_7148501_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 340.0
HFD2_k127_7148501_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
HFD2_k127_7148501_15 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 304.0
HFD2_k127_7148501_16 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000055 271.0
HFD2_k127_7148501_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009103 259.0
HFD2_k127_7148501_18 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000001082 183.0
HFD2_k127_7148501_19 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000622 180.0
HFD2_k127_7148501_2 Peptidase dimerisation domain - - - 2.165e-254 797.0
HFD2_k127_7148501_20 - - - - 0.000000000000000000000000000000000000006574 149.0
HFD2_k127_7148501_21 Histidine kinase - - - 0.0000000000000000000000000000002315 127.0
HFD2_k127_7148501_22 Zinc-finger domain - - - 0.000000000000000000000000000005224 119.0
HFD2_k127_7148501_23 - - - - 0.0000000005568 69.0
HFD2_k127_7148501_24 Anti-sigma-K factor rskA - - - 0.000000001228 69.0
HFD2_k127_7148501_25 viral genome integration into host DNA - - - 0.0006291 42.0
HFD2_k127_7148501_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.736e-252 782.0
HFD2_k127_7148501_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 585.0
HFD2_k127_7148501_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 526.0
HFD2_k127_7148501_6 hydrolase of the alpha K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 497.0
HFD2_k127_7148501_7 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 537.0
HFD2_k127_7148501_8 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
HFD2_k127_7148501_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 416.0
HFD2_k127_7171161_0 carbohydrate binding K13688 - - 0.0 1899.0
HFD2_k127_7171161_1 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001319 265.0
HFD2_k127_71776_0 histidine kinase A domain protein - - - 4.134e-216 680.0
HFD2_k127_71776_1 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HFD2_k127_71776_2 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 385.0
HFD2_k127_71776_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 390.0
HFD2_k127_71776_4 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000108 224.0
HFD2_k127_7181877_0 Cytochrome D1 heme domain - - - 1.69e-281 868.0
HFD2_k127_7181877_1 Cytochrome b(N-terminal)/b6/petB - - - 1.293e-265 842.0
HFD2_k127_7181877_11 Belongs to the transketolase family K00615 - 2.2.1.1 0.0002749 50.0
HFD2_k127_7181877_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 432.0
HFD2_k127_7181877_3 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 306.0
HFD2_k127_7181877_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 282.0
HFD2_k127_7181877_5 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000003199 239.0
HFD2_k127_7181877_6 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000002667 196.0
HFD2_k127_7181877_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000001698 179.0
HFD2_k127_7181877_8 electron transfer activity K08738 - - 0.0000000000000000000000000000000009465 135.0
HFD2_k127_7181877_9 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000169 108.0
HFD2_k127_7189299_0 Aminotransferase K01845 - 5.4.3.8 4.468e-226 708.0
HFD2_k127_7189299_1 PFAM chemotaxis sensory transducer K02660 - - 8.275e-203 648.0
HFD2_k127_7189299_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 476.0
HFD2_k127_7189299_3 response regulator, receiver K02658 - - 0.000000000000000000000000000000000000000000000000000000000000000007741 225.0
HFD2_k127_7189299_4 Response regulator receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000151 225.0
HFD2_k127_7189299_5 PFAM CheW domain protein K02659 - - 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
HFD2_k127_7189299_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000464 196.0
HFD2_k127_7189299_7 rubredoxin - - - 0.0000000000000000000000000000000004405 130.0
HFD2_k127_7191325_0 peptidase dimerisation domain protein - - - 1.57e-210 674.0
HFD2_k127_7191325_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 591.0
HFD2_k127_7191325_2 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 406.0
HFD2_k127_7191325_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000001759 197.0
HFD2_k127_7197725_0 TIGRFAM type VI secretion protein IcmF K11891 - - 0.0 1077.0
HFD2_k127_7197725_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 8.748e-313 965.0
HFD2_k127_7197725_10 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 356.0
HFD2_k127_7197725_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000006335 236.0
HFD2_k127_7197725_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000001235 187.0
HFD2_k127_7197725_13 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.00000000000000000000000000000000000000000000008817 173.0
HFD2_k127_7197725_14 TIGRFAM type VI secretion-associated protein, BMA_A0400 family K11890 - - 0.0000000000000000000000000000000000000001462 161.0
HFD2_k127_7197725_15 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000954 149.0
HFD2_k127_7197725_16 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000246 93.0
HFD2_k127_7197725_17 - - - - 0.00001434 48.0
HFD2_k127_7197725_18 - - - - 0.0001351 46.0
HFD2_k127_7197725_2 Type II secretion system K02653 - - 2.149e-209 656.0
HFD2_k127_7197725_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 9.556e-196 614.0
HFD2_k127_7197725_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 612.0
HFD2_k127_7197725_5 Protein tyrosine kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 523.0
HFD2_k127_7197725_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 475.0
HFD2_k127_7197725_7 Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 485.0
HFD2_k127_7197725_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 447.0
HFD2_k127_7197725_9 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 413.0
HFD2_k127_7204594_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 3.191e-279 865.0
HFD2_k127_7204594_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 1.612e-207 651.0
HFD2_k127_7204594_2 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 555.0
HFD2_k127_7204594_3 Histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 481.0
HFD2_k127_7204594_4 RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 468.0
HFD2_k127_7204594_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 441.0
HFD2_k127_7204594_6 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 375.0
HFD2_k127_7204594_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
HFD2_k127_7204594_8 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001574 250.0
HFD2_k127_7204594_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009988 243.0
HFD2_k127_7241896_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.234e-241 748.0
HFD2_k127_7241896_1 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 349.0
HFD2_k127_7241896_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008257 248.0
HFD2_k127_7241896_3 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000275 98.0
HFD2_k127_7241896_4 Type II transport protein GspH K08084 - - 0.0000007855 53.0
HFD2_k127_7256298_0 Prolyl oligopeptidase family - - - 4.471e-267 859.0
HFD2_k127_7256298_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 594.0
HFD2_k127_7256298_10 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000001216 138.0
HFD2_k127_7256298_11 OmpA-like transmembrane domain K03286 - - 0.0000000000000000000000000003222 123.0
HFD2_k127_7256298_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 621.0
HFD2_k127_7256298_3 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 560.0
HFD2_k127_7256298_4 Luciferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 485.0
HFD2_k127_7256298_5 2OG-Fe dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 349.0
HFD2_k127_7256298_6 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001612 277.0
HFD2_k127_7256298_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002263 277.0
HFD2_k127_7256298_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000003762 226.0
HFD2_k127_7256298_9 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000001533 175.0
HFD2_k127_7279057_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1733.0
HFD2_k127_7279057_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 606.0
HFD2_k127_7279057_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 505.0
HFD2_k127_7279057_3 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 349.0
HFD2_k127_7279057_4 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 344.0
HFD2_k127_7279057_5 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
HFD2_k127_7279057_6 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000003537 174.0
HFD2_k127_7279057_7 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000002852 99.0
HFD2_k127_7279057_8 PFAM 4Fe-4S K00184,K21308 - - 0.0000001173 66.0
HFD2_k127_7279416_0 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 430.0
HFD2_k127_7279416_1 Alpha beta hydrolase K15923 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 370.0
HFD2_k127_7279416_2 methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000000008042 185.0
HFD2_k127_7279416_3 lipolytic protein G-D-S-L family - - - 0.00004955 49.0
HFD2_k127_7292684_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.626e-195 612.0
HFD2_k127_7292684_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 597.0
HFD2_k127_7292684_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 447.0
HFD2_k127_7292684_3 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 316.0
HFD2_k127_7311144_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1008.0
HFD2_k127_7311144_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 524.0
HFD2_k127_7311144_10 translation initiation factor activity K06996 - - 0.000000000000000000000246 101.0
HFD2_k127_7311144_11 Protein of unknown function (DUF3460) - - - 0.0000000000000000004355 101.0
HFD2_k127_7311144_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 527.0
HFD2_k127_7311144_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 451.0
HFD2_k127_7311144_4 Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 412.0
HFD2_k127_7311144_5 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 429.0
HFD2_k127_7311144_6 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 362.0
HFD2_k127_7311144_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006748 282.0
HFD2_k127_7311144_8 PFAM PRC-barrel domain protein - - - 0.0000000000000000000000000000000000000000000000006526 177.0
HFD2_k127_7311144_9 OsmC-like protein - - - 0.0000000000000000000000000000000000000000045 165.0
HFD2_k127_7324809_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.126e-238 757.0
HFD2_k127_7324809_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 609.0
HFD2_k127_7324809_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 606.0
HFD2_k127_7324809_3 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 573.0
HFD2_k127_7324809_4 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 407.0
HFD2_k127_7324809_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 346.0
HFD2_k127_7324809_6 PFAM regulatory protein TetR K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HFD2_k127_7324809_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000008409 93.0
HFD2_k127_7339006_0 PFAM Fibronectin type III domain protein K05973 - 3.1.1.75 6.589e-225 707.0
HFD2_k127_7339006_1 Extracellular ligand-binding receptor K01999 - - 7.332e-220 688.0
HFD2_k127_7339006_2 PFAM sigma-54 factor interaction domain-containing protein - - - 2.411e-200 632.0
HFD2_k127_7339006_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 526.0
HFD2_k127_7339006_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 493.0
HFD2_k127_7339006_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 466.0
HFD2_k127_7339006_6 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 381.0
HFD2_k127_7339006_7 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 374.0
HFD2_k127_7339006_8 lytic transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 338.0
HFD2_k127_7339006_9 Lipase (class 2) - - - 0.0000000000000000000000000000000000000000000000000000209 194.0
HFD2_k127_7348661_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 429.0
HFD2_k127_7348661_1 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 394.0
HFD2_k127_7348661_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 351.0
HFD2_k127_7348661_3 Sulphur oxidation protein SoxZ K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
HFD2_k127_7348661_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
HFD2_k127_7348661_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000105 259.0
HFD2_k127_7348661_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000002266 222.0
HFD2_k127_7348661_7 - - - - 0.00000000000000000000000000000000000000001577 155.0
HFD2_k127_7388614_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 653.0
HFD2_k127_7388614_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 566.0
HFD2_k127_7388614_10 Phytochelatin synthase - - - 0.0000000000000000000000000000000000000000000000000000000001148 220.0
HFD2_k127_7388614_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000003562 207.0
HFD2_k127_7388614_12 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000004346 206.0
HFD2_k127_7388614_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 509.0
HFD2_k127_7388614_3 Aldo/keto reductase family K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 490.0
HFD2_k127_7388614_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 436.0
HFD2_k127_7388614_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 402.0
HFD2_k127_7388614_6 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 396.0
HFD2_k127_7388614_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 352.0
HFD2_k127_7388614_8 FCD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 348.0
HFD2_k127_7388614_9 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000003519 263.0
HFD2_k127_7400024_0 PFAM major facilitator superfamily MFS_1 K08177 - - 2.185e-221 694.0
HFD2_k127_7400024_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 305.0
HFD2_k127_7400024_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000008958 224.0
HFD2_k127_7442537_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K05297 - 1.18.1.1,1.7.1.15 0.0 1062.0
HFD2_k127_7442537_1 protein phosphatase 2C domain protein K01090,K12132 - 2.7.11.1,3.1.3.16 1.994e-250 786.0
HFD2_k127_7442537_2 Major Facilitator Superfamily K02575 - - 2.068e-229 717.0
HFD2_k127_7442537_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 328.0
HFD2_k127_7442537_4 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 321.0
HFD2_k127_7442537_5 membrane transporter protein K07090 - - 0.0000001229 53.0
HFD2_k127_7472258_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261 - 1.4.1.2,1.4.1.3 4.618e-238 746.0
HFD2_k127_7472258_1 GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 365.0
HFD2_k127_7472258_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 358.0
HFD2_k127_7472258_3 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 355.0
HFD2_k127_7472258_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 346.0
HFD2_k127_7472258_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 325.0
HFD2_k127_7472258_6 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0000000000000000000000000000000000000000000000000000000000000004764 222.0
HFD2_k127_7472258_7 cyclic nucleotide binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000004474 219.0
HFD2_k127_7472258_8 PFAM superoxide dismutase, copper zinc binding K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000001912 195.0
HFD2_k127_7487313_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 502.0
HFD2_k127_7487313_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 346.0
HFD2_k127_7487313_2 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000001078 228.0
HFD2_k127_7487313_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000003654 189.0
HFD2_k127_7487313_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002701 195.0
HFD2_k127_7487313_5 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000002093 165.0
HFD2_k127_7487313_6 PAS fold - - - 0.0000000000000000000000000000007479 140.0
HFD2_k127_7507989_0 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 490.0
HFD2_k127_7507989_1 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 365.0
HFD2_k127_7507989_2 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 348.0
HFD2_k127_7507989_3 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000003349 195.0
HFD2_k127_7536379_0 Magnesium transport protein CorA - - - 1.221e-261 818.0
HFD2_k127_7536379_1 PFAM NUDIX hydrolase - - - 2.501e-200 638.0
HFD2_k127_7536379_2 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 297.0
HFD2_k127_7536379_3 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001885 273.0
HFD2_k127_7536379_4 PFAM 17 kDa surface antigen - - - 0.00000000000000000000000000000001903 131.0
HFD2_k127_7536379_5 belongs to the sigma-70 factor family - - - 0.00000000000000000003138 96.0
HFD2_k127_7536379_6 - - - - 0.00000000000468 70.0
HFD2_k127_7540612_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 1.547e-280 871.0
HFD2_k127_7540612_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 608.0
HFD2_k127_7540612_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
HFD2_k127_7552083_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 4e-323 1020.0
HFD2_k127_7552083_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 3.634e-209 653.0
HFD2_k127_7552083_10 spore germination - - - 0.000000000000000000000000000000000000000000000000000001393 203.0
HFD2_k127_7552083_11 cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000006364 130.0
HFD2_k127_7552083_2 AsmA family K07289 - - 2.019e-197 645.0
HFD2_k127_7552083_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 518.0
HFD2_k127_7552083_4 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 469.0
HFD2_k127_7552083_5 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 405.0
HFD2_k127_7552083_6 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
HFD2_k127_7552083_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 313.0
HFD2_k127_7552083_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 300.0
HFD2_k127_7552083_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001715 240.0
HFD2_k127_7595855_0 GTP-binding protein K06207 - - 0.0 1098.0
HFD2_k127_7595855_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 490.0
HFD2_k127_7595855_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 400.0
HFD2_k127_7595855_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 377.0
HFD2_k127_7595855_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 375.0
HFD2_k127_7595855_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 359.0
HFD2_k127_7595855_6 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 297.0
HFD2_k127_7595855_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000000005918 214.0
HFD2_k127_7595855_8 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000001646 126.0
HFD2_k127_7595855_9 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000006057 80.0
HFD2_k127_7630570_0 oxidoreductase K04090 - 1.2.7.8 0.0 1555.0
HFD2_k127_7655690_0 von Willebrand factor type A domain K07114 - - 3.993e-287 898.0
HFD2_k127_7655690_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 292.0
HFD2_k127_7655690_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 291.0
HFD2_k127_7655690_3 - - - - 0.000000000000000000000000000000000000000000000000000000000005148 212.0
HFD2_k127_7655690_4 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000000000000001886 202.0
HFD2_k127_7655690_6 - - - - 0.000000000000000004703 92.0
HFD2_k127_767861_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.672e-261 810.0
HFD2_k127_767861_1 Protein of unknown function (DUF1631) - - - 1.595e-209 684.0
HFD2_k127_767861_10 Protein of unknown function (DUF721) - - - 0.000000000000000000000000004073 113.0
HFD2_k127_767861_2 peptidase K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 439.0
HFD2_k127_767861_3 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 424.0
HFD2_k127_767861_4 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 398.0
HFD2_k127_767861_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 360.0
HFD2_k127_767861_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000000005718 236.0
HFD2_k127_767861_7 Starvation protein B K03600 - - 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
HFD2_k127_767861_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000001624 189.0
HFD2_k127_767861_9 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000001028 178.0
HFD2_k127_7736809_0 Alginate lyase - - - 1.041e-268 844.0
HFD2_k127_7736809_1 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 1.291e-212 673.0
HFD2_k127_7736809_2 PFAM glycosyl transferase family 2 K03669 - - 6.558e-196 651.0
HFD2_k127_7736809_3 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 567.0
HFD2_k127_7736809_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 370.0
HFD2_k127_7736809_5 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 273.0
HFD2_k127_7736809_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004411 271.0
HFD2_k127_7736809_7 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000006316 241.0
HFD2_k127_7770292_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.279e-224 705.0
HFD2_k127_7770292_1 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 3.519e-211 664.0
HFD2_k127_7770292_10 Glycine zipper 2TM domain K04062 - - 0.0000000000001477 76.0
HFD2_k127_7770292_2 Outer membrane protein beta-barrel family K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 593.0
HFD2_k127_7770292_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 492.0
HFD2_k127_7770292_4 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 448.0
HFD2_k127_7770292_5 Member of a two-component regulatory system K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 376.0
HFD2_k127_7770292_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 362.0
HFD2_k127_7770292_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
HFD2_k127_7770292_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000009402 138.0
HFD2_k127_7770292_9 - - - - 0.000000000000000000000000008776 117.0
HFD2_k127_7776797_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 465.0
HFD2_k127_7776797_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 384.0
HFD2_k127_7776797_2 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 370.0
HFD2_k127_7776797_3 regulatory - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 336.0
HFD2_k127_7776797_4 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 347.0
HFD2_k127_7776797_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 349.0
HFD2_k127_7776797_6 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001115 269.0
HFD2_k127_7776797_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
HFD2_k127_7776797_8 outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000000001002 188.0
HFD2_k127_7893427_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.131e-241 771.0
HFD2_k127_7893427_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.391e-223 696.0
HFD2_k127_7893427_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 7.728e-222 698.0
HFD2_k127_7893427_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 3.355e-198 639.0
HFD2_k127_7893427_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 548.0
HFD2_k127_7893427_5 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 356.0
HFD2_k127_7906501_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.101e-286 895.0
HFD2_k127_7906501_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 454.0
HFD2_k127_7906501_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
HFD2_k127_7906501_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000004069 199.0
HFD2_k127_7906501_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000001351 124.0
HFD2_k127_7906501_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000001344 110.0
HFD2_k127_7906501_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000001066 81.0
HFD2_k127_7906501_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000002613 61.0
HFD2_k127_7906501_8 Transcriptional regulator GntR family K03710 - - 0.0008146 43.0
HFD2_k127_7910974_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 4.783e-307 960.0
HFD2_k127_7910974_1 Phenol hydroxylase, C-terminal dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 578.0
HFD2_k127_7910974_2 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 476.0
HFD2_k127_7910974_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 310.0
HFD2_k127_7919911_0 Serine threonine protein kinase - - - 3.017e-203 634.0
HFD2_k127_7919911_1 Involved in the biosynthesis of porphyrin-containing compound - - - 3.731e-196 618.0
HFD2_k127_7919911_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000007953 133.0
HFD2_k127_7919911_2 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 526.0
HFD2_k127_7919911_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 510.0
HFD2_k127_7919911_4 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 409.0
HFD2_k127_7919911_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 402.0
HFD2_k127_7919911_6 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 390.0
HFD2_k127_7919911_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 344.0
HFD2_k127_7919911_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 310.0
HFD2_k127_7919911_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000002914 146.0
HFD2_k127_7925476_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1380.0
HFD2_k127_7925476_1 PFAM acyl-CoA dehydrogenase domain protein - - - 4.636e-208 649.0
HFD2_k127_7925476_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 543.0
HFD2_k127_7925476_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000000456 206.0
HFD2_k127_7939753_0 oxidoreductase FAD NAD(P)-binding domain protein K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 585.0
HFD2_k127_7939753_1 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 466.0
HFD2_k127_7939753_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 461.0
HFD2_k127_7939753_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 416.0
HFD2_k127_7939753_4 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 427.0
HFD2_k127_7939753_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 361.0
HFD2_k127_7939753_6 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 281.0
HFD2_k127_7939753_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00001349 52.0
HFD2_k127_7945426_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.526e-264 823.0
HFD2_k127_7945426_1 Belongs to the thiolase family K00626 - 2.3.1.9 9.013e-212 673.0
HFD2_k127_7945426_10 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
HFD2_k127_7945426_11 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000006196 246.0
HFD2_k127_7945426_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000002423 183.0
HFD2_k127_7945426_13 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000877 171.0
HFD2_k127_7945426_14 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000000000000000000000002291 139.0
HFD2_k127_7945426_15 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000000001308 121.0
HFD2_k127_7945426_16 CsbD-like - - - 0.00000000000000000000000000004257 119.0
HFD2_k127_7945426_17 PFAM transglutaminase domain protein - - - 0.00000000000000000000001044 102.0
HFD2_k127_7945426_18 - - - - 0.000000000000000000004336 97.0
HFD2_k127_7945426_19 Protein of unknown function (DUF1328) - - - 0.000000000000000008376 83.0
HFD2_k127_7945426_2 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 621.0
HFD2_k127_7945426_20 - - - - 0.00000000000000002559 85.0
HFD2_k127_7945426_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 448.0
HFD2_k127_7945426_4 CHASE3 domain K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 434.0
HFD2_k127_7945426_5 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 386.0
HFD2_k127_7945426_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 362.0
HFD2_k127_7945426_7 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
HFD2_k127_7945426_8 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
HFD2_k127_7945426_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 299.0
HFD2_k127_7968008_0 PFAM CoA-binding domain protein K09181 - - 0.0 1187.0
HFD2_k127_7968008_1 Anion-transporting ATPase K01551 - 3.6.3.16 7.265e-241 762.0
HFD2_k127_7968008_10 Transcriptional regulator K03892 - - 0.0000000000000000000000000000000000000000000001872 169.0
HFD2_k127_7968008_11 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.000000000000000000003746 109.0
HFD2_k127_7968008_12 DNA-binding transcription factor activity - - - 0.00000000000001303 83.0
HFD2_k127_7968008_2 FtsX-like permease family K02004 - - 6.444e-207 666.0
HFD2_k127_7968008_3 Sodium Bile acid symporter family K03325 - - 3.854e-194 611.0
HFD2_k127_7968008_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 522.0
HFD2_k127_7968008_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 512.0
HFD2_k127_7968008_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 362.0
HFD2_k127_7968008_7 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 301.0
HFD2_k127_7968008_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 285.0
HFD2_k127_7968008_9 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000004332 192.0
HFD2_k127_7978055_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0 1078.0
HFD2_k127_7978055_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 7.831e-218 683.0
HFD2_k127_7978055_2 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 522.0
HFD2_k127_7978055_3 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
HFD2_k127_7978055_4 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000007477 167.0
HFD2_k127_7978055_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000001136 79.0
HFD2_k127_79981_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1256.0
HFD2_k127_79981_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.163e-245 787.0
HFD2_k127_79981_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 412.0
HFD2_k127_79981_11 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 444.0
HFD2_k127_79981_12 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 328.0
HFD2_k127_79981_13 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007021 293.0
HFD2_k127_79981_14 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
HFD2_k127_79981_15 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000865 279.0
HFD2_k127_79981_16 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001991 261.0
HFD2_k127_79981_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000003888 194.0
HFD2_k127_79981_18 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000005676 190.0
HFD2_k127_79981_19 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000000007658 160.0
HFD2_k127_79981_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.811e-233 743.0
HFD2_k127_79981_20 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000000001847 157.0
HFD2_k127_79981_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.979e-221 698.0
HFD2_k127_79981_4 acetylornithine K00821 - 2.6.1.11,2.6.1.17 3.326e-219 688.0
HFD2_k127_79981_5 Belongs to the universal stress protein A family - - - 2.131e-210 664.0
HFD2_k127_79981_6 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 600.0
HFD2_k127_79981_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 592.0
HFD2_k127_79981_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 579.0
HFD2_k127_79981_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 432.0
HFD2_k127_8013126_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 571.0
HFD2_k127_8013126_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 501.0
HFD2_k127_8013126_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 477.0
HFD2_k127_8013126_3 Male sterility protein K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 425.0
HFD2_k127_8013126_4 regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 311.0
HFD2_k127_8013126_5 TRAP dicarboxylate transporter K21395 - - 0.00000000000000000001438 93.0
HFD2_k127_8029418_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1184.0
HFD2_k127_8029418_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.369e-240 747.0
HFD2_k127_8029418_10 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000746 197.0
HFD2_k127_8029418_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000000002832 143.0
HFD2_k127_8029418_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000003197 93.0
HFD2_k127_8029418_13 - - - - 0.0000000000000003651 92.0
HFD2_k127_8029418_2 Polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 1.251e-233 728.0
HFD2_k127_8029418_3 PFAM aminotransferase, class I and II K00832 - 2.6.1.57 1.964e-199 627.0
HFD2_k127_8029418_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 370.0
HFD2_k127_8029418_5 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 333.0
HFD2_k127_8029418_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 333.0
HFD2_k127_8029418_7 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 316.0
HFD2_k127_8029418_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003015 244.0
HFD2_k127_8029418_9 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
HFD2_k127_8029474_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.59e-227 715.0
HFD2_k127_8029474_1 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
HFD2_k127_8029474_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 378.0
HFD2_k127_8029474_3 Rod shape-determining protein mreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009205 277.0
HFD2_k127_8030995_0 Dyp-type peroxidase family - - - 3.768e-248 807.0
HFD2_k127_8030995_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 604.0
HFD2_k127_8030995_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 492.0
HFD2_k127_8030995_3 Pectate lyase K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 338.0
HFD2_k127_8030995_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000132 217.0
HFD2_k127_8030995_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000001082 113.0
HFD2_k127_8052977_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.988e-245 778.0
HFD2_k127_8052977_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 1.1e-234 739.0
HFD2_k127_8052977_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000007523 148.0
HFD2_k127_8052977_2 Belongs to the ABC transporter superfamily K17325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 549.0
HFD2_k127_8052977_3 Belongs to the ABC transporter superfamily K17324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 545.0
HFD2_k127_8052977_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 533.0
HFD2_k127_8052977_5 PFAM binding-protein-dependent transport systems inner membrane component K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 527.0
HFD2_k127_8052977_6 binding-protein-dependent transport systems inner membrane component K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 497.0
HFD2_k127_8052977_7 PFAM regulatory protein DeoR K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 425.0
HFD2_k127_8052977_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
HFD2_k127_8052977_9 Helix-turn-helix type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 299.0
HFD2_k127_8068674_0 Zinc metalloprotease (Elastase) - - - 0.0 1059.0
HFD2_k127_8068674_1 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 3.85e-220 684.0
HFD2_k127_8068674_2 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 290.0
HFD2_k127_8068674_3 PQQ-like domain - - - 0.00000000000000000001671 103.0
HFD2_k127_8068674_4 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000000000003572 96.0
HFD2_k127_8068674_5 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000001281 89.0
HFD2_k127_8089646_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 1.818e-195 622.0
HFD2_k127_8089646_1 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 410.0
HFD2_k127_8089646_2 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
HFD2_k127_8089646_3 COG1132 ABC-type multidrug transport system, ATPase and permease components K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006268 238.0
HFD2_k127_8089646_4 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000001269 225.0
HFD2_k127_8089646_5 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000005097 207.0
HFD2_k127_8089646_6 NmrA-like family - - - 0.0000000000000000000000000000008648 131.0
HFD2_k127_8089646_7 TIR domain - - - 0.0000000000000000000001815 112.0
HFD2_k127_8089646_8 - - - - 0.000000000000000000005639 94.0
HFD2_k127_8089646_9 peptidyl-tyrosine sulfation - - - 0.0000000002712 73.0
HFD2_k127_8101587_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 2.836e-206 651.0
HFD2_k127_8101587_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 537.0
HFD2_k127_8101587_10 - - - - 0.0000000000003264 80.0
HFD2_k127_8101587_2 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 287.0
HFD2_k127_8101587_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001377 255.0
HFD2_k127_8101587_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003794 259.0
HFD2_k127_8101587_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000002968 130.0
HFD2_k127_8101587_6 Dodecin K09165 - - 0.000000000000000000000000000000003534 132.0
HFD2_k127_8101587_7 Peptidase S24-like - - - 0.00000000000000000000000000000006786 136.0
HFD2_k127_8101587_8 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000006897 113.0
HFD2_k127_8101587_9 - - - - 0.0000000000000007428 84.0
HFD2_k127_8103834_0 Amidase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 480.0
HFD2_k127_8103834_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 438.0
HFD2_k127_8103834_2 RES domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 249.0
HFD2_k127_8103834_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000005884 133.0
HFD2_k127_8103834_4 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000003875 139.0
HFD2_k127_8130193_0 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 492.0
HFD2_k127_8130193_1 Protein of unknown function (DUF2167) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 377.0
HFD2_k127_8130193_2 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 371.0
HFD2_k127_8130193_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 290.0
HFD2_k127_8130193_4 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000000000004645 231.0
HFD2_k127_8130193_5 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000004596 171.0
HFD2_k127_8130193_6 import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000001787 115.0
HFD2_k127_8132784_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2147.0
HFD2_k127_8132784_1 Di-haem cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 1.189e-207 689.0
HFD2_k127_8138602_0 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 569.0
HFD2_k127_8138602_1 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 520.0
HFD2_k127_8138602_2 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 511.0
HFD2_k127_8138602_3 UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 450.0
HFD2_k127_8138602_4 ATPases associated with a variety of cellular activities K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 448.0
HFD2_k127_8138602_5 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
HFD2_k127_8138602_6 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.0000000000000000000000000000000000000000000000000002953 201.0
HFD2_k127_8145838_0 TIGRFAM type I secretion system ATPase K12541 - - 0.0 1028.0
HFD2_k127_8145838_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 622.0
HFD2_k127_8145838_2 TIGRFAM outer membrane adhesin like proteiin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003142 267.0
HFD2_k127_8145838_3 TIGRFAM outer membrane adhesin like proteiin - - - 0.00000000000001078 88.0
HFD2_k127_8148192_0 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate K11103 - - 5.149e-240 749.0
HFD2_k127_8148192_1 Glucose / Sorbosone dehydrogenase - - - 2.808e-228 713.0
HFD2_k127_8148192_10 Lysine methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009976 296.0
HFD2_k127_8148192_11 - - - - 0.000000000000000000000000000000000000000000000000000001771 193.0
HFD2_k127_8148192_12 Gluconokinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000776 188.0
HFD2_k127_8148192_13 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000006879 100.0
HFD2_k127_8148192_2 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 576.0
HFD2_k127_8148192_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 572.0
HFD2_k127_8148192_4 FAD-NAD(P)-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 554.0
HFD2_k127_8148192_5 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 501.0
HFD2_k127_8148192_6 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 379.0
HFD2_k127_8148192_7 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 370.0
HFD2_k127_8148192_8 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 376.0
HFD2_k127_8148192_9 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 375.0
HFD2_k127_8159073_0 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 6.811e-274 850.0
HFD2_k127_8159073_1 Transmembrane secretion effector - - - 2.94e-237 743.0
HFD2_k127_8159073_2 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 539.0
HFD2_k127_8159073_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 444.0
HFD2_k127_8159073_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 444.0
HFD2_k127_8159073_5 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 435.0
HFD2_k127_8159073_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000001738 92.0
HFD2_k127_8188879_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 4.458e-227 719.0
HFD2_k127_8188879_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 5.74e-199 624.0
HFD2_k127_8188879_2 lytic transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 618.0
HFD2_k127_8188879_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
HFD2_k127_8188879_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
HFD2_k127_8188879_5 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 288.0
HFD2_k127_8188879_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000003105 189.0
HFD2_k127_8188879_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000003352 106.0
HFD2_k127_8208659_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.488e-215 674.0
HFD2_k127_8208659_1 Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
HFD2_k127_8208659_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001703 269.0
HFD2_k127_8208659_3 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002343 264.0
HFD2_k127_8208659_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000005101 241.0
HFD2_k127_8208659_5 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000001826 186.0
HFD2_k127_8208659_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.000000000000000000008557 92.0
HFD2_k127_8222940_0 Belongs to the glutamate synthase family - - - 2.019e-280 893.0
HFD2_k127_8222940_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 502.0
HFD2_k127_8222940_10 response regulator - - - 0.00000000000000000003469 107.0
HFD2_k127_8222940_2 Alpha beta hydrolase K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 442.0
HFD2_k127_8222940_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 420.0
HFD2_k127_8222940_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 343.0
HFD2_k127_8222940_5 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 337.0
HFD2_k127_8222940_6 Secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004012 277.0
HFD2_k127_8222940_7 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000194 267.0
HFD2_k127_8222940_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002611 140.0
HFD2_k127_8222940_9 peptidase M48, Ste24p - - - 0.000000000000000000000000000000003035 134.0
HFD2_k127_8228756_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 544.0
HFD2_k127_8228756_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 519.0
HFD2_k127_8228756_2 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 347.0
HFD2_k127_8228756_3 phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 304.0
HFD2_k127_8228756_4 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
HFD2_k127_8233834_0 JmjC domain, hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 516.0
HFD2_k127_8233834_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 360.0
HFD2_k127_8233834_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 361.0
HFD2_k127_8233834_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 303.0
HFD2_k127_8233834_4 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
HFD2_k127_8268537_0 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 348.0
HFD2_k127_8268537_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 320.0
HFD2_k127_8268537_2 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
HFD2_k127_8268537_3 Hemolysin III K11068 - - 0.00000000000000000000000000000000000000000000000000000000007773 215.0
HFD2_k127_8268537_4 - - - - 0.00000000000000007963 83.0
HFD2_k127_8278450_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1043.0
HFD2_k127_8278450_1 PQQ-like domain - - - 3.012e-306 970.0
HFD2_k127_8278450_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000003545 145.0
HFD2_k127_8278450_11 - - - - 0.000000000000000000000000000000002809 148.0
HFD2_k127_8278450_2 PFAM acyl-CoA dehydrogenase domain protein - - - 3.505e-223 697.0
HFD2_k127_8278450_3 Lipase (class 2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 578.0
HFD2_k127_8278450_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 538.0
HFD2_k127_8278450_5 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 537.0
HFD2_k127_8278450_6 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 420.0
HFD2_k127_8278450_7 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 423.0
HFD2_k127_8278450_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 393.0
HFD2_k127_8278450_9 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 359.0
HFD2_k127_8279303_0 Long-chain fatty acid--CoA ligase K00666,K01897 - 6.2.1.3 5.853e-198 627.0
HFD2_k127_8279303_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 451.0
HFD2_k127_8279303_2 Protein kinase domain K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 388.0
HFD2_k127_8279303_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 331.0
HFD2_k127_8279303_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.000000000000000000000000000000000000000000000001271 196.0
HFD2_k127_8280270_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1155.0
HFD2_k127_8280270_1 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 3.253e-201 634.0
HFD2_k127_8280270_2 PFAM regulatory protein TetR K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 285.0
HFD2_k127_8280270_3 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
HFD2_k127_8280270_4 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000006454 209.0
HFD2_k127_8280270_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.000000000000000000000000000000000000008512 149.0
HFD2_k127_8306660_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 594.0
HFD2_k127_8306660_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 415.0
HFD2_k127_8306660_2 belongs to the aldehyde dehydrogenase family K00130,K00146 - 1.2.1.39,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 379.0
HFD2_k127_8306660_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 394.0
HFD2_k127_8306660_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001231 271.0
HFD2_k127_8306660_5 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000003615 145.0
HFD2_k127_8319049_0 Major royal jelly protein - - - 6.448e-227 724.0
HFD2_k127_8319049_1 Trap dicarboxylate transporter, dctm subunit - - - 2.429e-213 670.0
HFD2_k127_8319049_10 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
HFD2_k127_8319049_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000005488 220.0
HFD2_k127_8319049_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.795e-213 668.0
HFD2_k127_8319049_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 542.0
HFD2_k127_8319049_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 485.0
HFD2_k127_8319049_5 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 403.0
HFD2_k127_8319049_6 KR domain K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 377.0
HFD2_k127_8319049_7 Pfam:Methyltransf_6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 350.0
HFD2_k127_8319049_8 PFAM Cupin 2, conserved barrel domain protein K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 338.0
HFD2_k127_8319049_9 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005555 281.0
HFD2_k127_8328982_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 512.0
HFD2_k127_8328982_1 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
HFD2_k127_8328982_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007419 247.0
HFD2_k127_8328982_3 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000001302 228.0
HFD2_k127_8328982_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
HFD2_k127_8328982_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000001432 129.0
HFD2_k127_8348442_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1518.0
HFD2_k127_8348442_1 Helicase K03657 - 3.6.4.12 0.0 1253.0
HFD2_k127_8348442_10 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 388.0
HFD2_k127_8348442_11 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 348.0
HFD2_k127_8348442_12 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
HFD2_k127_8348442_13 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
HFD2_k127_8348442_14 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 306.0
HFD2_k127_8348442_15 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
HFD2_k127_8348442_16 Nudix N-terminal K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
HFD2_k127_8348442_17 PFAM response regulator receiver K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
HFD2_k127_8348442_18 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
HFD2_k127_8348442_19 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000000001078 216.0
HFD2_k127_8348442_2 Major facilitator Superfamily - - - 7.921e-196 628.0
HFD2_k127_8348442_20 Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP) K00846,K18478 - 2.7.1.184,2.7.1.3 0.000000000000000000000000000000000000000000000000004587 194.0
HFD2_k127_8348442_21 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000001785 197.0
HFD2_k127_8348442_22 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000002998 179.0
HFD2_k127_8348442_23 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000003884 136.0
HFD2_k127_8348442_24 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000003524 123.0
HFD2_k127_8348442_25 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000007569 83.0
HFD2_k127_8348442_26 Hemerythrin HHE cation binding domain protein - - - 0.0000003706 56.0
HFD2_k127_8348442_3 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 566.0
HFD2_k127_8348442_4 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 565.0
HFD2_k127_8348442_5 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 544.0
HFD2_k127_8348442_6 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 541.0
HFD2_k127_8348442_7 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 480.0
HFD2_k127_8348442_8 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 470.0
HFD2_k127_8348442_9 glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 431.0
HFD2_k127_8355983_0 ammonium transporter K03320 - - 1.036e-234 729.0
HFD2_k127_8355983_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 526.0
HFD2_k127_8355983_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000002402 180.0
HFD2_k127_8362262_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.47e-222 694.0
HFD2_k127_8362262_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 538.0
HFD2_k127_8362262_2 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 507.0
HFD2_k127_8362262_3 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002618 280.0
HFD2_k127_8362513_0 molybdopterin K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 560.0
HFD2_k127_8362513_1 Formate dehydrogenase gamma subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 513.0
HFD2_k127_8362513_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 468.0
HFD2_k127_8362513_3 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000005185 231.0
HFD2_k127_8362513_4 - - - - 0.00000000000000000000000000002085 124.0
HFD2_k127_8362513_5 - - - - 0.0000000003455 64.0
HFD2_k127_8362513_6 PFAM binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.000000001202 65.0
HFD2_k127_8376811_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1190.0
HFD2_k127_8376811_1 type II and III secretion system protein K02666 - - 4.4e-323 1013.0
HFD2_k127_8376811_10 Belongs to the frataxin family K06202 - - 0.000000000000000000000000000000000000000000002106 176.0
HFD2_k127_8376811_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000005188 54.0
HFD2_k127_8376811_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.277e-212 670.0
HFD2_k127_8376811_3 pilus assembly protein PilM K02662 - - 1.854e-204 640.0
HFD2_k127_8376811_4 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 561.0
HFD2_k127_8376811_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 346.0
HFD2_k127_8376811_6 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
HFD2_k127_8376811_7 Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005669 272.0
HFD2_k127_8376811_8 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
HFD2_k127_8376811_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000006282 254.0
HFD2_k127_8400573_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 567.0
HFD2_k127_8400573_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 458.0
HFD2_k127_8400573_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 402.0
HFD2_k127_8400573_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 384.0
HFD2_k127_8400573_4 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 339.0
HFD2_k127_8400573_5 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 326.0
HFD2_k127_8400573_6 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001776 290.0
HFD2_k127_8400573_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000002319 87.0
HFD2_k127_8401329_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0 1047.0
HFD2_k127_8401329_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 477.0
HFD2_k127_8401329_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 460.0
HFD2_k127_8401329_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
HFD2_k127_8401329_4 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002202 244.0
HFD2_k127_8401329_5 ATPases associated with a variety of cellular activities K05779 - - 0.0000000005485 61.0
HFD2_k127_84018_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.19e-321 987.0
HFD2_k127_84018_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.757e-308 945.0
HFD2_k127_84018_2 ATP-binding region, ATPase domain protein - - - 1.106e-287 902.0
HFD2_k127_84018_3 Oxidoreductase NAD-binding domain K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 3.555e-227 758.0
HFD2_k127_84018_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 2.768e-221 717.0
HFD2_k127_84018_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 376.0
HFD2_k127_84018_6 Transcriptional regulator crp fnr family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 338.0
HFD2_k127_84018_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K00926 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 0.0000000000000000000002826 103.0
HFD2_k127_8405351_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1390.0
HFD2_k127_8405351_1 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 601.0
HFD2_k127_8405351_10 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003208 272.0
HFD2_k127_8405351_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001209 248.0
HFD2_k127_8405351_12 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000001368 205.0
HFD2_k127_8405351_13 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000003789 196.0
HFD2_k127_8405351_14 Sulphur transport K07112 - - 0.0000000000000000000000000000000000003768 161.0
HFD2_k127_8405351_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 582.0
HFD2_k127_8405351_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 439.0
HFD2_k127_8405351_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 419.0
HFD2_k127_8405351_5 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 416.0
HFD2_k127_8405351_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 405.0
HFD2_k127_8405351_7 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 345.0
HFD2_k127_8405351_8 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 332.0
HFD2_k127_8405351_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001227 265.0
HFD2_k127_8450220_0 type VI secretion protein K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 551.0
HFD2_k127_8450220_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
HFD2_k127_8450220_2 Domain of unknown function (DUF4280) - - - 0.0000000000000000000000000000000000000000000000000000187 191.0
HFD2_k127_8450220_3 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.00000000000000000000000000000000000007116 147.0
HFD2_k127_8450220_4 Belongs to the ompA family - - - 0.0000000000008177 78.0
HFD2_k127_8475114_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 5.931e-231 721.0
HFD2_k127_8475114_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 529.0
HFD2_k127_8475114_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 467.0
HFD2_k127_8475114_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 325.0
HFD2_k127_8475114_4 PFAM UspA domain protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001338 263.0
HFD2_k127_8475114_5 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
HFD2_k127_8475114_6 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000001107 168.0
HFD2_k127_8475114_7 - - - - 0.00000000000000000000000000000000005585 151.0
HFD2_k127_8479801_0 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 491.0
HFD2_k127_8479801_1 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 384.0
HFD2_k127_8479801_2 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19743 - 1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 342.0
HFD2_k127_8479801_3 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
HFD2_k127_8479801_4 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000001755 233.0
HFD2_k127_8479801_5 - - - - 0.0000000000000000000000000000000000000000000000000000001944 208.0
HFD2_k127_8479801_6 BON domain - - - 0.0000000000000000000000000000000000000000001153 182.0
HFD2_k127_8479801_7 - - - - 0.00000000000000000000000000005095 126.0
HFD2_k127_8479801_9 Protein of unknown function (DUF3365) - - - 0.0000005457 61.0
HFD2_k127_8505197_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1120.0
HFD2_k127_8505197_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 609.0
HFD2_k127_8505197_10 Ribosome-associated heat shock protein K04762 - - 0.0000000000000000000000000000000000000000000008767 184.0
HFD2_k127_8505197_11 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000009202 58.0
HFD2_k127_8505197_2 PFAM conserved K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 539.0
HFD2_k127_8505197_3 Transcriptional regulatory protein, C terminal K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 341.0
HFD2_k127_8505197_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002794 245.0
HFD2_k127_8505197_5 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000008546 237.0
HFD2_k127_8505197_6 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
HFD2_k127_8505197_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000001229 236.0
HFD2_k127_8505197_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000016 201.0
HFD2_k127_8505197_9 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.000000000000000000000000000000000000000000000000000001778 203.0
HFD2_k127_8551503_0 Radical SAM - - - 6.686e-216 674.0
HFD2_k127_8551503_1 Cytochrome D1 heme domain K19345 - - 2.686e-204 647.0
HFD2_k127_8551503_2 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 592.0
HFD2_k127_8551503_3 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 424.0
HFD2_k127_8551503_4 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000147 273.0
HFD2_k127_8551503_5 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
HFD2_k127_8551503_6 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000000000000000003252 154.0
HFD2_k127_8551503_7 Cytochrome c K08738 - - 0.00000000000000000000000000000000000001842 145.0
HFD2_k127_8551503_8 Cytochrome D1 heme domain - - - 0.000000000000000000000003116 107.0
HFD2_k127_8583643_0 Aldehyde dehydrogenase family - - - 1.516e-219 710.0
HFD2_k127_8583643_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 580.0
HFD2_k127_8583643_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 328.0
HFD2_k127_8583643_3 Transcriptional regulator K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 341.0
HFD2_k127_8583643_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 320.0
HFD2_k127_8583643_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000006664 228.0
HFD2_k127_8583643_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000003883 113.0
HFD2_k127_8591677_0 twitching motility protein K02670 - - 5.164e-221 691.0
HFD2_k127_8591677_1 PFAM Type II secretion system protein E K02669,K12203 - - 1.218e-206 659.0
HFD2_k127_8591677_2 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 408.0
HFD2_k127_8591677_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 322.0
HFD2_k127_8591677_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 318.0
HFD2_k127_8591677_5 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001774 268.0
HFD2_k127_8591677_6 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007102 254.0
HFD2_k127_8591677_7 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000003779 156.0
HFD2_k127_8612943_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.318e-257 802.0
HFD2_k127_8612943_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 629.0
HFD2_k127_8612943_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 502.0
HFD2_k127_8612943_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
HFD2_k127_8612943_4 STAS-like domain of unknown function (DUF4325) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007469 254.0
HFD2_k127_8612943_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000001169 94.0
HFD2_k127_8627758_0 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 449.0
HFD2_k127_8627758_1 KR domain K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 431.0
HFD2_k127_8627758_2 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008424 243.0
HFD2_k127_8627758_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000002362 239.0
HFD2_k127_8646977_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.279e-221 694.0
HFD2_k127_8646977_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 2.35e-206 655.0
HFD2_k127_8646977_10 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004888 261.0
HFD2_k127_8646977_11 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.000000000000000000000000000000000000000000007812 164.0
HFD2_k127_8646977_2 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 6.349e-203 640.0
HFD2_k127_8646977_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 550.0
HFD2_k127_8646977_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 538.0
HFD2_k127_8646977_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 504.0
HFD2_k127_8646977_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 469.0
HFD2_k127_8646977_7 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 405.0
HFD2_k127_8646977_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
HFD2_k127_8646977_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006568 268.0
HFD2_k127_8673539_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1120.0
HFD2_k127_8673539_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.422e-270 838.0
HFD2_k127_8673539_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 546.0
HFD2_k127_8719507_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1551.0
HFD2_k127_8719507_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 332.0
HFD2_k127_8719507_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000004674 183.0
HFD2_k127_8719507_3 SpoVT / AbrB like domain - - - 0.000000000000000000000000000000000000001343 148.0
HFD2_k127_8719507_4 Signal peptide protein - - - 0.000000001966 58.0
HFD2_k127_87444_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 4.883e-244 759.0
HFD2_k127_87444_1 Peptidase M48 K06013 - 3.4.24.84 6.178e-201 635.0
HFD2_k127_87444_10 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000000000001731 254.0
HFD2_k127_87444_11 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HFD2_k127_87444_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008896 252.0
HFD2_k127_87444_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000001939 215.0
HFD2_k127_87444_14 TM2 domain - - - 0.00000000000000000000000000000000000000000000000000000000005584 207.0
HFD2_k127_87444_15 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000001391 204.0
HFD2_k127_87444_16 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000005553 142.0
HFD2_k127_87444_17 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000005708 62.0
HFD2_k127_87444_18 Putative member of DMT superfamily (DUF486) K09922 - - 0.0002758 45.0
HFD2_k127_87444_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 580.0
HFD2_k127_87444_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 508.0
HFD2_k127_87444_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 465.0
HFD2_k127_87444_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 424.0
HFD2_k127_87444_6 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 374.0
HFD2_k127_87444_7 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 345.0
HFD2_k127_87444_8 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
HFD2_k127_87444_9 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HFD2_k127_893043_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 2.848e-242 784.0
HFD2_k127_893043_1 histidine kinase HAMP region domain protein - - - 5.154e-205 661.0
HFD2_k127_893043_10 TIGRFAM pentapeptide MXKDX repeat protein - - - 0.00000000000000002006 87.0
HFD2_k127_893043_2 mandelate racemase muconate lactonizing K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 529.0
HFD2_k127_893043_3 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 507.0
HFD2_k127_893043_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 432.0
HFD2_k127_893043_5 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 416.0
HFD2_k127_893043_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 341.0
HFD2_k127_893043_7 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004095 273.0
HFD2_k127_893043_8 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000006136 256.0
HFD2_k127_893043_9 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002352 254.0
HFD2_k127_8947_0 Periplasmic binding protein LacI transcriptional regulator K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 535.0
HFD2_k127_8947_1 Short-chain dehydrogenase reductase sdr K22185 - 1.1.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 376.0
HFD2_k127_8947_2 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 315.0
HFD2_k127_8947_3 Periplasmic binding protein domain K10543,K10546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 315.0
HFD2_k127_900261_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 1.539e-315 975.0
HFD2_k127_900261_1 Receptor - - - 6.065e-314 983.0
HFD2_k127_900261_10 - - - - 0.0000000000000000000002352 102.0
HFD2_k127_900261_2 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 1.367e-208 659.0
HFD2_k127_900261_3 Histidine kinase - - - 5.573e-204 676.0
HFD2_k127_900261_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 620.0
HFD2_k127_900261_5 Von willebrand factor, type a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 445.0
HFD2_k127_900261_6 overlaps another CDS with the same product name K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 447.0
HFD2_k127_900261_7 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005463 258.0
HFD2_k127_900261_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000005211 248.0
HFD2_k127_900261_9 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001299 218.0
HFD2_k127_923343_0 binding-protein-dependent transport systems inner membrane component K02011 - - 8.92e-265 826.0
HFD2_k127_923343_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.317e-240 745.0
HFD2_k127_923343_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 576.0
HFD2_k127_934149_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 2.183e-208 664.0
HFD2_k127_934149_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 512.0
HFD2_k127_934149_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 334.0
HFD2_k127_934149_3 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000000000005656 239.0
HFD2_k127_934149_4 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000005284 190.0
HFD2_k127_934149_5 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000002367 70.0
HFD2_k127_935278_0 SpoVR like protein K06415 - - 3.089e-295 930.0
HFD2_k127_935278_1 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 4.41e-238 743.0
HFD2_k127_935278_2 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 602.0
HFD2_k127_935278_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 336.0
HFD2_k127_935278_4 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 308.0
HFD2_k127_942921_0 histidine kinase A domain protein - - - 0.0 1499.0
HFD2_k127_942921_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1016.0
HFD2_k127_942921_10 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000001359 175.0
HFD2_k127_942921_11 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000001299 186.0
HFD2_k127_942921_12 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000004596 73.0
HFD2_k127_942921_2 Urea ABC transporter, urea binding protein K11959 - - 1.417e-253 785.0
HFD2_k127_942921_3 Belongs to the binding-protein-dependent transport system permease family K11960 - - 1.086e-222 702.0
HFD2_k127_942921_4 CoA-transferase family III - - - 1.335e-202 653.0
HFD2_k127_942921_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 482.0
HFD2_k127_942921_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 452.0
HFD2_k127_942921_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 443.0
HFD2_k127_942921_8 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 335.0
HFD2_k127_942921_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001275 286.0
HFD2_k127_949512_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1053.0
HFD2_k127_949512_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.26e-240 750.0
HFD2_k127_949512_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 594.0
HFD2_k127_949512_3 Histidine kinase K11711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 555.0
HFD2_k127_949512_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 465.0
HFD2_k127_949512_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 454.0
HFD2_k127_949512_6 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 396.0
HFD2_k127_949512_7 2Fe-2S -binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
HFD2_k127_949512_8 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000006226 177.0
HFD2_k127_953079_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 1.134e-246 799.0
HFD2_k127_953079_1 Extracellular solute-binding protein K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 606.0
HFD2_k127_953079_10 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006176 237.0
HFD2_k127_953079_11 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001766 229.0
HFD2_k127_953079_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 490.0
HFD2_k127_953079_3 transport K02025,K10237,K17245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 432.0
HFD2_k127_953079_4 Pfam Binding-protein-dependent transport systems inner membrane component K02026,K10238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 377.0
HFD2_k127_953079_5 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
HFD2_k127_953079_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
HFD2_k127_953079_7 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
HFD2_k127_953079_8 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 282.0
HFD2_k127_953079_9 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 249.0
HFD2_k127_99678_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 582.0
HFD2_k127_99678_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 442.0
HFD2_k127_99678_10 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000005924 61.0
HFD2_k127_99678_11 - - - - 0.000001464 61.0
HFD2_k127_99678_2 PFAM AsmA family protein K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 449.0
HFD2_k127_99678_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 440.0
HFD2_k127_99678_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 393.0
HFD2_k127_99678_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 410.0
HFD2_k127_99678_6 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000009191 162.0
HFD2_k127_99678_7 PFAM Lipocalin family protein K03098 - - 0.00000000000000000000000000000000000004777 159.0
HFD2_k127_99678_8 SMART Transport-associated and nodulation region K04065 - - 0.000000000000000000000000000000002311 143.0