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Overview

ID MAG01676
Name HFD3_bin.13
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order UBA9968
Family UBA9968
Genus JACPFE01
Species
Assembly information
Completeness (%) 90.95
Contamination (%) 2.86
GC content (%) 57.0
N50 (bp) 13,090
Genome size (bp) 5,187,452

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4645

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1011659_0 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 362.0
HFD3_k127_1011659_1 ABC-type multidrug transport system ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 341.0
HFD3_k127_1011659_2 PFAM MltA domain protein K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 309.0
HFD3_k127_1011659_3 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001316 277.0
HFD3_k127_1011659_4 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001812 261.0
HFD3_k127_1011659_5 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
HFD3_k127_1011659_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000007059 191.0
HFD3_k127_1011659_7 Zincin-like metallopeptidase - - - 0.0000000000000051 78.0
HFD3_k127_1011659_8 Domain of Unknown Function (DUF748) - - - 0.00000001974 58.0
HFD3_k127_1042230_0 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HFD3_k127_1042230_1 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001081 261.0
HFD3_k127_1042230_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000008276 198.0
HFD3_k127_1042230_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000004638 184.0
HFD3_k127_1042230_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000000000000000000005529 116.0
HFD3_k127_1042230_5 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate K01612,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.000000000000000000000000884 108.0
HFD3_k127_1042230_6 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000007216 100.0
HFD3_k127_1042230_7 NMT1-like family K02051 - - 0.0000000000000000147 94.0
HFD3_k127_1042230_8 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000005991 66.0
HFD3_k127_104555_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 356.0
HFD3_k127_104555_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000004901 170.0
HFD3_k127_104555_2 NMT1-like family K02051 - - 0.00000000000000008274 92.0
HFD3_k127_105175_0 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 434.0
HFD3_k127_105175_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 290.0
HFD3_k127_105175_10 thiamine-containing compound biosynthetic process K02051 - - 0.00000000003888 74.0
HFD3_k127_105175_11 thiamine-containing compound biosynthetic process K02051 - - 0.0000000003906 71.0
HFD3_k127_105175_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000003758 226.0
HFD3_k127_105175_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000001108 216.0
HFD3_k127_105175_4 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000002651 221.0
HFD3_k127_105175_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000001535 183.0
HFD3_k127_105175_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000001121 176.0
HFD3_k127_105175_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000004874 146.0
HFD3_k127_105175_8 ABC transporter substrate binding protein - - - 0.00000000000000000000001723 111.0
HFD3_k127_105175_9 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0000000000009162 79.0
HFD3_k127_1056990_0 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 336.0
HFD3_k127_1056990_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 313.0
HFD3_k127_1056990_2 Psort location CytoplasmicMembrane, score 10.00 - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000007072 219.0
HFD3_k127_1056990_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000009574 202.0
HFD3_k127_1056990_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001178 168.0
HFD3_k127_1056990_5 - - - - 0.00001148 53.0
HFD3_k127_1056990_6 EamA-like transporter family - - - 0.0001669 51.0
HFD3_k127_1066604_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.736e-208 662.0
HFD3_k127_1066604_1 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 458.0
HFD3_k127_1066604_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000001165 191.0
HFD3_k127_1066604_11 Zn-dependent hydrolases of the - - - 0.00000000000000000000000000000000000000000000000421 180.0
HFD3_k127_1066604_12 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000615 178.0
HFD3_k127_1066604_13 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000004078 156.0
HFD3_k127_1066604_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000005419 164.0
HFD3_k127_1066604_15 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000005893 153.0
HFD3_k127_1066604_16 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000002079 137.0
HFD3_k127_1066604_17 Cytidylate kinase-like family - - - 0.0000000000000000000000000000006956 132.0
HFD3_k127_1066604_18 - - - - 0.00000000000000000004804 96.0
HFD3_k127_1066604_19 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000005154 92.0
HFD3_k127_1066604_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
HFD3_k127_1066604_21 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000001138 59.0
HFD3_k127_1066604_22 DnaK suppressor protein - - - 0.00000122 57.0
HFD3_k127_1066604_25 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.00009527 48.0
HFD3_k127_1066604_26 Transcription factor zinc-finger K09981 - - 0.0001969 49.0
HFD3_k127_1066604_27 Copper resistance protein CopC K14166 - - 0.0003634 47.0
HFD3_k127_1066604_3 acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 383.0
HFD3_k127_1066604_4 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 324.0
HFD3_k127_1066604_5 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 312.0
HFD3_k127_1066604_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 301.0
HFD3_k127_1066604_7 Cytochrome oxidase assembly protein K02259,K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003496 284.0
HFD3_k127_1066604_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
HFD3_k127_1066604_9 Domain of unknown function DUF108 - - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
HFD3_k127_1091227_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 385.0
HFD3_k127_1091227_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000001074 186.0
HFD3_k127_1091227_2 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000001547 144.0
HFD3_k127_1091227_4 Tfp pilus assembly protein FimV - - - 0.0000431 55.0
HFD3_k127_1099455_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 571.0
HFD3_k127_1099455_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 368.0
HFD3_k127_1099455_10 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000000000000000000000000009907 120.0
HFD3_k127_1099455_11 - - - - 0.00000000000000000000000004045 108.0
HFD3_k127_1099455_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000084 114.0
HFD3_k127_1099455_13 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000007271 63.0
HFD3_k127_1099455_14 - - - - 0.000000009501 66.0
HFD3_k127_1099455_15 Domain of unknown function (DUF4384) - - - 0.0000005787 63.0
HFD3_k127_1099455_16 ribonuclease activity - - - 0.000002665 55.0
HFD3_k127_1099455_17 - - - - 0.0001541 48.0
HFD3_k127_1099455_18 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.0007204 44.0
HFD3_k127_1099455_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 359.0
HFD3_k127_1099455_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002003 294.0
HFD3_k127_1099455_4 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
HFD3_k127_1099455_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
HFD3_k127_1099455_6 CHAT domain - - - 0.00000000000000000000000000000000000000000001735 183.0
HFD3_k127_1099455_7 PIN domain - - - 0.00000000000000000000000000000000000000001897 156.0
HFD3_k127_1099455_8 Domain of unknown function (DUF4258) - - - 0.000000000000000000000000000000000000003335 148.0
HFD3_k127_1099455_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.0000000000000000000000000000004012 136.0
HFD3_k127_1114436_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 603.0
HFD3_k127_1114436_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 512.0
HFD3_k127_1114436_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000003456 224.0
HFD3_k127_1114436_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000006498 211.0
HFD3_k127_1114436_4 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000002183 204.0
HFD3_k127_1114436_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000001633 196.0
HFD3_k127_1114436_6 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.0000000000000000000000000000003324 132.0
HFD3_k127_1114436_7 Belongs to the peptidase S8 family K12287 - - 0.000000003136 63.0
HFD3_k127_1135309_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 360.0
HFD3_k127_1135309_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
HFD3_k127_1135309_2 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000002871 212.0
HFD3_k127_1135309_3 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000114 145.0
HFD3_k127_1143081_0 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 4.498e-254 790.0
HFD3_k127_1143081_1 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 586.0
HFD3_k127_1143081_2 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 459.0
HFD3_k127_1143081_3 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 392.0
HFD3_k127_1143081_4 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 377.0
HFD3_k127_1143081_5 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 330.0
HFD3_k127_1143081_6 YceI-like domain - - - 0.0000000000000000000000000000000000000309 150.0
HFD3_k127_1143081_7 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000009483 138.0
HFD3_k127_1143081_8 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K07006 - - 0.0000000000003054 78.0
HFD3_k127_1143081_9 Helix-turn-helix domain - - - 0.000000003064 60.0
HFD3_k127_1143859_0 Sigma-54 interaction domain K07714,K07715 - - 2.418e-194 616.0
HFD3_k127_1143859_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 440.0
HFD3_k127_1143859_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.00000000000000000000000000000000000000002618 158.0
HFD3_k127_1143859_11 nuclear chromosome segregation - - - 0.000000000005112 74.0
HFD3_k127_1143859_12 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000003392 66.0
HFD3_k127_1143859_2 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 390.0
HFD3_k127_1143859_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 384.0
HFD3_k127_1143859_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 382.0
HFD3_k127_1143859_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 325.0
HFD3_k127_1143859_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
HFD3_k127_1143859_7 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001428 250.0
HFD3_k127_1143859_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000003347 224.0
HFD3_k127_1143859_9 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000002995 199.0
HFD3_k127_1166341_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 524.0
HFD3_k127_1166341_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 492.0
HFD3_k127_1166341_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000004076 68.0
HFD3_k127_1166341_2 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 443.0
HFD3_k127_1166341_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 368.0
HFD3_k127_1166341_4 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 292.0
HFD3_k127_1166341_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000007814 217.0
HFD3_k127_1166341_6 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000004952 208.0
HFD3_k127_1166341_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000001483 208.0
HFD3_k127_1166341_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000002383 84.0
HFD3_k127_1166341_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000001837 75.0
HFD3_k127_1187048_0 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 549.0
HFD3_k127_1187048_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 349.0
HFD3_k127_1187048_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000001276 214.0
HFD3_k127_1187048_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000001063 213.0
HFD3_k127_1187048_4 Isochorismatase family - - - 0.00000000000002527 78.0
HFD3_k127_119224_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 6.585e-239 747.0
HFD3_k127_119224_1 radical SAM domain protein - - - 1.82e-223 702.0
HFD3_k127_119224_2 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000002597 208.0
HFD3_k127_119224_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000000000135 179.0
HFD3_k127_1212375_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 441.0
HFD3_k127_1212375_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 340.0
HFD3_k127_1212375_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000006559 198.0
HFD3_k127_1212375_3 Pfam:Methyltransf_26 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000001938 167.0
HFD3_k127_1212375_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000001371 121.0
HFD3_k127_1212375_5 Bacterial extracellular solute-binding protein - - - 0.00000000000000009923 90.0
HFD3_k127_1212375_6 PFAM Alcohol dehydrogenase, zinc-binding K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000009817 57.0
HFD3_k127_1212375_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.0001189 54.0
HFD3_k127_1220788_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 559.0
HFD3_k127_1220788_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 499.0
HFD3_k127_1220788_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000002297 203.0
HFD3_k127_1220788_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000894 205.0
HFD3_k127_1220788_12 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000004852 194.0
HFD3_k127_1220788_13 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000002492 137.0
HFD3_k127_1220788_14 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000001015 128.0
HFD3_k127_1220788_15 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000111 118.0
HFD3_k127_1220788_16 Transmembrane secretion effector K08225 - - 0.0000000000000008993 81.0
HFD3_k127_1220788_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 480.0
HFD3_k127_1220788_3 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 437.0
HFD3_k127_1220788_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 401.0
HFD3_k127_1220788_5 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 368.0
HFD3_k127_1220788_6 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 317.0
HFD3_k127_1220788_7 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 303.0
HFD3_k127_1220788_8 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
HFD3_k127_1220788_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001187 230.0
HFD3_k127_1227326_0 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 458.0
HFD3_k127_1227326_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 395.0
HFD3_k127_1227326_2 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000001835 227.0
HFD3_k127_1227326_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000001188 168.0
HFD3_k127_1227326_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000031 74.0
HFD3_k127_1227326_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000001975 69.0
HFD3_k127_123647_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000109 126.0
HFD3_k127_123647_1 NMT1-like family - - - 0.0000000000000000000000000131 120.0
HFD3_k127_123647_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000003198 98.0
HFD3_k127_123647_3 NMT1-like family - - - 0.00000002131 62.0
HFD3_k127_1259651_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 488.0
HFD3_k127_1259651_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 285.0
HFD3_k127_1259651_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
HFD3_k127_1259651_3 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000001633 198.0
HFD3_k127_1259651_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000001213 184.0
HFD3_k127_1259651_5 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000004735 145.0
HFD3_k127_1259651_6 Belongs to the 'phage' integrase family - - - 0.000000000000002707 79.0
HFD3_k127_1259651_7 membrane - - - 0.000000000000004917 88.0
HFD3_k127_1271378_0 Beta-lactamase superfamily domain - - - 1.027e-252 783.0
HFD3_k127_1271378_1 PFAM cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 475.0
HFD3_k127_1271378_2 Belongs to the OprB family K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007128 259.0
HFD3_k127_1271378_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000001325 115.0
HFD3_k127_1271378_4 Phosphopantetheine attachment site - - - 0.00000000000000002059 84.0
HFD3_k127_1291730_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.697e-194 633.0
HFD3_k127_1291730_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000004474 105.0
HFD3_k127_1291730_2 AMP-binding enzyme K04110 - 6.2.1.25 0.0000000000000000001694 90.0
HFD3_k127_1291730_3 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.000000000000000001005 102.0
HFD3_k127_130660_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1162.0
HFD3_k127_130660_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1030.0
HFD3_k127_130660_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000006395 70.0
HFD3_k127_130660_11 HWE histidine kinase - - - 0.00002077 52.0
HFD3_k127_130660_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.852e-241 756.0
HFD3_k127_130660_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 552.0
HFD3_k127_130660_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 413.0
HFD3_k127_130660_5 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000003348 177.0
HFD3_k127_130660_6 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000004858 166.0
HFD3_k127_130660_7 Histidine kinase K02482,K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000005046 128.0
HFD3_k127_130660_8 response to oxidative stress K04063 - - 0.00000000000000000000000000008736 120.0
HFD3_k127_130660_9 CBS domain K04767 - - 0.00000000000000000001995 102.0
HFD3_k127_1328744_0 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 428.0
HFD3_k127_1328744_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 305.0
HFD3_k127_1328744_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003213 277.0
HFD3_k127_1328744_3 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001737 273.0
HFD3_k127_1328744_4 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004815 257.0
HFD3_k127_1328744_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000004634 231.0
HFD3_k127_1328744_6 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000003595 231.0
HFD3_k127_1328744_7 PFAM Thiamine pyrophosphate K00170,K19071 - 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000004048 205.0
HFD3_k127_1328744_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000002801 77.0
HFD3_k127_1328744_9 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00003191 53.0
HFD3_k127_139325_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 342.0
HFD3_k127_139325_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002382 255.0
HFD3_k127_139325_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000001648 204.0
HFD3_k127_139325_3 NMT1-like family - - - 0.00000000001227 70.0
HFD3_k127_139325_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000004619 74.0
HFD3_k127_139325_5 NMT1-like family K02051 - - 0.0000000003163 71.0
HFD3_k127_139325_6 Pfam Amidohydrolase - - - 0.000003815 50.0
HFD3_k127_1395731_0 FAD linked oxidase - - - 3.178e-246 767.0
HFD3_k127_1395731_1 ATPase associated with various cellular activities, AAA_5 K02584 - - 3.8e-219 698.0
HFD3_k127_1395731_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 9.341e-212 671.0
HFD3_k127_1395731_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 295.0
HFD3_k127_1395731_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000002802 183.0
HFD3_k127_1395731_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000002077 175.0
HFD3_k127_1395731_6 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000002599 83.0
HFD3_k127_1395731_7 Ftsk_gamma K03466 - - 0.00000000257 61.0
HFD3_k127_1395731_8 Methyltransferase - - - 0.0003462 48.0
HFD3_k127_141354_0 transport system fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 604.0
HFD3_k127_141354_2 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006143 240.0
HFD3_k127_141354_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000008599 238.0
HFD3_k127_141354_4 TRAP transporter solute receptor TAXI family protein K07080 - - 0.0000000000000000000000000000000000000000000000000001981 200.0
HFD3_k127_141354_5 TRAP transporter solute receptor TAXI family protein K07080 - - 0.00000000000000000000000000000000000000000000002306 184.0
HFD3_k127_141354_6 Metallopeptidase family M24 - - - 0.000000000000000005245 97.0
HFD3_k127_141354_7 Tripartite tricarboxylate transporter family receptor - - - 0.00002496 49.0
HFD3_k127_142961_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 444.0
HFD3_k127_142961_1 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 397.0
HFD3_k127_142961_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000002368 123.0
HFD3_k127_142961_3 Protein of unknown function (DUF3106) - - - 0.00000000000001319 81.0
HFD3_k127_142961_4 Heavy-metal resistance - - - 0.00000000006143 70.0
HFD3_k127_142961_5 Putative zinc-finger - - - 0.0004458 49.0
HFD3_k127_1435780_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 5.035e-259 808.0
HFD3_k127_1435780_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
HFD3_k127_1435780_2 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000005261 213.0
HFD3_k127_1435780_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000003945 154.0
HFD3_k127_1435780_5 BON domain - - - 0.000000001106 61.0
HFD3_k127_1442512_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 594.0
HFD3_k127_1442512_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005776 282.0
HFD3_k127_1442512_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
HFD3_k127_1442512_3 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000004827 196.0
HFD3_k127_1442512_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000004581 186.0
HFD3_k127_1442512_5 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000003858 119.0
HFD3_k127_1442512_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11354 - 2.7.13.3 0.0000000000004698 68.0
HFD3_k127_1442512_7 type IV pilus modification protein PilV K02458,K02671 - - 0.0000001042 59.0
HFD3_k127_1442512_8 Type IV Pilus-assembly protein W K02672 - - 0.00004097 53.0
HFD3_k127_1442512_9 Prokaryotic N-terminal methylation motif K02679 - - 0.0001781 50.0
HFD3_k127_1456658_0 PFAM Glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 339.0
HFD3_k127_1456658_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 316.0
HFD3_k127_1456658_2 glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000001952 223.0
HFD3_k127_1456658_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000002114 147.0
HFD3_k127_1456658_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000005901 133.0
HFD3_k127_1473047_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 511.0
HFD3_k127_1473047_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 473.0
HFD3_k127_1473047_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 415.0
HFD3_k127_1473047_3 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007527 267.0
HFD3_k127_1473047_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
HFD3_k127_1473047_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 258.0
HFD3_k127_1473047_6 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000001473 232.0
HFD3_k127_1473047_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000007081 195.0
HFD3_k127_1473047_8 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000054 108.0
HFD3_k127_1554514_0 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 458.0
HFD3_k127_1554514_1 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 357.0
HFD3_k127_1554514_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 303.0
HFD3_k127_1554514_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
HFD3_k127_1554514_4 NMT1-like family K02051 - - 0.000000000000000001864 96.0
HFD3_k127_1554514_5 Protein of unknown function DUF45 K07043 - - 0.00000002314 57.0
HFD3_k127_1562977_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.19e-290 906.0
HFD3_k127_1562977_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.87e-256 801.0
HFD3_k127_1562977_10 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000009116 143.0
HFD3_k127_1562977_11 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00004244 52.0
HFD3_k127_1562977_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.507e-254 812.0
HFD3_k127_1562977_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 562.0
HFD3_k127_1562977_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
HFD3_k127_1562977_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000346 250.0
HFD3_k127_1562977_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000002611 241.0
HFD3_k127_1562977_7 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000003864 178.0
HFD3_k127_1562977_8 - K09771 - - 0.0000000000000000000000000000000000003211 142.0
HFD3_k127_1562977_9 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000005013 153.0
HFD3_k127_1575652_0 Sulfatase K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
HFD3_k127_1575652_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007842 265.0
HFD3_k127_1575652_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 254.0
HFD3_k127_1575652_3 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004004 254.0
HFD3_k127_1575652_4 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000001239 210.0
HFD3_k127_1575652_5 Membrane protein involved in D-alanine export - - - 0.0000000000000000000000000000000000000000002057 176.0
HFD3_k127_1581394_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
HFD3_k127_1581394_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
HFD3_k127_1581394_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000004223 180.0
HFD3_k127_1581394_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000001501 171.0
HFD3_k127_1581394_4 MFS_1 like family - - - 0.00000000000000000000000000000000000000000001772 177.0
HFD3_k127_1581394_5 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000000001218 158.0
HFD3_k127_1581394_6 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.0000000000000000000000000003161 120.0
HFD3_k127_1581394_7 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000001189 113.0
HFD3_k127_1581394_8 Luciferase-like monooxygenase - - - 0.00000000000000007587 88.0
HFD3_k127_1581394_9 alpha/beta hydrolase fold - - - 0.00000000000000314 86.0
HFD3_k127_1599787_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 595.0
HFD3_k127_1599787_1 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 334.0
HFD3_k127_1599787_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000009991 166.0
HFD3_k127_1599787_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000001214 114.0
HFD3_k127_1599787_4 NUDIX domain - - - 0.0000000000000000000000004819 111.0
HFD3_k127_1599787_5 Putative zinc-finger - - - 0.0000000000009529 80.0
HFD3_k127_1605497_0 - - - - 0.000000000000000000000000000000000000000001877 158.0
HFD3_k127_1605497_1 Major facilitator superfamily - - - 0.00000000000000000000000001273 114.0
HFD3_k127_1605497_2 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000003399 110.0
HFD3_k127_1605497_3 Plasmid stabilization system - - - 0.0000000000000000006938 87.0
HFD3_k127_1605497_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000248 53.0
HFD3_k127_1605497_5 DNA polymerase beta domain protein region - - - 0.00002466 51.0
HFD3_k127_1605497_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000879 45.0
HFD3_k127_1606747_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 309.0
HFD3_k127_1606747_1 quinone binding K12057,K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 256.0
HFD3_k127_1606747_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000003963 175.0
HFD3_k127_1606747_3 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000001519 151.0
HFD3_k127_1606747_4 SCO1/SenC K07152 - - 0.0000000000000000000000000000003024 130.0
HFD3_k127_1606747_5 PFAM von Willebrand factor type A - - - 0.0000000000000000000000001006 121.0
HFD3_k127_1606747_6 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000048 55.0
HFD3_k127_1606747_7 Rhodanese Homology Domain K03972 - - 0.0002768 48.0
HFD3_k127_1630875_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 463.0
HFD3_k127_1630875_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 385.0
HFD3_k127_1630875_2 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002399 267.0
HFD3_k127_1630875_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000007267 203.0
HFD3_k127_1630875_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000008794 165.0
HFD3_k127_1630875_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000003303 163.0
HFD3_k127_1630875_6 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000001782 153.0
HFD3_k127_1630875_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003081 146.0
HFD3_k127_1630875_8 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000001436 128.0
HFD3_k127_1630875_9 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000003745 115.0
HFD3_k127_1637341_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 432.0
HFD3_k127_1637341_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000001044 172.0
HFD3_k127_1648114_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.55e-243 766.0
HFD3_k127_1648114_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 554.0
HFD3_k127_1648114_2 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 467.0
HFD3_k127_1648114_3 methylamine metabolic process K15977 - - 0.0000000000099 72.0
HFD3_k127_1648114_4 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000003152 63.0
HFD3_k127_1659369_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 351.0
HFD3_k127_1659369_1 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 329.0
HFD3_k127_1659369_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 294.0
HFD3_k127_1659369_3 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000003291 208.0
HFD3_k127_1659369_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000136 186.0
HFD3_k127_1659369_5 NMT1-like family K02051 - - 0.00000000000000000000000004725 120.0
HFD3_k127_1659369_6 - - - - 0.0000000000003409 76.0
HFD3_k127_1659369_7 Transposase IS200 like K07491 - - 0.0000006713 56.0
HFD3_k127_1659401_0 KR domain K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 259.0
HFD3_k127_1659401_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
HFD3_k127_1659401_2 PAS fold - - - 0.00000000000000000000000000000000000000000000005348 177.0
HFD3_k127_1659401_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000001449 151.0
HFD3_k127_1659401_4 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000007736 98.0
HFD3_k127_1659401_5 Belongs to the ompA family - - - 0.000000000000006501 84.0
HFD3_k127_1659401_6 Transmembrane secretion effector - - - 0.0000000000607 66.0
HFD3_k127_1659401_7 thiamine-containing compound biosynthetic process K02051 - - 0.0000001734 63.0
HFD3_k127_1669312_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 363.0
HFD3_k127_1669312_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000001834 140.0
HFD3_k127_1669312_2 TonB C terminal - - - 0.0001232 53.0
HFD3_k127_1674331_0 Fe-S oxidoreductase - - - 1.384e-255 797.0
HFD3_k127_1674331_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 514.0
HFD3_k127_1674331_2 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 310.0
HFD3_k127_1674331_3 regulatory protein IclR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007436 281.0
HFD3_k127_1674331_4 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
HFD3_k127_1674331_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily K18926 - - 0.00000000000000000000000000000000000000000000000001232 198.0
HFD3_k127_1674331_6 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.0000000000000000000002882 101.0
HFD3_k127_1674331_7 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000000207 91.0
HFD3_k127_1674331_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000001456 57.0
HFD3_k127_1679539_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 537.0
HFD3_k127_1679539_1 Zn-dependent alcohol dehydrogenases K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 286.0
HFD3_k127_1679539_2 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003477 269.0
HFD3_k127_1679539_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000002281 174.0
HFD3_k127_1679539_4 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.0000000000000000000000000000000000003256 147.0
HFD3_k127_1679539_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000001134 143.0
HFD3_k127_1679539_6 photosynthesis K02656 - - 0.000000000000284 78.0
HFD3_k127_1679539_7 deoxyhypusine monooxygenase activity - - - 0.0003393 50.0
HFD3_k127_1680632_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 580.0
HFD3_k127_1680632_1 Glycosyl transferases group 1 K16697 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 358.0
HFD3_k127_1680632_10 Pectate lyase superfamily protein - - - 0.000000004686 68.0
HFD3_k127_1680632_11 Glycosyl transferases group 1 - - - 0.00000003551 65.0
HFD3_k127_1680632_12 - - - - 0.00002538 57.0
HFD3_k127_1680632_2 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 340.0
HFD3_k127_1680632_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000003937 202.0
HFD3_k127_1680632_4 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000008288 166.0
HFD3_k127_1680632_5 TIGRFAM methyltransferase FkbM family - - - 0.00000000000000000000000000007566 126.0
HFD3_k127_1680632_6 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000003485 116.0
HFD3_k127_1680632_7 Type II secretory pathway component ExeA K02450 - - 0.0000000000000000000002091 112.0
HFD3_k127_1680632_8 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000007213 78.0
HFD3_k127_1680632_9 SPTR Glycosyl transferase group 1 - - - 0.00000000008274 74.0
HFD3_k127_1684715_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
HFD3_k127_1684715_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004898 270.0
HFD3_k127_1684715_2 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
HFD3_k127_1711568_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1058.0
HFD3_k127_1711568_1 DNA topoisomerase II activity K03167 - 5.99.1.3 1.269e-302 940.0
HFD3_k127_1711568_10 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 307.0
HFD3_k127_1711568_11 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
HFD3_k127_1711568_12 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000002211 217.0
HFD3_k127_1711568_13 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000002349 192.0
HFD3_k127_1711568_14 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000003583 173.0
HFD3_k127_1711568_15 R3H domain protein K06346 - - 0.000000000000000000000000000000000000004384 157.0
HFD3_k127_1711568_16 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000001659 136.0
HFD3_k127_1711568_17 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002101 93.0
HFD3_k127_1711568_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000007224 93.0
HFD3_k127_1711568_19 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000262 78.0
HFD3_k127_1711568_2 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 1e-231 730.0
HFD3_k127_1711568_20 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005225 76.0
HFD3_k127_1711568_21 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000041 66.0
HFD3_k127_1711568_3 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.588e-202 634.0
HFD3_k127_1711568_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 536.0
HFD3_k127_1711568_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 429.0
HFD3_k127_1711568_6 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 339.0
HFD3_k127_1711568_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 346.0
HFD3_k127_1711568_8 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 329.0
HFD3_k127_1711568_9 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 313.0
HFD3_k127_1714098_0 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000000967 119.0
HFD3_k127_1714098_3 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00006179 51.0
HFD3_k127_1723545_0 proline dipeptidase activity - - - 8.522e-241 749.0
HFD3_k127_1723545_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 531.0
HFD3_k127_1723545_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 302.0
HFD3_k127_1723545_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 284.0
HFD3_k127_1723545_4 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
HFD3_k127_1723545_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HFD3_k127_1723545_6 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000005723 215.0
HFD3_k127_1723545_7 Smr domain K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.000000000000000000000000001316 116.0
HFD3_k127_1727816_0 Amino acid permease - - - 1.012e-208 669.0
HFD3_k127_1727816_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 525.0
HFD3_k127_1727816_10 Transposase domain (DUF772) - - - 0.000000004753 60.0
HFD3_k127_1727816_11 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.0009014 46.0
HFD3_k127_1727816_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 364.0
HFD3_k127_1727816_3 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003536 261.0
HFD3_k127_1727816_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007879 261.0
HFD3_k127_1727816_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000002881 177.0
HFD3_k127_1727816_6 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000004621 156.0
HFD3_k127_1727816_7 PIN domain K07063 - - 0.0000000000000000000000000000000000001256 146.0
HFD3_k127_1727816_8 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000000006057 105.0
HFD3_k127_1727816_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000002642 81.0
HFD3_k127_1742478_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.618e-283 890.0
HFD3_k127_1742478_1 cellulose binding - - - 1.761e-224 698.0
HFD3_k127_1742478_10 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000001919 58.0
HFD3_k127_1742478_2 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 336.0
HFD3_k127_1742478_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
HFD3_k127_1742478_4 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000001588 169.0
HFD3_k127_1742478_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000000000738 160.0
HFD3_k127_1742478_6 Chromate transporter K07240 - - 0.00000000000000000000000000000000000007199 157.0
HFD3_k127_1742478_7 YCII-related domain - - - 0.0000000000000000000000000000000000001475 142.0
HFD3_k127_1742478_8 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000005541 156.0
HFD3_k127_1742773_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.315e-212 671.0
HFD3_k127_1742773_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 565.0
HFD3_k127_1742773_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 503.0
HFD3_k127_1742773_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 427.0
HFD3_k127_1742773_4 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 410.0
HFD3_k127_1742773_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002905 280.0
HFD3_k127_1742773_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000009137 268.0
HFD3_k127_1742773_7 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000002538 132.0
HFD3_k127_1743436_0 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 1.359e-204 657.0
HFD3_k127_1743436_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 292.0
HFD3_k127_1743436_2 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.00000000000000005028 90.0
HFD3_k127_1752196_0 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 297.0
HFD3_k127_1752196_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000001483 121.0
HFD3_k127_1752196_2 - - - - 0.00001506 49.0
HFD3_k127_1762349_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 460.0
HFD3_k127_1762349_1 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 435.0
HFD3_k127_1762349_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 299.0
HFD3_k127_1762349_3 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 297.0
HFD3_k127_1762349_4 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000001365 103.0
HFD3_k127_1762349_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.000000000000000002261 89.0
HFD3_k127_1762349_6 CoA-transferase family III - - - 0.000000000001358 70.0
HFD3_k127_1766979_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 2.555e-220 692.0
HFD3_k127_1766979_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.155e-209 662.0
HFD3_k127_1766979_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 381.0
HFD3_k127_1766979_3 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 375.0
HFD3_k127_1766979_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004536 271.0
HFD3_k127_1766979_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006876 278.0
HFD3_k127_1766979_6 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
HFD3_k127_1766979_7 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000001951 210.0
HFD3_k127_1766979_8 thiamine-containing compound biosynthetic process K02051 - - 0.00000000002223 75.0
HFD3_k127_1766979_9 Regulatory protein, FmdB - - - 0.0000639 48.0
HFD3_k127_1771815_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 429.0
HFD3_k127_1771815_1 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000008437 250.0
HFD3_k127_1771815_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000006656 105.0
HFD3_k127_1771815_3 Substrate binding domain of ABC-type glycine betaine transport system K02051 - - 0.00000000000001385 85.0
HFD3_k127_1771815_4 NMT1-like family K02051 - - 0.0000000000001628 81.0
HFD3_k127_1771815_5 Cupin domain K00450 - 1.13.11.4 0.0000441 51.0
HFD3_k127_1782472_0 Translation-initiation factor 2 K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 453.0
HFD3_k127_1782472_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000003642 224.0
HFD3_k127_1782472_2 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000007077 203.0
HFD3_k127_1782472_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000001226 183.0
HFD3_k127_1782472_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000005564 116.0
HFD3_k127_1782472_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000003964 93.0
HFD3_k127_1782472_6 PFAM IstB domain protein ATP-binding protein - - - 0.00009212 50.0
HFD3_k127_1786391_0 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000001453 184.0
HFD3_k127_1786391_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000022 157.0
HFD3_k127_1786391_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000004234 82.0
HFD3_k127_1800594_0 Flavin containing amine oxidoreductase - - - 1.012e-254 794.0
HFD3_k127_1800594_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 451.0
HFD3_k127_1800594_10 Family of unknown function (DUF5329) - - - 0.00000000000000001046 89.0
HFD3_k127_1800594_11 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000002313 58.0
HFD3_k127_1800594_12 DUF167 K09131 - - 0.0000004761 55.0
HFD3_k127_1800594_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 404.0
HFD3_k127_1800594_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 370.0
HFD3_k127_1800594_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 325.0
HFD3_k127_1800594_5 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007581 282.0
HFD3_k127_1800594_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000242 212.0
HFD3_k127_1800594_7 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000006706 191.0
HFD3_k127_1800594_8 nitrite transmembrane transporter activity K02575,K08223 - - 0.0000000000000000000000000000000001096 148.0
HFD3_k127_1800594_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000007728 124.0
HFD3_k127_1818088_0 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 360.0
HFD3_k127_1818088_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HFD3_k127_1818088_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001858 273.0
HFD3_k127_1818088_3 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001008 253.0
HFD3_k127_1818088_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002631 246.0
HFD3_k127_1818088_5 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000006295 180.0
HFD3_k127_1827113_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 8.09e-289 911.0
HFD3_k127_1827113_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 522.0
HFD3_k127_1827113_2 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 429.0
HFD3_k127_1827113_3 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 304.0
HFD3_k127_1827113_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000001616 180.0
HFD3_k127_1827113_5 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000001205 151.0
HFD3_k127_1827113_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000693 132.0
HFD3_k127_1827113_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000007084 107.0
HFD3_k127_1827113_8 RecX family K03565 - - 0.0000000000000002084 85.0
HFD3_k127_1828726_0 CoA-transferase family III K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 470.0
HFD3_k127_1828726_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 396.0
HFD3_k127_1828726_11 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000008396 147.0
HFD3_k127_1828726_12 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000007877 149.0
HFD3_k127_1828726_13 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000004921 136.0
HFD3_k127_1828726_14 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000009793 134.0
HFD3_k127_1828726_15 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000004318 130.0
HFD3_k127_1828726_16 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000004803 91.0
HFD3_k127_1828726_17 Protein of unknown function (DUF3108) - - - 0.00000000000002389 84.0
HFD3_k127_1828726_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000005604 58.0
HFD3_k127_1828726_19 NMT1-like family K02051 - - 0.000001579 59.0
HFD3_k127_1828726_2 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 317.0
HFD3_k127_1828726_20 NMT1-like family K02051 - - 0.0004721 51.0
HFD3_k127_1828726_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002 292.0
HFD3_k127_1828726_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000002079 230.0
HFD3_k127_1828726_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000005301 211.0
HFD3_k127_1828726_6 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000006733 208.0
HFD3_k127_1828726_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000001608 188.0
HFD3_k127_1828726_8 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000002065 181.0
HFD3_k127_1828726_9 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000344 171.0
HFD3_k127_1848993_0 Aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 8.312e-226 710.0
HFD3_k127_1848993_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.792e-208 676.0
HFD3_k127_1848993_10 photosynthesis - - - 0.00000000000000000000000000000000000000000000001013 175.0
HFD3_k127_1848993_11 Response regulator receiver - - - 0.00000000000000000000001233 107.0
HFD3_k127_1848993_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 511.0
HFD3_k127_1848993_3 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 491.0
HFD3_k127_1848993_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 464.0
HFD3_k127_1848993_5 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 430.0
HFD3_k127_1848993_6 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 379.0
HFD3_k127_1848993_7 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 325.0
HFD3_k127_1848993_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000002616 200.0
HFD3_k127_1848993_9 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.000000000000000000000000000000000000000000000000004271 186.0
HFD3_k127_1853099_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.247e-232 736.0
HFD3_k127_1853099_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 5.214e-207 653.0
HFD3_k127_1853099_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000305 98.0
HFD3_k127_1853099_11 Transposase IS200 like K07491 - - 0.000000000008635 67.0
HFD3_k127_1853099_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
HFD3_k127_1853099_3 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 437.0
HFD3_k127_1853099_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 401.0
HFD3_k127_1853099_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000261 197.0
HFD3_k127_1853099_6 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000001938 139.0
HFD3_k127_1853099_7 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000009932 126.0
HFD3_k127_1853099_8 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000006089 129.0
HFD3_k127_1853099_9 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000001808 98.0
HFD3_k127_1858142_0 Sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 504.0
HFD3_k127_1858142_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 491.0
HFD3_k127_1858142_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
HFD3_k127_1858142_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 252.0
HFD3_k127_1858142_12 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006212 247.0
HFD3_k127_1858142_13 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000514 146.0
HFD3_k127_1858142_14 amine dehydrogenase activity - - - 0.00000000000000000000000001296 113.0
HFD3_k127_1858142_15 Flavodoxin-like fold - - - 0.000000000000000000003061 106.0
HFD3_k127_1858142_16 ABC transporter substrate binding protein K01989 - - 0.0000000000000002073 80.0
HFD3_k127_1858142_17 RDD family - - - 0.00000000000008643 79.0
HFD3_k127_1858142_18 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.000000006891 64.0
HFD3_k127_1858142_19 - - - - 0.0000001051 57.0
HFD3_k127_1858142_2 Oxidoreductase NAD-binding domain K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 484.0
HFD3_k127_1858142_20 - - - - 0.000001204 51.0
HFD3_k127_1858142_21 Putative peptidoglycan binding domain - - - 0.0001752 49.0
HFD3_k127_1858142_3 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 348.0
HFD3_k127_1858142_4 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 323.0
HFD3_k127_1858142_5 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 314.0
HFD3_k127_1858142_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 297.0
HFD3_k127_1858142_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 296.0
HFD3_k127_1858142_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005204 275.0
HFD3_k127_1858142_9 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004961 290.0
HFD3_k127_1927891_0 Belongs to the ClpA ClpB family K03694 - - 4.014e-307 957.0
HFD3_k127_1927891_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 406.0
HFD3_k127_1927891_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 348.0
HFD3_k127_1927891_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 307.0
HFD3_k127_1927891_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003697 261.0
HFD3_k127_1927891_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000002347 184.0
HFD3_k127_1927891_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000001459 131.0
HFD3_k127_1927891_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000004039 65.0
HFD3_k127_1938086_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 391.0
HFD3_k127_1938086_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 390.0
HFD3_k127_1938086_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000009858 228.0
HFD3_k127_1938086_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000001737 220.0
HFD3_k127_1938086_4 - - - - 0.00000000000172 68.0
HFD3_k127_1939229_0 lipopolysaccharide transport K22110 - - 0.0 1157.0
HFD3_k127_1939229_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 528.0
HFD3_k127_1939229_2 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 483.0
HFD3_k127_1939229_3 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
HFD3_k127_1939229_4 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000001066 239.0
HFD3_k127_1939229_5 Ion transport 2 domain protein - - - 0.00000000000000000000000000000187 130.0
HFD3_k127_1939229_6 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000008272 57.0
HFD3_k127_1946194_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.279e-222 714.0
HFD3_k127_1946194_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 514.0
HFD3_k127_1946194_2 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 372.0
HFD3_k127_1946194_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 294.0
HFD3_k127_1946194_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 285.0
HFD3_k127_1946194_5 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000002327 170.0
HFD3_k127_1946194_6 - - - - 0.00000000000000000000000004186 117.0
HFD3_k127_1946194_7 YCII-related domain - - - 0.00000000000000000000000006148 114.0
HFD3_k127_1946194_8 - - - - 0.00000000000004438 81.0
HFD3_k127_1946194_9 EamA-like transporter family K03298 - - 0.0000000001363 72.0
HFD3_k127_195690_0 E1-E2 ATPase K01535 - 3.6.3.6 2.988e-292 919.0
HFD3_k127_195690_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 530.0
HFD3_k127_195690_10 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000003536 90.0
HFD3_k127_195690_11 DNA ligase K01971 - 6.5.1.1 0.00000000000001724 74.0
HFD3_k127_195690_12 Sulphur transport K07112 - - 0.000000001415 61.0
HFD3_k127_195690_13 Transcription factor K21563 - - 0.0000003422 58.0
HFD3_k127_195690_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.000007434 53.0
HFD3_k127_195690_16 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.0001614 44.0
HFD3_k127_195690_2 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003128 281.0
HFD3_k127_195690_3 - - - - 0.0000000000000000000000000000000000000000000000000000000005392 205.0
HFD3_k127_195690_4 Universal stress protein family - - - 0.000000000000000000000000000000000000001067 153.0
HFD3_k127_195690_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000549 138.0
HFD3_k127_195690_6 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000001948 118.0
HFD3_k127_195690_7 oxidase subunit K08738 - - 0.00000000000000000001398 104.0
HFD3_k127_195690_8 Sulphur transport - - - 0.00000000000000000002389 92.0
HFD3_k127_195690_9 PFAM ABC transporter K02003 - - 0.0000000000000000004286 93.0
HFD3_k127_1996736_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.026e-194 620.0
HFD3_k127_1996736_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 563.0
HFD3_k127_1996736_10 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000105 181.0
HFD3_k127_1996736_11 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000004892 169.0
HFD3_k127_1996736_12 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000362 160.0
HFD3_k127_1996736_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000007271 150.0
HFD3_k127_1996736_14 Transcriptional - - - 0.00000000000000000000000000000005789 127.0
HFD3_k127_1996736_15 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 0.0000000000000000000000000000005432 127.0
HFD3_k127_1996736_17 - - - - 0.00000000000000000000001147 102.0
HFD3_k127_1996736_18 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000002831 101.0
HFD3_k127_1996736_19 Domain of unknown function DUF123 - - - 0.000000000000000000002602 102.0
HFD3_k127_1996736_2 homocysteine K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 488.0
HFD3_k127_1996736_20 Thioesterase - - - 0.0000000000000000006697 91.0
HFD3_k127_1996736_21 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000002351 94.0
HFD3_k127_1996736_22 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000003421 87.0
HFD3_k127_1996736_24 NMT1-like family K02051 - - 0.000000000000002306 88.0
HFD3_k127_1996736_26 NMT1-like family K02051 - - 0.000000000414 71.0
HFD3_k127_1996736_27 Transcriptional regulator - - - 0.000000209 61.0
HFD3_k127_1996736_28 Subtilase family - - - 0.0006958 50.0
HFD3_k127_1996736_3 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 391.0
HFD3_k127_1996736_4 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 376.0
HFD3_k127_1996736_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 368.0
HFD3_k127_1996736_6 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 291.0
HFD3_k127_1996736_7 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000007187 218.0
HFD3_k127_1996736_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000007374 207.0
HFD3_k127_1996736_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000121 199.0
HFD3_k127_200328_0 Peroxisomal (S)-2-hydroxy-acid oxidase. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 315.0
HFD3_k127_200328_1 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000005008 198.0
HFD3_k127_200328_2 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000001614 127.0
HFD3_k127_200328_3 NMT1-like family K02051 - - 0.000000000000002128 89.0
HFD3_k127_200328_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000009691 72.0
HFD3_k127_200328_5 Luciferase-like monooxygenase - - - 0.0000000002572 68.0
HFD3_k127_200328_6 Lysin motif - - - 0.0000000205 66.0
HFD3_k127_200328_7 Methionine biosynthesis protein MetW - - - 0.00001661 47.0
HFD3_k127_2013588_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1282.0
HFD3_k127_2013588_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 557.0
HFD3_k127_2013588_10 - - - - 0.00000000000000000000000001296 113.0
HFD3_k127_2013588_11 Transcriptional regulator - - - 0.0000000000000000000005522 101.0
HFD3_k127_2013588_12 Polymer-forming cytoskeletal - - - 0.00000000000000002206 90.0
HFD3_k127_2013588_13 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 0.000000000001713 70.0
HFD3_k127_2013588_15 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.000000618 51.0
HFD3_k127_2013588_16 TPR repeat - - - 0.0001812 47.0
HFD3_k127_2013588_2 4Fe-4S binding domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 406.0
HFD3_k127_2013588_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 299.0
HFD3_k127_2013588_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
HFD3_k127_2013588_5 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001093 254.0
HFD3_k127_2013588_6 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000001243 235.0
HFD3_k127_2013588_7 Cytochrome c K17230 - - 0.00000000000000000000000000000000000000000000000000000002154 207.0
HFD3_k127_2013588_8 PFAM peptidase - - - 0.000000000000000000000000000000000001045 149.0
HFD3_k127_2013588_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000002383 136.0
HFD3_k127_2016106_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 584.0
HFD3_k127_2016106_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006002 277.0
HFD3_k127_2016106_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K20448 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
HFD3_k127_2016106_3 hydroperoxide reductase activity K07486 - - 0.0000000008919 62.0
HFD3_k127_2016106_4 Carboxymuconolactone decarboxylase family - - - 0.000025 48.0
HFD3_k127_2017693_0 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 573.0
HFD3_k127_2017693_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 377.0
HFD3_k127_2017693_2 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 359.0
HFD3_k127_2017693_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 293.0
HFD3_k127_2017693_4 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007279 265.0
HFD3_k127_2017693_5 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000001176 114.0
HFD3_k127_2017693_6 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000962 109.0
HFD3_k127_2017693_7 Transcriptional regulator - - - 0.000000000000000000005728 97.0
HFD3_k127_2017693_8 Alpha beta hydrolase - - - 0.000000000000001017 88.0
HFD3_k127_2028549_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 344.0
HFD3_k127_2028549_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 307.0
HFD3_k127_2028549_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000002051 116.0
HFD3_k127_2028549_11 NMT1-like family K02051 - - 0.000000000000000004642 96.0
HFD3_k127_2028549_12 ligase activity K10701,K10856 - 6.4.1.6,6.4.1.8 0.000000000076 69.0
HFD3_k127_2028549_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007999 258.0
HFD3_k127_2028549_3 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
HFD3_k127_2028549_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000001045 157.0
HFD3_k127_2028549_5 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000003892 150.0
HFD3_k127_2028549_6 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000004231 149.0
HFD3_k127_2028549_7 Bacterial PH domain - - - 0.00000000000000000000000000000000001996 141.0
HFD3_k127_2028549_8 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000002427 139.0
HFD3_k127_2028549_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000006271 117.0
HFD3_k127_2030769_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 608.0
HFD3_k127_2030769_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 460.0
HFD3_k127_2030769_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 240.0
HFD3_k127_2030769_3 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000417 235.0
HFD3_k127_2030769_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000002678 218.0
HFD3_k127_2030769_5 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000006345 193.0
HFD3_k127_2030769_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000003981 150.0
HFD3_k127_2030769_7 thiamine-containing compound biosynthetic process K02051 - - 0.00000000006702 68.0
HFD3_k127_2030769_8 DMSO reductase anchor subunit (DmsC) - - - 0.0000000000741 73.0
HFD3_k127_20393_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 612.0
HFD3_k127_20393_1 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 519.0
HFD3_k127_20393_2 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 293.0
HFD3_k127_20393_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000002055 217.0
HFD3_k127_20393_4 Protein involved in outer membrane biogenesis K07289 - - 0.000000001233 72.0
HFD3_k127_2051405_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 313.0
HFD3_k127_2051405_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000002449 245.0
HFD3_k127_2051405_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000001973 211.0
HFD3_k127_2051405_3 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000002374 180.0
HFD3_k127_2051405_4 PFAM Tetratricopeptide repeat - - - 0.000000001992 60.0
HFD3_k127_2056554_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 393.0
HFD3_k127_2056554_1 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
HFD3_k127_2056554_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000001642 204.0
HFD3_k127_2056554_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000001615 135.0
HFD3_k127_2056554_4 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000001198 129.0
HFD3_k127_2068911_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 616.0
HFD3_k127_2068911_1 Molydopterin dinucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 440.0
HFD3_k127_2068911_2 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
HFD3_k127_2068911_3 PFAM 2Fe-2S -binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000005244 216.0
HFD3_k127_2068911_4 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000003144 175.0
HFD3_k127_2068911_5 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000001358 83.0
HFD3_k127_2072662_0 N-acetyl-gamma-glutamyl-phosphate reductase activity K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 518.0
HFD3_k127_2072662_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 513.0
HFD3_k127_2072662_10 peroxiredoxin activity K03564 - 1.11.1.15 0.0000001422 54.0
HFD3_k127_2072662_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.000006607 51.0
HFD3_k127_2072662_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844,K14940,K18310 - 6.3.1.17,6.3.2.32,6.3.2.41,6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 449.0
HFD3_k127_2072662_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K01438,K05828,K05831 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8,3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 348.0
HFD3_k127_2072662_4 cellular modified histidine biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005129 266.0
HFD3_k127_2072662_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007175 255.0
HFD3_k127_2072662_6 NUDIX hydrolase - - - 0.00000000000000000000000000000000000004754 154.0
HFD3_k127_2072662_7 Redoxin - - - 0.0000000000000000000007086 98.0
HFD3_k127_2072662_8 lysine biosynthesis protein LysW K05826 - - 0.000000000000007081 75.0
HFD3_k127_2072662_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000009124 75.0
HFD3_k127_2104889_0 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 366.0
HFD3_k127_2104889_1 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 321.0
HFD3_k127_2104889_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000002889 259.0
HFD3_k127_2104889_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000009679 57.0
HFD3_k127_2104889_4 SPTR Membrane or secreted protein - - - 0.000004306 55.0
HFD3_k127_213110_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000005167 237.0
HFD3_k127_213110_1 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000003065 142.0
HFD3_k127_213110_2 NMT1-like family - - - 0.0000000005577 70.0
HFD3_k127_2182467_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 317.0
HFD3_k127_2182467_1 PFAM 4Fe-4S binding domain K00184 - - 0.00000000000000000000000000000000000000000000000000002005 194.0
HFD3_k127_2182467_2 NMT1-like family - - - 0.000000000000000000000000000000000001438 151.0
HFD3_k127_2182467_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000001098 136.0
HFD3_k127_2182467_4 Isochorismatase family - - - 0.0000000000000000000003834 103.0
HFD3_k127_2182467_5 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000004422 88.0
HFD3_k127_2182467_6 Alkylmercury lyase - - - 0.000000000000001105 79.0
HFD3_k127_2182467_7 Alkylmercury lyase - - - 0.0000000000005062 70.0
HFD3_k127_2182467_8 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000001028 62.0
HFD3_k127_2191531_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
HFD3_k127_2191531_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 490.0
HFD3_k127_2191531_10 - - - - 0.0000003626 54.0
HFD3_k127_2191531_11 - - - - 0.000004038 52.0
HFD3_k127_2191531_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
HFD3_k127_2191531_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 364.0
HFD3_k127_2191531_4 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 341.0
HFD3_k127_2191531_5 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009726 271.0
HFD3_k127_2191531_6 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000001504 216.0
HFD3_k127_2191531_7 YacP-like NYN domain K06962 - - 0.000000000000000000000001781 109.0
HFD3_k127_2191531_8 - - - - 0.00000000001049 68.0
HFD3_k127_2191531_9 NMT1-like family K02051 - - 0.0000000003052 68.0
HFD3_k127_220637_0 choline dehydrogenase activity - - - 2.305e-212 666.0
HFD3_k127_220637_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 475.0
HFD3_k127_2219057_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 305.0
HFD3_k127_2219057_1 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000001869 139.0
HFD3_k127_2219057_2 nuclease (RecB family) - - - 0.0000000000000000000000000001008 127.0
HFD3_k127_2219057_3 NMT1-like family K02051 - - 0.0000000000000002687 91.0
HFD3_k127_2226672_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 314.0
HFD3_k127_2226672_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 308.0
HFD3_k127_2226672_3 O-methyltransferase - - - 0.00000000000000000000000000000000000008814 149.0
HFD3_k127_2226672_4 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000002137 144.0
HFD3_k127_2226672_5 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000001951 107.0
HFD3_k127_2280677_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1790.0
HFD3_k127_2280677_1 Protein of unknown function (DUF983) - - - 0.000000000000000000007376 98.0
HFD3_k127_2280677_2 - - - - 0.000000000001126 72.0
HFD3_k127_2333021_0 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 403.0
HFD3_k127_2333021_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009008 289.0
HFD3_k127_2333021_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001075 257.0
HFD3_k127_2333021_3 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000001444 204.0
HFD3_k127_2333021_4 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000284 149.0
HFD3_k127_2333021_5 - - - - 0.0000000000000000000000002459 112.0
HFD3_k127_2333021_6 ParB domain protein nuclease K03497 - - 0.00000004357 63.0
HFD3_k127_2333021_7 TonB C terminal K03646 - - 0.00001435 50.0
HFD3_k127_2333021_8 DNA integration - - - 0.00003999 49.0
HFD3_k127_2348946_0 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000000000007433 199.0
HFD3_k127_2348946_1 Belongs to the ompA family K03640 - - 0.000000000000000000003885 104.0
HFD3_k127_2348946_2 Dodecin K09165 - - 0.00000000000000007926 82.0
HFD3_k127_2351725_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 472.0
HFD3_k127_2351725_1 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 350.0
HFD3_k127_2351725_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 291.0
HFD3_k127_2351725_3 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000001033 188.0
HFD3_k127_2351725_4 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000005692 171.0
HFD3_k127_2351725_5 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000001323 172.0
HFD3_k127_236509_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 488.0
HFD3_k127_236509_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000004933 222.0
HFD3_k127_236509_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000002356 212.0
HFD3_k127_236509_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000003456 176.0
HFD3_k127_236509_4 Flavin reductase like domain K09024 - - 0.0000000000000000000000000000000000000003387 156.0
HFD3_k127_236509_5 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000001175 153.0
HFD3_k127_236509_6 Short-chain dehydrogenase reductase Sdr - - - 0.00000000000000003356 92.0
HFD3_k127_236509_7 Protein of unknown function (DUF5131) - - - 0.0000000002753 61.0
HFD3_k127_2365106_0 2-methylcitrate dehydratase K01720 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 2.789e-224 703.0
HFD3_k127_2365106_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 2.045e-212 695.0
HFD3_k127_2365106_10 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000008928 203.0
HFD3_k127_2365106_11 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000001614 155.0
HFD3_k127_2365106_12 NMT1-like family K02051 - - 0.00000000000000008775 92.0
HFD3_k127_2365106_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0002392 48.0
HFD3_k127_2365106_2 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 508.0
HFD3_k127_2365106_3 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 492.0
HFD3_k127_2365106_4 FAD binding domain K05898,K13796 - 1.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 457.0
HFD3_k127_2365106_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 402.0
HFD3_k127_2365106_6 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 377.0
HFD3_k127_2365106_7 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 317.0
HFD3_k127_2365106_8 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 294.0
HFD3_k127_2365106_9 Mmge prpd family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001046 274.0
HFD3_k127_2371303_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.831e-223 701.0
HFD3_k127_2371303_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000003833 185.0
HFD3_k127_2371303_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000003933 164.0
HFD3_k127_2383212_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 552.0
HFD3_k127_2383212_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 424.0
HFD3_k127_2383212_10 PFAM TM2 domain containing protein - - - 0.000001669 53.0
HFD3_k127_2383212_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 316.0
HFD3_k127_2383212_3 Putative cyclase K14250 - - 0.0000000000000000000000000000000000000000000000000000009644 211.0
HFD3_k127_2383212_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000001884 184.0
HFD3_k127_2383212_5 Putative cyclase - - - 0.00000000000000000000000000000000000000000000001668 189.0
HFD3_k127_2383212_7 Major Facilitator Superfamily - - - 0.000000000000000000000006005 115.0
HFD3_k127_2383212_8 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000000000005748 80.0
HFD3_k127_2383212_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000123 66.0
HFD3_k127_2387618_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 455.0
HFD3_k127_2387618_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 396.0
HFD3_k127_2387618_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
HFD3_k127_2387618_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000007007 160.0
HFD3_k127_2387618_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000001177 140.0
HFD3_k127_2387618_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000001566 122.0
HFD3_k127_2387618_6 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000008479 89.0
HFD3_k127_2387618_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000002305 91.0
HFD3_k127_2387618_8 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000001616 86.0
HFD3_k127_2390260_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 428.0
HFD3_k127_2390260_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000001459 240.0
HFD3_k127_2390260_2 Mechanosensitive ion channel - - - 0.000003205 51.0
HFD3_k127_2390355_0 Sulfatase K01130 - 3.1.6.1 0.0 1211.0
HFD3_k127_2390355_1 Sulfatase K01130 - 3.1.6.1 0.0 1202.0
HFD3_k127_2390355_10 Belongs to the ompA family K03286 - - 0.00000000000000000000000001335 116.0
HFD3_k127_2390355_11 Domain of unknown function (DUF4410) - - - 0.0000000000000000009006 88.0
HFD3_k127_2390355_12 Belongs to the ompA family K03286 - - 0.00000000000000008248 94.0
HFD3_k127_2390355_13 Protein of unknown function (DUF1622) - - - 0.0002075 48.0
HFD3_k127_2390355_2 Sulfatase - - - 1.39e-292 902.0
HFD3_k127_2390355_3 PFAM Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 607.0
HFD3_k127_2390355_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 278.0
HFD3_k127_2390355_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001248 294.0
HFD3_k127_2390355_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007315 283.0
HFD3_k127_2390355_7 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008368 244.0
HFD3_k127_2390355_8 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000000000000000000001646 195.0
HFD3_k127_2390355_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000003135 148.0
HFD3_k127_2401382_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.017e-247 783.0
HFD3_k127_2401382_1 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 549.0
HFD3_k127_2401382_11 AI-2E family transporter - - - 0.00000000000005601 79.0
HFD3_k127_2401382_12 - - - - 0.00000000172 60.0
HFD3_k127_2401382_13 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000005049 61.0
HFD3_k127_2401382_14 Transcription factor zinc-finger K09981 - - 0.00000007769 58.0
HFD3_k127_2401382_15 - - - - 0.0004438 47.0
HFD3_k127_2401382_2 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 463.0
HFD3_k127_2401382_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 336.0
HFD3_k127_2401382_4 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003512 287.0
HFD3_k127_2401382_5 COG0589 Universal stress protein UspA and related K14055 - - 0.0000000000000000000000000000000000005772 151.0
HFD3_k127_2401382_6 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000001448 111.0
HFD3_k127_2401382_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000002415 96.0
HFD3_k127_2401382_8 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000005984 95.0
HFD3_k127_2401382_9 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000001864 87.0
HFD3_k127_2407700_0 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
HFD3_k127_2407700_1 Domain of unknown function (DUF4388) - - - 0.0000000001223 71.0
HFD3_k127_2407700_2 Histidine kinase - - - 0.000000001022 68.0
HFD3_k127_2407700_3 gag-polyprotein putative aspartyl protease - - - 0.000001907 53.0
HFD3_k127_2441288_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 9.543e-199 634.0
HFD3_k127_2441288_1 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 321.0
HFD3_k127_2441288_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K18100 - - 0.0000000000000000000000000000000000000000000000000000000000000422 225.0
HFD3_k127_2441288_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000001061 165.0
HFD3_k127_2441288_4 Nitrate ABC transporter substrate-binding protein K02051 - - 0.00000000009084 73.0
HFD3_k127_2453053_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 477.0
HFD3_k127_2453053_1 Polysulphide reductase, NrfD K04015 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0001228 47.0
HFD3_k127_2453053_2 COG1977 Molybdopterin converting factor, small subunit K03636 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 - 0.0009685 48.0
HFD3_k127_2473151_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.0 1017.0
HFD3_k127_2473151_1 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.356e-268 855.0
HFD3_k127_2473151_10 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
HFD3_k127_2473151_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 292.0
HFD3_k127_2473151_12 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
HFD3_k127_2473151_13 DMSO reductase anchor subunit (DmsC) - - - 0.00000000000000000000000000000000000000000000000009622 189.0
HFD3_k127_2473151_14 Nitrate reductase delta subunit - - - 0.000000000000000006633 92.0
HFD3_k127_2473151_15 ABC transporter (Periplasmic binding protein) K02051 - - 0.000000001596 70.0
HFD3_k127_2473151_16 PFAM Tetratricopeptide repeat - - - 0.000008071 55.0
HFD3_k127_2473151_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.776e-253 808.0
HFD3_k127_2473151_3 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 6.001e-236 759.0
HFD3_k127_2473151_4 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 483.0
HFD3_k127_2473151_5 4Fe-4S dicluster domain K17048,K17051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
HFD3_k127_2473151_6 Belongs to the UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 436.0
HFD3_k127_2473151_7 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 357.0
HFD3_k127_2473151_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 353.0
HFD3_k127_2473151_9 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HFD3_k127_2477282_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 479.0
HFD3_k127_2477282_1 - - - - 0.00000000000000000000000000000000000005326 150.0
HFD3_k127_2477282_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000005942 130.0
HFD3_k127_2477282_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000002179 78.0
HFD3_k127_2477282_4 e3 binding domain K00658 - 2.3.1.61 0.000000000001378 73.0
HFD3_k127_2477282_5 Protein of unknown function (DUF1232) - - - 0.00000004992 58.0
HFD3_k127_2499293_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000001491 192.0
HFD3_k127_2499293_1 Pfam Amidohydrolase K07045 - - 0.000000009442 61.0
HFD3_k127_250606_0 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA K18383 - 4.1.2.41,4.2.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 399.0
HFD3_k127_250606_1 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000001308 213.0
HFD3_k127_250606_2 ABC transporter K02049 - - 0.000000000000000000000005787 106.0
HFD3_k127_250606_3 NMT1/THI5 like K02051 - - 0.00000000000000000000001057 113.0
HFD3_k127_2508565_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.297e-195 627.0
HFD3_k127_2508565_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 309.0
HFD3_k127_2508565_2 TRAP transporter, solute receptor (TAXI family K01207,K07080 - 3.2.1.52 0.00000000000000000000000000000000000005942 155.0
HFD3_k127_2508565_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000001253 116.0
HFD3_k127_2508565_4 - - - - 0.0001298 49.0
HFD3_k127_250930_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.011e-293 906.0
HFD3_k127_250930_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001491 253.0
HFD3_k127_250930_2 Domain of unknown function (DUF1989) - - - 0.0000000000000000000000000000009818 131.0
HFD3_k127_250930_4 PFAM S23 ribosomal protein - - - 0.000000000004048 67.0
HFD3_k127_250930_5 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000001896 59.0
HFD3_k127_250930_6 glutathione-disulfide reductase activity K00383 - 1.8.1.7 0.0000003526 53.0
HFD3_k127_2522362_0 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 3.822e-283 886.0
HFD3_k127_2522362_1 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 524.0
HFD3_k127_2522362_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000003854 198.0
HFD3_k127_2522362_11 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000004174 154.0
HFD3_k127_2522362_13 Polysaccharide deacetylase - - - 0.0000000000000000000000007696 106.0
HFD3_k127_2522362_14 peptidase M48, Ste24p - - - 0.00000000000000002774 87.0
HFD3_k127_2522362_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000009833 81.0
HFD3_k127_2522362_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 494.0
HFD3_k127_2522362_3 Type I secretion system ABC transporter, HlyB family K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 518.0
HFD3_k127_2522362_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 386.0
HFD3_k127_2522362_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 378.0
HFD3_k127_2522362_6 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 312.0
HFD3_k127_2522362_7 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 305.0
HFD3_k127_2522362_8 abc transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 291.0
HFD3_k127_2522362_9 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001432 207.0
HFD3_k127_2526070_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 348.0
HFD3_k127_2526070_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001004 235.0
HFD3_k127_2526070_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
HFD3_k127_2526070_3 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000005509 192.0
HFD3_k127_2528033_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 430.0
HFD3_k127_2528033_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 321.0
HFD3_k127_2528033_2 Peptidase family S51 K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001126 277.0
HFD3_k127_2528033_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000002829 185.0
HFD3_k127_2547777_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002776 273.0
HFD3_k127_2547777_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005485 228.0
HFD3_k127_2547777_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000009057 190.0
HFD3_k127_2547777_3 Pkd domain containing protein - - - 0.0000000004143 63.0
HFD3_k127_2568165_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.615e-212 667.0
HFD3_k127_2568165_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 445.0
HFD3_k127_2568165_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
HFD3_k127_2568165_4 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000001205 198.0
HFD3_k127_2568165_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000993 134.0
HFD3_k127_2568165_6 - - - - 0.0000000000000001889 81.0
HFD3_k127_2568165_7 - - - - 0.00000000000000522 78.0
HFD3_k127_2568165_8 Transcription factor zinc-finger K09981 - - 0.0000000000002072 74.0
HFD3_k127_2591783_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 498.0
HFD3_k127_2591783_1 Sugar (and other) transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 370.0
HFD3_k127_2591783_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 358.0
HFD3_k127_2591783_3 DMSO reductase, iron-sulfur subunit K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001325 273.0
HFD3_k127_2591783_4 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000002193 206.0
HFD3_k127_2591783_5 COG COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000002139 70.0
HFD3_k127_2591783_6 PFAM YHS domain - - - 0.0000001058 56.0
HFD3_k127_2618540_0 Histidine kinase K07315 - 3.1.3.3 6.356e-202 637.0
HFD3_k127_2618540_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 422.0
HFD3_k127_2618540_10 NmrA family - - - 0.00000004243 62.0
HFD3_k127_2618540_11 AAA ATPase domain - - - 0.0000002747 55.0
HFD3_k127_2618540_12 TIGRFAM methyltransferase FkbM family - - - 0.0001597 52.0
HFD3_k127_2618540_2 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 326.0
HFD3_k127_2618540_3 Transposase mutator type K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 279.0
HFD3_k127_2618540_4 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002717 262.0
HFD3_k127_2618540_5 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000506 250.0
HFD3_k127_2618540_6 SIR2-like domain - - - 0.000000000000000000000000000000000000002938 169.0
HFD3_k127_2618540_7 Lamin Tail Domain K00703,K01990,K02519,K11904 - 2.4.1.21 0.000000000000000000000000000000000000003318 151.0
HFD3_k127_2618540_8 DDE domain K18320 - - 0.000000000000000009929 92.0
HFD3_k127_2618540_9 Pfam:Arch_ATPase K02450 - - 0.000000009491 58.0
HFD3_k127_2646080_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
HFD3_k127_2646080_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
HFD3_k127_2646080_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000002385 179.0
HFD3_k127_2646080_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000251 168.0
HFD3_k127_2646080_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003328 148.0
HFD3_k127_2646080_5 Could be involved in septation K06412 - - 0.00000000000000000000000000000000004412 138.0
HFD3_k127_2659325_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 420.0
HFD3_k127_2659325_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 358.0
HFD3_k127_2659325_10 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.0000000000000004041 87.0
HFD3_k127_2659325_11 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 0.000000000001522 79.0
HFD3_k127_2659325_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000000006951 67.0
HFD3_k127_2659325_13 AMP-binding enzyme K01912 - 6.2.1.30 0.000008862 57.0
HFD3_k127_2659325_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 314.0
HFD3_k127_2659325_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000001591 177.0
HFD3_k127_2659325_4 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000001336 170.0
HFD3_k127_2659325_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000002087 168.0
HFD3_k127_2659325_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000005585 148.0
HFD3_k127_2659325_7 oxidoreductase activity, acting on diphenols and related substances as donors K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.0000000000000000000000000000001328 130.0
HFD3_k127_2659325_8 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000009257 129.0
HFD3_k127_2659325_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000002532 128.0
HFD3_k127_2668746_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1166.0
HFD3_k127_2668746_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 447.0
HFD3_k127_2668746_10 PFAM CBS domain K04767 - - 0.000000000000000000001091 102.0
HFD3_k127_2668746_11 membrane protein (DUF2078) K08982 - - 0.000000000001952 71.0
HFD3_k127_2668746_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000009179 63.0
HFD3_k127_2668746_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 402.0
HFD3_k127_2668746_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 365.0
HFD3_k127_2668746_4 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000753 280.0
HFD3_k127_2668746_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005119 263.0
HFD3_k127_2668746_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000003275 231.0
HFD3_k127_2668746_7 protein histidine kinase activity K02484,K11206,K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000226 238.0
HFD3_k127_2668746_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000005361 167.0
HFD3_k127_2668746_9 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000001018 132.0
HFD3_k127_2673726_0 Thioesterase domain - - - 1.321e-235 756.0
HFD3_k127_2673726_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 313.0
HFD3_k127_2680881_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 458.0
HFD3_k127_2680881_1 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000005477 168.0
HFD3_k127_2680881_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000001306 149.0
HFD3_k127_2680881_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000548 152.0
HFD3_k127_2680881_4 LysR substrate binding domain - - - 0.00000002396 65.0
HFD3_k127_2680881_5 thiamine-containing compound biosynthetic process K02051 - - 0.0001622 48.0
HFD3_k127_2684126_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 432.0
HFD3_k127_2684126_1 protein conserved in bacteria - - - 0.00000000000000000000000000000001294 136.0
HFD3_k127_2687941_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.31e-301 964.0
HFD3_k127_2687941_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
HFD3_k127_2687941_2 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000002259 207.0
HFD3_k127_2687941_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000001723 192.0
HFD3_k127_2694091_0 Endopeptidase La K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 627.0
HFD3_k127_2694091_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000474 190.0
HFD3_k127_2694091_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000002925 105.0
HFD3_k127_2694091_3 NMT1-like family K02051 - - 0.0000000000000001698 91.0
HFD3_k127_2694091_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000005064 64.0
HFD3_k127_2694091_5 Protein of unknown function (DUF2934) - - - 0.0003354 48.0
HFD3_k127_2695481_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 589.0
HFD3_k127_2695481_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 413.0
HFD3_k127_2695481_10 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000004283 147.0
HFD3_k127_2695481_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000000002688 129.0
HFD3_k127_2695481_12 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000001877 135.0
HFD3_k127_2695481_13 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000016 99.0
HFD3_k127_2695481_14 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000003384 104.0
HFD3_k127_2695481_15 NMT1-like family - - - 0.00000000000003529 83.0
HFD3_k127_2695481_16 Alcohol dehydrogenase GroES-like domain - - - 0.00000000007678 66.0
HFD3_k127_2695481_17 Tetratricopeptide repeat - - - 0.00000005335 64.0
HFD3_k127_2695481_18 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000004603 53.0
HFD3_k127_2695481_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 363.0
HFD3_k127_2695481_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007167 269.0
HFD3_k127_2695481_4 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003651 265.0
HFD3_k127_2695481_5 PFAM Dihydrodipicolinate synthetase K11946,K11949 - 4.1.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000008322 255.0
HFD3_k127_2695481_6 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000000000000000000000000000004286 228.0
HFD3_k127_2695481_7 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000001793 191.0
HFD3_k127_2695481_8 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000004476 191.0
HFD3_k127_2695481_9 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000001082 152.0
HFD3_k127_2697996_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 643.0
HFD3_k127_2697996_1 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 351.0
HFD3_k127_2697996_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005625 291.0
HFD3_k127_2697996_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000006837 218.0
HFD3_k127_2697996_4 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000001797 198.0
HFD3_k127_2697996_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000158 175.0
HFD3_k127_2697996_6 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000512 110.0
HFD3_k127_2697996_7 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000002391 106.0
HFD3_k127_2697996_8 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000003284 91.0
HFD3_k127_2705550_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.145e-230 729.0
HFD3_k127_2705550_1 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 415.0
HFD3_k127_2705550_10 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 347.0
HFD3_k127_2705550_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 321.0
HFD3_k127_2705550_12 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 323.0
HFD3_k127_2705550_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
HFD3_k127_2705550_14 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
HFD3_k127_2705550_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 307.0
HFD3_k127_2705550_16 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
HFD3_k127_2705550_17 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
HFD3_k127_2705550_18 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 283.0
HFD3_k127_2705550_19 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000535 273.0
HFD3_k127_2705550_2 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 398.0
HFD3_k127_2705550_20 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HFD3_k127_2705550_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000005065 233.0
HFD3_k127_2705550_22 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000007836 221.0
HFD3_k127_2705550_23 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000003704 203.0
HFD3_k127_2705550_24 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000003499 199.0
HFD3_k127_2705550_25 HD domain - - - 0.00000000000000000000000000000000000000000000007185 179.0
HFD3_k127_2705550_26 carbohydrate metabolic process K21014 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681 2.8.2.37 0.00000000000000000000000000000000000000000233 165.0
HFD3_k127_2705550_27 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000003251 149.0
HFD3_k127_2705550_29 HD domain - - - 0.00000000000000000000000000000000000003504 162.0
HFD3_k127_2705550_3 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HFD3_k127_2705550_30 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000008499 155.0
HFD3_k127_2705550_31 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000001069 152.0
HFD3_k127_2705550_32 polysaccharide deacetylase - - - 0.0000000000000000000000000000002821 136.0
HFD3_k127_2705550_33 - - - - 0.0000000000000000000000000002826 124.0
HFD3_k127_2705550_34 - - - - 0.0000000000000000001123 100.0
HFD3_k127_2705550_35 NAD(P)H-binding K18981 - 1.1.1.203 0.0000000000000000003897 96.0
HFD3_k127_2705550_36 - - - - 0.00000000000000009724 90.0
HFD3_k127_2705550_37 Iron-sulfur cluster-binding domain - - - 0.0000000000001606 81.0
HFD3_k127_2705550_38 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000005585 79.0
HFD3_k127_2705550_4 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 390.0
HFD3_k127_2705550_5 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 388.0
HFD3_k127_2705550_6 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 394.0
HFD3_k127_2705550_7 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 383.0
HFD3_k127_2705550_8 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 378.0
HFD3_k127_2705550_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 350.0
HFD3_k127_2706140_0 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000004336 245.0
HFD3_k127_2706140_1 PFAM response regulator receiver - - - 0.000000000000004388 85.0
HFD3_k127_2706140_2 Receptor family ligand binding region K01999 - - 0.00000000002129 67.0
HFD3_k127_2706140_3 - - - - 0.00000001304 59.0
HFD3_k127_2778078_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 8.046e-271 862.0
HFD3_k127_2778078_1 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.093e-260 833.0
HFD3_k127_2778078_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 1.024e-259 829.0
HFD3_k127_2778078_3 PFAM YHS domain - - - 0.0000000007431 61.0
HFD3_k127_2782754_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 1.766e-194 616.0
HFD3_k127_2782754_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 508.0
HFD3_k127_2782754_2 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 396.0
HFD3_k127_2782754_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 354.0
HFD3_k127_2782754_4 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000007301 230.0
HFD3_k127_2782754_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000002944 94.0
HFD3_k127_2796060_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 4.487e-209 671.0
HFD3_k127_2796060_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 2.546e-203 648.0
HFD3_k127_2796060_10 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000153 103.0
HFD3_k127_2796060_11 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000004981 89.0
HFD3_k127_2796060_2 Cysteine-rich domain K11473,K21834 - - 4.775e-197 634.0
HFD3_k127_2796060_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 355.0
HFD3_k127_2796060_4 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003962 262.0
HFD3_k127_2796060_5 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000009784 247.0
HFD3_k127_2796060_6 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000002928 248.0
HFD3_k127_2796060_7 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000002073 226.0
HFD3_k127_2796060_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000003289 201.0
HFD3_k127_2796060_9 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000002547 106.0
HFD3_k127_2838948_0 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 479.0
HFD3_k127_2838948_1 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001535 285.0
HFD3_k127_2838948_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009685 276.0
HFD3_k127_2838948_3 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000000000007429 87.0
HFD3_k127_2838948_4 NMT1-like family K02051 - - 0.00006822 54.0
HFD3_k127_2849479_0 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001623 248.0
HFD3_k127_2849479_1 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000003169 218.0
HFD3_k127_2849479_2 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000007472 141.0
HFD3_k127_2849479_3 Enoyl-CoA hydratase/isomerase K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000297 138.0
HFD3_k127_2849479_4 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000003805 126.0
HFD3_k127_2849479_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000002731 95.0
HFD3_k127_2849479_6 NMT1-like family K02051 - - 0.00000000000004364 83.0
HFD3_k127_2849479_7 ABC transporter substrate-binding protein K02051 - - 0.00000000000004987 83.0
HFD3_k127_2849479_8 class II Aldolase - - - 0.000002271 54.0
HFD3_k127_2849479_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0003425 52.0
HFD3_k127_2856244_0 FAD binding domain K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 544.0
HFD3_k127_2856244_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001162 272.0
HFD3_k127_2856244_2 NMT1-like family - - - 0.00000000000000000000000000000006418 137.0
HFD3_k127_2856244_3 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000007377 132.0
HFD3_k127_2856244_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000003499 66.0
HFD3_k127_2877137_0 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
HFD3_k127_2877137_1 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 280.0
HFD3_k127_2877137_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002518 280.0
HFD3_k127_2877137_3 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000000000000000000000001091 194.0
HFD3_k127_2877137_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000005347 129.0
HFD3_k127_2911624_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.837e-251 784.0
HFD3_k127_2911624_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 543.0
HFD3_k127_2911624_10 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000009238 196.0
HFD3_k127_2911624_11 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000004351 181.0
HFD3_k127_2911624_12 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000006083 186.0
HFD3_k127_2911624_13 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000002738 164.0
HFD3_k127_2911624_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000002018 102.0
HFD3_k127_2911624_15 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000006985 104.0
HFD3_k127_2911624_16 Phosphotransferase System K11189 - - 0.000000000000000000009116 96.0
HFD3_k127_2911624_17 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000009321 93.0
HFD3_k127_2911624_18 OstA-like protein K09774 - - 0.00000000000005054 79.0
HFD3_k127_2911624_19 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000101 67.0
HFD3_k127_2911624_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 454.0
HFD3_k127_2911624_20 Lipopolysaccharide-assembly, LptC-related - - - 0.0001459 51.0
HFD3_k127_2911624_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 438.0
HFD3_k127_2911624_4 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 387.0
HFD3_k127_2911624_5 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 384.0
HFD3_k127_2911624_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 357.0
HFD3_k127_2911624_7 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 309.0
HFD3_k127_2911624_8 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 307.0
HFD3_k127_2911624_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008856 276.0
HFD3_k127_2917203_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 465.0
HFD3_k127_2917203_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 377.0
HFD3_k127_2917203_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000003914 158.0
HFD3_k127_2917203_3 spore germination - - - 0.000000000000000000000000000000000000000004991 167.0
HFD3_k127_2917203_4 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.00000000000000000000000000344 117.0
HFD3_k127_2917203_5 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000221 49.0
HFD3_k127_2928124_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 364.0
HFD3_k127_2928124_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 337.0
HFD3_k127_2928124_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 291.0
HFD3_k127_2928124_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005699 280.0
HFD3_k127_2928124_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000001136 194.0
HFD3_k127_2928124_5 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000003466 144.0
HFD3_k127_2928124_6 VIT family - - - 0.0000000000000000000000000000007431 131.0
HFD3_k127_2928124_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000008206 70.0
HFD3_k127_2936270_0 PIN domain - - - 0.0000000000000000000000000000000000000000000000004308 177.0
HFD3_k127_2936270_1 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000008645 104.0
HFD3_k127_2936270_2 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000002056 76.0
HFD3_k127_2936270_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000001643 78.0
HFD3_k127_2936270_4 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.000000006635 61.0
HFD3_k127_2936270_5 ABC transporter K02051 - - 0.000000563 61.0
HFD3_k127_2936270_6 TIGRFAM transcriptional regulator, AbrB family - - - 0.00002496 49.0
HFD3_k127_2979607_0 exo-alpha-(2->6)-sialidase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 630.0
HFD3_k127_2979607_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 494.0
HFD3_k127_2979607_10 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000236 269.0
HFD3_k127_2979607_11 KR domain K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000001727 229.0
HFD3_k127_2979607_12 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000002469 211.0
HFD3_k127_2979607_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000006867 194.0
HFD3_k127_2979607_14 reductase - - - 0.0000000001098 68.0
HFD3_k127_2979607_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 429.0
HFD3_k127_2979607_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 418.0
HFD3_k127_2979607_4 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 384.0
HFD3_k127_2979607_5 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
HFD3_k127_2979607_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
HFD3_k127_2979607_7 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 292.0
HFD3_k127_2979607_8 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 272.0
HFD3_k127_2979607_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001461 265.0
HFD3_k127_298839_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.23e-266 841.0
HFD3_k127_298839_1 - - - - 0.000000000000000008728 91.0
HFD3_k127_298839_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000606 86.0
HFD3_k127_298839_3 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000006771 77.0
HFD3_k127_298839_4 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00002815 49.0
HFD3_k127_3039638_0 Phosphoglucose isomerase K00616,K13810 - 2.2.1.2,5.3.1.9 8.735e-309 971.0
HFD3_k127_3039638_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 600.0
HFD3_k127_3039638_10 Putative zinc-finger - - - 0.000002267 58.0
HFD3_k127_3039638_11 monooxygenase activity - - - 0.00001888 50.0
HFD3_k127_3039638_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
HFD3_k127_3039638_3 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 359.0
HFD3_k127_3039638_4 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
HFD3_k127_3039638_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 311.0
HFD3_k127_3039638_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
HFD3_k127_3039638_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000003163 214.0
HFD3_k127_3039638_8 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000004067 141.0
HFD3_k127_3039638_9 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000001604 73.0
HFD3_k127_3053877_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 510.0
HFD3_k127_3053877_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 377.0
HFD3_k127_3053877_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000002208 154.0
HFD3_k127_3053877_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000827 137.0
HFD3_k127_3053877_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000002768 75.0
HFD3_k127_308635_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 481.0
HFD3_k127_308635_1 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 298.0
HFD3_k127_308635_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000001866 52.0
HFD3_k127_308635_2 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000004054 175.0
HFD3_k127_308635_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000006791 177.0
HFD3_k127_308635_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000002007 151.0
HFD3_k127_308635_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019295,GO:0019296,GO:0044237,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0050545,GO:0051186,GO:0051188,GO:0071704,GO:1901576 4.1.1.79 0.000000000000000000000000000001178 128.0
HFD3_k127_308635_6 PFAM Glutathione S-transferase, N-terminal K00799 - 2.5.1.18 0.0000000000000000000000000002232 122.0
HFD3_k127_308635_7 oxidation-reduction process - - - 0.00000000000000000000000001222 113.0
HFD3_k127_308635_8 Redoxin - - - 0.0000001051 57.0
HFD3_k127_308635_9 Cytochrome C' - - - 0.0000001793 57.0
HFD3_k127_3114054_0 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000001096 172.0
HFD3_k127_3114054_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000001501 166.0
HFD3_k127_3114054_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000078 133.0
HFD3_k127_3114054_3 beta-lactamase domain protein K05555 - - 0.0000000000000000000000000000002745 134.0
HFD3_k127_3114054_4 AMP-binding enzyme C-terminal domain K12424 - 6.2.1.50 0.000000000001243 70.0
HFD3_k127_3123056_0 ornithine cyclodeaminase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 344.0
HFD3_k127_3123056_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000005317 219.0
HFD3_k127_3123056_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000001847 214.0
HFD3_k127_3123056_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000001501 215.0
HFD3_k127_3123056_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004157 217.0
HFD3_k127_3123056_5 peptidase - - - 0.000000000000000000000000000000000000000000000000000003155 205.0
HFD3_k127_3123056_6 NMT1-like family K02051 - - 0.00000000000000000000000001789 126.0
HFD3_k127_3123056_7 Transglycosylase SLT domain K06381,K08309 - - 0.0000000000000000000123 94.0
HFD3_k127_3136102_0 Domain of unknown function (DUF3552) K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 608.0
HFD3_k127_3136102_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 488.0
HFD3_k127_3136102_2 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 302.0
HFD3_k127_3136102_3 - - - - 0.00000000000000000000000005675 108.0
HFD3_k127_3136102_7 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000002243 66.0
HFD3_k127_3144413_0 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 509.0
HFD3_k127_3144413_1 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 493.0
HFD3_k127_3144413_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 320.0
HFD3_k127_3144413_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 317.0
HFD3_k127_3144413_4 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 306.0
HFD3_k127_3144413_5 beta-N-acetylglucosaminidase K01197,K15719 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000002345 239.0
HFD3_k127_3144413_6 Sulfatase-modifying factor enzyme 1 - - - 0.000000000005642 70.0
HFD3_k127_3164700_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 590.0
HFD3_k127_3164700_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 405.0
HFD3_k127_3164700_2 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 298.0
HFD3_k127_3164700_3 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000001681 196.0
HFD3_k127_3164700_4 signal transduction histidine kinase - - - 0.0000000000000000004575 98.0
HFD3_k127_3164700_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000009775 63.0
HFD3_k127_3176328_0 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 507.0
HFD3_k127_3176328_1 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002478 277.0
HFD3_k127_3176328_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005002 263.0
HFD3_k127_3176328_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000003094 194.0
HFD3_k127_3176328_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000005028 126.0
HFD3_k127_3185744_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000002407 190.0
HFD3_k127_3185744_1 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000009844 122.0
HFD3_k127_3185744_2 F420H(2)-dependent quinone reductase - - - 0.000000000000000000004947 100.0
HFD3_k127_3187000_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.439e-308 957.0
HFD3_k127_3187000_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 448.0
HFD3_k127_3187000_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 401.0
HFD3_k127_3187000_3 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 239.0
HFD3_k127_3187000_4 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000001679 224.0
HFD3_k127_3187000_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000004495 142.0
HFD3_k127_3187000_6 ACT domain - - - 0.000000000000000000000000000000005637 132.0
HFD3_k127_3187000_7 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000008532 93.0
HFD3_k127_3187000_8 Universal stress protein K06149 - - 0.0000000000000000002788 94.0
HFD3_k127_3187000_9 AAA domain - - - 0.00000009592 61.0
HFD3_k127_3192689_0 Pfam:KaiC K08482 - - 9.986e-209 660.0
HFD3_k127_3192689_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 7.298e-199 641.0
HFD3_k127_3192689_10 - - - - 0.0000000000000000000000008516 110.0
HFD3_k127_3192689_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000546 102.0
HFD3_k127_3192689_12 cheY-homologous receiver domain - - - 0.0000000000000000000518 94.0
HFD3_k127_3192689_13 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000001283 66.0
HFD3_k127_3192689_14 Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.000003222 49.0
HFD3_k127_3192689_15 - - - - 0.0003189 45.0
HFD3_k127_3192689_2 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
HFD3_k127_3192689_3 Histidine kinase K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 297.0
HFD3_k127_3192689_4 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
HFD3_k127_3192689_5 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
HFD3_k127_3192689_6 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000002917 181.0
HFD3_k127_3192689_7 KaiB K08481 - - 0.00000000000000000000000000000000000001088 147.0
HFD3_k127_3192689_8 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000006828 153.0
HFD3_k127_3192689_9 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000004738 110.0
HFD3_k127_3196038_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1122.0
HFD3_k127_3196038_1 Cytochrome c - - - 1.512e-219 712.0
HFD3_k127_3196038_10 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000216 201.0
HFD3_k127_3196038_11 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000005099 196.0
HFD3_k127_3196038_12 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000004321 186.0
HFD3_k127_3196038_13 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000004984 179.0
HFD3_k127_3196038_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000002767 171.0
HFD3_k127_3196038_15 GAF domain K02482 - 2.7.13.3 0.00000000000000000000000000008177 127.0
HFD3_k127_3196038_16 Class II Aldolase and Adducin N-terminal domain K10622 - - 0.00000000000000000000000001285 118.0
HFD3_k127_3196038_17 RTX-III toxin determinant D of Gammaproteobacteria UniRef RepID RTX3D_ACTPL K11003 - - 0.0000000000001104 79.0
HFD3_k127_3196038_18 - - - - 0.0000000000001883 74.0
HFD3_k127_3196038_19 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000001089 66.0
HFD3_k127_3196038_2 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 421.0
HFD3_k127_3196038_20 SPTR Transposase, IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.000000006951 56.0
HFD3_k127_3196038_21 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.00002939 48.0
HFD3_k127_3196038_22 Amidohydrolase K10220 - 4.2.1.83 0.0008989 42.0
HFD3_k127_3196038_3 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 357.0
HFD3_k127_3196038_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 322.0
HFD3_k127_3196038_5 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 304.0
HFD3_k127_3196038_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002795 279.0
HFD3_k127_3196038_7 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000003204 255.0
HFD3_k127_3196038_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004051 258.0
HFD3_k127_3196038_9 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002252 251.0
HFD3_k127_3217839_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 396.0
HFD3_k127_3217839_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001458 211.0
HFD3_k127_3217839_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000003398 196.0
HFD3_k127_3217839_3 - - - - 0.0000000000000000000000000007024 131.0
HFD3_k127_3217839_4 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000001124 94.0
HFD3_k127_3217839_5 Transmembrane and - - - 0.00000000000006194 77.0
HFD3_k127_3230451_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 562.0
HFD3_k127_3230451_1 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 492.0
HFD3_k127_3230451_2 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 479.0
HFD3_k127_3230451_3 KaiC - - - 0.0000000000000000000000000000008263 130.0
HFD3_k127_3230451_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0002798 43.0
HFD3_k127_3246395_0 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 411.0
HFD3_k127_3246395_1 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000005765 147.0
HFD3_k127_3246395_2 methyltransferase - - - 0.00000000000000000000000000003214 119.0
HFD3_k127_3246395_3 NMT1-like family K02051 - - 0.000000738 61.0
HFD3_k127_324683_0 protein conserved in bacteria K07793 - - 4.238e-219 689.0
HFD3_k127_324683_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000001189 224.0
HFD3_k127_324683_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000001307 192.0
HFD3_k127_324683_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000002081 180.0
HFD3_k127_324683_4 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000235 156.0
HFD3_k127_324683_5 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000007075 120.0
HFD3_k127_324683_6 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000001047 98.0
HFD3_k127_3296409_0 Belongs to the ompA family K03640 - - 0.000000000000000000000000000002824 128.0
HFD3_k127_3307274_0 - - - - 0.0000000000000000000000000004461 121.0
HFD3_k127_3307274_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000004673 49.0
HFD3_k127_3312262_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1208.0
HFD3_k127_3312262_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 301.0
HFD3_k127_3312262_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003417 249.0
HFD3_k127_3312262_3 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000001038 143.0
HFD3_k127_3317414_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.189e-316 998.0
HFD3_k127_3317414_1 TRCF K03723 - - 2.49e-301 964.0
HFD3_k127_3317414_10 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000003221 122.0
HFD3_k127_3317414_11 Belongs to the ompA family - - - 0.000000000000000000000006075 111.0
HFD3_k127_3317414_13 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 0.00000000000009586 71.0
HFD3_k127_3317414_14 Domain of unknown function (DUF309) K09763 - - 0.0000000003016 65.0
HFD3_k127_3317414_15 Belongs to the ompA family - - - 0.0002151 49.0
HFD3_k127_3317414_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 1.038e-226 728.0
HFD3_k127_3317414_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 542.0
HFD3_k127_3317414_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 525.0
HFD3_k127_3317414_5 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 332.0
HFD3_k127_3317414_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001223 228.0
HFD3_k127_3317414_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000002547 188.0
HFD3_k127_3317414_8 FAD binding domain K07077 - - 0.000000000000000000000000000000000000000004714 172.0
HFD3_k127_3317414_9 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000002727 160.0
HFD3_k127_3327882_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 2073.0
HFD3_k127_3327882_1 Sigma-54 interaction domain K07714,K07715 - - 1.844e-194 616.0
HFD3_k127_3327882_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003701 275.0
HFD3_k127_3327882_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000003303 75.0
HFD3_k127_3327882_4 - - - - 0.00000005359 57.0
HFD3_k127_3339675_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.068e-256 812.0
HFD3_k127_3339675_1 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 576.0
HFD3_k127_3339675_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
HFD3_k127_3339675_11 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000001255 221.0
HFD3_k127_3339675_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001858 199.0
HFD3_k127_3339675_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000001206 184.0
HFD3_k127_3339675_14 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001446 172.0
HFD3_k127_3339675_15 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000001224 162.0
HFD3_k127_3339675_16 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000001276 143.0
HFD3_k127_3339675_17 TatD related DNase K03424 - - 0.00000000000009192 74.0
HFD3_k127_3339675_18 Tripartite tricarboxylate transporter family receptor - - - 0.0007555 45.0
HFD3_k127_3339675_2 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 542.0
HFD3_k127_3339675_3 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 516.0
HFD3_k127_3339675_4 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 465.0
HFD3_k127_3339675_5 carbohydrate transport K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 415.0
HFD3_k127_3339675_6 ATPase activity K10111,K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 362.0
HFD3_k127_3339675_7 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
HFD3_k127_3339675_8 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 308.0
HFD3_k127_3339675_9 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000003365 233.0
HFD3_k127_3367403_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 414.0
HFD3_k127_3367403_1 Hydantoin racemase K16841 - 5.1.99.3 0.0000000005097 70.0
HFD3_k127_3374427_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000001878 207.0
HFD3_k127_3374427_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000268 173.0
HFD3_k127_3374427_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000001616 134.0
HFD3_k127_3374427_3 Domain of unknown function (DUF4926) - - - 0.000000000000003283 78.0
HFD3_k127_3374427_4 NMT1/THI5 like K02051 - - 0.000000003174 68.0
HFD3_k127_3374427_5 AMP-binding enzyme C-terminal domain K00666 - - 0.0000002931 52.0
HFD3_k127_3374427_6 Serine aminopeptidase, S33 K16050 - 3.7.1.17 0.000132 48.0
HFD3_k127_3374427_7 Alpha/beta hydrolase family - - - 0.0008264 43.0
HFD3_k127_3386619_0 Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 474.0
HFD3_k127_3386619_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 423.0
HFD3_k127_3386619_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 375.0
HFD3_k127_3386619_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003426 282.0
HFD3_k127_3386619_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - 0.000000000000000000000000000000002079 137.0
HFD3_k127_3386619_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000006642 141.0
HFD3_k127_3386619_6 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000005422 132.0
HFD3_k127_3386619_7 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000002013 104.0
HFD3_k127_3386619_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000001824 88.0
HFD3_k127_3386619_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000002176 73.0
HFD3_k127_3410312_0 Tripartite tricarboxylate transporter TctA family - - - 1.214e-206 654.0
HFD3_k127_3410312_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 348.0
HFD3_k127_3410312_2 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 344.0
HFD3_k127_3410312_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000003299 153.0
HFD3_k127_3410312_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000002264 117.0
HFD3_k127_3410312_6 PFAM Cupin 2, conserved barrel domain protein - - - 0.0007303 48.0
HFD3_k127_3461443_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1028.0
HFD3_k127_3461443_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.377e-288 907.0
HFD3_k127_3461443_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 583.0
HFD3_k127_3461443_3 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 389.0
HFD3_k127_3461443_4 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000002192 213.0
HFD3_k127_3461443_5 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000113 114.0
HFD3_k127_3484955_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 567.0
HFD3_k127_3484955_1 Thioredoxin-like K02199,K03671 - - 0.0000000000000000000000000000000000000000000000000002701 191.0
HFD3_k127_3484955_2 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000201 171.0
HFD3_k127_3484955_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000005251 133.0
HFD3_k127_3484955_4 subunit of a heme lyase K02198,K02200 - - 0.000000000002803 71.0
HFD3_k127_3510811_0 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 451.0
HFD3_k127_3510811_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 371.0
HFD3_k127_3510811_2 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 377.0
HFD3_k127_3510811_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 311.0
HFD3_k127_3510811_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 283.0
HFD3_k127_3510811_5 PFAM response regulator receiver K07657,K07659,K07664,K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
HFD3_k127_3510811_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000004923 186.0
HFD3_k127_3510811_7 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000005058 164.0
HFD3_k127_3510811_8 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.0000000000002927 74.0
HFD3_k127_3544901_0 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 475.0
HFD3_k127_3544901_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000002161 203.0
HFD3_k127_3544901_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000008204 154.0
HFD3_k127_3544901_3 twitching motility protein K02669,K12203 - - 0.000000000000000000000000000000002619 130.0
HFD3_k127_3693649_0 ATPases associated with a variety of cellular activities K02003,K05685 - - 1.72e-258 812.0
HFD3_k127_3693649_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 379.0
HFD3_k127_3693649_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 346.0
HFD3_k127_3693649_3 NMT1-like family - - - 0.0000000000000000001472 100.0
HFD3_k127_3732546_0 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 516.0
HFD3_k127_3732546_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 364.0
HFD3_k127_3732546_2 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 366.0
HFD3_k127_3732546_3 Protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 313.0
HFD3_k127_3732546_4 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004997 287.0
HFD3_k127_3732546_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000683 178.0
HFD3_k127_3732546_6 CAAX protease self-immunity - - - 0.000000000000000000000000000000004759 139.0
HFD3_k127_3747312_0 PFAM sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 458.0
HFD3_k127_3747312_1 Bacterial regulatory protein, Fis family K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 307.0
HFD3_k127_3747312_2 acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 308.0
HFD3_k127_3747312_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006953 268.0
HFD3_k127_3747312_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000002627 177.0
HFD3_k127_3747312_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000002659 108.0
HFD3_k127_3747312_6 Integrase core domain - - - 0.000000000000004123 78.0
HFD3_k127_3747312_7 iron ion homeostasis K02012 - - 0.000001907 53.0
HFD3_k127_3753447_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 541.0
HFD3_k127_3753447_1 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 532.0
HFD3_k127_3753447_10 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000000000000000001607 177.0
HFD3_k127_3753447_11 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000004054 175.0
HFD3_k127_3753447_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000008483 166.0
HFD3_k127_3753447_13 Circadian clock protein KaiC K08482 - - 0.0000000000000000000000000000000000009808 147.0
HFD3_k127_3753447_14 Belongs to the HSP15 family K04762 - - 0.00000000000000000000000000000000001038 139.0
HFD3_k127_3753447_15 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000002694 132.0
HFD3_k127_3753447_16 Transcriptional regulator - - - 0.0000000000000000000000000000008411 127.0
HFD3_k127_3753447_17 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000003 130.0
HFD3_k127_3753447_18 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000003156 121.0
HFD3_k127_3753447_19 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000001812 119.0
HFD3_k127_3753447_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 499.0
HFD3_k127_3753447_20 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000005642 113.0
HFD3_k127_3753447_21 Chemotaxis protein CheY K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000001902 104.0
HFD3_k127_3753447_22 Belongs to the UPF0145 family - - - 0.000000000000000003317 86.0
HFD3_k127_3753447_23 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.000000000000000006205 83.0
HFD3_k127_3753447_24 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000001214 72.0
HFD3_k127_3753447_25 regulation of response to stimulus K14767,K16175 - - 0.0002803 55.0
HFD3_k127_3753447_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 381.0
HFD3_k127_3753447_4 CHASE3 domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 338.0
HFD3_k127_3753447_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 324.0
HFD3_k127_3753447_6 CHASE3 domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 307.0
HFD3_k127_3753447_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000006961 264.0
HFD3_k127_3753447_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
HFD3_k127_3753447_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000001534 236.0
HFD3_k127_3761166_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 8.344e-273 852.0
HFD3_k127_3761166_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 463.0
HFD3_k127_3761166_10 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.000000000000000000000000006703 112.0
HFD3_k127_3761166_11 Belongs to the precorrin methyltransferase family K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000059 104.0
HFD3_k127_3761166_12 COGs COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000004283 64.0
HFD3_k127_3761166_13 - - - - 0.000000309 55.0
HFD3_k127_3761166_14 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0006973 45.0
HFD3_k127_3761166_2 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 426.0
HFD3_k127_3761166_3 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 351.0
HFD3_k127_3761166_4 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002972 283.0
HFD3_k127_3761166_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
HFD3_k127_3761166_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000006648 192.0
HFD3_k127_3761166_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001932 199.0
HFD3_k127_3761166_8 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000000000000000000000000005059 151.0
HFD3_k127_3761166_9 xaa-pro dipeptidase K01271 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000001445 136.0
HFD3_k127_3767960_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 8.125e-226 731.0
HFD3_k127_3767960_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 527.0
HFD3_k127_3767960_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 366.0
HFD3_k127_3767960_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 330.0
HFD3_k127_3767960_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
HFD3_k127_3767960_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000001588 248.0
HFD3_k127_3767960_6 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000006304 233.0
HFD3_k127_3767960_7 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000682 205.0
HFD3_k127_3767960_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000006448 200.0
HFD3_k127_37706_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1245.0
HFD3_k127_37706_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 507.0
HFD3_k127_37706_10 Yip1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
HFD3_k127_37706_11 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002007 211.0
HFD3_k127_37706_12 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000002685 209.0
HFD3_k127_37706_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000007079 191.0
HFD3_k127_37706_14 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000002539 152.0
HFD3_k127_37706_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000001391 131.0
HFD3_k127_37706_16 - - - - 0.0000000000000000000000000000001503 126.0
HFD3_k127_37706_18 Membrane - - - 0.00000000000000000000000000003749 121.0
HFD3_k127_37706_19 Cupin domain K11312 - - 0.000000000000000000000000004259 113.0
HFD3_k127_37706_2 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 375.0
HFD3_k127_37706_20 - - - - 0.00000000000002333 76.0
HFD3_k127_37706_21 PLD-like domain - - - 0.0000000000002584 73.0
HFD3_k127_37706_22 coenzyme F390 K01912 - 6.2.1.30 0.0000000005531 64.0
HFD3_k127_37706_23 Putative transposase - - - 0.00000002001 59.0
HFD3_k127_37706_24 - - - - 0.00000002198 61.0
HFD3_k127_37706_25 methyltransferase - - - 0.0000000318 64.0
HFD3_k127_37706_26 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.0004021 47.0
HFD3_k127_37706_3 iron assimilation K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 363.0
HFD3_k127_37706_4 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
HFD3_k127_37706_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 292.0
HFD3_k127_37706_6 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
HFD3_k127_37706_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001056 241.0
HFD3_k127_37706_8 epimerase K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
HFD3_k127_37706_9 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000003659 243.0
HFD3_k127_3778518_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000003443 230.0
HFD3_k127_3778518_1 - - - - 0.0000000000000000000000000000000000000000000000006601 180.0
HFD3_k127_3778518_2 DNA polymerase III, delta' K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000001312 182.0
HFD3_k127_3778518_3 SMART phospholipase D Transphosphatidylase - - - 0.000000000000000000000000003708 117.0
HFD3_k127_3778518_4 Acyl-CoA dehydrogenase, N-terminal K16173 - 1.3.99.32 0.000000001448 60.0
HFD3_k127_3778518_5 Nucleic acid binding - - - 0.0002018 52.0
HFD3_k127_3803715_0 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 - - 0.000000000000000000000000000000000000000000000000000001602 203.0
HFD3_k127_3803715_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000004806 182.0
HFD3_k127_3803715_2 Domain of unknown function (DUF4124) K08309 - - 0.0000000000000000000000000000000000000005508 156.0
HFD3_k127_3803715_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000002605 153.0
HFD3_k127_3803715_5 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000001578 118.0
HFD3_k127_3803715_6 Domain of unknown function (DUF4410) - - - 0.000000000000001428 86.0
HFD3_k127_3803715_7 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000005262 72.0
HFD3_k127_3803715_8 - - - - 0.0000007245 51.0
HFD3_k127_3805579_0 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 569.0
HFD3_k127_3805579_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 423.0
HFD3_k127_3805579_2 PFAM Peptidase M16 K07263 - - 0.00000000000000000009413 91.0
HFD3_k127_3805579_3 NMT1-like family K02051 - - 0.00000000000000003462 93.0
HFD3_k127_3805579_4 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000008532 63.0
HFD3_k127_3805579_5 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0003881 44.0
HFD3_k127_3809036_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 549.0
HFD3_k127_3809036_1 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000286 141.0
HFD3_k127_3809036_2 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000893 139.0
HFD3_k127_3809036_3 Protein of unknown function (DUF433) - - - 0.000000000002146 70.0
HFD3_k127_3809036_4 Carboxymuconolactone decarboxylase family - - - 0.00000000006736 65.0
HFD3_k127_3809036_5 Carboxymuconolactone decarboxylase family - - - 0.000000003931 61.0
HFD3_k127_3809036_6 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.00002639 50.0
HFD3_k127_3809036_7 NMT1-like family K02051 - - 0.0001519 53.0
HFD3_k127_38095_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 8.817e-271 857.0
HFD3_k127_38095_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 4.516e-218 707.0
HFD3_k127_38095_10 nitrogen compound transport K02033,K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 346.0
HFD3_k127_38095_11 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 322.0
HFD3_k127_38095_12 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 290.0
HFD3_k127_38095_13 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
HFD3_k127_38095_14 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582,K16201 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
HFD3_k127_38095_15 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002497 255.0
HFD3_k127_38095_16 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
HFD3_k127_38095_17 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000205 237.0
HFD3_k127_38095_18 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000004275 235.0
HFD3_k127_38095_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000006317 231.0
HFD3_k127_38095_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 602.0
HFD3_k127_38095_20 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000001226 198.0
HFD3_k127_38095_21 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000002696 184.0
HFD3_k127_38095_22 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000006728 179.0
HFD3_k127_38095_23 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001394 165.0
HFD3_k127_38095_24 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000377 162.0
HFD3_k127_38095_25 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000007975 111.0
HFD3_k127_38095_26 Transcriptional regulator - - - 0.000000000000000000008876 100.0
HFD3_k127_38095_27 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000001079 82.0
HFD3_k127_38095_3 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 518.0
HFD3_k127_38095_4 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 510.0
HFD3_k127_38095_5 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 501.0
HFD3_k127_38095_6 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 438.0
HFD3_k127_38095_7 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 414.0
HFD3_k127_38095_8 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 423.0
HFD3_k127_38095_9 Creatinase/Prolidase N-terminal domain K15783 - 3.5.4.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
HFD3_k127_3822830_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 2.183e-208 666.0
HFD3_k127_3822830_1 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 368.0
HFD3_k127_3822830_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768,K03320 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001898 254.0
HFD3_k127_3822830_3 Protein of unknown function (DUF2283) - - - 0.000000000000000000003854 102.0
HFD3_k127_3822830_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000001152 96.0
HFD3_k127_3822830_5 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000001309 57.0
HFD3_k127_3822830_6 Excisionase - - - 0.000000146 55.0
HFD3_k127_3822830_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0003677 49.0
HFD3_k127_3832075_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.688e-200 651.0
HFD3_k127_3832075_1 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003067 246.0
HFD3_k127_3832075_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000006279 214.0
HFD3_k127_3832075_3 NMT1-like family - - - 0.000000000000000000000000001182 126.0
HFD3_k127_3832075_4 Major facilitator Superfamily - - - 0.000000000000000000000000005969 124.0
HFD3_k127_3832075_5 Belongs to the major facilitator superfamily - - - 0.0006973 45.0
HFD3_k127_3849044_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 438.0
HFD3_k127_3849044_1 Ethanolamine utilisation protein EutA K04019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 321.0
HFD3_k127_3849044_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
HFD3_k127_3887196_0 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000002867 183.0
HFD3_k127_3887196_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000007539 124.0
HFD3_k127_3887196_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000001506 82.0
HFD3_k127_3887196_3 SET domain K07117 - - 0.0002627 51.0
HFD3_k127_389013_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 417.0
HFD3_k127_389013_1 with the TIM-barrel fold - - - 0.00000000000000000000000000000001096 140.0
HFD3_k127_389013_2 - - - - 0.00000000000000000000000000000001949 128.0
HFD3_k127_3917708_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 486.0
HFD3_k127_3917708_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 456.0
HFD3_k127_3917708_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000004043 143.0
HFD3_k127_3917708_11 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000004457 132.0
HFD3_k127_3917708_12 VanZ like family - - - 0.00000000000000000000008069 105.0
HFD3_k127_3917708_13 ABC transporter substrate-binding protein K02051 - - 0.0000007557 60.0
HFD3_k127_3917708_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 395.0
HFD3_k127_3917708_3 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 386.0
HFD3_k127_3917708_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 338.0
HFD3_k127_3917708_5 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006104 267.0
HFD3_k127_3917708_6 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000007146 256.0
HFD3_k127_3917708_7 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000000004494 169.0
HFD3_k127_3917708_8 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000001433 173.0
HFD3_k127_3917708_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000003628 177.0
HFD3_k127_3923276_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001957 273.0
HFD3_k127_3923276_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000003206 191.0
HFD3_k127_3923276_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000004288 96.0
HFD3_k127_3923276_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000175 94.0
HFD3_k127_3923276_4 glyoxalase bleomycin resistance protein dioxygenase K01759,K08234 - 4.4.1.5 0.00000000000000000002555 95.0
HFD3_k127_3923276_5 ABC transporter K02051,K15553 - - 0.000000000006722 76.0
HFD3_k127_3923276_6 membrane transporter protein K07090 - - 0.0000000002171 64.0
HFD3_k127_3923276_7 Belongs to the ompA family - - - 0.0002323 49.0
HFD3_k127_3923331_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 409.0
HFD3_k127_3923331_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 392.0
HFD3_k127_3923331_2 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 286.0
HFD3_k127_3923331_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000009255 220.0
HFD3_k127_3923331_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
HFD3_k127_3923331_5 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000006363 137.0
HFD3_k127_3923331_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0000000000007345 79.0
HFD3_k127_3923331_7 Pfam:DUF3596 K14059 - - 0.00000001201 57.0
HFD3_k127_3923331_8 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000001996 57.0
HFD3_k127_3927013_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 535.0
HFD3_k127_3927013_1 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 334.0
HFD3_k127_3927013_2 Glyoxalase-like domain - - - 0.0000000000000000000000000007722 120.0
HFD3_k127_3927013_3 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000007857 108.0
HFD3_k127_3927013_4 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.000000000009902 69.0
HFD3_k127_3927013_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000007463 73.0
HFD3_k127_3929170_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 434.0
HFD3_k127_3929170_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005142 272.0
HFD3_k127_3929170_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.0000000000000000000000000000000000000000000000000000008117 199.0
HFD3_k127_394115_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 448.0
HFD3_k127_394115_1 NMT1-like family - - - 0.00000000008139 73.0
HFD3_k127_3944557_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.696e-198 629.0
HFD3_k127_3944557_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 608.0
HFD3_k127_3944557_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001832 284.0
HFD3_k127_3944557_11 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003169 281.0
HFD3_k127_3944557_12 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 280.0
HFD3_k127_3944557_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003609 253.0
HFD3_k127_3944557_14 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000003838 186.0
HFD3_k127_3944557_15 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000002081 180.0
HFD3_k127_3944557_16 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000004334 171.0
HFD3_k127_3944557_17 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000005898 101.0
HFD3_k127_3944557_18 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000003263 85.0
HFD3_k127_3944557_19 DNA-templated transcription, initiation K03088 - - 0.00000002807 57.0
HFD3_k127_3944557_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 530.0
HFD3_k127_3944557_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 383.0
HFD3_k127_3944557_4 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 351.0
HFD3_k127_3944557_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 344.0
HFD3_k127_3944557_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 321.0
HFD3_k127_3944557_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 320.0
HFD3_k127_3944557_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 294.0
HFD3_k127_3944557_9 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000203 295.0
HFD3_k127_3950919_0 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
HFD3_k127_3950919_1 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000007895 247.0
HFD3_k127_3950919_2 - - - - 0.00000000000000000000000000000000000000000000000000001003 198.0
HFD3_k127_3950919_3 - - - - 0.00000000000000000000000000000000000000000000000005305 184.0
HFD3_k127_3950919_4 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000000000000002684 136.0
HFD3_k127_3950919_5 - - - - 0.00000000000000003365 87.0
HFD3_k127_39588_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 323.0
HFD3_k127_39588_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000003738 180.0
HFD3_k127_39588_2 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.00000001091 66.0
HFD3_k127_396016_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 472.0
HFD3_k127_396016_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 432.0
HFD3_k127_396016_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897,K12507 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 308.0
HFD3_k127_396016_3 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000008233 132.0
HFD3_k127_396016_4 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000005311 84.0
HFD3_k127_396016_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000005943 69.0
HFD3_k127_396016_6 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.00000003641 59.0
HFD3_k127_396016_7 Transcriptional regulator - - - 0.0000621 48.0
HFD3_k127_396016_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000876 51.0
HFD3_k127_3966616_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.265e-283 888.0
HFD3_k127_3966616_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002422 244.0
HFD3_k127_3966616_2 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000009934 169.0
HFD3_k127_3966616_3 Iron Permease K07243 - - 0.00000000000000000000003621 103.0
HFD3_k127_3966616_4 lactate metabolic process K00113 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.00000000000136 70.0
HFD3_k127_3966616_5 FeoC like transcriptional regulator - - - 0.0005687 47.0
HFD3_k127_3969753_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1619.0
HFD3_k127_3969753_1 Multidrug ABC transporter ATP-binding protein K01990 - - 7.618e-241 758.0
HFD3_k127_3969753_10 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000333 244.0
HFD3_k127_3969753_11 transcriptional regulator K09017 - - 0.0000000000000002914 80.0
HFD3_k127_3969753_12 Protein of unknown function (DUF502) - - - 0.0000000000000003113 83.0
HFD3_k127_3969753_13 Thioredoxin M-type K03671 - - 0.000000001412 61.0
HFD3_k127_3969753_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 501.0
HFD3_k127_3969753_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
HFD3_k127_3969753_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 486.0
HFD3_k127_3969753_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 458.0
HFD3_k127_3969753_6 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 387.0
HFD3_k127_3969753_7 3-methyl-2-oxobutanoate hydroxymethyltransferase activity K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 334.0
HFD3_k127_3969753_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
HFD3_k127_3969753_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004481 246.0
HFD3_k127_3970835_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 2.43e-288 893.0
HFD3_k127_3970835_1 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000002203 181.0
HFD3_k127_3970835_2 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000003843 129.0
HFD3_k127_3970835_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000002205 121.0
HFD3_k127_3970835_4 glutamine synthetase K01915 - 6.3.1.2 0.000000000000001448 76.0
HFD3_k127_3984704_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 404.0
HFD3_k127_3984704_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 380.0
HFD3_k127_3994785_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 471.0
HFD3_k127_3994785_1 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 467.0
HFD3_k127_3994785_10 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000008854 185.0
HFD3_k127_3994785_11 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000008803 184.0
HFD3_k127_3994785_12 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000001847 135.0
HFD3_k127_3994785_13 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000002876 130.0
HFD3_k127_3994785_14 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000008431 124.0
HFD3_k127_3994785_15 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000005382 120.0
HFD3_k127_3994785_16 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000004839 115.0
HFD3_k127_3994785_17 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000001775 95.0
HFD3_k127_3994785_18 Lipocalin-like domain - - - 0.0000000000007408 75.0
HFD3_k127_3994785_19 NMT1-like family K02051 - - 0.000000000002537 78.0
HFD3_k127_3994785_2 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 426.0
HFD3_k127_3994785_20 NMT1-like family - - - 0.0000000000318 75.0
HFD3_k127_3994785_21 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000007538 73.0
HFD3_k127_3994785_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 407.0
HFD3_k127_3994785_4 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 336.0
HFD3_k127_3994785_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 313.0
HFD3_k127_3994785_6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000001162 275.0
HFD3_k127_3994785_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001308 270.0
HFD3_k127_3994785_8 ABC-type Fe3 transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
HFD3_k127_3994785_9 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000004511 252.0
HFD3_k127_4003564_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 375.0
HFD3_k127_4003564_1 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 330.0
HFD3_k127_4003564_2 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001597 261.0
HFD3_k127_4003564_3 - - - - 0.00000000000000000000000000000000008588 139.0
HFD3_k127_4003564_4 Major facilitator superfamily - - - 0.000000000000000000000000000000001648 139.0
HFD3_k127_4003564_5 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000001325 130.0
HFD3_k127_4003564_6 Universal stress protein family - - - 0.0000000000000000002618 93.0
HFD3_k127_4003564_7 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000003453 64.0
HFD3_k127_4003564_8 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000004541 63.0
HFD3_k127_4005981_0 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000014 141.0
HFD3_k127_4005981_2 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000003836 86.0
HFD3_k127_4005981_3 Peptidase M50 K16922 - - 0.00000000000008147 82.0
HFD3_k127_4022755_0 Required for chromosome condensation and partitioning K03529 - - 1.848e-225 741.0
HFD3_k127_4022755_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 549.0
HFD3_k127_4022755_10 nucleotidyltransferase activity K07061,K07075 - - 0.00001542 50.0
HFD3_k127_4022755_2 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 344.0
HFD3_k127_4022755_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 340.0
HFD3_k127_4022755_4 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 271.0
HFD3_k127_4022755_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000001778 150.0
HFD3_k127_4022755_6 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000000000000009152 136.0
HFD3_k127_4022755_7 helicase activity - - - 0.0000000000000000000000000002395 118.0
HFD3_k127_4022755_8 ORF6N domain - - - 0.00000000001711 66.0
HFD3_k127_4022755_9 Protein of unknown function DUF86 - - - 0.00001336 48.0
HFD3_k127_4029691_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 566.0
HFD3_k127_4029691_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000209 190.0
HFD3_k127_4029691_2 PAS fold - - - 0.000000000000000000000000000000000000001093 164.0
HFD3_k127_4029691_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000004944 52.0
HFD3_k127_4035181_0 Uncharacterised protein family (UPF0182) K09118 - - 8.457e-277 878.0
HFD3_k127_4035181_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 505.0
HFD3_k127_4035181_10 with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000003057 172.0
HFD3_k127_4035181_11 FCD K05799 - - 0.000000000000000000000000000000000000003601 155.0
HFD3_k127_4035181_12 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000006999 162.0
HFD3_k127_4035181_13 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000245 107.0
HFD3_k127_4035181_14 lactoylglutathione lyase activity K11210 - - 0.000000000385 70.0
HFD3_k127_4035181_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000008492 63.0
HFD3_k127_4035181_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
HFD3_k127_4035181_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
HFD3_k127_4035181_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
HFD3_k127_4035181_5 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 348.0
HFD3_k127_4035181_6 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 319.0
HFD3_k127_4035181_7 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 309.0
HFD3_k127_4035181_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000004471 207.0
HFD3_k127_4035181_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000004063 192.0
HFD3_k127_4076913_0 Helix-hairpin-helix containing domain K03581 - 3.1.11.5 2.534e-214 688.0
HFD3_k127_4076913_1 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 427.0
HFD3_k127_4076913_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 376.0
HFD3_k127_4076913_3 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 363.0
HFD3_k127_4076913_4 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 341.0
HFD3_k127_4076913_5 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000006594 158.0
HFD3_k127_4076913_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000008208 137.0
HFD3_k127_40878_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.994e-206 648.0
HFD3_k127_40878_1 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 348.0
HFD3_k127_40878_2 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004396 267.0
HFD3_k127_40878_3 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000002402 212.0
HFD3_k127_40878_4 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000001003 215.0
HFD3_k127_40878_5 Histidine phosphatase superfamily (branch 1) K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000135 132.0
HFD3_k127_4088024_0 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 433.0
HFD3_k127_4088024_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 396.0
HFD3_k127_4088024_10 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001407 162.0
HFD3_k127_4088024_11 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000004979 158.0
HFD3_k127_4088024_12 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000002372 151.0
HFD3_k127_4088024_13 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000001047 115.0
HFD3_k127_4088024_14 DoxX K03885,K16937 - 1.6.99.3,1.8.5.2 0.00000000000000000000001233 110.0
HFD3_k127_4088024_15 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000002617 104.0
HFD3_k127_4088024_16 acetoin utilization protein K04767 - - 0.000000000000000000001964 100.0
HFD3_k127_4088024_17 Glutaredoxin - - - 0.00000000000003974 73.0
HFD3_k127_4088024_18 NMT1-like family - - - 0.0000000000001407 81.0
HFD3_k127_4088024_19 apoptosis-inducing factor - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005783,GO:0006915,GO:0008150,GO:0008219,GO:0009987,GO:0012501,GO:0012505,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0097194 - 0.000000000005467 70.0
HFD3_k127_4088024_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
HFD3_k127_4088024_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 333.0
HFD3_k127_4088024_4 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004144 252.0
HFD3_k127_4088024_5 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000005916 232.0
HFD3_k127_4088024_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000194 211.0
HFD3_k127_4088024_7 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
HFD3_k127_4088024_8 GTP binding K09767 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000423 194.0
HFD3_k127_4088024_9 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000759 165.0
HFD3_k127_4121151_0 2-epimerase K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 377.0
HFD3_k127_4121151_1 Catalyzes the NAD-dependent oxidation of glucose 6- phosphate to 6-phosphogluconolactone K19243 - 1.1.1.388 0.000000000000000000000000000000008194 137.0
HFD3_k127_4121151_2 Catalyzes the NAD-dependent oxidation of glucose 6- phosphate to 6-phosphogluconolactone K19243 - 1.1.1.388 0.0000000000000000000000000000008538 130.0
HFD3_k127_4121151_3 Glycosyltransferase like family 2 - - - 0.000000000002196 67.0
HFD3_k127_4121151_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000001969 72.0
HFD3_k127_4121151_5 Uncharacterised nucleotidyltransferase - - - 0.00000002403 64.0
HFD3_k127_4121151_6 GPI mannosyltransferase 1 (S. cerevisiae)-like protein - - - 0.00001611 57.0
HFD3_k127_4134752_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000000003973 192.0
HFD3_k127_4134752_1 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000258 158.0
HFD3_k127_4152761_0 4Fe-4S dicluster domain K00184 - - 0.0 1213.0
HFD3_k127_4152761_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 7.512e-281 872.0
HFD3_k127_4152761_10 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
HFD3_k127_4152761_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
HFD3_k127_4152761_12 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000009984 97.0
HFD3_k127_4152761_13 - - - - 0.0000000000000005695 84.0
HFD3_k127_4152761_2 Polysulphide reductase, NrfD K00185 - - 3.932e-221 692.0
HFD3_k127_4152761_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 425.0
HFD3_k127_4152761_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 409.0
HFD3_k127_4152761_5 protein involved in outer membrane biogenesis K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 420.0
HFD3_k127_4152761_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 340.0
HFD3_k127_4152761_7 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 302.0
HFD3_k127_4152761_8 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 304.0
HFD3_k127_4152761_9 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000242 265.0
HFD3_k127_4222981_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1116.0
HFD3_k127_4222981_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.636e-314 974.0
HFD3_k127_4222981_2 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 381.0
HFD3_k127_4222981_3 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 333.0
HFD3_k127_4222981_4 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000112 214.0
HFD3_k127_4222981_5 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000001758 180.0
HFD3_k127_4222981_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000769 172.0
HFD3_k127_4222981_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000001314 116.0
HFD3_k127_4225211_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 555.0
HFD3_k127_4225211_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 458.0
HFD3_k127_4225211_10 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000006598 164.0
HFD3_k127_4225211_11 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000001659 160.0
HFD3_k127_4225211_12 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000002542 153.0
HFD3_k127_4225211_13 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000233 124.0
HFD3_k127_4225211_14 photosynthesis - - - 0.000000000000000000001329 104.0
HFD3_k127_4225211_15 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000001205 97.0
HFD3_k127_4225211_16 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000001083 89.0
HFD3_k127_4225211_17 CoA-transferase family III - - - 0.00001629 48.0
HFD3_k127_4225211_18 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00005674 51.0
HFD3_k127_4225211_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 367.0
HFD3_k127_4225211_3 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 331.0
HFD3_k127_4225211_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 295.0
HFD3_k127_4225211_5 Belongs to the enoyl-CoA hydratase isomerase family K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000004248 235.0
HFD3_k127_4225211_6 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000003296 224.0
HFD3_k127_4225211_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000008099 212.0
HFD3_k127_4225211_8 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000003006 208.0
HFD3_k127_4225211_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000002443 166.0
HFD3_k127_4228227_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 6.67e-316 990.0
HFD3_k127_4228227_1 PFAM Cytochrome b b6 domain - - - 4.383e-196 626.0
HFD3_k127_4228227_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 332.0
HFD3_k127_4228227_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 308.0
HFD3_k127_4228227_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000001552 120.0
HFD3_k127_4236364_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.184e-236 743.0
HFD3_k127_4236364_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000001403 210.0
HFD3_k127_4236364_2 tungstate binding K02020 - - 0.00000000000000000000000000000000000000000001255 171.0
HFD3_k127_4236364_3 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000001067 130.0
HFD3_k127_4236364_4 Histidine kinase-like ATPases - - - 0.00003804 53.0
HFD3_k127_4236364_5 Methyltransferase small domain - - - 0.00007829 52.0
HFD3_k127_4239106_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 341.0
HFD3_k127_4239106_1 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000000000000000003663 128.0
HFD3_k127_4239106_2 Histidine kinase K07681,K11617 - 2.7.13.3 0.00000000000000000000000009036 115.0
HFD3_k127_4239106_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001426 108.0
HFD3_k127_4239106_4 response regulator receiver - - - 0.000000000000000004278 96.0
HFD3_k127_4239367_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 435.0
HFD3_k127_4239367_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 342.0
HFD3_k127_4239367_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
HFD3_k127_4239367_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000043 257.0
HFD3_k127_4239367_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000166 209.0
HFD3_k127_4239367_5 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.000000000005994 69.0
HFD3_k127_4239367_6 gag-polyprotein putative aspartyl protease - - - 0.000002271 54.0
HFD3_k127_4272504_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 494.0
HFD3_k127_4272504_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 296.0
HFD3_k127_4272504_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 288.0
HFD3_k127_4331507_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007052 269.0
HFD3_k127_4331507_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000002274 187.0
HFD3_k127_4331507_2 - - - - 0.0000000000000000000000000000000000000000000000001102 182.0
HFD3_k127_4331507_3 FAD binding domain - - - 0.00000000000000000000000004338 117.0
HFD3_k127_4331507_5 NMT1-like family K02051 - - 0.000000004477 68.0
HFD3_k127_4331507_6 TIGRFAM aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein K02051 - - 0.00005813 55.0
HFD3_k127_4408_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 0.0 1118.0
HFD3_k127_4408_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 2.536e-300 950.0
HFD3_k127_4408_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 377.0
HFD3_k127_4408_11 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 372.0
HFD3_k127_4408_12 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 374.0
HFD3_k127_4408_13 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 370.0
HFD3_k127_4408_14 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 364.0
HFD3_k127_4408_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 334.0
HFD3_k127_4408_16 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 331.0
HFD3_k127_4408_17 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 323.0
HFD3_k127_4408_18 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 319.0
HFD3_k127_4408_19 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
HFD3_k127_4408_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.311e-232 743.0
HFD3_k127_4408_20 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000743 279.0
HFD3_k127_4408_21 YceG-like family K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 280.0
HFD3_k127_4408_22 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002879 272.0
HFD3_k127_4408_23 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001715 259.0
HFD3_k127_4408_24 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
HFD3_k127_4408_25 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
HFD3_k127_4408_26 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000005569 234.0
HFD3_k127_4408_27 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000004221 218.0
HFD3_k127_4408_28 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000006169 204.0
HFD3_k127_4408_29 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003752 203.0
HFD3_k127_4408_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.488e-219 695.0
HFD3_k127_4408_30 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000004824 208.0
HFD3_k127_4408_31 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006588 184.0
HFD3_k127_4408_32 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000001452 189.0
HFD3_k127_4408_33 cytochrome c - - - 0.00000000000000000000000000000000000000000000000007232 190.0
HFD3_k127_4408_34 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000008576 191.0
HFD3_k127_4408_35 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000005212 169.0
HFD3_k127_4408_36 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000006482 161.0
HFD3_k127_4408_37 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000007103 154.0
HFD3_k127_4408_38 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000004447 149.0
HFD3_k127_4408_39 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001635 138.0
HFD3_k127_4408_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 507.0
HFD3_k127_4408_40 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000001239 127.0
HFD3_k127_4408_41 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000002143 117.0
HFD3_k127_4408_42 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000001397 122.0
HFD3_k127_4408_43 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000001864 109.0
HFD3_k127_4408_44 - - - - 0.00000000000000000000005791 99.0
HFD3_k127_4408_45 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000001076 103.0
HFD3_k127_4408_46 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000005099 110.0
HFD3_k127_4408_47 repeat protein - - - 0.000000000000000000007804 105.0
HFD3_k127_4408_48 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000001299 99.0
HFD3_k127_4408_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 490.0
HFD3_k127_4408_50 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000002312 100.0
HFD3_k127_4408_51 - - - - 0.000000000000000004738 91.0
HFD3_k127_4408_52 repeat protein - - - 0.0000000000001516 83.0
HFD3_k127_4408_53 GHKL domain - - - 0.00000000044 72.0
HFD3_k127_4408_54 Putative regulatory protein - - - 0.000000005514 59.0
HFD3_k127_4408_56 von Willebrand factor, type A - - - 0.000005356 59.0
HFD3_k127_4408_57 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00001737 56.0
HFD3_k127_4408_58 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0004922 51.0
HFD3_k127_4408_6 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 482.0
HFD3_k127_4408_7 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 460.0
HFD3_k127_4408_8 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 401.0
HFD3_k127_4408_9 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
HFD3_k127_4430659_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 2.085e-304 948.0
HFD3_k127_4430659_1 Tripartite tricarboxylate transporter TctA family K07793 - - 9.958e-235 734.0
HFD3_k127_4430659_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.064e-195 621.0
HFD3_k127_4430659_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 476.0
HFD3_k127_4430659_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004627 261.0
HFD3_k127_4430659_5 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000919 174.0
HFD3_k127_4430659_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000005354 182.0
HFD3_k127_4430659_7 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000005198 66.0
HFD3_k127_4430659_8 Tripartite tricarboxylate transporter family receptor - - - 0.000002343 51.0
HFD3_k127_4446001_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.505e-231 732.0
HFD3_k127_4446001_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.426e-199 626.0
HFD3_k127_4446001_10 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000003819 195.0
HFD3_k127_4446001_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001663 203.0
HFD3_k127_4446001_12 NIPSNAP - - - 0.0000000000000000000000000000000000000000000001286 177.0
HFD3_k127_4446001_13 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000004302 174.0
HFD3_k127_4446001_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000628 162.0
HFD3_k127_4446001_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000005255 136.0
HFD3_k127_4446001_16 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000009395 134.0
HFD3_k127_4446001_17 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000001056 136.0
HFD3_k127_4446001_18 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000007641 127.0
HFD3_k127_4446001_19 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000818 122.0
HFD3_k127_4446001_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 432.0
HFD3_k127_4446001_20 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000004748 119.0
HFD3_k127_4446001_21 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000001041 120.0
HFD3_k127_4446001_22 Belongs to the ompA family K03286 - - 0.00000000000000003468 94.0
HFD3_k127_4446001_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000005324 83.0
HFD3_k127_4446001_24 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000001082 83.0
HFD3_k127_4446001_25 major facilitator superfamily MFS_1 - - - 0.00000000002756 68.0
HFD3_k127_4446001_26 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000004076 57.0
HFD3_k127_4446001_28 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00001962 50.0
HFD3_k127_4446001_29 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00002564 52.0
HFD3_k127_4446001_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 366.0
HFD3_k127_4446001_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 347.0
HFD3_k127_4446001_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 347.0
HFD3_k127_4446001_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000022 291.0
HFD3_k127_4446001_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001516 237.0
HFD3_k127_4446001_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000005836 216.0
HFD3_k127_4446001_9 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.0000000000000000000000000000000000000000000000000000004022 202.0
HFD3_k127_4467351_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 564.0
HFD3_k127_4467351_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 384.0
HFD3_k127_4467351_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000006168 241.0
HFD3_k127_4467351_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000003729 188.0
HFD3_k127_4467351_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000002564 156.0
HFD3_k127_4467351_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.00000007205 63.0
HFD3_k127_4467351_6 PFAM Integrase catalytic region K07497 - - 0.0000957 46.0
HFD3_k127_4520213_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.451e-197 630.0
HFD3_k127_4520213_1 ligase activity K18661,K22133 - 6.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 501.0
HFD3_k127_4520213_10 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000008281 178.0
HFD3_k127_4520213_11 - Amino acid transport and metabolism K01953 - 6.3.5.4 0.0000000000000000000000000000000000003736 160.0
HFD3_k127_4520213_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000002037 86.0
HFD3_k127_4520213_13 - - - - 0.000000000004719 77.0
HFD3_k127_4520213_14 TPR repeat - - - 0.00000003593 63.0
HFD3_k127_4520213_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 443.0
HFD3_k127_4520213_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 437.0
HFD3_k127_4520213_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 359.0
HFD3_k127_4520213_5 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 331.0
HFD3_k127_4520213_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
HFD3_k127_4520213_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 297.0
HFD3_k127_4520213_8 Glycosyl transferases group 1 K21001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000243 280.0
HFD3_k127_4520213_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000011 179.0
HFD3_k127_4526137_0 transport system fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 503.0
HFD3_k127_4526137_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 346.0
HFD3_k127_4526137_10 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.00000000000000000003638 92.0
HFD3_k127_4526137_12 PFAM D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0001259 47.0
HFD3_k127_4526137_13 TRAP transporter solute receptor TAXI family protein K07080 - - 0.0001415 48.0
HFD3_k127_4526137_2 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 291.0
HFD3_k127_4526137_3 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007123 265.0
HFD3_k127_4526137_4 PFAM Glycine sarcosine betaine reductase component B subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000009255 250.0
HFD3_k127_4526137_6 TRAP transporter solute receptor TAXI family protein K07080 - - 0.00000000000000000000000000000000000005186 152.0
HFD3_k127_4526137_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000042 132.0
HFD3_k127_4526137_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000003473 93.0
HFD3_k127_4550119_0 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 497.0
HFD3_k127_4550119_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
HFD3_k127_4550119_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
HFD3_k127_4550119_3 Glutathione S-transferase, N-terminal domain - - - 0.0000000000006818 69.0
HFD3_k127_458271_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.015e-255 797.0
HFD3_k127_458271_1 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 387.0
HFD3_k127_458271_2 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 326.0
HFD3_k127_458271_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
HFD3_k127_458271_4 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HFD3_k127_458271_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000006182 144.0
HFD3_k127_458271_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000547 138.0
HFD3_k127_458271_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000007831 91.0
HFD3_k127_4604652_0 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 550.0
HFD3_k127_4604652_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13308,K20429 GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771 2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 500.0
HFD3_k127_4604652_2 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
HFD3_k127_4604652_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005727 252.0
HFD3_k127_4604652_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000009217 229.0
HFD3_k127_4604652_5 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000002034 138.0
HFD3_k127_4604652_6 Sulfotransferase family - - - 0.00000000009315 66.0
HFD3_k127_4660067_0 PD-(D/E)XK nuclease superfamily - - - 7.797e-245 796.0
HFD3_k127_4660067_2 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 577.0
HFD3_k127_4660067_3 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000005131 234.0
HFD3_k127_4660067_4 Domain of unknown function (DUF4145) - - - 0.0000000000000000000000000000000000004387 148.0
HFD3_k127_4660067_5 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.00000000000000000000000000002184 125.0
HFD3_k127_4660067_6 Plasmid stabilization system - - - 0.000000000000000000007799 95.0
HFD3_k127_4666637_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 364.0
HFD3_k127_4666637_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000002855 224.0
HFD3_k127_4666637_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000002053 184.0
HFD3_k127_4666637_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000001254 113.0
HFD3_k127_4666637_4 Protein conserved in bacteria - - - 0.00001795 48.0
HFD3_k127_4673901_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1726.0
HFD3_k127_4673901_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 596.0
HFD3_k127_4673901_10 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000007293 196.0
HFD3_k127_4673901_11 Membrane K08988 - - 0.000000000000000000000000000000000000000000003716 174.0
HFD3_k127_4673901_12 arsR family - - - 0.0000000000000000000000000000000000000000001405 176.0
HFD3_k127_4673901_13 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000008028 154.0
HFD3_k127_4673901_14 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000005352 149.0
HFD3_k127_4673901_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002944 138.0
HFD3_k127_4673901_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000007439 138.0
HFD3_k127_4673901_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000004064 122.0
HFD3_k127_4673901_18 NMT1-like family K07080 - - 0.0000000000000000000000000008772 124.0
HFD3_k127_4673901_19 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000001207 88.0
HFD3_k127_4673901_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 524.0
HFD3_k127_4673901_20 Tripartite tricarboxylate transporter family receptor - - - 0.00000000008326 66.0
HFD3_k127_4673901_21 - - - - 0.000001182 55.0
HFD3_k127_4673901_22 Transposase IS200 like - - - 0.00003487 47.0
HFD3_k127_4673901_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 392.0
HFD3_k127_4673901_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HFD3_k127_4673901_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 306.0
HFD3_k127_4673901_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004001 265.0
HFD3_k127_4673901_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000003523 234.0
HFD3_k127_4673901_8 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000001228 213.0
HFD3_k127_4673901_9 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
HFD3_k127_4676246_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 581.0
HFD3_k127_4676246_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 573.0
HFD3_k127_4676246_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 442.0
HFD3_k127_4676246_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000007019 216.0
HFD3_k127_4676246_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000002499 213.0
HFD3_k127_4676246_5 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000156 166.0
HFD3_k127_4676246_6 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000165 134.0
HFD3_k127_4676246_7 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000004556 111.0
HFD3_k127_4676246_8 ornithine cyclodeaminase mu-crystallin K19244 - 1.4.1.1 0.00000000000000006251 89.0
HFD3_k127_4689626_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 577.0
HFD3_k127_4689626_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 329.0
HFD3_k127_4689626_2 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000002347 248.0
HFD3_k127_4689626_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000001638 179.0
HFD3_k127_4689626_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000004947 141.0
HFD3_k127_4691978_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.387e-267 847.0
HFD3_k127_4691978_1 geranylgeranyl reductase activity - - - 6.074e-225 705.0
HFD3_k127_4691978_2 Elements of external origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 567.0
HFD3_k127_4691978_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 558.0
HFD3_k127_4691978_4 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 406.0
HFD3_k127_4691978_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 289.0
HFD3_k127_4691978_6 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 269.0
HFD3_k127_4691978_7 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000002991 154.0
HFD3_k127_4691978_8 - - - - 0.00000000000000009124 82.0
HFD3_k127_4723848_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
HFD3_k127_4723848_1 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 354.0
HFD3_k127_4723848_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004911 270.0
HFD3_k127_4723848_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 267.0
HFD3_k127_4723848_4 CoA-transferase family III K07543 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000003893 223.0
HFD3_k127_4723848_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000005333 170.0
HFD3_k127_4723848_6 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000000000002047 154.0
HFD3_k127_4723848_7 NMT1-like family - - - 0.00000000000000000000000000000003666 138.0
HFD3_k127_4723848_8 - - - - 0.0000000004525 63.0
HFD3_k127_4737311_0 PFAM CheR methyltransferase, SAM binding domain K00575,K13924 - 2.1.1.80,3.1.1.61 1.391e-238 754.0
HFD3_k127_4737311_1 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 297.0
HFD3_k127_4737311_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000005157 246.0
HFD3_k127_4737311_3 AsmA-like C-terminal region - - - 0.0000000000000008661 91.0
HFD3_k127_4740367_0 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 360.0
HFD3_k127_4740367_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 330.0
HFD3_k127_4740367_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 311.0
HFD3_k127_4740367_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 317.0
HFD3_k127_4740367_4 Endoribonuclease L-PSP - - - 0.000000000000000000000001469 108.0
HFD3_k127_4740367_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000004571 96.0
HFD3_k127_4743224_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 6.184e-245 781.0
HFD3_k127_4743224_1 Cell division protein 48, CDC48, domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 602.0
HFD3_k127_4743224_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000001825 241.0
HFD3_k127_4743224_11 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000001095 225.0
HFD3_k127_4743224_12 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000452 218.0
HFD3_k127_4743224_13 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000002464 222.0
HFD3_k127_4743224_14 membrane K02050 - - 0.000000000000000000000000000000000000000000000000000000000005061 216.0
HFD3_k127_4743224_15 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002399 206.0
HFD3_k127_4743224_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000003038 198.0
HFD3_k127_4743224_17 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000003957 197.0
HFD3_k127_4743224_18 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000396 186.0
HFD3_k127_4743224_19 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000001999 180.0
HFD3_k127_4743224_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K16877 - 1.3.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 541.0
HFD3_k127_4743224_22 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000002787 108.0
HFD3_k127_4743224_23 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000512 79.0
HFD3_k127_4743224_24 NMT1-like family K02051 - - 0.000001414 60.0
HFD3_k127_4743224_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 516.0
HFD3_k127_4743224_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 439.0
HFD3_k127_4743224_5 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006187 285.0
HFD3_k127_4743224_6 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001363 277.0
HFD3_k127_4743224_7 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006173 264.0
HFD3_k127_4743224_8 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002407 262.0
HFD3_k127_4743224_9 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000009691 246.0
HFD3_k127_4744188_0 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 562.0
HFD3_k127_4744188_1 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 520.0
HFD3_k127_4744188_2 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 473.0
HFD3_k127_4744188_3 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 399.0
HFD3_k127_4744188_4 PFAM AMP-dependent synthetase ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001561 243.0
HFD3_k127_4744188_5 MbtH-like protein K05375 - - 0.000000000000000000000000000000000209 132.0
HFD3_k127_4744188_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00002448 56.0
HFD3_k127_4748013_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000006015 198.0
HFD3_k127_4748013_1 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000000000000001422 176.0
HFD3_k127_4748013_10 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00004089 48.0
HFD3_k127_4748013_11 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0005692 43.0
HFD3_k127_4748013_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000987 144.0
HFD3_k127_4748013_3 protein conserved in bacteria - - - 0.000000000000000000000000000000001717 139.0
HFD3_k127_4748013_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000004451 132.0
HFD3_k127_4748013_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000005956 97.0
HFD3_k127_4748013_6 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000004571 96.0
HFD3_k127_4748013_7 ACT domain - - - 0.00000000000002527 78.0
HFD3_k127_4748013_8 transferase activity, transferring glycosyl groups K00786 - - 0.000000004858 67.0
HFD3_k127_4748013_9 - - - - 0.000000294 55.0
HFD3_k127_4757127_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 7.671e-202 641.0
HFD3_k127_4757127_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897,K12507 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 371.0
HFD3_k127_4757127_2 DJ-1/PfpI family K18881 - 4.2.1.130 0.000000000000000000000000000000000000000000003309 179.0
HFD3_k127_4762548_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1555.0
HFD3_k127_4762548_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.1e-285 900.0
HFD3_k127_4762548_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000001757 223.0
HFD3_k127_4762548_11 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000001707 188.0
HFD3_k127_4762548_12 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000000001766 177.0
HFD3_k127_4762548_13 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000001883 152.0
HFD3_k127_4762548_14 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000009298 113.0
HFD3_k127_4762548_15 - - - - 0.00000000001988 70.0
HFD3_k127_4762548_16 Protein of unknown function (DUF1488) - - - 0.000003838 54.0
HFD3_k127_4762548_17 Sigma-70, region 4 K03087 - - 0.00001036 48.0
HFD3_k127_4762548_2 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 575.0
HFD3_k127_4762548_3 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 516.0
HFD3_k127_4762548_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 505.0
HFD3_k127_4762548_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 476.0
HFD3_k127_4762548_6 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 417.0
HFD3_k127_4762548_7 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 373.0
HFD3_k127_4762548_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 361.0
HFD3_k127_4762548_9 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 326.0
HFD3_k127_4764607_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.106e-287 902.0
HFD3_k127_4764607_1 NADH dehydrogenase (ubiquinone) activity K14089 - - 5.257e-248 774.0
HFD3_k127_4764607_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000001451 72.0
HFD3_k127_4764607_11 Pentapeptide repeats (8 copies) - - - 0.000000000832 68.0
HFD3_k127_4764607_2 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 4.971e-208 657.0
HFD3_k127_4764607_3 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 456.0
HFD3_k127_4764607_4 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 442.0
HFD3_k127_4764607_5 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 413.0
HFD3_k127_4764607_6 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 329.0
HFD3_k127_4764607_7 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001578 277.0
HFD3_k127_4764607_8 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 280.0
HFD3_k127_4764607_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000222 133.0
HFD3_k127_476671_0 Alpha-amylase domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1427.0
HFD3_k127_476671_1 Maltooligosyl trehalose synthase K06044 - 5.4.99.15 0.0 1086.0
HFD3_k127_476671_10 YtxH-like protein - - - 0.000009884 51.0
HFD3_k127_476671_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.506e-274 860.0
HFD3_k127_476671_3 Sigma-54 interaction domain K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 599.0
HFD3_k127_476671_4 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 323.0
HFD3_k127_476671_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
HFD3_k127_476671_6 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000001608 217.0
HFD3_k127_476671_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000003608 121.0
HFD3_k127_476671_8 - - - - 0.000000000000000000948 88.0
HFD3_k127_476671_9 SMART Transport-associated and nodulation region K04065 - - 0.00000007383 58.0
HFD3_k127_4769856_0 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 414.0
HFD3_k127_4769856_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 378.0
HFD3_k127_4769856_2 NMT1-like family K02051 - - 0.0000000000004006 80.0
HFD3_k127_4769856_3 - - - - 0.0000008634 59.0
HFD3_k127_4771142_0 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000005718 192.0
HFD3_k127_4771142_1 Transposase, Mutator family K07493 - - 0.0000000000000000000000000000000588 124.0
HFD3_k127_4771142_2 Ribbon-helix-helix domain - - - 0.000000000007794 71.0
HFD3_k127_4780768_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.813e-228 728.0
HFD3_k127_4780768_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 552.0
HFD3_k127_4780768_10 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000003685 178.0
HFD3_k127_4780768_11 - - - - 0.00000000000000000000000000000000175 138.0
HFD3_k127_4780768_12 - - - - 0.000000000000000000000000000002808 129.0
HFD3_k127_4780768_13 - - - - 0.00000000000000001865 91.0
HFD3_k127_4780768_15 - - - - 0.000000618 51.0
HFD3_k127_4780768_16 tetratricopeptide repeat - - - 0.0005731 50.0
HFD3_k127_4780768_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 470.0
HFD3_k127_4780768_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 454.0
HFD3_k127_4780768_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 361.0
HFD3_k127_4780768_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 308.0
HFD3_k127_4780768_6 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000109 274.0
HFD3_k127_4780768_7 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000002864 233.0
HFD3_k127_4780768_8 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
HFD3_k127_4780768_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000003543 169.0
HFD3_k127_4781888_0 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001668 247.0
HFD3_k127_4781888_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000005044 200.0
HFD3_k127_4781888_2 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000006797 166.0
HFD3_k127_4784449_0 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002321 148.0
HFD3_k127_4784449_1 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000001034 118.0
HFD3_k127_4784449_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003755 104.0
HFD3_k127_4784449_3 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000001191 98.0
HFD3_k127_4784449_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000002306 89.0
HFD3_k127_4819359_0 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 554.0
HFD3_k127_4819359_1 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 418.0
HFD3_k127_4819359_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 342.0
HFD3_k127_4819359_3 Cupin domain K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 318.0
HFD3_k127_4819359_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 305.0
HFD3_k127_4819359_5 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000002401 231.0
HFD3_k127_4819359_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000002506 125.0
HFD3_k127_4819359_7 PBS lyase HEAT-like repeat - - - 0.000000000000000000004361 108.0
HFD3_k127_4819359_8 Putative zinc-finger - - - 0.000004995 55.0
HFD3_k127_4819359_9 Putative zinc-finger - - - 0.00005114 50.0
HFD3_k127_4821163_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 397.0
HFD3_k127_4821163_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000007006 176.0
HFD3_k127_4821163_2 Lycopene cyclase protein - - - 0.00000000000000117 89.0
HFD3_k127_4843958_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 351.0
HFD3_k127_4843958_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 329.0
HFD3_k127_4843958_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000004497 218.0
HFD3_k127_4843958_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000007536 191.0
HFD3_k127_4843958_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000001759 107.0
HFD3_k127_4853108_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 497.0
HFD3_k127_4853108_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 311.0
HFD3_k127_4853108_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 267.0
HFD3_k127_4853108_3 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000003765 168.0
HFD3_k127_4853108_4 - - - - 0.000000000000000000006975 100.0
HFD3_k127_4853656_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 631.0
HFD3_k127_4853656_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 411.0
HFD3_k127_4853656_2 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.00002545 50.0
HFD3_k127_4863645_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 420.0
HFD3_k127_4863645_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 413.0
HFD3_k127_4863645_2 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000489 274.0
HFD3_k127_4863645_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000008177 209.0
HFD3_k127_4863645_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000008286 191.0
HFD3_k127_4863645_5 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000007431 160.0
HFD3_k127_4863645_6 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000002413 138.0
HFD3_k127_4863645_7 Luciferase-like monooxygenase - - - 0.000000000000000000000004545 109.0
HFD3_k127_4863645_8 NMT1-like family K02051 - - 0.0000004369 60.0
HFD3_k127_486521_0 NADH oxidase K00219 - 1.3.1.34 2.85e-247 779.0
HFD3_k127_486521_1 amidohydrolase K03392,K07045 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 437.0
HFD3_k127_4916706_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1433.0
HFD3_k127_4916706_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1347.0
HFD3_k127_4916706_10 Cytochrome c - - - 0.00000000000000000001788 96.0
HFD3_k127_4916706_11 PFAM CBS domain K04767 - - 0.00000000000000000002764 97.0
HFD3_k127_4916706_12 - - - - 0.000000000004606 71.0
HFD3_k127_4916706_13 Cation transporting ATPase, C-terminus - - - 0.000000000006911 67.0
HFD3_k127_4916706_14 Transcription factor zinc-finger K09981 - - 0.0000003988 56.0
HFD3_k127_4916706_15 PFAM Outer membrane efflux protein - - - 0.0004566 43.0
HFD3_k127_4916706_2 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1172.0
HFD3_k127_4916706_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.321e-251 790.0
HFD3_k127_4916706_4 PFAM formate nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 341.0
HFD3_k127_4916706_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 323.0
HFD3_k127_4916706_6 Trypsin-like serine protease K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 309.0
HFD3_k127_4916706_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001444 258.0
HFD3_k127_4916706_8 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000003814 171.0
HFD3_k127_4916706_9 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000001647 122.0
HFD3_k127_4924450_0 lipoprotein biosynthetic process K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
HFD3_k127_4924450_1 Amidohydrolase family K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002042 282.0
HFD3_k127_4924450_2 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000009084 235.0
HFD3_k127_4924450_3 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000001539 212.0
HFD3_k127_4924450_4 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000001732 154.0
HFD3_k127_4929823_0 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 355.0
HFD3_k127_4929823_1 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004837 280.0
HFD3_k127_4929823_2 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000005168 235.0
HFD3_k127_4929823_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000003834 194.0
HFD3_k127_4946424_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 602.0
HFD3_k127_4946424_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 557.0
HFD3_k127_4946424_10 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000005406 69.0
HFD3_k127_4946424_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000001824 64.0
HFD3_k127_4946424_12 Small-conductance mechanosensitive channel - - - 0.00000003189 58.0
HFD3_k127_4946424_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 395.0
HFD3_k127_4946424_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
HFD3_k127_4946424_4 Acts as a magnesium transporter K04767,K06213,K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 378.0
HFD3_k127_4946424_5 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 345.0
HFD3_k127_4946424_6 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000003178 154.0
HFD3_k127_4946424_7 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0000000000000000000000000000000000008512 139.0
HFD3_k127_4946424_8 Phosphopantetheine attachment site - - - 0.000000000000000000008799 93.0
HFD3_k127_4946424_9 - - - - 0.000000000000000001307 90.0
HFD3_k127_4971604_0 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 516.0
HFD3_k127_4971604_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 461.0
HFD3_k127_4971604_10 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000007849 124.0
HFD3_k127_4971604_11 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000001489 125.0
HFD3_k127_4971604_12 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000001319 110.0
HFD3_k127_4971604_13 Protein of unknown function (DUF448) K07742 - - 0.0000000002295 64.0
HFD3_k127_4971604_14 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000001186 55.0
HFD3_k127_4971604_2 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 322.0
HFD3_k127_4971604_3 Tryptophanase K01667,K01668 - 4.1.99.1,4.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 321.0
HFD3_k127_4971604_4 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007989 286.0
HFD3_k127_4971604_5 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
HFD3_k127_4971604_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000008521 198.0
HFD3_k127_4971604_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000005029 178.0
HFD3_k127_4971604_8 KR domain - - - 0.00000000000000000000000000000000000000000003785 169.0
HFD3_k127_4971604_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000007828 135.0
HFD3_k127_5019573_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.579e-197 628.0
HFD3_k127_5019573_1 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 522.0
HFD3_k127_5019573_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000005537 119.0
HFD3_k127_5019573_11 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000002057 120.0
HFD3_k127_5019573_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00003872 46.0
HFD3_k127_5019573_13 Glutathione S-transferase, N-terminal domain - - - 0.0001846 44.0
HFD3_k127_5019573_14 Belongs to the GARS family K01945 GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 0.0004035 45.0
HFD3_k127_5019573_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 514.0
HFD3_k127_5019573_3 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 307.0
HFD3_k127_5019573_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
HFD3_k127_5019573_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000002333 244.0
HFD3_k127_5019573_6 AIR carboxylase K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000008536 194.0
HFD3_k127_5019573_7 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000002787 192.0
HFD3_k127_5019573_8 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000001859 169.0
HFD3_k127_5019573_9 Cupin domain - - - 0.00000000000000000000000000000000002859 141.0
HFD3_k127_5026355_0 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 503.0
HFD3_k127_5026355_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 426.0
HFD3_k127_5026355_3 Phosphopantetheine attachment site - - - 0.000000000000000003218 87.0
HFD3_k127_5059495_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 603.0
HFD3_k127_5059495_1 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 423.0
HFD3_k127_5059495_10 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000019 188.0
HFD3_k127_5059495_11 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000004065 180.0
HFD3_k127_5059495_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000001268 175.0
HFD3_k127_5059495_13 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000003637 157.0
HFD3_k127_5059495_14 SEC-C motif - - - 0.0000000000000000000001099 101.0
HFD3_k127_5059495_15 Glutathione S-Transferase K00799 - 2.5.1.18 0.000000000002068 68.0
HFD3_k127_5059495_16 Glutathione S-transferase, N-terminal domain - - - 0.000000000003251 68.0
HFD3_k127_5059495_2 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 387.0
HFD3_k127_5059495_3 Class ii aldolase K01628,K18256 - 4.1.1.69,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 353.0
HFD3_k127_5059495_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 276.0
HFD3_k127_5059495_5 DTW - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
HFD3_k127_5059495_6 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000719 205.0
HFD3_k127_5059495_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000002193 211.0
HFD3_k127_5059495_8 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000008729 203.0
HFD3_k127_5059495_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000244 190.0
HFD3_k127_5105626_0 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 460.0
HFD3_k127_5105626_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
HFD3_k127_5105626_2 TIGRFAM radical SAM Cys-rich domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 379.0
HFD3_k127_5105626_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000001468 167.0
HFD3_k127_5105626_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000002846 117.0
HFD3_k127_5112064_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 424.0
HFD3_k127_5112064_1 Isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000002542 207.0
HFD3_k127_5112064_2 enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000017 125.0
HFD3_k127_5112064_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000001542 94.0
HFD3_k127_5128709_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 586.0
HFD3_k127_5128709_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 433.0
HFD3_k127_5128709_2 2 iron, 2 sulfur cluster binding K00087,K03518,K07302,K13483 - 1.17.1.4,1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000001177 202.0
HFD3_k127_5128709_3 FAD binding domain in molybdopterin dehydrogenase K13479,K20445 - 1.17.1.4,1.17.1.5 0.00000000000000000000000000000000000000000000004761 181.0
HFD3_k127_5139870_0 Glycosyltransferase Family 4 - - - 2.862e-235 733.0
HFD3_k127_5139870_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 599.0
HFD3_k127_5139870_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 414.0
HFD3_k127_5139870_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 407.0
HFD3_k127_5139870_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000005617 138.0
HFD3_k127_5152233_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.816e-282 876.0
HFD3_k127_5152233_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 294.0
HFD3_k127_5152233_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008275 293.0
HFD3_k127_5152233_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000001228 250.0
HFD3_k127_5152233_4 YbbR-like protein - - - 0.0000000000002579 80.0
HFD3_k127_5152233_5 Tetratricopeptide repeat - - - 0.000000000004183 69.0
HFD3_k127_5152233_6 - - - - 0.000004675 49.0
HFD3_k127_51971_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 6.709e-310 969.0
HFD3_k127_51971_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 540.0
HFD3_k127_51971_10 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000004932 201.0
HFD3_k127_51971_11 proline dipeptidase activity K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000000000002971 205.0
HFD3_k127_51971_12 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000002287 141.0
HFD3_k127_51971_13 Menaquinone biosynthesis - - - 0.000000000000000008743 94.0
HFD3_k127_51971_14 Creatinase/Prolidase N-terminal domain - - - 0.0000000000001196 83.0
HFD3_k127_51971_15 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000007014 52.0
HFD3_k127_51971_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 461.0
HFD3_k127_51971_3 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 416.0
HFD3_k127_51971_4 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 374.0
HFD3_k127_51971_5 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 354.0
HFD3_k127_51971_6 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 330.0
HFD3_k127_51971_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003171 291.0
HFD3_k127_51971_8 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000664 240.0
HFD3_k127_51971_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
HFD3_k127_521124_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 541.0
HFD3_k127_521124_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 528.0
HFD3_k127_521124_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
HFD3_k127_521124_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000348 219.0
HFD3_k127_521124_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001579 195.0
HFD3_k127_521124_5 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000003116 202.0
HFD3_k127_521124_6 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000109 175.0
HFD3_k127_521124_8 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000266 75.0
HFD3_k127_521124_9 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 - 4.1.1.98 0.000000005303 58.0
HFD3_k127_5275465_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.012e-233 741.0
HFD3_k127_5275465_1 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 383.0
HFD3_k127_5275465_10 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000001039 59.0
HFD3_k127_5275465_11 NMT1-like family - - - 0.00000001793 66.0
HFD3_k127_5275465_12 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0003345 45.0
HFD3_k127_5275465_13 - - - - 0.0008007 44.0
HFD3_k127_5275465_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 357.0
HFD3_k127_5275465_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 311.0
HFD3_k127_5275465_4 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000001016 235.0
HFD3_k127_5275465_5 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000002258 198.0
HFD3_k127_5275465_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000001654 171.0
HFD3_k127_5275465_7 Methyltransferase domain - - - 0.00000000000000000000000000000000006985 142.0
HFD3_k127_5275465_8 nuclease activity K06218 - - 0.00000000000000003238 84.0
HFD3_k127_5275465_9 peptidyl-tyrosine sulfation - - - 0.000000000004026 74.0
HFD3_k127_5279191_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.284e-231 735.0
HFD3_k127_5279191_1 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 1.898e-202 652.0
HFD3_k127_5279191_10 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000001519 137.0
HFD3_k127_5279191_11 RNA recognition motif - - - 0.0000000000000000000000000000002948 125.0
HFD3_k127_5279191_12 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000000003528 119.0
HFD3_k127_5279191_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000114 96.0
HFD3_k127_5279191_14 NMT1/THI5 like K02051 - - 0.000001555 59.0
HFD3_k127_5279191_2 nitrogen compound transport K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 485.0
HFD3_k127_5279191_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 457.0
HFD3_k127_5279191_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 398.0
HFD3_k127_5279191_5 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 331.0
HFD3_k127_5279191_6 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 307.0
HFD3_k127_5279191_7 Belongs to the UPF0255 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001215 279.0
HFD3_k127_5279191_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 271.0
HFD3_k127_5279191_9 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000001133 159.0
HFD3_k127_529363_0 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 380.0
HFD3_k127_529363_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002393 238.0
HFD3_k127_529363_2 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000002422 231.0
HFD3_k127_529363_3 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000000000000000000000000000000000000000000001605 213.0
HFD3_k127_529363_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000002596 215.0
HFD3_k127_529363_5 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000006203 150.0
HFD3_k127_529363_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000006648 127.0
HFD3_k127_529363_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000007976 116.0
HFD3_k127_529363_8 Redoxin K03564 - 1.11.1.15 0.0000000000000007169 78.0
HFD3_k127_529363_9 Redoxin K03564 - 1.11.1.15 0.0000000000007462 70.0
HFD3_k127_5295666_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 319.0
HFD3_k127_5295666_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001585 242.0
HFD3_k127_5295666_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000001348 186.0
HFD3_k127_5295666_3 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000007048 128.0
HFD3_k127_5295666_4 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000001946 94.0
HFD3_k127_5295666_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000007587 83.0
HFD3_k127_5295666_6 Beta-lactamase superfamily domain - - - 0.0001278 45.0
HFD3_k127_5311334_0 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
HFD3_k127_5311334_1 Protein of unknown function (DUF1152) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004922 248.0
HFD3_k127_5311334_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004291 244.0
HFD3_k127_5311334_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000001513 201.0
HFD3_k127_5311334_4 Sulfatase K01138 - - 0.00000000000000000000000000000000000000000001483 174.0
HFD3_k127_5311334_5 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000009839 127.0
HFD3_k127_5311334_6 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000009492 122.0
HFD3_k127_5311476_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1013.0
HFD3_k127_5311476_1 Belongs to the glycosyl hydrolase 57 family - - - 7.56e-322 1005.0
HFD3_k127_5311476_2 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 1.234e-202 652.0
HFD3_k127_5311476_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 582.0
HFD3_k127_5311476_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 469.0
HFD3_k127_53520_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 1.778e-199 648.0
HFD3_k127_53520_1 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 321.0
HFD3_k127_53520_2 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000003359 169.0
HFD3_k127_53520_3 - - - - 0.000000000000000000000000001735 112.0
HFD3_k127_53520_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000007665 111.0
HFD3_k127_53520_5 - - - - 0.00000000000007684 73.0
HFD3_k127_53520_6 4Fe-4S dicluster domain - - - 0.0000000000041 70.0
HFD3_k127_53520_7 thiamine-containing compound biosynthetic process K02051 - - 0.000000002064 69.0
HFD3_k127_5366976_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2086.0
HFD3_k127_5366976_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1924.0
HFD3_k127_5366976_10 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 569.0
HFD3_k127_5366976_11 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 559.0
HFD3_k127_5366976_12 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 454.0
HFD3_k127_5366976_13 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 453.0
HFD3_k127_5366976_14 extracellular solute-binding protein, family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 430.0
HFD3_k127_5366976_15 PFAM PrpF protein K20451 - 5.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 415.0
HFD3_k127_5366976_16 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 393.0
HFD3_k127_5366976_17 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 355.0
HFD3_k127_5366976_18 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 357.0
HFD3_k127_5366976_19 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 335.0
HFD3_k127_5366976_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1080.0
HFD3_k127_5366976_20 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 332.0
HFD3_k127_5366976_21 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 335.0
HFD3_k127_5366976_22 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
HFD3_k127_5366976_23 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 325.0
HFD3_k127_5366976_24 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 307.0
HFD3_k127_5366976_25 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000144 295.0
HFD3_k127_5366976_26 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002243 276.0
HFD3_k127_5366976_27 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006503 263.0
HFD3_k127_5366976_28 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004293 263.0
HFD3_k127_5366976_29 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004829 263.0
HFD3_k127_5366976_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1078.0
HFD3_k127_5366976_30 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
HFD3_k127_5366976_31 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HFD3_k127_5366976_32 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000006979 235.0
HFD3_k127_5366976_33 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000001018 236.0
HFD3_k127_5366976_34 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000000002911 215.0
HFD3_k127_5366976_35 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001058 214.0
HFD3_k127_5366976_36 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000000000000000000000000000000000000000000000000000000000401 223.0
HFD3_k127_5366976_37 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
HFD3_k127_5366976_38 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001066 211.0
HFD3_k127_5366976_39 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000003633 227.0
HFD3_k127_5366976_4 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.939e-263 822.0
HFD3_k127_5366976_40 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000001706 214.0
HFD3_k127_5366976_41 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000003785 212.0
HFD3_k127_5366976_42 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001815 205.0
HFD3_k127_5366976_43 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001192 202.0
HFD3_k127_5366976_44 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
HFD3_k127_5366976_45 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000007379 198.0
HFD3_k127_5366976_46 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000198 203.0
HFD3_k127_5366976_47 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000001001 194.0
HFD3_k127_5366976_48 Ribosomal protein L13 K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001241 186.0
HFD3_k127_5366976_49 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000001799 178.0
HFD3_k127_5366976_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.265e-222 692.0
HFD3_k127_5366976_50 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002966 173.0
HFD3_k127_5366976_51 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000004654 171.0
HFD3_k127_5366976_52 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000681 172.0
HFD3_k127_5366976_53 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000155 179.0
HFD3_k127_5366976_54 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000003035 163.0
HFD3_k127_5366976_55 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001076 146.0
HFD3_k127_5366976_56 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001197 145.0
HFD3_k127_5366976_57 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001375 141.0
HFD3_k127_5366976_58 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002347 134.0
HFD3_k127_5366976_59 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000007282 128.0
HFD3_k127_5366976_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.036e-199 629.0
HFD3_k127_5366976_60 amine dehydrogenase activity - - - 0.0000000000000000000000000000001156 132.0
HFD3_k127_5366976_61 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000003942 124.0
HFD3_k127_5366976_62 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001051 115.0
HFD3_k127_5366976_63 response regulator K10943 - - 0.000000000000000000000000005256 128.0
HFD3_k127_5366976_64 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006413 110.0
HFD3_k127_5366976_65 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000001487 109.0
HFD3_k127_5366976_66 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000002412 96.0
HFD3_k127_5366976_67 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000003683 94.0
HFD3_k127_5366976_68 of the major facilitator superfamily - - - 0.0000000000000001875 92.0
HFD3_k127_5366976_69 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000001682 77.0
HFD3_k127_5366976_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.112e-197 623.0
HFD3_k127_5366976_71 FCD - - - 0.00000000004796 67.0
HFD3_k127_5366976_72 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000001683 65.0
HFD3_k127_5366976_73 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000006251 62.0
HFD3_k127_5366976_75 RHS Repeat - - - 0.00003421 49.0
HFD3_k127_5366976_76 VTC domain - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0000822,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006082,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006810,GO:0006914,GO:0006996,GO:0007033,GO:0007034,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009056,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016237,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019932,GO:0023052,GO:0031090,GO:0031224,GO:0031300,GO:0031310,GO:0032991,GO:0033254,GO:0035556,GO:0036094,GO:0042144,GO:0043167,GO:0043168,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0048016,GO:0048284,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0061024,GO:0061025,GO:0061919,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0097576,GO:0098588,GO:0098805,GO:0098852,GO:0101031,GO:1901576 - 0.00004019 55.0
HFD3_k127_5366976_8 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 604.0
HFD3_k127_5366976_9 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 571.0
HFD3_k127_5401806_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1443.0
HFD3_k127_5401806_10 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
HFD3_k127_5401806_11 TPR repeat - - - 0.0000000000000000000000000000000000000000000006816 177.0
HFD3_k127_5401806_12 Outer membrane efflux protein - - - 0.00000000000000000000000000000000002497 152.0
HFD3_k127_5401806_13 NMT1-like family K02051 - - 0.000000000000000000000001318 116.0
HFD3_k127_5401806_14 protein conserved in bacteria - - - 0.00000000000000000000000504 108.0
HFD3_k127_5401806_15 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000321 108.0
HFD3_k127_5401806_16 Sulfurtransferase - - - 0.000000000000000000008631 93.0
HFD3_k127_5401806_17 Transposase K07491 - - 0.0000000000000000003475 90.0
HFD3_k127_5401806_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000004047 97.0
HFD3_k127_5401806_19 Glyoxalase-like domain K08234 - - 0.00002683 55.0
HFD3_k127_5401806_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
HFD3_k127_5401806_3 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 326.0
HFD3_k127_5401806_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 286.0
HFD3_k127_5401806_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004848 275.0
HFD3_k127_5401806_6 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 267.0
HFD3_k127_5401806_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004621 271.0
HFD3_k127_5401806_8 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000007517 244.0
HFD3_k127_5401806_9 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000004352 230.0
HFD3_k127_5437075_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 2.691e-196 636.0
HFD3_k127_5437075_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 572.0
HFD3_k127_5437075_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 520.0
HFD3_k127_5437075_3 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 468.0
HFD3_k127_5437075_4 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 443.0
HFD3_k127_5437075_5 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 369.0
HFD3_k127_5437075_6 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000001067 175.0
HFD3_k127_5437075_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000008846 128.0
HFD3_k127_5437075_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000004918 108.0
HFD3_k127_5438241_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.836e-212 674.0
HFD3_k127_5438241_1 Domain of unknown function (DUF4910) - - - 5.09e-201 633.0
HFD3_k127_5438241_10 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 384.0
HFD3_k127_5438241_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 376.0
HFD3_k127_5438241_12 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 361.0
HFD3_k127_5438241_13 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
HFD3_k127_5438241_14 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
HFD3_k127_5438241_15 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 333.0
HFD3_k127_5438241_16 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 330.0
HFD3_k127_5438241_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 339.0
HFD3_k127_5438241_18 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 335.0
HFD3_k127_5438241_19 FemAB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 312.0
HFD3_k127_5438241_2 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 596.0
HFD3_k127_5438241_20 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 299.0
HFD3_k127_5438241_21 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005114 302.0
HFD3_k127_5438241_22 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
HFD3_k127_5438241_23 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001074 259.0
HFD3_k127_5438241_24 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001329 255.0
HFD3_k127_5438241_25 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007399 244.0
HFD3_k127_5438241_26 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000814 209.0
HFD3_k127_5438241_27 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000001059 194.0
HFD3_k127_5438241_28 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000225 176.0
HFD3_k127_5438241_29 Peptidase, M23 - - - 0.000000000000000000000000000000000000000002514 170.0
HFD3_k127_5438241_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 582.0
HFD3_k127_5438241_30 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000001234 149.0
HFD3_k127_5438241_31 Capsular exopolysaccharide family - - - 0.000000000000000000000000000000001936 141.0
HFD3_k127_5438241_32 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000171 114.0
HFD3_k127_5438241_34 DoxX K15977 - - 0.00000000000000000008035 95.0
HFD3_k127_5438241_35 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000004185 79.0
HFD3_k127_5438241_36 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 - - 0.0000000000000528 80.0
HFD3_k127_5438241_37 - - - - 0.00000000001941 66.0
HFD3_k127_5438241_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 514.0
HFD3_k127_5438241_5 PFAM ABC transporter related K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 505.0
HFD3_k127_5438241_6 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 489.0
HFD3_k127_5438241_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 493.0
HFD3_k127_5438241_8 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 398.0
HFD3_k127_5438241_9 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 396.0
HFD3_k127_5443268_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 2.611e-200 649.0
HFD3_k127_5443268_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 563.0
HFD3_k127_5443268_10 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000147 98.0
HFD3_k127_5443268_11 NMT1-like family K02051 GO:0003674,GO:0005215 - 0.0003196 46.0
HFD3_k127_5443268_2 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 557.0
HFD3_k127_5443268_3 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 411.0
HFD3_k127_5443268_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000133 260.0
HFD3_k127_5443268_5 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000001486 225.0
HFD3_k127_5443268_6 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000004744 169.0
HFD3_k127_5443268_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000002174 117.0
HFD3_k127_5443268_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000003632 94.0
HFD3_k127_5443268_9 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000004018 91.0
HFD3_k127_5445600_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.202e-272 847.0
HFD3_k127_5445600_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 489.0
HFD3_k127_5445600_10 Protein of unknown function (DUF507) - - - 0.000000000000000008586 86.0
HFD3_k127_5445600_2 Mur ligase, middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 456.0
HFD3_k127_5445600_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
HFD3_k127_5445600_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
HFD3_k127_5445600_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000001286 207.0
HFD3_k127_5445600_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000005467 153.0
HFD3_k127_5445600_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000002309 120.0
HFD3_k127_5445600_8 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000001083 105.0
HFD3_k127_5445600_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000009304 100.0
HFD3_k127_5446247_0 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 478.0
HFD3_k127_5446247_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 328.0
HFD3_k127_5446247_10 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000002234 120.0
HFD3_k127_5446247_11 GAF domain - - - 0.0000000000000000000000007321 116.0
HFD3_k127_5446247_12 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.000000000000002305 81.0
HFD3_k127_5446247_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K21252 - - 0.000000000001542 72.0
HFD3_k127_5446247_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
HFD3_k127_5446247_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
HFD3_k127_5446247_4 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000007517 244.0
HFD3_k127_5446247_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006913 200.0
HFD3_k127_5446247_6 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000436 167.0
HFD3_k127_5446247_7 FIST_C - - - 0.00000000000000000000000000000000000000001231 168.0
HFD3_k127_5446247_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000001748 129.0
HFD3_k127_5446247_9 Universal stress protein family - - - 0.00000000000000000000000000001213 123.0
HFD3_k127_5459591_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 536.0
HFD3_k127_5459591_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 544.0
HFD3_k127_5459591_10 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 312.0
HFD3_k127_5459591_11 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
HFD3_k127_5459591_12 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
HFD3_k127_5459591_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004862 267.0
HFD3_k127_5459591_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
HFD3_k127_5459591_15 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000000455 192.0
HFD3_k127_5459591_16 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000009907 120.0
HFD3_k127_5459591_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000008873 79.0
HFD3_k127_5459591_19 Chemotaxis protein CheY - - - 0.00000000003924 68.0
HFD3_k127_5459591_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 471.0
HFD3_k127_5459591_20 Polysaccharide lyase family 4, domain II - - - 0.00000008907 55.0
HFD3_k127_5459591_3 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 409.0
HFD3_k127_5459591_4 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 400.0
HFD3_k127_5459591_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 394.0
HFD3_k127_5459591_6 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 372.0
HFD3_k127_5459591_7 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 351.0
HFD3_k127_5459591_8 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 350.0
HFD3_k127_5459591_9 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 320.0
HFD3_k127_5476018_0 PFAM CoA-binding domain protein K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 576.0
HFD3_k127_5476018_1 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 333.0
HFD3_k127_5476018_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001982 264.0
HFD3_k127_5476018_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000513 251.0
HFD3_k127_5476018_4 Transmembrane secretion effector - - - 0.0000000000000003793 83.0
HFD3_k127_5476018_5 NMT1-like family K02051,K15553 - - 0.0000000001158 73.0
HFD3_k127_5476018_6 NMT1-like family K02051 - - 0.000005988 58.0
HFD3_k127_5480696_0 Histidine kinase-like ATPases - - - 1.338e-318 1039.0
HFD3_k127_5480696_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 476.0
HFD3_k127_5480696_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 409.0
HFD3_k127_5480696_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 359.0
HFD3_k127_5480696_4 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 293.0
HFD3_k127_5480696_5 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000002841 173.0
HFD3_k127_5480696_6 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000005865 164.0
HFD3_k127_5480696_7 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000001118 149.0
HFD3_k127_5480696_8 Response regulator, receiver K11443 - - 0.000000000000000000000000000000006594 131.0
HFD3_k127_5493178_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1090.0
HFD3_k127_5493178_1 Sigma-54 interaction domain K15836 - - 1.52e-213 684.0
HFD3_k127_5493178_10 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000867 113.0
HFD3_k127_5493178_11 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000711 111.0
HFD3_k127_5493178_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000002524 93.0
HFD3_k127_5493178_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 577.0
HFD3_k127_5493178_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 485.0
HFD3_k127_5493178_4 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 325.0
HFD3_k127_5493178_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 299.0
HFD3_k127_5493178_6 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008467 258.0
HFD3_k127_5493178_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002981 236.0
HFD3_k127_5493178_8 - - - - 0.000000000000000000000000000000000000000000000000001019 190.0
HFD3_k127_5493178_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000009004 183.0
HFD3_k127_5498969_0 membrane protein involved in D-alanine K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 518.0
HFD3_k127_5498969_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000001108 161.0
HFD3_k127_5498969_3 DinB superfamily - - - 0.00000000000000000000000003642 111.0
HFD3_k127_5498969_4 NMT1/THI5 like - - - 0.00000308 59.0
HFD3_k127_5499592_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 563.0
HFD3_k127_5499592_1 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 465.0
HFD3_k127_5499592_10 phosphinothricin N-acetyltransferase activity K03823,K18816 - 2.3.1.183,2.3.1.82 0.00000000000000000000000001901 113.0
HFD3_k127_5499592_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000001832 111.0
HFD3_k127_5499592_12 Putative phosphatase (DUF442) - - - 0.0000000000000001084 87.0
HFD3_k127_5499592_13 PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000002593 66.0
HFD3_k127_5499592_14 lactoylglutathione lyase activity - - - 0.0000001569 59.0
HFD3_k127_5499592_15 PA domain - - - 0.000007893 57.0
HFD3_k127_5499592_2 Bile acid-inducible L-carnitine dehydratase protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 379.0
HFD3_k127_5499592_3 Dehydratase K14449,K18290 - 4.2.1.148,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000007477 214.0
HFD3_k127_5499592_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000003813 207.0
HFD3_k127_5499592_5 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000003544 158.0
HFD3_k127_5499592_6 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000003386 156.0
HFD3_k127_5499592_7 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000001127 154.0
HFD3_k127_5499592_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000002113 142.0
HFD3_k127_5499592_9 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000003022 136.0
HFD3_k127_5500104_0 PAS domain K13598 - 2.7.13.3 7.912e-220 704.0
HFD3_k127_5500104_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 464.0
HFD3_k127_5500104_11 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000006899 98.0
HFD3_k127_5500104_12 Protein of unknown function (DUF2905) - - - 0.0000000000000000000347 91.0
HFD3_k127_5500104_13 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000004603 83.0
HFD3_k127_5500104_14 ornithine cyclodeaminase activity - - - 0.000000000002248 69.0
HFD3_k127_5500104_15 Transposase IS200 like K07491 - - 0.00000005937 54.0
HFD3_k127_5500104_16 parallel beta-helix repeat (two copies) - - - 0.00007285 51.0
HFD3_k127_5500104_17 - - - - 0.0007093 49.0
HFD3_k127_5500104_2 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 392.0
HFD3_k127_5500104_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 351.0
HFD3_k127_5500104_4 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 329.0
HFD3_k127_5500104_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 317.0
HFD3_k127_5500104_6 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000001566 225.0
HFD3_k127_5500104_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000131 186.0
HFD3_k127_5500104_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000004065 150.0
HFD3_k127_5500104_9 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000008415 122.0
HFD3_k127_5508099_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 448.0
HFD3_k127_5508099_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000181 155.0
HFD3_k127_5508099_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000007099 156.0
HFD3_k127_5508099_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000007933 151.0
HFD3_k127_5508099_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000103 116.0
HFD3_k127_5508099_5 membrane transporter protein K07090 - - 0.000000000000000000000000001112 122.0
HFD3_k127_552834_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 416.0
HFD3_k127_552834_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 381.0
HFD3_k127_552834_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 332.0
HFD3_k127_552834_3 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003326 238.0
HFD3_k127_552834_4 alpha/beta hydrolase fold K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
HFD3_k127_552834_5 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000007858 202.0
HFD3_k127_552834_6 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000004836 182.0
HFD3_k127_552834_7 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.00000000000000000000000000006511 128.0
HFD3_k127_552834_8 mttA/Hcf106 family K03116 - - 0.00000000000001494 75.0
HFD3_k127_552834_9 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000004635 68.0
HFD3_k127_5567350_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.313e-289 894.0
HFD3_k127_5567350_1 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672,K21579 - 1.21.4.2,1.21.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 298.0
HFD3_k127_5567350_10 Adenylate - - - 0.000001493 56.0
HFD3_k127_5567350_11 PFAM Glycine sarcosine betaine reductase component B subunits - - - 0.00001248 50.0
HFD3_k127_5567350_12 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00006996 53.0
HFD3_k127_5567350_2 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001324 252.0
HFD3_k127_5567350_3 PFAM Glycine sarcosine betaine reductase component B subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008362 259.0
HFD3_k127_5567350_4 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HFD3_k127_5567350_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000001177 200.0
HFD3_k127_5567350_6 methyltransferase - - - 0.000000000000000000000000000000000000001053 160.0
HFD3_k127_5567350_7 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.0000000000000000000193 93.0
HFD3_k127_5567350_8 ABC transporter substrate-binding protein K15551 - - 0.0000000000001815 81.0
HFD3_k127_5567350_9 - - - - 0.0000000000009076 70.0
HFD3_k127_5572818_0 RnfC Barrel sandwich hybrid domain K20140 - 6.4.1.7 8.459e-206 649.0
HFD3_k127_5572818_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 572.0
HFD3_k127_5572818_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 425.0
HFD3_k127_5572818_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000197 216.0
HFD3_k127_5572818_4 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000001559 113.0
HFD3_k127_5572818_5 nitrite transmembrane transporter activity - - - 0.0000000000000000001587 101.0
HFD3_k127_5572818_6 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000008188 78.0
HFD3_k127_5572818_7 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000946 44.0
HFD3_k127_5585586_0 Ammonium Transporter Family K03320 - - 5.223e-212 670.0
HFD3_k127_5585586_1 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 519.0
HFD3_k127_5585586_2 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
HFD3_k127_5585586_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000003095 188.0
HFD3_k127_5585586_4 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000001714 175.0
HFD3_k127_5585586_5 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000153 96.0
HFD3_k127_5594153_0 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000474 233.0
HFD3_k127_5594153_2 VirC1 protein K03496 - - 0.00000000000000008238 90.0
HFD3_k127_5594153_3 NAD(P)H-binding - - - 0.0000003872 55.0
HFD3_k127_5594153_4 - - - - 0.000003143 56.0
HFD3_k127_5611419_0 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 606.0
HFD3_k127_5611419_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 308.0
HFD3_k127_5611419_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 303.0
HFD3_k127_5611419_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000115 214.0
HFD3_k127_5611419_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000012 202.0
HFD3_k127_5611419_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000002743 174.0
HFD3_k127_5616686_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 474.0
HFD3_k127_5616686_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 411.0
HFD3_k127_5616686_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 316.0
HFD3_k127_5616686_3 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
HFD3_k127_5616686_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000003936 187.0
HFD3_k127_5616686_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000005879 177.0
HFD3_k127_5616686_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000002177 159.0
HFD3_k127_5616686_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000001143 154.0
HFD3_k127_5616686_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000004912 129.0
HFD3_k127_5625975_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 422.0
HFD3_k127_5625975_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004278 256.0
HFD3_k127_5625975_10 OsmC-like protein - - - 0.0001026 48.0
HFD3_k127_5625975_2 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000001736 241.0
HFD3_k127_5625975_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000001069 211.0
HFD3_k127_5625975_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000001778 189.0
HFD3_k127_5625975_5 Thioredoxin K03671,K05838 - - 0.000000000000000000000000000000000000000000000002747 177.0
HFD3_k127_5625975_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000004148 151.0
HFD3_k127_5625975_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000000002629 88.0
HFD3_k127_5625975_8 OsmC-like protein - - - 0.00000000001881 66.0
HFD3_k127_5625975_9 ABC transporter substrate binding protein K01989 - - 0.000006013 48.0
HFD3_k127_5653280_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.664e-203 644.0
HFD3_k127_5653280_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 426.0
HFD3_k127_5653280_2 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 383.0
HFD3_k127_5653280_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 294.0
HFD3_k127_5653280_4 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004121 254.0
HFD3_k127_5653280_5 Tetratricopeptide - - - 0.0001189 51.0
HFD3_k127_5653877_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 320.0
HFD3_k127_5653877_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000004033 190.0
HFD3_k127_5653877_2 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000003872 158.0
HFD3_k127_5653877_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000001304 157.0
HFD3_k127_5653877_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000004584 144.0
HFD3_k127_5653877_5 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.000000000000000000000000001669 119.0
HFD3_k127_5653877_6 oxidation-reduction process - - - 0.000000000000000000000518 101.0
HFD3_k127_5653877_7 NMT1-like family - - - 0.0000000000000000000007231 108.0
HFD3_k127_5679250_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.525e-279 879.0
HFD3_k127_5679250_1 Aldehyde dehydrogenase family K00131 - 1.2.1.9 1.012e-221 695.0
HFD3_k127_5679250_10 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
HFD3_k127_5679250_11 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 316.0
HFD3_k127_5679250_12 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
HFD3_k127_5679250_13 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 302.0
HFD3_k127_5679250_14 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001598 286.0
HFD3_k127_5679250_15 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004969 288.0
HFD3_k127_5679250_16 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 267.0
HFD3_k127_5679250_17 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000002965 241.0
HFD3_k127_5679250_18 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
HFD3_k127_5679250_19 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000007652 220.0
HFD3_k127_5679250_2 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 607.0
HFD3_k127_5679250_20 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000002816 214.0
HFD3_k127_5679250_21 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001216 208.0
HFD3_k127_5679250_22 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000002 207.0
HFD3_k127_5679250_23 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000001718 197.0
HFD3_k127_5679250_24 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000008434 196.0
HFD3_k127_5679250_25 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000007628 181.0
HFD3_k127_5679250_26 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000005707 178.0
HFD3_k127_5679250_27 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000008963 156.0
HFD3_k127_5679250_28 YGGT family K02221 - - 0.00000000000000000000000000002692 121.0
HFD3_k127_5679250_29 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000001913 95.0
HFD3_k127_5679250_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 588.0
HFD3_k127_5679250_30 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000004616 96.0
HFD3_k127_5679250_31 d-proline reductase K10794 - 1.21.4.1 0.0000000000000001841 86.0
HFD3_k127_5679250_32 - - - - 0.0000000000000002379 84.0
HFD3_k127_5679250_33 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000008796 77.0
HFD3_k127_5679250_34 - - - - 0.00000000005829 66.0
HFD3_k127_5679250_35 thiamine-containing compound biosynthetic process K02051 - - 0.0000000001237 74.0
HFD3_k127_5679250_36 hydroperoxide reductase activity K07486 - - 0.000000009909 60.0
HFD3_k127_5679250_37 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000001912 55.0
HFD3_k127_5679250_4 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 550.0
HFD3_k127_5679250_40 EamA-like transporter family K08978 - - 0.00004531 56.0
HFD3_k127_5679250_5 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 423.0
HFD3_k127_5679250_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 373.0
HFD3_k127_5679250_7 TIGRFAM CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 366.0
HFD3_k127_5679250_8 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 353.0
HFD3_k127_5679250_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 329.0
HFD3_k127_5684117_0 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 2.759e-229 721.0
HFD3_k127_5684117_1 Belongs to the UbiD family K01612 - 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 361.0
HFD3_k127_5684117_2 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 333.0
HFD3_k127_5684117_3 Amidohydrolase - - - 0.00000000000000000000000000003997 129.0
HFD3_k127_5684117_4 NMT1-like family - - - 0.00000000000002324 84.0
HFD3_k127_5693373_0 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 466.0
HFD3_k127_5693373_1 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 371.0
HFD3_k127_5693373_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007053 255.0
HFD3_k127_5693373_3 Amino acid permease - - - 0.0000000000000000000000000000000000000009032 153.0
HFD3_k127_5693373_4 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000001846 143.0
HFD3_k127_5693373_5 DsbA oxidoreductase - - - 0.0000000000000000000000000000002035 130.0
HFD3_k127_5693373_6 NMT1-like family K02051 - - 0.000000000000000001811 97.0
HFD3_k127_5693373_7 PFAM UspA domain protein - - - 0.00000000000000192 82.0
HFD3_k127_5696390_0 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 442.0
HFD3_k127_5696390_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 314.0
HFD3_k127_5696390_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002514 250.0
HFD3_k127_5696390_3 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000002059 232.0
HFD3_k127_5696390_4 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000001207 198.0
HFD3_k127_5696390_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001367 198.0
HFD3_k127_5696390_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000003895 191.0
HFD3_k127_5696390_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000004467 186.0
HFD3_k127_5696390_8 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000007788 180.0
HFD3_k127_5696390_9 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000006231 177.0
HFD3_k127_5696710_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 560.0
HFD3_k127_5696710_1 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 567.0
HFD3_k127_5696710_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002504 277.0
HFD3_k127_5696710_11 PFAM Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002221 247.0
HFD3_k127_5696710_12 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.000000000000000000000000000000000000002581 151.0
HFD3_k127_5696710_13 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000001636 132.0
HFD3_k127_5696710_14 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000004258 123.0
HFD3_k127_5696710_15 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000001293 118.0
HFD3_k127_5696710_16 antisigma factor binding - - - 0.0000000001148 67.0
HFD3_k127_5696710_17 Evidence 5 No homology to any previously reported sequences - - - 0.0000000005531 64.0
HFD3_k127_5696710_2 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 470.0
HFD3_k127_5696710_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 460.0
HFD3_k127_5696710_4 Divalent cation transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 435.0
HFD3_k127_5696710_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 401.0
HFD3_k127_5696710_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 344.0
HFD3_k127_5696710_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 346.0
HFD3_k127_5696710_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 346.0
HFD3_k127_5696710_9 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 296.0
HFD3_k127_5703400_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 8.73e-251 783.0
HFD3_k127_5703400_1 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 431.0
HFD3_k127_5703400_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000005581 270.0
HFD3_k127_5703400_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000008925 221.0
HFD3_k127_5703400_4 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000001382 162.0
HFD3_k127_5703400_5 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000000000000004041 148.0
HFD3_k127_5703400_6 Protein conserved in bacteria - - - 0.00000000000000000000000007768 112.0
HFD3_k127_5703400_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000001634 94.0
HFD3_k127_5703400_8 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000075 73.0
HFD3_k127_5703400_9 Phage integrase, N-terminal SAM-like domain - - - 0.0005303 44.0
HFD3_k127_5718339_0 Amino acid adenylation domain - - - 3.164e-247 781.0
HFD3_k127_5718339_1 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000002435 251.0
HFD3_k127_5718339_2 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000157 202.0
HFD3_k127_5718339_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000156 166.0
HFD3_k127_5718339_4 cellulose binding - - - 0.0000000000000000000000000000001279 138.0
HFD3_k127_5721325_0 PFAM FAD linked oxidase domain protein - - - 3.976e-307 965.0
HFD3_k127_5721325_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 591.0
HFD3_k127_5721325_2 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
HFD3_k127_5721325_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000005916 70.0
HFD3_k127_5760263_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 436.0
HFD3_k127_5760263_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 314.0
HFD3_k127_5760263_10 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000006537 111.0
HFD3_k127_5760263_11 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000008466 104.0
HFD3_k127_5760263_12 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.000000000000000000002104 96.0
HFD3_k127_5760263_13 Putative zinc-finger - - - 0.00007714 53.0
HFD3_k127_5760263_14 Protein of unknown function (DUF3106) - - - 0.0005125 48.0
HFD3_k127_5760263_2 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 301.0
HFD3_k127_5760263_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
HFD3_k127_5760263_4 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HFD3_k127_5760263_5 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000002157 198.0
HFD3_k127_5760263_6 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000849 199.0
HFD3_k127_5760263_7 NADPH-dependent f420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000005644 161.0
HFD3_k127_5760263_8 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000004237 153.0
HFD3_k127_5760263_9 Sigma-70 region 2 K03088 - - 0.000000000000000000000000008776 117.0
HFD3_k127_5774441_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 5.145e-227 737.0
HFD3_k127_5774441_1 PFAM cytochrome c oxidase, subunit I K02274 - 1.9.3.1 3.165e-199 637.0
HFD3_k127_5774441_10 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000001095 145.0
HFD3_k127_5774441_11 GYD domain - - - 0.000000000000000000000000003896 113.0
HFD3_k127_5774441_12 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000001692 116.0
HFD3_k127_5774441_13 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000000002446 87.0
HFD3_k127_5774441_15 GYD domain - - - 0.000000000002633 70.0
HFD3_k127_5774441_16 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000001911 67.0
HFD3_k127_5774441_17 Fic/DOC family - - - 0.00002578 47.0
HFD3_k127_5774441_18 - - - - 0.0008021 51.0
HFD3_k127_5774441_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 569.0
HFD3_k127_5774441_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 356.0
HFD3_k127_5774441_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
HFD3_k127_5774441_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 350.0
HFD3_k127_5774441_6 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 352.0
HFD3_k127_5774441_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
HFD3_k127_5774441_8 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000003533 160.0
HFD3_k127_5774441_9 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.0000000000000000000000000000000000000004986 153.0
HFD3_k127_5780604_0 Heat shock 70 kDa protein K04043 - - 2.78e-243 767.0
HFD3_k127_5780604_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 555.0
HFD3_k127_5780604_10 Protein involved in outer membrane biogenesis - - - 0.000000000000000005493 87.0
HFD3_k127_5780604_11 - - - - 0.0000000000000003421 88.0
HFD3_k127_5780604_12 - - - - 0.000000000000001124 82.0
HFD3_k127_5780604_13 Protein involved in outer membrane biogenesis - - - 0.00000000000009435 75.0
HFD3_k127_5780604_14 Bacterial protein of unknown function (DUF883) - - - 0.0000000000003606 74.0
HFD3_k127_5780604_2 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 515.0
HFD3_k127_5780604_3 PFAM Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 379.0
HFD3_k127_5780604_4 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 377.0
HFD3_k127_5780604_5 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000295 248.0
HFD3_k127_5780604_6 ZIP Zinc transporter - - - 0.00000000000000000000000000000000000000000000162 175.0
HFD3_k127_5780604_7 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000001303 158.0
HFD3_k127_5780604_8 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000003698 128.0
HFD3_k127_5780604_9 iron ion homeostasis K02012 - - 0.0000000000000000000004504 110.0
HFD3_k127_5804078_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.547e-238 746.0
HFD3_k127_5804078_1 transport system fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 524.0
HFD3_k127_5804078_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000005595 206.0
HFD3_k127_5804078_3 TRAP transporter solute receptor TAXI family protein K07080 - - 0.0000000000000000000000000000000000000000006443 171.0
HFD3_k127_5805520_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1214.0
HFD3_k127_5805520_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 537.0
HFD3_k127_5805520_10 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
HFD3_k127_5805520_11 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004399 243.0
HFD3_k127_5805520_12 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000001069 182.0
HFD3_k127_5805520_13 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000005685 154.0
HFD3_k127_5805520_14 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000000000000000000000000000000000001969 149.0
HFD3_k127_5805520_15 Thioredoxin-like - - - 0.000000000000000000000000000001319 129.0
HFD3_k127_5805520_16 PFAM response regulator receiver - - - 0.000000000000000000000001873 108.0
HFD3_k127_5805520_17 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000000000005683 93.0
HFD3_k127_5805520_18 Smr domain - - - 0.00000007177 59.0
HFD3_k127_5805520_19 shape-determining protein K03571 - - 0.0002177 51.0
HFD3_k127_5805520_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 548.0
HFD3_k127_5805520_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 484.0
HFD3_k127_5805520_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 383.0
HFD3_k127_5805520_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 376.0
HFD3_k127_5805520_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 368.0
HFD3_k127_5805520_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000257 286.0
HFD3_k127_5805520_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006089 267.0
HFD3_k127_5805520_9 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000007447 244.0
HFD3_k127_5820802_0 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000004466 105.0
HFD3_k127_5820802_1 AMP binding - - - 0.0000000001983 63.0
HFD3_k127_5820802_2 NMT1 THI5-like protein - - - 0.000000003843 69.0
HFD3_k127_5820802_3 Transposase IS200 like - - - 0.00007066 46.0
HFD3_k127_58314_0 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 582.0
HFD3_k127_58314_1 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 317.0
HFD3_k127_58314_2 DNA sulfur modification protein DndB K19169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002077 263.0
HFD3_k127_58314_3 GYD domain - - - 0.0001919 44.0
HFD3_k127_5841215_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1126.0
HFD3_k127_5841215_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.37e-304 947.0
HFD3_k127_5841215_10 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002329 238.0
HFD3_k127_5841215_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001288 216.0
HFD3_k127_5841215_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000004289 203.0
HFD3_k127_5841215_13 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000005976 205.0
HFD3_k127_5841215_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000002711 205.0
HFD3_k127_5841215_15 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000003577 174.0
HFD3_k127_5841215_16 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000114 164.0
HFD3_k127_5841215_17 s1 p1 nuclease K05986 - 3.1.30.1 0.0000000000000000000000000000000000000001171 162.0
HFD3_k127_5841215_18 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000002261 144.0
HFD3_k127_5841215_19 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.00000000000000000000000000000000007 142.0
HFD3_k127_5841215_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.797e-198 623.0
HFD3_k127_5841215_20 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000002621 137.0
HFD3_k127_5841215_21 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000008825 108.0
HFD3_k127_5841215_22 Lipopolysaccharide-assembly - - - 0.000000000000001184 85.0
HFD3_k127_5841215_23 Binds directly to 16S ribosomal RNA K02968 - - 0.0000008499 57.0
HFD3_k127_5841215_24 - - - - 0.000001335 53.0
HFD3_k127_5841215_25 - - - - 0.0004455 46.0
HFD3_k127_5841215_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 471.0
HFD3_k127_5841215_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 349.0
HFD3_k127_5841215_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 310.0
HFD3_k127_5841215_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HFD3_k127_5841215_7 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 288.0
HFD3_k127_5841215_8 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
HFD3_k127_5841215_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005078 281.0
HFD3_k127_5868009_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 552.0
HFD3_k127_5868009_1 all-trans-retinol 13,14-reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 417.0
HFD3_k127_5868009_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 369.0
HFD3_k127_5868009_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 320.0
HFD3_k127_5868009_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 271.0
HFD3_k127_5868009_5 nuclease activity - - - 0.0000000000000000009136 91.0
HFD3_k127_5868137_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000001234 212.0
HFD3_k127_5868137_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001434 209.0
HFD3_k127_5868137_3 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.000000000000000000000000004458 113.0
HFD3_k127_5868137_4 NMT1-like family K02051 - - 0.00000000001983 76.0
HFD3_k127_5868137_5 PFAM Transposase IS200 like K07491 - - 0.00000002676 57.0
HFD3_k127_5869642_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 404.0
HFD3_k127_5869642_1 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000008817 238.0
HFD3_k127_5869642_2 Zn-dependent hydrolases of the - - - 0.0000000000000000000000000000001212 135.0
HFD3_k127_5869642_3 PFAM Amidohydrolase 2 K03392,K07045 - 4.1.1.45 0.00000000000000000000000000003509 123.0
HFD3_k127_5869642_4 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0001187 55.0
HFD3_k127_58764_0 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000004455 185.0
HFD3_k127_58764_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000007577 166.0
HFD3_k127_58764_3 Zn peptidase - - - 0.00000000000000000000000000000001468 143.0
HFD3_k127_5878034_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 579.0
HFD3_k127_5878034_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 394.0
HFD3_k127_5878034_2 PFAM Transketolase central region K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 383.0
HFD3_k127_5878034_3 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 374.0
HFD3_k127_5878034_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
HFD3_k127_5878034_5 PFAM dehydrogenase, E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 298.0
HFD3_k127_5878034_6 EamA-like transporter family - - - 0.000000000000001307 88.0
HFD3_k127_5878034_7 NMT1-like family K02051 - - 0.000000000000005758 88.0
HFD3_k127_5878034_8 NMT1-like family K02051 - - 0.00000000000003624 83.0
HFD3_k127_5887477_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.803e-255 797.0
HFD3_k127_5887477_1 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 364.0
HFD3_k127_5887477_2 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 355.0
HFD3_k127_5887477_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000004239 152.0
HFD3_k127_5887477_4 - - - - 0.0000000000000000006593 89.0
HFD3_k127_5887477_5 Zincin-like metallopeptidase - - - 0.0000000000000000009006 88.0
HFD3_k127_5887477_6 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000143 51.0
HFD3_k127_5901038_0 PFAM ABC transporter related K06020 - 3.6.3.25 3.695e-294 910.0
HFD3_k127_5901038_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 389.0
HFD3_k127_5901038_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000118 211.0
HFD3_k127_5901038_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000004237 153.0
HFD3_k127_5901038_4 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000008708 108.0
HFD3_k127_5901038_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000002422 96.0
HFD3_k127_5901038_6 NMT1-like family K02051 - - 0.00000000000000001887 94.0
HFD3_k127_5901038_7 Protein of unknown function (DUF2442) - - - 0.0000000000000000227 85.0
HFD3_k127_5901038_9 - - - - 0.000003188 52.0
HFD3_k127_5920945_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 1.143e-206 662.0
HFD3_k127_5920945_1 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 1.788e-196 627.0
HFD3_k127_5920945_10 NMT1-like family K02051 - - 0.0000000000003324 81.0
HFD3_k127_5920945_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 324.0
HFD3_k127_5920945_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 307.0
HFD3_k127_5920945_4 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000004368 209.0
HFD3_k127_5920945_5 proline dipeptidase activity K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000006269 186.0
HFD3_k127_5920945_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000001375 183.0
HFD3_k127_5920945_7 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000002159 173.0
HFD3_k127_5920945_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000001764 136.0
HFD3_k127_5920945_9 - - - - 0.00000000000007185 84.0
HFD3_k127_5943184_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 2.506e-206 647.0
HFD3_k127_5943184_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 586.0
HFD3_k127_5943184_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000002321 120.0
HFD3_k127_5943184_11 Belongs to the Pirin family K06911 - - 0.00000000000000000000007406 101.0
HFD3_k127_5943184_12 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000004803 105.0
HFD3_k127_5943184_13 N-6 DNA Methylase K03427 - 2.1.1.72 0.000000003667 59.0
HFD3_k127_5943184_2 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 550.0
HFD3_k127_5943184_3 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 518.0
HFD3_k127_5943184_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000000000000000000000009314 211.0
HFD3_k127_5943184_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.00000000000000000000000000000000000000000000000000000000004674 209.0
HFD3_k127_5943184_6 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000387 185.0
HFD3_k127_5943184_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000141 178.0
HFD3_k127_597513_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000002204 228.0
HFD3_k127_597513_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000008527 209.0
HFD3_k127_597513_2 TRAP transporter solute receptor TAXI family protein K07080 - - 0.00000000000000000000000000000000000000000000009006 182.0
HFD3_k127_597513_3 NMT1-like family K02051 - - 0.0000000000000003056 90.0
HFD3_k127_597513_4 Amidohydrolase - - - 0.000000000000003107 87.0
HFD3_k127_597513_5 NMT1-like family - - - 0.0000000000202 75.0
HFD3_k127_6043175_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.43e-322 1007.0
HFD3_k127_6043175_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 339.0
HFD3_k127_6043175_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 336.0
HFD3_k127_6043175_3 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000121 171.0
HFD3_k127_6043175_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000001054 154.0
HFD3_k127_6043175_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000004083 152.0
HFD3_k127_6043175_6 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.00000000000000000000000000000000005898 139.0
HFD3_k127_6043175_7 Zn-dependent hydrolases of the - - - 0.00000000000000000000000000000001699 139.0
HFD3_k127_6086556_0 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 392.0
HFD3_k127_6086556_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 340.0
HFD3_k127_6086556_2 PFAM ABC transporter K02010,K02017,K02062,K10112,K10199,K17314 - 3.6.3.29,3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 309.0
HFD3_k127_6086556_3 Abc transporter K02012 - - 0.0000000000000000000009787 108.0
HFD3_k127_6086556_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000002635 55.0
HFD3_k127_61111_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1951.0
HFD3_k127_61111_1 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000001964 152.0
HFD3_k127_61111_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000234 106.0
HFD3_k127_611415_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 364.0
HFD3_k127_611415_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 347.0
HFD3_k127_611415_2 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.000000000000000000000000000000000008933 146.0
HFD3_k127_611415_3 Protein of unknown function (DUF1343) - - - 0.000000000000000000000001184 103.0
HFD3_k127_611415_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000007302 86.0
HFD3_k127_611415_5 Cupin domain - - - 0.00000000004905 70.0
HFD3_k127_6130439_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 8.523e-198 627.0
HFD3_k127_6130439_1 40-residue yvtn family beta-propeller repeat protein - - - 6.803e-196 619.0
HFD3_k127_6130439_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 290.0
HFD3_k127_6130439_11 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000006148 252.0
HFD3_k127_6130439_12 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
HFD3_k127_6130439_13 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000003077 171.0
HFD3_k127_6130439_14 ECF sigma factor - - - 0.00000000000000000000000000000000000000003443 158.0
HFD3_k127_6130439_15 COG0666 FOG Ankyrin repeat - - - 0.00000000000000000000000000000000000003611 149.0
HFD3_k127_6130439_16 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000002822 144.0
HFD3_k127_6130439_17 PFAM Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000004556 145.0
HFD3_k127_6130439_18 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000002052 125.0
HFD3_k127_6130439_19 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000009833 120.0
HFD3_k127_6130439_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 557.0
HFD3_k127_6130439_20 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000003621 96.0
HFD3_k127_6130439_21 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.00000000000000006462 94.0
HFD3_k127_6130439_22 beta-lactamase activity - - - 0.0000000000000002558 83.0
HFD3_k127_6130439_23 Protein of unknown function (DUF3426) - - - 0.0000000000000003751 91.0
HFD3_k127_6130439_24 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000002842 84.0
HFD3_k127_6130439_25 TIGRFAM TonB K03832 - - 0.0000000000001027 81.0
HFD3_k127_6130439_26 - - - - 0.000000000005531 71.0
HFD3_k127_6130439_27 - - - - 0.0000000052 65.0
HFD3_k127_6130439_28 Cytochrome C' - - - 0.00000003556 57.0
HFD3_k127_6130439_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.000000313 55.0
HFD3_k127_6130439_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 466.0
HFD3_k127_6130439_30 Putative zinc-finger - - - 0.0001659 51.0
HFD3_k127_6130439_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 435.0
HFD3_k127_6130439_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 426.0
HFD3_k127_6130439_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 418.0
HFD3_k127_6130439_7 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 379.0
HFD3_k127_6130439_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
HFD3_k127_6130439_9 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 308.0
HFD3_k127_6158775_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
HFD3_k127_6158775_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000008483 218.0
HFD3_k127_6158775_2 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000002504 142.0
HFD3_k127_6158775_4 Protein of unknown function (DUF433) - - - 0.00000000000000000008395 95.0
HFD3_k127_6158775_5 nucleotidyltransferase activity K07076 - - 0.000000000000000004298 87.0
HFD3_k127_6158775_6 Type III restriction protein res subunit K01153 - 3.1.21.3 0.00000000000006306 76.0
HFD3_k127_6158775_7 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000004698 65.0
HFD3_k127_6158775_8 HEPN domain - - - 0.0000143 51.0
HFD3_k127_6200429_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 4.611e-278 870.0
HFD3_k127_6200429_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 575.0
HFD3_k127_6200429_10 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 312.0
HFD3_k127_6200429_11 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 289.0
HFD3_k127_6200429_12 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000582 280.0
HFD3_k127_6200429_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000004382 221.0
HFD3_k127_6200429_14 Antibiotic biosynthesis monooxygenase K09932 - - 0.000000000000000000000000000000000000000000000000000313 190.0
HFD3_k127_6200429_15 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000001096 173.0
HFD3_k127_6200429_16 Evidence 4 Homologs of previously reported genes of K15977 - - 0.00000000000000000000000000000000000000000001698 166.0
HFD3_k127_6200429_17 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000004832 151.0
HFD3_k127_6200429_18 SURF4 family K15977 - - 0.000000000000000000000000000000000019 139.0
HFD3_k127_6200429_19 NMT1-like family - - - 0.000000000000000000000000000000001333 142.0
HFD3_k127_6200429_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 449.0
HFD3_k127_6200429_20 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000004573 139.0
HFD3_k127_6200429_21 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000001125 139.0
HFD3_k127_6200429_22 NMT1-like family - - - 0.000000000000000000000000000005752 132.0
HFD3_k127_6200429_23 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000001117 127.0
HFD3_k127_6200429_24 DoxX K15977 - - 0.00000000000000006616 87.0
HFD3_k127_6200429_25 NMT1/THI5 like K02051 - - 0.00000000000000006762 93.0
HFD3_k127_6200429_26 NMT1-like family K02051 - - 0.000000000001017 79.0
HFD3_k127_6200429_27 PFAM Amino acid-binding ACT K03567 - - 0.000000145 54.0
HFD3_k127_6200429_3 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 415.0
HFD3_k127_6200429_4 PFAM amidohydrolase K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 396.0
HFD3_k127_6200429_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
HFD3_k127_6200429_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 374.0
HFD3_k127_6200429_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 343.0
HFD3_k127_6200429_8 sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 359.0
HFD3_k127_6200429_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 348.0
HFD3_k127_6200540_0 MAPEG family - - - 0.000000000000000000000000003104 114.0
HFD3_k127_6200540_1 diguanylate cyclase - - - 0.0000000000006733 75.0
HFD3_k127_6200540_2 - - - - 0.000000000002722 73.0
HFD3_k127_6200540_3 NMT1/THI5 like K02051 - - 0.000000000004278 78.0
HFD3_k127_6200540_4 ABC transporter substrate binding protein K01989 - - 0.00008558 47.0
HFD3_k127_6217380_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 377.0
HFD3_k127_6217380_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
HFD3_k127_6217380_2 Alkylhydroperoxidase AhpD family core domain-containing protein 7 - - - 0.0000000000000000000000000000000001061 140.0
HFD3_k127_6217380_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000983 139.0
HFD3_k127_6224586_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 361.0
HFD3_k127_6224586_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
HFD3_k127_6224586_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K16079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.00000000000000000000000000000000001421 144.0
HFD3_k127_6224586_3 Dodecin K09165 - - 0.00000000000000002653 83.0
HFD3_k127_6224586_4 Glycosyl transferase 4-like domain - - - 0.000000000000001451 79.0
HFD3_k127_6225965_0 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 6.869e-288 895.0
HFD3_k127_6225965_1 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 399.0
HFD3_k127_6225965_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
HFD3_k127_6225965_3 Circadian clock protein KaiC K08482 - - 0.000000000005092 72.0
HFD3_k127_6230982_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 310.0
HFD3_k127_6230982_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001406 274.0
HFD3_k127_6230982_2 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000002896 242.0
HFD3_k127_6230982_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000001931 130.0
HFD3_k127_6230982_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000003461 109.0
HFD3_k127_6230982_5 NMT1-like family K02051 - - 0.000000000000000003757 93.0
HFD3_k127_6241486_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 566.0
HFD3_k127_6241486_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 522.0
HFD3_k127_6241486_10 Aerotolerance regulator N-terminal - - - 0.000002841 50.0
HFD3_k127_6241486_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 375.0
HFD3_k127_6241486_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 293.0
HFD3_k127_6241486_4 photoreceptor activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001965 294.0
HFD3_k127_6241486_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000009766 237.0
HFD3_k127_6241486_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000004114 173.0
HFD3_k127_6241486_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000003259 118.0
HFD3_k127_6241486_8 Glycine cleavage H-protein - - - 0.0000000000000008292 81.0
HFD3_k127_6241486_9 - - - - 0.0000000000005406 72.0
HFD3_k127_6253957_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 494.0
HFD3_k127_6253957_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 432.0
HFD3_k127_6253957_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 438.0
HFD3_k127_6253957_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 364.0
HFD3_k127_6253957_4 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000001194 144.0
HFD3_k127_6253957_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000001148 108.0
HFD3_k127_6263371_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.356e-256 796.0
HFD3_k127_6263371_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.807e-243 759.0
HFD3_k127_6263371_10 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000005663 95.0
HFD3_k127_6263371_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000006597 91.0
HFD3_k127_6263371_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000118 75.0
HFD3_k127_6263371_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000005228 63.0
HFD3_k127_6263371_14 thiamine-containing compound biosynthetic process K02051,K15551,K15556 - - 0.00001791 49.0
HFD3_k127_6263371_2 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 572.0
HFD3_k127_6263371_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 287.0
HFD3_k127_6263371_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000002414 139.0
HFD3_k127_6263371_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000002772 130.0
HFD3_k127_6263371_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000005836 123.0
HFD3_k127_6263371_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000002584 104.0
HFD3_k127_6264640_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.855e-245 775.0
HFD3_k127_6264640_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 442.0
HFD3_k127_6264640_10 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000000001751 134.0
HFD3_k127_6264640_11 PFAM glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000008392 115.0
HFD3_k127_6264640_12 Transcription factor zinc-finger K09981 - - 0.000000000000000004003 93.0
HFD3_k127_6264640_13 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000002142 68.0
HFD3_k127_6264640_14 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000001555 75.0
HFD3_k127_6264640_15 haloacid dehalogenase-like hydrolase - - - 0.00007694 53.0
HFD3_k127_6264640_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
HFD3_k127_6264640_3 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000005491 213.0
HFD3_k127_6264640_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000003388 217.0
HFD3_k127_6264640_5 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000001153 203.0
HFD3_k127_6264640_6 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000002803 189.0
HFD3_k127_6264640_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000003448 169.0
HFD3_k127_6264640_8 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000008368 164.0
HFD3_k127_6264640_9 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000001016 146.0
HFD3_k127_6265931_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1202.0
HFD3_k127_6265931_1 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1141.0
HFD3_k127_6265931_10 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 480.0
HFD3_k127_6265931_11 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 463.0
HFD3_k127_6265931_12 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 449.0
HFD3_k127_6265931_13 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 446.0
HFD3_k127_6265931_14 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 442.0
HFD3_k127_6265931_15 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 430.0
HFD3_k127_6265931_16 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 417.0
HFD3_k127_6265931_17 histidine ammonia-lyase K10775 - 4.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 403.0
HFD3_k127_6265931_18 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 386.0
HFD3_k127_6265931_19 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 376.0
HFD3_k127_6265931_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.712e-268 842.0
HFD3_k127_6265931_20 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 364.0
HFD3_k127_6265931_21 Peptidase family M28 K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 360.0
HFD3_k127_6265931_22 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 336.0
HFD3_k127_6265931_23 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
HFD3_k127_6265931_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008548 269.0
HFD3_k127_6265931_25 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002834 273.0
HFD3_k127_6265931_26 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000002206 243.0
HFD3_k127_6265931_27 Divergent AAA domain protein K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001328 231.0
HFD3_k127_6265931_28 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000001055 208.0
HFD3_k127_6265931_29 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000116 199.0
HFD3_k127_6265931_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.009e-227 721.0
HFD3_k127_6265931_30 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000001509 190.0
HFD3_k127_6265931_31 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000001326 181.0
HFD3_k127_6265931_32 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000004084 171.0
HFD3_k127_6265931_33 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000275 169.0
HFD3_k127_6265931_34 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001641 145.0
HFD3_k127_6265931_35 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000002134 142.0
HFD3_k127_6265931_36 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000001482 117.0
HFD3_k127_6265931_37 NUDIX domain K03574 - 3.6.1.55 0.00000000000000004091 89.0
HFD3_k127_6265931_38 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001367 80.0
HFD3_k127_6265931_4 ABC transporter K15738 - - 2.532e-217 692.0
HFD3_k127_6265931_40 Dimerisation domain - - - 0.00000114 54.0
HFD3_k127_6265931_5 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 3.389e-209 671.0
HFD3_k127_6265931_6 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 591.0
HFD3_k127_6265931_7 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 550.0
HFD3_k127_6265931_8 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 498.0
HFD3_k127_6265931_9 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 494.0
HFD3_k127_6272657_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 2.92e-262 836.0
HFD3_k127_6272657_1 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001266 238.0
HFD3_k127_6272657_2 DDE superfamily endonuclease - - - 0.000000000000000000000000003091 120.0
HFD3_k127_6272657_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000166 52.0
HFD3_k127_6287962_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.018e-276 859.0
HFD3_k127_6287962_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 561.0
HFD3_k127_6287962_10 - - - - 0.00001178 51.0
HFD3_k127_6287962_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 472.0
HFD3_k127_6287962_3 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
HFD3_k127_6287962_4 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 384.0
HFD3_k127_6287962_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 370.0
HFD3_k127_6287962_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 353.0
HFD3_k127_6287962_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
HFD3_k127_6287962_8 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000009031 259.0
HFD3_k127_6287962_9 - - - - 0.00000000003459 68.0
HFD3_k127_6299252_0 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000006405 215.0
HFD3_k127_6299252_1 SCO1/SenC K07152 - - 0.0000000000000000000000000000000002351 140.0
HFD3_k127_6299252_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000002755 115.0
HFD3_k127_6299252_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001377 61.0
HFD3_k127_6299252_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000165 59.0
HFD3_k127_6313041_0 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 328.0
HFD3_k127_6313041_1 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 325.0
HFD3_k127_6313041_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000001116 137.0
HFD3_k127_6313041_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000001611 136.0
HFD3_k127_6315554_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1512.0
HFD3_k127_6315554_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.583e-205 666.0
HFD3_k127_6315554_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 536.0
HFD3_k127_6315554_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003616 293.0
HFD3_k127_6315554_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
HFD3_k127_6315554_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003943 273.0
HFD3_k127_6315554_6 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.00000000000000000000000000000000000000000000000000005718 192.0
HFD3_k127_6315554_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000003738 167.0
HFD3_k127_6326656_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 594.0
HFD3_k127_6326656_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 569.0
HFD3_k127_6326656_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 364.0
HFD3_k127_6326656_3 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000004072 110.0
HFD3_k127_6326656_4 - - - - 0.0000000000000351 79.0
HFD3_k127_6354519_0 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 435.0
HFD3_k127_6354519_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 343.0
HFD3_k127_6354519_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 319.0
HFD3_k127_6354519_3 cellulose binding - - - 0.000000000000000000000000000000000000000000000000003961 187.0
HFD3_k127_6354519_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000003593 172.0
HFD3_k127_6354519_5 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000007695 151.0
HFD3_k127_6354519_6 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000004721 118.0
HFD3_k127_6354519_7 Alpha beta hydrolase - - - 0.0000000000000000000000003648 116.0
HFD3_k127_6354519_8 energy transducer activity K03832 - - 0.000001205 60.0
HFD3_k127_6358582_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 390.0
HFD3_k127_6358582_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 324.0
HFD3_k127_6358582_2 PFAM ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 291.0
HFD3_k127_6358582_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000007568 213.0
HFD3_k127_6358582_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000001014 204.0
HFD3_k127_6358582_5 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000002217 173.0
HFD3_k127_6358582_6 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000013 142.0
HFD3_k127_6358582_7 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000006563 146.0
HFD3_k127_6358582_8 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000004798 109.0
HFD3_k127_6358582_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000001397 64.0
HFD3_k127_6384574_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 301.0
HFD3_k127_6384574_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002288 230.0
HFD3_k127_6384574_3 chaperone-mediated protein complex assembly - - - 0.000000000000000000009067 98.0
HFD3_k127_6384574_4 chaperone-mediated protein complex assembly - - - 0.000003635 58.0
HFD3_k127_6392622_0 PFAM PrkA AAA K07180 - - 0.0 1020.0
HFD3_k127_6392622_1 SpoVR family K06415 - - 1.587e-195 621.0
HFD3_k127_6392622_2 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 532.0
HFD3_k127_6392622_3 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 511.0
HFD3_k127_6392622_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 460.0
HFD3_k127_6392622_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 265.0
HFD3_k127_6392622_6 Histidine kinase - - - 0.000000000000000000000000000000000000000008 177.0
HFD3_k127_6392622_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000002779 149.0
HFD3_k127_6392622_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000009182 101.0
HFD3_k127_6414840_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 0.0 1022.0
HFD3_k127_6414840_1 Homospermidine synthase K00808 - 2.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 591.0
HFD3_k127_6414840_2 Protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000637 101.0
HFD3_k127_6414840_3 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000005009 87.0
HFD3_k127_6414840_4 AsmA-like C-terminal region K07289 - - 0.0001106 55.0
HFD3_k127_6416175_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 528.0
HFD3_k127_6416175_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 501.0
HFD3_k127_6416175_10 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000006793 269.0
HFD3_k127_6416175_11 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000007684 243.0
HFD3_k127_6416175_12 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000005626 212.0
HFD3_k127_6416175_13 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000003089 207.0
HFD3_k127_6416175_14 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000007138 190.0
HFD3_k127_6416175_15 GAF domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000003147 163.0
HFD3_k127_6416175_16 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000004967 145.0
HFD3_k127_6416175_17 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000001151 104.0
HFD3_k127_6416175_18 NMT1-like family K02051 - - 0.0000000000000000000001295 110.0
HFD3_k127_6416175_19 Response regulator receiver domain - - - 0.000000000001954 72.0
HFD3_k127_6416175_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 452.0
HFD3_k127_6416175_20 YfdX protein - - - 0.0000000002168 69.0
HFD3_k127_6416175_21 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000002889 53.0
HFD3_k127_6416175_22 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0002009 46.0
HFD3_k127_6416175_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 447.0
HFD3_k127_6416175_4 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 409.0
HFD3_k127_6416175_5 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 362.0
HFD3_k127_6416175_6 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 338.0
HFD3_k127_6416175_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 335.0
HFD3_k127_6416175_8 COGs COG0616 Periplasmic serine protease (ClpP class) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
HFD3_k127_6416175_9 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 289.0
HFD3_k127_6418671_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 437.0
HFD3_k127_6418671_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000005802 235.0
HFD3_k127_6418671_2 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000005128 126.0
HFD3_k127_6418671_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000003337 112.0
HFD3_k127_6418671_4 Integrase core domain - - - 0.00000023 55.0
HFD3_k127_6432410_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
HFD3_k127_6432410_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002781 284.0
HFD3_k127_6432410_2 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000007091 201.0
HFD3_k127_6432410_3 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000001453 164.0
HFD3_k127_6432410_4 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000009415 85.0
HFD3_k127_6440652_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1291.0
HFD3_k127_6440652_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 535.0
HFD3_k127_6440652_10 Glycine zipper - - - 0.000008166 53.0
HFD3_k127_6440652_11 Putative peptidoglycan binding domain - - - 0.0001288 50.0
HFD3_k127_6440652_12 Carbohydrate-selective porin K07267 - - 0.0009181 45.0
HFD3_k127_6440652_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 347.0
HFD3_k127_6440652_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 310.0
HFD3_k127_6440652_4 - - - - 0.000000000000000000000000000004307 124.0
HFD3_k127_6440652_5 SpoIIAA-like - - - 0.0000000000000000001443 93.0
HFD3_k127_6440652_6 - - - - 0.0000000000000008479 84.0
HFD3_k127_6440652_7 - - - - 0.0000000000005727 72.0
HFD3_k127_6440652_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.000000000003181 67.0
HFD3_k127_6440652_9 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 0.0000002742 57.0
HFD3_k127_6442577_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 311.0
HFD3_k127_6442577_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000008669 194.0
HFD3_k127_6442577_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000006409 183.0
HFD3_k127_6442577_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000005643 166.0
HFD3_k127_6442577_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000002472 138.0
HFD3_k127_6448364_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 1.794e-258 822.0
HFD3_k127_6448364_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
HFD3_k127_6448364_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000001585 199.0
HFD3_k127_6448364_3 - K07275 - - 0.000000000000000000000000000000001911 137.0
HFD3_k127_6448364_4 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000003543 85.0
HFD3_k127_6448364_5 response to toxic substance K16347,K16348 - - 0.000005885 53.0
HFD3_k127_6473066_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1023.0
HFD3_k127_6473066_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1009.0
HFD3_k127_6473066_10 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000009603 209.0
HFD3_k127_6473066_11 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000002759 163.0
HFD3_k127_6473066_12 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000001072 124.0
HFD3_k127_6473066_2 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 4.197e-227 713.0
HFD3_k127_6473066_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 519.0
HFD3_k127_6473066_4 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 460.0
HFD3_k127_6473066_5 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 382.0
HFD3_k127_6473066_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 316.0
HFD3_k127_6473066_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 296.0
HFD3_k127_6473066_8 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 275.0
HFD3_k127_6473066_9 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000003248 248.0
HFD3_k127_6485875_0 Domain of Unknown Function (DUF748) - - - 1.09e-204 673.0
HFD3_k127_6485875_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004699 266.0
HFD3_k127_6485875_2 - - - - 0.000000000000000000000000000000000000000000000005912 185.0
HFD3_k127_6485875_3 - - - - 0.0000000000000000000002443 98.0
HFD3_k127_6485875_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000009145 76.0
HFD3_k127_6495301_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 379.0
HFD3_k127_6495301_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 365.0
HFD3_k127_6495301_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000005043 243.0
HFD3_k127_6495301_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000007424 231.0
HFD3_k127_6495301_4 ribonucleoside-diphosphate reductase activity K07735 - - 0.0000000000000000000000000000000000000000000000000002187 199.0
HFD3_k127_6495301_5 Peptidase S16, lon domain protein K07157 - - 0.0000000000000000000000000000000000000000001426 167.0
HFD3_k127_6495301_6 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000001035 152.0
HFD3_k127_6495301_7 Sigma-70, region 4 K03088 - - 0.00000000000000000000005389 100.0
HFD3_k127_6495301_8 Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000000001055 92.0
HFD3_k127_6495301_9 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000002102 81.0
HFD3_k127_6515452_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 444.0
HFD3_k127_6515452_1 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 336.0
HFD3_k127_6515452_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 288.0
HFD3_k127_6515452_3 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000005642 164.0
HFD3_k127_6515452_4 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000002013 149.0
HFD3_k127_6515452_5 cytochrome - - - 0.0000000000000000000000001106 112.0
HFD3_k127_6515452_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000001545 94.0
HFD3_k127_6515452_7 GYD domain - - - 0.00007181 52.0
HFD3_k127_6527343_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 566.0
HFD3_k127_6527343_1 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 519.0
HFD3_k127_6527343_10 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000335 247.0
HFD3_k127_6527343_11 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000003321 248.0
HFD3_k127_6527343_12 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000004671 242.0
HFD3_k127_6527343_13 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.0000000000000000000000000000000000000000000000000000000004709 213.0
HFD3_k127_6527343_14 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000008603 181.0
HFD3_k127_6527343_15 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000003272 170.0
HFD3_k127_6527343_16 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000002777 147.0
HFD3_k127_6527343_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000001757 146.0
HFD3_k127_6527343_18 Amidohydrolase K07045 - - 0.0000000000000000000000000000000002022 143.0
HFD3_k127_6527343_19 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000001715 123.0
HFD3_k127_6527343_2 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 421.0
HFD3_k127_6527343_20 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000009368 107.0
HFD3_k127_6527343_21 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000002529 94.0
HFD3_k127_6527343_22 Cupin - - - 0.00000000000006993 79.0
HFD3_k127_6527343_23 Rhodanese Homology Domain - - - 0.000000002439 61.0
HFD3_k127_6527343_24 TIM-barrel fold metal-dependent hydrolase - - - 0.000004765 50.0
HFD3_k127_6527343_3 LVIVD repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 410.0
HFD3_k127_6527343_4 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 378.0
HFD3_k127_6527343_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 347.0
HFD3_k127_6527343_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 366.0
HFD3_k127_6527343_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 310.0
HFD3_k127_6527343_8 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
HFD3_k127_6527343_9 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001524 273.0
HFD3_k127_6553776_0 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 595.0
HFD3_k127_6553776_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 528.0
HFD3_k127_6553776_2 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 427.0
HFD3_k127_6553776_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 293.0
HFD3_k127_6553776_4 PFAM O-Antigen ligase - - - 0.000000000000000000000000001558 121.0
HFD3_k127_6553776_5 Flavin containing amine oxidoreductase - - - 0.0000004941 56.0
HFD3_k127_6576334_0 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
HFD3_k127_6576334_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 415.0
HFD3_k127_6576334_10 Transcriptional regulator PadR-like family - - - 0.000000000000000000000001941 106.0
HFD3_k127_6576334_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000004048 67.0
HFD3_k127_6576334_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 378.0
HFD3_k127_6576334_3 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 371.0
HFD3_k127_6576334_4 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 339.0
HFD3_k127_6576334_5 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001029 235.0
HFD3_k127_6576334_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000006871 181.0
HFD3_k127_6576334_7 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000001712 179.0
HFD3_k127_6576334_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000003728 156.0
HFD3_k127_6576334_9 PFAM molybdopterin binding - - - 0.000000000000000000000000005198 111.0
HFD3_k127_6607183_0 MmgE/PrpD family - - - 1.608e-194 618.0
HFD3_k127_6607183_1 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 475.0
HFD3_k127_6607183_2 HIT domain - - - 0.00000000000000000000000000000000000000000007012 169.0
HFD3_k127_6607183_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000007687 154.0
HFD3_k127_6607183_4 CoA-transferase family III K18289 - 2.8.3.22 0.0000000489 56.0
HFD3_k127_6607183_5 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000005258 52.0
HFD3_k127_6607183_6 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.00004407 50.0
HFD3_k127_6622366_0 TIGRFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 382.0
HFD3_k127_6622366_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000372 286.0
HFD3_k127_6622366_2 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001434 269.0
HFD3_k127_6622366_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002151 250.0
HFD3_k127_6622366_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000002579 216.0
HFD3_k127_6622366_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000005398 196.0
HFD3_k127_6622366_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000001553 149.0
HFD3_k127_6622366_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000004796 90.0
HFD3_k127_6622366_8 phosphonopyruvate decarboxylase K09459 - 4.1.1.82 0.00000000009075 69.0
HFD3_k127_6639249_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1039.0
HFD3_k127_6639249_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 8.393e-275 861.0
HFD3_k127_6639249_2 Cysteine-rich domain - - - 1.959e-199 626.0
HFD3_k127_6639249_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
HFD3_k127_6647241_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 376.0
HFD3_k127_6647241_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001185 282.0
HFD3_k127_6647241_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000716 96.0
HFD3_k127_6647241_3 PKD domain containing protein - - - 0.00000000000000007503 94.0
HFD3_k127_6647241_4 Domain of unknown function (DUF4258) - - - 0.000000000000000832 80.0
HFD3_k127_6647241_5 - - - - 0.000000002118 62.0
HFD3_k127_6647241_6 Serine aminopeptidase, S33 K06889 - - 0.000006086 52.0
HFD3_k127_6662781_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 385.0
HFD3_k127_6662781_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002801 282.0
HFD3_k127_6662781_2 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002782 267.0
HFD3_k127_6662781_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000001022 174.0
HFD3_k127_6662781_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000004848 99.0
HFD3_k127_6662781_5 Dimerisation domain - - - 0.0000000000000000002666 90.0
HFD3_k127_6692609_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 484.0
HFD3_k127_6692609_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 369.0
HFD3_k127_6692609_2 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 297.0
HFD3_k127_6692609_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000001323 209.0
HFD3_k127_6692609_4 TPM domain K06872 - - 0.0000000007279 67.0
HFD3_k127_6692609_5 COG0477 Permeases of the major facilitator superfamily K08151 - - 0.000009836 57.0
HFD3_k127_6692609_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00002703 46.0
HFD3_k127_6732829_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 437.0
HFD3_k127_6732829_1 FMN-dependent dehydrogenase K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 364.0
HFD3_k127_6732829_10 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000117 104.0
HFD3_k127_6732829_11 Glyoxalase-like domain - - - 0.00000000000000000000002277 104.0
HFD3_k127_6732829_12 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000000003047 92.0
HFD3_k127_6732829_13 - - - - 0.00000000000166 74.0
HFD3_k127_6732829_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 347.0
HFD3_k127_6732829_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 311.0
HFD3_k127_6732829_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000006143 252.0
HFD3_k127_6732829_5 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000007461 203.0
HFD3_k127_6732829_6 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000005205 175.0
HFD3_k127_6732829_7 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.0000000000000000000000000000000000000003019 154.0
HFD3_k127_6732829_8 molybdopterin cofactor binding K07402 - - 0.000000000000000000000000000001674 125.0
HFD3_k127_6732829_9 Alpha beta - - - 0.00000000000000000000000000001268 129.0
HFD3_k127_6733354_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 2.595e-198 628.0
HFD3_k127_6733354_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 449.0
HFD3_k127_6733354_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
HFD3_k127_6733354_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000006907 183.0
HFD3_k127_6733354_4 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000001141 133.0
HFD3_k127_6733354_5 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000001919 109.0
HFD3_k127_6733354_6 Chromate transporter K07240 - - 0.0000000000000002133 87.0
HFD3_k127_6733354_7 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00001016 52.0
HFD3_k127_6782848_0 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 5.888e-241 757.0
HFD3_k127_6782848_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000002342 119.0
HFD3_k127_6782848_2 Pfam Amidohydrolase - - - 0.000000000000000000000002197 108.0
HFD3_k127_6782848_3 NMT1-like family K02051 - - 0.0000000000001529 81.0
HFD3_k127_6791300_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
HFD3_k127_6791300_1 tRNA methyltransferase complex GCD14 subunit N-term K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
HFD3_k127_6791300_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
HFD3_k127_6791300_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000001183 195.0
HFD3_k127_6791300_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000007621 197.0
HFD3_k127_6791300_5 PFAM Chlorite dismutase - - - 0.0000000000000000000000000000000000004408 141.0
HFD3_k127_6791300_6 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000005625 136.0
HFD3_k127_6791300_7 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000000005389 94.0
HFD3_k127_679143_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.818e-311 964.0
HFD3_k127_679143_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 1.064e-277 860.0
HFD3_k127_679143_2 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 9.703e-232 733.0
HFD3_k127_679143_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 544.0
HFD3_k127_679143_4 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 340.0
HFD3_k127_679143_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 299.0
HFD3_k127_679143_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001564 306.0
HFD3_k127_679143_7 COG3668 Plasmid stabilization system protein - - - 0.00000000000000000000000000000006966 128.0
HFD3_k127_679143_8 response regulator K02490 - - 0.000000000000000002757 89.0
HFD3_k127_679143_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000001868 78.0
HFD3_k127_6791843_0 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 622.0
HFD3_k127_6791843_1 Sigma-54 interaction domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 407.0
HFD3_k127_6791843_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 355.0
HFD3_k127_6791843_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000004145 211.0
HFD3_k127_6791843_4 Protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000001336 109.0
HFD3_k127_6791843_5 peptidyl-tyrosine sulfation - - - 0.00000000000000006824 92.0
HFD3_k127_6810664_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 590.0
HFD3_k127_6810664_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 415.0
HFD3_k127_6810664_2 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009459 284.0
HFD3_k127_6810664_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000009879 94.0
HFD3_k127_6810664_4 gag-polyprotein putative aspartyl protease K06985 - - 0.0000004275 60.0
HFD3_k127_6810664_5 Sporulation related domain K03749 - - 0.0002175 53.0
HFD3_k127_6819072_0 PFAM sigma-54 factor interaction domain-containing protein K00575,K12266 - 2.1.1.80 8.408e-212 693.0
HFD3_k127_6819072_1 Carbon-nitrogen hydrolase K01502 - 3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 571.0
HFD3_k127_6819072_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001983 301.0
HFD3_k127_6819072_4 Domain of unknown function DUF302 - - - 0.0000000000000007831 81.0
HFD3_k127_6819072_5 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000002615 54.0
HFD3_k127_6843514_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 484.0
HFD3_k127_6843514_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 461.0
HFD3_k127_6843514_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 380.0
HFD3_k127_6843514_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 342.0
HFD3_k127_6843514_4 BON domain - - - 0.0000000000000000007023 90.0
HFD3_k127_6891688_0 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000001318 216.0
HFD3_k127_6891688_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.0000000000000000000000000000000000000000000000000000006001 209.0
HFD3_k127_6891688_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000239 161.0
HFD3_k127_6891688_3 Predicted permease K07089 - - 0.000000000000000000000000000000004067 136.0
HFD3_k127_6891688_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.00000000000000000007125 91.0
HFD3_k127_6891688_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000001287 59.0
HFD3_k127_6912238_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.283e-206 657.0
HFD3_k127_6912238_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
HFD3_k127_6912238_2 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 259.0
HFD3_k127_6912782_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 4.861e-209 666.0
HFD3_k127_6912782_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000003719 141.0
HFD3_k127_6912782_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000004047 100.0
HFD3_k127_6994855_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 607.0
HFD3_k127_6994855_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 497.0
HFD3_k127_6994855_10 - - - - 0.0005555 44.0
HFD3_k127_6994855_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 478.0
HFD3_k127_6994855_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 443.0
HFD3_k127_6994855_4 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 443.0
HFD3_k127_6994855_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000006245 239.0
HFD3_k127_6994855_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000001101 186.0
HFD3_k127_6994855_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000004458 116.0
HFD3_k127_6994855_8 Glycine-zipper domain - - - 0.00000000019 62.0
HFD3_k127_6994855_9 Fic/DOC family K04095 - - 0.00000001899 57.0
HFD3_k127_6999204_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.214e-198 640.0
HFD3_k127_6999204_1 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 462.0
HFD3_k127_6999204_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000001195 112.0
HFD3_k127_6999204_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000009214 92.0
HFD3_k127_7002297_0 NAD(P)-binding Rossmann-like domain - - - 6.089e-199 637.0
HFD3_k127_7002297_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 531.0
HFD3_k127_7002297_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 270.0
HFD3_k127_7002297_11 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
HFD3_k127_7002297_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000172 253.0
HFD3_k127_7002297_13 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000004584 233.0
HFD3_k127_7002297_14 Alpha/beta hydrolase family K10216 - 3.7.1.9 0.0000000000000000000000000000000000000000000000000000000000002556 221.0
HFD3_k127_7002297_15 COG0006 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000006199 223.0
HFD3_k127_7002297_16 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000001517 213.0
HFD3_k127_7002297_17 Protein of unknown function (DUF2971) - - - 0.000000000000000000000000000000000000000000000000000000001551 211.0
HFD3_k127_7002297_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000002773 204.0
HFD3_k127_7002297_19 membrane K02050 - - 0.00000000000000000000000000000000000000000006014 171.0
HFD3_k127_7002297_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 436.0
HFD3_k127_7002297_20 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000006128 165.0
HFD3_k127_7002297_21 NMT1-like family K02051 - - 0.00000000000000000000000000000000000001139 157.0
HFD3_k127_7002297_22 Ndr family K01055 - 3.1.1.24 0.000000000000000000000000147 117.0
HFD3_k127_7002297_23 NMT1-like family - - - 0.0000000000000000006633 100.0
HFD3_k127_7002297_24 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00001985 56.0
HFD3_k127_7002297_25 Glyoxalase-like domain K08234 - - 0.00008979 50.0
HFD3_k127_7002297_3 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 356.0
HFD3_k127_7002297_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HFD3_k127_7002297_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 319.0
HFD3_k127_7002297_6 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 337.0
HFD3_k127_7002297_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 284.0
HFD3_k127_7002297_8 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006746 276.0
HFD3_k127_7002297_9 ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000144 273.0
HFD3_k127_7009670_0 Glycogen debranching enzyme - - - 0.0 1658.0
HFD3_k127_7009670_1 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1036.0
HFD3_k127_7009670_10 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 427.0
HFD3_k127_7009670_11 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 331.0
HFD3_k127_7009670_12 hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 312.0
HFD3_k127_7009670_13 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 286.0
HFD3_k127_7009670_14 Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003799 256.0
HFD3_k127_7009670_15 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000005122 237.0
HFD3_k127_7009670_16 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000005465 203.0
HFD3_k127_7009670_17 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000001633 198.0
HFD3_k127_7009670_18 Serine aminopeptidase, S33 K18100 - - 0.000000000000000000000000000000000000000000000000000009128 199.0
HFD3_k127_7009670_19 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000834 162.0
HFD3_k127_7009670_2 Phosphoglucose isomerase K01810 - 5.3.1.9 5.341e-295 911.0
HFD3_k127_7009670_20 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000008776 132.0
HFD3_k127_7009670_21 - - - - 0.000000000000000000000000000001009 126.0
HFD3_k127_7009670_22 NMT1-like family K07080 - - 0.0000000000000000000000000009738 124.0
HFD3_k127_7009670_24 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000000001438 107.0
HFD3_k127_7009670_25 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000002342 106.0
HFD3_k127_7009670_26 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000002044 98.0
HFD3_k127_7009670_27 ROK family K00886 - 2.7.1.63 0.000000000000000000007484 94.0
HFD3_k127_7009670_28 - - - - 0.00000000000000000005384 103.0
HFD3_k127_7009670_29 ATPase (AAA superfamily - - - 0.0000007588 51.0
HFD3_k127_7009670_3 Glycogen debranching enzyme - - - 1.229e-257 803.0
HFD3_k127_7009670_30 Alpha amylase, catalytic domain - - - 0.00002389 53.0
HFD3_k127_7009670_32 Alpha/beta hydrolase family - - - 0.0002915 49.0
HFD3_k127_7009670_33 alpha amylase, catalytic region - - - 0.0008741 42.0
HFD3_k127_7009670_4 Alpha amylase, catalytic domain - - - 2.154e-243 759.0
HFD3_k127_7009670_5 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 6.434e-215 678.0
HFD3_k127_7009670_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 537.0
HFD3_k127_7009670_7 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 526.0
HFD3_k127_7009670_8 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 533.0
HFD3_k127_7009670_9 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 507.0
HFD3_k127_7012305_0 Pfam SNARE associated Golgi protein - - - 3.479e-217 694.0
HFD3_k127_7012305_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 367.0
HFD3_k127_7012305_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000003988 180.0
HFD3_k127_7012305_11 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000002952 81.0
HFD3_k127_7012305_12 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 - 4.1.1.98 0.00000000009947 63.0
HFD3_k127_7012305_2 PFAM ABC transporter related K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 310.0
HFD3_k127_7012305_3 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002071 266.0
HFD3_k127_7012305_4 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002509 250.0
HFD3_k127_7012305_5 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000002253 224.0
HFD3_k127_7012305_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000281 190.0
HFD3_k127_7012305_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000001247 189.0
HFD3_k127_7012305_8 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000000002396 198.0
HFD3_k127_7012305_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000001437 181.0
HFD3_k127_701851_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1197.0
HFD3_k127_701851_1 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 560.0
HFD3_k127_701851_10 PFAM methyltransferase K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000004195 214.0
HFD3_k127_701851_11 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000002146 229.0
HFD3_k127_701851_12 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000000001055 199.0
HFD3_k127_701851_13 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000001591 192.0
HFD3_k127_701851_14 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000003132 165.0
HFD3_k127_701851_15 Protein of unknown function (DUF721) - - - 0.000000000000000002416 93.0
HFD3_k127_701851_17 Tetratricopeptide repeat - - - 0.000000003481 67.0
HFD3_k127_701851_18 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00003049 54.0
HFD3_k127_701851_2 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
HFD3_k127_701851_3 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
HFD3_k127_701851_4 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 421.0
HFD3_k127_701851_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 312.0
HFD3_k127_701851_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
HFD3_k127_701851_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 305.0
HFD3_k127_701851_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
HFD3_k127_701851_9 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001849 233.0
HFD3_k127_7025073_0 Molybdopterin oxidoreductase - - - 0.0 1654.0
HFD3_k127_7025073_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 610.0
HFD3_k127_7025073_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 319.0
HFD3_k127_7025073_3 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000001225 175.0
HFD3_k127_7025073_4 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000002966 154.0
HFD3_k127_7025073_5 Nitrate reductase delta subunit - - - 0.000000000000000000000000001925 121.0
HFD3_k127_7025073_6 - - - - 0.0000000000000000000000003922 117.0
HFD3_k127_7025073_7 Transcriptional regulator - - - 0.00000000000008366 75.0
HFD3_k127_7032898_0 Response regulator, receiver K07677,K07679,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 528.0
HFD3_k127_7032898_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 356.0
HFD3_k127_7032898_10 ABC transporter substrate-binding protein K02012 - - 0.00001114 53.0
HFD3_k127_7032898_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000001195 235.0
HFD3_k127_7032898_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000004452 220.0
HFD3_k127_7032898_4 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000000003577 174.0
HFD3_k127_7032898_5 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000006182 162.0
HFD3_k127_7032898_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000004982 93.0
HFD3_k127_7032898_8 Conserved carboxylase domain - - - 0.000000000000008303 78.0
HFD3_k127_7032898_9 Transposase IS200 like - - - 0.000005945 49.0
HFD3_k127_7043105_0 Protein of unknown function, DUF255 K06888 - - 5.32e-225 718.0
HFD3_k127_7043105_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 319.0
HFD3_k127_7043105_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000001814 245.0
HFD3_k127_7043105_3 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000003777 231.0
HFD3_k127_7043105_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000002377 198.0
HFD3_k127_7043105_5 NMT1-like family - - - 0.00000000000000000000000001136 122.0
HFD3_k127_7043105_6 PIN domain - - - 0.0000000000000000000008906 100.0
HFD3_k127_7043105_7 Class II Aldolase and Adducin N-terminal domain K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.000000000000000156 88.0
HFD3_k127_7043105_8 Ribonuclease B OB domain K03704 - - 0.0000000006756 61.0
HFD3_k127_7044730_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001765 286.0
HFD3_k127_7044730_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000001667 130.0
HFD3_k127_7044730_2 Protein of unknown function (DUF1328) - - - 0.0000000000000009243 79.0
HFD3_k127_7044730_3 Domain of Unknown Function (DUF748) - - - 0.00000000000007745 74.0
HFD3_k127_7044730_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000005273 68.0
HFD3_k127_7044730_5 Protein of unknown function (DUF3096) - - - 0.00000000115 60.0
HFD3_k127_7050487_0 membrane carboxypeptidase (Penicillin-binding protein) - - - 1.914e-199 655.0
HFD3_k127_7050487_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 341.0
HFD3_k127_7050487_2 Amidohydrolase K07045 - - 0.000000000000000000000000000001588 134.0
HFD3_k127_7050487_3 coenzyme F420-1:gamma-L-glutamate ligase activity K04719 - 1.13.11.79 0.000000000000000000000000001609 121.0
HFD3_k127_7050487_4 - - - - 0.000000000000000001156 90.0
HFD3_k127_7050487_5 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000001849 77.0
HFD3_k127_7050487_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000000001848 75.0
HFD3_k127_7050487_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000002448 68.0
HFD3_k127_7050487_8 NMT1-like family K15553 - - 0.00001186 57.0
HFD3_k127_706274_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 6.26e-245 775.0
HFD3_k127_706274_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 2.803e-214 686.0
HFD3_k127_706274_2 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 575.0
HFD3_k127_706274_3 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 549.0
HFD3_k127_7066019_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 370.0
HFD3_k127_7066019_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 304.0
HFD3_k127_7066019_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000001879 173.0
HFD3_k127_7066019_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000002804 139.0
HFD3_k127_7066019_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.000000000000000000000000000000005441 135.0
HFD3_k127_7066019_5 - - - - 0.00000000000000000000000000001211 122.0
HFD3_k127_7066019_6 Protein of unknown function (DUF2442) - - - 0.00000000000000000001154 95.0
HFD3_k127_7066019_7 amidase activity K01426 - 3.5.1.4 0.00000000004565 68.0
HFD3_k127_7066019_8 aspartate kinase activity - - - 0.00000000006143 70.0
HFD3_k127_7066019_9 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00003726 47.0
HFD3_k127_7071885_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.154e-268 844.0
HFD3_k127_7071885_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 524.0
HFD3_k127_7071885_10 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000005562 225.0
HFD3_k127_7071885_11 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000005211 206.0
HFD3_k127_7071885_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000002662 208.0
HFD3_k127_7071885_13 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000007133 195.0
HFD3_k127_7071885_14 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000002192 179.0
HFD3_k127_7071885_15 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.000000000000000000000000000000000000000000000002402 180.0
HFD3_k127_7071885_16 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.000000000000000000000000000000000000000000000006057 184.0
HFD3_k127_7071885_17 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000001625 173.0
HFD3_k127_7071885_18 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000009644 176.0
HFD3_k127_7071885_19 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000236 158.0
HFD3_k127_7071885_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
HFD3_k127_7071885_20 Methyltransferase domain - - - 0.0000000000000000000000000000000000001736 150.0
HFD3_k127_7071885_21 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000004151 144.0
HFD3_k127_7071885_22 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000001252 137.0
HFD3_k127_7071885_23 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000008475 131.0
HFD3_k127_7071885_24 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000007774 123.0
HFD3_k127_7071885_25 Glycosyl transferase family group 2 - - - 0.00000000000000000000000002054 120.0
HFD3_k127_7071885_26 kinase activity - - - 0.0000000000000000000000003597 116.0
HFD3_k127_7071885_27 - - - - 0.000000000000000000000000827 105.0
HFD3_k127_7071885_28 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000000171 103.0
HFD3_k127_7071885_29 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000004971 111.0
HFD3_k127_7071885_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 380.0
HFD3_k127_7071885_30 kinase activity - - - 0.00000000000000000003234 100.0
HFD3_k127_7071885_31 Methyltransferase domain - - - 0.0000000000000000004541 96.0
HFD3_k127_7071885_32 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000004582 85.0
HFD3_k127_7071885_34 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000004826 89.0
HFD3_k127_7071885_35 AsmA family K07289 - - 0.000000000005777 79.0
HFD3_k127_7071885_36 NMT1-like family K02051 - - 0.0000000001933 72.0
HFD3_k127_7071885_37 Transposase - - - 0.0001671 49.0
HFD3_k127_7071885_38 - - - - 0.0007966 51.0
HFD3_k127_7071885_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 368.0
HFD3_k127_7071885_5 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
HFD3_k127_7071885_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006905 274.0
HFD3_k127_7071885_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000007473 268.0
HFD3_k127_7071885_8 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000009641 255.0
HFD3_k127_7071885_9 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
HFD3_k127_7080470_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 313.0
HFD3_k127_7080470_1 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000001638 233.0
HFD3_k127_7080470_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000005618 180.0
HFD3_k127_7080470_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.0000001602 61.0
HFD3_k127_7102382_0 Belongs to the UbiD family K03182 - 4.1.1.98 2.548e-195 622.0
HFD3_k127_7102382_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 336.0
HFD3_k127_7102382_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 343.0
HFD3_k127_7102382_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 321.0
HFD3_k127_7102382_4 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000001168 76.0
HFD3_k127_7117749_0 Xanthine dehydrogenase K03520 - 1.2.5.3 4.506e-295 926.0
HFD3_k127_7117749_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 334.0
HFD3_k127_7117749_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 312.0
HFD3_k127_7117749_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000124 255.0
HFD3_k127_7117749_4 Belongs to the UbiD family K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000002936 241.0
HFD3_k127_7117749_5 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
HFD3_k127_7117749_6 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000003297 214.0
HFD3_k127_7117749_7 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000001107 164.0
HFD3_k127_7117749_8 Haem-degrading K11477 - - 0.000000000000001657 81.0
HFD3_k127_713405_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 427.0
HFD3_k127_713405_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 387.0
HFD3_k127_713405_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000008255 72.0
HFD3_k127_713405_3 Tetratricopeptide repeat - - - 0.00008185 48.0
HFD3_k127_7134985_0 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 382.0
HFD3_k127_7134985_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
HFD3_k127_7134985_2 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000002757 142.0
HFD3_k127_7134985_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000002472 123.0
HFD3_k127_7134985_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000003756 113.0
HFD3_k127_7134985_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000476 102.0
HFD3_k127_7134985_6 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.000000000000000000001035 106.0
HFD3_k127_7134985_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000175 94.0
HFD3_k127_7134985_8 NMT1-like family K02051,K15551 - - 0.00000437 58.0
HFD3_k127_7153310_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1338.0
HFD3_k127_7153310_1 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
HFD3_k127_7153310_2 Non-ribosomal peptide synthetase modules and related - - - 0.000000000000000000000000000000000000761 147.0
HFD3_k127_7153310_3 Thioesterase domain - - - 0.00000000000000000000000000008282 121.0
HFD3_k127_7153310_4 UDP binding domain K02474,K13015 - 1.1.1.136 0.00000002535 55.0
HFD3_k127_7153310_5 Carbamoyltransferase C-terminus K00612 - - 0.00003161 49.0
HFD3_k127_7161392_0 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
HFD3_k127_7161392_1 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000001609 211.0
HFD3_k127_7161392_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000009904 203.0
HFD3_k127_7161392_3 - - - - 0.00000000000000000000000001057 110.0
HFD3_k127_7161392_4 decarboxylase K01607 - 4.1.1.44 0.00000000000000001398 90.0
HFD3_k127_7161392_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000002125 89.0
HFD3_k127_7161392_6 Selenoprotein B glycine betaine sarcosine D-proline reductase - - - 0.000000002929 60.0
HFD3_k127_7161392_7 Alpha/beta hydrolase family - - - 0.00000189 50.0
HFD3_k127_7169584_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 2.229e-194 634.0
HFD3_k127_7169584_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000915 261.0
HFD3_k127_7169584_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001488 257.0
HFD3_k127_7169584_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000003601 206.0
HFD3_k127_7169584_4 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000002364 91.0
HFD3_k127_7169584_5 mttA/Hcf106 family K03116,K03117 - - 0.00000000000000001191 85.0
HFD3_k127_7169584_6 - - - - 0.0003215 45.0
HFD3_k127_71745_0 elongation factor Tu domain 2 protein K02355 - - 4.579e-239 758.0
HFD3_k127_71745_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 509.0
HFD3_k127_71745_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
HFD3_k127_71745_3 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 287.0
HFD3_k127_71745_4 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
HFD3_k127_71745_5 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000003638 188.0
HFD3_k127_71745_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000001441 148.0
HFD3_k127_71745_7 Amidohydrolase - - - 0.000000000000001709 88.0
HFD3_k127_71745_8 - - - - 0.0000000000002243 74.0
HFD3_k127_7176414_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1184.0
HFD3_k127_7176414_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 387.0
HFD3_k127_7176414_2 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HFD3_k127_7176414_3 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000007963 152.0
HFD3_k127_7176414_5 Elongator protein 3 MiaB NifB - - - 0.0002488 47.0
HFD3_k127_7194229_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 432.0
HFD3_k127_7194229_1 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 291.0
HFD3_k127_7194229_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008881 239.0
HFD3_k127_7194229_3 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000000000232 207.0
HFD3_k127_7194229_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000006948 166.0
HFD3_k127_7194229_5 MlaC protein - - - 0.000000000000000000000000000000000000006841 153.0
HFD3_k127_7194229_6 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000001879 113.0
HFD3_k127_7194229_7 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0009232 49.0
HFD3_k127_7200534_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 608.0
HFD3_k127_7200534_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 440.0
HFD3_k127_7200534_10 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000000000009262 182.0
HFD3_k127_7200534_11 Protein conserved in bacteria K18480 - - 0.0000000000000000000000000000000000000000000000002701 183.0
HFD3_k127_7200534_12 Amidohydrolase family K15358 - 3.5.2.18 0.000000000000000000000000000000000000000000000001328 178.0
HFD3_k127_7200534_13 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000008501 94.0
HFD3_k127_7200534_14 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000001476 57.0
HFD3_k127_7200534_15 - - - - 0.0000004409 57.0
HFD3_k127_7200534_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000004265 57.0
HFD3_k127_7200534_2 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 404.0
HFD3_k127_7200534_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
HFD3_k127_7200534_4 Luciferase-like monooxygenase K00320,K14728 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 326.0
HFD3_k127_7200534_5 Mammalian cell entry related domain protein K02067,K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 282.0
HFD3_k127_7200534_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
HFD3_k127_7200534_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000004022 222.0
HFD3_k127_7200534_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000001451 216.0
HFD3_k127_7200534_9 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000004192 198.0
HFD3_k127_7238660_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.209e-272 848.0
HFD3_k127_7238660_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 417.0
HFD3_k127_7238660_10 Universal bacterial protein YeaZ K14742 - - 0.000000000000000000000000000000000000000002206 164.0
HFD3_k127_7238660_11 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000001107 160.0
HFD3_k127_7238660_12 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000005789 127.0
HFD3_k127_7238660_13 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000003101 98.0
HFD3_k127_7238660_2 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
HFD3_k127_7238660_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 333.0
HFD3_k127_7238660_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003443 263.0
HFD3_k127_7238660_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002153 264.0
HFD3_k127_7238660_6 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003025 238.0
HFD3_k127_7238660_7 MlaD protein K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - 0.00000000000000000000000000000000000000000000000000000000000000005207 239.0
HFD3_k127_7238660_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000007241 212.0
HFD3_k127_7238660_9 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000003484 168.0
HFD3_k127_724796_0 mechanosensitive ion channel activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 574.0
HFD3_k127_724796_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 239.0
HFD3_k127_724796_2 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000000000000000000000000002037 162.0
HFD3_k127_724796_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000008299 137.0
HFD3_k127_724796_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000005628 122.0
HFD3_k127_724796_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000001332 122.0
HFD3_k127_724796_6 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K20448 - 1.17.1.5 0.00007233 49.0
HFD3_k127_724796_7 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0001651 44.0
HFD3_k127_7254490_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 5.097e-200 637.0
HFD3_k127_7254490_1 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 522.0
HFD3_k127_7254490_10 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000005891 163.0
HFD3_k127_7254490_11 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000003081 154.0
HFD3_k127_7254490_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000227 104.0
HFD3_k127_7254490_13 Rieske 2Fe-2S - - - 0.00000000000000000000003621 103.0
HFD3_k127_7254490_14 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000002057 94.0
HFD3_k127_7254490_15 Glutaredoxin K03676 - - 0.00000006699 59.0
HFD3_k127_7254490_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 344.0
HFD3_k127_7254490_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 311.0
HFD3_k127_7254490_4 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002973 254.0
HFD3_k127_7254490_5 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000549 251.0
HFD3_k127_7254490_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000001816 211.0
HFD3_k127_7254490_7 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HFD3_k127_7254490_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000004352 192.0
HFD3_k127_7254490_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000002818 176.0
HFD3_k127_7256939_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1198.0
HFD3_k127_7256939_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.142e-317 992.0
HFD3_k127_7256939_10 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 308.0
HFD3_k127_7256939_11 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003187 271.0
HFD3_k127_7256939_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000006339 248.0
HFD3_k127_7256939_13 PFAM Dihydrodipicolinate synthetase K11946,K11949 - 4.1.2.34 0.0000000000000000000000000000000000000000000000000000000003046 217.0
HFD3_k127_7256939_14 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000009084 204.0
HFD3_k127_7256939_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000005938 177.0
HFD3_k127_7256939_16 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000008598 167.0
HFD3_k127_7256939_17 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000001625 173.0
HFD3_k127_7256939_18 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000003266 141.0
HFD3_k127_7256939_19 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000002549 119.0
HFD3_k127_7256939_2 Heat shock 70 kDa protein K04043 - - 1.12e-303 941.0
HFD3_k127_7256939_20 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000001531 109.0
HFD3_k127_7256939_21 Prokaryotic N-terminal methylation motif - - - 0.0000000000001163 77.0
HFD3_k127_7256939_3 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 2.456e-208 662.0
HFD3_k127_7256939_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 551.0
HFD3_k127_7256939_5 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 491.0
HFD3_k127_7256939_6 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 464.0
HFD3_k127_7256939_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 384.0
HFD3_k127_7256939_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
HFD3_k127_7256939_9 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 341.0
HFD3_k127_7259106_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 423.0
HFD3_k127_7259106_1 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
HFD3_k127_7259106_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000002755 184.0
HFD3_k127_7289670_0 COG2303 Choline dehydrogenase and related flavoproteins K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 477.0
HFD3_k127_7289670_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 435.0
HFD3_k127_7289670_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000003176 149.0
HFD3_k127_7289670_11 NMT1-like family - - - 0.0000000000000000000000000000000000002336 153.0
HFD3_k127_7289670_12 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000003234 126.0
HFD3_k127_7289670_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000006654 128.0
HFD3_k127_7289670_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000003149 112.0
HFD3_k127_7289670_15 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000007892 108.0
HFD3_k127_7289670_16 Belongs to the BolA IbaG family - - - 0.00000000000000000000001433 102.0
HFD3_k127_7289670_17 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000005059 90.0
HFD3_k127_7289670_18 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000005197 82.0
HFD3_k127_7289670_19 - - - - 0.0000000000000009758 81.0
HFD3_k127_7289670_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
HFD3_k127_7289670_20 PAS fold - - - 0.000000000001498 79.0
HFD3_k127_7289670_21 PFAM Transposase DDE domain - - - 0.0000000004356 64.0
HFD3_k127_7289670_22 Methyltransferase domain - - - 0.00000002118 64.0
HFD3_k127_7289670_23 NMT1-like family - - - 0.00000008862 59.0
HFD3_k127_7289670_25 4,5-dihydroxyphthalate decarboxylase - - - 0.00004892 54.0
HFD3_k127_7289670_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.00009891 54.0
HFD3_k127_7289670_27 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.0003307 53.0
HFD3_k127_7289670_28 Redoxin - - - 0.0003359 49.0
HFD3_k127_7289670_29 Belongs to the 'phage' integrase family - - - 0.0006574 46.0
HFD3_k127_7289670_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 351.0
HFD3_k127_7289670_30 - - - - 0.0008132 49.0
HFD3_k127_7289670_4 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
HFD3_k127_7289670_5 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HFD3_k127_7289670_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.0000000000000000000000000000000000000000000000000000304 203.0
HFD3_k127_7289670_7 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.000000000000000000000000000000000000000000000001181 181.0
HFD3_k127_7289670_8 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000000000000000000000000000000007788 180.0
HFD3_k127_7289670_9 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000007329 154.0
HFD3_k127_7311561_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 387.0
HFD3_k127_7311561_1 FAH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002207 283.0
HFD3_k127_7311561_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000279 265.0
HFD3_k127_7311561_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
HFD3_k127_7311561_4 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000001361 208.0
HFD3_k127_7311561_5 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000001168 76.0
HFD3_k127_7324585_0 ABC transporter K06147,K18890 - - 3.469e-240 763.0
HFD3_k127_7324585_1 ABC transporter transmembrane region K06147,K18889 - - 1.106e-197 635.0
HFD3_k127_7324585_10 Fibronectin type 3 domain - - - 0.000005854 55.0
HFD3_k127_7324585_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 610.0
HFD3_k127_7324585_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 572.0
HFD3_k127_7324585_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 549.0
HFD3_k127_7324585_5 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 544.0
HFD3_k127_7324585_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 358.0
HFD3_k127_7324585_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 334.0
HFD3_k127_7324585_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 301.0
HFD3_k127_7324585_9 aminopeptidase N - - - 0.00000001923 65.0
HFD3_k127_7359184_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 468.0
HFD3_k127_7359184_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 328.0
HFD3_k127_7359184_2 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001244 239.0
HFD3_k127_7359184_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000006051 156.0
HFD3_k127_7359184_4 NMT1/THI5 like K02051 - - 0.0000126 57.0
HFD3_k127_7370815_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 476.0
HFD3_k127_7370815_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004558 277.0
HFD3_k127_7370815_10 - - - - 0.00000745 54.0
HFD3_k127_7370815_2 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000000000003583 206.0
HFD3_k127_7370815_3 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000002971 127.0
HFD3_k127_7370815_4 PFAM AIG2 family protein - - - 0.00000000000000000000000001744 114.0
HFD3_k127_7370815_5 NMT1-like family K02051 - - 0.00000000000000000000009569 107.0
HFD3_k127_7370815_6 NMT1-like family - - - 0.00000000000000000000997 106.0
HFD3_k127_7370815_7 sequence-specific DNA binding K07726 - - 0.000000000000001163 77.0
HFD3_k127_7370815_8 - - - - 0.00000001037 59.0
HFD3_k127_7370815_9 Protein of unknown function (DUF3309) - - - 0.00000001832 56.0
HFD3_k127_7386676_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 424.0
HFD3_k127_7386676_1 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 394.0
HFD3_k127_7386676_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001652 244.0
HFD3_k127_7386676_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000314 244.0
HFD3_k127_7386676_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 242.0
HFD3_k127_7386676_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000299 142.0
HFD3_k127_7386676_6 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000682 94.0
HFD3_k127_7386676_7 cheY-homologous receiver domain - - - 0.000000000000000004928 85.0
HFD3_k127_7440955_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.169e-210 668.0
HFD3_k127_7440955_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 506.0
HFD3_k127_7440955_10 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005089 261.0
HFD3_k127_7440955_11 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
HFD3_k127_7440955_12 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
HFD3_k127_7440955_13 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.000000000000000000000000000000000000000000000000000000001173 210.0
HFD3_k127_7440955_14 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000001783 207.0
HFD3_k127_7440955_15 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000003904 182.0
HFD3_k127_7440955_16 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000612 183.0
HFD3_k127_7440955_17 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000001847 160.0
HFD3_k127_7440955_18 NMT1-like family K02051 - - 0.00000000000000000000000000000009362 136.0
HFD3_k127_7440955_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000015 115.0
HFD3_k127_7440955_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 484.0
HFD3_k127_7440955_20 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000009816 119.0
HFD3_k127_7440955_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 484.0
HFD3_k127_7440955_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 458.0
HFD3_k127_7440955_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 395.0
HFD3_k127_7440955_6 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 389.0
HFD3_k127_7440955_7 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 379.0
HFD3_k127_7440955_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
HFD3_k127_7440955_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002609 265.0
HFD3_k127_7451302_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 556.0
HFD3_k127_7451302_1 Type II secretion system K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 348.0
HFD3_k127_7451302_10 Periplasmic or secreted lipoprotein - - - 0.0000000000000000001178 91.0
HFD3_k127_7451302_11 general secretion pathway protein K02457 - - 0.00000000000001044 83.0
HFD3_k127_7451302_12 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000307 76.0
HFD3_k127_7451302_13 pilus assembly protein PilW K02459 - - 0.00000000001515 74.0
HFD3_k127_7451302_14 General secretion pathway protein K02458 - - 0.0000000003357 66.0
HFD3_k127_7451302_15 General Secretion Pathway protein K02462 - - 0.0000938 52.0
HFD3_k127_7451302_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
HFD3_k127_7451302_3 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002715 264.0
HFD3_k127_7451302_4 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000008372 185.0
HFD3_k127_7451302_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000002494 177.0
HFD3_k127_7451302_6 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000007612 177.0
HFD3_k127_7451302_7 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000247 147.0
HFD3_k127_7451302_8 Fimbrial assembly protein (PilN) K02461 - - 0.000000000000000000000000000000007472 146.0
HFD3_k127_7453858_0 High confidence in function and specificity - - - 4.721e-281 878.0
HFD3_k127_7453858_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 3.019e-253 793.0
HFD3_k127_7453858_11 - - - - 0.0000009226 53.0
HFD3_k127_7453858_12 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0004362 43.0
HFD3_k127_7453858_2 Sucrose-6F-phosphate phosphohydrolase - - - 1.081e-198 634.0
HFD3_k127_7453858_3 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 405.0
HFD3_k127_7453858_4 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000001703 206.0
HFD3_k127_7453858_5 - - - - 0.00000000000000005251 85.0
HFD3_k127_7453858_6 UPF0391 membrane protein - - - 0.00000000000002414 75.0
HFD3_k127_7453858_7 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000003023 75.0
HFD3_k127_7453858_8 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000008461 70.0
HFD3_k127_7453858_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000001981 60.0
HFD3_k127_7459857_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 384.0
HFD3_k127_7459857_1 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 377.0
HFD3_k127_7459857_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
HFD3_k127_7459857_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000008646 123.0
HFD3_k127_7459857_4 Glycine-zipper domain - - - 0.000000000000000000000001218 108.0
HFD3_k127_7459857_5 Polymer-forming cytoskeletal - - - 0.00000000000000006401 85.0
HFD3_k127_7459857_6 Helix-turn-helix domain - - - 0.000000001123 62.0
HFD3_k127_7459857_8 ABC transporter substrate binding protein K01989 - - 0.00000000563 60.0
HFD3_k127_7459857_9 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00005007 50.0
HFD3_k127_7475362_0 High-affinity Fe2 Pb2 permease K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000101 242.0
HFD3_k127_7475362_1 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000002958 214.0
HFD3_k127_7475362_2 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.0000000000000000000000000000000000000000000000000008112 192.0
HFD3_k127_7475362_3 ABC transporter K02041 - 3.6.3.28 0.000000000000000000000000000000000000000002371 168.0
HFD3_k127_7475362_4 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000002823 162.0
HFD3_k127_7477540_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003692 259.0
HFD3_k127_7477540_1 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000000004719 238.0
HFD3_k127_7477540_2 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000002969 176.0
HFD3_k127_7477540_3 Histidine kinase - - - 0.0000000000000000000000000000000001014 154.0
HFD3_k127_7477540_4 response to oxidative stress K04063 - - 0.0002699 44.0
HFD3_k127_7497648_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 417.0
HFD3_k127_7497648_1 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 320.0
HFD3_k127_7497648_2 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001968 261.0
HFD3_k127_7497648_3 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000265 198.0
HFD3_k127_7497648_4 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000002579 184.0
HFD3_k127_7497648_5 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000002035 147.0
HFD3_k127_7497648_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000001045 131.0
HFD3_k127_7497648_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000003073 105.0
HFD3_k127_7517012_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 559.0
HFD3_k127_7517012_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 461.0
HFD3_k127_7517012_2 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
HFD3_k127_7517012_3 IPT/TIG domain - - - 0.00000000000000000000000000000000000000000000000000000000000004913 241.0
HFD3_k127_7517012_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000001057 186.0
HFD3_k127_7517012_5 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000006811 192.0
HFD3_k127_7517012_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000008267 177.0
HFD3_k127_7517012_7 MAPEG family - - - 0.00000000000000000000000000000000000000000005894 164.0
HFD3_k127_7517012_8 POTRA domain, FtsQ-type K03589 - - 0.00000000000000000000000000000006616 135.0
HFD3_k127_7517012_9 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000787 99.0
HFD3_k127_7517184_0 Glycosyl transferase, family 2 - - - 0.0 1091.0
HFD3_k127_7517184_1 PFAM ABC transporter, transmembrane region K06147,K11085 - - 1.193e-237 748.0
HFD3_k127_7517184_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 389.0
HFD3_k127_7517184_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004043 278.0
HFD3_k127_7517184_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000001242 218.0
HFD3_k127_7517184_5 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000008236 205.0
HFD3_k127_7517184_6 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000278 175.0
HFD3_k127_7517184_7 PFAM ABC transporter K02471 - - 0.00000000000000000000000000004852 119.0
HFD3_k127_7517184_8 4Fe-4S single cluster domain K05337 - - 0.00000000004698 65.0
HFD3_k127_7517184_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0007951 50.0
HFD3_k127_7519571_0 diguanylate cyclase K21020 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000006456 228.0
HFD3_k127_7519571_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000253 181.0
HFD3_k127_7519571_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000324 99.0
HFD3_k127_7519571_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000004639 91.0
HFD3_k127_7519571_4 EamA-like transporter family - - - 0.0000000003557 70.0
HFD3_k127_7519571_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000003749 65.0
HFD3_k127_7519571_6 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000009483 63.0
HFD3_k127_7519571_7 conserved protein, contains double-stranded beta-helix domain - - - 0.00003448 53.0
HFD3_k127_7519571_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00005458 49.0
HFD3_k127_754358_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 447.0
HFD3_k127_754358_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 334.0
HFD3_k127_754358_2 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 281.0
HFD3_k127_754358_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000001284 152.0
HFD3_k127_754358_4 - - - - 0.0000000000000000000000000000002449 125.0
HFD3_k127_754358_5 ABC transporter substrate binding protein K01989 - - 0.0000000000001147 75.0
HFD3_k127_754358_6 Hemerythrin HHE cation binding domain - - - 0.0000000000002967 76.0
HFD3_k127_754358_7 PFAM ABC transporter substrate binding protein K01989 - - 0.00000001686 64.0
HFD3_k127_754358_8 Helix-turn-helix domain - - - 0.0003485 46.0
HFD3_k127_7586142_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003506 265.0
HFD3_k127_7586142_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000005583 210.0
HFD3_k127_7586142_2 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000002972 177.0
HFD3_k127_7586142_3 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000653 165.0
HFD3_k127_7602021_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 411.0
HFD3_k127_7602021_1 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
HFD3_k127_7602021_2 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005672 276.0
HFD3_k127_7602021_3 Acyl-CoA synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000348 201.0
HFD3_k127_7602021_4 Phosphopantetheine attachment site - - - 0.000001277 56.0
HFD3_k127_7613416_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 436.0
HFD3_k127_7613416_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 364.0
HFD3_k127_7613416_2 STAS domain K06378 - - 0.000000000000000000000001101 108.0
HFD3_k127_7613416_3 anti-sigma regulatory factor, serine threonine protein kinase - - - 0.00000000000000000000001005 107.0
HFD3_k127_7615779_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 518.0
HFD3_k127_7615779_1 Multidrug ABC transporter ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 494.0
HFD3_k127_7615779_10 diguanylate cyclase - - - 0.000000000000000007068 96.0
HFD3_k127_7615779_11 F420H(2)-dependent quinone reductase - - - 0.00000000000004565 78.0
HFD3_k127_7615779_13 F420H(2)-dependent quinone reductase - - - 0.0001134 46.0
HFD3_k127_7615779_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 431.0
HFD3_k127_7615779_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 330.0
HFD3_k127_7615779_4 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
HFD3_k127_7615779_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
HFD3_k127_7615779_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000001392 207.0
HFD3_k127_7615779_7 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000001144 202.0
HFD3_k127_7615779_8 Haem-binding domain - - - 0.000000000000000000000000000000003941 132.0
HFD3_k127_7615779_9 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000003872 118.0
HFD3_k127_764939_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 425.0
HFD3_k127_764939_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
HFD3_k127_764939_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000003086 144.0
HFD3_k127_764939_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000005934 90.0
HFD3_k127_764939_4 - - - - 0.0000000000000001945 82.0
HFD3_k127_764939_5 - - - - 0.00000000000008681 78.0
HFD3_k127_7682547_0 Glycosyltransferase Family 4 - - - 2.925e-284 879.0
HFD3_k127_7682547_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.93e-217 680.0
HFD3_k127_7682547_2 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 531.0
HFD3_k127_7682547_3 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 496.0
HFD3_k127_7682547_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 436.0
HFD3_k127_7682547_5 cellular water homeostasis K03442,K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
HFD3_k127_7682547_6 RNA recognition motif - - - 0.000000000000000000000000000000000003847 139.0
HFD3_k127_7682547_7 - - - - 0.000000000000000000006974 96.0
HFD3_k127_7682547_8 DNA binding domain with preference for A/T rich regions - - - 0.00000000000000004198 87.0
HFD3_k127_7682547_9 Belongs to the methyltransferase superfamily K07444 - - 0.0002209 47.0
HFD3_k127_7747487_0 Asparaginase - - - 9.148e-202 643.0
HFD3_k127_7747487_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 606.0
HFD3_k127_7747487_10 - - - - 0.000001122 58.0
HFD3_k127_7747487_2 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 284.0
HFD3_k127_7747487_3 Pilus assembly protein PilX K02673 - - 0.00000000000000000000000002404 122.0
HFD3_k127_7747487_4 Pfam:N_methyl_2 - - - 0.00000000000000000000000008691 114.0
HFD3_k127_7747487_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 0.000000002856 58.0
HFD3_k127_7747487_7 type IV pilus modification protein PilV K02458,K02671 - - 0.00000001932 61.0
HFD3_k127_7747487_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000004774 55.0
HFD3_k127_7747487_9 COG4970 Tfp pilus assembly protein FimT K08085 - - 0.0000002005 59.0
HFD3_k127_7752250_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 1.115e-221 711.0
HFD3_k127_7752250_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 259.0
HFD3_k127_7752250_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001479 244.0
HFD3_k127_7752250_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000002181 238.0
HFD3_k127_7752250_4 ABC transporter substrate binding protein K01989 - - 0.00000000000006908 72.0
HFD3_k127_7752250_5 UDP-glucose 6-dehydrogenase K00012 GO:0003674,GO:0003824,GO:0003979,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006065,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030203,GO:0034641,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046398,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.22 0.00000000003941 67.0
HFD3_k127_7752250_6 - - - - 0.00000001601 61.0
HFD3_k127_780875_0 PGAP1-like protein - - - 1.519e-272 845.0
HFD3_k127_780875_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 548.0
HFD3_k127_780875_10 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000002717 188.0
HFD3_k127_780875_11 nuclease activity - - - 0.00000000000000000000000000000000000000000000001173 174.0
HFD3_k127_780875_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000004074 169.0
HFD3_k127_780875_13 PFAM Cache K08738 - - 0.00000000000000000000000000000006251 130.0
HFD3_k127_780875_14 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000004766 93.0
HFD3_k127_780875_15 helix_turn_helix, Lux Regulon - - - 0.00000000000000008315 80.0
HFD3_k127_780875_16 - - - - 0.00000000000003301 83.0
HFD3_k127_780875_18 Amidohydrolase - - - 0.00000000005502 68.0
HFD3_k127_780875_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 334.0
HFD3_k127_780875_20 Cupin domain - - - 0.00004314 50.0
HFD3_k127_780875_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
HFD3_k127_780875_4 PFAM CMP dCMP deaminase zinc-binding K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000002215 241.0
HFD3_k127_780875_5 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009738 239.0
HFD3_k127_780875_6 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000003703 238.0
HFD3_k127_780875_7 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000529 213.0
HFD3_k127_780875_8 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000000000000000005518 194.0
HFD3_k127_780875_9 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000002442 200.0
HFD3_k127_782564_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 321.0
HFD3_k127_782564_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 307.0
HFD3_k127_782564_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001777 198.0
HFD3_k127_782564_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000005626 54.0
HFD3_k127_790743_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 627.0
HFD3_k127_790743_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 367.0
HFD3_k127_790743_10 to Saccharomyces cerevisiae STI1 (YOR027W) K09553 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:1901363 - 0.000955 49.0
HFD3_k127_790743_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000003183 213.0
HFD3_k127_790743_3 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000005582 196.0
HFD3_k127_790743_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000002368 179.0
HFD3_k127_790743_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000008251 179.0
HFD3_k127_790743_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000002087 132.0
HFD3_k127_790743_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000002248 94.0
HFD3_k127_790743_8 PFAM Colicin V production protein K03558 - - 0.000000000000007458 81.0
HFD3_k127_790743_9 NMT1-like family K02051 - - 0.00000001727 66.0
HFD3_k127_791517_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 533.0
HFD3_k127_791517_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 421.0
HFD3_k127_791517_11 PKD domain containing protein K01179 - 3.2.1.4 0.0000000000005844 81.0
HFD3_k127_791517_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000115 79.0
HFD3_k127_791517_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 353.0
HFD3_k127_791517_3 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000001002 242.0
HFD3_k127_791517_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001249 227.0
HFD3_k127_791517_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
HFD3_k127_791517_6 COG0006 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000001447 213.0
HFD3_k127_791517_7 Transposase DDE domain - - - 0.0000000000000000000000000000000000000838 145.0
HFD3_k127_791517_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000009933 151.0
HFD3_k127_791517_9 MFS_1 like family - - - 0.0000000000000000000000000000001448 139.0
HFD3_k127_799753_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 566.0
HFD3_k127_799753_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 447.0
HFD3_k127_799753_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000002531 157.0
HFD3_k127_799753_11 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000002402 119.0
HFD3_k127_799753_12 - - - - 0.000000000000000000005507 97.0
HFD3_k127_799753_13 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000003331 93.0
HFD3_k127_799753_15 Phosphodiester glycosidase - - - 0.00001578 56.0
HFD3_k127_799753_16 F420H(2)-dependent quinone reductase - GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.00007976 50.0
HFD3_k127_799753_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 314.0
HFD3_k127_799753_3 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
HFD3_k127_799753_4 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
HFD3_k127_799753_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000008497 229.0
HFD3_k127_799753_6 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000009774 219.0
HFD3_k127_799753_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001971 199.0
HFD3_k127_799753_8 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000003701 186.0
HFD3_k127_799753_9 PFAM luciferase-like - - - 0.000000000000000000000000000000000000000000000003473 185.0
HFD3_k127_808672_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 506.0
HFD3_k127_808672_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 434.0
HFD3_k127_808672_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000224 266.0
HFD3_k127_808672_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000002948 191.0
HFD3_k127_808672_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000002057 128.0
HFD3_k127_808672_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000005473 120.0
HFD3_k127_808672_6 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000001096 118.0
HFD3_k127_808672_7 TIGRFAM YgiT-type zinc finger domain - - - 0.0000136 50.0
HFD3_k127_809535_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000293 211.0
HFD3_k127_809535_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000003505 126.0
HFD3_k127_809535_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000002093 102.0
HFD3_k127_809535_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000001742 62.0
HFD3_k127_809535_4 PAS fold K02482 - 2.7.13.3 0.0000005549 61.0
HFD3_k127_809535_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000003172 49.0
HFD3_k127_809535_6 Glycosyl transferases group 1 - - - 0.0004353 44.0
HFD3_k127_813289_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 573.0
HFD3_k127_813289_1 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 404.0
HFD3_k127_813289_2 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 413.0
HFD3_k127_813289_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000001044 196.0
HFD3_k127_813289_4 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000652 189.0
HFD3_k127_813289_5 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000002158 138.0
HFD3_k127_813289_6 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000001846 135.0
HFD3_k127_813289_7 2 iron, 2 sulfur cluster binding - - - 0.0000000000000003607 85.0
HFD3_k127_813289_8 ABC transporter substrate-binding protein K15551 - - 0.00000375 57.0
HFD3_k127_817359_0 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 297.0
HFD3_k127_817359_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000006611 182.0
HFD3_k127_817359_2 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000007019 173.0
HFD3_k127_817359_3 Sporulation related domain K03749 - - 0.00001977 55.0
HFD3_k127_817359_4 Transposase DDE domain - - - 0.0004793 45.0
HFD3_k127_817786_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 571.0
HFD3_k127_817786_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 378.0
HFD3_k127_817786_2 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 279.0
HFD3_k127_817786_3 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000007213 134.0
HFD3_k127_817786_4 NMT1-like family K02051 - - 0.000000000000000000000000001363 124.0
HFD3_k127_817786_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.000000000000000000005806 104.0
HFD3_k127_824002_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 400.0
HFD3_k127_824002_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 310.0
HFD3_k127_824002_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000009184 222.0
HFD3_k127_825221_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.676e-296 917.0
HFD3_k127_825221_1 Pfam SNARE associated Golgi protein - - - 4.488e-223 713.0
HFD3_k127_825221_10 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000001156 124.0
HFD3_k127_825221_11 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000008919 104.0
HFD3_k127_825221_12 Protein of unknown function (DUF3309) - - - 0.00000000000000000003274 90.0
HFD3_k127_825221_13 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03669 - - 0.0000000000000000001815 98.0
HFD3_k127_825221_15 Histidine kinase - - - 0.0000000001172 68.0
HFD3_k127_825221_16 Putative peptidoglycan binding domain - - - 0.000000003551 61.0
HFD3_k127_825221_17 SMART Rhodanese domain protein - - - 0.00001581 48.0
HFD3_k127_825221_18 Metallo-beta-lactamase superfamily - - - 0.0004026 45.0
HFD3_k127_825221_2 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 445.0
HFD3_k127_825221_3 protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 422.0
HFD3_k127_825221_4 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 388.0
HFD3_k127_825221_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 329.0
HFD3_k127_825221_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006131 267.0
HFD3_k127_825221_7 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000969 224.0
HFD3_k127_825221_8 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000008186 150.0
HFD3_k127_825221_9 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000004725 133.0
HFD3_k127_827059_0 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 5.947e-250 788.0
HFD3_k127_827059_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 516.0
HFD3_k127_827059_10 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000002287 57.0
HFD3_k127_827059_2 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 486.0
HFD3_k127_827059_3 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 390.0
HFD3_k127_827059_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
HFD3_k127_827059_5 Transglycosylase SLT domain K06381,K08309 - - 0.000000000000000000000000000000000000000000000000000001782 213.0
HFD3_k127_827059_6 Evidence 4 Homologs of previously reported genes of K07145,K21481 - 1.14.99.48,1.14.99.57 0.00000000000000000000000000000001721 129.0
HFD3_k127_827059_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000001779 94.0
HFD3_k127_827059_8 NMT1-like family K02051 - - 0.0000000000000000003896 99.0
HFD3_k127_827059_9 NMT1-like family K02051 - - 0.000000000000003552 87.0
HFD3_k127_831982_0 Substrate binding domain of ABC-type glycine betaine transport system K02051 - - 0.000000000000668 79.0
HFD3_k127_831982_1 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000000007271 76.0
HFD3_k127_831982_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.00001018 55.0
HFD3_k127_840343_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 340.0
HFD3_k127_840343_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
HFD3_k127_840343_2 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 268.0
HFD3_k127_840343_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000004213 245.0
HFD3_k127_840343_4 deacetylase K01452,K16842,K22278 - 3.5.1.104,3.5.1.41,3.5.2.5 0.00000000000000000000000000000000000001765 155.0
HFD3_k127_840343_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000002587 140.0
HFD3_k127_84213_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.554e-196 622.0
HFD3_k127_84213_1 elongator protein 3 miab nifb - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 537.0
HFD3_k127_84213_10 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000252 176.0
HFD3_k127_84213_11 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000113 144.0
HFD3_k127_84213_12 Belongs to the TPP enzyme family K13039 - 4.1.1.79 0.000000000000000000000000000000000007909 149.0
HFD3_k127_84213_13 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000003547 120.0
HFD3_k127_84213_14 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000006173 113.0
HFD3_k127_84213_15 NMT1-like family K02051 - - 0.000000000000000000001399 108.0
HFD3_k127_84213_16 - - - - 0.000000000000000000232 91.0
HFD3_k127_84213_18 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.00000479 55.0
HFD3_k127_84213_19 Nuclear mitotic apparatus protein 1 K16808 GO:0000132,GO:0000226,GO:0000235,GO:0000278,GO:0000922,GO:0001578,GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005818,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005886,GO:0005938,GO:0006355,GO:0006357,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007088,GO:0007163,GO:0007346,GO:0008017,GO:0008022,GO:0008092,GO:0008150,GO:0008289,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010638,GO:0010646,GO:0010647,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016363,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0019904,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030010,GO:0030425,GO:0030510,GO:0030513,GO:0030856,GO:0030858,GO:0030863,GO:0030953,GO:0030981,GO:0031110,GO:0031112,GO:0031113,GO:0031116,GO:0031122,GO:0031323,GO:0031326,GO:0031334,GO:0031616,GO:0031974,GO:0031981,GO:0032271,GO:0032273,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0032886,GO:0032887,GO:0032888,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0035091,GO:0035371,GO:0036449,GO:0036477,GO:0040001,GO:0042634,GO:0042635,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0044085,GO:0044087,GO:0044089,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045595,GO:0045597,GO:0045604,GO:0045606,GO:0045616,GO:0045618,GO:0045682,GO:0045684,GO:0045787,GO:0045840,GO:0045931,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050793,GO:0050794,GO:0051010,GO:0051011,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051225,GO:0051233,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051293,GO:0051294,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051726,GO:0051783,GO:0051785,GO:0051797,GO:0051798,GO:0051983,GO:0051984,GO:0055028,GO:0055048,GO:0060236,GO:0060255,GO:0060341,GO:0061673,GO:0062033,GO:0065007,GO:0070013,GO:0070507,GO:0070840,GO:0070925,GO:0071840,GO:0071944,GO:0072686,GO:0080090,GO:0090068,GO:0090092,GO:0090100,GO:0090169,GO:0090224,GO:0090235,GO:0090287,GO:0097427,GO:0097431,GO:0097435,GO:0097447,GO:0097458,GO:0097574,GO:0097575,GO:0097718,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110028,GO:0120025,GO:0120038,GO:1902115,GO:1902117,GO:1902363,GO:1902365,GO:1902846,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903506,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904776,GO:1904778,GO:1905720,GO:1905818,GO:1905820,GO:1905832,GO:1990023,GO:1990752,GO:2000026,GO:2000112,GO:2001141,GO:2001252 - 0.0002265 54.0
HFD3_k127_84213_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 516.0
HFD3_k127_84213_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 385.0
HFD3_k127_84213_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 342.0
HFD3_k127_84213_5 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 322.0
HFD3_k127_84213_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000001809 213.0
HFD3_k127_84213_7 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000008008 198.0
HFD3_k127_84213_8 dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000008839 193.0
HFD3_k127_84213_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000001958 178.0
HFD3_k127_84547_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 9.992e-208 655.0
HFD3_k127_84547_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 512.0
HFD3_k127_84547_10 - - - - 0.00000000001216 71.0
HFD3_k127_84547_11 NMT1-like family - - - 0.00000000002396 75.0
HFD3_k127_84547_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000001834 72.0
HFD3_k127_84547_2 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 499.0
HFD3_k127_84547_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 434.0
HFD3_k127_84547_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 444.0
HFD3_k127_84547_5 L-malate dehydrogenase activity K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 375.0
HFD3_k127_84547_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
HFD3_k127_84547_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000002016 166.0
HFD3_k127_84547_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000007475 177.0
HFD3_k127_84547_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000003818 169.0
HFD3_k127_868253_0 Bacterial protein of unknown function (DUF853) - - - 1.18e-232 727.0
HFD3_k127_868253_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 613.0
HFD3_k127_868253_10 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 317.0
HFD3_k127_868253_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
HFD3_k127_868253_12 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007123 288.0
HFD3_k127_868253_13 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000226 272.0
HFD3_k127_868253_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001887 255.0
HFD3_k127_868253_15 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000001249 204.0
HFD3_k127_868253_16 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000001211 178.0
HFD3_k127_868253_17 PFAM Na H antiporter MnhB subunit-related protein - - - 0.000000000000000000000000000000000001225 146.0
HFD3_k127_868253_18 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000708 144.0
HFD3_k127_868253_19 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000002004 149.0
HFD3_k127_868253_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 589.0
HFD3_k127_868253_20 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000941 136.0
HFD3_k127_868253_21 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.0000000000000000000000000000002466 125.0
HFD3_k127_868253_22 multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000003917 126.0
HFD3_k127_868253_23 - - - - 0.000000000000000000000000000004311 130.0
HFD3_k127_868253_24 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000002877 122.0
HFD3_k127_868253_25 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000003243 122.0
HFD3_k127_868253_26 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000003697 120.0
HFD3_k127_868253_27 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000356 110.0
HFD3_k127_868253_28 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000005355 109.0
HFD3_k127_868253_29 - - - - 0.0000000000000000000000006286 111.0
HFD3_k127_868253_3 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 567.0
HFD3_k127_868253_30 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000001433 115.0
HFD3_k127_868253_31 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.0000000000000000000000127 109.0
HFD3_k127_868253_32 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000002836 106.0
HFD3_k127_868253_33 - - - - 0.000000000000000000002821 97.0
HFD3_k127_868253_34 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000001453 94.0
HFD3_k127_868253_35 Na H antiporter, MnhB K05566 - - 0.00000000000000000003104 95.0
HFD3_k127_868253_36 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000001119 97.0
HFD3_k127_868253_37 Belongs to the universal stress protein A family - - - 0.00000000000000003451 88.0
HFD3_k127_868253_38 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000001114 90.0
HFD3_k127_868253_39 Domain of unknown function (DUF4040) K05566 - - 0.0000000000000002844 81.0
HFD3_k127_868253_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05561,K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 503.0
HFD3_k127_868253_40 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000001469 88.0
HFD3_k127_868253_41 NMT1-like family - - - 0.00000000000001278 85.0
HFD3_k127_868253_42 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000001246 82.0
HFD3_k127_868253_43 NMT1-like family K02051 - - 0.000000000002811 77.0
HFD3_k127_868253_44 NMT1-like family K02051 - - 0.000000000004296 77.0
HFD3_k127_868253_46 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000002336 59.0
HFD3_k127_868253_47 Protein of unknown function (DUF1646) - - - 0.000007611 51.0
HFD3_k127_868253_48 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.0002151 48.0
HFD3_k127_868253_5 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 486.0
HFD3_k127_868253_6 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 438.0
HFD3_k127_868253_7 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 385.0
HFD3_k127_868253_8 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 382.0
HFD3_k127_868253_9 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 370.0
HFD3_k127_892635_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 571.0
HFD3_k127_892635_1 FAD binding domain K05898,K13796 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 458.0
HFD3_k127_892635_10 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000001779 202.0
HFD3_k127_892635_11 Reductive dehalogenase subunit - - - 0.000000000000000000000000000000000000000000000000009401 196.0
HFD3_k127_892635_12 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000001039 190.0
HFD3_k127_892635_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000001675 192.0
HFD3_k127_892635_14 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000001901 193.0
HFD3_k127_892635_15 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000001626 172.0
HFD3_k127_892635_16 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000002132 160.0
HFD3_k127_892635_17 4Fe-4S binding domain - - - 0.00000000000000000000000000000004243 128.0
HFD3_k127_892635_18 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000005348 124.0
HFD3_k127_892635_19 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000001654 109.0
HFD3_k127_892635_2 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 410.0
HFD3_k127_892635_20 Fic/DOC family K07341 - - 0.000000000000000000005701 93.0
HFD3_k127_892635_21 - - - - 0.00000000000000000008822 94.0
HFD3_k127_892635_22 Regulatory protein, FmdB family - - - 0.0000000000000000002024 92.0
HFD3_k127_892635_23 Fic/DOC family K07341 - - 0.0000000000002258 71.0
HFD3_k127_892635_24 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.000000006949 61.0
HFD3_k127_892635_25 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000009535 66.0
HFD3_k127_892635_27 Set domain-containing protein K11430 - 2.1.1.43 0.00002729 53.0
HFD3_k127_892635_28 PFAM luciferase family protein - - - 0.00005963 48.0
HFD3_k127_892635_29 Ribosomal protein L7/L12 C-terminal domain - - - 0.0001277 49.0
HFD3_k127_892635_3 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 293.0
HFD3_k127_892635_4 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 252.0
HFD3_k127_892635_5 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000006727 233.0
HFD3_k127_892635_6 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000003482 214.0
HFD3_k127_892635_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000448 226.0
HFD3_k127_892635_8 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000001535 215.0
HFD3_k127_892635_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000001003 207.0
HFD3_k127_894942_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 1.004e-286 889.0
HFD3_k127_894942_1 Thiamine pyrophosphate enzyme, central domain - - - 2.302e-242 761.0
HFD3_k127_894942_2 Thiamine pyrophosphate enzyme, central domain - - - 4.975e-237 746.0
HFD3_k127_894942_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 579.0
HFD3_k127_894942_4 - - - - 0.00000000000000000000000000000000000000000336 155.0
HFD3_k127_894942_5 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000007781 140.0
HFD3_k127_894942_6 - - - - 0.0000000000003322 77.0
HFD3_k127_894942_7 NMT1-like family K02051,K15551 - - 0.00000000001633 76.0
HFD3_k127_894942_8 Helix-turn-helix domain - - - 0.00000000002599 66.0
HFD3_k127_898591_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.179e-255 807.0
HFD3_k127_898591_1 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000001947 221.0
HFD3_k127_898591_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002227 204.0
HFD3_k127_898591_4 phosphinothricin N-acetyltransferase activity K03823,K18816 - 2.3.1.183,2.3.1.82 0.00000000000204 76.0
HFD3_k127_898591_5 Cupin domain - - - 0.00000000005728 68.0
HFD3_k127_901370_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 440.0
HFD3_k127_901370_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 415.0
HFD3_k127_901370_2 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 367.0
HFD3_k127_901370_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 356.0
HFD3_k127_901370_4 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
HFD3_k127_901370_5 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008287 258.0
HFD3_k127_901370_6 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000004886 142.0
HFD3_k127_901370_7 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000007062 126.0
HFD3_k127_92632_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 466.0
HFD3_k127_92632_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 435.0
HFD3_k127_92632_2 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 381.0
HFD3_k127_92632_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000697 110.0
HFD3_k127_926770_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.479e-203 651.0
HFD3_k127_926770_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 482.0
HFD3_k127_926770_2 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 375.0
HFD3_k127_926770_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 347.0
HFD3_k127_926770_4 Wzy family polymerase, exosortase system type 1 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001227 270.0
HFD3_k127_926770_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000009699 113.0
HFD3_k127_926770_6 Fibronectin type 3 domain K01218 - 3.2.1.78 0.000000000000000000006943 109.0
HFD3_k127_926770_7 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.000000000000000002996 101.0
HFD3_k127_933044_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 3.943e-203 663.0
HFD3_k127_933044_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 357.0
HFD3_k127_933044_2 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000001086 230.0
HFD3_k127_933044_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000008098 218.0
HFD3_k127_933044_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000001949 218.0
HFD3_k127_933044_5 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000568 172.0
HFD3_k127_933044_6 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000005176 126.0
HFD3_k127_933044_7 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000002211 82.0
HFD3_k127_938835_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 427.0
HFD3_k127_938835_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 398.0
HFD3_k127_938835_10 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000002789 138.0
HFD3_k127_938835_11 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000003416 68.0
HFD3_k127_938835_12 AntiSigma factor K07167 - - 0.0000004108 57.0
HFD3_k127_938835_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HFD3_k127_938835_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
HFD3_k127_938835_4 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007475 265.0
HFD3_k127_938835_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000557 196.0
HFD3_k127_938835_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000004308 177.0
HFD3_k127_938835_7 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001564 151.0
HFD3_k127_938835_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000004754 154.0
HFD3_k127_938835_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000008283 134.0
HFD3_k127_939158_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 419.0
HFD3_k127_939158_1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
HFD3_k127_939158_2 Nitroreductase family - - - 0.000000000000000000031 98.0
HFD3_k127_939158_3 Cupin domain - - - 0.0000000000000002459 83.0
HFD3_k127_939158_4 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.000000000166 71.0
HFD3_k127_939158_5 FecR protein - - - 0.0005883 50.0
HFD3_k127_949234_0 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 411.0
HFD3_k127_949234_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000007595 154.0
HFD3_k127_952450_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004247 282.0
HFD3_k127_952450_1 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000001477 178.0
HFD3_k127_952450_2 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000002056 175.0
HFD3_k127_952450_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000002567 164.0
HFD3_k127_952450_4 Glyoxalase-like domain - - - 0.000000000000007747 80.0
HFD3_k127_957136_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 602.0
HFD3_k127_957136_1 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 454.0
HFD3_k127_957136_10 Putative DNA-binding domain - - - 0.0000005471 52.0
HFD3_k127_957136_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
HFD3_k127_957136_3 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005793 233.0
HFD3_k127_957136_4 Protein conserved in bacteria K04750 - - 0.000000000000000000000000000000000000000000000000000000000003016 211.0
HFD3_k127_957136_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000971 186.0
HFD3_k127_957136_6 SnoaL-like domain K04750 - - 0.000000000000000000000000000000000000000000000003448 177.0
HFD3_k127_957136_7 YCII-related domain - - - 0.00000000000000000000003295 104.0
HFD3_k127_957136_8 Putative DNA-binding domain - - - 0.000000000000001637 85.0
HFD3_k127_957136_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000326 74.0
HFD3_k127_960858_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.402e-267 843.0
HFD3_k127_960858_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 492.0
HFD3_k127_960858_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002747 256.0
HFD3_k127_960858_11 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000001862 239.0
HFD3_k127_960858_12 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000001803 235.0
HFD3_k127_960858_13 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000003713 222.0
HFD3_k127_960858_14 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000009617 224.0
HFD3_k127_960858_15 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000001364 222.0
HFD3_k127_960858_16 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000003387 128.0
HFD3_k127_960858_17 regulation of translation K03530,K05788 - - 0.000000000000000000000000003081 114.0
HFD3_k127_960858_18 Tetratricopeptide repeat - - - 0.00000000000000000000000003281 119.0
HFD3_k127_960858_19 - - - - 0.0000000000000151 81.0
HFD3_k127_960858_2 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 510.0
HFD3_k127_960858_20 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000001076 70.0
HFD3_k127_960858_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 441.0
HFD3_k127_960858_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 427.0
HFD3_k127_960858_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 325.0
HFD3_k127_960858_6 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 332.0
HFD3_k127_960858_7 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 303.0
HFD3_k127_960858_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001266 261.0
HFD3_k127_960858_9 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HFD3_k127_969975_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 522.0
HFD3_k127_969975_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 393.0
HFD3_k127_969975_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 335.0
HFD3_k127_969975_3 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000004334 179.0
HFD3_k127_969975_4 Protein of unknown function (DUF433) - - - 0.000000000000000000001009 100.0
HFD3_k127_969975_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000001185 82.0
HFD3_k127_969975_6 - - - - 0.0008996 43.0
HFD3_k127_971319_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.059e-290 909.0
HFD3_k127_971319_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.153e-271 851.0
HFD3_k127_971319_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 569.0
HFD3_k127_971319_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 560.0
HFD3_k127_971319_4 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 402.0
HFD3_k127_971319_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
HFD3_k127_971319_6 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000463 177.0
HFD3_k127_971319_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000401 124.0
HFD3_k127_971319_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000001714 104.0
HFD3_k127_971319_9 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000001199 109.0
HFD3_k127_971464_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 590.0
HFD3_k127_971464_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 579.0
HFD3_k127_971464_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 322.0
HFD3_k127_971464_3 Binding-protein-dependent transport system inner membrane component K02011,K02063 - - 0.000000000000000000000000000386 115.0
HFD3_k127_971464_4 - - - - 0.00000000004445 66.0
HFD3_k127_971464_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000001931 60.0
HFD3_k127_975398_0 PFAM type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 552.0
HFD3_k127_975398_1 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000591 211.0
HFD3_k127_975398_2 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000004449 191.0
HFD3_k127_975398_3 PFAM Type II secretion system F K12511 - - 0.000000000000000000000000000000000000000000001882 176.0
HFD3_k127_975398_4 PFAM Type II secretion system F K12510 - - 0.000000000000000000000000000000000000000009986 168.0
HFD3_k127_975398_5 Pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000002953 141.0
HFD3_k127_975398_6 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000001492 98.0
HFD3_k127_996538_0 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 473.0
HFD3_k127_996538_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000351 200.0
HFD3_k127_996538_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000002219 194.0
HFD3_k127_996538_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000001859 174.0
HFD3_k127_996538_4 NMT1-like family - - - 0.000000000000000000000000000000003609 141.0
HFD3_k127_996538_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000001117 98.0